Tara L. Spires-Jones

University of Edinburgh, Edinburgh, Scotland, United Kingdom 
dendritic spine plasticity, Alzheimer's disease
"Tara Spires-Jones"
Mean distance: 13.8 (cluster 17)
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Yeap J, Sathyaprakash C, Toombs J, et al. (2022) Reducing voltage-dependent potassium channel Kv3.4 levels ameliorates synapse loss in a mouse model of Alzheimer's disease. Brain and Neuroscience Advances. 6: 23982128221086464
King D, Spires-Jones TL. (2022) Tau talk - synaptic and mitochondrial proteins interact with Tau in human neurons. Trends in Neurosciences. 45: 339-341
Jiwaji Z, Tiwari SS, Avilés-Reyes RX, et al. (2022) Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology. Nature Communications. 13: 135
Petrozziello T, Amaral AC, Dujardin S, et al. (2021) Novel genetic variants in MAPT and alterations in tau phosphorylation in amyotrophic lateral sclerosis post-mortem motor cortex and cerebrospinal fluid. Brain Pathology (Zurich, Switzerland). e13035
Petrozziello T, Bordt EA, Mills AN, et al. (2021) Targeting Tau Mitigates Mitochondrial Fragmentation and Oxidative Stress in Amyotrophic Lateral Sclerosis. Molecular Neurobiology
Kurucu H, Colom-Cadena M, Davies C, et al. (2021) Inhibitory synapse loss and accumulation of amyloid beta in inhibitory presynaptic terminals in Alzheimer's disease. European Journal of Neurology
Lin Z, Kim E, Ahmed M, et al. (2021) MRI-guided histology of TDP-43 knock-in mice implicates parvalbumin interneuron loss, impaired neurogenesis and aberrant neurodevelopment in amyotrophic lateral sclerosis-frontotemporal dementia. Brain Communications. 3: fcab114
Izzo NJ, Yuede CM, LaBarbera KM, et al. (2021) Preclinical and clinical biomarker studies of CT1812: A novel approach to Alzheimer's disease modification. Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Largo-Barrientos P, Apóstolo N, Creemers E, et al. (2021) Lowering Synaptogyrin-3 expression rescues Tau-induced memory defects and synaptic loss in the presence of microglial activation. Neuron
Zoupi L, Booker SA, Eigel D, et al. (2021) Selective vulnerability of inhibitory networks in multiple sclerosis. Acta Neuropathologica
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