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James Nicholas Sleigh

Affiliations: 
University College London, London, United Kingdom 
Area:
neuromuscular disease, motor neuron, sensory neuron, neuromuscular junction, neuropathy, Charcot-Marie-Tooth, spinal muscular atrophy
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Parents

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Kay Elizabeth Davies grad student 2009-2012 Oxford
David B. Sattelle grad student 2009-2012 Oxford
Kevin Talbot grad student 2009-2012 Oxford
Giampietro Schiavo post-doc 2014-2018 UCL Institute of Neurology, Queen Square

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Publications

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Rhymes ER, Simkin RL, Qu J, et al. (2024) Boosting BDNF in muscle rescues impaired axonal transport in a mouse model of DI-CMTC peripheral neuropathy. Neurobiology of Disease. 106501
Rhymes ER, Simkin RL, Qu J, et al. (2024) Boosting BDNF in muscle rescues impaired axonal transport in a mouse model of DI-CMTC peripheral neuropathy. Biorxiv : the Preprint Server For Biology
Sleigh JN, Villarroel-Campos D, Surana S, et al. (2023) Boosting peripheral BDNF rescues impaired in vivo axonal transport in CMT2D mice. Jci Insight
Lang Q, Schiavo G, Sleigh JN. (2023) imaging of axonal transport in peripheral nerves of rodent forelimbs. Neuronal Signaling. 7: NS20220098
Negro S, Lauria F, Stazi M, et al. (2022) Hydrogen peroxide induced by nerve injury promotes axon regeneration via connective tissue growth factor. Acta Neuropathologica Communications. 10: 189
Sleigh JN, Schiavo G. (2022) Neuroscience highlights in 2022: cytoskeletal transport. The Lancet. Neurology. 22: 25-27
Tosolini AP, Sleigh JN, Surana S, et al. (2022) BDNF-dependent modulation of axonal transport is selectively impaired in ALS. Acta Neuropathologica Communications. 10: 121
Sahoo PK, Willis DE, Sleigh JN. (2022) Editorial: Pathways and Processes Underpinning Axonal Biology and Pathobiology. Frontiers in Molecular Neuroscience. 15: 883244
Vargas JNS, Sleigh JN, Schiavo G. (2022) Coupling axonal mRNA transport and local translation to organelle maintenance and function. Current Opinion in Cell Biology. 74: 97-103
Tosolini AP, Villarroel-Campos D, Schiavo G, et al. (2021) Expanding the Toolkit for In Vivo Imaging of Axonal Transport. Journal of Visualized Experiments : Jove
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