Michael R. Hayden

University of British Columbia, Vancouver, Vancouver, BC, Canada 
Biostatistics Biology
"Michael Hayden"
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Cross-listing: MathTree


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Katherine J. Ashbourne Excoffon grad student 2000 UBC (MathTree)
Susanne M. Clee grad student 2001 UBC (MathTree)
Ryan R. Brinkman grad student 2002 UBC (MathTree)
Elizabeth J. Slow grad student 2005 UBC (MathTree)
Jeremy M. Van Raamsdonk grad student 2005 UBC
Mahmoud A Pouladi grad student 2003-2010 UBC
Amber L. Southwell post-doc 2009-2016 UBC
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Ehrnhoefer DE, Skotte NH, Reinshagen J, et al. (2019) Activation of Caspase-6 Is Promoted by a Mutant Huntingtin Fragment and Blocked by an Allosteric Inhibitor Compound. Cell Chemical Biology
Smith-Dijak AI, Nassrallah WB, Zhang LYJ, et al. (2019) Impairment and Restoration of Homeostatic Plasticity in Cultured Cortical Neurons From a Mouse Model of Huntington Disease. Frontiers in Cellular Neuroscience. 13: 209
Ferrari Bardile C, Garcia-Miralles M, Caron NS, et al. (2019) Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease. Proceedings of the National Academy of Sciences of the United States of America
Kang R, Wang L, Sanders SS, et al. (2019) Altered Regulation of Striatal Neuronal -Methyl-D-Aspartate Receptor Trafficking by Palmitoylation in Huntington Disease Mouse Model. Frontiers in Synaptic Neuroscience. 11: 3
Johnston TH, Geva M, Steiner L, et al. (2018) Pridopidine, a clinic-ready compound, reduces 3,4-dihydroxyphenylalanine-induced dyskinesia in Parkinsonian macaques. Movement Disorders : Official Journal of the Movement Disorder Society
Garcia-Miralles M, Yusof NABM, Tan JY, et al. (2018) Laquinimod Treatment Improves Myelination Deficits at the Transcriptional and Ultrastructural Levels in the YAC128 Mouse Model of Huntington Disease. Molecular Neurobiology
Southwell AL, Kordasiewicz HB, Langbehn D, et al. (2018) Huntingtin suppression restores cognitive function in a mouse model of Huntington's disease. Science Translational Medicine. 10
Caron NS, Dorsey ER, Hayden MR. (2018) Therapeutic approaches to Huntington disease: from the bench to the clinic. Nature Reviews. Drug Discovery
Schmidt ME, Buren C, Mackay JP, et al. (2018) Altering cortical input unmasks synaptic phenotypes in the YAC128 cortico-striatal co-culture model of Huntington disease. Bmc Biology. 16: 58
Kusko R, Dreymann J, Ross J, et al. (2018) Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse. Molecular Neurodegeneration. 13: 25
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