Audrey Fischer, Ph.D. - Related publications

Biology University of California, San Diego, La Jolla, CA 
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Núñez E, Muguruza-Montero A, Villarroel A. Atomistic Insights of Calmodulin Gating of Complete Ion Channels. International Journal of Molecular Sciences. 21. PMID 32075037 DOI: 10.3390/ijms21041285   
2020 Michalski K, Syrjanen JL, Henze E, Kumpf J, Furukawa H, Kawate T. The cryo-EM structure of a pannexin 1 reveals unique motifs for ion selection and inhibition. Elife. 9. PMID 32048993 DOI: 10.7554/eLife.54670   
2020 Shen L, Tian Q, Yang L, Zhang H, Shi Y, Shen Y, Zhou Z, Wu Q, Zhang Q, Zhang W. Phosphatidic acid directly binds with rice potassium channel OsAKT2 to inhibit its activity. The Plant Journal : For Cell and Molecular Biology. PMID 32128922 DOI: 10.1111/tpj.14731   
2020 Dattilo M, Penington NJ, Williams K. Regulation of TRPC5 currents by intracellular ATP: Single channel studies. Journal of Cellular Physiology. PMID 31994734 DOI: 10.1002/jcp.29602   
2020 Wang ZJ, Soohoo SM, Tiwari PB, Piszczek G, Brelidze TI. Chlorpromazine binding to the PAS domains uncovers the effect of ligand modulation on EAG channel activity. The Journal of Biological Chemistry. PMID 32047112 DOI: 10.1074/jbc.RA119.012377   
2020 Paraschiv A, Hegde S, Ganti R, Pilizota T, Šarić A. Dynamic Clustering Regulates Activity of Mechanosensitive Membrane Channels. Physical Review Letters. 124: 048102. PMID 32058787 DOI: 10.1103/PhysRevLett.124.048102   
2020 Yelshanskaya MV, Nadezhdin KD, Kurnikova MG, Sobolevsky AI. Structure and function of the calcium-selective TRP channel TRPV6. The Journal of Physiology. PMID 32073143 DOI: 10.1113/JP279024   
2020 Klipp RC, Cullinan MM, Bankston JR. Insights into the molecular mechanisms underlying the inhibition of acid-sensing ion channel 3 gating by stomatin. The Journal of General Physiology. 152. PMID 32012213 DOI: 10.1085/jgp.201912471   
2020 Gururaja Rao S, Patel NJ, Singh H. Intracellular Chloride Channels: Novel Biomarkers in Diseases. Frontiers in Physiology. 11: 96. PMID 32116799 DOI: 10.3389/fphys.2020.00096   
2020 Sanchez-Barrena MJ, Chaves-Sanjuan A, Raddatz N, Mendoza I, Cortes A, Gago F, Gonzalez-Rubio JM, Benavente JL, Quintero FJ, Pardo JM, Albert A. Recognition and activation of the plant AKT1 potassium channel by the kinase CIPK23. Plant Physiology. PMID 32015077 DOI: 10.1104/pp.19.01084   
2020 Jin P, Jan LY, Jan YN. Mechanosensitive Ion Channels: Structural Features Relevant to Mechanotransduction Mechanisms. Annual Review of Neuroscience. PMID 32084327 DOI: 10.1146/annurev-neuro-070918-050509   
2020 Taylor KC, Kang PW, Hou P, Yang ND, Kuenze G, Smith JA, Shi J, Huang H, White KM, Peng D, George AL, Meiler J, McFeeters RL, Cui J, Sanders CR. Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state. Elife. 9. PMID 32096762 DOI: 10.7554/eLife.53901   
2020 Pfeiffer P, Egorov AV, Lorenz F, Schleimer JH, Draguhn A, Schreiber S. Clusters of cooperative ion channels enable a membrane-potential-based mechanism for short-term memory. Elife. 9. PMID 32031523 DOI: 10.7554/eLife.49974   
2020 Pumroy RA, Fluck EC, Ahmed T, Moiseenkova-Bell VY. Structural insights into the gating mechanisms of TRPV channels. Cell Calcium. 87: 102168. PMID 32004816 DOI: 10.1016/j.ceca.2020.102168   
2020 Xia X, Zhang Q, Jia Y, Shu Y, Yang J, Yang H, Yan Z. Molecular basis and restoration of function deficiencies of Kv7.4 variants associated with inherited hearing loss. Hearing Research. 388: 107884. PMID 31995783 DOI: 10.1016/j.heares.2020.107884   
2020 Kelemen B, Lisztes E, Vladár A, Hanyicska M, Almássy J, Oláh A, Szöllősi AG, Pénzes Z, Posta J, Voets T, Bíró T, Tóth BI. Volatile anaesthetics inhibit the thermosensitive nociceptor ion channel transient receptor potential melastatin 3 (TRPM3). Biochemical Pharmacology. 174: 113826. PMID 31987857 DOI: 10.1016/j.bcp.2020.113826   
2020 Hou P, Kang PW, Kongmeneck AD, Yang ND, Liu Y, Shi J, Xu X, White KM, Zaydman MA, Kasimova MA, Seebohm G, Zhong L, Zou X, Tarek M, Cui J. Two-stage electro-mechanical coupling of a K channel in voltage-dependent activation. Nature Communications. 11: 676. PMID 32015334 DOI: 10.1038/s41467-020-14406-w   
2020 Bajaj S, Ong ST, Chandy KG. Contributions of natural products to ion channel pharmacology. Natural Product Reports. PMID 32065187 DOI: 10.1039/c9np00056a   
2020 Hao X, Ou M, Zhang D, Zhao W, Yang Y, Liu J, Yang H, Zhu T, Li Y, Zhou C. The Effects of General Anesthetics on Synaptic Transmission. Current Neuropharmacology. PMID 32106800 DOI: 10.2174/1570159X18666200227125854   
2020 Vikraman D, Satheesan R, Kumar KS, Mahendran KR. Nanopore Passport Control for Substrate-Specific Translocation. Acs Nano. PMID 31976649 DOI: 10.1021/acsnano.9b09408   
2020 Zhang H, Pan Y, Hu L, Hudson MA, Hofstetter KS, Xu Z, Rong M, Wang Z, Prasad BVV, Lockless SW, Chiu W, Zhou M. TrkA undergoes a tetramer-to-dimer conversion to open TrkH which enables changes in membrane potential. Nature Communications. 11: 547. PMID 31992706 DOI: 10.1038/s41467-019-14240-9   
2020 Ori H, Hazan H, Marder E, Marom S. Dynamic clamp constructed phase diagram for the Hodgkin and Huxley model of excitability. Proceedings of the National Academy of Sciences of the United States of America. PMID 32024761 DOI: 10.1073/pnas.1916514117   
2020 Lu TL, Gao ZH, Li SW, Wu SN. High Efficacy by GAL-021: A Known Intravenous Peripheral Chemoreceptor Modulator that Suppresses BK-Channel Activity and Inhibits or . Biomolecules. 10. PMID 31991782 DOI: 10.3390/biom10020188   
2020 Wang H, Cheng X, Tian J, Xiao Y, Tian T, Xu F, Hong X, Zhu MX. TRPC channels: Structure, function, regulation and recent advances in small molecular probes. Pharmacology & Therapeutics. 107497. PMID 32004513 DOI: 10.1016/j.pharmthera.2020.107497   
2020 Rook ML, Williamson A, Lueck JD, Musgaard M, Maclean DM. β11-12 linker isomerization governs Acid-sensing ion channel desensitization and recovery. Elife. 9. PMID 32031522 DOI: 10.7554/eLife.51111   
2020 Ahmed N, Pervez Mughal M, Shoaib W, Farhan Raza S, M Alahmari A. WEDM of Copper for the Fabrication of Large Surface-Area Micro-Channels A Prerequisite for the High Heat-Transfer Rate. Micromachines. 11. PMID 32046057 DOI: 10.3390/mi11020173   
2020 Huang Y, Qu J, Li X, Wei F, Zhong J, Wu Y, Cai M, Gao X, Pearson JE, Shuai J. Anti-cross-correlation between the adjacent open and closed durations of Markovian channels. Physical Review. E. 101: 012418. PMID 32069561 DOI: 10.1103/PhysRevE.101.012418   
2020 Liu G, Papa A, Katchman AN, Zakharov SI, Roybal D, Hennessey JA, Kushner J, Yang L, Chen BX, Kushnir A, Dangas K, Gygi SP, Pitt GS, Colecraft HM, Ben-Johny M, et al. Mechanism of adrenergic Ca1.2 stimulation revealed by proximity proteomics. Nature. 577: 695-700. PMID 31969708 DOI: 10.1038/s41586-020-1947-z   
2020 Jeng CJ, Fu SJ, You CY, Peng YJ, Hsiao CT, Chen TY, Tang CY. Defective Gating and Proteostasis of Human ClC-1 Chloride Channel: Molecular Pathophysiology of Myotonia Congenita. Frontiers in Neurology. 11: 76. PMID 32117034 DOI: 10.3389/fneur.2020.00076   
2020 Navarro MA, Salari A, Lin JL, Cowan LM, Penington NJ, Milescu M, Milescu LS. Sodium channels implement a molecular leaky integrator that detects action potentials and regulates neuronal firing. Elife. 9. PMID 32101161 DOI: 10.7554/eLife.54940   
2020 Loya-López S, Sandoval A, González-Ramírez R, Calderón-Rivera A, Ávalos-Fuentes A, Rodríguez-Sánchez M, Caballero R, Tovar-Soto D, Felix R, Florán B. Cdk5 phosphorylates Ca1.3 channels and regulates GABA-mediated miniature inhibitory post-synaptic currents in striato-nigral terminals. Biochemical and Biophysical Research Communications. PMID 31983427 DOI: 10.1016/j.bbrc.2020.01.084   
2020 Falcón D, Galeano-Otero I, Martín-Bórnez M, Fernández-Velasco M, Gallardo-Castillo I, Rosado JA, Ordóñez A, Smani T. TRPC Channels: Dysregulation and Ca Mishandling in Ischemic Heart Disease. Cells. 9. PMID 31936700 DOI: 10.3390/cells9010173   
2020 Milton AO, Wang T, Li W, Guo J, Zhang S. Mechanical stretch increases Kv1.5 current through an interaction between the S1-S2 linker and N-terminus of the channel. The Journal of Biological Chemistry. PMID 32122972 DOI: 10.1074/jbc.RA119.011302   
2020 Liu Y, Xu X, Zhang Y, Li M, Guo J, Yan C, Wang F, Li Y, Ding Y, Li B, Fan P. Thioridazine Induces Cardiotoxicity via Reactive Oxygen Species-Mediated hERG Channel Deficiency and L-Type Calcium Channel Activation. Oxidative Medicine and Cellular Longevity. 2020: 3690123. PMID 32064022 DOI: 10.1155/2020/3690123   
2020 Zhu A, Aierken A, Yao Z, Vu S, Tian Y, Zheng J, Yang S, Yang F. A centipede toxin causes rapid desensitization of nociceptor TRPV1 ion channel. Toxicon : Official Journal of the International Society On Toxinology. PMID 32097697 DOI: 10.1016/j.toxicon.2020.02.016   
2020 Yin J, Ge W, Han X, Guo L. Frequency-domain equalization with interference rejection combining for single carrier multiple-input multiple-output underwater acoustic communications. The Journal of the Acoustical Society of America. 147: EL138. PMID 32113331 DOI: 10.1121/10.0000711   
2020 Imenez Silva PH, Wagner CA. Potassium channels in control of renal function. Kidney International. 97: 253-255. PMID 31980072 DOI: 10.1016/j.kint.2019.10.029   
2020 Mao X, Bruneau N, Gao Q, Becq H, Jia Z, Xi H, Shu L, Wang H, Szepetowski P, Aniksztejn L. The Epilepsy of Infancy With Migrating Focal Seizures: Identification of Mutations of the Gene That Exert Inhibitory Effects on the Corresponding Heteromeric K1.1/K1.2 Potassium Channel. Frontiers in Cellular Neuroscience. 14: 1. PMID 32038177 DOI: 10.3389/fncel.2020.00001   
2020 Bhatiya S, Choudhury S, Gari M, Singh P, Shukla A, Garg SK. Myometrial Calcium and Potassium Channels Play a Pivotal Role in Chromium-Induced Relaxation in Rat Uterus: an In Vitro Study. Biological Trace Element Research. PMID 32034680 DOI: 10.1007/s12011-020-02041-x   
2020 Liu L, Rohacs T. Regulation of the cold-sensing TRPM8 channels by phosphoinositides and G-coupled receptors. Channels (Austin, Tex.). 14: 79-86. PMID 32101066 DOI: 10.1080/19336950.2020.1734266   
2020 Zhao G, Kaplan A, Greiser M, Lederer WJ. The surprising complexity of KATP channel biology and of genetic diseases. The Journal of Clinical Investigation. PMID 32065592 DOI: 10.1172/JCI135759   
2020 Guo Q, Mei S, Xie C, Mi H, Jiang Y, Zhang SD, Tan TW, Fan LH. Reprogramming of sugar transport pathways in Escherichia coli using a permeabilized SecY protein-translocation channel. Biotechnology and Bioengineering. PMID 32048725 DOI: 10.1002/bit.27306   
2020 Yang M, Zhou Y, Wan LL, Ye JZ, Lu HL, Huang X, Xu WX. Luteolin suppresses colonic smooth muscle motility via inhibiting L-type calcium channel currents in mice. General Physiology and Biophysics. 39: 49-58. PMID 32039824 DOI: 10.4149/gpb_2019045   
2020 An JR, Seo MS, Jung HS, Li H, Jung WK, Choi IW, Ha KS, Han ET, Hong SH, Park H, Bae YM, Park WS. Inhibition by the atypical antipsychotic risperidone of voltage-dependent K channels in rabbit coronary arterial smooth muscle cells. European Journal of Pharmacology. 173027. PMID 32084421 DOI: 10.1016/j.ejphar.2020.173027   
2020 Chen Z, Yuan M, Ma Z, Wen J, Wang X, Zhao M, Liu J, Zhang X, Zhao S, Guo L. Significance of Piezo Type Mechanosensitive Ion Channel Component 2 in premature ejaculation: An animal study. Andrology. PMID 32100938 DOI: 10.1111/andr.12779   
2020 Fu D, van der Heijden O, Stanciakova K, Schmidt J, Weckhuysen BM. Disentangling Catalytic Processes of Zeolites within Single Oriented Channels. Angewandte Chemie (International Ed. in English). PMID 32026555 DOI: 10.1002/anie.201916596   
2020 Yehia A, Wei H. Studying Nicotinic Acetylcholine Receptors Using the IonFlux™ Microfluidic-Based Automated Patch-Clamp System with Continuous Perfusion and Fast Solution Exchange. Current Protocols in Pharmacology. 88: e73. PMID 32068960 DOI: 10.1002/cpph.73   
2020 Gill DF, Hansel C. Muscarinic modulation of SK2-type K channels promotes intrinsic plasticity in L2/3 pyramidal neurons of the mouse primary somatosensory cortex. Eneuro. PMID 32005752 DOI: 10.1523/ENEURO.0453-19.2020   
2020 Jeong J, Yoon JS, Lee S, Baek RH. Threshold Voltage Variations Induced by SiGe and SiC of Sub 5-nm Node Silicon Nanosheet Field-Effect Transistors. Journal of Nanoscience and Nanotechnology. 20: 4684-4689. PMID 32126641 DOI: 10.1166/jnn.2020.17799   
2020 Wünsch B, Brömmel K, Maisuls I, Konken CP, Rieke M, Pethő Z, Strassert CA, Maskri S, Koch O, Schwab A. Synthesis of novel small-molecule fluorescently labeled probes for the in vitro imaging of KCa3.1 channels. Angewandte Chemie (International Ed. in English). PMID 32097518 DOI: 10.1002/anie.202001201