Elias Aizenman, Ph.D.

Affiliations: 
1989- Neurobiology University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Zinc, Potassium Channels, Apoptosis, Redox, NMDA, TOPA
Website:
http://aizenmanlab.neurobio.pitt.edu/
Google:
"Elias Aizenman"
Mean distance: 13.23 (cluster 11)
 
SNBCP

Parents

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Chirstopher H. Price research assistant 1980-1981 Boston University
George G. Bierkamper grad student 1981-1985 Johns Hopkins
Elise F. Stanley grad student 1981-1985 Johns Hopkins
Stuart A. Lipton post-doc 1985-1987 Harvard Medical School
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Publications

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Krall RF, Moutal A, Phillips MB, et al. (2020) Synaptic zinc inhibition of NMDA receptors depends on the association of GluN2A with the zinc transporter ZnT1. Science Advances. 6
Schulien AJ, Yeh CY, Orange BN, et al. (2020) Targeted disruption of Kv2.1-VAPA association provides neuroprotection against ischemic stroke in mice by declustering Kv2.1 channels. Science Advances. 6
Yeh CY, Schulien AJ, Molyneaux BJ, et al. (2020) Lessons from Recent Advances in Ischemic Stroke Management and Targeting Kv2.1 for Neuroprotection. International Journal of Molecular Sciences. 21
Aizenman E, Loring RH, Reynolds IJ, et al. (2020) The Redox Biology of Excitotoxic Processes: The NMDA Receptor, TOPA Quinone, and the Oxidative Liberation of Intracellular Zinc. Frontiers in Neuroscience. 14: 778
XiangWei W, Kannan V, Xu Y, et al. (2019) Heterogeneous clinical and functional features of GRIN2D-related developmental and epileptic encephalopathy. Brain : a Journal of Neurology
Yeh CY, Ye Z, Moutal A, et al. (2019) Defining the Kv2.1-syntaxin molecular interaction identifies a first-in-class small molecule neuroprotectant. Proceedings of the National Academy of Sciences of the United States of America
Justice JA, Manjooran DT, Yeh CY, et al. (2018) Molecular neuroprotection induced by zinc-dependent expression of hepatitis C-derived protein NS5A targeting Kv2.1 potassium channels. The Journal of Pharmacology and Experimental Therapeutics
Yeh CY, Bulas AM, Moutal A, et al. (2017) Targeting a Potassium Channel/Syntaxin Interaction Ameliorates Cell Death in Ischemic Stroke. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Justice JA, Schulien AJ, He K, et al. (2017) Disruption of KV2.1 somato-dendritic clusters prevents the apoptogenic increase of potassium currents. Neuroscience
Ogden KK, Chen W, Swanger SA, et al. (2017) Molecular Mechanism of Disease-Associated Mutations in the Pre-M1 Helix of NMDA Receptors and Potential Rescue Pharmacology. Plos Genetics. 13: e1006536
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