| Year |
Citation |
Score |
| 2023 |
Wang H, Chen R, Xiao L, Kumar M, Acevedo-Cintrón J, Siuda J, Koziorowski D, Wszolek ZK, Dawson VL, Dawson TM. Defects in Mitochondrial Biogenesis Drive Mitochondrial Alterations in PINK1-deficient Human Dopamine Neurons. Biorxiv : the Preprint Server For Biology. PMID 37425943 DOI: 10.1101/2023.06.23.546087 |
0.51 |
|
| 2023 |
Gharagozloo M, Galleguillos D, Jank L, Sotirchos ES, Smith MD, Garton T, Kumar S, Hussein O, Potluri S, Taylor M, Siu C, Mace JW, Dawson T, Dawson VL, Lee S, et al. The Effects of NLY01, a Novel Glucagon-Like Peptide-1 Receptor Agonist, on Cuprizone-Induced Demyelination and Remyelination: Challenges and Future Perspectives. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 37296356 DOI: 10.1007/s13311-023-01390-4 |
0.416 |
|
| 2023 |
Chen C, Kumbhar R, Wang H, Yang X, Gadhave K, Rastegar C, Kimura Y, Behensky A, Katakam S, Jeong D, Wang L, Wang A, Chen R, Zhang S, Jin L, ... ... Dawson TM, et al. Pathological Tau transmission initiated by binding lymphocyte-activation gene 3. Biorxiv : the Preprint Server For Biology. PMID 37293032 DOI: 10.1101/2023.05.16.541015 |
0.683 |
|
| 2023 |
Vitale I, Pietrocola F, Guilbaud E, Aaronson SA, Abrams JM, Adam D, Agostini M, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Aqeilan RI, Arama E, Baehrecke EH, ... ... Dawson TM, et al. Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell Death and Differentiation. PMID 37100955 DOI: 10.1038/s41418-023-01153-w |
0.569 |
|
| 2023 |
Serey-Gaut M, Cortes M, Makrythanasis P, Suri M, Taylor AMR, Sullivan JA, Asleh AN, Mitra J, Dar MA, McNamara A, Shashi V, Dugan S, Song X, Rosenfeld JA, Cabrol C, ... ... Dawson TM, et al. Bi-allelic TTI1 variants cause an autosomal-recessive neurodevelopmental disorder with microcephaly. American Journal of Human Genetics. PMID 36724785 DOI: 10.1016/j.ajhg.2023.01.006 |
0.419 |
|
| 2023 |
Yazar V, Dawson VL, Dawson TM, Kang SU. DNA Methylation Signature of Aging: Potential Impact on the Pathogenesis of Parkinson's Disease. Journal of Parkinson's Disease. PMID 36710687 DOI: 10.3233/JPD-223517 |
0.465 |
|
| 2023 |
Karuppagounder SS, Wang H, Kelly T, Rush R, Nguyen R, Bisen S, Yamashita Y, Sloan N, Dang B, Sigmon A, Lee HW, Marino Lee S, Watkins L, Kim E, Brahmachari S, ... ... Dawson TM, et al. The c-Abl inhibitor IkT-148009 suppresses neurodegeneration in mouse models of heritable and sporadic Parkinson's disease. Science Translational Medicine. 15: eabp9352. PMID 36652533 DOI: 10.1126/scitranslmed.abp9352 |
0.549 |
|
| 2022 |
Jang Y, Pletnikova O, Troncoso JC, Pantelyat AY, Dawson TM, Rosenthal LS, Na CH. Mass spectrometry-based proteomics analysis of human substantia nigra from Parkinson's disease patients identifies multiple pathways potentially involved in the disease. Molecular & Cellular Proteomics : McP. 100452. PMID 36423813 DOI: 10.1016/j.mcpro.2022.100452 |
0.319 |
|
| 2022 |
Patel J, Panicker N, Dawson VL, Dawson TM. Cell Biology of Parkin: Clues to the Development of New Therapeutics for Parkinson's Disease. Cns Drugs. 36: 1249-1267. PMID 36378485 DOI: 10.1007/s40263-022-00973-7 |
0.751 |
|
| 2022 |
Scott L, Karuppagounder SS, Neifert S, Kang BG, Wang H, Dawson VL, Dawson TM. The absence of Parkin does not promote dopamine or mitochondrial dysfunction in PolgA mitochondrial mutator mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 36280265 DOI: 10.1523/JNEUROSCI.0545-22.2022 |
0.507 |
|
| 2022 |
Biswas D, Dawson VL, Dawson TM. Pharmacologic inhibition of MIF nuclease: A new treatment paradigm to treat cell death. Clinical and Translational Medicine. 12: e1044. PMID 36125899 DOI: 10.1002/ctm2.1044 |
0.771 |
|
| 2022 |
Gao J, Mewborne QT, Girdhar A, Sheth U, Coyne AN, Punathil R, Kang BG, Dasovich M, Veire A, DeJesus Hernandez M, Liu S, Shi Z, Dafinca R, Fouquerel E, Talbot K, ... ... Dawson TM, et al. Poly(ADP-ribose) promotes toxicity of arginine-rich dipeptide repeat proteins. Science Translational Medicine. 14: eabq3215. PMID 36103513 DOI: 10.1126/scitranslmed.abq3215 |
0.437 |
|
| 2022 |
Kam TI, Park H, Chou SC, Van Vranken JG, Mittenbühler MJ, Kim H, A M, Choi YR, Biswas D, Wang J, Shin Y, Loder A, Karuppagounder SS, Wrann CD, Dawson VL, ... ... Dawson TM, et al. Amelioration of pathologic α-synuclein-induced Parkinson's disease by irisin. Proceedings of the National Academy of Sciences of the United States of America. 119: e2204835119. PMID 36044549 DOI: 10.1073/pnas.2204835119 |
0.817 |
|
| 2022 |
Umanah GKE, Abalde-Atristain L, Khan MR, Mitra J, Dar MA, Chang M, Tangella K, McNamara A, Bennett S, Chen R, Aggarwal V, Cortes M, Worley PF, Ha T, Dawson TM, et al. AAA + ATPase Thorase inhibits mTOR signaling through the disassembly of the mTOR complex 1. Nature Communications. 13: 4836. PMID 35977929 DOI: 10.1038/s41467-022-32365-2 |
0.78 |
|
| 2022 |
Panicker N, Kam TI, Wang H, Neifert S, Chou SC, Kumar M, Brahmachari S, Jhaldiyal A, Hinkle JT, Akkentli F, Mao X, Xu E, Karuppagounder SS, Hsu ET, Kang SU, ... ... Dawson TM, et al. Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson's disease. Neuron. PMID 35654037 DOI: 10.1016/j.neuron.2022.05.009 |
0.835 |
|
| 2022 |
Park H, Kam TI, Peng H, Chou SC, Mehrabani-Tabari AA, Song JJ, Yin X, Karuppagounder SS, Umanah GK, Rao AVS, Choi Y, Aggarwal A, Chang S, Kim H, Byun J, ... ... Dawson TM, et al. PAAN/MIF nuclease inhibition prevents neurodegeneration in Parkinson's disease. Cell. PMID 35545089 DOI: 10.1016/j.cell.2022.04.020 |
0.559 |
|
| 2022 |
Harraz MM, Malla AP, Semenza ER, Shishikura M, Singh M, Hwang Y, Kang IG, Song YJ, Snowman AM, Cortés P, Karuppagounder SS, Dawson TM, Dawson VL, Snyder SH. A high-affinity cocaine binding site associated with the brain acid soluble protein 1. Proceedings of the National Academy of Sciences of the United States of America. 119: e2200545119. PMID 35412917 DOI: 10.1073/pnas.2200545119 |
0.745 |
|
| 2022 |
Hinkle JT, Patel J, Panicker N, Karuppagounder SS, Biswas D, Belingon B, Chen R, Brahmachari S, Pletnikova O, Troncoso JC, Dawson VL, Dawson TM. STING mediates neurodegeneration and neuroinflammation in nigrostriatal α-synucleinopathy. Proceedings of the National Academy of Sciences of the United States of America. 119: e2118819119. PMID 35394877 DOI: 10.1073/pnas.2118819119 |
0.827 |
|
| 2022 |
Pirooznia SK, Wang H, Panicker N, Kumar M, Neifert S, Dar MA, Lau E, Kang BG, Redding-Ochoa J, Troncoso JC, Dawson VL, Dawson TM. Deubiquitinase CYLD acts as a negative regulator of dopamine neuron survival in Parkinson's disease. Science Advances. 8: eabh1824. PMID 35363524 DOI: 10.1126/sciadv.abh1824 |
0.779 |
|
| 2022 |
Sterling JK, Kam TI, Guttha S, Park H, Baumann B, Mehrabani-Tabari AA, Schultz H, Anderson B, Alnemri A, Chou SC, Troncoso JC, Dawson VL, Dawson TM, Dunaief JL. Interleukin-6 triggers toxic neuronal iron sequestration in response to pathological α-synuclein. Cell Reports. 38: 110358. PMID 35172141 DOI: 10.1016/j.celrep.2022.110358 |
0.479 |
|
| 2021 |
Chou SC, Aggarwal A, Dawson VL, Dawson TM, Kam TI. Recent advances in preventing neurodegenerative diseases. Faculty Reviews. 10: 81. PMID 35028646 DOI: 10.12703/r/10-81 |
0.491 |
|
| 2021 |
Kim JW, Yin X, Martin I, Xiong Y, Eacker SM, Ingolia NT, Dawson TM, Dawson VL. Dysregulated mRNA Translation in the G2019S LRRK2 and LRRK2 Knock-Out Mouse Brains. Eneuro. PMID 34759048 DOI: 10.1523/ENEURO.0310-21.2021 |
0.809 |
|
| 2021 |
Wyse RK, Stott SRW, Mursaleen L, Matthews H, Dawson VL, Dawson TM. Waiting for PARIS-A Biological Target in Search of a Drug. Journal of Parkinson's Disease. PMID 34744054 DOI: 10.3233/jpd-212945 |
0.474 |
|
| 2021 |
Yazar V, Kang SU, Ha S, Dawson VL, Dawson TM. Integrative genome-wide analysis of dopaminergic neuron-specific PARIS expression in Drosophila dissects recognition of multiple PPAR-γ associated gene regulation. Scientific Reports. 11: 21500. PMID 34728675 DOI: 10.1038/s41598-021-00858-7 |
0.561 |
|
| 2021 |
Pirooznia SK, Rosenthal LS, Dawson VL, Dawson TM. Parkinson Disease: Translating Insights from Molecular Mechanisms to Neuroprotection. Pharmacological Reviews. 73: 33-97. PMID 34663684 DOI: 10.1124/pharmrev.120.000189 |
0.509 |
|
| 2021 |
Seo BA, Kim D, Hwang H, Kim MS, Ma SX, Kwon SH, Kweon SH, Wang H, Yoo JM, Choi S, Kwon SH, Kang SU, Kam TI, Kim K, Karuppagounder SS, ... ... Dawson TM, et al. TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson's disease. Neuron. PMID 34644545 DOI: 10.1016/j.neuron.2021.09.031 |
0.717 |
|
| 2021 |
Kim JJ, Lee SY, Hwang Y, Kim S, Chung JM, Park S, Yoon J, Yun H, Ji JH, Chae S, Cho H, Kim CG, Dawson TM, Kim H, Dawson VL, et al. USP39 promotes non-homologous end-joining repair by poly(ADP-ribose)-induced liquid demixing. Nucleic Acids Research. PMID 34614178 DOI: 10.1093/nar/gkab892 |
0.401 |
|
| 2021 |
Kim H, Shin JY, Jo A, Kim JH, Park S, Choi JY, Kang HC, Dawson VL, Dawson TM, Shin JH, Lee Y. Parkin interacting substrate phosphorylation by c-Abl drives dopaminergic neurodegeneration. Brain : a Journal of Neurology. PMID 34581802 DOI: 10.1093/brain/awab356 |
0.504 |
|
| 2021 |
Lüscher B, Ahel I, Altmeyer M, Ashworth A, Bai P, Chang P, Cohen M, Corda D, Dantzer F, Daugherty MD, Dawson TM, Dawson VL, Deindl S, Fehr AR, Feijs KLH, et al. ADP-ribosyltransferases, an update on function and nomenclature. The Febs Journal. PMID 34323016 DOI: 10.1111/febs.16142 |
0.452 |
|
| 2021 |
Jo A, Lee Y, Kam TI, Kang SU, Neifert S, Karuppagounder SS, Khang R, Kang H, Park H, Chou SC, Oh S, Jiang H, Swing DA, Ham S, Pirooznia S, ... ... Dawson TM, et al. PARIS farnesylation prevents neurodegeneration in models of Parkinson's disease. Science Translational Medicine. 13. PMID 34321320 DOI: 10.1126/scitranslmed.aax8891 |
0.714 |
|
| 2021 |
Gharagozloo M, Smith MD, Sotirchos ES, Jin J, Meyers K, Taylor M, Garton T, Bannon R, Lord HN, Dawson TM, Dawson VL, Lee S, Calabresi PA. Therapeutic Potential of a Novel Glucagon-like Peptide-1 Receptor Agonist, NLY01, in Experimental Autoimmune Encephalomyelitis. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 34260042 DOI: 10.1007/s13311-021-01088-5 |
0.449 |
|
| 2021 |
Kim NS, Ringeling FR, Zhou Y, Nguyen HN, Temme SJ, Lin YT, Eacker S, Dawson VL, Dawson TM, Xiao B, Hsu KS, Canzar S, Li W, Worley P, Christian KM, et al. CYFIP1 Dosages Exhibit Divergent Behavioral Impact via Diametric Regulation of NMDA Receptor Complex Translation in Mouse Models of Psychiatric Disorders. Biological Psychiatry. PMID 34247782 DOI: 10.1016/j.biopsych.2021.04.023 |
0.772 |
|
| 2021 |
Zhang L, Chen C, Fu J, Lilley B, Berlinicke C, Hansen B, Ding D, Wang G, Wang T, Shou D, Ye Y, Mulligan T, Emmerich K, Saxena MT, Hall KR, ... ... Dawson TM, et al. Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa. Elife. 10. PMID 34184634 DOI: 10.7554/eLife.57245 |
0.416 |
|
| 2021 |
Zhang S, Liu YQ, Jia C, Lim YJ, Feng G, Xu E, Long H, Kimura Y, Tao Y, Zhao C, Wang C, Liu Z, Hu JJ, Ma MR, Liu Z, ... ... Dawson TM, et al. Mechanistic basis for receptor-mediated pathological α-synuclein fibril cell-to-cell transmission in Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34172566 DOI: 10.1073/pnas.2011196118 |
0.682 |
|
| 2021 |
Ma SX, Seo BA, Kim D, Xiong Y, Kwon SH, Brahmachari S, Kim S, Kam TI, Nirujogi RS, Kwon SH, Dawson VL, Dawson TM, Pandey A, Na CH, Ko HS. Complement and Coagulation Cascades are Potentially Involved in Dopaminergic Neurodegeneration in α-Synuclein-Based Mouse Models of Parkinson's Disease. Journal of Proteome Research. PMID 34061533 DOI: 10.1021/acs.jproteome.0c01002 |
0.539 |
|
| 2021 |
Koehler RC, Dawson VL, Dawson TM. Targeting Parthanatos in Ischemic Stroke. Frontiers in Neurology. 12: 662034. PMID 34025565 DOI: 10.3389/fneur.2021.662034 |
0.45 |
|
| 2021 |
Park JS, Kam TI, Lee S, Park H, Oh Y, Kwon SH, Song JJ, Kim D, Kim H, Jhaldiyal A, Na DH, Lee KC, Park EJ, Pomper MG, Pletnikova O, ... ... Dawson TM, et al. Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer's disease. Acta Neuropathologica Communications. 9: 78. PMID 33902708 DOI: 10.1186/s40478-021-01180-z |
0.786 |
|
| 2021 |
Yin X, Kim JW, Liu S, Dawson TM, Dawson VL. Protocol for measurement of calcium dysregulation in human induced pluripotent stem cell-derived dopaminergic neurons. Star Protocols. 2: 100405. PMID 33855307 DOI: 10.1016/j.xpro.2021.100405 |
0.492 |
|
| 2021 |
Liu S, Zhou M, Ruan Z, Wang Y, Chang C, Sasaki M, Rajaram V, Lemoff A, Nambiar K, Wang JE, Hatanpaa KJ, Luo W, Dawson TM, Dawson VL, Wang Y. AIF3 splicing switch triggers neurodegeneration. Molecular Neurodegeneration. 16: 25. PMID 33853653 DOI: 10.1186/s13024-021-00442-7 |
0.461 |
|
| 2021 |
Gu H, Yang X, Mao X, Xu E, Qi C, Wang H, Brahmachari S, York B, Sriparna M, Li A, Chang M, Patel P, Dawson VL, Dawson TM. Lymphocyte Activation Gene 3 (Lag3) Contributes to α-Synucleinopathy in α-Synuclein Transgenic Mice. Frontiers in Cellular Neuroscience. 15: 656426. PMID 33776654 DOI: 10.3389/fncel.2021.656426 |
0.735 |
|
| 2021 |
Panicker N, Ge P, Dawson VL, Dawson TM. The cell biology of Parkinson's disease. The Journal of Cell Biology. 220. PMID 33749710 DOI: 10.1083/jcb.202012095 |
0.833 |
|
| 2021 |
Fais M, Sanna G, Galioto M, Nguyen TTD, Trần MUT, Sini P, Carta F, Turrini F, Xiong Y, Dawson TM, Dawson VL, Crosio C, Iaccarino C. LRRK2 Modulates the Exocyst Complex Assembly by Interacting with Sec8. Cells. 10. PMID 33498474 DOI: 10.3390/cells10020203 |
0.513 |
|
| 2021 |
Liu Y, Mao Y, Xu E, Jia H, Zhang S, Dawson VL, Dawson TM, Li Y, Zheng Z, He W, Mao X. Nanozyme scavenging ROS for prevention of pathologic α-synuclein transmission in Parkinson’s disease Nano Today. 36: 101027. DOI: 10.1016/j.nantod.2020.101027 |
0.456 |
|
| 2020 |
Jia L, Liu Y, Wang W, Wang Y, Liu H, Liu F, Chen R, Dawson VL, Dawson TM, Lu F, Liu L, Wang Y, Mao X. Molecular Mediation of Prion-like α-Synuclein Fibrillation from Toxic PFFs to Nontoxic Species. Acs Applied Bio Materials. 3: 6096-6102. PMID 35021742 DOI: 10.1021/acsabm.0c00684 |
0.703 |
|
| 2020 |
Yin X, Dawson TM, Dawson VL. Integration of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Neurons into Rat Brain Circuits. Bio-Protocol. 10: e3746. PMID 33659406 DOI: 10.21769/BioProtoc.3746 |
0.47 |
|
| 2020 |
Henrich MT, Geibl FF, Lakshminarasimhan H, Stegmann A, Giasson BI, Mao X, Dawson VL, Dawson TM, Oertel WH, Surmeier DJ. Determinants of seeding and spreading of α-synuclein pathology in the brain. Science Advances. 6. PMID 33177086 DOI: 10.1126/sciadv.abc2487 |
0.708 |
|
| 2020 |
Umanah GKE, Ghasemi M, Yin X, Chang M, Kim JW, Zhang J, Ma E, Scarffe LA, Lee YI, Chen R, Tangella K, McNamara A, Abalde-Atristain L, Dar MA, Bennett S, ... ... Dawson TM, et al. AMPA Receptor Surface Expression Is Regulated by S-Nitrosylation of Thorase and Transnitrosylation of NSF. Cell Reports. 33: 108329. PMID 33147468 DOI: 10.1016/j.celrep.2020.108329 |
0.787 |
|
| 2020 |
Kim JW, Yin X, Jhaldiyal A, Khan MR, Martin I, Xie Z, Perez-Rosello T, Kumar M, Abalde-Atristain L, Xu J, Chen L, Eacker SM, Surmeier DJ, Ingolia NT, Dawson TM, et al. Defects in mRNA Translation in LRRK2-Mutant hiPSC-Derived Dopaminergic Neurons Lead to Dysregulated Calcium Homeostasis. Cell Stem Cell. PMID 32846140 DOI: 10.1016/J.Stem.2020.08.002 |
0.817 |
|
| 2020 |
Kumar M, Acevedo-Cintrón J, Jhaldiyal A, Wang H, Andrabi SA, Eacker S, Karuppagounder SS, Brahmachari S, Chen R, Kim H, Ko HS, Dawson VL, Dawson TM. Defects in Mitochondrial Biogenesis Drive Mitochondrial Alterations in PARKIN-Deficient Human Dopamine Neurons. Stem Cell Reports. PMID 32795422 DOI: 10.1016/J.Stemcr.2020.07.013 |
0.803 |
|
| 2020 |
Kam TI, Hinkle JT, Dawson TM, Dawson VL. Microglia and astrocyte dysfunction in parkinson's disease. Neurobiology of Disease. 105028. PMID 32736085 DOI: 10.1016/J.Nbd.2020.105028 |
0.592 |
|
| 2020 |
Wan YW, Al-Ouran R, Mangleburg CG, Perumal TM, Lee TV, Allison K, Swarup V, Funk CC, Gaiteri C, Allen M, Wang M, Neuner SM, Kaczorowski CC, Philip VM, Howell GR, ... ... Dawson TM, et al. Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. Cell Reports. 32: 107908. PMID 32668255 DOI: 10.1016/J.Celrep.2020.107908 |
0.509 |
|
| 2020 |
Na CH, Sathe G, Rosenthal LS, Moghekar AR, Dawson VL, Dawson TM, Pandey A. Development of a novel method for the quantification of tyrosine 39 phosphorylated α- and β-synuclein in human cerebrospinal fluid. Clinical Proteomics. 17: 13. PMID 32390785 DOI: 10.1186/S12014-020-09277-8 |
0.573 |
|
| 2020 |
Park H, Kam TI, Dawson TM, Dawson VL. Poly (ADP-ribose) (PAR)-dependent cell death in neurodegenerative diseases. International Review of Cell and Molecular Biology. 353: 1-29. PMID 32381174 DOI: 10.1016/Bs.Ircmb.2019.12.009 |
0.59 |
|
| 2020 |
Agarwal A, Park S, Ha S, Kwon JS, Khan MR, Kang BG, Dawson TM, Dawson VL, Andrabi SA, Kang SU. Quantitative mass spectrometric analysis of the mouse cerebral cortex after ischemic stroke. Plos One. 15: e0231978. PMID 32315348 DOI: 10.1371/Journal.Pone.0231978 |
0.491 |
|
| 2020 |
Ge P, Dawson VL, Dawson TM. PINK1 and Parkin mitochondrial quality control: a source of regional vulnerability in Parkinson's disease. Molecular Neurodegeneration. 15: 20. PMID 32169097 DOI: 10.1186/S13024-020-00367-7 |
0.736 |
|
| 2020 |
Pirooznia SK, Yuan C, Khan MR, Karuppagounder SS, Wang L, Xiong Y, Kang SU, Lee Y, Dawson VL, Dawson TM. PARIS induced defects in mitochondrial biogenesis drive dopamine neuron loss under conditions of parkin or PINK1 deficiency. Molecular Neurodegeneration. 15: 17. PMID 32138754 DOI: 10.1186/S13024-020-00363-X |
0.825 |
|
| 2020 |
Panicker N, Kam T, Neifert S, Hinkle J, Mao X, Karuppagounder S, Wang H, Kumar M, Pirooznia S, Pletnikova O, Troncoso J, Dawson VL, Dawson TM. NLRP3 inflammasome activation in dopamine neurons contributes to neurodegeneration in Parkinson’s Disease The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.01881 |
0.807 |
|
| 2020 |
Jia L, Liu Y, Wang W, Wang Y, Liu H, Liu F, Chen R, Dawson VL, Dawson TM, Lu F, Liu L, Wang Y, Mao X. Molecular Mediation of Prion-like α-Synuclein Fibrillation from Toxic PFFs to Nontoxic Species Acs Applied Bio Materials. 3: 6096-6102. DOI: 10.1021/acsabm.0c00684 |
0.411 |
|
| 2019 |
Dawson VL, Dawson TM. Promising disease-modifying therapies for Parkinson's disease. Science Translational Medicine. 11. PMID 31776289 DOI: 10.1126/Scitranslmed.Aba1659 |
0.508 |
|
| 2019 |
Blauwendraat C, Reed X, Krohn L, Heilbron K, Bandres-Ciga S, Tan M, Gibbs JR, Hernandez DG, Kumaran R, Langston R, Bonet-Ponce L, Alcalay RN, Hassin-Baer S, Greenbaum L, Iwaki H, ... ... Dawson TM, et al. Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia. Brain : a Journal of Neurology. PMID 31755958 DOI: 10.1093/Brain/Awz350 |
0.336 |
|
| 2019 |
Yin X, Xu JC, Cho GS, Kwon C, Dawson TM, Dawson VL. Neurons Derived from Human Induced Pluripotent Stem Cells Integrate into Rat Brain Circuits and Maintain both Excitatory and Inhibitory Synaptic Activities. Eneuro. PMID 31413152 DOI: 10.1523/ENEURO.0148-19.2019 |
0.589 |
|
| 2019 |
Jin J, Smith MD, Kersbergen CJ, Kam TI, Viswanathan M, Martin K, Dawson TM, Dawson VL, Zack DJ, Whartenby K, Calabresi PA. Glial pathology and retinal neurotoxicity in the anterior visual pathway in experimental autoimmune encephalomyelitis. Acta Neuropathologica Communications. 7: 125. PMID 31366377 DOI: 10.1186/S40478-019-0767-6 |
0.512 |
|
| 2019 |
Kim S, Kwon SH, Kam TI, Panicker N, Karuppagounder SS, Lee S, Lee JH, Kim WR, Kook M, Foss CA, Shen C, Lee H, Kulkarni S, Pasricha PJ, Lee G, ... ... Dawson TM, et al. Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson's Disease. Neuron. PMID 31255487 DOI: 10.1016/J.Neuron.2019.05.035 |
0.801 |
|
| 2019 |
Brahmachari S, Lee S, Kim S, Yuan C, Karuppagounder SS, Ge P, Shi R, Kim EJ, Liu A, Kim D, Quintin S, Jiang H, Kumar M, Yun SP, Kam TI, ... ... Dawson TM, et al. Parkin interacting substrate zinc finger protein 746 is a pathological mediator in Parkinson's disease. Brain : a Journal of Neurology. PMID 31237944 DOI: 10.1093/Brain/Awz172 |
0.816 |
|
| 2019 |
Hinkle JT, Dawson VL, Dawson TM. The A1 astrocyte paradigm: New avenues for pharmacological intervention in neurodegeneration. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 31136698 DOI: 10.1002/Mds.27718 |
0.564 |
|
| 2019 |
Panicker N, Sarkar S, Harischandra DS, Neal M, Kam TI, Jin H, Saminathan H, Langley M, Charli A, Samidurai M, Rokad D, Ghaisas S, Pletnikova O, Dawson VL, Dawson TM, et al. Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia. The Journal of Experimental Medicine. PMID 31036561 DOI: 10.1084/Jem.20182191 |
0.817 |
|
| 2019 |
Sabir MS, Blauwendraat C, Ahmed S, Serrano GE, Beach TG, Perkins M, Rice AC, Masliah E, Morris CM, Pihlstrom L, Pantelyat A, Resnick SM, Cookson MR, Hernandez DG, Albert M, ... Dawson TM, et al. Assessment of APOE in atypical parkinsonism syndromes. Neurobiology of Disease. PMID 30798004 DOI: 10.1016/J.Nbd.2019.02.016 |
0.305 |
|
| 2018 |
Xue Y, Zhan X, Sun S, Karuppagounder SS, Xia S, Dawson VL, Dawson TM, Laterra J, Zhang J, Ying M. Synthetic mRNAs Drive Highly Efficient iPS Cell Differentiation to Dopaminergic Neurons. Stem Cells Translational Medicine. PMID 30387318 DOI: 10.1002/Sctm.18-0036 |
0.806 |
|
| 2018 |
Kam TI, Mao X, Park H, Chou SC, Karuppagounder SS, Umanah GE, Yun SP, Brahmachari S, Panicker N, Chen R, Andrabi SA, Qi C, Poirier GG, Pletnikova O, Troncoso JC, ... ... Dawson TM, et al. Poly(ADP-ribose) drives pathologic α-synuclein neurodegeneration in Parkinson's disease. Science (New York, N.Y.). 362. PMID 30385548 DOI: 10.1126/Science.Aat8407 |
0.822 |
|
| 2018 |
Dawson TM, Golde TE, Lagier-Tourenne C. Animal models of neurodegenerative diseases. Nature Neuroscience. 21: 1370-1379. PMID 30250265 DOI: 10.1038/S41593-018-0236-8 |
0.324 |
|
| 2018 |
Hinkle JT, Perepezko K, Mills KA, Mari Z, Butala A, Dawson TM, Pantelyat A, Rosenthal LS, Pontone GM. Dopamine transporter availability reflects gastrointestinal dysautonomia in early Parkinson disease. Parkinsonism & Related Disorders. PMID 30146185 DOI: 10.1016/J.Parkreldis.2018.08.010 |
0.386 |
|
| 2018 |
Chen-Plotkin AS, Albin R, Alcalay R, Babcock D, Bajaj V, Bowman D, Buko A, Cedarbaum J, Chelsky D, Cookson MR, Dawson TM, Dewey R, Foroud T, Frasier M, German D, et al. Finding useful biomarkers for Parkinson's disease. Science Translational Medicine. 10. PMID 30111645 DOI: 10.1126/Scitranslmed.Aam6003 |
0.332 |
|
| 2018 |
Yun SP, Kam TI, Panicker N, Kim S, Oh Y, Park JS, Kwon SH, Park YJ, Karuppagounder SS, Park H, Kim S, Oh N, Kim NA, Lee S, Brahmachari S, ... ... Dawson TM, et al. Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease. Nature Medicine. PMID 29892066 DOI: 10.1038/S41591-018-0051-5 |
0.814 |
|
| 2018 |
Hinkle JT, Perepezko K, Bakker CC, Broen MPG, Chin K, Dawson TM, Johnson V, Mari Z, Marvel CL, Mills KA, Pantelyat A, Pletnikova O, Rosenthal LS, Shepard MD, Stevens DA, et al. Onset and Remission of Psychosis in Parkinson's Disease: Pharmacologic and Motoric Markers. Movement Disorders Clinical Practice. 5: 31-38. PMID 29756003 DOI: 10.1002/Mdc3.12550 |
0.386 |
|
| 2018 |
Piard J, Essien Umanah GK, Harms FL, Abalde-Atristain L, Amram D, Chang M, Chen R, Alawi M, Salpietro V, Rees MI, Chung SK, Houlden H, Verloes A, Dawson TM, Dawson VL, et al. Reply: ATAD1 encephalopathy and stiff baby syndrome: a recognizable clinical presentation. Brain : a Journal of Neurology. PMID 29659731 DOI: 10.1093/Brain/Awy100 |
0.75 |
|
| 2018 |
Zhang J, Yang J, Wang H, Sherbini O, Keuss MJ, Umanah GK, Pai EL, Chi Z, Paldanius KM, He W, Wang H, Andrabi SA, Dawson TM, Dawson VL. The AAA + ATPase Thorase is neuroprotective against ischemic injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X18769770. PMID 29658368 DOI: 10.1177/0271678X18769770 |
0.639 |
|
| 2018 |
Jouroukhin Y, Kageyama Y, Misheneva V, Shevelkin A, Andrabi S, Prandovszky E, Yolken RH, Dawson VL, Dawson TM, Aja S, Sesaki H, Pletnikov MV. DISC1 regulates lactate metabolism in astrocytes: implications for psychiatric disorders. Translational Psychiatry. 8: 76. PMID 29643356 DOI: 10.1038/S41398-018-0123-9 |
0.522 |
|
| 2018 |
Jeong GR, Jang EH, Bae JR, Jun S, Kang HC, Park CH, Shin JH, Yamamoto Y, Tanaka-Yamamoto K, Dawson VL, Dawson TM, Hur EM, Lee BD. Dysregulated phosphorylation of Rab GTPases by LRRK2 induces neurodegeneration. Molecular Neurodegeneration. 13: 8. PMID 29439717 DOI: 10.1186/S13024-018-0240-1 |
0.563 |
|
| 2018 |
Dawson TM, Dawson VL. Nitric Oxide Signaling in Neurodegeneration and Cell Death. Advances in Pharmacology (San Diego, Calif.). 82: 57-83. PMID 29413528 DOI: 10.1016/Bs.Apha.2017.09.003 |
0.581 |
|
| 2018 |
Piard J, Umanah GKE, Harms FL, Abalde-Atristain L, Amram D, Chang M, Chen R, Alawi M, Salpietro V, Rees MI, Chung SK, Houlden H, Verloes A, Dawson TM, Dawson VL, et al. A homozygous ATAD1 mutation impairs postsynaptic AMPA receptor trafficking and causes a lethal encephalopathy. Brain : a Journal of Neurology. PMID 29390050 DOI: 10.1093/Brain/Awx377 |
0.799 |
|
| 2018 |
Xiong Y, Neifert S, Karuppagounder SS, Liu Q, Stankowski JN, Lee BD, Ko HS, Lee Y, Grima JC, Mao X, Jiang H, Kang SU, Swing DA, Iacovitti L, Tessarollo L, ... Dawson TM, et al. Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 29386392 DOI: 10.1073/Pnas.1712648115 |
0.822 |
|
| 2018 |
Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, ... ... Dawson TM, et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death and Differentiation. PMID 29362479 DOI: 10.1038/S41418-017-0012-4 |
0.486 |
|
| 2018 |
Kim S, Yun SP, Lee S, Umanah GE, Bandaru VVR, Yin X, Rhee P, Karuppagounder SS, Kwon SH, Lee H, Mao X, Kim D, Pandey A, Lee G, Dawson VL, ... Dawson TM, et al. GBA1 deficiency negatively affects physiological α-synuclein tetramers and related multimers. Proceedings of the National Academy of Sciences of the United States of America. PMID 29311330 DOI: 10.1073/Pnas.1700465115 |
0.812 |
|
| 2018 |
Yun SP, Kim D, Kim S, Kim S, Karuppagounder SS, Kwon SH, Lee S, Kam TI, Lee S, Ham S, Park JH, Dawson VL, Dawson TM, Lee Y, Ko HS. α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism. Molecular Neurodegeneration. 13: 1. PMID 29310663 DOI: 10.1186/S13024-017-0233-5 |
0.824 |
|
| 2018 |
ANDO M, FIESEL FC, HUDEC R, CAULFIELD TR, OGAKI K, GÓRKA-SKOCZYLAS P, KOZIOROWSKI D, FRIEDMAN A, CHEN L, DAWSON VL, DAWSON TM, BU G, ROSS OA, WSZOLEK ZK, SPRINGER W. The PINK1 p.I368N Mutation Affects Protein Stability and Kinase Activity with Its Structural Change Juntendo Medical Journal. 64: 17-30. DOI: 10.14789/Jmj.2018.64.Jmjjmj17-R10 |
0.474 |
|
| 2017 |
Martos SN, Li T, Ramos RB, Lou D, Dai H, Xu JC, Gao G, Gao Y, Wang Q, An C, Zhang X, Jia Y, Dawson VL, Dawson TM, Ji H, et al. Two approaches reveal a new paradigm of 'switchable or genetics-influenced allele-specific DNA methylation' with potential in human disease. Cell Discovery. 3: 17038. PMID 29387450 DOI: 10.1038/Celldisc.2017.38 |
0.576 |
|
| 2017 |
Kaji S, Maki T, Kinoshita H, Uemura N, Ayaki T, Kawamoto Y, Furuta T, Urushitani M, Hasegawa M, Kinoshita Y, Ono Y, Mao X, Quach TH, Iwai K, Dawson VL, ... Dawson TM, et al. Pathological Endogenous α-Synuclein Accumulation in Oligodendrocyte Precursor Cells Potentially Induces Inclusions in Multiple System Atrophy. Stem Cell Reports. PMID 29337114 DOI: 10.1016/J.Stemcr.2017.12.001 |
0.684 |
|
| 2017 |
Umanah GKE, Pignatelli M, Yin X, Chen R, Crawford J, Neifert S, Scarffe L, Behensky AA, Guiberson N, Chang M, Ma E, Kim JW, Castro CC, Mao X, Chen L, ... ... Dawson TM, et al. Thorase variants are associated with defects in glutamatergic neurotransmission that can be rescued by Perampanel. Science Translational Medicine. 9. PMID 29237760 DOI: 10.1126/Scitranslmed.Aah4985 |
0.681 |
|
| 2017 |
Hinkle JT, Perepezko K, Rosenthal LS, Mills KA, Pantelyat A, Mari Z, Tochen L, Bang JY, Gudavalli M, Yoritomo N, Butala A, Bakker CC, Johnson V, Moukheiber E, Dawson TM, et al. Markers of impaired motor and cognitive volition in Parkinson's disease: Correlates of dopamine dysregulation syndrome, impulse control disorder, and dyskinesias. Parkinsonism & Related Disorders. PMID 29198499 DOI: 10.1016/J.Parkreldis.2017.11.338 |
0.377 |
|
| 2017 |
Brahmachari S, Karuppagounder SS, Ge P, Lee S, Dawson VL, Dawson TM, Ko HS. c-Abl and Parkinson's Disease: Mechanisms and Therapeutic Potential. Journal of Parkinson's Disease. 7: 589-601. PMID 29103051 DOI: 10.3233/Jpd-171191 |
0.813 |
|
| 2017 |
Sulzer D, Alcalay RN, Garretti F, Cote L, Kanter E, Agin-Liebes J, Liong C, McMurtrey C, Hildebrand WH, Mao X, Dawson VL, Dawson TM, Oseroff C, Pham J, Sidney J, et al. Erratum: T cells from patients with Parkinson's disease recognize α-synuclein peptides. Nature. 549: 292. PMID 28905919 DOI: 10.1038/nature23896 |
0.651 |
|
| 2017 |
McCall MN, Kim MS, Adil M, Patil AH, Lu Y, Mitchell CJ, Leal-Rojas P, Xu J, Kumar M, Dawson VL, Dawson TM, Baras AS, Rosenberg AZ, Arking DE, Burns KH, et al. Toward the human cellular microRNAome. Genome Research. PMID 28877962 DOI: 10.1101/Gr.222067.117 |
0.583 |
|
| 2017 |
Panicker N, Dawson VL, Dawson TM. Activation mechanisms of the E3 ubiquitin ligase parkin. The Biochemical Journal. 474: 3075-3086. PMID 28860335 DOI: 10.1042/Bcj20170476 |
0.782 |
|
| 2017 |
Fan J, Dawson TM, Dawson VL. Cell Death Mechanisms of Neurodegeneration. Advances in Neurobiology. 15: 403-425. PMID 28674991 DOI: 10.1007/978-3-319-57193-5_16 |
0.561 |
|
| 2017 |
Gwinn K, David KK, Swanson-Fischer C, Albin R, Hillaire-Clarke CS, Sieber BA, Lungu C, Bowman FD, Alcalay RN, Babcock D, Dawson TM, Dewey RB, Foroud T, German D, Huang X, et al. Parkinson's disease biomarkers: perspective from the NINDS Parkinson's Disease Biomarkers Program. Biomarkers in Medicine. PMID 28644039 DOI: 10.2217/Bmm-2016-0370 |
0.359 |
|
| 2017 |
Sulzer D, Alcalay RN, Garretti F, Cote L, Kanter E, Agin-Liebes J, Liong C, McMurtrey C, Hildebrand WH, Mao X, Dawson VL, Dawson TM, Oseroff C, Pham J, Sidney J, et al. T cells from patients with Parkinson's disease recognize α-synuclein peptides. Nature. PMID 28636593 DOI: 10.1038/Nature22815 |
0.701 |
|
| 2017 |
Hinkle JT, Perepezko K, Bakker CC, Dawson TM, Johnson V, Mari Z, Marvel CL, Mills KA, Pantelyat A, Pletnikova O, Rosenthal LS, Shepard MD, Stevens DA, Troncoso JC, Wang J, et al. Domain-specific cognitive impairment in non-demented Parkinson's disease psychosis. International Journal of Geriatric Psychiatry. PMID 28509347 DOI: 10.1002/Gps.4736 |
0.305 |
|
| 2017 |
Scott L, Dawson VL, Dawson TM. Trumping neurodegeneration: Targeting common pathways regulated by autosomal recessive Parkinson's disease genes. Experimental Neurology. PMID 28445716 DOI: 10.1016/J.Expneurol.2017.04.008 |
0.607 |
|
| 2017 |
Ando M, Fiesel FC, Hudec R, Caulfield TR, Ogaki K, Górka-Skoczylas P, Koziorowski D, Friedman A, Chen L, Dawson VL, Dawson TM, Bu G, Ross OA, Wszolek ZK, Springer W. The PINK1 p.I368N mutation affects protein stability and ubiquitin kinase activity. Molecular Neurodegeneration. 12: 32. PMID 28438176 DOI: 10.1186/S13024-017-0174-Z |
0.555 |
|
| 2017 |
Puschmann A, Fiesel FC, Caulfield TR, Hudec R, Ando M, Truban D, Hou X, Ogaki K, Heckman MG, James ED, Swanberg M, Jimenez-Ferrer I, Hansson O, Opala G, Siuda J, ... ... Dawson TM, et al. Reply: Heterozygous PINK1 p.G411S in rapid eye movement sleep behaviour disorder. Brain : a Journal of Neurology. PMID 28379295 DOI: 10.1093/Brain/Awx077 |
0.421 |
|
| 2017 |
Xiong Y, Dawson TM, Dawson VL. Models of LRRK2-Associated Parkinson's Disease. Advances in Neurobiology. 14: 163-191. PMID 28353284 DOI: 10.1007/978-3-319-49969-7_9 |
0.589 |
|
| 2017 |
Xiong Y, Neifert S, Karuppagounder SS, Stankowski JN, Lee BD, Grima JC, Chen G, Ko HS, Lee Y, Swing D, Tessarollo L, Dawson TM, Dawson VL. Overexpression of Parkinson's Disease-Associated Mutation LRRK2 G2019S in Mouse Forebrain Induces Behavioral Deficits and α-Synuclein Pathology. Eneuro. 4. PMID 28321439 DOI: 10.1523/ENEURO.0004-17.2017 |
0.828 |
|
| 2017 |
Berger NA, Besson VC, Boulares AH, Bürkle A, Chiarugi A, Clark RS, Curtin NJ, Cuzzocrea S, Dawson TM, Dawson VL, Haskó G, Liaudet L, Moroni F, Pacher P, Radermacher P, et al. Opportunities for repurposing of poly(ADP-ribose) polymerase (PARP) inhibitors for the therapy of non-oncological diseases. British Journal of Pharmacology. PMID 28213892 DOI: 10.1111/Bph.13748 |
0.628 |
|
| 2017 |
Ahrens-Nicklas RC, Umanah GK, Sondheimer N, Deardorff MA, Wilkens AB, Conlin LK, Santani AB, Nesbitt A, Juulsola J, Ma E, Dawson TM, Dawson VL, Marsh ED. Precision therapy for a new disorder of AMPA receptor recycling due to mutations in ATAD1. Neurology. Genetics. 3: e130. PMID 28180185 DOI: 10.1212/Nxg.0000000000000130 |
0.488 |
|
| 2017 |
Lee Y, Stevens DA, Kang SU, Jiang H, Lee YI, Ko HS, Scarffe LA, Umanah GE, Kang H, Ham S, Kam TI, Allen K, Brahmachari S, Kim JW, Neifert S, ... ... Dawson TM, et al. PINK1 Primes Parkin-Mediated Ubiquitination of PARIS in Dopaminergic Neuronal Survival. Cell Reports. 18: 918-932. PMID 28122242 DOI: 10.1016/J.Celrep.2016.12.090 |
0.617 |
|
| 2017 |
Pignatelli M, Umanah GK, Ribeiro SP, Chen R, Karuppagounder SS, Yau HJ, Eacker S, Dawson VL, Dawson TM, Bonci A. Synaptic Plasticity onto Dopamine Neurons Shapes Fear Learning. Neuron. 93: 425-440. PMID 28103482 DOI: 10.1016/J.Neuron.2016.12.030 |
0.787 |
|
| 2017 |
Liddelow SA, Guttenplan KA, Clarke LE, Bennett FC, Bohlen CJ, Schirmer L, Bennett ML, Münch AE, Chung WS, Peterson TC, Wilton DK, Frouin A, Napier BA, Panicker N, Kumar M, ... ... Dawson TM, et al. Neurotoxic reactive astrocytes are induced by activated microglia. Nature. PMID 28099414 DOI: 10.1038/Nature21029 |
0.758 |
|
| 2017 |
Dawson TM, Dawson VL. Mitochondrial Mechanisms of Neuronal Cell Death: Potential Therapeutics. Annual Review of Pharmacology and Toxicology. 57: 437-454. PMID 28061689 DOI: 10.1146/Annurev-Pharmtox-010716-105001 |
0.545 |
|
| 2016 |
Wang Y, An R, Umanah GK, Park H, Nambiar K, Eacker SM, Kim B, Bao L, Harraz MM, Chang C, Chen R, Wang JE, Kam TI, Jeong JS, Xie Z, ... ... Dawson TM, et al. A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1. Science (New York, N.Y.). 354. PMID 27846469 DOI: 10.1126/Science.Aad6872 |
0.799 |
|
| 2016 |
Zhang J, Wang H, Sherbini O, Ling-Lin Pai E, Kang SU, Kwon JS, Yang J, He W, Wang H, Eacker SM, Chi Z, Mao X, Xu J, Jiang H, Andrabi SA, ... Dawson TM, et al. High-Content Genome-Wide RNAi Screen Reveals CCR3 as a Key Mediator of Neuronal Cell Death. Eneuro. 3. PMID 27822494 DOI: 10.1523/ENEURO.0185-16.2016 |
0.803 |
|
| 2016 |
Puschmann A, Fiesel FC, Caulfield TR, Hudec R, Ando M, Truban D, Hou X, Ogaki K, Heckman MG, James ED, Swanberg M, Jimenez-Ferrer I, Hansson O, Opala G, Siuda J, ... ... Dawson TM, et al. Heterozygous PINK1 p.G411S increases risk of Parkinson's disease via a dominant-negative mechanism. Brain : a Journal of Neurology. PMID 27807026 DOI: 10.1093/Brain/Aww261 |
0.539 |
|
| 2016 |
Mao X, Ou MT, Karuppagounder SS, Kam TI, Yin X, Xiong Y, Ge P, Umanah GE, Brahmachari S, Shin JH, Kang HC, Zhang J, Xu J, Chen R, Park H, ... ... Dawson TM, et al. Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3. Science (New York, N.Y.). 353. PMID 27708076 DOI: 10.1126/Science.Aah3374 |
0.804 |
|
| 2016 |
Mills KA, Mari Z, Bakker C, Johnson V, Pontone GM, Pantelyat A, Troncoso JC, Pletnikova O, Dawson TM, Rosenthal LS. Gait function and locus coeruleus Lewy body pathology in 51 Parkinson's disease patients. Parkinsonism & Related Disorders. PMID 27693194 DOI: 10.1016/J.Parkreldis.2016.09.024 |
0.406 |
|
| 2016 |
Jiang H, Kang SU, Zhang S, Karuppagounder S, Xu J, Lee YK, Kang BG, Lee Y, Zhang J, Pletnikova O, Troncoso JC, Pirooznia S, Andrabi SA, Dawson VL, Dawson TM. Adult Conditional Knockout of PGC-1α Leads to Loss of Dopamine Neurons. Eneuro. 3. PMID 27622213 DOI: 10.1523/ENEURO.0183-16.2016 |
0.829 |
|
| 2016 |
Davis MY, Johnson CO, Leverenz JB, Weintraub D, Trojanowski JQ, Chen-Plotkin A, Van Deerlin VM, Quinn JF, Chung KA, Peterson-Hiller AL, Rosenthal LS, Dawson TM, Albert MS, Goldman JG, Stebbins GT, et al. Association of GBA Mutations and the E326K Polymorphism With Motor and Cognitive Progression in Parkinson Disease. Jama Neurology. PMID 27571329 DOI: 10.1001/Jamaneurol.2016.2245 |
0.37 |
|
| 2016 |
Zhang J, Li X, Kwansa H, Kim YT, Yi L, Hong G, Andrabi SA, Dawson VL, Dawson TM, Koehler RC, Yang ZJ. Augmentation of poly(ADP-ribose) polymerase-dependent neuronal cell death by acidosis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 27381826 DOI: 10.1177/0271678X16658491 |
0.523 |
|
| 2016 |
Brahmachari S, Ge P, Lee SH, Kim D, Karuppagounder SS, Kumar M, Mao X, Lee Y, Pletnikova O, Troncoso JC, Dawson VL, Dawson TM, Ko HS. Activation of tyrosine kinase c-Abl contributes to α-synuclein-induced neurodegeneration. The Journal of Clinical Investigation. PMID 27348587 DOI: 10.1172/Jci85456 |
0.806 |
|
| 2016 |
Nucifora FC, Nucifora LG, Ng CH, Arbez N, Guo Y, Roby E, Shani V, Engelender S, Wei D, Wang XF, Li T, Moore DJ, Pletnikova O, Troncoso JC, Sawa A, ... Dawson TM, et al. Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1. Nature Communications. 7: 11792. PMID 27273569 DOI: 10.1038/Ncomms11792 |
0.773 |
|
| 2016 |
Xu JC, Fan J, Wang X, Eacker SM, Kam TI, Chen L, Yin X, Zhu J, Chi Z, Jiang H, Chen R, Dawson TM, Dawson VL. Cultured networks of excitatory projection neurons and inhibitory interneurons for studying human cortical neurotoxicity. Science Translational Medicine. 8: 333ra48. PMID 27053772 DOI: 10.1126/Scitranslmed.Aad0623 |
0.805 |
|
| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin J, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Dawson TM, et al. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 Autophagy. 12: 443-443. PMID 26902590 DOI: 10.1080/15548627.2016.1147886 |
0.761 |
|
| 2016 |
Martin I, Kim JW, Dawson VL, Dawson TM. LRRK2 pathobiology in Parkinson's disease - virtual inclusion. Journal of Neurochemistry. PMID 26899799 DOI: 10.1111/Jnc.13549 |
0.66 |
|
| 2016 |
Karuppagounder SS, Xiong Y, Lee Y, Lawless MC, Kim D, Nordquist E, Martin I, Ge P, Brahmachari S, Jhaldiyal A, Kumar M, Andrabi SA, Dawson TM, Dawson VL. LRRK2 G2019S Transgenic Mice Display Increased Susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-Mediated Neurotoxicity. Journal of Chemical Neuroanatomy. PMID 26808467 DOI: 10.1016/J.Jchemneu.2016.01.007 |
0.81 |
|
| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Dawson TM, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356 |
0.779 |
|
| 2016 |
Philippens IHCHM, Franke SK, Kesteren REv, Hofman S, Wubben JAM, Smit AB, Moldovan A, Südmeyer M, Hammesfahr S, Antke C, Mamlins E, Beu M, Wojtecki L, Ferrea S, Schnitzler A, ... ... Dawson TM, et al. Contents Vol. 16, 2016 Neurodegenerative Diseases. 16. DOI: 10.1159/000448958 |
0.536 |
|
| 2016 |
Wang Y, An R, Umanah GK, Park H, Nambiar K, Eacker SM, Kim B, Bao L, Harraz MM, Chang C, Chen R, Wang JE, Kam TI, Jeong JS, Xie Z, ... ... Dawson TM, et al. A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1 Science. 354. DOI: 10.1126/science.aad6872 |
0.799 |
|
| 2016 |
Kutten KS, Eacker SM, Dawson VL, Dawson TM, Ratnanather T, Miller MI. An image registration pipeline for analysis of transsynaptic tracing in mice Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9788. DOI: 10.1117/12.2216233 |
0.796 |
|
| 2015 |
Choi S, Kim D, Kam TI, Yun S, Kim S, Park H, Hwang H, Pletnikova O, Troncoso JC, Dawson VL, Dawson TM, Ko HS. Lysosomal Enzyme Glucocerebrosidase Protects against Aβ1-42 Oligomer-Induced Neurotoxicity. Plos One. 10: e0143854. PMID 26629917 DOI: 10.1371/Journal.Pone.0143854 |
0.567 |
|
| 2015 |
Lee Y, Karuppagounder SS, Shin JH, Lee YI, Ko HS, Swing D, Jiang H, Kang SU, Lee BD, Kang HC, Kim D, Tessarollo L, Dawson VL, Dawson TM. Corrigendum: Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss. Nature Neuroscience. 18: 1861. PMID 26605883 DOI: 10.1038/Nn1215-1861A |
0.805 |
|
| 2015 |
Nam JH, Park ES, Won SY, Lee YA, Kim KI, Jeong JY, Baek JY, Cho EJ, Jin M, Chung YC, Lee BD, Kim SH, Kim EG, Byun K, Lee B, ... ... Dawson TM, et al. TRPV1 on astrocytes rescues nigral dopamine neurons in Parkinson's disease via CNTF. Brain : a Journal of Neurology. PMID 26490328 DOI: 10.1093/Brain/Awv297 |
0.601 |
|
| 2015 |
Rosenthal LS, Drake D, Alcalay RN, Babcock D, Bowman FD, Chen-Plotkin A, Dawson TM, Dewey RB, German DC, Huang X, Landin B, McAuliffe M, Petyuk VA, Scherzer CR, Hillaire-Clarke CS, et al. The NINDS Parkinson's disease biomarkers program. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 26442452 DOI: 10.1002/Mds.26438 |
0.367 |
|
| 2015 |
Stevens DA, Lee Y, Kang HC, Lee BD, Lee YI, Bower A, Jiang H, Kang SU, Andrabi SA, Dawson VL, Shin JH, Dawson TM. Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration. Proceedings of the National Academy of Sciences of the United States of America. 112: 11696-701. PMID 26324925 DOI: 10.1073/Pnas.1500624112 |
0.566 |
|
| 2015 |
Mata IF, Leverenz JB, Weintraub D, Trojanowski JQ, Chen-Plotkin A, Van Deerlin VM, Ritz B, Rausch R, Factor SA, Wood-Siverio C, Quinn JF, Chung KA, Peterson-Hiller AL, Goldman JG, Stebbins GT, ... ... Dawson TM, et al. GBA Variants are associated with a distinct pattern of cognitive deficits in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 26296077 DOI: 10.1002/Mds.26359 |
0.331 |
|
| 2015 |
Fiesel FC, Ando M, Hudec R, Hill AR, Castanedes-Casey M, Caulfield TR, Moussaud-Lamodière EL, Stankowski JN, Bauer PO, Lorenzo-Betancor O, Ferrer I, Arbelo JM, Siuda J, Chen L, Dawson VL, ... Dawson TM, et al. (Patho-)physiological relevance of PINK1-dependent ubiquitin phosphorylation. Embo Reports. PMID 26162776 DOI: 10.15252/Embr.201540514 |
0.594 |
|
| 2015 |
Beecham GW, Dickson DW, Scott WK, Martin ER, Schellenberg G, Nuytemans K, Larson EB, Buxbaum JD, Trojanowski JQ, Van Deerlin VM, Hurtig HI, Mash DC, Beach TG, Troncoso JC, Pletnikova O, ... ... Dawson TM, et al. PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease. Neurology. 84: 972-80. PMID 25663231 DOI: 10.1212/Wnl.0000000000001332 |
0.383 |
|
| 2015 |
Srivatsal S, Cholerton B, Leverenz JB, Wszolek ZK, Uitti RJ, Dickson DW, Weintraub D, Trojanowski JQ, Van Deerlin VM, Quinn JF, Chung KA, Peterson AL, Factor SA, Wood-Siverio C, Goldman JG, ... ... Dawson TM, et al. Cognitive profile of LRRK2-related Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 30: 728-33. PMID 25650144 DOI: 10.1002/Mds.26161 |
0.371 |
|
| 2015 |
Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, ... ... Dawson TM, et al. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death and Differentiation. 22: 58-73. PMID 25236395 DOI: 10.1038/Cdd.2014.137 |
0.506 |
|
| 2014 |
Martin I, Abalde-Atristain L, Kim JW, Dawson TM, Dawson VL. Abberant protein synthesis in G2019S LRRK2 Drosophila Parkinson disease-related phenotypes. Fly. 8: 165-9. PMID 25483009 DOI: 10.4161/19336934.2014.983382 |
0.824 |
|
| 2014 |
Harraz MM, Xu JC, Guiberson N, Dawson TM, Dawson VL. MiR-223 regulates the differentiation of immature neurons. Molecular and Cellular Therapies. 2. PMID 25400937 |
0.758 |
|
| 2014 |
Kageyama Y, Hoshijima M, Seo K, Bedja D, Sysa-Shah P, Andrabi SA, Chen W, Höke A, Dawson VL, Dawson TM, Gabrielson K, Kass DA, Iijima M, Sesaki H. Parkin-independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain. The Embo Journal. 33: 2798-813. PMID 25349190 DOI: 10.15252/Embj.201488658 |
0.516 |
|
| 2014 |
Prendergast J, Umanah GK, Yoo SW, Lagerlöf O, Motari MG, Cole RN, Huganir RL, Dawson TM, Dawson VL, Schnaar RL. Ganglioside regulation of AMPA receptor trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 13246-58. PMID 25253868 DOI: 10.1523/Jneurosci.1149-14.2014 |
0.544 |
|
| 2014 |
Martin I, Kim JW, Dawson VL, Dawson TM. LRRK2 pathobiology in Parkinson's disease. Journal of Neurochemistry. 131: 554-65. PMID 25251388 DOI: 10.1111/Jnc.12949 |
0.696 |
|
| 2014 |
Siuda J, Jasinska-Myga B, Boczarska-Jedynak M, Opala G, Fiesel FC, Moussaud-Lamodière EL, Scarffe LA, Dawson VL, Ross OA, Springer W, Dawson TM, Wszolek ZK. Early-onset Parkinson's disease due to PINK1 p.Q456X mutation--clinical and functional study. Parkinsonism & Related Disorders. 20: 1274-8. PMID 25226871 DOI: 10.1016/J.Parkreldis.2014.08.019 |
0.599 |
|
| 2014 |
Lu W, Karuppagounder SS, Springer DA, Allen MD, Zheng L, Chao B, Zhang Y, Dawson VL, Dawson TM, Lenardo M. Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson's-like movement disorder. Nature Communications. 5: 4930. PMID 25222142 DOI: 10.1038/Ncomms5930 |
0.813 |
|
| 2014 |
Tsika E, Kannan M, Foo CS, Dikeman D, Glauser L, Gellhaar S, Galter D, Knott GW, Dawson TM, Dawson VL, Moore DJ. Conditional expression of Parkinson's disease-related R1441C LRRK2 in midbrain dopaminergic neurons of mice causes nuclear abnormalities without neurodegeneration. Neurobiology of Disease. 71: 345-58. PMID 25174890 DOI: 10.1016/J.Nbd.2014.08.027 |
0.622 |
|
| 2014 |
Andrabi SA, Umanah GK, Chang C, Stevens DA, Karuppagounder SS, Gagné JP, Poirier GG, Dawson VL, Dawson TM. Poly(ADP-ribose) polymerase-dependent energy depletion occurs through inhibition of glycolysis. Proceedings of the National Academy of Sciences of the United States of America. 111: 10209-14. PMID 24987120 DOI: 10.1073/Pnas.1405158111 |
0.807 |
|
| 2014 |
Sagal J, Zhan X, Xu J, Tilghman J, Karuppagounder SS, Chen L, Dawson VL, Dawson TM, Laterra J, Ying M. Proneural transcription factor Atoh1 drives highly efficient differentiation of human pluripotent stem cells into dopaminergic neurons. Stem Cells Translational Medicine. 3: 888-98. PMID 24904172 DOI: 10.5966/Sctm.2013-0213 |
0.825 |
|
| 2014 |
Chen YC, Umanah GK, Dephoure N, Andrabi SA, Gygi SP, Dawson TM, Dawson VL, Rutter J. Msp1/ATAD1 maintains mitochondrial function by facilitating the degradation of mislocalized tail-anchored proteins. The Embo Journal. 33: 1548-64. PMID 24843043 DOI: 10.15252/Embj.201487943 |
0.501 |
|
| 2014 |
Karuppagounder SS, Brahmachari S, Lee Y, Dawson VL, Dawson TM, Ko HS. The c-Abl inhibitor, nilotinib, protects dopaminergic neurons in a preclinical animal model of Parkinson's disease. Scientific Reports. 4: 4874. PMID 24786396 DOI: 10.1038/Srep04874 |
0.833 |
|
| 2014 |
Chi Z, Byrne ST, Dolinko A, Harraz MM, Kim MS, Umanah G, Zhong J, Chen R, Zhang J, Xu J, Chen L, Pandey A, Dawson TM, Dawson VL. Botch is a γ-glutamyl cyclotransferase that deglycinates and antagonizes Notch. Cell Reports. 7: 681-8. PMID 24767995 DOI: 10.1016/J.Celrep.2014.03.048 |
0.786 |
|
| 2014 |
Scarffe LA, Stevens DA, Dawson VL, Dawson TM. Parkin and PINK1: much more than mitophagy. Trends in Neurosciences. 37: 315-24. PMID 24735649 DOI: 10.1016/J.Tins.2014.03.004 |
0.575 |
|
| 2014 |
Martin I, Kim JW, Lee BD, Kang HC, Xu JC, Jia H, Stankowski J, Kim MS, Zhong J, Kumar M, Andrabi SA, Xiong Y, Dickson DW, Wszolek ZK, Pandey A, ... Dawson TM, et al. Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease. Cell. 157: 472-85. PMID 24725412 DOI: 10.1016/J.Cell.2014.01.064 |
0.761 |
|
| 2014 |
Fatokun AA, Dawson VL, Dawson TM. Parthanatos: mitochondrial-linked mechanisms and therapeutic opportunities. British Journal of Pharmacology. 171: 2000-16. PMID 24684389 DOI: 10.1111/Bph.12416 |
0.543 |
|
| 2014 |
Beal MF, Oakes D, Shoulson I, Henchcliffe C, Galpern WR, Haas R, Juncos JL, Nutt JG, Voss TS, Ravina B, Shults CM, Helles K, Snively V, Lew MF, ... ... Dawson TM, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. Jama Neurology. 71: 543-52. PMID 24664227 DOI: 10.1001/Jamaneurol.2014.131 |
0.314 |
|
| 2014 |
Xiao J, Li Y, Prandovszky E, Karuppagounder SS, Talbot CC, Dawson VL, Dawson TM, Yolken RH. MicroRNA-132 dysregulation in Toxoplasma gondii infection has implications for dopamine signaling pathway. Neuroscience. 268: 128-38. PMID 24657774 DOI: 10.1016/J.Neuroscience.2014.03.015 |
0.782 |
|
| 2014 |
Pirooznia SK, Dawson VL, Dawson TM. Motor neuron death in ALS: programmed by astrocytes? Neuron. 81: 961-3. PMID 24607221 DOI: 10.1016/J.Neuron.2014.02.024 |
0.514 |
|
| 2014 |
Nuytemans K, Inchausti V, Beecham GW, Wang L, Dickson DW, Trojanowski JQ, Lee VM, Mash DC, Frosch MP, Foroud TM, Honig LS, Montine TJ, Dawson TM, Martin ER, Scott WK, et al. Absence of C9ORF72 expanded or intermediate repeats in autopsy-confirmed Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 827-30. PMID 24573903 DOI: 10.1002/Mds.25838 |
0.384 |
|
| 2014 |
Stafa K, Tsika E, Moser R, Musso A, Glauser L, Jones A, Biskup S, Xiong Y, Bandopadhyay R, Dawson VL, Dawson TM, Moore DJ. Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamily. Human Molecular Genetics. 23: 2055-77. PMID 24282027 DOI: 10.1093/Hmg/Ddt600 |
0.593 |
|
| 2014 |
Lee YI, Giovinazzo D, Kang HC, Lee Y, Jeong JS, Doulias PT, Xie Z, Hu J, Ghasemi M, Ischiropoulos H, Qian J, Zhu H, Blackshaw S, Dawson VL, Dawson TM. Protein microarray characterization of the S-nitrosoproteome. Molecular & Cellular Proteomics : McP. 13: 63-72. PMID 24105792 DOI: 10.1074/Mcp.M113.032235 |
0.778 |
|
| 2014 |
Dawson TM, Dawson VL. Parkin plays a role in sporadic Parkinson's disease. Neuro-Degenerative Diseases. 13: 69-71. PMID 24029689 DOI: 10.1159/000354307 |
0.576 |
|
| 2013 |
Migheli R, Del Giudice MG, Spissu Y, Sanna G, Xiong Y, Dawson TM, Dawson VL, Galioto M, Rocchitta G, Biosa A, Serra PA, Carri MT, Crosio C, Iaccarino C. LRRK2 affects vesicle trafficking, neurotransmitter extracellular level and membrane receptor localization. Plos One. 8: e77198. PMID 24167564 DOI: 10.1371/Journal.Pone.0077198 |
0.585 |
|
| 2013 |
Xu JC, Dawson VL, Dawson TM. Usp16: key controller of stem cells in Down syndrome. The Embo Journal. 32: 2788-9. PMID 24076652 DOI: 10.1038/Emboj.2013.220 |
0.569 |
|
| 2013 |
Brundin P, Barker RA, Conn PJ, Dawson TM, Kieburtz K, Lees AJ, Schwarzschild MA, Tanner CM, Isaacs T, Duffen J, Matthews H, Wyse RK. Linked clinical trials--the development of new clinical learning studies in Parkinson's disease using screening of multiple prospective new treatments. Journal of Parkinson's Disease. 3: 231-9. PMID 24018336 DOI: 10.3233/Jpd-139000 |
0.343 |
|
| 2013 |
Eacker SM, Dawson TM, Dawson VL. The interplay of microRNA and neuronal activity in health and disease. Frontiers in Cellular Neuroscience. 7: 136. PMID 23986658 DOI: 10.3389/Fncel.2013.00136 |
0.77 |
|
| 2013 |
Lee Y, Karuppagounder SS, Shin JH, Lee YI, Ko HS, Swing D, Jiang H, Kang SU, Lee BD, Kang HC, Kim D, Tessarollo L, Dawson VL, Dawson TM. Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss. Nature Neuroscience. 16: 1392-400. PMID 23974709 DOI: 10.1038/Nn.3500 |
0.839 |
|
| 2013 |
Fatokun AA, Liu JO, Dawson VL, Dawson TM. Identification through high-throughput screening of 4'-methoxyflavone and 3',4'-dimethoxyflavone as novel neuroprotective inhibitors of parthanatos. British Journal of Pharmacology. 169: 1263-78. PMID 23550801 DOI: 10.1111/Bph.12201 |
0.539 |
|
| 2013 |
Vandiver MS, Paul BD, Xu R, Karuppagounder S, Rao F, Snowman AM, Ko HS, Lee YI, Dawson VL, Dawson TM, Sen N, Snyder SH. Sulfhydration mediates neuroprotective actions of parkin. Nature Communications. 4: 1626. PMID 23535647 DOI: 10.1038/Ncomms2623 |
0.806 |
|
| 2013 |
Krietsch J, Rouleau M, Pic É, Ethier C, Dawson TM, Dawson VL, Masson JY, Poirier GG, Gagné JP. Reprogramming cellular events by poly(ADP-ribose)-binding proteins. Molecular Aspects of Medicine. 34: 1066-87. PMID 23268355 DOI: 10.1016/J.Mam.2012.12.005 |
0.495 |
|
| 2013 |
Calabresi P, Di Filippo M, Gallina A, Wang Y, Stankowski JN, Picconi B, Dawson VL, Dawson TM. New synaptic and molecular targets for neuroprotection in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 51-60. PMID 22927178 DOI: 10.1002/Mds.25096 |
0.607 |
|
| 2012 |
Ahmed I, Liang Y, Schools S, Dawson VL, Dawson TM, Savitt JM. Development and characterization of a new Parkinson's disease model resulting from impaired autophagy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16503-9. PMID 23152632 DOI: 10.1523/Jneurosci.0209-12.2012 |
0.617 |
|
| 2012 |
Harraz MM, Eacker SM, Wang X, Dawson TM, Dawson VL. MicroRNA-223 is neuroprotective by targeting glutamate receptors. Proceedings of the National Academy of Sciences of the United States of America. 109: 18962-7. PMID 23112146 DOI: 10.1073/Pnas.1121288109 |
0.792 |
|
| 2012 |
Xiong Y, Dawson VL, Dawson TM. LRRK2 GTPase dysfunction in the pathogenesis of Parkinson's disease. Biochemical Society Transactions. 40: 1074-9. PMID 22988868 DOI: 10.1042/Bst20120093 |
0.567 |
|
| 2012 |
Lee Y, Dawson VL, Dawson TM. Animal models of Parkinson's disease: vertebrate genetics. Cold Spring Harbor Perspectives in Medicine. 2. PMID 22960626 DOI: 10.1101/Cshperspect.A009324 |
0.565 |
|
| 2012 |
Wray S, Self M, Lewis PA, Taanman JW, Ryan NS, Mahoney CJ, Liang Y, Devine MJ, Sheerin UM, Houlden H, Morris HR, Healy D, ... ... Dawson TM, et al. Creation of an open-access, mutation-defined fibroblast resource for neurological disease research. Plos One. 7: e43099. PMID 22952635 DOI: 10.1371/Journal.Pone.0043099 |
0.322 |
|
| 2012 |
Cooper O, Seo H, Andrabi S, Guardia-Laguarta C, Graziotto J, Sundberg M, McLean JR, Carrillo-Reid L, Xie Z, Osborn T, Hargus G, Deleidi M, Lawson T, Bogetofte H, Perez-Torres E, ... ... Dawson TM, et al. Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease. Science Translational Medicine. 4: 141ra90. PMID 22764206 DOI: 10.1126/Scitranslmed.3003985 |
0.584 |
|
| 2012 |
Lee BD, Dawson VL, Dawson TM. Leucine-rich repeat kinase 2 (LRRK2) as a potential therapeutic target in Parkinson's disease. Trends in Pharmacological Sciences. 33: 365-73. PMID 22578536 DOI: 10.1016/J.Tips.2012.04.001 |
0.589 |
|
| 2012 |
Chi Z, Zhang J, Tokunaga A, Harraz MM, Byrne ST, Dolinko A, Xu J, Blackshaw S, Gaiano N, Dawson TM, Dawson VL. Botch promotes neurogenesis by antagonizing Notch. Developmental Cell. 22: 707-20. PMID 22445366 DOI: 10.1016/J.Devcel.2012.02.011 |
0.795 |
|
| 2012 |
Xiong Y, Yuan C, Chen R, Dawson TM, Dawson VL. ArfGAP1 is a GTPase activating protein for LRRK2: reciprocal regulation of ArfGAP1 by LRRK2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 3877-86. PMID 22423108 DOI: 10.1523/Jneurosci.4566-11.2012 |
0.556 |
|
| 2012 |
Daher JP, Pletnikova O, Biskup S, Musso A, Gellhaar S, Galter D, Troncoso JC, Lee MK, Dawson TM, Dawson VL, Moore DJ. Neurodegenerative phenotypes in an A53T α-synuclein transgenic mouse model are independent of LRRK2. Human Molecular Genetics. 21: 2420-31. PMID 22357653 DOI: 10.1093/Hmg/Dds057 |
0.609 |
|
| 2012 |
Stankowski JN, Dawson VL, Dawson TM. Ironing out tau's role in parkinsonism. Nature Medicine. 18: 197-8. PMID 22310680 DOI: 10.1038/Nm.2668 |
0.54 |
|
| 2012 |
Nikonova EV, Xiong Y, Tanis KQ, Dawson VL, Vogel RL, Finney EM, Stone DJ, Reynolds IJ, Kern JT, Dawson TM. Transcriptional responses to loss or gain of function of the leucine-rich repeat kinase 2 (LRRK2) gene uncover biological processes modulated by LRRK2 activity. Human Molecular Genetics. 21: 163-74. PMID 21972245 DOI: 10.1093/Hmg/Ddr451 |
0.696 |
|
| 2012 |
Lee BD, Li X, Dawson TM, Dawson VL. Measuring the activity of leucine-rich repeat kinase 2: a kinase involved in Parkinson's disease. Methods in Molecular Biology (Clifton, N.J.). 795: 45-54. PMID 21960214 DOI: 10.1007/978-1-61779-337-0_3 |
0.625 |
|
| 2012 |
Galluzzi L, Vitale I, Abrams JM, Alnemri ES, Baehrecke EH, Blagosklonny MV, Dawson TM, Dawson VL, El-Deiry WS, Fulda S, Gottlieb E, Green DR, Hengartner MO, Kepp O, Knight RA, et al. Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death and Differentiation. 19: 107-20. PMID 21760595 DOI: 10.1038/cdd.2011.96 |
0.415 |
|
| 2012 |
Thomas B, Mandir AS, West N, Liu Y, Andrabi SA, Stirling W, Dawson VL, Dawson TM, Lee MK. Correction: Resistance to MPTP-Neurotoxicity in α-Synuclein Knockout Mice Is Complemented by Human α-Synuclein and Associated with Increased β-Synuclein and Akt Activation Plos One. 7. DOI: 10.1371/annotation/f743434e-a6bf-4c6c-a836-ae5af66035a4 |
0.438 |
|
| 2011 |
Eacker SM, Keuss MJ, Berezikov E, Dawson VL, Dawson TM. Neuronal activity regulates hippocampal miRNA expression. Plos One. 6: e25068. PMID 21984899 DOI: 10.1371/Journal.Pone.0025068 |
0.76 |
|
| 2011 |
Kang HC, Lee YI, Shin JH, Andrabi SA, Chi Z, Gagné JP, Lee Y, Ko HS, Lee BD, Poirier GG, Dawson VL, Dawson TM. Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage. Proceedings of the National Academy of Sciences of the United States of America. 108: 14103-8. PMID 21825151 DOI: 10.1073/Pnas.1108799108 |
0.504 |
|
| 2011 |
Ramsden N, Perrin J, Ren Z, Lee BD, Zinn N, Dawson VL, Tam D, Bova M, Lang M, Drewes G, Bantscheff M, Bard F, Dawson TM, Hopf C. Chemoproteomics-based design of potent LRRK2-selective lead compounds that attenuate Parkinson's disease-related toxicity in human neurons. Acs Chemical Biology. 6: 1021-8. PMID 21812418 DOI: 10.1021/Cb2002413 |
0.575 |
|
| 2011 |
Chew KC, Ang ET, Tai YK, Tsang F, Lo SQ, Ong E, Ong WY, Shen HM, Lim KL, Dawson VL, Dawson TM, Soong TW. Enhanced autophagy from chronic toxicity of iron and mutant A53T α-synuclein: implications for neuronal cell death in Parkinson disease. The Journal of Biological Chemistry. 286: 33380-9. PMID 21795716 DOI: 10.1074/Jbc.M111.268409 |
0.727 |
|
| 2011 |
Liu Z, Hamamichi S, Lee BD, Yang D, Ray A, Caldwell GA, Caldwell KA, Dawson TM, Smith WW, Dawson VL. Inhibitors of LRRK2 kinase attenuate neurodegeneration and Parkinson-like phenotypes in Caenorhabditis elegans and Drosophila Parkinson's disease models. Human Molecular Genetics. 20: 3933-42. PMID 21768216 DOI: 10.1093/Hmg/Ddr312 |
0.596 |
|
| 2011 |
Dawson TM, Dawson VL. A lysosomal lair for a pathogenic protein pair. Science Translational Medicine. 3: 91ps28. PMID 21753118 DOI: 10.1126/Scitranslmed.3002808 |
0.584 |
|
| 2011 |
Martin I, Dawson VL, Dawson TM. Recent advances in the genetics of Parkinson's disease. Annual Review of Genomics and Human Genetics. 12: 301-25. PMID 21639795 DOI: 10.1146/Annurev-Genom-082410-101440 |
0.677 |
|
| 2011 |
Andrabi SA, Kang HC, Haince JF, Lee YI, Zhang J, Chi Z, West AB, Koehler RC, Poirier GG, Dawson TM, Dawson VL. Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly(ADP-ribose) polymer-induced cell death. Nature Medicine. 17: 692-9. PMID 21602803 DOI: 10.1038/Nm.2387 |
0.509 |
|
| 2011 |
Zhang J, Wang Y, Chi Z, Keuss MJ, Pai YM, Kang HC, Shin JH, Bugayenko A, Wang H, Xiong Y, Pletnikov MV, Mattson MP, Dawson TM, Dawson VL. The AAA+ ATPase Thorase regulates AMPA receptor-dependent synaptic plasticity and behavior. Cell. 145: 284-99. PMID 21496646 DOI: 10.1016/J.Cell.2011.03.016 |
0.56 |
|
| 2011 |
Ramonet D, Daher JP, Lin BM, Stafa K, Kim J, Banerjee R, Westerlund M, Pletnikova O, Glauser L, Yang L, Liu Y, Swing DA, Beal MF, Troncoso JC, McCaffery JM, ... ... Dawson TM, et al. Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2. Plos One. 6: e18568. PMID 21494637 DOI: 10.1371/Journal.Pone.0018568 |
0.612 |
|
| 2011 |
Wang Y, Kim NS, Haince JF, Kang HC, David KK, Andrabi SA, Poirier GG, Dawson VL, Dawson TM. Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos). Science Signaling. 4: ra20. PMID 21467298 DOI: 10.1126/Scisignal.2000902 |
0.525 |
|
| 2011 |
Shin JH, Ko HS, Kang H, Lee Y, Lee YI, Pletinkova O, Troconso JC, Dawson VL, Dawson TM. PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease. Cell. 144: 689-702. PMID 21376232 DOI: 10.1016/J.Cell.2011.02.010 |
0.625 |
|
| 2011 |
Thomas B, Mandir AS, West N, Liu Y, Andrabi SA, Stirling W, Dawson VL, Dawson TM, Lee MK. Resistance to MPTP-neurotoxicity in α-synuclein knockout mice is complemented by human α-synuclein and associated with increased β-synuclein and Akt activation. Plos One. 6: e16706. PMID 21304957 DOI: 10.1371/Journal.Pone.0016706 |
0.601 |
|
| 2011 |
Harraz MM, Dawson TM, Dawson VL. MicroRNAs in Parkinson's disease. Journal of Chemical Neuroanatomy. 42: 127-30. PMID 21295133 DOI: 10.1016/J.Jchemneu.2011.01.005 |
0.765 |
|
| 2011 |
Dawson VL, Dawson TM. Intracellular Signaling: Mediators and Protective Responses Stroke. 154-161. DOI: 10.1016/B978-1-4160-5478-8.10010-7 |
0.38 |
|
| 2011 |
Xu J, Dawson TM. A perfect “Match” for in vitro human disease modeling and autologous cell-based transplantation therapy: Generating genetically identical Parkinson's disease and control pluripotent stem cells by precise gene targeting Movement Disorders. 26: 1804-1804. DOI: 10.1002/Mds.23924 |
0.31 |
|
| 2010 |
Dai C, Liang D, Li H, Sasaki M, Dawson TM, Dawson VL. Functional identification of neuroprotective molecules. Plos One. 5: e15008. PMID 21124846 DOI: 10.1371/Journal.Pone.0015008 |
0.531 |
|
| 2010 |
Ko HS, Lee Y, Shin JH, Karuppagounder SS, Gadad BS, Koleske AJ, Pletnikova O, Troncoso JC, Dawson VL, Dawson TM. Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function. Proceedings of the National Academy of Sciences of the United States of America. 107: 16691-6. PMID 20823226 DOI: 10.1073/Pnas.1006083107 |
0.819 |
|
| 2010 |
Lee BD, Shin JH, VanKampen J, Petrucelli L, West AB, Ko HS, Lee YI, Maguire-Zeiss KA, Bowers WJ, Federoff HJ, Dawson VL, Dawson TM. Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease. Nature Medicine. 16: 998-1000. PMID 20729864 DOI: 10.1038/Nm.2199 |
0.559 |
|
| 2010 |
Martin I, Dawson VL, Dawson TM. The impact of genetic research on our understanding of Parkinson's disease. Progress in Brain Research. 183: 21-41. PMID 20696313 DOI: 10.1016/S0079-6123(10)83002-X |
0.678 |
|
| 2010 |
Li X, Moore DJ, Xiong Y, Dawson TM, Dawson VL. Reevaluation of phosphorylation sites in the Parkinson disease-associated leucine-rich repeat kinase 2. The Journal of Biological Chemistry. 285: 29569-76. PMID 20595391 DOI: 10.1074/Jbc.M110.127639 |
0.623 |
|
| 2010 |
Dawson TM, Ko HS, Dawson VL. Genetic animal models of Parkinson's disease. Neuron. 66: 646-61. PMID 20547124 DOI: 10.1016/J.Neuron.2010.04.034 |
0.579 |
|
| 2010 |
Zheng S, Eacker SM, Hong SJ, Gronostajski RM, Dawson TM, Dawson VL. NMDA-induced neuronal survival is mediated through nuclear factor I-A in mice. The Journal of Clinical Investigation. 120: 2446-56. PMID 20516644 DOI: 10.1172/Jci33144 |
0.806 |
|
| 2010 |
Xu Z, Zhang J, David KK, Yang ZJ, Li X, Dawson TM, Dawson VL, Koehler RC. Endonuclease G does not play an obligatory role in poly(ADP-ribose) polymerase-dependent cell death after transient focal cerebral ischemia. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 299: R215-21. PMID 20427721 DOI: 10.1152/Ajpregu.00747.2009 |
0.49 |
|
| 2010 |
Xiong Y, Coombes CE, Kilaru A, Li X, Gitler AD, Bowers WJ, Dawson VL, Dawson TM, Moore DJ. GTPase activity plays a key role in the pathobiology of LRRK2. Plos Genetics. 6: e1000902. PMID 20386743 DOI: 10.1371/Journal.Pgen.1000902 |
0.683 |
|
| 2010 |
Li X, Klaus JA, Zhang J, Xu Z, Kibler KK, Andrabi SA, Rao K, Yang ZJ, Dawson TM, Dawson VL, Koehler RC. Contributions of poly(ADP-ribose) polymerase-1 and -2 to nuclear translocation of apoptosis-inducing factor and injury from focal cerebral ischemia. Journal of Neurochemistry. 113: 1012-22. PMID 20236222 DOI: 10.1111/J.1471-4159.2010.06667.X |
0.517 |
|
| 2010 |
Dawson TM, Dawson VL. The role of parkin in familial and sporadic Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 25: S32-9. PMID 20187240 DOI: 10.1002/Mds.22798 |
0.583 |
|
| 2010 |
Smith WW, Liu Z, Liang Y, Masuda N, Swing DA, Jenkins NA, Copeland NG, Troncoso JC, Pletnikov M, Dawson TM, Martin LJ, Moran TH, Lee MK, Borchelt DR, Ross CA. Synphilin-1 attenuates neuronal degeneration in the A53T alpha-synuclein transgenic mouse model. Human Molecular Genetics. 19: 2087-98. PMID 20185556 DOI: 10.1093/Hmg/Ddq086 |
0.547 |
|
| 2010 |
Vives-Bauza C, Zhou C, Huang Y, Cui M, de Vries RL, Kim J, May J, Tocilescu MA, Liu W, Ko HS, Magrané J, Moore DJ, Dawson VL, Grailhe R, Dawson TM, et al. PINK1-dependent recruitment of Parkin to mitochondria in mitophagy. Proceedings of the National Academy of Sciences of the United States of America. 107: 378-83. PMID 19966284 DOI: 10.1073/Pnas.0911187107 |
0.528 |
|
| 2010 |
Lee YI, Dawson TM, Dawson VL. Role of no in neurodegeneration Encyclopedia of Neuroscience. 415-420. DOI: 10.1016/B978-008045046-9.00526-X |
0.406 |
|
| 2010 |
Kang HC, Dawson TM, Dawson VL. Excitotoxic programmed cell death involves caspase-independent mechanisms Acute Neuronal Injury: the Role of Excitotoxic Programmed Cell Death Mechanisms. 79-88. DOI: 10.1007/978-0-387-73226-8_5 |
0.396 |
|
| 2009 |
Andres-Mateos E, Mejias R, Sasaki M, Li X, Lin BM, Biskup S, Zhang L, Banerjee R, Thomas B, Yang L, Liu G, Beal MF, Huso DL, Dawson TM, Dawson VL. Unexpected lack of hypersensitivity in LRRK2 knock-out mice to MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine). The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 15846-50. PMID 20016100 DOI: 10.1523/Jneurosci.4357-09.2009 |
0.684 |
|
| 2009 |
Eacker SM, Dawson TM, Dawson VL. Understanding microRNAs in neurodegeneration. Nature Reviews. Neuroscience. 10: 837-41. PMID 19904280 DOI: 10.1038/Nrn2726 |
0.763 |
|
| 2009 |
Yu SW, Wang Y, Frydenlund DS, Ottersen OP, Dawson VL, Dawson TM. Outer mitochondrial membrane localization of apoptosis-inducing factor: mechanistic implications for release. Asn Neuro. 1. PMID 19863494 DOI: 10.1042/An20090046 |
0.517 |
|
| 2009 |
Shin JH, Dawson VL, Dawson TM. SnapShot: pathogenesis of Parkinson's disease. Cell. 139: 440.e1-2. PMID 19837042 DOI: 10.1016/J.Cell.2009.09.026 |
0.587 |
|
| 2009 |
Ng CH, Mok SZ, Koh C, Ouyang X, Fivaz ML, Tan EK, Dawson VL, Dawson TM, Yu F, Lim KL. Parkin protects against LRRK2 G2019S mutant-induced dopaminergic neurodegeneration in Drosophila. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 11257-62. PMID 19741132 DOI: 10.1523/Jneurosci.2375-09.2009 |
0.723 |
|
| 2009 |
Higashi S, Moore DJ, Yamamoto R, Minegishi M, Sato K, Togo T, Katsuse O, Uchikado H, Furukawa Y, Hino H, Kosaka K, Emson PC, Wada K, Dawson VL, Dawson TM, et al. Abnormal localization of leucine-rich repeat kinase 2 to the endosomal-lysosomal compartment in lewy body disease. Journal of Neuropathology and Experimental Neurology. 68: 994-1005. PMID 19680143 DOI: 10.1097/Nen.0B013E3181B44Ed8 |
0.517 |
|
| 2009 |
Daher JP, Ying M, Banerjee R, McDonald RS, Hahn MD, Yang L, Flint Beal M, Thomas B, Dawson VL, Dawson TM, Moore DJ. Conditional transgenic mice expressing C-terminally truncated human alpha-synuclein (alphaSyn119) exhibit reduced striatal dopamine without loss of nigrostriatal pathway dopaminergic neurons. Molecular Neurodegeneration. 4: 34. PMID 19630976 DOI: 10.1186/1750-1326-4-34 |
0.589 |
|
| 2009 |
Hoang T, Choi DK, Nagai M, Wu DC, Nagata T, Prou D, Wilson GL, Vila M, Jackson-Lewis V, Dawson VL, Dawson TM, Chesselet MF, Przedborski S. Neuronal NOS and cyclooxygenase-2 contribute to DNA damage in a mouse model of Parkinson disease. Free Radical Biology & Medicine. 47: 1049-56. PMID 19616617 DOI: 10.1016/J.Freeradbiomed.2009.07.013 |
0.569 |
|
| 2009 |
Waxman EA, Covy JP, Bukh I, Li X, Dawson TM, Giasson BI. Leucine-rich repeat kinase 2 expression leads to aggresome formation that is not associated with alpha-synuclein inclusions. Journal of Neuropathology and Experimental Neurology. 68: 785-96. PMID 19535993 DOI: 10.1097/Nen.0B013E3181Aaf4Fd |
0.466 |
|
| 2009 |
Wang Y, Kim NS, Li X, Greer PA, Koehler RC, Dawson VL, Dawson TM. Calpain activation is not required for AIF translocation in PARP-1-dependent cell death (parthanatos). Journal of Neurochemistry. 110: 687-96. PMID 19457082 DOI: 10.1111/J.1471-4159.2009.06167.X |
0.515 |
|
| 2009 |
Wang Y, Dawson VL, Dawson TM. Poly(ADP-ribose) signals to mitochondrial AIF: a key event in parthanatos. Experimental Neurology. 218: 193-202. PMID 19332058 DOI: 10.1016/J.Expneurol.2009.03.020 |
0.509 |
|
| 2009 |
Tsang AH, Lee YI, Ko HS, Savitt JM, Pletnikova O, Troncoso JC, Dawson VL, Dawson TM, Chung KK. S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 106: 4900-5. PMID 19273858 DOI: 10.1073/Pnas.0810595106 |
0.608 |
|
| 2009 |
David KK, Andrabi SA, Dawson TM, Dawson VL. Parthanatos, a messenger of death. Frontiers in Bioscience (Landmark Edition). 14: 1116-28. PMID 19273119 DOI: 10.2741/3297 |
0.516 |
|
| 2009 |
Ko HS, Bailey R, Smith WW, Liu Z, Shin JH, Lee YI, Zhang YJ, Jiang H, Ross CA, Moore DJ, Patterson C, Petrucelli L, Dawson TM, Dawson VL. CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity. Proceedings of the National Academy of Sciences of the United States of America. 106: 2897-902. PMID 19196961 DOI: 10.1073/Pnas.0810123106 |
0.665 |
|
| 2009 |
Tsang AHK, Lee YI, Han SK, Savitt JM, Pletnikova O, Troncoso JC, Dawson VL, Dawson TM, Chung KKK. S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease (Proceedings of the National Academy of Sciences of the United States of America (2009) 106, 12, (4900-4905) DOI: 10.1073/pnas.0810595106) Proceedings of the National Academy of Sciences of the United States of America. 106: 8791. DOI: 10.1073/Pnas.0903257106 |
0.541 |
|
| 2008 |
Gupta A, Dawson VL, Dawson TM. What causes cell death in Parkinson's disease? Annals of Neurology. 64: S3-15. PMID 19127586 DOI: 10.1002/Ana.21573 |
0.569 |
|
| 2008 |
Andrabi SA, Dawson TM, Dawson VL. Mitochondrial and nuclear cross talk in cell death: parthanatos. Annals of the New York Academy of Sciences. 1147: 233-41. PMID 19076445 DOI: 10.1196/Annals.1427.014 |
0.535 |
|
| 2008 |
Gagné JP, Isabelle M, Lo KS, Bourassa S, Hendzel MJ, Dawson VL, Dawson TM, Poirier GG. Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes. Nucleic Acids Research. 36: 6959-76. PMID 18981049 DOI: 10.1093/Nar/Gkn771 |
0.494 |
|
| 2008 |
Moore DJ, Dawson TM. Value of genetic models in understanding the cause and mechanisms of Parkinson's disease. Current Neurology and Neuroscience Reports. 8: 288-96. PMID 18590612 DOI: 10.1007/S11910-008-0045-7 |
0.436 |
|
| 2008 |
Sen N, Hara MR, Kornberg MD, Cascio MB, Bae BI, Shahani N, Thomas B, Dawson TM, Dawson VL, Snyder SH, Sawa A. Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis. Nature Cell Biology. 10: 866-73. PMID 18552833 DOI: 10.1038/Ncb1747 |
0.8 |
|
| 2008 |
Wong ES, Tan JM, Soong WE, Hussein K, Nukina N, Dawson VL, Dawson TM, Cuervo AM, Lim KL. Autophagy-mediated clearance of aggresomes is not a universal phenomenon. Human Molecular Genetics. 17: 2570-82. PMID 18502787 DOI: 10.1093/Hmg/Ddn157 |
0.684 |
|
| 2008 |
Dawson TM. Non-autonomous cell death in Parkinson's disease. The Lancet. Neurology. 7: 474-5. PMID 18485311 DOI: 10.1016/S1474-4422(08)70099-1 |
0.437 |
|
| 2008 |
Wang L, Xie C, Greggio E, Parisiadou L, Shim H, Sun L, Chandran J, Lin X, Lai C, Yang WJ, Moore DJ, Dawson TM, Dawson VL, Chiosis G, Cookson MR, et al. The chaperone activity of heat shock protein 90 is critical for maintaining the stability of leucine-rich repeat kinase 2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 3384-91. PMID 18367605 DOI: 10.1523/Jneurosci.0185-08.2008 |
0.579 |
|
| 2008 |
Habib SL, Michel D, Masliah E, Thomas B, Ko HS, Dawson TM, Abboud H, Clark RA, Imam SZ. Role of tuberin in neuronal degeneration. Neurochemical Research. 33: 1113-6. PMID 18320306 DOI: 10.1007/S11064-007-9558-8 |
0.451 |
|
| 2008 |
Rudow G, O'Brien R, Savonenko AV, Resnick SM, Zonderman AB, Pletnikova O, Marsh L, Dawson TM, Crain BJ, West MJ, Troncoso JC. Morphometry of the human substantia nigra in ageing and Parkinson's disease. Acta Neuropathologica. 115: 461-70. PMID 18297291 DOI: 10.1007/S00401-008-0352-8 |
0.394 |
|
| 2008 |
Moore DJ, West AB, Dikeman DA, Dawson VL, Dawson TM. Parkin mediates the degradation-independent ubiquitination of Hsp70. Journal of Neurochemistry. 105: 1806-19. PMID 18248624 DOI: 10.1111/J.1471-4159.2008.05261.X |
0.541 |
|
| 2008 |
Harraz MM, Dawson TM, Dawson VL. Advances in neuronal cell death 2007. Stroke; a Journal of Cerebral Circulation. 39: 286-8. PMID 18187674 DOI: 10.1161/Strokeaha.107.511857 |
0.75 |
|
| 2008 |
Tan JM, Wong ES, Kirkpatrick DS, Pletnikova O, Ko HS, Tay SP, Ho MW, Troncoso J, Gygi SP, Lee MK, Dawson VL, Dawson TM, Lim KL. Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases. Human Molecular Genetics. 17: 431-9. PMID 17981811 DOI: 10.1093/Hmg/Ddm320 |
0.689 |
|
| 2008 |
Tan JMM, Wong ESP, Dawson VL, Dawson TM, Lim KL. Lysine 63-linked polyubiquitin potentially partners with p62 to promote the clearance of protein inclusions by autophagy Autophagy. 4: 251-253. DOI: 10.4161/Auto.5444 |
0.674 |
|
| 2008 |
Ying M, Dawson VL, Dawson TM. Genetic Models of Familial Parkinson's Disease Parkinson's Disease. 225-236. DOI: 10.1016/B978-0-12-374028-1.00017-8 |
0.442 |
|
| 2007 |
Dawson TM. Unraveling the role of defective genes in Parkinson's disease. Parkinsonism & Related Disorders. 13: S248-9. PMID 18267244 DOI: 10.1016/S1353-8020(08)70010-5 |
0.407 |
|
| 2007 |
Biskup S, Moore DJ, Rea A, Lorenz-Deperieux B, Coombes CE, Dawson VL, Dawson TM, West AB. Dynamic and redundant regulation of LRRK2 and LRRK1 expression. Bmc Neuroscience. 8: 102. PMID 18045479 DOI: 10.1186/1471-2202-8-102 |
0.509 |
|
| 2007 |
Cookson MR, Dauer W, Dawson T, Fon EA, Guo M, Shen J. The roles of kinases in familial Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11865-8. PMID 17978026 DOI: 10.1523/Jneurosci.3695-07.2007 |
0.436 |
|
| 2007 |
Andres-Mateos E, Perier C, Zhang L, Blanchard-Fillion B, Greco TM, Thomas B, Ko HS, Sasaki M, Ischiropoulos H, Przedborski S, Dawson TM, Dawson VL. DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase. Proceedings of the National Academy of Sciences of the United States of America. 104: 14807-12. PMID 17766438 DOI: 10.1073/Pnas.0703219104 |
0.55 |
|
| 2007 |
Poitras MF, Koh DW, Yu SW, Andrabi SA, Mandir AS, Poirier GG, Dawson VL, Dawson TM. Spatial and functional relationship between poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in the brain. Neuroscience. 148: 198-211. PMID 17640816 DOI: 10.1016/J.Neuroscience.2007.04.062 |
0.524 |
|
| 2007 |
Luo W, Wickramasinghe SR, Savitt JM, Griffin JW, Dawson TM, Ginty DD. A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons. Neuron. 54: 739-54. PMID 17553423 DOI: 10.1016/J.Neuron.2007.04.027 |
0.34 |
|
| 2007 |
Higashi S, Biskup S, West AB, Trinkaus D, Dawson VL, Faull RL, Waldvogel HJ, Arai H, Dawson TM, Moore DJ, Emson PC. Localization of Parkinson's disease-associated LRRK2 in normal and pathological human brain. Brain Research. 1155: 208-19. PMID 17512502 DOI: 10.1016/J.Brainres.2007.04.034 |
0.604 |
|
| 2007 |
Haince JF, Kozlov S, Dawson VL, Dawson TM, Hendzel MJ, Lavin MF, Poirier GG. Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents. The Journal of Biological Chemistry. 282: 16441-53. PMID 17428792 DOI: 10.1074/Jbc.M608406200 |
0.486 |
|
| 2007 |
Thomas B, von Coelln R, Mandir AS, Trinkaus DB, Farah MH, Leong Lim K, Calingasan NY, Flint Beal M, Dawson VL, Dawson TM. MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity. Neurobiology of Disease. 26: 312-22. PMID 17336077 DOI: 10.1016/J.Nbd.2006.12.021 |
0.602 |
|
| 2007 |
Wong ES, Tan JM, Wang C, Zhang Z, Tay SP, Zaiden N, Ko HS, Dawson VL, Dawson TM, Lim KL. Relative sensitivity of parkin and other cysteine-containing enzymes to stress-induced solubility alterations. The Journal of Biological Chemistry. 282: 12310-8. PMID 17329252 DOI: 10.1074/Jbc.M609466200 |
0.697 |
|
| 2007 |
Gupta A, Dawson TM. The role of stem cells in Parkinson's disease. Neurosurgery Clinics of North America. 18: 129-42, x-xi. PMID 17244560 DOI: 10.1016/J.Nec.2006.10.015 |
0.371 |
|
| 2007 |
West AB, Moore DJ, Choi C, Andrabi SA, Li X, Dikeman D, Biskup S, Zhang Z, Lim KL, Dawson VL, Dawson TM. Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity. Human Molecular Genetics. 16: 223-32. PMID 17200152 DOI: 10.1093/Hmg/Ddl471 |
0.743 |
|
| 2007 |
Higashi S, Moore DJ, Colebrooke RE, Biskup S, Dawson VL, Arai H, Dawson TM, Emson PC. Expression and localization of Parkinson's disease-associated leucine-rich repeat kinase 2 in the mouse brain. Journal of Neurochemistry. 100: 368-81. PMID 17101029 DOI: 10.1111/J.1471-4159.2006.04246.X |
0.609 |
|
| 2007 |
Li X, Nemoto M, Xu Z, Yu SW, Shimoji M, Andrabi SA, Haince JF, Poirier GG, Dawson TM, Dawson VL, Koehler RC. Influence of duration of focal cerebral ischemia and neuronal nitric oxide synthase on translocation of apoptosis-inducing factor to the nucleus. Neuroscience. 144: 56-65. PMID 17049179 DOI: 10.1016/J.Neuroscience.2006.08.065 |
0.515 |
|
| 2007 |
Jiang H, Wu YC, Nakamura M, Liang Y, Tanaka Y, Holmes S, Dawson VL, Dawson TM, Ross CA, Smith WW. Parkinson's disease genetic mutations increase cell susceptibility to stress: mutant alpha-synuclein enhances H2O2- and Sin-1-induced cell death. Neurobiology of Aging. 28: 1709-17. PMID 16978743 DOI: 10.1016/J.Neurobiolaging.2006.07.017 |
0.661 |
|
| 2007 |
Savitt JM, Dawson VL, Dawson TM. Parkinson Disease: Molecular Insights Molecular Neurology. 221-239. DOI: 10.1016/B978-012369509-3.50017-2 |
0.466 |
|
| 2007 |
Koh DW, Dawson TM, Dawson VL. Neurobiology of AIF and PARP in cerebral ischemia Handbook of Neurochemistry and Molecular Neurobiology: Acute Ischemic Injury and Repair in the Nervous System. 19-31. DOI: 10.1007/978-0-387-30383-3_2 |
0.359 |
|
| 2007 |
Sriram SR, Dawson VL, Dawson TM. Parkin and Neurodegeneration Protein Degradation. 4: 211-236. DOI: 10.1002/9783527619320.ch10c |
0.816 |
|
| 2006 |
Biskup S, Moore DJ, Celsi F, Higashi S, West AB, Andrabi SA, Kurkinen K, Yu SW, Savitt JM, Waldvogel HJ, Faull RL, Emson PC, Torp R, Ottersen OP, Dawson TM, et al. Localization of LRRK2 to membranous and vesicular structures in mammalian brain. Annals of Neurology. 60: 557-69. PMID 17120249 DOI: 10.1002/Ana.21019 |
0.523 |
|
| 2006 |
Andrabi SA, Kim NS, Yu SW, Wang H, Koh DW, Sasaki M, Klaus JA, Otsuka T, Zhang Z, Koehler RC, Hurn PD, Poirier GG, Dawson VL, Dawson TM. Poly(ADP-ribose) (PAR) polymer is a death signal. Proceedings of the National Academy of Sciences of the United States of America. 103: 18308-13. PMID 17116882 DOI: 10.1073/Pnas.0606526103 |
0.512 |
|
| 2006 |
Yu SW, Andrabi SA, Wang H, Kim NS, Poirier GG, Dawson TM, Dawson VL. Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death. Proceedings of the National Academy of Sciences of the United States of America. 103: 18314-9. PMID 17116881 DOI: 10.1073/Pnas.0606528103 |
0.487 |
|
| 2006 |
Dawson VL, Dawson TM. Mining for survival genes. Biochemical Society Transactions. 34: 1307-9. PMID 17073808 DOI: 10.1042/Bst0341307 |
0.499 |
|
| 2006 |
Dawson TM. Parkin and defective ubiquitination in Parkinson's disease. Journal of Neural Transmission. Supplementum. 209-13. PMID 17017531 DOI: 10.1007/978-3-211-45295-0_32 |
0.455 |
|
| 2006 |
Smith WW, Pei Z, Jiang H, Dawson VL, Dawson TM, Ross CA. Kinase activity of mutant LRRK2 mediates neuronal toxicity. Nature Neuroscience. 9: 1231-3. PMID 16980962 DOI: 10.1038/Nn1776 |
0.671 |
|
| 2006 |
Dawson TM, Dawson VL. Taming the clot-buster tPA. Nature Medicine. 12: 993-4. PMID 16960567 DOI: 10.1038/Nm0906-993 |
0.437 |
|
| 2006 |
Savitt JM, Dawson VL, Dawson TM. Diagnosis and treatment of Parkinson disease: molecules to medicine. The Journal of Clinical Investigation. 116: 1744-54. PMID 16823471 DOI: 10.1172/Jci29178 |
0.568 |
|
| 2006 |
Tan JM, Dawson TM. Parkin blushed by PINK1. Neuron. 50: 527-9. PMID 16701203 DOI: 10.1016/J.Neuron.2006.05.003 |
0.447 |
|
| 2006 |
Ko HS, Kim SW, Sriram SR, Dawson VL, Dawson TM. Identification of far upstream element-binding protein-1 as an authentic Parkin substrate. The Journal of Biological Chemistry. 281: 16193-6. PMID 16672220 DOI: 10.1074/Jbc.C600041200 |
0.797 |
|
| 2006 |
von Coelln R, Thomas B, Andrabi SA, Lim KL, Savitt JM, Saffary R, Stirling W, Bruno K, Hess EJ, Lee MK, Dawson VL, Dawson TM. Inclusion body formation and neurodegeneration are parkin independent in a mouse model of alpha-synucleinopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3685-96. PMID 16597723 DOI: 10.1523/Jneurosci.0414-06.2006 |
0.706 |
|
| 2006 |
Hara MR, Thomas B, Cascio MB, Bae BI, Hester LD, Dawson VL, Dawson TM, Sawa A, Snyder SH. Neuroprotection by pharmacologic blockade of the GAPDH death cascade. Proceedings of the National Academy of Sciences of the United States of America. 103: 3887-9. PMID 16505364 DOI: 10.1073/Pnas.0511321103 |
0.817 |
|
| 2006 |
Riccio A, Alvania RS, Lonze BE, Ramanan N, Kim T, Huang Y, Dawson TM, Snyder SH, Ginty DD. A nitric oxide signaling pathway controls CREB-mediated gene expression in neurons. Molecular Cell. 21: 283-94. PMID 16427017 DOI: 10.1016/J.Molcel.2005.12.006 |
0.563 |
|
| 2006 |
Moore DJ, Dawson VL, Dawson TM. Lessons from Drosophila models of DJ-1 deficiency. Science of Aging Knowledge Environment : Sage Ke. 2006: pe2. PMID 16407572 DOI: 10.1126/Sageke.2006.2.Pe2 |
0.609 |
|
| 2006 |
David KK, Sasaki M, Yu SW, Dawson TM, Dawson VL. EndoG is dispensable in embryogenesis and apoptosis. Cell Death and Differentiation. 13: 1147-55. PMID 16239930 DOI: 10.1038/sj.cdd.4401787 |
0.45 |
|
| 2006 |
Lim KL, Dawson VL, Dawson TM. Parkin-mediated lysine 63-linked polyubiquitination: a link to protein inclusions formation in Parkinson's and other conformational diseases? Neurobiology of Aging. 27: 524-9. PMID 16213628 DOI: 10.1016/J.Neurobiolaging.2005.07.023 |
0.728 |
|
| 2006 |
Zhang L, Dawson VL, Dawson TM. Role of nitric oxide in Parkinson's disease. Pharmacology & Therapeutics. 109: 33-41. PMID 16005074 DOI: 10.1016/J.Pharmthera.2005.05.007 |
0.588 |
|
| 2006 |
Ravichandran S, Dawson TM, Dawson VL. Ubiquitination by Parkin - Implications in Parkinson's disease The Proteasome in Neurodegeneration. 213-224. DOI: 10.1007/0-387-28500-8_13 |
0.492 |
|
| 2005 |
Smith WW, Pei Z, Jiang H, Moore DJ, Liang Y, West AB, Dawson VL, Dawson TM, Ross CA. Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration. Proceedings of the National Academy of Sciences of the United States of America. 102: 18676-81. PMID 16352719 DOI: 10.1073/Pnas.0508052102 |
0.692 |
|
| 2005 |
Hong SJ, Dawson VL, Dawson TM. Identification and evaluation of NO-regulated genes by differential analysis of primary cDNA library expression (DAzLE). Methods in Enzymology. 396: 359-68. PMID 16291245 DOI: 10.1016/S0076-6879(05)96030-8 |
0.69 |
|
| 2005 |
Chung KK, Dawson VL, Dawson TM. S-nitrosylation in Parkinson's disease and related neurodegenerative disorders. Methods in Enzymology. 396: 139-50. PMID 16291229 DOI: 10.1016/S0076-6879(05)96014-X |
0.575 |
|
| 2005 |
Wang C, Ko HS, Thomas B, Tsang F, Chew KC, Tay SP, Ho MW, Lim TM, Soong TW, Pletnikova O, Troncoso J, Dawson VL, Dawson TM, Lim KL. Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function. Human Molecular Genetics. 14: 3885-97. PMID 16278233 DOI: 10.1093/Hmg/Ddi413 |
0.739 |
|
| 2005 |
West AB, Moore DJ, Biskup S, Bugayenko A, Smith WW, Ross CA, Dawson VL, Dawson TM. Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity. Proceedings of the National Academy of Sciences of the United States of America. 102: 16842-7. PMID 16269541 DOI: 10.1073/Pnas.0507360102 |
0.663 |
|
| 2005 |
Smith WW, Jiang H, Pei Z, Tanaka Y, Morita H, Sawa A, Dawson VL, Dawson TM, Ross CA. Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity. Human Molecular Genetics. 14: 3801-11. PMID 16239241 DOI: 10.1093/Hmg/Ddi396 |
0.71 |
|
| 2005 |
Chung KK, Dawson TM, Dawson VL. Nitric oxide, S-nitrosylation and neurodegeneration. Cellular and Molecular Biology (Noisy-Le-Grand, France). 51: 247-54. PMID 16191392 |
0.455 |
|
| 2005 |
Ko HS, von Coelln R, Sriram SR, Kim SW, Chung KK, Pletnikova O, Troncoso J, Johnson B, Saffary R, Goh EL, Song H, Park BJ, Kim MJ, Kim S, Dawson VL, ... Dawson TM, et al. Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7968-78. PMID 16135753 DOI: 10.1523/Jneurosci.2172-05.2005 |
0.828 |
|
| 2005 |
Son JH, Kawamata H, Yoo MS, Kim DJ, Lee YK, Kim S, Dawson TM, Zhang H, Sulzer D, Yang L, Beal MF, Degiorgio LA, Chun HS, Baker H, Peng C. Neurotoxicity and behavioral deficits associated with Septin 5 accumulation in dopaminergic neurons. Journal of Neurochemistry. 94: 1040-53. PMID 16092945 DOI: 10.1111/J.1471-4159.2005.03257.X |
0.43 |
|
| 2005 |
Sriram SR, Li X, Ko HS, Chung KK, Wong E, Lim KL, Dawson VL, Dawson TM. Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin. Human Molecular Genetics. 14: 2571-86. PMID 16049031 DOI: 10.1093/Hmg/Ddi292 |
0.81 |
|
| 2005 |
Savitt JM, Jang SS, Mu W, Dawson VL, Dawson TM. Bcl-x is required for proper development of the mouse substantia nigra. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6721-8. PMID 16033881 DOI: 10.1523/Jneurosci.0760-05.2005 |
0.52 |
|
| 2005 |
Moore DJ, West AB, Dawson VL, Dawson TM. Molecular pathophysiology of Parkinson's disease. Annual Review of Neuroscience. 28: 57-87. PMID 16022590 DOI: 10.1146/Annurev.Neuro.28.061604.135718 |
0.613 |
|
| 2005 |
Smith WW, Margolis RL, Li X, Troncoso JC, Lee MK, Dawson VL, Dawson TM, Iwatsubo T, Ross CA. Alpha-synuclein phosphorylation enhances eosinophilic cytoplasmic inclusion formation in SH-SY5Y cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5544-52. PMID 15944382 DOI: 10.1523/Jneurosci.0482-05.2005 |
0.67 |
|
| 2005 |
Zhang L, Shimoji M, Thomas B, Moore DJ, Yu SW, Marupudi NI, Torp R, Torgner IA, Ottersen OP, Dawson TM, Dawson VL. Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis. Human Molecular Genetics. 14: 2063-73. PMID 15944198 DOI: 10.1093/Hmg/Ddi211 |
0.559 |
|
| 2005 |
Pletnikova O, West N, Lee MK, Rudow GL, Skolasky RL, Dawson TM, Marsh L, Troncoso JC. Abeta deposition is associated with enhanced cortical alpha-synuclein lesions in Lewy body diseases. Neurobiology of Aging. 26: 1183-92. PMID 15917102 DOI: 10.1016/J.Neurobiolaging.2004.10.006 |
0.318 |
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| 2005 |
West AB, Dawson VL, Dawson TM. To die or grow: Parkinson's disease and cancer. Trends in Neurosciences. 28: 348-52. PMID 15913799 DOI: 10.1016/J.Tins.2005.05.002 |
0.559 |
|
| 2005 |
Koh DW, Dawson TM, Dawson VL. Mediation of cell death by poly(ADP-ribose) polymerase-1. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 52: 5-14. PMID 15911329 DOI: 10.1016/J.Phrs.2005.02.011 |
0.544 |
|
| 2005 |
Berg D, Niwar M, Maass S, Zimprich A, Möller JC, Wuellner U, Schmitz-Hübsch T, Klein C, Tan EK, Schöls L, Marsh L, Dawson TM, Janetzky B, Müller T, Woitalla D, et al. Alpha-synuclein and Parkinson's disease: implications from the screening of more than 1,900 patients. Movement Disorders : Official Journal of the Movement Disorder Society. 20: 1191-4. PMID 15895422 DOI: 10.1002/Mds.20504 |
0.343 |
|
| 2005 |
Koh DW, Dawson TM, Dawson VL. Poly(ADP-ribosyl)ation regulation of life and death in the nervous system. Cellular and Molecular Life Sciences : Cmls. 62: 760-8. PMID 15868401 DOI: 10.1007/S00018-004-4508-Y |
0.575 |
|
| 2005 |
Pol O, Sasaki M, Jiménez N, Dawson VL, Dawson TM, Puig MM. The involvement of nitric oxide in the enhanced expression of mu-opioid receptors during intestinal inflammation in mice. British Journal of Pharmacology. 145: 758-66. PMID 15852037 DOI: 10.1038/Sj.Bjp.0706227 |
0.473 |
|
| 2005 |
Wang C, Tan JM, Ho MW, Zaiden N, Wong SH, Chew CL, Eng PW, Lim TM, Dawson TM, Lim KL. Alterations in the solubility and intracellular localization of parkin by several familial Parkinson's disease-linked point mutations. Journal of Neurochemistry. 93: 422-31. PMID 15816865 DOI: 10.1111/J.1471-4159.2005.03023.X |
0.651 |
|
| 2005 |
Shimoji M, Zhang L, Mandir AS, Dawson VL, Dawson TM. Absence of inclusion body formation in the MPTP mouse model of Parkinson's disease. Brain Research. Molecular Brain Research. 134: 103-8. PMID 15790534 DOI: 10.1016/J.Molbrainres.2005.01.012 |
0.567 |
|
| 2005 |
Lim KL, Chew KC, Tan JM, Wang C, Chung KK, Zhang Y, Tanaka Y, Smith W, Engelender S, Ross CA, Dawson VL, Dawson TM. Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2002-9. PMID 15728840 DOI: 10.1523/Jneurosci.4474-04.2005 |
0.75 |
|
| 2005 |
Koh DW, Dawson VL, Dawson TM. The road to survival goes through PARG. Cell Cycle (Georgetown, Tex.). 4: 397-9. PMID 15725727 DOI: 10.4161/Cc.4.3.1559 |
0.51 |
|
| 2005 |
Moore DJ, Zhang L, Troncoso J, Lee MK, Hattori N, Mizuno Y, Dawson TM, Dawson VL. Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress. Human Molecular Genetics. 14: 71-84. PMID 15525661 DOI: 10.1093/Hmg/Ddi007 |
0.592 |
|
| 2005 |
Kim SW, Ko HS, Dawson VL, Dawson TM. Recent advances in our understanding of Parkinson's disease Drug Discovery Today: Disease Mechanisms. 2: 427-433. DOI: 10.1016/J.Ddmec.2005.11.015 |
0.589 |
|
| 2004 |
Chung KK, Dawson TM. Parkin and Hsp70 sacked by BAG5. Neuron. 44: 899-901. PMID 15603730 DOI: 10.1016/J.Neuron.2004.12.007 |
0.45 |
|
| 2004 |
Koh DW, Lawler AM, Poitras MF, Sasaki M, Wattler S, Nehls MC, Stöger T, Poirier GG, Dawson VL, Dawson TM. Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality. Proceedings of the National Academy of Sciences of the United States of America. 101: 17699-704. PMID 15591342 DOI: 10.1073/Pnas.0406182101 |
0.488 |
|
| 2004 |
Wang H, Yu SW, Koh DW, Lew J, Coombs C, Bowers W, Federoff HJ, Poirier GG, Dawson TM, Dawson VL. Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10963-73. PMID 15574746 DOI: 10.1523/Jneurosci.3461-04.2004 |
0.531 |
|
| 2004 |
von Coelln R, Dawson VL, Dawson TM. Parkin-associated Parkinson's disease. Cell and Tissue Research. 318: 175-84. PMID 15503153 DOI: 10.1007/S00441-004-0924-4 |
0.585 |
|
| 2004 |
Dawson VL, Dawson TM. Deadly conversations: nuclear-mitochondrial cross-talk. Journal of Bioenergetics and Biomembranes. 36: 287-94. PMID 15377859 DOI: 10.1023/B:Jobb.0000041755.22613.8D |
0.582 |
|
| 2004 |
Hagberg H, Wilson MA, Matsushita H, Zhu C, Lange M, Gustavsson M, Poitras MF, Dawson TM, Dawson VL, Northington F, Johnston MV. PARP-1 gene disruption in mice preferentially protects males from perinatal brain injury. Journal of Neurochemistry. 90: 1068-75. PMID 15312162 DOI: 10.1111/J.1471-4159.2004.02547.X |
0.5 |
|
| 2004 |
Marsh L, Williams JR, Rocco M, Grill S, Munro C, Dawson TM. Psychiatric comorbidities in patients with Parkinson disease and psychosis. Neurology. 63: 293-300. PMID 15277623 DOI: 10.1212/01.Wnl.0000129843.15756.A3 |
0.306 |
|
| 2004 |
Von Coelln R, Thomas B, Savitt JM, Lim KL, Sasaki M, Hess EJ, Dawson VL, Dawson TM. Loss of locus coeruleus neurons and reduced startle in parkin null mice. Proceedings of the National Academy of Sciences of the United States of America. 101: 10744-9. PMID 15249681 DOI: 10.1073/Pnas.0401297101 |
0.751 |
|
| 2004 |
Petrucelli L, Dawson TM. Mechanism of neurodegenerative disease: role of the ubiquitin proteasome system. Annals of Medicine. 36: 315-20. PMID 15224658 DOI: 10.1080/07853890410031948 |
0.445 |
|
| 2004 |
Hong SJ, Dawson TM, Dawson VL. Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling. Trends in Pharmacological Sciences. 25: 259-64. PMID 15120492 DOI: 10.1016/J.Tips.2004.03.005 |
0.703 |
|
| 2004 |
Samdani AF, Kuchner EB, Rhines L, Adamson DC, Lawson C, Tyler B, Brem H, Dawson VL, Dawson TM. Astroglia induce cytotoxic effects on brain tumors via a nitric oxide-dependent pathway both in vitro and in vivo. Neurosurgery. 54: 1231-7; discussion 1. PMID 15113479 DOI: 10.1227/01.Neu.0000119576.76193.B8 |
0.491 |
|
| 2004 |
Chung KK, Thomas B, Li X, Pletnikova O, Troncoso JC, Marsh L, Dawson VL, Dawson TM. S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function. Science (New York, N.Y.). 304: 1328-31. PMID 15105460 DOI: 10.1126/Science.1093891 |
0.679 |
|
| 2004 |
Liang D, Dawson TM, Dawson VL. What have genetically engineered mice taught us about ischemic injury? Current Molecular Medicine. 4: 207-25. PMID 15032714 DOI: 10.2174/1566524043479194 |
0.508 |
|
| 2004 |
Petrucelli L, Dickson D, Kehoe K, Taylor J, Snyder H, Grover A, De Lucia M, McGowan E, Lewis J, Prihar G, Kim J, Dillmann WH, Browne SE, Hall A, Voellmy R, ... ... Dawson TM, et al. CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation. Human Molecular Genetics. 13: 703-14. PMID 14962978 DOI: 10.1093/Hmg/Ddh083 |
0.326 |
|
| 2004 |
Hong SJ, Li H, Becker KG, Dawson VL, Dawson TM. Identification and analysis of plasticity-induced late-response genes. Proceedings of the National Academy of Sciences of the United States of America. 101: 2145-50. PMID 14766980 DOI: 10.1073/Pnas.0305170101 |
0.7 |
|
| 2004 |
Li H, Gu X, Dawson VL, Dawson TM. Identification of calcium- and nitric oxide-regulated genes by differential analysis of library expression (DAzLE). Proceedings of the National Academy of Sciences of the United States of America. 101: 647-52. PMID 14701905 DOI: 10.1073/Pnas.0305145101 |
0.53 |
|
| 2004 |
von Coelln R, Thomas B, Lim K, Hess E, Lee M, Dawson V, Dawson T. Alpha-Synuclein-induzierte Proteinaggregation und Neurodegeneration in vivo sind Parkin-unabhängig Aktuelle Neurologie. 31. DOI: 10.1055/S-2004-833018 |
0.63 |
|
| 2004 |
Dawson TM. S4-03-02 Role of parkin in defective ubiquitination and alpha-synuclein turnover in parkinson's disease Neurobiology of Aging. 25: S70. DOI: 10.1016/S0197-4580(04)80238-0 |
0.338 |
|
| 2003 |
Moore DJ, Zhang L, Dawson TM, Dawson VL. A missense mutation (L166P) in DJ-1, linked to familial Parkinson's disease, confers reduced protein stability and impairs homo-oligomerization. Journal of Neurochemistry. 87: 1558-67. PMID 14713311 DOI: 10.1111/J.1471-4159.2003.02265.X |
0.539 |
|
| 2003 |
Yu SW, Wang H, Dawson TM, Dawson VL. Poly(ADP-ribose) polymerase-1 and apoptosis inducing factor in neurotoxicity. Neurobiology of Disease. 14: 303-17. PMID 14678748 DOI: 10.1016/J.Nbd.2003.08.008 |
0.517 |
|
| 2003 |
Eriksen JL, Dawson TM, Dickson DW, Petrucelli L. Caught in the act: alpha-synuclein is the culprit in Parkinson's disease. Neuron. 40: 453-6. PMID 14642269 DOI: 10.1016/S0896-6273(03)00684-6 |
0.368 |
|
| 2003 |
Dawson TM, Dawson VL. Molecular pathways of neurodegeneration in Parkinson's disease. Science (New York, N.Y.). 302: 819-22. PMID 14593166 DOI: 10.1126/Science.1087753 |
0.606 |
|
| 2003 |
Chung KK, Dawson VL, Dawson TM. New insights into Parkinson's disease. Journal of Neurology. 250: III15-24. PMID 14579120 DOI: 10.1007/S00415-003-1304-9 |
0.583 |
|
| 2003 |
Choi P, Snyder H, Petrucelli L, Theisler C, Chong M, Zhang Y, Lim K, Chung KK, Kehoe K, D'Adamio L, Lee JM, Cochran E, Bowser R, Dawson TM, Wolozin B. SEPT5_v2 is a parkin-binding protein. Brain Research. Molecular Brain Research. 117: 179-89. PMID 14559152 DOI: 10.1016/S0169-328X(03)00318-8 |
0.631 |
|
| 2003 |
Moore DJ, Dawson VL, Dawson TM. Role for the ubiquitin-proteasome system in Parkinson's disease and other neurodegenerative brain amyloidoses. Neuromolecular Medicine. 4: 95-108. PMID 14528055 DOI: 10.1385/Nmm:4:1-2:95 |
0.605 |
|
| 2003 |
Pawlyk AC, Giasson BI, Sampathu DM, Perez FA, Lim KL, Dawson VL, Dawson TM, Palmiter RD, Trojanowski JQ, Lee VM. Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age. The Journal of Biological Chemistry. 278: 48120-8. PMID 12972409 DOI: 10.1074/Jbc.M306889200 |
0.68 |
|
| 2003 |
Moore DJ, Dawson VL, Dawson TM. Genetics of Parkinson's disease: what do mutations in DJ-1 tell us? Annals of Neurology. 54: 281-2. PMID 12953259 DOI: 10.1002/Ana.10740 |
0.523 |
|
| 2003 |
Wang H, Shimoji M, Yu SW, Dawson TM, Dawson VL. Apoptosis inducing factor and PARP-mediated injury in the MPTP mouse model of Parkinson's disease. Annals of the New York Academy of Sciences. 991: 132-9. PMID 12846982 DOI: 10.1111/J.1749-6632.2003.Tb07471.X |
0.628 |
|
| 2003 |
Lim KL, Dawson VL, Dawson TM. The cast of molecular characters in Parkinson's disease: felons, conspirators, and suspects. Annals of the New York Academy of Sciences. 991: 80-92. PMID 12846976 DOI: 10.1111/J.1749-6632.2003.Tb07465.X |
0.733 |
|
| 2003 |
Ravina BM, Fagan SC, Hart RG, Hovinga CA, Murphy DD, Dawson TM, Marler JR. Neuroprotective agents for clinical trials in Parkinson's disease: a systematic assessment. Neurology. 60: 1234-40. PMID 12707423 DOI: 10.1212/01.Wnl.0000058760.13152.1A |
0.374 |
|
| 2003 |
Fannjiang Y, Kim CH, Huganir RL, Zou S, Lindsten T, Thompson CB, Mito T, Traystman RJ, Larsen T, Griffin DE, Mandir AS, Dawson TM, Dike S, Sappington AL, Kerr DA, et al. BAK alters neuronal excitability and can switch from anti- to pro-death function during postnatal development. Developmental Cell. 4: 575-85. PMID 12689595 DOI: 10.1016/S1534-5807(03)00091-1 |
0.399 |
|
| 2003 |
Chung JW, Hong SJ, Kim KJ, Goti D, Stins MF, Shin S, Dawson VL, Dawson TM, Kim KS. 37-kDa laminin receptor precursor modulates cytotoxic necrotizing factor 1-mediated RhoA activation and bacterial uptake. The Journal of Biological Chemistry. 278: 16857-62. PMID 12615923 DOI: 10.1074/Jbc.M301028200 |
0.694 |
|
| 2003 |
Dawson TM, Dawson VL. Rare genetic mutations shed light on the pathogenesis of Parkinson disease. The Journal of Clinical Investigation. 111: 145-51. PMID 12531866 DOI: 10.1172/Jci17575 |
0.589 |
|
| 2003 |
Nucifora FC, Ellerby LM, Wellington CL, Wood JD, Herring WJ, Sawa A, Hayden MR, Dawson VL, Dawson TM, Ross CA. Nuclear localization of a non-caspase truncation product of atrophin-1, with an expanded polyglutamine repeat, increases cellular toxicity. The Journal of Biological Chemistry. 278: 13047-55. PMID 12464607 DOI: 10.1074/Jbc.M211224200 |
0.677 |
|
| 2002 |
Wei X, Sasaki M, Huang H, Dawson VL, Dawson TM. The orphan nuclear receptor, steroidogenic factor 1, regulates neuronal nitric oxide synthase gene expression in pituitary gonadotropes. Molecular Endocrinology (Baltimore, Md.). 16: 2828-39. PMID 12456803 DOI: 10.1210/Me.2001-0273 |
0.622 |
|
| 2002 |
Dawson TM, Dawson VL. Neuroprotective and neurorestorative strategies for Parkinson's disease. Nature Neuroscience. 5: 1058-61. PMID 12403986 DOI: 10.1038/Nn941 |
0.552 |
|
| 2002 |
Mandir AS, Simbulan-Rosenthal CM, Poitras MF, Lumpkin JR, Dawson VL, Smulson ME, Dawson TM. A novel in vivo post-translational modification of p53 by PARP-1 in MPTP-induced parkinsonism. Journal of Neurochemistry. 83: 186-92. PMID 12358742 DOI: 10.1046/J.1471-4159.2002.01144.X |
0.606 |
|
| 2002 |
Lim KL, Dawson VL, Dawson TM. The genetics of Parkinson's disease. Current Neurology and Neuroscience Reports. 2: 439-46. PMID 12169225 DOI: 10.1007/S11910-002-0071-9 |
0.711 |
|
| 2002 |
Dawson T, Mandir A, Lee M. Animal models of PD: pieces of the same puzzle? Neuron. 35: 219-22. PMID 12160740 DOI: 10.1016/S0896-6273(02)00780-8 |
0.364 |
|
| 2002 |
Cregan SP, Fortin A, MacLaurin JG, Callaghan SM, Cecconi F, Yu SW, Dawson TM, Dawson VL, Park DS, Kroemer G, Slack RS. Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death. The Journal of Cell Biology. 158: 507-17. PMID 12147675 DOI: 10.1083/Jcb.200202130 |
0.551 |
|
| 2002 |
Yu SW, Wang H, Poitras MF, Coombs C, Bowers WJ, Federoff HJ, Poirier GG, Dawson TM, Dawson VL. Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science (New York, N.Y.). 297: 259-63. PMID 12114629 DOI: 10.1126/Science.1072221 |
0.505 |
|
| 2002 |
Lee MK, Stirling W, Xu Y, Xu X, Qui D, Mandir AS, Dawson TM, Copeland NG, Jenkins NA, Price DL. Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 8968-73. PMID 12084935 DOI: 10.1073/Pnas.132197599 |
0.352 |
|
| 2002 |
Dawson TM, Ginty DD. CREB family transcription factors inhibit neuronal suicide. Nature Medicine. 8: 450-1. PMID 11984583 DOI: 10.1038/Nm0502-450 |
0.372 |
|
| 2002 |
Goto S, Xue R, Sugo N, Sawada M, Blizzard KK, Poitras MF, Johns DC, Dawson TM, Dawson VL, Crain BJ, Traystman RJ, Mori S, Hurn PD. Poly(ADP-ribose) polymerase impairs early and long-term experimental stroke recovery. Stroke; a Journal of Cerebral Circulation. 33: 1101-6. PMID 11935067 DOI: 10.1161/01.Str.0000014203.65693.1E |
0.484 |
|
| 2002 |
Dawson TM. Preconditioning-mediated neuroprotection through erythropoietin? Lancet. 359: 96-7. PMID 11809248 DOI: 10.1016/S0140-6736(02)07335-X |
0.321 |
|
| 2001 |
Gonzalez-Zulueta M, Dawson VL, Dawson TM. Histochemical analysis of nitric oxide synthase by NADPH diaphorase staining. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit 10.6. PMID 23045028 DOI: 10.1002/0471140856.Tx1006S01 |
0.472 |
|
| 2001 |
Dillman JF, Dawson VL, Dawson TM. Overview of the pathway and functions of nitric oxide. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit 10.1. PMID 23045023 DOI: 10.1002/0471140856.Tx1001S00 |
0.477 |
|
| 2001 |
Przedborski S, Dawson TM. The role of nitric oxide in Parkinson's disease. Methods in Molecular Medicine. 62: 113-36. PMID 21318772 DOI: 10.1385/1-59259-142-6:113 |
0.317 |
|
| 2001 |
Chung KK, Dawson VL, Dawson TM. The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders. Trends in Neurosciences. 24: S7-14. PMID 11881748 DOI: 10.1016/S0166-2236(00)01998-6 |
0.586 |
|
| 2001 |
Chung KK, Zhang Y, Lim KL, Tanaka Y, Huang H, Gao J, Ross CA, Dawson VL, Dawson TM. Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease. Nature Medicine. 7: 1144-50. PMID 11590439 DOI: 10.1038/Nm1001-1144 |
0.745 |
|
| 2001 |
Wildemann B, Haas J, Stingele K, Storch-HagenIocher B, McArthur JC, Dawson TM, Dawson VL. Identification by mRNA differential display of two up-regulated genes as candidate mediators of AIDS dementia. Molecular Medicine (Cambridge, Mass.). 7: 193-9. PMID 11471556 DOI: 10.1007/Bf03401953 |
0.502 |
|
| 2001 |
Guo X, Dillman JF, Dawson VL, Dawson TM. Neuroimmunophilins: novel neuroprotective and neuroregenerative targets. Annals of Neurology. 50: 6-16. PMID 11456311 DOI: 10.1002/Ana.1030 |
0.536 |
|
| 2001 |
Guo X, Dawson VL, Dawson TM. Neuroimmunophilin ligands exert neuroregeneration and neuroprotection in midbrain dopaminergic neurons. The European Journal of Neuroscience. 13: 1683-93. PMID 11359520 DOI: 10.1046/J.0953-816X.2001.01542.X |
0.552 |
|
| 2001 |
Tanaka Y, Engelender S, Igarashi S, Rao RK, Wanner T, Tanzi RE, Sawa A, L Dawson V, Dawson TM, Ross CA. Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis. Human Molecular Genetics. 10: 919-26. PMID 11309365 DOI: 10.1093/Hmg/10.9.919 |
0.664 |
|
| 2001 |
Nandagopal K, Dawson TM, Dawson VL. Critical role for nitric oxide signaling in cardiac and neuronal ischemic preconditioning and tolerance. The Journal of Pharmacology and Experimental Therapeutics. 297: 474-8. PMID 11303032 |
0.43 |
|
| 2001 |
Nucifora FC, Sasaki M, Peters MF, Huang H, Cooper JK, Yamada M, Takahashi H, Tsuji S, Troncoso J, Dawson VL, Dawson TM, Ross CA. Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity. Science (New York, N.Y.). 291: 2423-8. PMID 11264541 DOI: 10.1126/Science.1056784 |
0.654 |
|
| 2001 |
Mandir AS, Dawson VL, Dawson TM. Gene therapy to the rescue in Parkinson's disease. Trends in Pharmacological Sciences. 22: 103-5; discussion 10. PMID 11239561 DOI: 10.1016/S0165-6147(00)01638-2 |
0.581 |
|
| 2001 |
Aghdasi B, Ye K, Resnick A, Huang A, Ha HC, Guo X, Dawson TM, Dawson VL, Snyder SH. FKBP12, the 12-kDa FK506-binding protein, is a physiologic regulator of the cell cycle. Proceedings of the National Academy of Sciences of the United States of America. 98: 2425-30. PMID 11226255 DOI: 10.1073/Pnas.041614198 |
0.759 |
|
| 2001 |
Chiavegatto S, Dawson VL, Mamounas LA, Koliatsos VE, Dawson TM, Nelson RJ. Brain serotonin dysfunction accounts for aggression in male mice lacking neuronal nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. 98: 1277-81. PMID 11158630 DOI: 10.1073/Pnas.98.3.1277 |
0.764 |
|
| 2001 |
Zhang Y, Dawson VL, Dawson TM. Parkin: Clinical aspects and neurobiology Clinical Neuroscience Research. 1: 467-482. DOI: 10.1016/S1566-2772(01)00025-1 |
0.569 |
|
| 2001 |
Chung KK, Dawson VL, Dawson TM. The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders Trends in Neurosciences. 24: 7-14. DOI: 10.1016/S0166-2236(01)00003-0 |
0.483 |
|
| 2000 |
Dawson VL, Dawson TM. Neuronal ischaemic preconditioning. Trends in Pharmacological Sciences. 21: 423-4. PMID 11126374 DOI: 10.1016/S0165-6147(00)01560-1 |
0.529 |
|
| 2000 |
Zhang Y, Gao J, Chung KK, Huang H, Dawson VL, Dawson TM. Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1. Proceedings of the National Academy of Sciences of the United States of America. 97: 13354-9. PMID 11078524 DOI: 10.1073/Pnas.240347797 |
0.538 |
|
| 2000 |
Sampei K, Mandir AS, Asano Y, Wong PC, Traystman RJ, Dawson VL, Dawson TM, Hurn PD. Stroke outcome in double-mutant antioxidant transgenic mice. Stroke; a Journal of Cerebral Circulation. 31: 2685-91. PMID 11062295 DOI: 10.1161/01.Str.31.11.2685 |
0.505 |
|
| 2000 |
Mandir AS, Poitras MF, Berliner AR, Herring WJ, Guastella DB, Feldman A, Poirier GG, Wang ZQ, Dawson TM, Dawson VL. NMDA but not non-NMDA excitotoxicity is mediated by Poly(ADP-ribose) polymerase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 8005-11. PMID 11050121 DOI: 10.1523/Jneurosci.20-21-08005.2000 |
0.512 |
|
| 2000 |
Zhang Y, Dawson VL, Dawson TM. Oxidative stress and genetics in the pathogenesis of Parkinson's disease. Neurobiology of Disease. 7: 240-50. PMID 10964596 DOI: 10.1006/Nbdi.2000.0319 |
0.587 |
|
| 2000 |
Sasaki M, Gonzalez-Zulueta M, Huang H, Herring WJ, Ahn S, Ginty DD, Dawson VL, Dawson TM. Dynamic regulation of neuronal NO synthase transcription by calcium influx through a CREB family transcription factor-dependent mechanism. Proceedings of the National Academy of Sciences of the United States of America. 97: 8617-22. PMID 10900019 DOI: 10.1073/Pnas.97.15.8617 |
0.522 |
|
| 2000 |
Marsh L, Dawson TM. Treatment of early Parkinson's disease. Bmj (Clinical Research Ed.). 321: 1-2. PMID 10875807 DOI: 10.1136/Bmj.321.7252.1 |
0.343 |
|
| 2000 |
Dawson TM. New animal models for Parkinson's disease. Cell. 101: 115-8. PMID 10786830 DOI: 10.1016/S0092-8674(00)80629-7 |
0.438 |
|
| 2000 |
Przedborski S, Vila M, Jackson-Lewis V, Dawson TM. Reply: a new look at the pathogenesis of Parkinson's disease Trends in Pharmacological Sciences. 21: 165. PMID 10785645 DOI: 10.1016/S0165-6147(00)01470-X |
0.451 |
|
| 2000 |
Gonzalez-Zulueta M, Feldman AB, Klesse LJ, Kalb RG, Dillman JF, Parada LF, Dawson TM, Dawson VL. Requirement for nitric oxide activation of p21(ras)/extracellular regulated kinase in neuronal ischemic preconditioning. Proceedings of the National Academy of Sciences of the United States of America. 97: 436-41. PMID 10618436 DOI: 10.1073/Pnas.97.1.436 |
0.503 |
|
| 2000 |
Dawson TM. Parkinson's disease: clinical manifestations and treatment International Review of Psychiatry. 12: 263-269. DOI: 10.1080/09540260020002488 |
0.368 |
|
| 2000 |
Dawson TM. Molecular mechanisms of neuronal cell death in animal models of Parkinson's disease Neurobiology of Aging. 21: 135. DOI: 10.1016/S0197-4580(00)82408-2 |
0.414 |
|
| 1999 |
Yun HY, Dawson VL, Dawson TM. Glutamate-stimulated calcium activation of Ras/Erk pathway mediated by nitric oxide. Diabetes Research and Clinical Practice. 45: 113-5. PMID 10588362 DOI: 10.1016/S0168-8227(99)00039-X |
0.496 |
|
| 1999 |
Liberatore GT, Jackson-Lewis V, Vukosavic S, Mandir AS, Vila M, McAuliffe WG, Dawson VL, Dawson TM, Przedborski S. Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease. Nature Medicine. 5: 1403-9. PMID 10581083 DOI: 10.1038/70978 |
0.598 |
|
| 1999 |
Peters MF, Nucifora FC, Kushi J, Seaman HC, Cooper JK, Herring WJ, Dawson VL, Dawson TM, Ross CA. Nuclear targeting of mutant Huntingtin increases toxicity. Molecular and Cellular Neurosciences. 14: 121-8. PMID 10479410 DOI: 10.1006/Mcne.1999.0773 |
0.608 |
|
| 1999 |
Toung TJ, Bhardwaj A, Dawson VL, Dawson TM, Traystman RJ, Hurn PD. Neuroprotective FK506 does not alter in vivo nitric oxide production during ischemia and early reperfusion in rats. Stroke; a Journal of Cerebral Circulation. 30: 1279-85. PMID 10356112 DOI: 10.1161/01.Str.30.6.1279 |
0.473 |
|
| 1999 |
Facchinetti F, Sasaki M, Cutting FB, Zhai P, MacDonald JE, Reif D, Beal MF, Huang PL, Dawson TM, Gurney ME, Dawson VL. Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis. Neuroscience. 90: 1483-92. PMID 10338314 DOI: 10.1016/S0306-4522(98)00492-8 |
0.541 |
|
| 1999 |
Engelender S, Kaminsky Z, Guo X, Sharp AH, Amaravi RK, Kleiderlein JJ, Margolis RL, Troncoso JC, Lanahan AA, Worley PF, Dawson VL, Dawson TM, Ross CA. Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions. Nature Genetics. 22: 110-4. PMID 10319874 DOI: 10.1038/8820 |
0.72 |
|
| 1999 |
Mandir AS, Przedborski S, Jackson-Lewis V, Wang ZQ, Simbulan-Rosenthal CM, Smulson ME, Hoffman BE, Guastella DB, Dawson VL, Dawson TM. Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. 96: 5774-9. PMID 10318960 DOI: 10.1073/Pnas.96.10.5774 |
0.617 |
|
| 1999 |
Adamson DC, McArthur JC, Dawson TM, Dawson VL. Rate and severity of HIV-associated dementia (HAD): correlations with Gp41 and iNOS. Molecular Medicine (Cambridge, Mass.). 5: 98-109. PMID 10203575 DOI: 10.1007/Bf03402144 |
0.466 |
|
| 1999 |
Kriegsfeld LJ, Eliasson MJ, Demas GE, Blackshaw S, Dawson TM, Nelson RJ, Snyder SH. Nocturnal motor coordination deficits in neuronal nitric oxide synthase knock-out mice. Neuroscience. 89: 311-5. PMID 10077313 DOI: 10.1016/S0306-4522(98)00614-9 |
0.807 |
|
| 1999 |
Kriegsfeld LJ, Demas GE, Lee SE, Dawson TM, Dawson VL, Nelson RJ. Circadian locomotor analysis of male mice lacking the gene for neuronal nitric oxide synthase (nNOS-/-) Journal of Biological Rhythms. 14: 20-7. PMID 10036989 DOI: 10.1177/074873099129000407 |
0.599 |
|
| 1999 |
Xu KY, Huso DL, Dawson TM, Bredt DS, Becker LC. Nitric oxide synthase in cardiac sarcoplasmic reticulum. Proceedings of the National Academy of Sciences of the United States of America. 96: 657-62. PMID 9892689 DOI: 10.1073/Pnas.96.2.657 |
0.517 |
|
| 1999 |
Adamson DC, Kopnisky KL, Dawson TM, Dawson VL. Mechanisms and structural determinants of HIV-1 coat protein, gp41-induced neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 64-71. PMID 9870939 DOI: 10.1523/Jneurosci.19-01-00064.1999 |
0.521 |
|
| 1998 |
Dawson VL, Dawson TM. Nitric oxide in neurodegeneration. Progress in Brain Research. 118: 215-29. PMID 9932444 DOI: 10.1016/S0079-6123(08)63210-0 |
0.557 |
|
| 1998 |
Dawson TM, Sasaki M, Gonzalez-Zulueta M, Dawson VL. Regulation of neuronal nitric oxide synthase and identification of novel nitric oxide signaling pathways. Progress in Brain Research. 118: 3-11. PMID 9932430 DOI: 10.1016/S0079-6123(08)63196-9 |
0.554 |
|
| 1998 |
Facchinetti F, Dawson VL, Dawson TM. Free radicals as mediators of neuronal injury. Cellular and Molecular Neurobiology. 18: 667-82. PMID 9876873 DOI: 10.1023/A:1020685903186 |
0.529 |
|
| 1998 |
Klein SL, Carnovale D, Burnett AL, Wallach EE, Zacur HA, Crone JK, Dawson VL, Nelson RJ, Dawson TM. Impaired ovulation in mice with targeted deletion of the neuronal isoform of nitric oxide synthase. Molecular Medicine (Cambridge, Mass.). 4: 658-64. PMID 9848082 DOI: 10.1007/Bf03401926 |
0.592 |
|
| 1998 |
Jumrussirikul P, Dinerman J, Dawson TM, Dawson VL, Ekelund U, Georgakopoulos D, Schramm LP, Calkins H, Snyder SH, Hare JM, Berger RD. Interaction between neuronal nitric oxide synthase and inhibitory G protein activity in heart rate regulation in conscious mice. The Journal of Clinical Investigation. 102: 1279-85. PMID 9769319 DOI: 10.1172/Jci2843 |
0.631 |
|
| 1998 |
Walensky LD, Dawson TM, Steiner JP, Sabatini DM, Suarez JD, Klinefelter GR, Snyder SH. The 12 kD FK 506 binding protein FKBP12 is released in the male reproductive tract and stimulates sperm motility. Molecular Medicine (Cambridge, Mass.). 4: 502-14. PMID 9742506 |
0.621 |
|
| 1998 |
Yun HY, Gonzalez-Zulueta M, Dawson VL, Dawson TM. Nitric oxide mediates N-methyl-D-aspartate receptor-induced activation of p21ras. Proceedings of the National Academy of Sciences of the United States of America. 95: 5773-8. PMID 9576960 DOI: 10.1073/Pnas.95.10.5773 |
0.507 |
|
| 1998 |
Crosbie RH, Straub V, Yun HY, Lee JC, Rafael JA, Chamberlain JS, Dawson VL, Dawson TM, Campbell KP. mdx muscle pathology is independent of nNOS perturbation. Human Molecular Genetics. 7: 823-9. PMID 9536086 DOI: 10.1093/Hmg/7.5.823 |
0.479 |
|
| 1998 |
Cooper JK, Schilling G, Peters MF, Herring WJ, Sharp AH, Kaminsky Z, Masone J, Khan FA, Delanoy M, Borchelt DR, Dawson VL, Dawson TM, Ross CA. Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture. Human Molecular Genetics. 7: 783-90. PMID 9536081 DOI: 10.1093/Hmg/7.5.783 |
0.616 |
|
| 1998 |
Gonzalez-Zulueta M, Ensz LM, Mukhina G, Lebovitz RM, Zwacka RM, Engelhardt JF, Oberley LW, Dawson VL, Dawson TM. Manganese superoxide dismutase protects nNOS neurons from NMDA and nitric oxide-mediated neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 2040-55. PMID 9482791 DOI: 10.1523/Jneurosci.18-06-02040.1998 |
0.54 |
|
| 1998 |
Weiss SW, Albers DS, Iadarola MJ, Dawson TM, Dawson VL, Standaert DG. NMDAR1 glutamate receptor subunit isoforms in neostriatal, neocortical, and hippocampal nitric oxide synthase neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 1725-34. PMID 9464997 DOI: 10.1523/Jneurosci.18-05-01725.1998 |
0.547 |
|
| 1998 |
Gonzalez-Zulueta M, Ensz LM, Mukhina G, Lebovitz RM, Zwacka RM, Engelhardt JF, Oberley LW, Dawson VL, Dawson TM. Manganese Superoxide Dismutase Protects nNOS Neurons from NMDA and Nitric Oxide-Mediated Neurotoxicity The Journal of Neuroscience. 18: 2040-2055. DOI: 10.1523/JNEUROSCI.18-06-02040.1998 |
0.465 |
|
| 1998 |
Dawson TM, Gonzalez-ZuluetaS M, Kusel J, Dawson VL. Nitric Oxide: Diverse Actions in the Central and Peripheral Nervous Systems The Neuroscientist. 4: 96-112. DOI: 10.1177/107385849800400206 |
0.502 |
|
| 1998 |
Warner DS, Eliasson MJ, Sampei K, Mandir AS, Hum PD, Traystman RJ, Bao J, Pieper A, Wang Z, Dawson TM, Snyder SH, Dawson VL. Journal Club Journal of Neurosurgical Anesthesiology. 10: 124. DOI: 10.1097/00008506-199804000-00012 |
0.647 |
|
| 1998 |
Walensky LD, Dawson TM, Steiner JP, Sabatini DM, Suarez JD, Klinefelter GR, Snyder SH. The 12 kD FK506 Binding Protein FKBP12 Is Released in the Male Reproductive Tract and Stimulates Sperm Motility Molecular Medicine. 4: 502-514. DOI: 10.1007/Bf03401755 |
0.71 |
|
| 1997 |
Kriegsfeld LJ, Dawson TM, Dawson VL, Nelson RJ, Snyder SH. Aggressive behavior in male mice lacking the gene for neuronal nitric oxide synthase requires testosterone. Brain Research. 769: 66-70. PMID 9374274 DOI: 10.1016/S0006-8993(97)00688-4 |
0.664 |
|
| 1997 |
Nelson RJ, Kriegsfeld LJ, Dawson VL, Dawson TM. Effects of nitric oxide on neuroendocrine function and behavior. Frontiers in Neuroendocrinology. 18: 463-91. PMID 9344634 DOI: 10.1006/Frne.1997.0156 |
0.572 |
|
| 1997 |
Eliasson MJ, Sampei K, Mandir AS, Hurn PD, Traystman RJ, Bao J, Pieper A, Wang ZQ, Dawson TM, Snyder SH, Dawson VL. Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia. Nature Medicine. 3: 1089-95. PMID 9334719 DOI: 10.1038/Nm1097-1089 |
0.804 |
|
| 1997 |
Demas GE, Eliasson MJ, Dawson TM, Dawson VL, Kriegsfeld LJ, Nelson RJ, Snyder SH. Inhibition of neuronal nitric oxide synthase increases aggressive behavior in mice. Molecular Medicine (Cambridge, Mass.). 3: 610-6. PMID 9323712 DOI: 10.1007/Bf03401818 |
0.793 |
|
| 1997 |
Yun HY, Dawson VL, Dawson TM. Nitric oxide in health and disease of the nervous system. Molecular Psychiatry. 2: 300-10. PMID 9246670 |
0.491 |
|
| 1997 |
Samdani AF, Dawson TM, Dawson VL. Nitric oxide synthase in models of focal ischemia. Stroke; a Journal of Cerebral Circulation. 28: 1283-8. PMID 9183363 DOI: 10.1161/01.Str.28.6.1283 |
0.527 |
|
| 1997 |
Samdani AF, Newcamp C, Resink A, Facchinetti F, Hoffman BE, Dawson VL, Dawson TM. Differential susceptibility to neurotoxicity mediated by neurotrophins and neuronal nitric oxide synthase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 4633-41. PMID 9169524 DOI: 10.1523/Jneurosci.17-12-04633.1997 |
0.545 |
|
| 1997 |
Burnett AL, Calvin DC, Chamness SL, Liu JX, Nelson RJ, Klein SL, Dawson VL, Dawson TM, Snyder SH. Urinary bladder-urethral sphincter dysfunction in mice with targeted disruption of neuronal nitric oxide synthase models idiopathic voiding disorders in humans. Nature Medicine. 3: 571-4. PMID 9142130 DOI: 10.1038/Nm0597-571 |
0.681 |
|
| 1997 |
Togashi H, Sasaki M, Frohman E, Taira E, Ratan RR, Dawson TM, Dawson VL. Neuronal (type I) nitric oxide synthase regulates nuclear factor kappaB activity and immunologic (type II) nitric oxide synthase expression. Proceedings of the National Academy of Sciences of the United States of America. 94: 2676-80. PMID 9122255 DOI: 10.1073/Pnas.94.6.2676 |
0.511 |
|
| 1997 |
Aoki C, Rhee J, Lubin M, Dawson TM. NMDA-R1 subunit of the cerebral cortex co-localizes with neuronal nitric oxide synthase at pre- and postsynaptic sites and in spines. Brain Research. 750: 25-40. PMID 9098526 DOI: 10.1016/S0006-8993(96)01147-X |
0.309 |
|
| 1997 |
Steiner JP, Connolly MA, Valentine HL, Hamilton GS, Dawson TM, Hester L, Snyder SH. Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A. Nature Medicine. 3: 421-8. PMID 9095176 DOI: 10.1038/Nm0497-421 |
0.523 |
|
| 1996 |
Dawson VL, Dawson TM. Free radicals and neuronal cell death. Cell Death and Differentiation. 3: 71-8. PMID 17180057 |
0.425 |
|
| 1996 |
Karson CN, Griffin WS, Mrak RE, Husain M, Dawson TM, Snyder SH, Moore NC, Sturner WQ. Nitric oxide synthase (NOS) in schizophrenia: increases in cerebellar vermis. Molecular and Chemical Neuropathology / Sponsored by the International Society For Neurochemistry and the World Federation of Neurology and Research Groups On Neurochemistry and Cerebrospinal Fluid. 27: 275-84. PMID 9147413 DOI: 10.1007/Bf02815109 |
0.503 |
|
| 1996 |
Yun HY, Dawson VL, Dawson TM. Neurobiology of nitric oxide. Critical Reviews in Neurobiology. 10: 291-316. PMID 8978984 DOI: 10.1615/Critrevneurobiol.V10.I3-4.20 |
0.504 |
|
| 1996 |
Adamson DC, Wildemann B, Sasaki M, Glass JD, McArthur JC, Christov VI, Dawson TM, Dawson VL. Immunologic NO synthase: elevation in severe AIDS dementia and induction by HIV-1 gp41. Science (New York, N.Y.). 274: 1917-21. PMID 8943206 DOI: 10.1126/Science.274.5294.1917 |
0.487 |
|
| 1996 |
Ruthazer ES, Gillespie DC, Dawson TM, Snyder SH, Stryker MP. Inhibition of nitric oxide synthase does not prevent ocular dominance plasticity in kitten visual cortex. The Journal of Physiology. 494: 519-27. PMID 8842009 DOI: 10.1113/Jphysiol.1996.Sp021510 |
0.419 |
|
| 1996 |
Dawson VL, Dawson TM. Nitric oxide actions in neurochemistry. Neurochemistry International. 29: 97-110. PMID 8837037 DOI: 10.1016/0197-0186(95)00149-2 |
0.535 |
|
| 1996 |
Adamson DC, Dawson TM, Zink MC, Clements JE, Dawson VL. Neurovirulent simian immunodeficiency virus infection induces neuronal, endothelial, and glial apoptosis. Molecular Medicine (Cambridge, Mass.). 2: 417-28. PMID 8827712 DOI: 10.1007/Bf03401901 |
0.521 |
|
| 1996 |
Dawson VL, Dawson TM. Nitric oxide neurotoxicity. Journal of Chemical Neuroanatomy. 10: 179-90. PMID 8811421 DOI: 10.1016/0891-0618(96)00148-2 |
0.548 |
|
| 1996 |
Lam HH, Hanley DF, Trapp BD, Saito S, Raja S, Dawson TM, Yamaguchi H. Induction of spinal cord neuronal nitric oxide synthase (NOS) after formalin injection in the rat hind paw. Neuroscience Letters. 210: 201-4. PMID 8805130 DOI: 10.1016/0304-3940(96)12702-6 |
0.307 |
|
| 1996 |
Dawson VL, Kizushi VM, Huang PL, Snyder SH, Dawson TM. Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 2479-87. PMID 8786424 |
0.459 |
|
| 1996 |
Burnett AL, Nelson RJ, Calvin DC, Liu JX, Demas GE, Klein SL, Kriegsfeld LJ, Dawson VL, Dawson TM, Snyder SH. Nitric oxide-dependent penile erection in mice lacking neuronal nitric oxide synthase. Molecular Medicine (Cambridge, Mass.). 2: 288-96. PMID 8784782 DOI: 10.1007/Bf03401627 |
0.691 |
|
| 1996 |
Dawson TM, Dawson VL. Generation of isoform-specific antibodies to nitric oxide synthases. Methods in Enzymology. 268: 349-58. PMID 8782601 DOI: 10.1016/S0076-6879(96)68037-9 |
0.453 |
|
| 1996 |
Dawson TM, Dawson VL. Nitric oxide synthase: role as a transmitter/mediator in the brain and endocrine system. Annual Review of Medicine. 47: 219-27. PMID 8712777 DOI: 10.1146/Annurev.Med.47.1.219 |
0.495 |
|
| 1996 |
Xia Y, Dawson VL, Dawson TM, Snyder SH, Zweier JL. Nitric oxide synthase generates superoxide and nitric oxide in arginine-depleted cells leading to peroxynitrite-mediated cellular injury. Proceedings of the National Academy of Sciences of the United States of America. 93: 6770-4. PMID 8692893 DOI: 10.1073/Pnas.93.13.6770 |
0.604 |
|
| 1996 |
Bao J, Sharp AH, Wagster MV, Becher M, Schilling G, Ross CA, Dawson VL, Dawson TM. Expansion of polyglutamine repeat in huntingtin leads to abnormal protein interactions involving calmodulin. Proceedings of the National Academy of Sciences of the United States of America. 93: 5037-42. PMID 8643525 DOI: 10.1073/Pnas.93.10.5037 |
0.601 |
|
| 1996 |
Li XJ, Sharp AH, Li SH, Dawson TM, Snyder SH, Ross CA. Huntingtin-associated protein (HAP1): discrete neuronal localizations in the brain resemble those of neuronal nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. 93: 4839-44. PMID 8643490 DOI: 10.1073/Pnas.93.10.4839 |
0.663 |
|
| 1996 |
Przedborski S, Jackson-Lewis V, Yokoyama R, Shibata T, Dawson VL, Dawson TM. Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 93: 4565-71. PMID 8643444 DOI: 10.1073/Pnas.93.10.4565 |
0.612 |
|
| 1996 |
Pluta RM, Thompson BG, Dawson TM, Snyder SH, Boock RJ, Oldfield EH. Loss of nitric oxide synthase immunoreactivity in cerebral vasospasm. Journal of Neurosurgery. 84: 648-54. PMID 8613858 DOI: 10.3171/Jns.1996.84.4.0648 |
0.476 |
|
| 1996 |
Dawson VL, Dawson TM. Nitric oxide in neuronal degeneration. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 211: 33-40. PMID 8594616 DOI: 10.3181/00379727-211-43950E |
0.551 |
|
| 1996 |
Resink A, Dawson VL, Dawson TM. Nitric Oxide Synthase Inhibitors Cns Drugs. 6: 351-357. DOI: 10.2165/00023210-199606050-00002 |
0.502 |
|
| 1996 |
Dawson V, Kizushi V, Huang P, Snyder S, Dawson T. Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase-deficient mice The Journal of Neuroscience. 16: 2479-2487. DOI: 10.1523/Jneurosci.16-08-02479.1996 |
0.638 |
|
| 1996 |
Dawson VL, Dawson TM. [2] Nitric oxide toxicity in central nervous system cultures Methods in Neurosciences. 30: 26-43. DOI: 10.1016/S1043-9471(96)80094-2 |
0.464 |
|
| 1996 |
Dawson VL, Dawson TM. [20] Function of nitric oxide in neuronal cell death Methods in Neurosciences. 31: 228-240. DOI: 10.1016/S1043-9471(96)80023-1 |
0.539 |
|
| 1996 |
Dawson TM, Dawson VL. [6] NADPH Diaphorase staining Methods in Neurosciences. 31: 62-67. DOI: 10.1016/S1043-9471(96)80009-7 |
0.448 |
|
| 1996 |
Steiner JP, Dawson TM, Fotuhi M, Snyder SH. Immunophilin Regulation of Neurotransmitter Release Molecular Medicine. 2: 325-333. DOI: 10.1007/Bf03401630 |
0.522 |
|
| 1995 |
Dawson VL, Dawson TM. Physiological and toxicological actions of nitric oxide in the central nervous system. Advances in Pharmacology (San Diego, Calif.). 34: 323-42. PMID 8562443 DOI: 10.1016/S1054-3589(08)61095-9 |
0.539 |
|
| 1995 |
Dawson TM, Dawson VL. ADP-ribosylation as a mechanism for the action of nitric oxide in the nervous system. New Horizons (Baltimore, Md.). 3: 85-92. PMID 7704595 |
0.493 |
|
| 1995 |
Linden DJ, Dawson TM, Dawson VL. An evaluation of the nitric oxide/cGMP/cGMP-dependent protein kinase cascade in the induction of cerebellar long-term depression in culture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 5098-105. PMID 7623138 DOI: 10.1523/Jneurosci.15-07-05098.1995 |
0.519 |
|
| 1995 |
Irikura K, Huang PL, Ma J, Lee WS, Dalkara T, Fishman MC, Dawson TM, Snyder SH, Moskowitz MA. Cerebrovascular alterations in mice lacking neuronal nitric oxide synthase gene expression. Proceedings of the National Academy of Sciences of the United States of America. 92: 6823-7. PMID 7542777 DOI: 10.1073/Pnas.92.15.6823 |
0.536 |
|
| 1995 |
Dawson TM, Hung K, Dawson VL, Steiner JP, Snyder SH. Neuroprotective effects of gangliosides may involve inhibition of nitric oxide synthase. Annals of Neurology. 37: 115-8. PMID 7529474 DOI: 10.1002/Ana.410370122 |
0.63 |
|
| 1995 |
Nelson RJ, Demas GE, Huang PL, Fishman MC, Dawson VL, Dawson TM, Snyder SH. Behavioural abnormalities in male mice lacking neuronal nitric oxide synthase. Nature. 378: 383-6. PMID 7477374 DOI: 10.1038/378383A0 |
0.685 |
|
| 1995 |
Lyons W, Steiner J, Snyder S, Dawson T. Neuronal regeneration enhances the expression of the immunophilin FKBP- 12 The Journal of Neuroscience. 15: 2985-2994. DOI: 10.1523/Jneurosci.15-04-02985.1995 |
0.53 |
|
| 1995 |
Dawson TM, Dawson VL. Review ■ Nitric Oxide: Actions and Pathological Roles The Neuroscientist. 1: 7-18. DOI: 10.1177/107385849500100103 |
0.508 |
|
| 1994 |
Zhang J, Dawson VL, Dawson TM, Snyder SH. Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity. Science (New York, N.Y.). 263: 687-9. PMID 8080500 DOI: 10.1126/Science.8080500 |
0.631 |
|
| 1994 |
Dawson VL, Hsu CY, Liu TH, Dawson TM, Wamsley JK. Receptor alterations in subcortical structures after bilateral middle cerebral artery infarction of the cerebral cortex. Experimental Neurology. 128: 88-96. PMID 8070526 DOI: 10.1006/Exnr.1994.1115 |
0.479 |
|
| 1994 |
Lynch DR, Dawson TM. Secondary mechanisms in neuronal trauma Current Opinion in Neurology. 7: 510-516. PMID 7866582 DOI: 10.1097/00019052-199412000-00007 |
0.482 |
|
| 1994 |
Dawson TM, Dawson VL, Snyder SH. Molecular mechanisms of nitric oxide actions in the brain. Annals of the New York Academy of Sciences. 738: 76-85. PMID 7832458 DOI: 10.1111/J.1749-6632.1994.Tb21792.X |
0.598 |
|
| 1994 |
Dawson TM, Zhang J, Dawson VL, Snyder SH. Nitric oxide: cellular regulation and neuronal injury. Progress in Brain Research. 103: 365-9. PMID 7533914 DOI: 10.1016/S0079-6123(08)61150-4 |
0.66 |
|
| 1994 |
Dawson TM, Dawson VL. gp120 neurotoxicity in primary cortical cultures. Advances in Neuroimmunology. 4: 167-73. PMID 7533039 DOI: 10.1016/S0960-5428(06)80253-6 |
0.491 |
|
| 1994 |
Dawson VL, Brahmbhatt HP, Mong JA, Dawson TM. Expression of inducible nitric oxide synthase causes delayed neurotoxicity in primary mixed neuronal-glial cortical cultures. Neuropharmacology. 33: 1425-30. PMID 7532825 DOI: 10.1016/0028-3908(94)90045-0 |
0.52 |
|
| 1994 |
Dinerman JL, Steiner JP, Dawson TM, Dawson V, Snyder SH. Cyclic nucleotide dependent phosphorylation of neuronal nitric oxide synthase inhibits catalytic activity. Neuropharmacology. 33: 1245-51. PMID 7532810 DOI: 10.1016/0028-3908(94)90023-X |
0.634 |
|
| 1994 |
Wu W, Liuzzi FJ, Schinco FP, Depto AS, Li Y, Mong JA, Dawson TM, Snyder SH. Neuronal nitric oxide synthase is induced in spinal neurons by traumatic injury. Neuroscience. 61: 719-26. PMID 7530816 DOI: 10.1016/0306-4522(94)90394-8 |
0.547 |
|
| 1994 |
Kovách AG, Lohinai Z, Marczis J, Balla I, Dawson TM, Snyder SH. The effect of hemorrhagic hypotension and retransfusion and 7-nitro-indazole on rCBF, NOS catalytic activity, and cortical NO content in the cat. Annals of the New York Academy of Sciences. 738: 348-68. PMID 7530422 DOI: 10.1111/j.1749-6632.1994.tb21822.x |
0.396 |
|
| 1994 |
Dawson TM, Steiner JP, Lyons WE, Fotuhi M, Blue M, Snyder SH. The immunophilins, FK506 binding protein and cyclophilin, are discretely localized in the brain: relationship to calcineurin. Neuroscience. 62: 569-80. PMID 7530348 DOI: 10.1016/0306-4522(94)90389-1 |
0.502 |
|
| 1994 |
Roskams AJ, Bredt DS, Dawson TM, Ronnett GV. Nitric oxide mediates the formation of synaptic connections in developing and regenerating olfactory receptor neurons. Neuron. 13: 289-99. PMID 7520251 DOI: 10.1016/0896-6273(94)90347-6 |
0.554 |
|
| 1994 |
O'Dell TJ, Huang PL, Dawson TM, Dinerman JL, Snyder SH, Kandel ER, Fishman MC. Endothelial NOS and the blockade of LTP by NOS inhibitors in mice lacking neuronal NOS. Science (New York, N.Y.). 265: 542-6. PMID 7518615 DOI: 10.1126/Science.7518615 |
0.531 |
|
| 1994 |
Saito S, Kidd GJ, Trapp BD, Dawson TM, Bredt DS, Wilson DA, Traystman RJ, Snyder SH, Hanley DF. Rat spinal cord neurons contain nitric oxide synthase. Neuroscience. 59: 447-56. PMID 7516502 DOI: 10.1016/0306-4522(94)90608-4 |
0.653 |
|
| 1994 |
Dinerman JL, Dawson TM, Schell MJ, Snowman A, Snyder SH. Endothelial nitric oxide synthase localized to hippocampal pyramidal cells: implications for synaptic plasticity. Proceedings of the National Academy of Sciences of the United States of America. 91: 4214-8. PMID 7514300 DOI: 10.1073/Pnas.91.10.4214 |
0.642 |
|
| 1994 |
Lyons WE, George EB, Dawson TM, Steiner JP, Snyder SH. Immunosuppressant FK506 promotes neurite outgrowth in cultures of PC12 cells and sensory ganglia. Proceedings of the National Academy of Sciences of the United States of America. 91: 3191-5. PMID 7512727 DOI: 10.1073/Pnas.91.8.3191 |
0.511 |
|
| 1994 |
Dawson T, Snyder S. Gases as biological messengers: nitric oxide and carbon monoxide in the brain The Journal of Neuroscience. 14: 5147-5159. DOI: 10.1523/Jneurosci.14-09-05147.1994 |
0.526 |
|
| 1993 |
Hirsch DB, Steiner JP, Dawson TM, Mammen A, Hayek E, Snyder SH. Neurotransmitter release regulated by nitric oxide in PC-12 cells and brain synaptosomes. Current Biology : Cb. 3: 749-54. PMID 15335838 DOI: 10.1016/0960-9822(93)90022-G |
0.517 |
|
| 1993 |
Sharp AH, Dawson TM, Ross CA, Fotuhi M, Mourey RJ, Snyder SH. Inositol 1,4,5-trisphosphate receptors: immunohistochemical localization to discrete areas of rat central nervous system. Neuroscience. 53: 927-42. PMID 8389431 DOI: 10.1016/0306-4522(93)90478-X |
0.596 |
|
| 1993 |
Dawson VL, Dawson TM, Uhl GR, Snyder SH. Human immunodeficiency virus type 1 coat protein neurotoxicity mediated by nitric oxide in primary cortical cultures. Proceedings of the National Academy of Sciences of the United States of America. 90: 3256-9. PMID 8097316 DOI: 10.1073/Pnas.90.8.3256 |
0.625 |
|
| 1993 |
Dawson TM, Steiner JP, Dawson VL, Dinerman JL, Uhl GR, Snyder SH. Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 90: 9808-12. PMID 7694293 DOI: 10.1073/Pnas.90.21.9808 |
0.626 |
|
| 1993 |
Dawson VL, Dawson TM, Bartley DA, Uhl GR, Snyder SH. Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 2651-61. PMID 7684776 DOI: 10.1523/Jneurosci.13-06-02651.1993 |
0.543 |
|
| 1993 |
Nozaki K, Moskowitz MA, Maynard KI, Koketsu N, Dawson TM, Bredt DS, Snyder SH. Possible origins and distribution of immunoreactive nitric oxide synthase-containing nerve fibers in cerebral arteries. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 13: 70-9. PMID 7678014 DOI: 10.1038/Jcbfm.1993.9 |
0.628 |
|
| 1993 |
Yamamoto R, Bredt DS, Dawson TM, Snyder SH, Stone RA. Enhanced expression of nitric oxide synthase by rat retina following pterygopalatine parasympathetic denervation. Brain Research. 631: 83-8. PMID 7507791 DOI: 10.1016/0006-8993(93)91190-4 |
0.62 |
|
| 1993 |
Dawson TM, Dawson VL, Snyder SH. Nitric oxide as a mediator of neurotoxicity. Nida Research Monograph. 136: 258-71; discussion 2. PMID 7507221 |
0.402 |
|
| 1993 |
Huang PL, Dawson TM, Bredt DS, Snyder SH, Fishman MC. Targeted disruption of the neuronal nitric oxide synthase gene. Cell. 75: 1273-86. PMID 7505721 DOI: 10.1016/0092-8674(93)90615-W |
0.687 |
|
| 1993 |
Fotuhi M, Dawson T, Sharp A, Martin L, Graybiel A, Snyder S. Phosphoinositide second messenger system is enriched in striosomes: immunohistochemical demonstration of inositol 1,4,5-trisphosphate receptors and phospholipase C beta and gamma in primate basal ganglia The Journal of Neuroscience. 13: 3300-3308. DOI: 10.1523/Jneurosci.13-08-03300.1993 |
0.53 |
|
| 1993 |
Sharp A, McPherson P, Dawson T, Aoki C, Campbell K, Snyder S. Differential immunohistochemical localization of inositol 1,4,5- trisphosphate- and ryanodine-sensitive Ca2+ release channels in rat brain The Journal of Neuroscience. 13: 3051-3063. DOI: 10.1523/Jneurosci.13-07-03051.1993 |
0.491 |
|
| 1993 |
Dawson V, Dawson T, Bartley D, Uhl G, Snyder S. Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures The Journal of Neuroscience. 13: 2651-2661. DOI: 10.1523/JNEUROSCI.13-06-02651.1993 |
0.565 |
|
| 1993 |
Fotuhi M, Sharp A, Glatt C, Hwang P, von Krosigk M, Snyder S, Dawson T. Differential localization of phosphoinositide-linked metabotropic glutamate receptor (mGluR1) and the inositol 1,4,5-trisphosphate receptor in rat brain The Journal of Neuroscience. 13: 2001-2012. DOI: 10.1523/Jneurosci.13-05-02001.1993 |
0.52 |
|
| 1992 |
Dawson TM, Dawson VL, Snyder SH. A novel neuronal messenger molecule in brain: the free radical, nitric oxide. Annals of Neurology. 32: 297-311. PMID 1384420 DOI: 10.1002/Ana.410320302 |
0.647 |
|
| 1992 |
Steiner JP, Dawson TM, Fotuhi M, Glatt CE, Snowman AM, Cohen N, Snyder SH. High brain densities of the immunophilin FKBP colocalized with calcineurin. Nature. 358: 584-7. PMID 1380130 DOI: 10.1038/358584A0 |
0.697 |
|
| 1992 |
Lynch DR, Dawson TM, Raps EC, Galetta SL. Risk Factors for the Neurologic Complications Associated with Aortic Aneurysms Archives of Neurology. 49: 284-288. PMID 1311168 DOI: 10.1001/Archneur.1992.00530270098025 |
0.339 |
|
| 1992 |
Hyman BT, Marzloff K, Wenniger JJ, Dawson TM, Bredt DS, Snyder SH. Relative sparing of nitric oxide synthase-containing neurons in the hippocampal formation in Alzheimer's disease. Annals of Neurology. 32: 818-20. PMID 1281971 DOI: 10.1002/Ana.410320618 |
0.695 |
|
| 1991 |
Dawson TM, Dawson VL, Gage FH, Fisher LJ, Hunt MA, Wamsley JK. Downregulation of muscarinic receptors in the rat caudate-putamen after lesioning of the ipsilateral nigrostriatal dopamine pathway with 6-hydroxydopamine (6-OHDA): normalization by fetal mesencephalic transplants. Brain Research. 540: 145-52. PMID 1905173 DOI: 10.1016/0006-8993(91)90501-L |
0.388 |
|
| 1991 |
Dawson TM, Dawson VL, Gage FH, Fisher LJ, Hunt MA, Wamsley JK. Functional recovery of supersensitive dopamine receptors after intrastriatal grafts of fetal substantia nigra. Experimental Neurology. 111: 282-92. PMID 1825638 DOI: 10.1016/0014-4886(91)90095-T |
0.417 |
|
| 1991 |
Wamsley JK, Dawson TM, Dawson VL, Hunt MA, Fisher LJ, Gage FH. Reversal of nigrostriatal-lesion-induced receptor alterations by grafting of fetal mesencephalic dopaminergic neurons. Advances in Experimental Medicine and Biology. 287: 221-35. PMID 1759609 DOI: 10.1007/978-1-4684-5907-4_18 |
0.434 |
|
| 1991 |
Bredt DS, Glatt CE, Hwang PM, Fotuhi M, Dawson TM, Snyder SH. Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase. Neuron. 7: 615-24. PMID 1718335 DOI: 10.1016/0896-6273(91)90374-9 |
0.764 |
|
| 1991 |
Dawson TM, Bredt DS, Fotuhi M, Hwang PM, Snyder SH. Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues. Proceedings of the National Academy of Sciences of the United States of America. 88: 7797-801. PMID 1715581 DOI: 10.1073/Pnas.88.17.7797 |
0.685 |
|
| 1991 |
Dawson VL, Dawson TM, London ED, Bredt DS, Snyder SH. Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures. Proceedings of the National Academy of Sciences of the United States of America. 88: 6368-71. PMID 1648740 DOI: 10.1073/Pnas.88.14.6368 |
0.705 |
|
| 1990 |
Dawson VL, Dawson TM, Wamsley JK. Muscarinic and dopaminergic receptor subtypes on striatal cholinergic interneurons. Brain Research Bulletin. 25: 903-12. PMID 2149667 DOI: 10.1016/0361-9230(90)90186-4 |
0.415 |
|
| 1988 |
Dawson VL, Dawson TM, Filloux FM, Wamsley JK. Evidence for dopamine D-2 receptors on cholinergic interneurons in the rat caudate-putamen. Life Sciences. 42: 1933-9. PMID 2966886 DOI: 10.1016/0024-3205(88)90492-4 |
0.408 |
|
| 1985 |
Gehlert DR, Dawson TM, Yamamura HI, Wamsley JK. Quantitative autoradiography of [3H]forskolin binding sites in the rat brain. Brain Research. 361: 351-60. PMID 4084804 DOI: 10.1016/0006-8993(85)91305-8 |
0.386 |
|
| 1985 |
Dawson TM, Gehlert DR, Yamamura HI, Barnett A, Wamsley JK. D-1 dopamine receptors in the rat brain: autoradiographic localization using [3H]SCH 23390. European Journal of Pharmacology. 108: 323-5. PMID 3886408 DOI: 10.1016/0014-2999(85)90458-3 |
0.355 |
|
| 1984 |
Gehlert DR, Dawson TM, Yamamura HI, Wamsley JK. Localization of [3H]forskolin binding sites in the rat brain using quantitative autoradiography. European Journal of Pharmacology. 106: 223-5. PMID 6543336 DOI: 10.1016/0014-2999(84)90707-6 |
0.333 |
|
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