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Ira Pastan

Affiliations: 
National Institutes of Health, Bethesda, MD 
Area:
Molecular Biology
Website:
http://ccr.nci.nih.gov/staff/staff.asp?profileid=5782
Google:
"Ira Pastan"
Mean distance: 14.27 (cluster 32)
 
SNBCP
Cross-listing: Chemistry Tree

Parents

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Earl R. Stadtman post-doc 1959-1961 NIH

Children

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John A. Hanover post-doc NIH (NCI) (FlyTree)
Frederick R. Maxfield post-doc NIH
Robert J. Lefkowitz post-doc 1968-1970 NIH
Harold Elliot Varmus research scientist 1968-1970 NIH (DevTree)
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Publications

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Kreitman RJ, Tallman MS, Robak T, et al. (2018) Minimal residual hairy cell leukemia eradication with moxetumomab pasudotox: phase I results and long-term follow-up. Blood
Liu XF, Xiang L, Zhou Q, et al. (2016) Actinomycin D enhances killing of cancer cells by immunotoxin RG7787 through activation of the extrinsic pathway of apoptosis. Proceedings of the National Academy of Sciences of the United States of America
Antignani A, Mathews Griner L, Guha R, et al. (2016) Chemical Screens Identify Drugs that Enhance or Mitigate Cellular Responses to Antibody-Toxin Fusion Proteins. Plos One. 11: e0161415
Kaplan G, Lee F, Onda M, et al. (2016) Protection of the Furin Cleavage Site in Low-Toxicity Immunotoxins Based on Pseudomonas Exotoxin A. Toxins. 8
Awuah P, Bera TK, Folivi M, et al. (2016) Reduced Shedding of Surface Mesothelin Improves Efficacy of Mesothelin Targeting Recombinant Immunotoxins. Molecular Cancer Therapeutics
Liang X, Schnaper HW, Matsusaka T, et al. (2016) Anti-TGF-β Antibody, 1D11, Ameliorates Glomerular Fibrosis in Mouse Models after the Onset of Proteinuria. Plos One. 11: e0155534
Guha R, Mathews Griner LA, Keller JM, et al. (2016) Ranking Differential Drug Activities from Dose-Response Synthetic Lethality Screens. Journal of Biomolecular Screening
Bao X, Chandramohan V, Reynolds RP, et al. (2016) Preclinical toxicity evaluation of a novel immunotoxin, D2C7-(scdsFv)-PE38KDEL, administered via intracerebral convection-enhanced delivery in rats. Investigational New Drugs
Ali-Rahmani F, FitzGerald DJ, Martin S, et al. (2015) Anticancer Effects of Mesothelin-targeted Immunotoxin Therapy are Regulated by Tyrosine Kinase DDR1. Cancer Research
Kreitman RJ, Pastan I. (2015) Immunoconjugates in the management of hairy cell leukemia. Best Practice & Research. Clinical Haematology. 28: 236-45
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