Stephen F. Traynelis

Affiliations: 
Rollins Research Center Emory University, Atlanta, GA 
Area:
NMDA receptors, Rare Mutations, Epilepsy, Stroke
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"Stephen Traynelis"
Mean distance: 13.11 (cluster 11)
 
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Publications

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Xu Y, Song R, Chen W, et al. (2021) Recurrent seizure-related GRIN1 variant: Molecular mechanism and targeted therapy. Annals of Clinical and Translational Neurology
Park H, Han KS, Seo J, et al. (2021) Correction to: Channel-mediated astrocytic glutamate modulates hippocampal synaptic plasticity by activating postsynaptic NMDA receptors. Molecular Brain. 14: 103
Perszyk RE, Yip MC, McConnell OL, et al. (2021) Automated intracellular pharmacological electrophysiology for ligand-gated ionotropic receptor and pharmacology screening. Molecular Pharmacology
Perszyk RE, Zheng Z, Banke TG, et al. (2021) . Molecular Pharmacology
Strong KL, Epplin MP, Ogden KK, et al. (2020) Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of -Methyl-d-aspartate Receptors. Acs Chemical Neuroscience
Tang W, Liu D, Traynelis SF, et al. (2020) Positive allosteric modulators that target NMDA receptors rectify loss-of-function GRIN variants associated with neurological and neuropsychiatric disorders. Neuropharmacology. 108247
Amador A, Bostick CD, Olson H, et al. (2020) Modelling and treating GRIN2A developmental and epileptic encephalopathy in mice. Brain : a Journal of Neurology
Epplin M, Mohan A, Harris L, et al. (2020) The Discovery of Dihydropyrrolo[1,2-a]pyrazin-3(4H)-one-Based Second-Generation GluN2C- and GluN2D-Selective Positive Allosteric Modulators (PAMs) of the N-Methyl-D-Aspartate (NMDA) Receptor. Journal of Medicinal Chemistry
Perszyk RE, Myers SJ, Yuan H, et al. (2020) Hodgkin-huxley-katz prize lecture: genetic and pharmacological control of glutamate receptor channel through a highly conserved gating motif. The Journal of Physiology
Zhu Z, Yi F, Epplin MP, et al. (2020) Negative allosteric modulation of GluN1/GluN3 NMDA receptors. Neuropharmacology. 108117
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