Roderick MacKinnon
Affiliations: | Rockefeller University, New York, NY, United States |
Area:
Ion channelsWebsite:
https://www.rockefeller.edu/our-scientists/heads-of-laboratories/872-roderick-mackinnon/Google:
"Roderick MacKinnon"Bio:
The Nobel Prize in Chemistry 2003 was awarded "for discoveries concerning channels in cell membranes" jointly with one half to Peter Agre "for the discovery of water channels" and with one half to Roderick MacKinnon "for structural and mechanistic studies of ion channels".
http://www.nasonline.org/member-directory/members/3009152.html
http://lab.rockefeller.edu/mackinnon/
http://www.hhmi.org/scientists/roderick-mackinnon
http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2003/mackinnon-facts.html
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Mean distance: 14.1 (cluster 11) | S | N | B | C | P |
Cross-listing: Chemistry Tree
Children
Sign in to add trainee| Alexander R. Pico | grad student | 1998-2003 | Rockefeller (Chemistry Tree) |
| Vanessa Ruta | grad student | 1999-2005 | Rockefeller |
| Declan A. Doyle | post-doc | Rockefeller | |
| Liang Feng | post-doc | Rockefeller | |
| Richard K. Hite | post-doc | Rockefeller (Chemistry Tree) | |
| Qiu-Xing Jiang | post-doc | ||
| Youxing Jiang | post-doc | Rockefeller (Computational Biology Tree) | |
| Seok-Yong Lee | post-doc | Rockefeller (Chemistry Tree) | |
| Stephen B. Long | post-doc | (Chemistry Tree) | |
| Eunyong Park | post-doc | (Cell Biology Tree) | |
| Gonzalo Perez-Mitta | post-doc | Rockefeller (Chemistry Tree) | |
| Rama Ranganathan | post-doc | Harvard Medical School (FlyTree) | |
| Stephen G. Brohawn | post-doc | 2010- | Rockefeller |
| Ji Sun | post-doc | 2014- | Rockefeller (Chemistry Tree) |
| Chinfei Chen | post-doc | 1995-1996 | Harvard Medical School |
| Kenton Jon Swartz | post-doc | 1993-1997 | Harvard Medical School |
| Ming Zhou | post-doc | 1999-2004 | Rockefeller (Chemistry Tree) |
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Publications
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| Zhang Y, Mazal H, Mandala VS, et al. (2024) Higher-order transient membrane protein structures. Proceedings of the National Academy of Sciences of the United States of America. 122: e2421275121 |
| Pérez-Mitta G, Sezgin Y, Wang W, et al. (2024) Freestanding bilayer microscope for single-molecule imaging of membrane proteins. Science Advances. 10: eado4722 |
| Mandala VS, MacKinnon R. (2023) The membrane electric field regulates the PIP-binding site to gate the KCNQ1 channel. Proceedings of the National Academy of Sciences of the United States of America. 120: e2301985120 |
| Tao X, Zhao C, MacKinnon R. (2023) Membrane protein isolation and structure determination in cell-derived membrane vesicles. Proceedings of the National Academy of Sciences of the United States of America. 120: e2302325120 |
| Pérez-Mitta G, MacKinnon R. (2023) Freestanding lipid bilayer tensiometer for the study of mechanosensitive ion channels. Proceedings of the National Academy of Sciences of the United States of America. 120: e2221541120 |
| Mandala VS, MacKinnon R. (2022) Voltage-sensor movements in the Eag Kv channel under an applied electric field. Proceedings of the National Academy of Sciences of the United States of America. 119: e2214151119 |
| Zhao C, MacKinnon R. (2022) Structural and functional analyses of a GPCR-inhibited ion channel TRPM3. Neuron |
| Zhang Y, Tao X, MacKinnon R. (2022) Correlation between structure and function in phosphatidylinositol lipid-dependent Kir2.2 gating. Proceedings of the National Academy of Sciences of the United States of America. 119: e2114046119 |
| Zhao C, MacKinnon R. (2021) Molecular structure of an open human K channel. Proceedings of the National Academy of Sciences of the United States of America. 118 |
| Niu Y, Tao X, Vaisey G, et al. (2021) Analysis of the mechanosensor channel functionality of TACAN. Elife. 10 |