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Irwin J. Kopin

Affiliations: 
National Institute of Neurological Disorders and Stroke, Bethesda, MD, United States 
Area:
Dopamine, Parkinson's Disease
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"Irwin Kopin"
Mean distance: 13.74 (cluster 6)
 		SNBCP
Cross-listing: Neuropathology Tree

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Parents

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Seymour S. Kety post-doc 1957-1963 NIMH
Julius Axelrod research scientist 1963-1968 NIMH

Children

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Fred Goodwin post-doc NINDS
Richard C. McCarty post-doc NINDS
George R. Breese post-doc 1966-1968 NIMH
John (Steven) Kizer post-doc 1972-1975 NIMH
Joseph J. Schildkraut research scientist 1966-1967 NIMH

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Publications

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Goldstein DS, Holmes C, Sullivan P, et al. (2016) Elevated cerebrospinal fluid ratios of cysteinyl-dopamine/3,4-dihydroxyphenylacetic acid in parkinsonian synucleinopathies. Parkinsonism & Related Disorders
Goldstein DS, Jinsmaa Y, Sullivan P, et al. (2016) 3,4-Dihydroxyphenylethanol (Hydroxytyrosol) Mitigates the Increase in Spontaneous Oxidation of Dopamine During Monoamine Oxidase Inhibition in PC12 Cells. Neurochemical Research
Goldstein DS, Jinsmaa Y, Sullivan P, et al. (2015) Comparison of monoamine oxidase inhibitors in decreasing production of the autotoxic dopamine metabolite 3,4-dihydroxyphenylacetaldehyde (DOPAL) in PC12 cells. The Journal of Pharmacology and Experimental Therapeutics
Goldstein DS, Holmes C, Sullivan P, et al. (2015) Deficient vesicular storage: A common theme in catecholaminergic neurodegeneration. Parkinsonism & Related Disorders. 21: 1013-22
Goldstein DS, Sullivan P, Cooney A, et al. (2015) Rotenone decreases intracellular aldehyde dehydrogenase activity: implications for the pathogenesis of Parkinson's disease. Journal of Neurochemistry. 133: 14-25
Goldstein DS, Sullivan P, Cooney A, et al. (2012) Vesicular uptake blockade generates the toxic dopamine metabolite 3,4-dihydroxyphenylacetaldehyde in PC12 cells: relevance to the pathogenesis of Parkinson's disease. Journal of Neurochemistry. 123: 932-43
Eisenhofer G, Goldstein D, Kopin I. (2009) Simultaneous liquid-chromatographic determination of plasma catecholamines and metabolites Clinical Chemistry. 55: 2223-2224
Eisenhofer G, Kopin IJ, Goldstein DS. (2004) Catecholamine metabolism: a contemporary view with implications for physiology and medicine. Pharmacological Reviews. 56: 331-49
Eisenhofer G, Kopin IJ, Goldstein DS. (2004) Leaky catecholamine stores: undue waste or a stress response coping mechanism? Annals of the New York Academy of Sciences. 1018: 224-30
Eldadah BA, Pacak K, Eisenhofer G, et al. (2004) Cardiac uptake-1 inhibition by high circulating norepinephrine levels in patients with pheochromocytoma. Hypertension. 43: 1227-32
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