Victor Ambros

Affiliations: 
1985-1992 Harvard University, Cambridge, MA, United States 
 1992-2007 Geisel School of Medicine at Dartmouth, Hanover, NH, United States 
 2008- University of Massachusetts Medical School, Worcester, MA, United States 
Area:
miRNA, C. elegans development
Website:
https://www.umassmed.edu/ambroslab/
Google:
"Victor Ambros"
Bio:

(born 1953)
The Nobel Prize in Physiology or Medicine 2024 was awarded jointly to Victor Ambros and Gary Ruvkun "for the discovery of microRNA and its role in post-transcriptional gene regulation."
https://en.wikipedia.org/wiki/Victor_Ambros

Mean distance: 14.58 (cluster 32)
 
SNBCP
Cross-listing: FlyTree - GenetiTree - DevTree - Cell Biology Tree

Parents

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Edward R. Gruberg research assistant 1974 MIT
 (A forebrain visual projection in the frog (Rana pipiens).)
John M. Buchanan research assistant 1975 MIT (Chemistry Tree)
 (Surface ruffles as markers for studies of cell transformation by Rous sarcoma virus.)
David Baltimore grad student 1976-1979 University of Massachusetts Medical School (Chemistry Tree)
 (Ph.D. The protein covalently linked to the 5' end of poliovirus RNA.)
H. Robert Horvitz post-doc 1979-1985 MIT

Children

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Zhongchi Liu grad student 1990 University of Maryland (Plant Biology Tree)
Craig Cameron Mello grad student 1990 Harvard
Molly Hammell post-doc University of Massachusetts Medical School (FlyTree)
Xianjie Yang post-doc 1988-1989 Harvard
BETA: Related publications

Publications

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Ambros V. (2024) MicroRNA-mediated gene regulation and the resilience of multicellular animals. Postepy Biochemii. 70: 62-70
Duan Y, Li L, Panzade GP, et al. (2024) Modeling neurodevelopmental disorder-associated human mutations in Argonaute . Proceedings of the National Academy of Sciences of the United States of America. 121: e2308255121
Mirza Z, Walhout AJM, Ambros V. (2023) A bacterial pathogen induces developmental slowing by high reactive oxygen species and mitochondrial dysfunction in Caenorhabditis elegans. Cell Reports. 42: 113189
Duan Y, Li L, Panzade GP, et al. (2023) Modeling neurodevelopmental disorder-associated mutations in Argonaute . Biorxiv : the Preprint Server For Biology
Duan Y, Veksler-Lublinsky I, Ambros V. (2022) Critical contribution of 3' non-seed base pairing to the in vivo function of the evolutionarily conserved let-7a microRNA. Cell Reports. 39: 110745
Ilbay O, Nelson C, Ambros V. (2021) C. elegans LIN-28 controls temporal cell fate progression by regulating LIN-46 expression via the 5' UTR of lin-46 mRNA. Cell Reports. 36: 109670
Nelson C, Ambros V. (2021) A cohort of Caenorhabditis species lacking the highly conserved let-7 microRNA. G3 (Bethesda, Md.). 11
Ambros V. (2021) Development: Keeping Time with Transcription. Current Biology : Cb. 31: R212-R214
Duan Y, Choi S, Nelson C, et al. (2020) Engineering essential genes with a "jump board" strategy using CRISPR/Cas9. Micropublication Biology. 2020
Vasquez-Rifo A, Ricci EP, Ambros V. (2020) Pseudomonas aeruginosa cleaves the decoding center of Caenorhabditis elegans ribosomes. Plos Biology. 18: e3000969
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