Randy Hampton

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Biochemistry, Cell Biology, Molecular Biology
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"Randy Hampton"
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Children

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Darren K. Lam research assistant 2017-2021 UCSD (Cell Biology Tree)
Danka Vuga grad student 2006 UCSD
Sonya E. Neal post-doc 2013-2018 UCSD
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Publications

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Flagg MP, Wangeline MA, Holland SR, et al. (2021) Inner-Nuclear-Membrane-Associated Degradation Employs Dfm1-Independent Retrotranslocation and Alleviates Misfolded Transmembrane-Protein Toxicity. Molecular Biology of the Cell. mbcE20110720
Wangeline MA, Hampton RY. (2020) An autonomous, but INSIG-modulated, role for the Sterol Sensing Domain in mallostery-regulated ERAD of yeast HMG-CoA reductase. The Journal of Biological Chemistry
Singh A, Vashistha N, Heck J, et al. (2020) Direct involvement of Hsp70 ATP hydrolysis in Ubr1-dependent quality control. Molecular Biology of the Cell. mbcE20080541
Neal S, Syau D, Nejatfard A, et al. (2020) HRD Complex Self-Remodeling Enables a Novel Route of Membrane Protein Retrotranslocation. Iscience. 23: 101493
Neal S, Duttke SH, Hampton RY. (2019) Assays for protein retrotranslocation in ERAD. Methods in Enzymology. 619: 1-26
Wangeline M, Hampton R. (2019) Mallostery: Ligand‐dependent Misfolding as a Strategy for Protein Regulation The Faseb Journal. 33
Wangeline MA, Hampton RY. (2018) "Mallostery"-ligand-dependent protein misfolding enables physiological regulation by ERAD. The Journal of Biological Chemistry
Neal S, Jaeger PA, Duttke SH, et al. (2018) The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins. Molecular Cell. 69: 915
Neal S, Jaeger PA, Duttke SH, et al. (2018) The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins. Molecular Cell. 69: 306-320.e4
Wangeline MA, Vashistha N, Hampton RY. (2017) Proteostatic Tactics in the Strategy of Sterol Regulation. Annual Review of Cell and Developmental Biology. 33: 467-489
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