Nga Bien-Ly, Ph.D.

Neuroscience Genentech, San Francisco, CA, United States 
Blood-brian barrier
"Nga Bien-Ly"
Mean distance: 16.79 (cluster 11)
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Xiong M, Jiang H, Serrano JR, et al. (2021) APOE immunotherapy reduces cerebral amyloid angiopathy and amyloid plaques while improving cerebrovascular function. Science Translational Medicine. 13
Liao F, Li A, Xiong M, et al. (2018) Targeting of nonlipidated, aggregated apoE with antibodies inhibits amyloid accumulation. The Journal of Clinical Investigation
Zuchero YJ, Chen X, Bien-Ly N, et al. (2015) Discovery of Novel Blood-Brain Barrier Targets to Enhance Brain Uptake of Therapeutic Antibodies. Neuron
Bien-Ly N, Boswell CA, Jeet S, et al. (2015) Lack of Widespread BBB Disruption in Alzheimer's Disease Models: Focus on Therapeutic Antibodies. Neuron. 88: 289-97
Huntley MA, Bien-Ly N, Daneman R, et al. (2014) Dissecting gene expression at the blood-brain barrier. Frontiers in Neuroscience. 8: 355
Bien-Ly N, Watts RJ. (2014) The blood-brain barrier's gut check. Science Translational Medicine. 6: 263fs46
Yu YJ, Atwal JK, Zhang Y, et al. (2014) Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates. Science Translational Medicine. 6: 261ra154
Knoferle J, Yoon SY, Walker D, et al. (2014) Apolipoprotein E4 produced in GABAergic interneurons causes learning and memory deficits in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14069-78
Bien-Ly N, Yu YJ, Bumbaca D, et al. (2014) Transferrin receptor (TfR) trafficking determines brain uptake of TfR antibody affinity variants. The Journal of Experimental Medicine. 211: 233-44
Vossel KA, Bien-Ly N, Bernardo A, et al. (2013) ApoE and TDP-43 neuropathology in two siblings with familial FTLD-motor neuron disease. Neurocase. 19: 295-301
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