Alan L. Goldin, M.D., Ph.D.

Affiliations: 
Microbiology & Molecular Genetics University of California, Irvine, Irvine, CA 
Area:
Sodium channels, epilepsy
Website:
http://www.faculty.uci.edu/profile.cfm?faculty_id=2308&name=Alan%20L.%20Goldin
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"Alan Goldin"
Bio:

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Mean distance: 13.83 (cluster 11)
 
SNBCP
Cross-listing: Chemistry Tree

Children

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Eric Velazquez grad student UC Irvine
Jay G. Spampanato grad student 2004 UC Irvine
Wei Zhou grad student 2004 UC Irvine
Arthur J. Barela grad student 2008 UC Irvine
Annie Lee grad student 2008 UC Irvine
Hai M. Nguyen grad student 2009 UC Irvine
Karoni Dutt grad student 2010 UC Irvine
Brian S. Tanaka grad student 2006-2014 UC Irvine
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Publications

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Wong JC, Grieco SF, Dutt K, et al. (2021) Autistic-like behavior, spontaneous seizures, and increased neuronal excitability in a Scn8a mouse model. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Pugsley MK, Yong SL, Goldin AL, et al. (2019) Molecular charge associated with antiarrhythmic actions in a series of amino-2-cyclohexyl ester derivatives. European Journal of Pharmacology. 844: 241-252
Walker MJA, Hayes ES, Saint DA, et al. (2018) Pharmacological and toxicological activity of RSD921, a novel sodium channel blocker. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 106: 510-522
Dutton SB, Dutt K, Papale LA, et al. (2017) Early-life febrile seizures worsen adult phenotypes in Scn1a mutants. Experimental Neurology
Makinson CD, Tanaka BS, Sorokin JM, et al. (2017) Regulation of Thalamic and Cortical Network Synchrony by Scn8a. Neuron
Meisler MH, Helman G, Hammer MF, et al. (2016) SCN8A encephalopathy: Research progress and prospects. Epilepsia
Makinson CD, Dutt K, Lin F, et al. (2015) An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior. Experimental Neurology
Goldin AL, Escayg A. (2015) Complex genetic interactions in a mouse model of absence epilepsy. Epilepsy Currents / American Epilepsy Society. 15: 50-1
Coleman N, Nguyen HM, Cao Z, et al. (2015) The riluzole derivative 2-amino-6-trifluoromethylthio-benzothiazole (SKA-19), a mixed KCa2 activator and NaV blocker, is a potent novel anticonvulsant. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 12: 234-49
Makinson CD, Tanaka BS, Lamar T, et al. (2014) Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance. Neurobiology of Disease. 68: 16-25
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