Stephen F. Traynelis

Rollins Research Center Emory University, Atlanta, GA 
NMDA receptors, Rare Mutations, Epilepsy, Stroke
"Stephen Traynelis"
Mean distance: 13.11 (cluster 11)
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Tang W, Beckley JT, Zhang J, et al. (2023) Novel neuroactive steroids as positive allosteric modulators of NMDA receptors: mechanism, site of action, and rescue pharmacology on GRIN variants associated with neurological conditions. Cellular and Molecular Life Sciences : Cmls. 80: 42
Zaczek R, Traynelis SF, Dingledine R, et al. (2023) Phase 1 Clinical Results for NP10679, a pH-sensitive GluN2B-selective N-methyl-d-aspartate Receptor Inhibitor. Clinical Pharmacology in Drug Development
Montanez-Miranda C, Perszyk RE, Harbin NH, et al. (2022) . Molecular Pharmacology
Chou TH, Kang H, Simorowski N, et al. (2022) Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Molecular Cell
Han W, Yuan H, Allen JP, et al. (2022) . The Journal of Pharmacology and Experimental Therapeutics
Hansen KB, Wollmuth LP, Bowie D, et al. (2021) Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels. Pharmacological Reviews. 73: 298-487
Benke TA, Park K, Krey I, et al. (2021) Clinical and therapeutic significance of genetic variation in the GRIN gene family encoding NMDARs. Neuropharmacology. 108805
Myers SJ, Ruppa KP, Wilson LJ, et al. (2021) . The Journal of Pharmacology and Experimental Therapeutics
Zhang J, Tang W, Bhatia NK, et al. (2021) A Variant Associated With Myoclonus and Developmental Delay: From Molecular Mechanism to Rescue Pharmacology. Frontiers in Genetics. 12: 694312
Perszyk RE, Kristensen AS, Lyuboslavsky P, et al. (2021) Three-dimensional missense tolerance ratio analysis. Genome Research
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