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Gary Ruvkun

Affiliations: 
Genetics Massachusetts General Hospital, Boston, MA 
Area:
miRNA, C. elegans development and lifespan
Website:
http://www.hms.harvard.edu/dms/BBS/fac/ruvkun.php
Google:
"Gary Bruce Ruvkun"
Bio:

http://www.fas.harvard.edu/~biophys/Gary_Ruvkun.htm
http://genetics.med.harvard.edu/faculty/ruvkun
http://ccib.mgh.harvard.edu/ruvkun
http://www.hms.harvard.edu/agingresearch/pages/garyruvkun.htm
http://molbio.mgh.harvard.edu/laboratories/ruvkun
http://ccib.mgh.harvard.edu/ruvkun/pi_bio
http://news.harvard.edu/gazette/story/2008/11/microbiologist-gary-ruvkun/

Mean distance: 14.92 (cluster 57)
 		SNBCP
Cross-listing: Cell Biology Tree - Chemistry Tree

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Parents

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Fred M. Ausubel grad student 1977-1982 Harvard (Chemistry Tree)
 (The molecular genetic analysis of symbiotic nitrogen fixation genes from Rhizobium meliloti)
Walter Gilbert post-doc Harvard (Chemistry Tree)
H. Robert Horvitz post-doc MIT

Children

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Scott G. Kennedy grad student Harvard Medical School - Massachusetts General Hospital
Peter Barrett grad student 1993-1999 Harvard
Gisela M. Sandoval grad student 2004 Harvard
Duo Wang grad student 2005 Harvard
Gabriel D. Hayes grad student 2006 Harvard
Maurice D. Butler grad student 2008 Harvard
Harrison W. Gabel grad student 2008 Harvard
Sascha E. Russel grad student 2011 Harvard
Zhen Shi grad student 2013 Harvard
Jacob C. Carlson grad student 2014-2016 Harvard (Chemistry Tree)
Oliver Hobert post-doc Columbia
Ilya Ruvinsky post-doc Harvard Medical School and Massachusetts General Hospital (Evolution Tree)
Frank J. Slack post-doc Harvard Medical School (Chemistry Tree)
Justine A. Melo post-doc 2004- (Chemistry Tree)
Buck S. Samuel post-doc 2008-2014 MGH & Harvard Medical School (Microtree)

Collaborators

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BETA: Related publications

Publications

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Lehrbach NJ, Breen PC, Ruvkun G. (2019) Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression. Cell. 177: 737-750.e15
Lehrbach NJ, Ruvkun G. (2019) Endoplasmic reticulum-associated SKN-1A/Nrf1 mediates a cytoplasmic unfolded protein response and promotes longevity. Elife. 8
Lin XX, Sen I, Janssens GE, et al. (2018) DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity. Nature Communications. 9: 4400
Tillman EJ, Richardson CE, Cattie DJ, et al. (2018) Endoplasmic Reticulum Homeostasis Is Modulated by the Forkhead Transcription Factor FKH-9 During Infection of . Genetics
Ambros V, Ruvkun G. (2018) Recent Molecular Genetic Explorations of MicroRNAs. Genetics. 209: 651-673
Newman MA, Ji F, Fischer SEJ, et al. (2018) The surveillance of pre-mRNA splicing is an early step in RNAi of endogenous genes. Genes & Development
Lehrbach NJ, Ruvkun G. (2016) Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1. Elife. 5
Dowen RH, Breen PC, Tullius T, et al. (2016) A microRNA program in the C. elegans hypodermis couples to intestinal mTORC2/PQM-1 signaling to modulate fat transport. Genes & Development. 30: 1515-28
Samuel BS, Rowedder H, Braendle C, et al. (2016) Caenorhabditis elegans responses to bacteria from its natural habitats. Proceedings of the National Academy of Sciences of the United States of America
Govindan JA, Jayamani E, Zhang X, et al. (2015) Dialogue between E. coli free radical pathways and the mitochondria of C. elegans. Proceedings of the National Academy of Sciences of the United States of America
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