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Gary Ruvkun

Affiliations: 
1985- Genetics Harvard Medical School and Massachusetts General Hospital, Boston, MA, United States 
Area:
miRNA, C. elegans development and lifespan
Website:
https://www.ruvkun.hms.harvard.edu/
Google:
"Gary Bruce Ruvkun"
Bio:

(born 1952)
The Nobel Prize in Physiology or Medicine 2024 was awarded jointly to Victor Ambros and Gary Ruvkun "for the discovery of microRNA and its role in post-transcriptional gene regulation."
https://en.wikipedia.org/wiki/Gary_Ruvkun
http://news.harvard.edu/gazette/story/2008/11/microbiologist-gary-ruvkun/

Mean distance: 14.92 (cluster 57)
 		SNBCP
Cross-listing: Cell Biology Tree - Chemistry Tree

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Parents

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Frederick Michael Ausubel grad student 1977-1982 Harvard (Chemistry Tree)
 (The molecular genetic analysis of symbiotic nitrogen fixation genes from Rhizobium meliloti)
Walter Gilbert post-doc Harvard (Chemistry Tree)
H. Robert Horvitz post-doc MIT

Children

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Scott G. Kennedy grad student Harvard Medical School - Massachusetts General Hospital
Koutarou D. Kimura grad student
Peter Barrett grad student 1993-1999 Harvard
Gisela M. Sandoval grad student 2004 Harvard
Duo Wang grad student 2005 Harvard
Gabriel D. Hayes grad student 2006 Harvard
Maurice D. Butler grad student 2008 Harvard
Harrison W. Gabel grad student 2008 Harvard
Sascha E. Russel grad student 2011 Harvard
Zhen Shi grad student 2013 Harvard
Jacob C. Carlson grad student 2014-2016 Harvard (Chemistry Tree)
Kaveh Ashrafi post-doc
Oliver Hobert post-doc Columbia
Carolyn Phillips post-doc (Cell Biology Tree)
Ilya Ruvinsky post-doc Harvard Medical School and Massachusetts General Hospital (Evolution Tree)
Frank J. Slack post-doc Harvard Medical School (Chemistry Tree)
Justine A. Melo post-doc 2004- (Chemistry Tree)
David Greenstein post-doc 1989-1994 Massachusetts General Hospital / Harvard Medical School (GenetiTree)
Thomas Anthony Isenbarger post-doc 2001-2004 Harvard Medical School & Massachuestts General Hospital (Evolution Tree)
Buck S. Samuel post-doc 2008-2014 MGH & Harvard Medical School (Microtree)

Collaborators

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Publications

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Xu W, Sun Y, Breen P, et al. (2024) inositol hexaphosphate pathways couple to RNA interference and pathogen defense. Proceedings of the National Academy of Sciences of the United States of America. 121: e2416982121
Seetharaman A, Galagali H, Linarte E, et al. (2024) SynMuv B gene activity is down-regulated during a viral infection to enhance RNA interference. Biorxiv : the Preprint Server For Biology
Yanagi KS, Jochim B, Kunjo SO, et al. (2024) Mutations in nucleotide metabolism genes bypass proteasome defects in png-1/NGLY1-deficient Caenorhabditis elegans. Plos Biology. 22: e3002720
Meisel JD, Wiesenthal PP, Mootha VK, et al. (2024) CMTR-1 RNA methyltransferase mutations activate widespread expression of a dopaminergic neuron-specific mitochondrial complex I gene. Current Biology : Cb
Warnhoff K, Bhattacharya S, Snoozy J, et al. (2024) Hypoxia-inducible factor induces cysteine dioxygenase and promotes cysteine homeostasis in . Elife. 12
Meisel JD, Miranda M, Skinner OS, et al. (2024) Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism. Cell
Warnhoff K, Snoozy J, Breen PC, et al. (2023) Hypoxia-inducible factor promotes cysteine homeostasis in . Biorxiv : the Preprint Server For Biology
Mao K, Breen P, Ruvkun G. (2022) The ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways. Proceedings of the National Academy of Sciences of the United States of America. 119: e2215966119
Ruvkun G, Lehrbach N. (2022) Regulation and Functions of the ER-Associated Nrf1 Transcription Factor. Cold Spring Harbor Perspectives in Biology
Ji F, Bonilla G, Krykbaev R, et al. (2022) DEPCOD: a tool to detect and visualize co-evolution of protein domains. Nucleic Acids Research
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