Kevin Talbot, M.D., D.Phil.

Affiliations: 
Physiology, Anatomy and Genetics University of Oxford, Oxford, United Kingdom 
Area:
Motor Neuron Degeneration
Website:
http://www.dpag.ox.ac.uk/academic_staff/kevin_talbot
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"Kevin Talbot"
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Children

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Jennifer C. Schymick grad student 2005-2009 Oxford
William W. Motley grad student 2006-2010 Oxford
James Nicholas Sleigh grad student 2009-2012 Oxford
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Publications

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Oprişoreanu AM, Smith HL, Arya S, et al. (2019) Interaction of Axonal Chondrolectin with Collagen XIXa1 Is Necessary for Precise Neuromuscular Junction Formation. Cell Reports. 29: 1082-1098.e10
Williamson MG, Finelli MJ, Sleigh JN, et al. (2019) Neuronal over-expression of Oxr1 is protective against ALS-associated mutant TDP-43 mislocalisation in motor neurons and neuromuscular defects in vivo. Human Molecular Genetics
Gordon D, Dafinca R, Scaber J, et al. (2018) Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor dysfunction. Neurobiology of Disease
Nicolas A, Kenna KP, Renton AE, et al. (2018) Genome-wide Analyses Identify KIF5A as a Novel ALS Gene. Neuron. 97: 1268-1283.e6
Groen EJN, Talbot K, Gillingwater TH. (2018) Advances in therapy for spinal muscular atrophy: promises and challenges. Nature Reviews. Neurology
Bowerman M, Becker CG, Yáñez-Muñoz RJ, et al. (2017) Therapeutic strategies for spinal muscular atrophy: SMN and beyond. Disease Models & Mechanisms. 10: 943-954
Sleigh JN, Dawes JM, West SJ, et al. (2017) Trk receptor signaling and sensory neuron fate are perturbed in human neuropathy caused by Gars mutations. Proceedings of the National Academy of Sciences of the United States of America
Hammond SM, Hazell G, Shabanpoor F, et al. (2016) Systemic peptide-mediated oligonucleotide therapy improves long-term survival in spinal muscular atrophy. Proceedings of the National Academy of Sciences of the United States of America
McGeachan AJ, Hobson EV, Al-Chalabi A, et al. (2016) A multicentre evaluation of oropharyngeal secretion management practices in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-9
Kenna KP, van Doormaal PT, Dekker AM, et al. (2016) NEK1 variants confer susceptibility to amyotrophic lateral sclerosis. Nature Genetics
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