Frederick R. Maxfield

Biochemistry Weill Cornell Medical College, New York, NY, United States 
"Frederick Maxfield"
Mean distance: 16.02 (cluster 32)
Cross-listing: Cell Biology Tree - Chemistry Tree

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Davidson J, Molitor E, Moores S, et al. (2019) 2-Hydroxypropyl-β-cyclodextrin is the active component in a triple combination formulation for treatment of Niemann-Pick C1 disease. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids
Solé-Domènech S, Rojas AV, Maisuradze GG, et al. (2018) Lysosomal enzyme tripeptidyl peptidase 1 destabilizes fibrillar Aβ by multiple endoproteolytic cleavages within the β-sheet domain. Proceedings of the National Academy of Sciences of the United States of America
Karuppagounder SS, Alim I, Khim SJ, et al. (2016) Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models. Science Translational Medicine. 8: 328ra29
Iaea DB, Gale SE, Bielska AA, et al. (2015) A novel intrinsically fluorescent probe for study of uptake and trafficking of 25-hydroxycholesterol. Journal of Lipid Research
Haka AS, Singh RK, Grosheva I, et al. (2015) Monocyte-Derived Dendritic Cells Upregulate Extracellular Catabolism of Aggregated Low-Density Lipoprotein on Maturation, Leading to Foam Cell Formation. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 2092-103
Iaea DB, Dikiy I, Kiburu I, et al. (2015) STARD4 Membrane Interactions and Sterol Binding. Biochemistry. 54: 4623-36
Praggastis M, Tortelli B, Zhang J, et al. (2015) A Murine Niemann-Pick C1 I1061T Knock-In Model Recapitulates the Pathological Features of the Most Prevalent Human Disease Allele. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8091-106
Iaea DB, Maxfield FR. (2015) Cholesterol trafficking and distribution. Essays in Biochemistry. 57: 43-55
Patel JZ, Nevalainen TJ, Savinainen JR, et al. (2015) Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors. Chemmedchem. 10: 253-65
Iaea DB, Mao S, Maxfield FR. (2015) Steroidogenic acute regulatory protein-related lipid transfer (START) proteins in non-vesicular cholesterol transport Cholesterol Transporters of the Start Domain Protein Family in Health and Disease: Start Proteins-Structure and Function. 173-188
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