Cynthia Wolberger

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
ubiquitination and acetylation, transcription, x-ray crystallography, cryo-EM, biophysical methods
Website:
http://wolbergerlab.org
Google:
"Cynthia Wolberger"
Bio:

https://en.wikipedia.org/wiki/Cynthia_Wolberger

Mean distance: 7.91
 
SNBCP

Parents

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Stephen C. Harrison grad student 1988 Harvard
 (The structure of a 434 Cro-DNA complex)
Mark Ptashne grad student 1988 Harvard
Carl O. Pabo post-doc Johns Hopkins
Robert M. Stroud post-doc 1987-1989 UCSF
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Publications

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Zhao F, Hicks CW, Wolberger C. (2023) Mechanism of histone H2B monoubiquitination by Bre1. Nature Structural & Molecular Biology
Zhao F, Hicks CW, Wolberger C. (2023) Mechanism of histone H2B monoubiquitination by Bre1. Biorxiv : the Preprint Server For Biology
Rahman S, Hoffmann NA, Worden EJ, et al. (2022) Multistate structures of the MLL1-WRAD complex bound to H2B-ubiquitinated nucleosome. Proceedings of the National Academy of Sciences of the United States of America. 119: e2205691119
Lombardi PM, Haile S, Rusanov T, et al. (2021) The ASCC2 CUE domain in the ALKBH3-ASCC DNA repair complex recognizes adjacent ubiquitins in K63-linked polyubiquitin. The Journal of Biological Chemistry. 101545
Wolberger C. (2021) How structural biology transformed studies of transcription regulation. The Journal of Biological Chemistry. 100741
Que LT, Morrow ME, Wolberger C. (2020) Comparison of cross-regulation by different OTUB1-E2 complexes. Biochemistry
Worden EJ, Zhang X, Wolberger C. (2020) Structural basis for COMPASS recognition of an H2B-ubiquitinated nucleosome. Elife. 9
Worden EJ, Zhang X, Wolberger C. (2020) Author response: Structural basis for COMPASS recognition of an H2B-ubiquitinated nucleosome Elife
Worden EJ, Wolberger C. (2019) Activation and regulation of H2B-Ubiquitin-dependent histone methyltransferases. Current Opinion in Structural Biology. 59: 98-106
Morgan M, Jbara M, Brik A, et al. (2019) Semisynthesis of ubiquitinated histone H2B with a native or nonhydrolyzable linkage. Methods in Enzymology. 618: 1-27
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