Xinhong Chen
Affiliations: | California Institute of Technology, Pasadena, CA |
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Parents
Sign in to add mentor| Lei Xue | research assistant | 2013-2017 | Tongji University | |
| (Undergraduate Researcher) | ||||
| Kay M. Tye | research assistant | 2016-2017 | MIT | |
| (Visiting Student / Full-time Undergraduate Researcher) | ||||
| Viviana Gradinaru | grad student | 2018- | Caltech | |
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Publications
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| Ding X, Chen X, Sullivan EE, et al. (2024) Fast, accurate ranking of engineered proteins by target binding propensity using structure modeling. Molecular Therapy : the Journal of the American Society of Gene Therapy |
| Coughlin GM, Borsos M, Appling N, et al. (2023) Spatial genomics of AAVs reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo. Biorxiv : the Preprint Server For Biology |
| Chuapoco MR, Flytzanis NC, Goeden N, et al. (2023) Adeno-associated viral vectors for functional intravenous gene transfer throughout the non-human primate brain. Nature Nanotechnology |
| Campos LJ, Arokiaraj CM, Chuapoco MR, et al. (2023) Advances in AAV technology for delivering genetically encoded cargo to the nonhuman primate nervous system. Current Research in Neurobiology. 4: 100086 |
| Chen X, Wolfe DA, Bindu DS, et al. (2023) Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates. Nature Communications. 14: 3345 |
| Shay TF, Sullivan EE, Ding X, et al. (2023) Primate-conserved carbonic anhydrase IV and murine-restricted LY6C1 enable blood-brain barrier crossing by engineered viral vectors. Science Advances. 9: eadg6618 |
| Chuapoco M, Flytzanis N, Goeden N, et al. (2023) Intravenous functional gene transfer throughout the brain of non-human primates using AAV. Research Square |
| Chen X, Wolfe DA, Sivadasan Bindu D, et al. (2023) Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates. Biorxiv : the Preprint Server For Biology |
| Jang MJ, Coughlin GM, Jackson CR, et al. (2023) Spatial transcriptomics for profiling the tropism of viral vectors in tissues. Nature Biotechnology |
| Chen X, Ravindra Kumar S, Adams CD, et al. (2022) Engineered AAVs for non-invasive gene delivery to rodent and non-human primate nervous systems. Neuron |