Marcela V. Maus, Ph.D. - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 

208 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Choi BD, Gerstner ER, Frigault MJ, Leick MB, Mount CW, Balaj L, Nikiforow S, Carter BS, Curry WT, Gallagher K, Maus MV. Intraventricular CARv3-TEAM-E T Cells in Recurrent Glioblastoma. The New England Journal of Medicine. PMID 38477966 DOI: 10.1056/NEJMoa2314390  0.524
2024 Lee WH, Graham CE, Wiggin HR, Nolan HK, Graham KJ, Korell F, Leick MB, Barselau AL, Emmanuel-Alejandro E, Trailor MA, Gildea JM, Preffer F, Frigault MJ, Maus MV, Gallagher KME. Optimization of a flow cytometry test for routine monitoring of B cell maturation antigen targeted CAR in peripheral blood. Cytometry. Part B, Clinical Cytometry. PMID 38418432 DOI: 10.1002/cyto.b.22165  0.548
2024 Wehrli M, Guinn S, Birocchi F, Kuo A, Sun Y, Larson RC, Almazan AJ, Scarfò I, Bouffard AA, Bailey SR, Anekal PV, Montero Lopis P, Nieman LT, Song Y, Xu KH, ... ... Maus MV, et al. Mesothelin CAR T-cells secreting anti-FAP/anti-CD3 molecules efficiently target pancreatic adenocarcinoma and its stroma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 38393682 DOI: 10.1158/1078-0432.CCR-23-3841  0.591
2024 Kembuan GJ, Kim JY, Maus MV, Jan M. Targeting solid tumor antigens with chimeric receptors: cancer biology meets synthetic immunology. Trends in Cancer. PMID 38355356 DOI: 10.1016/j.trecan.2024.01.003  0.495
2024 Haradhvala NJ, Maus MV. Understanding Mechanisms of Response to CAR T-cell Therapy through Single-Cell Sequencing: Insights and Challenges. Blood Cancer Discovery. 5: 86-89. PMID 38324393 DOI: 10.1158/2643-3230.BCD-23-0212  0.5
2024 Levine BL, Pasquini MC, Connolly JE, Porter DL, Gustafson MP, Boelens JJ, Horwitz EM, Grupp SA, Maus MV, Locke FL, Ciceri F, Ruggeri A, Snowden J, Heslop HE, Mackall CL, et al. Unanswered questions following reports of secondary malignancies after CAR-T cell therapy. Nature Medicine. PMID 38195751 DOI: 10.1038/s41591-023-02767-w  0.611
2023 Kann MC, Schneider EM, Almazan AJ, Lane IC, Bouffard AA, Supper VM, Takei HN, Tepper A, Leick MB, Larson RC, Ebert BL, Maus MV, Jan M. Chemical genetic control of cytokine signaling in CAR-T cells using lenalidomide-controlled membrane-bound degradable IL-7. Leukemia. PMID 38123696 DOI: 10.1038/s41375-023-02113-6  0.487
2023 Boucher JC, Shrestha B, Vishwasrao P, Leick M, Cervantes EV, Ghafoor T, Reid K, Spitler K, Yu B, Betts BC, Guevara-Patino JA, Maus MV, Davila ML. Bispecific CD33/CD123 targeted chimeric antigen receptor T cells for the treatment of acute myeloid leukemia. Molecular Therapy Oncolytics. 31: 100751. PMID 38075241 DOI: 10.1016/j.omto.2023.100751  0.417
2023 Ramos A, Koch CE, Liu-Lupo Y, Hellinger RD, Kyung T, Abbott KL, Fröse J, Goulet D, Gordon KS, Eidell KP, Leclerc P, Whittaker CA, Larson RC, Muscato AJ, Yates KB, ... ... Maus MV, et al. Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening. Nature Communications. 14: 8048. PMID 38052854 DOI: 10.1038/s41467-023-43790-2  0.53
2023 Lane IC, Kembuan G, Carreiro J, Kann MC, Lin W, Bouffard AA, Kreuzer J, Morris R, Schneider EM, Kim JY, Zou C, Salas-Benito D, Gasser JA, Leick MB, Słabicki M, ... ... Maus MV, et al. Genetic retargeting of E3 ligases to enhance CAR T cell therapy. Cell Chemical Biology. PMID 37989314 DOI: 10.1016/j.chembiol.2023.10.024  0.47
2023 Larson RC, Kann MC, Graham C, Mount CW, Castano AP, Lee WH, Bouffard AA, Takei HN, Almazan AJ, Scarfó I, Berger TR, Schmidts A, Frigault MJ, Gallagher KME, Maus MV. Anti-TACI single and dual-targeting CAR T cells overcome BCMA antigen loss in multiple myeloma. Nature Communications. 14: 7509. PMID 37980341 DOI: 10.1038/s41467-023-43416-7  0.528
2023 Lareau CA, Yin Y, Maurer K, Sandor KD, Daniel B, Yagnik G, Peña J, Crawford JC, Spanjaart AM, Gutierrez JC, Haradhvala NJ, Riberdy JM, Abay T, Stickels RR, Verboon JM, ... ... Maus MV, et al. Latent human herpesvirus 6 is reactivated in CAR T cells. Nature. PMID 37938768 DOI: 10.1038/s41586-023-06704-2  0.527
2023 Ruella M, Korell F, Porazzi P, Maus MV. Mechanisms of resistance to chimeric antigen receptor-T cells in haematological malignancies. Nature Reviews. Drug Discovery. 22: 976-995. PMID 37907724 DOI: 10.1038/s41573-023-00807-1  0.517
2023 Elsallab M, Maus MV. Expanding access to CAR T cell therapies through local manufacturing. Nature Biotechnology. 41: 1698-1708. PMID 37884746 DOI: 10.1038/s41587-023-01981-8  0.405
2023 Singh N, Maus MV. Synthetic manipulation of the cancer-immunity cycle: CAR-T cell therapy. Immunity. 56: 2296-2310. PMID 37820585 DOI: 10.1016/j.immuni.2023.09.010  0.493
2023 Kronig MN, Wehrli M, Salas-Benito D, Maus MV. "Hurdles race for CAR T-cell therapy in digestive tract cancer". Immunological Reviews. 320: 100-119. PMID 37694970 DOI: 10.1111/imr.13273  0.441
2023 Lin Y, Raje NS, Berdeja JG, Siegel DS, Jagannath S, Madduri D, Liedtke M, Rosenblatt J, Maus MV, Massaro M, Petrocca F, Yeri A, Finney O, Caia A, Yang Z, et al. Idecabtagene vicleucel for relapsed and refractory multiple myeloma: post hoc 18-month follow-up of a phase 1 trial. Nature Medicine. PMID 37592106 DOI: 10.1038/s41591-023-02496-0  0.412
2023 Curran KJ, Nikiforow S, Bachier C, Hsu YM, Maloney DG, Maus MV, McCarthy PL, Porter DL, Shi PA, Shpall EJ, William B, Wacker K, Warkentin P, Heslop HE. Robust Quality Infrastructure is Key to Safe and Effective Delivery of Immune Effector Cells: How FACT-Finding Can Help. Blood Advances. PMID 37467016 DOI: 10.1182/bloodadvances.2023010401  0.337
2023 Maus MV. Signatures of dysfunctional CAR T cells. Blood. 141: 3127-3129. PMID 37383003 DOI: 10.1182/blood.2023020935  0.517
2023 Pourzia AL, Olson ML, Bailey SR, Boroughs AC, Aryal A, Ryan J, Maus MV, Letai A. Quantifying requirements for mitochondrial apoptosis in CAR T killing of cancer cells. Cell Death & Disease. 14: 267. PMID 37055388 DOI: 10.1038/s41419-023-05727-x  0.467
2023 DeFilipp Z, Maus MV. Linking the microbiome to CAR-T cell responses. Nature Medicine. PMID 36973411 DOI: 10.1038/s41591-023-02272-0  0.489
2023 Hines MR, Knight TE, McNerney KO, Leick MB, Jain T, Ahmed S, Frigault MJ, Hill JA, Jain MD, Johnson WT, Lin Y, Mahadeo KM, Maron GM, Marsh RA, Neelapu SS, ... ... Maus MV, et al. Immune Effector Cell associated Hemophagocytic Lymphohistiocytosis-like Syndrome (IEC-HS). Transplantation and Cellular Therapy. PMID 36906275 DOI: 10.1016/j.jtct.2023.03.006  0.511
2023 Leick MB, Maus MV. Multiomics STEP up in correlative analysis of response to CAR T cells. Nature Reviews. Clinical Oncology. PMID 36792726 DOI: 10.1038/s41571-023-00742-5  0.439
2022 Dupouy S, Marchiq I, Derippe T, Almena-Carrasco M, Jozwik A, Fouliard S, Adimy Y, Geronimi J, Graham C, Jain N, Maus MV, Mohty M, Boissel N, Teshima T, Kato K, et al. Clinical Pharmacology and Determinants of Response to UCART19, an Allogeneic Anti-CD19 CAR-T Cell Product, in Adult B-cell Acute Lymphoblastic Leukemia. Cancer Research Communications. 2: 1520-1531. PMID 36970059 DOI: 10.1158/2767-9764.CRC-22-0175  0.513
2022 Schmidts A, Srivastava AA, Ramapriyan R, Bailey SR, Bouffard AA, Cahill DP, Carter BS, Curry WT, Dunn GP, Frigault MJ, Gerstner ER, Ghannam JY, Kann MC, Larson RC, Leick MB, ... ... Maus MV, et al. Tandem chimeric antigen receptor (CAR) T cells targeting EGFRvIII and IL-13Rα2 are effective against heterogeneous glioblastoma. Neuro-Oncology Advances. 5: vdac185. PMID 36751672 DOI: 10.1093/noajnl/vdac185  0.534
2022 Bailey SR, Berger TR, Graham C, Larson RC, Maus MV. Four challenges to CAR T cells breaking the glass ceiling. European Journal of Immunology. e2250039. PMID 36585889 DOI: 10.1002/eji.202250039  0.553
2022 Hagel KR, Arafeh R, Gang S, Arnoff TE, Larson RC, Doench JG, Mathewson ND, Wucherpfennig KW, Maus MV, Hahn WC. Systematic interrogation of tumor cell resistance to CAR T cell therapy in pancreatic cancer. Cancer Research. PMID 36548402 DOI: 10.1158/0008-5472.CAN-22-2245  0.544
2022 Irvine DJ, Maus MV, Mooney DJ, Wong WW. The future of engineered immune cell therapies. Science (New York, N.Y.). 378: 853-858. PMID 36423279 DOI: 10.1126/science.abq6990  0.35
2022 Benjamin R, Jain N, Maus MV, Boissel N, Graham C, Jozwik A, Yallop D, Konopleva M, Frigault MJ, Teshima T, Kato K, Boucaud F, Balandraud S, Gianella-Borradori A, Binlich F, et al. UCART19, a first-in-class allogeneic anti-CD19 chimeric antigen receptor T-cell therapy for adults with relapsed or refractory B-cell acute lymphoblastic leukaemia (CALM): a phase 1, dose-escalation trial. The Lancet. Haematology. PMID 36228643 DOI: 10.1016/S2352-3026(22)00245-9  0.477
2022 Gaballa MR, Maus MV. High antigen density of BCMA: friend or foe to CAR T cells? Journal For Immunotherapy of Cancer. 10. PMID 36137650 DOI: 10.1136/jitc-2022-005822  0.47
2022 Haradhvala NJ, Leick MB, Maurer K, Gohil SH, Larson RC, Yao N, Gallagher KME, Katsis K, Frigault MJ, Southard J, Li S, Kann MC, Silva H, Jan M, Rhrissorrakrai K, ... ... Maus MV, et al. Distinct cellular dynamics associated with response to CAR-T therapy for refractory B cell lymphoma. Nature Medicine. PMID 36097221 DOI: 10.1038/s41591-022-01959-0  0.584
2022 Graham CE, Maus MV. CAR T cells Contend with Myeloma in the Bone Marrow Microenvironment. Blood Cancer Discovery. PMID 36026510 DOI: 10.1158/2643-3230.BCD-22-0126  0.458
2022 Korell F, Berger TR, Maus MV. Understanding CAR T cell-tumor interactions: Paving the way for successful clinical outcomes. Med (New York, N.Y.). 3: 538-564. PMID 35963235 DOI: 10.1016/j.medj.2022.05.001  0.532
2022 Jing R, Scarfo I, Najia MA, Lummertz da Rocha E, Han A, Sanborn M, Bingham T, Kubaczka C, Jha DK, Falchetti M, Schlaeger TM, North TE, Maus MV, Daley GQ. EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activity. Cell Stem Cell. 29: 1181-1196.e6. PMID 35931029 DOI: 10.1016/j.stem.2022.06.014  0.56
2022 Maus MV. Safety of genetically modified T cells. Blood. 140: 1-2. PMID 35797018 DOI: 10.1182/blood.2022016334  0.398
2022 Leick MB, Silva H, Scarfò I, Larson R, Choi BD, Bouffard AA, Gallagher K, Schmidts A, Bailey SR, Kann MC, Jan M, Wehrli M, Grauwet K, Horick N, Frigault MJ, ... Maus MV, et al. Non-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemia. Cancer Cell. PMID 35452603 DOI: 10.1016/j.ccell.2022.04.001  0.467
2022 Larson RC, Kann MC, Bailey SR, Haradhvala NJ, Llopis PM, Bouffard AA, Scarfó I, Leick MB, Grauwet K, Berger TR, Stewart K, Anekal PV, Jan M, Joung J, Schmidts A, ... ... Maus MV, et al. CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours. Nature. 604: 563-570. PMID 35418687 DOI: 10.1038/s41586-022-04585-5  0.538
2022 Gill SI, Frey NV, Hexner E, Metzger S, O'Brien M, Hwang WT, Brogdon JL, Davis MM, Fraietta JA, Gaymon A, Gladney WL, Lacey SF, Lamontagne A, Mato AR, Maus MV, et al. Anti-CD19 CAR T Cells in Combination with Ibrutinib for the Treatment of Chronic Lymphocytic Leukemia. Blood Advances. PMID 35349631 DOI: 10.1182/bloodadvances.2022007317  0.514
2022 Joung J, Kirchgatterer PC, Singh A, Cho JH, Nety SP, Larson RC, Macrae RK, Deasy R, Tseng YY, Maus MV, Zhang F. CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity. Nature Communications. 13: 1606. PMID 35338135 DOI: 10.1038/s41467-022-29205-8  0.434
2022 Maus MV. A decade of CAR T cell evolution. Nature Cancer. 3: 270-271. PMID 35288717 DOI: 10.1038/s43018-022-00347-4  0.522
2022 Gallagher KME, Leick MB, Larson RC, Berger TR, Katsis K, Yam JY, Maus MV. Differential T cell immunity to SARS-CoV-2 in mRNA-1273 and BNT162b2 vaccinated individuals. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 35278306 DOI: 10.1093/cid/ciac201  0.332
2022 How J, Gallagher KME, Liu Y, Katsis K, Elder EL, Larson RC, Leick MB, Neuberg D, Maus MV, Hobbs GS. Antibody and T-cell responses to SARS-CoV-2 vaccination in myeloproliferative neoplasm patients. Leukemia. PMID 35217807 DOI: 10.1038/s41375-022-01533-0  0.361
2022 Frigault MJ, Dietrich J, Gallagher KME, Roschewski MJ, Jordan JT, Forst D, Plotkin SR, Cook D, Casey KS, Lindell KA, DePinho GD, Katsis K, Elder EL, Leick M, Choi BD, ... ... Maus MV, et al. Safety and Efficacy of Tisagenlecleucel in Primary CNS Lymphoma: A phase I/II clinical trial. Blood. PMID 35167655 DOI: 10.1182/blood.2021014738  0.394
2022 Haydu JE, Maron JS, Redd RA, Gallagher KME, Fischinger S, Barnes JA, Hochberg EP, Johnson PC, Takvorian RW, Katsis K, Portman D, Ruiters J, Sechio S, Devlin MC, Regan C, ... ... Maus MV, et al. Humoral and cellular immunogenicity of SARS-CoV-2 vaccines in chronic lymphocytic leukemia: a prospective cohort study. Blood Advances. PMID 35073571 DOI: 10.1182/bloodadvances.2021006627  0.316
2022 Wehrli M, Gallagher K, Chen YB, Leick MB, McAfee SL, El-Jawahri AR, DeFilipp Z, Horick N, O'Donnell P, Spitzer T, Dey B, Cook D, Trailor M, Lindell K, Maus MV, et al. Single-center experience using anakinra for steroid-refractory immune effector cell-associated neurotoxicity syndrome (ICANS). Journal For Immunotherapy of Cancer. 10. PMID 34996813 DOI: 10.1136/jitc-2021-003847  0.384
2021 Bailey SR, Vatsa S, Larson RC, Bouffard AA, Scarfo I, Kann MC, Berger TR, Leick MB, Wehrli M, Schmidts A, Silva H, Lindell KA, Demato A, Gallagher KM, Frigault MJ, ... Maus MV, et al. Blockade or deletion of IFNg reduces macrophage activation without compromising CAR-T function in hematologic malignancies. Blood Cancer Discovery. PMID 35015685 DOI: 10.1158/2643-3230.BCD-21-0181  0.515
2021 Villalba JA, Maus MV, Frigault MJ, Zaffini R, Gandhi RT, Rosenberg ES, Siedner MJ. False-positive HIV testing in patients receiving lentivirus-based chimeric antigen receptor T-cell therapy: A case report, review of the literature and proposed recommendations. The Journal of Infectious Diseases. PMID 34927686 DOI: 10.1093/infdis/jiab605  0.357
2021 Yan C, Yang Q, Zhang S, Millar DG, Alpert EJ, Do D, Veloso A, Brunson DC, Drapkin BJ, Stanzione M, Scarfò I, Moore JC, Iyer S, Qin Q, Wei Y, ... ... Maus MV, et al. Single-cell imaging of T cell immunotherapy responses in vivo. The Journal of Experimental Medicine. 218. PMID 34415995 DOI: 10.1084/jem.20210314  0.572
2021 Kong W, Dimitri A, Wang W, Jung IY, Ott CJ, Fasolino M, Wang Y, Kulikovskaya I, Gupta M, Yoder T, DeNizio JE, Everett JK, Williams EF, Xu J, Scholler J, ... ... Maus MV, et al. BET bromodomain protein inhibition reverses chimeric antigen receptor extinction and reinvigorates exhausted T cells in chronic lymphocytic leukemia. The Journal of Clinical Investigation. 131. PMID 34396987 DOI: 10.1172/JCI145459  0.687
2021 Miller PG, Sperling AS, Brea EJ, Leick MB, Fell GG, Jan M, Gohil SH, Tai YT, Munshi NC, Wu CJ, Neuberg DS, Maus MV, Jacobson C, Gibson CJ, Ebert BL. Clonal hematopoiesis in patients receiving chimeric antigen receptor T-cell therapy. Blood Advances. 5: 2982-2986. PMID 34342642 DOI: 10.1182/bloodadvances.2021004554  0.478
2021 Wehrli M, Maus MV. New CARs on and off the road: challenges and new developments in CAR-T cell therapy. Current Opinion in Pharmacology. 59: 116-126. PMID 34198161 DOI: 10.1016/j.coph.2021.05.005  0.527
2021 Wehrli M, Maus MV. New CARs on and off the road: challenges and new developments in CAR-T cell therapy. Current Opinion in Pharmacology. 59: 116-126. PMID 34198161 DOI: 10.1016/j.coph.2021.05.005  0.527
2021 Weingarten-Gabbay S, Klaeger S, Sarkizova S, Pearlman LR, Chen DY, Gallagher KME, Bauer MR, Taylor HB, Dunn WA, Tarr C, Sidney J, Rachimi S, Conway HL, Katsis K, Wang Y, ... ... Maus MV, et al. Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs. Cell. PMID 34171305 DOI: 10.1016/j.cell.2021.05.046  0.332
2021 Maus MV. CD19 CAR T cells for adults with relapsed or refractory acute lymphoblastic leukaemia. Lancet (London, England). PMID 34097851 DOI: 10.1016/S0140-6736(21)01289-7  0.435
2021 Durgin JS, Henderson F, Nasrallah MP, Mohan S, Wang S, Lacey SF, Melenhorst JJ, Desai AS, Lee JYK, Maus MV, June CH, Brem S, O'Connor RS, Binder Z, O'Rourke DM. Case Report: Prolonged Survival Following EGFRvIII CAR T Cell Treatment for Recurrent Glioblastoma. Frontiers in Oncology. 11: 669071. PMID 34026647 DOI: 10.3389/fonc.2021.669071  0.626
2021 Bai Z, Lundh S, Kim D, Woodhouse S, Barrett DM, Myers RM, Grupp SA, Maus MV, June CH, Camara PG, Melenhorst JJ, Fan R. Single-cell multiomics dissection of basal and antigen-specific activation states of CD19-targeted CAR T cells. Journal For Immunotherapy of Cancer. 9. PMID 34006631 DOI: 10.1136/jitc-2020-002328  0.691
2021 Gallagher KME, Leick MB, Larson RC, Berger TR, Katsis K, Yam JY, Brini G, Grauwet K, Maus MV. SARS -CoV-2 T-cell immunity to variants of concern following vaccination. Biorxiv : the Preprint Server For Biology. PMID 33972942 DOI: 10.1101/2021.05.03.442455  0.367
2021 Johansson U, Gallagher K, Burgoyne V, Maus MV, Casey KS, Brini GG, Frigault MJ, Yam JY, Chavda N, Besley C, Lugthart S. Detection of CAR-T19 cells in peripheral blood and cerebrospinal fluid: An assay applicable to routine diagnostic laboratories. Cytometry. Part B, Clinical Cytometry. PMID 33915021 DOI: 10.1002/cyto.b.22005  0.517
2021 Yu X, Curry WT, Gerstner ER, Cahill DP, Nahed BV, Maus MV, Carter BS, Choi BD. Commentary: Chimeric Antigen Receptor T-Cell Therapy: Updates in Glioblastoma Treatment. Neurosurgery. PMID 33826726 DOI: 10.1093/neuros/nyab099  0.493
2021 Berger TR, Maus MV. Mechanisms of response and resistance to CAR T cell therapies. Current Opinion in Immunology. 69: 56-64. PMID 33752101 DOI: 10.1016/j.coi.2021.02.010  0.595
2021 Clayton KL, Mylvaganam G, Villasmil-Ocando A, Stuart H, Maus MV, Rashidian M, Ploegh HL, Walker BD. HIV-infected macrophages resist efficient NK cell-mediated killing while preserving inflammatory cytokine responses. Cell Host & Microbe. PMID 33571449 DOI: 10.1016/j.chom.2021.01.006  0.309
2021 Larson RC, Maus MV. Recent advances and discoveries in the mechanisms and functions of CAR T cells. Nature Reviews. Cancer. PMID 33483715 DOI: 10.1038/s41568-020-00323-z  0.52
2021 Jan M, Scarfò I, Larson RC, Walker A, Schmidts A, Guirguis AA, Gasser JA, Słabicki M, Bouffard AA, Castano AP, Kann MC, Cabral ML, Tepper A, Grinshpun DE, Sperling AS, ... ... Maus MV, et al. Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide. Science Translational Medicine. 13. PMID 33408186 DOI: 10.1126/scitranslmed.abb6295  0.414
2020 Maus MV, Alexander S, Bishop MR, Brudno JN, Callahan C, Davila ML, Diamonte C, Dietrich J, Fitzgerald JC, Frigault MJ, Fry TJ, Holter-Chakrabarty JL, Komanduri KV, Lee DW, Locke FL, et al. Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immune effector cell-related adverse events. Journal For Immunotherapy of Cancer. 8. PMID 33335028 DOI: 10.1136/jitc-2020-001511  0.386
2020 Benjamin R, Graham C, Yallop D, Jozwik A, Mirci-Danicar OC, Lucchini G, Pinner D, Jain N, Kantarjian H, Boissel N, Maus MV, Frigault MJ, Baruchel A, Mohty M, Gianella-Borradori A, et al. Genome-edited, donor-derived allogeneic anti-CD19 chimeric antigen receptor T cells in paediatric and adult B-cell acute lymphoblastic leukaemia: results of two phase 1 studies. Lancet (London, England). 396: 1885-1894. PMID 33308471 DOI: 10.1016/S0140-6736(20)32334-5  0.458
2020 Jacobson CA, Maus MV. C(h)AR-ting a new course in incurable lymphomas: CAR T cells for mantle cell and follicular lymphomas. Blood Advances. 4: 5858-5862. PMID 33232481 DOI: 10.1182/bloodadvances.2020003391  0.52
2020 Leick MB, Maus MV, Frigault MJ. Clinical Perspective: Treatment of Aggressive B Cell Lymphomas with FDA-Approved CAR-T Cell Therapies. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 33130313 DOI: 10.1016/j.ymthe.2020.10.022  0.472
2020 Schmidts A, Marsh LC, Srivastava AA, Bouffard AA, Boroughs AC, Scarfò I, Larson RC, Bedoya F, Choi BD, Frigault MJ, Bailey SR, Leick MB, Vatsa S, Kann MC, Prew MS, ... ... Maus MV, et al. Cell-based artificial APC resistant to lentiviral transduction for efficient generation of CAR-T cells from various cell sources. Journal For Immunotherapy of Cancer. 8. PMID 32900862 DOI: 10.1136/Jitc-2020-000990  0.638
2020 Schmidts A, Wehrli M, Maus MV. Toward Better Understanding and Management of CAR-T Cell-Associated Toxicity. Annual Review of Medicine. PMID 32776808 DOI: 10.1146/Annurev-Med-061119-015600  0.613
2020 Boroughs AC, Larson RC, Marjanovic ND, Gosik K, Castano AP, Porter CBM, Lorrey SJ, Ashenberg O, Jerby L, Hofree M, Smith-Rosario G, Morris R, Gould J, Riley LS, Berger TR, ... ... Maus MV, et al. A Distinct Transcriptional Program in Human CAR T Cells Bearing the 4-1BB Signaling Domain Revealed by scRNA-Seq. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 32755564 DOI: 10.1016/J.Ymthe.2020.07.023  0.594
2020 Jacobson CA, Hunter BD, Redd R, Rodig SJ, Chen PH, Wright K, Lipschitz M, Ritz J, Kamihara Y, Armand P, Nikiforow S, Rogalski M, Maakaron J, Jaglowski S, Maus MV, et al. Axicabtagene Ciloleucel in the Non-Trial Setting: Outcomes and Correlates of Response, Resistance, and Toxicity. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO1902103. PMID 32667831 DOI: 10.1200/Jco.19.02103  0.306
2020 Dunn GP, Cloughesy TF, Maus MV, Prins RM, Reardon DA, Sonabend AM. Emerging Immunotherapies for Malignant Glioma: From Immunogenomics to Cell Therapy. Neuro-Oncology. PMID 32615600 DOI: 10.1093/neuonc/noaa154  0.335
2020 Gutierrez C, Brown ART, Herr MM, Kadri SS, Hill B, Rajendram P, Duggal A, Turtle CJ, Patel K, Lin Y, May HP, Gallo de Moraes A, Maus MV, Frigault MJ, Brudno JN, et al. The chimeric antigen receptor-intensive care unit (CAR-ICU) initiative: Surveying intensive care unit practices in the management of CAR T-cell associated toxicities. Journal of Critical Care. 58: 58-64. PMID 32361219 DOI: 10.1016/J.Jcrc.2020.04.008  0.4
2020 Maryamchik E, Gallagher KME, Preffer FI, Kadauke S, Maus MV. New directions in chimeric antigen receptor T cell [CAR-T] therapy and related flow cytometry. Cytometry. Part B, Clinical Cytometry. PMID 32352629 DOI: 10.1002/Cyto.B.21880  0.598
2020 Weber EW, Maus MV, Mackall CL. The Emerging Landscape of Immune Cell Therapies. Cell. 181: 46-62. PMID 32243795 DOI: 10.1016/J.Cell.2020.03.001  0.428
2020 Frigault MJ, Maus MV. State of the art in CAR T cell therapy for CD19+ B cell malignancies. The Journal of Clinical Investigation. 130: 1586-1594. PMID 32235098 DOI: 10.1172/Jci129208  0.643
2020 Scarfò I, Maus MV. Unraveling the Signaling Balance of Activation and Exhaustion of CAR T Cells. Cancer Cell. 37: 143-144. PMID 32049043 DOI: 10.1016/J.Ccell.2020.01.006  0.513
2020 Nardi V, Ku N, Frigault MJ, Dubuc AM, Tsai HK, Amrein PC, Hobbs GS, Brunner AM, Narayan R, Burke ME, Foster J, Dal Cin P, Maus MV, Fathi AT, Hock H. Clinical response to larotrectinib in adult Philadelphia chromosome-like ALL with cryptic ETV6-NTRK3 rearrangement. Blood Advances. 4: 106-111. PMID 31905241 DOI: 10.1182/Bloodadvances.2019000769  0.404
2019 Wang X, Scarfò I, Schmidts A, Toner M, Maus MV, Irimia D. Dynamic Profiling of Antitumor Activity of CAR T Cells Using Micropatterned Tumor Arrays. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 6: 1901829. PMID 31832320 DOI: 10.1002/Advs.201901829  0.629
2019 Choi BD, Yu X, Castano AP, Darr H, Henderson DB, Bouffard AA, Larson RC, Scarfò I, Bailey SR, Gerhard GM, Frigault MJ, Leick MB, Schmidts A, Sagert JG, Curry WT, ... ... Maus MV, et al. CRISPR-Cas9 disruption of PD-1 enhances activity of universal EGFRvIII CAR T cells in a preclinical model of human glioblastoma. Journal For Immunotherapy of Cancer. 7: 304. PMID 31727131 DOI: 10.1186/S40425-019-0806-7  0.567
2019 Schmidts A, Ormhøj M, Choi BD, Taylor AO, Bouffard AA, Scarfò I, Larson RC, Frigault MJ, Gallagher K, Castano AP, Riley LS, Cabral ML, Boroughs AC, Velasco Cárdenas RM, Schamel W, ... ... Maus MV, et al. Rational design of a trimeric APRIL-based CAR-binding domain enables efficient targeting of multiple myeloma. Blood Advances. 3: 3248-3260. PMID 31698455 DOI: 10.1182/Bloodadvances.2019000703  0.485
2019 Mondal N, Silva M, Castano AP, Maus MV, Sackstein R. Glycoengineering of Chimeric Antigen Receptor (CAR) T-cells to Enforce E-selectin Binding. The Journal of Biological Chemistry. PMID 31628196 DOI: 10.1074/Jbc.Ra119.011134  0.583
2019 Mylvaganam G, Yanez AG, Maus M, Walker BD. Toward T Cell-Mediated Control or Elimination of HIV Reservoirs: Lessons From Cancer Immunology. Frontiers in Immunology. 10: 2109. PMID 31552045 DOI: 10.3389/Fimmu.2019.02109  0.555
2019 Ormhøj M, Scarfò I, Cabral ML, Bailey SR, Lorrey SJ, Bouffard AA, Castano AP, Larson RC, Riley LS, Schmidts A, Choi BD, Andersen RS, Cédile O, Nyvold CG, Haaber J, ... ... Maus MV, et al. Chimeric antigen receptor T cells targeting CD79b show efficacy in lymphoma with or without co-targeting CD19. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31439577 DOI: 10.1158/1078-0432.Ccr-19-1337  0.631
2019 Choi BD, Yu X, Castano AP, Bouffard AA, Schmidts A, Larson RC, Bailey SR, Boroughs AC, Frigault MJ, Leick MB, Scarfò I, Cetrulo CL, Demehri S, Nahed BV, Cahill DP, ... ... Maus MV, et al. CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity. Nature Biotechnology. PMID 31332324 DOI: 10.1038/S41587-019-0192-1  0.631
2019 Frigault MJ, Dietrich J, Martinez-Lage M, Leick M, Choi BD, DeFilipp Z, Chen YB, Abramson J, Crombie J, Armand P, Nayak L, Panzini C, Riley LS, Gallagher K, Maus M. Tisagenlecleucel CAR-T Cell Therapy in Secondary CNS Lymphoma. Blood. PMID 31320380 DOI: 10.1182/Blood.2019001694  0.639
2019 Li M, Chin LY, Shukor S, Tamayo AG, Maus MV, Parekkadan B. Effects of intermittent T-cell cluster disaggregation on proliferative capacity and checkpoint marker expression. Autoimmunity. 1-6. PMID 31238751 DOI: 10.1080/08916934.2019.1630064  0.566
2019 Bailey SR, Maus MV. Gene editing for immune cell therapies. Nature Biotechnology. PMID 31160723 DOI: 10.1038/S41587-019-0137-8  0.583
2019 Baeuerle PA, Ding J, Patel E, Thorausch N, Horton H, Gierut J, Scarfo I, Choudhary R, Kiner O, Krishnamurthy J, Le B, Morath A, Baldeviano GC, Quinn J, Tavares P, ... ... Maus MV, et al. Synthetic TRuC receptors engaging the complete T cell receptor for potent anti-tumor response. Nature Communications. 10: 2087. PMID 31064990 DOI: 10.1038/S41467-019-10097-0  0.651
2019 Scarfò I, Frigault MJ, Maus MV. CAR-Based Approaches to Cutaneous T-Cell Lymphoma. Frontiers in Oncology. 9: 259. PMID 31058076 DOI: 10.3389/Fonc.2019.00259  0.644
2019 Raje N, Berdeja J, Lin Y, Siegel D, Jagannath S, Madduri D, Liedtke M, Rosenblatt J, Maus MV, Turka A, Lam LP, Morgan RA, Friedman K, Massaro M, Wang J, et al. Anti-BCMA CAR T-Cell Therapy bb2121 in Relapsed or Refractory Multiple Myeloma. The New England Journal of Medicine. 380: 1726-1737. PMID 31042825 DOI: 10.1056/Nejmoa1817226  0.625
2019 Leick M, Maus MV. Wishing on a CAR: Understanding the Scope of Intrinsic T-cell Deficits in Patients with Cancer. Cancer Discovery. 9: 466-468. PMID 30936218 DOI: 10.1158/2159-8290.Cd-19-0073  0.564
2019 Boroughs AC, Larson RC, Choi BD, Bouffard AA, Riley LS, Schiferle E, Kulkarni AS, Cetrulo CL, Ting D, Blazar BR, Demehri S, Maus MV. Chimeric antigen receptor costimulation domains modulate human regulatory T cell function. Jci Insight. 5. PMID 30869654 DOI: 10.1172/Jci.Insight.126194  0.565
2019 Garfall AL, Stadtmauer EA, Hwang WT, Lacey SF, Melenhorst JJ, Krevvata M, Carroll MP, Matsui WH, Wang Q, Dhodapkar MV, Dhodapkar K, Das R, Vogl DT, Weiss BM, Cohen AD, ... ... Maus MV, et al. Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma. Jci Insight. 4. PMID 30830874 DOI: 10.1172/jci.insight.127684  0.565
2019 Karschnia P, Jordan JT, Forst DA, Arrillaga-Romany IC, Batchelor TT, Baehring JM, Clement NF, Gonzalez Castro LN, Herlopian A, Maus MV, Schwaiblmair MH, Soumerai JD, Takvorian RW, Hochberg EP, Barnes JA, et al. Clinical presentation, management, and biomarkers of neurotoxicity after adoptive immunotherapy with CAR T-cells. Blood. PMID 30808634 DOI: 10.1182/Blood-2018-12-893396  0.573
2019 Kleinstiver BP, Sousa AA, Walton RT, Tak YE, Hsu JY, Clement K, Welch MM, Horng JE, Malagon-Lopez J, Scarfò I, Maus MV, Pinello L, Aryee MJ, Joung JK. Engineered CRISPR-Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing. Nature Biotechnology. PMID 30742127 DOI: 10.1038/S41587-018-0011-0  0.376
2019 Guedan S, Calderon H, Posey AD, Maus MV. Engineering and Design of Chimeric Antigen Receptors. Molecular Therapy. Methods & Clinical Development. 12: 145-156. PMID 30666307 DOI: 10.1016/J.Omtm.2018.12.009  0.532
2019 Leick MB, Maus MV. CAR-T cells beyond CD19, UnCAR-Ted territory. American Journal of Hematology. PMID 30632631 DOI: 10.1002/Ajh.25398  0.592
2019 Fathi A, Ebert B, Motamedi M, Parikh AR, Drapkin B, Lin JJ, Saladi SV, Maus M. 10th Chabner Colloquium: Answering the Big Questions in Cancer ResearchAbstract 1 – IDH Inhibition in Acute Myeloid Leukemia: Emergence of a New Therapeutic EraAbstract 2 – Clonal HematopoiesisAbstract 3 – Epigenetic Reversal of Chemotherapy Resistance in CancersAbstract 4 – ctDNA, a Biomarker of Residual Disease and Tumor Response in Gastrointestinal CancersAbstract 5 – Cross‐Resistance in Small Cell Lung CancerAbstract 6 – RET as a Target in Lung CancerAbstract 7 – Targeting SWI/SNF‐Hippo Axis in Squamous CancersAbstract 8 – Innovations in Cell Therapy The Oncologist. 24: S1-S4. DOI: 10.1634/Theoncologist.2019-Ma-1  0.349
2019 Scarfò I, Gallagher K, Maus MV, Larson R, Sheehan M, Brini G, Bornheimer S, Hanley MB, Frigault M, Leick M, Chekmasova A. Application of a Standardized Flow Cytometry Panel for Defining and Monitoring the Immunophenotype of CAR-T Cells Blood. 134: 5626-5626. DOI: 10.1182/Blood-2019-128745  0.603
2019 Leick M, Scarfò I, Choi BD, Larson R, Bouffard AA, Castano A, Cabral ML, Schmidts A, Frigault MJ, Maus MV. Use of CD70 Targeted Chimeric Antigen Receptor (CAR) T Cells for the Treatment of Acute Myeloid Leukemia (AML) Blood. 134: 4443-4443. DOI: 10.1182/Blood-2019-127154  0.607
2019 Jan M, Castano A, Walker A, Guirguis AA, Gasser JA, Bouffard AA, Slabicki M, Tepper A, Grinshpun DE, Kyung T, Sievers Q, Birnbaum ME, Maus MV, Ebert BL. Exploiting the Zinc Finger Degrome Targeted By Lenalidomide to Engineer Reversible Off-Switch Degradable Chimeric Antigen Receptors Blood. 134: 866-866. DOI: 10.1182/Blood-2019-124210  0.567
2019 Choi BD, Yu X, Castano AP, Bouffard AA, Curry WT, Carter BS, Maus MV. Abstract LB-066: BiTE-armored CARs overcome antigen escape in EGFRvIII-targeted therapy for glioblastoma Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Lb-066  0.642
2019 Horton H, Ding J, Shah S, Gierut J, Thorausch N, Morath A, Shamel W, Maus M, Baeuerle P, Hofmeister R, Getts DR. Abstract 2330: Preclinical evaluation of TC-110: CD19-specific T cell receptor (TCR) fusion construct (TRuC™) T cell for the treatment of hematologic malignancies Cancer Research. 79: 2330-2330. DOI: 10.1158/1538-7445.Am2019-2330  0.679
2019 Choi BD, Yu X, Castano AP, Bouffard AA, Schmidts A, Larson RC, Bailey SR, Boroughs AC, Frigault MJ, Leick MB, Scarfo I, Cetrulo CL, Demehri S, Nahed BV, Cahill DP, ... ... Maus MV, et al. Bispecific T-Cell Engager -Armored Chimeric Antigen Receptor T Cells Overcome Antigen Escape From EGFRvIII-Targeted Therapy For Glioblastoma Neurosurgery. 66. DOI: 10.1093/Neuros/Nyz310_154  0.648
2018 Aijaz A, Li M, Smith D, Khong D, LeBlon C, Fenton OS, Olabisi RM, Libutti S, Tischfield J, Maus MV, Deans R, Barcia RN, Anderson DG, Ritz J, Preti R, et al. Biomanufacturing for clinically advanced cell therapies. Nature Biomedical Engineering. 2: 362-376. PMID 31011198 DOI: 10.1038/S41551-018-0246-6  0.515
2018 Lee DW, Santomasso BD, Locke FL, Ghobadi A, Turtle CJ, Brudno JN, Maus MV, Park JH, Mead E, Pavletic S, Go WY, Eldjerou L, Gardner RA, Frey N, Curran KJ, et al. ASBMT Consensus Grading for Cytokine Release Syndrome and Neurological Toxicity Associated with Immune Effector Cells. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 30592986 DOI: 10.1016/J.Bbmt.2018.12.758  0.538
2018 Fishman JA, Hogan JI, Maus MV. Inflammatory and Infectious Syndromes Associated with Cancer Immunotherapies. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 30520987 DOI: 10.1093/Cid/Ciy1025  0.485
2018 Boyiadzis MM, Dhodapkar MV, Brentjens RJ, Kochenderfer JN, Neelapu SS, Maus MV, Porter DL, Maloney DG, Grupp SA, Mackall CL, June CH, Bishop MR. Chimeric antigen receptor (CAR) T therapies for the treatment of hematologic malignancies: clinical perspective and significance. Journal For Immunotherapy of Cancer. 6: 137. PMID 30514386 DOI: 10.1186/S40425-018-0460-5  0.668
2018 Li M, Chin LY, Shukor S, Tamayo A, Maus MV, Parekkadan B. Closed loop bioreactor system for the ex vivo expansion of human T cells. Cytotherapy. PMID 30497956 DOI: 10.1016/J.Jcyt.2018.10.009  0.453
2018 Schmidts A, Maus MV. Making CAR T Cells a Solid Option for Solid Tumors. Frontiers in Immunology. 9: 2593. PMID 30467505 DOI: 10.3389/Fimmu.2018.02593  0.642
2018 Choi BD, Maus MV, June CH, Sampson JH. ----Immunotherapy for Glioblastoma: Adoptive T-cell Strategies. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30446589 DOI: 10.1158/1078-0432.Ccr-18-1625  0.716
2018 Scarfò I, Ormhøj M, Frigault MJ, Castano AP, Lorrey S, Bouffard AA, van Scoyk A, Rodig SJ, Shay AJ, Aster JC, Preffer FI, Weinstock DM, Maus MV. Anti-CD37 chimeric antigen receptor T cells are active against B and T cell lymphomas. Blood. PMID 30089630 DOI: 10.1182/Blood-2018-04-842708  0.642
2018 Tang L, Zheng Y, Melo MB, Mabardi L, Castaño AP, Xie YQ, Li N, Kudchodkar SB, Wong HC, Jeng EK, Maus MV, Irvine DJ. Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery. Nature Biotechnology. PMID 29985479 DOI: 10.1038/Nbt.4181  0.64
2018 Leick MB, Maus MV. Toxicities associated with immunotherapies for hematologic malignancies. Best Practice & Research. Clinical Haematology. 31: 158-165. PMID 29909916 DOI: 10.1016/J.Beha.2018.03.004  0.621
2018 Maus MV. Tumour tamed by transfer of one T cell. Nature. 558: 193-195. PMID 29895908 DOI: 10.1038/D41586-018-05251-5  0.529
2018 Choi BD, Curry WT, Carter BS, Maus MV. Chimeric antigen receptor T-cell immunotherapy for glioblastoma: practical insights for neurosurgeons. Neurosurgical Focus. 44: E13. PMID 29852773 DOI: 10.3171/2018.2.Focus17788  0.591
2018 Kloss CC, Lee J, Zhang A, Chen F, Melenhorst JJ, Lacey SF, Maus MV, Fraietta JA, Zhao Y, June CH. Dominant-Negative TGF-β Receptor Enhances PSMA-Targeted Human CAR T Cell Proliferation And Augments Prostate Cancer Eradication. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29807781 DOI: 10.1016/J.Ymthe.2018.05.003  0.566
2018 Garfall AL, Stadtmauer EA, Hwang WT, Lacey SF, Melenhorst JJ, Krevvata M, Carroll MP, Matsui WH, Wang Q, Dhodapkar MV, Dhodapkar K, Das R, Vogl DT, Weiss BM, Cohen AD, ... ... Maus MV, et al. Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma. Jci Insight. 3. PMID 29669947 DOI: 10.1172/Jci.Insight.120505  0.681
2018 Berdeja JG, Lin Y, Kochenderfer J, Raje NS, Munshi NC, Siegel DSD, Liedtke M, Madduri D, Rosenblatt J, Maus MV, Turka A, Lam LP, Hege K, Campbell TB, Massaro M, et al. Association of high baseline ferritin with tocilizumab administration for CRS in relapsed/refractory multiple myeloma patients treated with bb2121 anti-BCMA CAR T cells. Journal of Clinical Oncology. 36: e15062-e15062. DOI: 10.1200/Jco.2018.36.15_Suppl.E15062  0.523
2018 Munshi NC, Berdeja JG, Lin Y, Kochenderfer J, Raje NS, Liedtke M, Jagannath S, Madduri D, Rosenblatt J, Maus MV, Turka A, Lam LP, Hege K, Campbell TB, Massaro M, et al. Early MRD negativity to predict deepening myeloma response in relapsed/refractory multiple myeloma (RRMM) patients treated with bb2121 anti-BCMA CAR T cells. Journal of Clinical Oncology. 36: 8024-8024. DOI: 10.1200/Jco.2018.36.15_Suppl.8024  0.528
2018 Raje NS, Berdeja JG, Lin Y, Munshi NC, Siegel DSD, Liedtke M, Jagannath S, Madduri D, Rosenblatt J, Maus MV, Turka A, Lam LP, Morgan RA, Quigley T, Massaro M, et al. bb2121 anti-BCMA CAR T-cell therapy in patients with relapsed/refractory multiple myeloma: Updated results from a multicenter phase I study. Journal of Clinical Oncology. 36: 8007-8007. DOI: 10.1200/Jco.2018.36.15_Suppl.8007  0.647
2018 Schmidts A, Ormhoj M, Taylor AO, Lorrey SJ, Scarfò I, Frigault MJ, Choi BD, Maus MV. Engineering an Optimized Trimeric APRIL-Based CAR to Broaden Targetability of Multiple Myeloma Blood. 132: 2059-2059. DOI: 10.1182/Blood-2018-99-119633  0.612
2018 Mondal N, Silva M, Castano A, Maus MV, Sackstein R. Overcoming a Critical Obstacle Towards Effective and Safe CAR T-Cell Therapeutics Blood. 132: 2056-2056. DOI: 10.1182/Blood-2018-99-118675  0.636
2018 Jacobson CA, Hunter B, Armand P, Kamihara Y, Ritz J, Rodig SJ, Wright K, Lipschitz M, Redd RA, Maus MV, Chen Y, Abramson JS, Kline J, Cohen JB, Maakaron J, et al. Axicabtagene Ciloleucel in the Real World: Outcomes and Predictors of Response, Resistance and Toxicity Blood. 132: 92-92. DOI: 10.1182/Blood-2018-99-117199  0.405
2018 Maus M. Abstract IA19: New directions in T cell therapies for cancer Cancer Immunology Research. 6. DOI: 10.1158/2326-6074.Tumimm17-Ia19  0.611
2018 Patel E, Ding J, Thorausch N, Krishnamurthy J, Choudhary R, Weiler S, Le B, Tavares P, Zieba A, Quinn J, Wang Y, Schamel W, Scarfo I, Maus M, Baeuerle P, et al. Abstract 3584: Characterization of a novel class of engineered (TCR) fusion constructs (TRuCTMs) aimed to treat solid tumors Cancer Research. 78: 3584-3584. DOI: 10.1158/1538-7445.Am2018-3584  0.64
2017 Choi BD, O'Rourke DM, Maus MV. Engineering Chimeric Antigen Receptor T cells to Treat Glioblastoma. The Journal of Targeted Therapies in Cancer. 6: 22-25. PMID 29167820  0.576
2017 O'Rourke DM, Nasrallah MP, Desai A, Melenhorst JJ, Mansfield K, Morrissette JJD, Martinez-Lage M, Brem S, Maloney E, Shen A, Isaacs R, Mohan S, Plesa G, Lacey SF, Navenot JM, ... ... Maus MV, et al. A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma. Science Translational Medicine. 9. PMID 28724573 DOI: 10.1126/Scitranslmed.Aaa0984  0.677
2017 Long M, Beckwith K, Do P, Mundy BL, Gordon A, Lehman AM, Maddocks KJ, Cheney C, Jones JA, Flynn JM, Andritsos LA, Awan F, Fraietta JA, June CH, Maus MV, et al. Ibrutinib treatment improves T cell number and function in CLL patients. The Journal of Clinical Investigation. PMID 28714866 DOI: 10.1172/Jci89756  0.578
2017 Sampson JH, Maus MV, June CH. Immunotherapy for Brain Tumors. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2017728089. PMID 28640704 DOI: 10.1200/Jco.2017.72.8089  0.457
2017 Maus MV, Nikiforow S. The Why, what, and How of the New FACT standards for immune effector cells. Journal For Immunotherapy of Cancer. 5: 36. PMID 28428885 DOI: 10.1186/S40425-017-0239-0  0.528
2017 Scarfò I, Maus MV. Current approaches to increase CAR T cell potency in solid tumors: targeting the tumor microenvironment. Journal For Immunotherapy of Cancer. 5: 28. PMID 28331617 DOI: 10.1186/S40425-017-0230-9  0.57
2017 Tanyi JL, Stashwick C, Plesa G, Morgan MA, Porter D, Maus MV, June CH. Possible Compartmental Cytokine Release Syndrome in a Patient With Recurrent Ovarian Cancer After Treatment With Mesothelin-targeted CAR-T Cells. Journal of Immunotherapy (Hagerstown, Md. : 1997). PMID 28234665 DOI: 10.1097/Cji.0000000000000160  0.697
2017 Ormhøj M, Bedoya F, Frigault MJ, Maus MV. CARs in the Lead Against Multiple Myeloma. Current Hematologic Malignancy Reports. PMID 28233151 DOI: 10.1007/S11899-017-0373-2  0.65
2017 Maus MV. Immunology: T-cell tweaks to target tumours. Nature. PMID 28225762 DOI: 10.1038/Nature21506  0.645
2017 Bedoya F, Frigault MJ, Maus MV. The Flipside of the Power of Engineered T Cells: Observed and Potential Toxicities of Genetically Modified T Cells as Therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 25: 314-320. PMID 28153085 DOI: 10.1016/J.Ymthe.2016.11.011  0.586
2017 Berdeja JG, Lin Y, Raje NS, Siegel DSD, Munshi NC, Liedtke M, Jagannath S, Maus MV, Turka A, Lam LP, Hege K, Morgan R, Quigley MT, Kochenderfer J. First-in-human multicenter study of bb2121 anti-BCMA CAR T-cell therapy for relapsed/refractory multiple myeloma: Updated results. Journal of Clinical Oncology. 35: 3010-3010. DOI: 10.1200/Jco.2017.35.15_Suppl.3010  0.579
2017 Berdeja JG, Lin Y, Raje N, Munshi N, Siegel D, Liedtke M, Jagannath S, Maus MV, Turka A, Lam LP, Hege K, Morgan RA, Quigley MT, Kochenderfer JN. Durable Clinical Responses in Heavily Pretreated Patients with Relapsed/Refractory Multiple Myeloma: Updated Results from a Multicenter Study of bb2121 Anti-Bcma CAR T Cell Therapy Blood. 130: 740-740. DOI: 10.1182/Blood.V130.Suppl_1.740.740  0.581
2017 Castano A, Tang L, Kudchodkar S, Darrell I, Maus M. Abstract B59: Enhancing T-cell therapy through TCR signaling-responsive nanogel drug delivery Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-B59  0.663
2017 Maus MV. Immunoengineering: Valet parking for CAR genes Nature Biomedical Engineering. 1. DOI: 10.1038/S41551-017-0085  0.447
2016 Maus MV, Plotkin J, Jakka G, Stewart-Jones G, Rivière I, Merghoub T, Wolchok J, Renner C, Sadelain M. An MHC-restricted antibody-based chimeric antigen receptor requires TCR-like affinity to maintain antigen specificity. Molecular Therapy Oncolytics. 3: 1-9. PMID 29675462 DOI: 10.1038/Mto.2016.23  0.541
2016 Ruella M, Maus MV. Catch me if you can: Leukemia Escape after CD19-Directed T Cell Immunotherapies. Computational and Structural Biotechnology Journal. 14: 357-362. PMID 27761200 DOI: 10.1016/J.Csbj.2016.09.003  0.602
2016 Maus MV, June CH. Making Better Chimeric Antigen Receptors for Adoptive T-cell Therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 22: 1875-84. PMID 27084741 DOI: 10.1158/1078-0432.Ccr-15-1433  0.757
2016 Fesnak A, Lin C, Siegel DL, Maus MV. CAR-T Cell Therapies From the Transfusion Medicine Perspective. Transfusion Medicine Reviews. PMID 27067907 DOI: 10.1016/J.Tmrv.2016.03.001  0.642
2016 Fraietta JA, Schwab RD, Maus MV. Improving therapy of chronic lymphocytic leukemia with chimeric antigen receptor T cells. Seminars in Oncology. 43: 291-9. PMID 27040708 DOI: 10.1053/J.Seminoncol.2016.02.006  0.671
2016 Frigault MJ, Maus MV. Chimeric antigen receptor-modified T cells strike back. International Immunology. PMID 27021308 DOI: 10.1093/Intimm/Dxw018  0.664
2016 Maus MV, Levine BL. Chimeric Antigen Receptor T-Cell Therapy for the Community Oncologist. The Oncologist. PMID 27009942 DOI: 10.1634/Theoncologist.2015-0421  0.648
2016 Zhukovsky EA, Morse RJ, Maus MV. Bispecific antibodies and CARs: generalized immunotherapeutics harnessing T cell redirection. Current Opinion in Immunology. 40: 24-35. PMID 26963133 DOI: 10.1016/J.Coi.2016.02.006  0.623
2016 Maus MV. Innate immune signaling in CLL. Blood. 127: 376-8. PMID 26823508 DOI: 10.1182/Blood-2015-11-679845  0.305
2016 Ruella M, Kenderian SS, Shestova O, Fraietta JA, Qayyum S, Zhang Q, Maus MV, Liu X, Nunez-Cruz S, Klichinsky M, Kawalekar OU, Lacey SF, Milone M, Mato AR, Schuster SJ, et al. The Addition of the BTK inhibitor Ibrutinib to Anti-CD19 Chimeric Antigen Receptor T Cells (CART19) Improves Responses against Mantle Cell Lymphoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26819453 DOI: 10.1158/1078-0432.Ccr-15-1527  0.682
2016 Fraietta JA, Beckwith KA, Patel PR, Ruella M, Zheng Z, Barrett DM, Lacey SF, Melenhorst JJ, McGettigan SE, Cook DR, Zhang C, Xu J, Do P, Hulitt J, Kudchodkar SB, ... ... Maus MV, et al. Ibrutinib enhances chimeric antigen receptor T-cell engraftment and efficacy in leukemia. Blood. PMID 26813675 DOI: 10.1182/Blood-2015-11-679134  0.748
2016 O'Rourke DM, Nasrallah M, Morrissette JJ, Melenhorst JJ, Lacey SF, Mansfield K, Martinez-Lage M, Desai AS, Brem S, Maloney E, Mohan S, Wang S, Verma G, Navenot J, Shen A, ... ... Maus MV, et al. Pilot study of T cells redirected to EGFRvIII with a chimeric antigen receptor in patients with EGFRvIII+ glioblastoma. Journal of Clinical Oncology. 34: 2067-2067. DOI: 10.1200/Jco.2016.34.15_Suppl.2067  0.643
2016 Garfall AL, Stadtmauer EA, Maus MV, Hwang W, Vogl DT, Cohen AD, Weiss BM, Porter DL, Frey N, Milone M, Mangan P, Krevvata M, Ayers E, Dengel K, Kerr ND, et al. Pilot Study of Anti-CD19 Chimeric Antigen Receptor T Cells (CTL019) in Conjunction with Salvage Autologous Stem Cell Transplantation for Advanced Multiple Myeloma Blood. 128: 974-974. DOI: 10.1182/Blood.V128.22.974.974  0.595
2016 Jesuraj NJ, Cole JM, Bedoya F, Wells SB, Qin G, Kevlahan S, Maus MV, Ball AJ. A Novel Phase-Change Hydrogel Substrate for T Cell Activation Promotes Increased Expansion of CD8+ Cells Expressing Central Memory and Naive Phenotype Markers Blood. 128: 3368-3368. DOI: 10.1182/Blood.V128.22.3368.3368  0.527
2016 Long M, Beckwith KA, Do P, Bethany ML, Gordon G, Lehman AM, Maddocks KJ, Cheney C, Jones J, Andritsos LA, Awan FT, Fraietta JA, June CH, Maus MV, Woyach JA, et al. Ibrutinib Represents a Novel Class of Immune Modulating Therapeutics That Enhances the Survival of Activated T Cells in Vitro and In Vivo through a Non-BTK Mediated Mechanism Blood. 128: 3238-3238. DOI: 10.1182/Blood.V128.22.3238.3238  0.714
2016 Cogdill AP, Boesteanu A, Xu C, Haines K, Scholler J, Fraietta J, Zhao Y, Liu X, Morrissette J, Levine B, Lacey S, Loew A, Singh R, Brogdon J, O'Rourke DM, ... Maus MV, et al. Abstract B139: Toxicity testing of EGFRvIII CAR-based immunotherapy of glioblastoma: From bench to bedside Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-B139  0.714
2016 O’Rourke DM, Nasrallah MP, Morrissette J, Melenhorst JJ, Lacey SF, Mansfield K, Martinez-Lage M, Desai A, Brem S, Maloney E, Mohan S, Wang S, Verma G, Navenot J, Shen A, ... ... Maus MV, et al. Abstract LB-083: Phase I study of T cells redirected to EGFRvIII with a chimeric antigen receptor in patients with EGFRvIII+ glioblastoma Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-083  0.703
2015 Miller BC, Maus MV. CD19-Targeted CAR T Cells: A New Tool in the Fight against B Cell Malignancies. Oncology Research and Treatment. 38: 683-90. PMID 26633875 DOI: 10.1159/000442170  0.658
2015 Maus MV, Powell DJ. Chimeric Antigen Receptor T-Cells: New Approaches to Improve Their Efficacy and Reduce Toxicity. Cancer Journal (Sudbury, Mass.). 21: 475-9. PMID 26588679 DOI: 10.1097/Ppo.0000000000000155  0.622
2015 Maus MV. Designing CAR T cells for glioblastoma. Oncoimmunology. 4: e1048956. PMID 26587317 DOI: 10.1080/2162402X.2015.1048956  0.595
2015 Gill S, Maus MV, Porter DL. Chimeric antigen receptor T cell therapy: 25years in the making. Blood Reviews. PMID 26574053 DOI: 10.1016/J.Blre.2015.10.003  0.612
2015 Garfall AL, Maus MV, Hwang WT, Lacey SF, Mahnke YD, Melenhorst JJ, Zheng Z, Vogl DT, Cohen AD, Weiss BM, Dengel K, Kerr ND, Bagg A, Levine BL, June CH, et al. Chimeric Antigen Receptor T Cells against CD19 for Multiple Myeloma. The New England Journal of Medicine. 373: 1040-7. PMID 26352815 DOI: 10.1056/Nejmoa1504542  0.655
2015 Johnson LA, Scholler J, Ohkuri T, Kosaka A, Patel PR, McGettigan SE, Nace AK, Dentchev T, Thekkat P, Loew A, Boesteanu AC, Cogdill AP, Chen T, Fraietta JA, Kloss CC, ... ... Maus MV, et al. Rational development and characterization of humanized anti-EGFR variant III chimeric antigen receptor T cells for glioblastoma. Science Translational Medicine. 7: 275ra22. PMID 25696001 DOI: 10.1126/Scitranslmed.Aaa4963  0.698
2015 Garfall AL, Maus MV, Lacey SF, Mahnke YD, Melenhorst JJ, Zheng Z, Vogl DT, Cohen AD, Weiss BM, Dengel K, Kerr ND, Hwang W, Levine B, June CH, Stadtmauer EA. Safety and efficacy of anti-CD19 chimeric antigen receptor (CAR)-modified autologous T cells (CTL019) in advanced multiple myeloma. Journal of Clinical Oncology. 33: 8517-8517. DOI: 10.1200/Jco.2015.33.15_Suppl.8517  0.616
2015 Ruella M, Kenderian SS, Shestova O, Fraietta JA, Qayyum S, Zhang Q, Maus MV, Liu X, Nunez-Cruz S, Klichinsky M, Kawalekar OU, Milone MC, Lacey SF, Mato A, Schuster SJ, et al. The Addition of the BTK Inhibitor Ibrutinib to Anti-CD19 Chimeric Antigen Receptor T Cells (CART19) Improves Engraftment and Antitumor Responses Against Mantle Cell Lymphoma Blood. 126: 704-704. DOI: 10.1182/Blood.V126.23.704.704  0.605
2015 Cogdill AP, Boesteanu A, Haines K, Fraietta J, Scholler J, Loew A, Thekkat P, Brogdon J, Maus MV, June C, Johnson LA. Abstract B05: A biologic screen to evaluate potential toxicity of chimeric antigen receptor modified T cells against primary normal human tissues Cancer Immunology Research. 3. DOI: 10.1158/2326-6074.Tumimm14-B05  0.697
2015 Tanyi JL, Haas AR, Beatty GL, Morgan MA, Stashwick CJ, O'Hara MH, Porter DL, Maus MV, Levine BL, Lacey SF, Nelson AM, McGarvey M, Kerr ND, Plesa G, June CH. Abstract CT105: Safety and feasibility of chimeric antigen receptor modified T cells directed against mesothelin (CART-meso) in patients with mesothelin expressing cancers Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Ct105  0.668
2015 Maus MV. The ultimate combination immunotherapy Science Translational Medicine. 7: 279ec44-279ec44. DOI: 10.1126/Scitranslmed.Aaa9868  0.349
2015 Maus MV. T cells in a (polymer) matrix Science Translational Medicine. 7: 273ec21. DOI: 10.1126/Scitranslmed.Aaa5559  0.628
2015 O'Rourke D, Desai A, Morrissette J, Martinez-Lage M, Nasrallah M, Brem S, Maloney E, Shen A, Mohan S, Wang S, Verma G, Lacey S, Melenhorst J, Navenot J, Zheng Z, ... ... Maus M, et al. IMCT-15PILOT STUDY OF T CELLS REDIRECTED TO EGFRvIII WITH A CHIMERIC ANTIGEN RECEPTOR IN PATIENTS WITH EGFRvIII+ GLIOBLASTOMA Neuro-Oncology. 17: v110.4-v111. DOI: 10.1093/Neuonc/Nov218.15  0.666
2015 Kudchodkar SB, Tang L, Jeng EK, Wong HC, Irvine DJ, Maus MV. 517. Improving CAR T Cell Efficacy for Solid Tumors By Nanogel-Based Delivery of Immunomodulatory Proteins Molecular Therapy. 23: S207. DOI: 10.1016/S1525-0016(16)34126-0  0.637
2014 Johnson LA, Scholler J, Ohkuri T, Kosaka A, Patel PR, McGettigan SE, Nace A, Thekkat P, Loew A, Chen TJ, Fraietta JA, Posey AD, Boesteanu AC, Cogdill AP, Engels B, ... ... Maus M, et al. Pre-clinical validation of a humanized anti-EGFR variant III chimeric antigen receptor and phase I trial of CART-EGFRvIII in glioblastoma Journal For Immunotherapy of Cancer. 2: 1-1. PMID 25746013 DOI: 10.1186/2051-1426-2-S3-O1  0.647
2014 June CH, Maus MV, Plesa G, Johnson LA, Zhao Y, Levine BL, Grupp SA, Porter DL. Engineered T cells for cancer therapy. Cancer Immunology, Immunotherapy : Cii. 63: 969-75. PMID 24943274 DOI: 10.1007/S00262-014-1568-1  0.596
2014 Maus MV, June CH. CARTs on the road for myeloma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 3899-901. PMID 24919574 DOI: 10.1158/1078-0432.Ccr-14-0721  0.697
2014 Beatty GL, Haas AR, Maus MV, Torigian DA, Soulen MC, Plesa G, Chew A, Zhao Y, Levine BL, Albelda SM, Kalos M, June CH. Mesothelin-specific chimeric antigen receptor mRNA-engineered T cells induce anti-tumor activity in solid malignancies. Cancer Immunology Research. 2: 112-20. PMID 24579088 DOI: 10.1158/2326-6066.Cir-13-0170  0.693
2014 Maus MV, Grupp SA, Porter DL, June CH. Antibody-modified T cells: CARs take the front seat for hematologic malignancies. Blood. 123: 2625-35. PMID 24578504 DOI: 10.1182/Blood-2013-11-492231  0.691
2014 Maus MV, Fraietta JA, Levine BL, Kalos M, Zhao Y, June CH. Adoptive immunotherapy for cancer or viruses. Annual Review of Immunology. 32: 189-225. PMID 24423116 DOI: 10.1146/Annurev-Immunol-032713-120136  0.566
2014 Garfall AL, Fraietta JA, Maus MV. Immunotherapy with chimeric antigen receptors for multiple myeloma. Discovery Medicine. 17: 37-46. PMID 24411699  0.454
2014 Maus MV. Immunology: T cells through the age(s) Science Translational Medicine. 6. DOI: 10.1126/Scitranslmed.Aaa3460  0.536
2014 Maus MV. Immunology: T cells through the age(s) Science Translational Medicine. 6. DOI: 10.1126/scitranslmed.aaa3460  0.414
2014 Maus MV. CAR T Cells Advance to the Next Level Science Translational Medicine. 6: 261ec190-261ec190. DOI: 10.1126/Scitranslmed.Aaa1533  0.63
2014 Maus MV. A cancer drug promotes hair growth Science Translational Medicine. 6. DOI: 10.1126/Scitranslmed.3010412  0.48
2014 Maus MV. Hybrid CARs for Cancer? Science Translational Medicine. 6: 249ec139-249ec139. DOI: 10.1126/Scitranslmed.3010119  0.65
2014 Maus MV. Viewing T cell biology through a genomic lens Science Translational Medicine. 6. DOI: 10.1126/Scitranslmed.3009627  0.541
2014 Maus MV. The long-awaited marriage of cancer genomics and immunotherapy bears fruit Science Translational Medicine. 6. DOI: 10.1126/Scitranslmed.3009312  0.427
2014 Maus MV. The chicken or the egg? Checkpoint markers identify tumor-specific T cells in melanoma Science Translational Medicine. 6. DOI: 10.1126/Scitranslmed.3009047  0.512
2014 Maus MV. The chicken or the egg? Checkpoint markers identify tumor-specific T cells in melanoma Science Translational Medicine. 6. DOI: 10.1126/scitranslmed.3009047  0.437
2013 Maus MV, Haas AR, Beatty GL, Albelda SM, Levine BL, Liu X, Zhao Y, Kalos M, June CH. T cells expressing chimeric antigen receptors can cause anaphylaxis in humans. Cancer Immunology Research. 1: 26-31. PMID 24777247 DOI: 10.1158/2326-6066.Cir-13-0006  0.689
2013 Maus MV, Haas AR, Beatty GL, Albelda SM, Levine BL, Liu X, Zhao Y, Kalos M, June CH. T cells expressing chimeric antigen receptors can cause anaphylaxis in humans. Cancer Immunology Research. 1: 26-31. PMID 24432303  0.646
2013 Linette GP, Stadtmauer EA, Maus MV, Rapoport AP, Levine BL, Emery L, Litzky L, Bagg A, Carreno BM, Cimino PJ, Binder-Scholl GK, Smethurst DP, Gerry AB, Pumphrey NJ, Bennett AD, et al. Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma. Blood. 122: 863-71. PMID 23770775 DOI: 10.1182/Blood-2013-03-490565  0.697
2013 Maus MV, June CH. Zoom Zoom: racing CARs for multiple myeloma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 1917-9. PMID 23444214 DOI: 10.1158/1078-0432.Ccr-13-0168  0.692
2011 Maus MV, Riviere I, Borquez-Ojeda O, Wang X, Yuan J, Merghoub T, Plotkin J, O’Reilly RJ, Wolchok JD, Sadelain M. Artificial Antigen Presenting Cells Expand NY-ESO-1 Antigen-Specific CD8+ T Cells From Patients with Melanoma Blood. 118: 4309-4309. DOI: 10.1182/Blood.V118.21.4309.4309  0.669
2009 Pien GC, Basner-Tschakarjan E, Hui DJ, Mentlik AN, Finn JD, Hasbrouck NC, Zhou S, Murphy SL, Maus MV, Mingozzi F, Orange JS, High KA. Capsid antigen presentation flags human hepatocytes for destruction after transduction by adeno-associated viral vectors. The Journal of Clinical Investigation. 119: 1688-95. PMID 19436115 DOI: 10.1172/Jci36891  0.418
2007 Zhang H, Snyder KM, Suhoski MM, Maus MV, Kapoor V, June CH, Mackall CL. 4-1BB is superior to CD28 costimulation for generating CD8+ cytotoxic lymphocytes for adoptive immunotherapy. Journal of Immunology (Baltimore, Md. : 1950). 179: 4910-8. PMID 17878391 DOI: 10.4049/Jimmunol.179.7.4910  0.791
2007 Mingozzi F, Maus MV, Hui DJ, Sabatino DE, Murphy SL, Rasko JE, Ragni MV, Manno CS, Sommer J, Jiang H, Pierce GF, Ertl HC, High KA. CD8(+) T-cell responses to adeno-associated virus capsid in humans. Nature Medicine. 13: 419-22. PMID 17369837 DOI: 10.1038/Nm1549  0.538
2007 Pien GC, Hasbrouck NC, Maus MV, Mingozzi F, High KA. Quantifying Capsid Peptide:MHC I Complexes Following Adeno-Associated Virus (AAV) Transduction Blood. 110: 3737-3737. DOI: 10.1182/Blood.V110.11.3737.3737  0.489
2006 Mingozzi F, Maus MV, Sabatino DE, Hui DJ, Rasko JE, Ragni MV, Manno CS, Ertl HC, High KA. AAV-2 Capsid-Specific CD8+ T Cells Limit the Duration of Gene Therapy in Humans and Cross-React with AAV-8 Capsid. Blood. 108: 455-455. DOI: 10.1182/Blood.V108.11.455.455  0.64
2006 Hui DJ, Mingozzi F, Maus MV, Tigges MA, Pierce GF, High KA. A Novel Splenocyte Approach for Characterizing T Cell Responses to Adeno-Associated Virus in the Normal Population: Implications on Gene Transfer. Blood. 108: 3258-3258. DOI: 10.1182/Blood.V108.11.3258.3258  0.595
2006 Maus MV, Mingozzi F, Sabatino DE, Hui D, Ragni MV, High KA. 730. T Cell Responses to AAV Vector Capsid in Normal Donors and Subjects Who Have Undergone Liver-Directed AAV-Mediated Gene Transfer Molecular Therapy. 13: S282. DOI: 10.1016/J.Ymthe.2006.08.810  0.634
2005 Mingozzi F, Maus MV, Sabatino DE, Hui D, Manno CS, Ragni MV, High KA. T Cell Responses to AAV Vector Capsid Limit the Duration of Transgene Expression in Humans after Liver-Directed Gene Therapy. Blood. 106: 3055-3055. DOI: 10.1182/Blood.V106.11.3055.3055  0.595
2004 Maus MV, Kovacs B, Kwok WW, Nepom GT, Schlienger K, Riley JL, Allman D, Finkel TH, June CH. Extensive replicative capacity of human central memory T cells. Journal of Immunology (Baltimore, Md. : 1950). 172: 6675-83. PMID 15153483 DOI: 10.4049/Jimmunol.172.11.6675  0.663
2003 Oelke M, Maus MV, Didiano D, June CH, Mackensen A, Schneck JP. Ex vivo induction and expansion of antigen-specific cytotoxic T cells by HLA-Ig-coated artificial antigen-presenting cells. Nature Medicine. 9: 619-24. PMID 12704385 DOI: 10.1038/Nm869  0.623
2003 Schlienger K, Chu CS, Woo EY, Rivers PM, Toll AJ, Hudson B, Maus MV, Riley JL, Choi Y, Coukos G, Kaiser LR, Rubin SC, Levine BL, Carroll RG, June CH. TRANCE- and CD40 ligand-matured dendritic cells reveal MHC class I-restricted T cells specific for autologous tumor in late-stage ovarian cancer patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 1517-27. PMID 12684428  0.581
2003 Maus MV, Riley JL, Kwok WW, Nepom GT, June CH. HLA tetramer-based artificial antigen-presenting cells for stimulation of CD4+ T cells. Clinical Immunology (Orlando, Fla.). 106: 16-22. PMID 12584046 DOI: 10.1016/S1521-6616(02)00017-7  0.684
2002 Thomas AK, Maus MV, Shalaby WS, June CH, Riley JL. A cell-based artificial antigen-presenting cell coated with anti-CD3 and CD28 antibodies enables rapid expansion and long-term growth of CD4 T lymphocytes. Clinical Immunology (Orlando, Fla.). 105: 259-72. PMID 12498807 DOI: 10.1006/Clim.2002.5277  0.612
2002 Kovacs B, Maus MV, Riley JL, Derimanov GS, Koretzky GA, June CH, Finkel TH. Human CD8+ T cells do not require the polarization of lipid rafts for activation and proliferation. Proceedings of the National Academy of Sciences of the United States of America. 99: 15006-11. PMID 12419850 DOI: 10.1073/Pnas.232058599  0.62
2002 Maus MV, Thomas AK, Leonard DG, Allman D, Addya K, Schlienger K, Riley JL, June CH. Ex vivo expansion of polyclonal and antigen-specific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1BB. Nature Biotechnology. 20: 143-8. PMID 11821859 DOI: 10.1038/Nbt0202-143  0.713
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