Aaron D. Gitler

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
 Stanford University, Palo Alto, CA 
Area:
Genetics
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"Aaron Gitler"
Mean distance: 15.77 (cluster 32)
 
SNBCP

Parents

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Jonathan A. Epstein grad student 2004 Penn
 (Endothelial cell signaling pathways in cardiovascular development: Vascular/neural connections.)
Susan L. Lindquist post-doc 2004-2007 Whitehead Institute (FlyTree)

Children

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Joseph W Paul research assistant 2014-2015 (Cell Biology Tree)
Maria Armakola grad student 2012 Penn
Michael P. Hart grad student 2012 Penn
Matthew Figley grad student 2012-2015 Stanford
Ana Jovicic post-doc 2012-2016 Stanford

Collaborators

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Nancy Mara Bonini collaborator 2004- Penn
BETA: Related publications

Publications

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Gittings LM, Boeynaems S, Lightwood D, et al. (2019) Symmetric dimethylation of poly-GR correlates with disease duration in C9orf72 FTLD and ALS and reduces poly-GR phase separation and toxicity. Acta Neuropathologica
Boeynaems S, Gitler AD. (2019) Axons Gonna Ride 'til They Can't No More. Neuron. 104: 179-181
Yamada SB, Gendron TF, Niccoli T, et al. (2019) RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats. Nature Neuroscience
Goodman LD, Prudencio M, Kramer NJ, et al. (2019) Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD. Nature Neuroscience
Bieri G, Brahic M, Bousset L, et al. (2019) LRRK2 modifies α-syn pathology and spread in mouse models and human neurons. Acta Neuropathologica
Boeynaems S, Holehouse AS, Weinhardt V, et al. (2019) Spontaneous driving forces give rise to protein-RNA condensates with coexisting phases and complex material properties. Proceedings of the National Academy of Sciences of the United States of America
Boeynaems S, Gitler AD. (2018) Pour Some Sugar on TDP(-43). Molecular Cell. 71: 649-651
Zhang YJ, Gendron TF, Ebbert MTW, et al. (2018) Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis. Nature Medicine
Boeynaems S, Gitler AD. (2018) Phosphorylation Leads the Way for Protein Aggregate Disassembly. Developmental Cell. 45: 279-281
Guo L, Kim HJ, Wang H, et al. (2018) Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains. Cell. 173: 677-692.e20
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