| Year |
Citation |
Score |
| 2020 |
Monroe JJ, Tanis KQ, Podtelezhnikov AA, Nguyen T, Mahotka S, Lynch D, Evers R, Palamanda J, Miller R, Pippert T, Cabalu T, Johnson TE, Aslamkhan AG, Kang W, Tamburino AM, et al. Application of a Rat Liver Drug Bioactivation Transcriptional Response Assay Early in Drug Development that informs Chemically Reactive Metabolite formation and Potential for Drug Induced Liver Injury. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 32559301 DOI: 10.1093/Toxsci/Kfaa088 |
0.324 |
|
| 2020 |
Kang W, Podtelezhnikov AA, Tanis KQ, Pacchione S, Su M, Bleicher KB, Wang Z, Laws GM, Griffiths TG, Kuhls MC, Chen Q, Knemeyer I, Marsh DJ, Mitra K, Lebron J, et al. Development and Application of a Transcriptomic Signature of Bioactivation in an Advanced In Vitro Liver Model to Reduce Drug-induced Liver Injury Risk Early in the Pharmaceutical Pipeline. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 32559289 DOI: 10.1093/Toxsci/Kfaa094 |
0.321 |
|
| 2020 |
Podtelezhnikov AA, Monroe JJ, Aslamkhan AG, Pearson K, Qin C, Tamburino AM, Loboda AP, Glaab WE, Sistare FD, Tanis KQ. Quantitative Transcriptional Biomarkers of Xenobiotic Receptor Activation in Rat Liver for The Early Assessment of Drug Safety Liabilities. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 32119089 DOI: 10.1093/Toxsci/Kfaa026 |
0.361 |
|
| 2019 |
Qin C, Aslamkhan AG, Pearson K, Tanis KQ, Podtelezhnikov A, Frank E, Pacchione S, Pippert T, Glaab WE, Sistare FD. AhR Activation in Pharmaceutical Development: Applying Liver Gene Expression Biomarker Thresholds to Identify Doses Associated with Tumorigenic Risks in Rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 31127949 DOI: 10.1093/Toxsci/Kfz125 |
0.347 |
|
| 2018 |
Rothman SM, Tanis KQ, Gandhi P, Malkov V, Marcus J, Pearson M, Stevens R, Gilliland J, Ware C, Mahadomrongkul V, O'Loughlin E, Zeballos G, Smith R, Howell BJ, Klappenbach J, et al. Human Alzheimer's disease gene expression signatures and immune profile in APP mouse models: a discrete transcriptomic view of Aβ plaque pathology. Journal of Neuroinflammation. 15: 256. PMID 30189875 DOI: 10.1186/S12974-018-1265-7 |
0.304 |
|
| 2017 |
Cazanave S, Podtelezhnikov A, Jensen K, Seneshaw M, Kumar DP, Min HK, Santhekadur PK, Banini B, Mauro AG, M Oseini A, Vincent R, Tanis KQ, Webber AL, Wang L, Bedossa P, et al. The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease. Scientific Reports. 7: 17193. PMID 29222421 DOI: 10.1038/S41598-017-17370-6 |
0.327 |
|
| 2016 |
Tanis KQ, Podtelezhnikov AA, Blackman SC, Hing J, Railkar RA, Lunceford J, Klappenbach JA, Wei B, Harman A, Camargo LM, Shah S, Finney EM, Hardwick JS, Loboda A, Watters J, et al. An Accessible Pharmacodynamic Transcriptional Biomarker for Notch Target Engagement. Clinical Pharmacology and Therapeutics. PMID 26765077 DOI: 10.1002/Cpt.335 |
0.312 |
|
| 2015 |
Marcus JN, Tanis K, Pearson M, Wang X, Smith S, Howell B, Gustafson E, Winrow CJ. Genome-wide transcriptional profiles of Alzheimer’s disease mouse models and comparison to human gene expression Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.06.546 |
0.303 |
|
| 2012 |
Nikonova EV, Xiong Y, Tanis KQ, Dawson VL, Vogel RL, Finney EM, Stone DJ, Reynolds IJ, Kern JT, Dawson TM. Transcriptional responses to loss or gain of function of the leucine-rich repeat kinase 2 (LRRK2) gene uncover biological processes modulated by LRRK2 activity. Human Molecular Genetics. 21: 163-74. PMID 21972245 DOI: 10.1093/Hmg/Ddr451 |
0.364 |
|
| 2012 |
Voleti B, Tanis KQ, Newton SS, Duman RS. Analysis of target genes regulated by chronic electroconvulsive therapy reveals role for Fzd6 in depression. Biological Psychiatry. 71: 51-8. PMID 21937024 DOI: 10.1016/J.Biopsych.2011.08.004 |
0.312 |
|
| 2011 |
Podtelezhnikov AA, Tanis KQ, Nebozhyn M, Ray WJ, Stone DJ, Loboda AP. Molecular insights into the pathogenesis of Alzheimer's disease and its relationship to normal aging. Plos One. 6: e29610. PMID 22216330 DOI: 10.1371/Journal.Pone.0029610 |
0.339 |
|
| 2010 |
Blackman SC, Podtelezhnikov A, Railkar RA, Loboda A, Tanis K, Klappenbach JA, Watters J, Iannone R, Herman G, Bergstrom DA. Abstract 26: Notch pathway inhibition with MK-0752 leads to dose- and time-dependent transcriptional alterations in proliferation, PI3K, andWntpathway genes in plucked human hair follicles Cancer Research. 70: 26-26. DOI: 10.1158/1538-7445.Am10-26 |
0.312 |
|
| 2009 |
Blackman SC, Klappenbach JA, Railkar RA, Tanis K, Podtelezhnikov A, Loboda A, Dai X, Hing J, Stone J, Harman A, Hardwick J, Iannone R, Bergstrom D. Abstract B41: Identification of a time‐ and dose‐responsive transcriptional signature of Notch pathway inhibition in plucked human hair follicles following exposure to the gamma‐secretase inhibitor MK‐0752 Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-B41 |
0.32 |
|
| 2008 |
Cao X, Tanis KQ, Koleske AJ, Colicelli J. Enhancement of ABL kinase catalytic efficiency by a direct binding regulator is independent of other regulatory mechanisms. The Journal of Biological Chemistry. 283: 31401-7. PMID 18796434 DOI: 10.1074/Jbc.M804002200 |
0.536 |
|
| 2008 |
Tanis KQ, Duman RS, Newton SS. CREB binding and activity in brain: regional specificity and induction by electroconvulsive seizure. Biological Psychiatry. 63: 710-20. PMID 17936724 DOI: 10.1016/J.Biopsych.2007.08.003 |
0.335 |
|
| 2007 |
Tanis KQ, Duman RS. Intracellular signaling pathways pave roads to recovery for mood disorders. Annals of Medicine. 39: 531-44. PMID 17852035 DOI: 10.1080/07853890701483270 |
0.309 |
|
| 2003 |
Tanis KQ, Veach D, Duewel HS, Bornmann WG, Koleske AJ. Two distinct phosphorylation pathways have additive effects on Abl family kinase activation. Molecular and Cellular Biology. 23: 3884-96. PMID 12748290 DOI: 10.1128/Mcb.23.11.3884-3896.2003 |
0.53 |
|
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