Michelle C. Mendoza, Ph.D.

Affiliations: 
2005 University of California, San Diego, La Jolla, CA 
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"Michelle Mendoza"
Mean distance: 17.75 (cluster 11)
 
SNBCP

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Richard Firtel grad student 2005 UCSD
 (Dysregulated PP4C/PP4R2/SMEK phosphatase activity mediates the Dictyostelium mek1(-) defects in cell polarization, chemotaxis, and gene expression.)
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Publications

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Samson SC, Khan AM, Mendoza MC. (2022) ERK signaling for cell migration and invasion. Frontiers in Molecular Biosciences. 9: 998475
Kircher DA, Trombetti KA, Silvis MR, et al. (2020) Abstract 2736: AKT1E17Kactivates focal adhesion kinase and promotes melanoma brain metastasis Tumor Biology
Samson SC, Elliott A, Mueller BD, et al. (2019) p90 ribosomal S6 kinase (RSK) phosphorylates myosin phosphatase and thereby controls edge dynamics during cell migration. The Journal of Biological Chemistry
Kircher DA, Trombetti KA, Silvis MR, et al. (2019) AKT1E17K activates focal adhesion kinase and promotes melanoma brain metastasis. Molecular Cancer Research : McR
Mendoza MC, Vilela M, Juarez JE, et al. (2015) ERK reinforces actin polymerization to power persistent edge protrusion during motility. Science Signaling. 8: ra47
Er EE, Mendoza MC, Mackey AM, et al. (2013) AKT facilitates EGFR trafficking and degradation by phosphorylating and activating PIKfyve. Science Signaling. 6: ra45
Mendoza MC. (2013) Phosphoregulation of the WAVE regulatory complex and signal integration. Seminars in Cell & Developmental Biology. 24: 272-9
Zhang W, Mendoza MC, Pei X, et al. (2012) Down-regulation of CMTM8 induces epithelial-to-mesenchymal transition-like changes via c-MET/extracellular signal-regulated kinase (ERK) signaling. The Journal of Biological Chemistry. 287: 11850-8
Mendoza MC, Er EE, Blenis J. (2011) The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation. Trends in Biochemical Sciences. 36: 320-8
Mendoza MC, Er EE, Zhang W, et al. (2011) ERK-MAPK drives lamellipodia protrusion by activating the WAVE2 regulatory complex. Molecular Cell. 41: 661-71
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