Shu-ou Shan
Affiliations: | California Institute of Technology, Pasadena, CA |
Area:
Macromolecular machines; protein sorting and localization; molecular recognition and regulation by novel GTPases; protein and nucleic acid structure and functionWebsite:
http://www.cce.caltech.edu/faculty/shan/index.htmlGoogle:
"Shu-ou Shan"Mean distance: 8.16 | S | N | B | C | P |
Parents
Sign in to add mentor| Daniel Herschlag | grad student | 2000 | Stanford | |
| (Part I. Energetic analysis of hydrogen bonds in model systems: Implications for enzymatic catalysis. Part II. Probing the role of metal ions in catalysis by the Tetrahymena group I ribozyme.) | ||||
| Peter Walter | post-doc | 2005 | UCSF | |
Children
Sign in to add trainee| Tony Z Jia | research assistant | 2008-2009 | Caltech |
| Xin Zhang | grad student | Scripps Institute | |
| Peera Jaru-Ampornpan | grad student | 2011 | Caltech |
| Thang Xuan Nguyen | grad student | 2013 | Caltech |
| Kuang Shen | grad student | 2013 | Caltech |
| David Akopian | grad student | 2014 | Caltech |
| Aileen Renia Ariosa | grad student | 2014 | Caltech |
| Michael Evan Rome | grad student | 2014 | Caltech |
| Meera Rao | grad student | 2016 | Caltech |
| Un Seng Chio | grad student | 2019 | Caltech |
| Yu-Hsien Hwang Fu | grad student | 2019 | Caltech |
| Shuai Wang | grad student | 2013-2019 | Caltech (Neurotree) |
| Ishu Saraogi | post-doc | Caltech |
BETA: Related publications
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Publications
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| Lentzsch AM, Yudin D, Gamerdinger M, et al. (2024) NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature |
| Cho H, Liu Y, Chung S, et al. (2024) Dynamic stability of Sgt2 enables selective and privileged client handover in a chaperone triad. Nature Communications. 15: 134 |
| Gupta A, Lentzsch AM, Siegel A, et al. (2023) Dodecamer assembly of a metazoan AAA chaperone couples substrate extraction to refolding. Science Advances. 9: eadf5336 |
| Shan SO. (2023) Role of Hsp70 in Post-Translational Protein Targeting: Tail-Anchored Membrane Proteins and Beyond. International Journal of Molecular Sciences. 24 |
| Yang CI, Zhu Z, Jones JJ, et al. (2022) System-wide analyses reveal essential roles of N-terminal protein modification in bacterial membrane integrity. Iscience. 25: 104756 |
| Zhu Z, Wang S, Shan SO. (2022) Ribosome profiling reveals multiple roles of SecA in cotranslational protein export. Nature Communications. 13: 3393 |
| Yang CI, Kim J, Shan SO. (2022) Ribosome-nascent Chain Interaction Regulates N-terminal Protein Modification. Journal of Molecular Biology. 434: 167535 |
| Jomaa A, Gamerdinger M, Hsieh HH, et al. (2022) Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting. Science (New York, N.Y.). 375: 839-844 |
| Hsieh HH, Shan SO. (2021) Fidelity of Cotranslational Protein Targeting to the Endoplasmic Reticulum. International Journal of Molecular Sciences. 23 |
| Chio US, Liu Y, Chung S, et al. (2021) Subunit cooperation in the Get1/2 receptor promotes tail-anchored membrane protein insertion. The Journal of Cell Biology. 220 |