Jason P. Covy

Affiliations: 
Stanford University, Palo Alto, CA 
Area:
Transynaptic Signaling, Transmembrane Proteins, Neuordegeneration, Neuropharmaclogy, Neuroscience, Synaptic Plasticity
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"Jason Covy"
Mean distance: 14.63 (cluster 32)
 
SNBCP

Parents

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Benoit I. Giasson grad student 2004-2010 Penn
 (The pathological and biochemical characterization of leucine-rich repeat kinase 2 in Parkinson's disease.)
Thomas C. Sudhof post-doc 2011- Stanford
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Publications

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Patzke C, Han Y, Covy J, et al. (2015) Analysis of conditional heterozygous STXBP1 mutations in human neurons. The Journal of Clinical Investigation. 125: 3560-71
Anderson GR, Aoto J, Tabuchi K, et al. (2015) β-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling. Cell. 162: 593-606
Bailey RM, Covy JP, Melrose HL, et al. (2013) LRRK2 phosphorylates novel tau epitopes and promotes tauopathy. Acta Neuropathologica. 126: 809-27
Zhang Y, Pak C, Han Y, et al. (2013) Rapid single-step induction of functional neurons from human pluripotent stem cells. Neuron. 78: 785-98
Covy JP, Waxman EA, Giasson BI. (2012) Characterization of cellular protective effects of ATP13A2/PARK9 expression and alterations resulting from pathogenic mutants. Journal of Neuroscience Research. 90: 2306-16
Emmer KL, Covy JP, Giasson BI. (2012) Studies of protein aggregation in A53T α-synuclein transgenic, Tg2576 transgenic, and P246L presenilin-1 knock-in cross bred mice. Neuroscience Letters. 507: 137-42
Emmer KL, Waxman EA, Covy JP, et al. (2011) E46K human alpha-synuclein transgenic mice develop Lewy-like and tau pathology associated with age-dependent, detrimental motor impairment. The Journal of Biological Chemistry. 286: 35104-18
Covy JP, Giasson BI. (2011) α-Synuclein, leucine-rich repeat kinase-2, and manganese in the pathogenesis of Parkinson disease. Neurotoxicology. 32: 622-9
Covy JP, Giasson BI. (2010) The G2019S pathogenic mutation disrupts sensitivity of leucine-rich repeat kinase 2 to manganese kinase inhibition. Journal of Neurochemistry. 115: 36-46
Waxman EA, Covy JP, Bukh I, et al. (2009) Leucine-rich repeat kinase 2 expression leads to aggresome formation that is not associated with alpha-synuclein inclusions. Journal of Neuropathology and Experimental Neurology. 68: 785-96
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