Victor Ambros
Affiliations: | 1985-1992 | Harvard University, Cambridge, MA, United States | |
1992-2007 | Geisel School of Medicine at Dartmouth, Hanover, NH, United States | ||
2008- | University of Massachusetts Medical School, Worcester, MA, United States |
Area:
miRNA, C. elegans developmentWebsite:
https://www.umassmed.edu/ambroslab/Google:
"Victor Ambros"Bio:
(born 1953)
The Nobel Prize in Physiology or Medicine 2024 was awarded jointly to Victor Ambros and Gary Ruvkun "for the discovery of microRNA and its role in post-transcriptional gene regulation."
https://en.wikipedia.org/wiki/Victor_Ambros
Mean distance: 14.58 (cluster 32) | S | N | B | C | P |
Cross-listing: FlyTree - GenetiTree - DevTree - Cell Biology Tree
Parents
Sign in to add mentorEdward R. Gruberg | research assistant | 1974 | MIT | |
(A forebrain visual projection in the frog (Rana pipiens).) | ||||
John M. Buchanan | research assistant | 1975 | MIT (Chemistry Tree) | |
(Surface ruffles as markers for studies of cell transformation by Rous sarcoma virus.) | ||||
David Baltimore | grad student | 1976-1979 | University of Massachusetts Medical School (Chemistry Tree) | |
(Ph.D. The protein covalently linked to the 5' end of poliovirus RNA.) | ||||
H. Robert Horvitz | post-doc | 1979-1985 | MIT |
Children
Sign in to add traineeZhongchi Liu | grad student | 1990 | University of Maryland (Plant Biology Tree) |
Craig Cameron Mello | grad student | 1990 | Harvard |
Molly Hammell | post-doc | University of Massachusetts Medical School (FlyTree) | |
Xianjie Yang | post-doc | 1988-1989 | Harvard |
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Publications
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Ambros V. (2024) MicroRNA-mediated gene regulation and the resilience of multicellular animals. Postepy Biochemii. 70: 62-70 |
Duan Y, Li L, Panzade GP, et al. (2024) Modeling neurodevelopmental disorder-associated human mutations in Argonaute . Proceedings of the National Academy of Sciences of the United States of America. 121: e2308255121 |
Mirza Z, Walhout AJM, Ambros V. (2023) A bacterial pathogen induces developmental slowing by high reactive oxygen species and mitochondrial dysfunction in Caenorhabditis elegans. Cell Reports. 42: 113189 |
Duan Y, Li L, Panzade GP, et al. (2023) Modeling neurodevelopmental disorder-associated mutations in Argonaute . Biorxiv : the Preprint Server For Biology |
Duan Y, Veksler-Lublinsky I, Ambros V. (2022) Critical contribution of 3' non-seed base pairing to the in vivo function of the evolutionarily conserved let-7a microRNA. Cell Reports. 39: 110745 |
Ilbay O, Nelson C, Ambros V. (2021) C. elegans LIN-28 controls temporal cell fate progression by regulating LIN-46 expression via the 5' UTR of lin-46 mRNA. Cell Reports. 36: 109670 |
Nelson C, Ambros V. (2021) A cohort of Caenorhabditis species lacking the highly conserved let-7 microRNA. G3 (Bethesda, Md.). 11 |
Ambros V. (2021) Development: Keeping Time with Transcription. Current Biology : Cb. 31: R212-R214 |
Duan Y, Choi S, Nelson C, et al. (2020) Engineering essential genes with a "jump board" strategy using CRISPR/Cas9. Micropublication Biology. 2020 |
Vasquez-Rifo A, Ricci EP, Ambros V. (2020) Pseudomonas aeruginosa cleaves the decoding center of Caenorhabditis elegans ribosomes. Plos Biology. 18: e3000969 |