Chengyu Liang, Ph.D. - Publications

Affiliations: 
Stony Brook University, Stony Brook, NY, United States 

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Choi HY, Siddique HR, Zheng M, Kou Y, Yeh DW, Machida T, Chen CL, Uthaya Kumar DB, Punj V, Winer P, Pita A, Sher L, Tahara SM, Ray RB, Liang C, et al. p53 destabilizing protein skews asymmetric division and enhances NOTCH activation to direct self-renewal of TICs. Nature Communications. 11: 3084. PMID 32555153 DOI: 10.1038/S41467-020-16616-8  0.328
2020 Zhu Q, Wang R, Nemecio D, Liang C. How autophagy is tied to inflammation and cancer. Molecular & Cellular Oncology. 7: 1717908. PMID 32158928 DOI: 10.1080/23723556.2020.1717908  0.304
2020 Castro-Gonzalez S, Shi Y, Colomer-Lluch M, Song Y, Mowery K, Almodovar S, Bansal A, Kirchhoff F, Sparrer K, Liang C, Serra-Moreno R. HIV-1 Nef counteracts autophagy restriction by enhancing the association between BECN1 and its inhibitor BCL2 in a PRKN-dependent manner. Autophagy. 1-25. PMID 32097085 DOI: 10.1080/15548627.2020.1725401  0.344
2020 Song Y, Quach C, Liang C. UVRAG in autophagy, inflammation, and cancer. Autophagy. 1-2. PMID 31905312 DOI: 10.1080/15548627.2019.1709768  0.391
2019 Shao Q, Yang M, Liang C, Ma L, Zhang W, Jiang Z, Luo J, Lee JK, Liang C, Chen JF. and mutant mice reveal MTORC1 activation due to impaired lysosomal degradation and exocytosis. Autophagy. PMID 31847700 DOI: 10.1080/15548627.2019.1703353  0.344
2019 Quach C, Song Y, Guo H, Li S, Maazi H, Fung M, Sands N, O'Connell D, Restrepo-Vassalli S, Chai B, Nemecio D, Punj V, Akbari O, Idos GE, Mumenthaler SM, ... ... Liang C, et al. A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice. Nature Communications. 10: 5681. PMID 31831743 DOI: 10.1038/S41467-019-13475-W  0.351
2019 Tang X, Chang C, Guo J, Lincoln V, Liang C, Chen M, Woodley DT, Li W. Tumour-Secreted Hsp90α on External Surface of Exosomes Mediates Tumour - Stromal Cell Communication via Autocrine and Paracrine Mechanisms. Scientific Reports. 9: 15108. PMID 31641193 DOI: 10.1038/S41598-019-51704-W  0.309
2019 Li S, Song Y, Quach C, Nemecio D, Liang C. Revisiting the role of autophagy in melanoma. Autophagy. PMID 31242070 DOI: 10.1080/15548627.2019.1635386  0.382
2019 Li S, Song Y, Quach C, Guo H, Jang GB, Maazi H, Zhao S, Sands NA, Liu Q, In GK, Peng D, Yuan W, Machida K, Yu M, Akbari O, ... ... Liang C, et al. Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance. Nature Communications. 10: 1693. PMID 30979895 DOI: 10.1038/S41467-019-09634-8  0.341
2018 Li S, Jang GB, Quach C, Liang C. Darkening with UVRAG. Autophagy. PMID 30209981 DOI: 10.1080/15548627.2018.1522911  0.343
2018 Yang Y, Jang GB, Yang X, Wang Q, He S, Li S, Quach C, Zhao S, Li F, Yuan Z, Lee HR, Zhong H, Liang C. Central role of autophagic UVRAG in melanogenesis and the suntan response. Proceedings of the National Academy of Sciences of the United States of America. PMID 30061422 DOI: 10.1073/Pnas.1803303115  0.372
2018 Machida K, Siddique HR, Zheng M, Winer P, Kumar DBU, Rokan A, Sher L, Tahara SM, Elowitz M, Liang C, Tsukamoto H. Abstract 1984: Cell fate reprogramming of liver tumor-initiating stem-like cells via phosphorylated NUMB and TBC1D15 Cancer Research. 78: 1984-1984. DOI: 10.1158/1538-7445.Am2018-1984  0.336
2017 Liang Q, Wei D, Chung B, Brulois KF, Guo C, Dong S, Gao SJ, Feng P, Liang C, Jung JU. A novel role of vBcl2 in the virion assembly of Kaposi's sarcoma-associated herpesvirus. Journal of Virology. PMID 29167347 DOI: 10.1128/Jvi.00914-17  0.412
2017 Sparrer KMJ, Gableske S, Zurenski MA, Parker ZM, Full F, Baumgart GJ, Kato J, Pacheco-Rodriguez G, Liang C, Pornillos O, Moss J, Vaughan M, Gack MU. TRIM23 mediates virus-induced autophagy via activation of TBK1. Nature Microbiology. PMID 28871090 DOI: 10.1038/S41564-017-0017-2  0.409
2017 Guo J, Jayaprakash P, Dan J, Wise P, Jang GB, Liang C, Chen M, Woodley DT, Fabbri M, Li W. PRAS40 Connects Microenvironmental Stress Signaling to Exosome-Mediated Secretion. Molecular and Cellular Biology. PMID 28674187 DOI: 10.1128/Mcb.00171-17  0.354
2017 Cheng J, Liao Y, Xiao L, Wu R, Zhao S, Chen H, Hou B, Zhang X, Liang C, Xu Y, Yuan Z. Autophagy regulates MAVS signaling activation in a phosphorylation-dependent manner in microglia. Cell Death and Differentiation. 24: 276-287. PMID 28141795 DOI: 10.1038/Cdd.2016.121  0.344
2016 Yang Y, Quach C, Liang C. Autophagy Modulator Takes A Part in UV Protection. Autophagy. 0. PMID 27439570 DOI: 10.1080/15548627.2016.1196319  0.345
2016 Yang Y, He S, Wang Q, Li F, Kwak MJ, Chen S, O'Connell D, Zhang T, Pirooz SD, Jeon Y, Chimge NO, Frenkel B, Choi Y, Aldrovandi GM, Oh BH, ... ... Liang C, et al. Autophagic UVRAG Promotes UV-Induced Photolesion Repair by Activation of the CRL4(DDB2) E3 Ligase. Molecular Cell. 62: 507-519. PMID 27203177 DOI: 10.1016/J.Molcel.2016.04.014  0.326
2016 O'Connell D, Liang C. Autophagy interaction with herpes simplex virus type-1 infection. Autophagy. 1-9. PMID 26934628 DOI: 10.1080/15548627.2016.1139262  0.33
2016 Chimge NO, Little GH, Baniwal SK, Adisetiyo H, Xie Y, Zhang T, O'Laughlin A, Liu ZY, Ulrich P, Martin A, Mhawech-Fauceglia P, Ellis MJ, Tripathy D, Groshen S, Liang C, et al. RUNX1 prevents oestrogen-mediated AXIN1 suppression and β-catenin activation in ER-positive breast cancer. Nature Communications. 7: 10751. PMID 26916619 DOI: 10.1038/Ncomms10751  0.315
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... Liang C, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.347
2015 Yang Y, Liang C. MicroRNAs: an emerging player in autophagy. Scienceopen Research. 2015. PMID 26744638 DOI: 10.14293/S2199-1006.1.Sor-Life.A181Cu.V1  0.307
2015 Mi Z, Ding J, Zhang Q, Zhao J, Ma L, Yu H, Liu Z, Shan G, Li X, Zhou J, Wei T, Zhang L, Guo F, Liang C, Cen S. A small molecule compound IMB-LA inhibits HIV-1 infection by preventing viral Vpu from antagonizing the host restriction factor BST-2. Scientific Reports. 5: 18499. PMID 26669976 DOI: 10.1038/srep18499  0.309
2015 He S, Liang C. Frameshift mutation of UVRAG: Switching a tumor suppressor to an oncogene in colorectal cancer. Autophagy. 0. PMID 26327192 DOI: 10.1080/15548627.2015.1086523  0.305
2015 He S, Zhao Z, Yang Y, O'Connell D, Zhang X, Oh S, Ma B, Lee JH, Zhang T, Varghese B, Yip J, Dolatshahi Pirooz S, Li M, Zhang Y, Li GM, ... ... Liang C, et al. Truncating mutation in the autophagy gene UVRAG confers oncogenic properties and chemosensitivity in colorectal cancers. Nature Communications. 6: 7839. PMID 26234763 DOI: 10.1038/Ncomms8839  0.343
2015 Minassian A, Zhang J, He S, Zhao J, Zandi E, Saito T, Liang C, Feng P. An Internally Translated MAVS Variant Exposes Its Amino-terminal TRAF-Binding Motifs to Deregulate Interferon Induction. Plos Pathogens. 11: e1005060. PMID 26221961 DOI: 10.1371/Journal.Ppat.1005060  0.365
2015 He S, Zhao J, Song S, He X, Minassian A, Zhou Y, Zhang J, Brulois K, Wang Y, Cabo J, Zandi E, Liang C, Jung JU, Zhang X, Feng P. Viral pseudo-enzymes activate RIG-I via deamidation to evade cytokine production. Molecular Cell. 58: 134-46. PMID 25752576 DOI: 10.1016/J.Molcel.2015.01.036  0.309
2015 Liang Q, Chang B, Lee P, Brulois KF, Ge J, Shi M, Rodgers MA, Feng P, Oh BH, Liang C, Jung JU. Identification of the Essential Role of Viral Bcl-2 for Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication. Journal of Virology. 89: 5308-17. PMID 25740994 DOI: 10.1128/Jvi.00102-15  0.357
2015 Liang C, Oh BH, Jung JU. Novel functions of viral anti-apoptotic factors. Nature Reviews. Microbiology. 13: 7-12. PMID 25363821 DOI: 10.1038/Nrmicro3369  0.394
2014 Pirooz S, He S, O'Connell D, Khalilzadeh P, Yang Y, Liang C. Viruses customize autophagy protein for efficient viral entry. Autophagy. 10: 1355-6. PMID 24905575 DOI: 10.4172/2161-0517.S1.006  0.361
2014 Pirooz SD, He S, Zhang T, Zhang X, Zhao Z, Oh S, O'Connell D, Khalilzadeh P, Amini-Bavil-Olyaee S, Farzan M, Liang C. UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs. Proceedings of the National Academy of Sciences of the United States of America. 111: 2716-21. PMID 24550300 DOI: 10.1073/Pnas.1320629111  0.357
2014 Coleman CB, McGraw JE, Feldman ER, Roth AN, Keyes LR, Grau KR, Cochran SL, Waldschmidt TJ, Liang C, Forrest JC, Tibbetts SA. A gammaherpesvirus Bcl-2 ortholog blocks B cell receptor-mediated apoptosis and promotes the survival of developing B cells in vivo. Plos Pathogens. 10: e1003916. PMID 24516386 DOI: 10.1371/Journal.Ppat.1003916  0.317
2014 He S, O'Connell D, Zhang X, Yang Y, Liang C. The intersection of Golgi-ER retrograde and autophagic trafficking. Autophagy. 10: 180-1. PMID 24246972 DOI: 10.4161/Auto.26917  0.325
2013 He S, Ni D, Ma B, Lee JH, Zhang T, Ghozalli I, Pirooz SD, Zhao Z, Bharatham N, Li B, Oh S, Lee WH, Takahashi Y, Wang HG, Minassian A, ... ... Liang C, et al. PtdIns(3)P-bound UVRAG coordinates Golgi-ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex. Nature Cell Biology. 15: 1206-19. PMID 24056303 DOI: 10.1038/Ncb2848  0.325
2013 Trisciuoglio D, De Luca T, Desideri M, Passeri D, Gabellini C, Scarpino S, Liang C, Orlandi A, Del Bufalo D. Removal of the BH4 domain from Bcl-2 protein triggers an autophagic process that impairs tumor growth. Neoplasia (New York, N.Y.). 15: 315-27. PMID 23479509 DOI: 10.1593/Neo.121392  0.338
2012 Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Liang C, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496  0.309
2012 Zhao Z, Ni D, Ghozalli I, Pirooz SD, Ma B, Liang C. UVRAG: at the crossroad of autophagy and genomic stability. Autophagy. 8: 1392-3. PMID 22885520 DOI: 10.4161/Auto.21035  0.334
2012 Kim HJ, Zhong Q, Sheng ZH, Yoshimori T, Liang C, Jung JU. Beclin-1-interacting autophagy protein Atg14L targets the SNARE-associated protein Snapin to coordinate endocytic trafficking. Journal of Cell Science. 125: 4740-50. PMID 22797916 DOI: 10.1242/Jcs.100339  0.385
2012 Zhao Z, Oh S, Li D, Ni D, Pirooz SD, Lee JH, Yang S, Lee JY, Ghozalli I, Costanzo V, Stark JM, Liang C. A dual role for UVRAG in maintaining chromosomal stability independent of autophagy. Developmental Cell. 22: 1001-16. PMID 22542840 DOI: 10.1016/J.Devcel.2011.12.027  0.333
2012 Yang CS, Lee JS, Rodgers M, Min CK, Lee JY, Kim HJ, Lee KH, Kim CJ, Oh B, Zandi E, Yue Z, Kramnik I, Liang C, Jung JU. Autophagy protein Rubicon mediates phagocytic NADPH oxidase activation in response to microbial infection or TLR stimulation. Cell Host & Microbe. 11: 264-76. PMID 22423966 DOI: 10.1016/J.Chom.2012.01.018  0.352
2012 Liang C. Viral FLIPping autophagy for longevity. Cell Host & Microbe. 11: 101-3. PMID 22341458 DOI: 10.1016/J.Chom.2012.01.012  0.342
2011 Lee G, Liang C, Park G, Jang C, Jung JU, Chung J. UVRAG is required for organ rotation by regulating Notch endocytosis in Drosophila. Developmental Biology. 356: 588-97. PMID 21729695 DOI: 10.1016/J.Ydbio.2011.06.024  0.321
2011 Oh S, Pirooz SD, Ni D, Zhao Z, Liang C. Anti-autophagic Bcl-2: Not just an innocent bystander. Autophagy. 7: 231-2. PMID 21099349 DOI: 10.4161/Auto.7.2.14198  0.365
2011 Ku B, Liang C, Jung JU, Oh BH. Evidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAX. Cell Research. 21: 627-41. PMID 21060336 DOI: 10.1038/Cr.2010.149  0.329
2011 Oh S, Xiaofei E, Ni D, Pirooz SD, Lee JY, Lee D, Zhao Z, Lee S, Lee H, Ku B, Kowalik T, Martin SE, Oh BH, Jung JU, Liang C. Downregulation of autophagy by Bcl-2 promotes MCF7 breast cancer cell growth independent of its inhibition of apoptosis. Cell Death and Differentiation. 18: 452-64. PMID 20885445 DOI: 10.1038/Cdd.2010.116  0.369
2011 Liang C. Herpesviral Interaction with Autophagy Journal of Bacteriology and Virology. 41: 213-223. DOI: 10.4167/Jbv.2011.41.4.213  0.41
2010 Liang C. Negative regulation of autophagy Cell Death and Differentiation. 17: 1807-1815. PMID 20865012 DOI: 10.1038/Cdd.2010.115  0.361
2010 Liang C, Jung JU. Autophagy genes as tumor suppressors. Current Opinion in Cell Biology. 22: 226-33. PMID 19945837 DOI: 10.1016/J.Ceb.2009.11.003  0.345
2010 Oh S, E X, Hwang S, Liang C. Autophagy evasion in herpesviral latency. Autophagy. 6: 151-2. PMID 19923915 DOI: 10.4161/Auto.6.1.10536  0.429
2009 Lee JS, Li Q, Lee JY, Lee SH, Jeong JH, Lee HR, Chang H, Zhou FC, Gao SJ, Liang C, Jung JU. FLIP-mediated autophagy regulation in cell death control. Nature Cell Biology. 11: 1355-62. PMID 19838173 DOI: 10.1038/Ncb1980  0.346
2009 E X, Hwang S, Oh S, Lee JS, Jeong JH, Gwack Y, Kowalik TF, Sun R, Jung JU, Liang C. Viral Bcl-2-mediated evasion of autophagy aids chronic infection of gammaherpesvirus 68. Plos Pathogens. 5: e1000609. PMID 19816569 DOI: 10.1371/Journal.Ppat.1000609  0.394
2009 Lee HR, Kim MH, Lee JS, Liang C, Jung JU. Viral interferon regulatory factors. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 29: 621-7. PMID 19715458 DOI: 10.1089/Jir.2009.0067  0.358
2008 Gack MU, Kirchhofer A, Shin YC, Inn KS, Liang C, Cui S, Myong S, Ha T, Hopfner KP, Jung JU. Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 105: 16743-8. PMID 18948594 DOI: 10.1073/Pnas.0804947105  0.39
2008 Liang C, Lee JS, Jung JU. Immune evasion in Kaposi's sarcoma-associated herpes virus associated oncogenesis. Seminars in Cancer Biology. 18: 423-36. PMID 18948197 DOI: 10.1016/J.Semcancer.2008.09.003  0.305
2008 Sir D, Liang C, Chen WL, Jung JU, Ou JH. Perturbation of autophagic pathway by hepatitis C virus. Autophagy. 4: 830-1. PMID 18635950 DOI: 10.4161/Auto.6566  0.305
2008 Liang C, Sir D, Lee S, Ou JH, Jung JU. Beyond autophagy: the role of UVRAG in membrane trafficking. Autophagy. 4: 817-20. PMID 18612260 DOI: 10.4161/Auto.6496  0.37
2008 Liang C, Lee JS, Inn KS, Gack MU, Li Q, Roberts EA, Vergne I, Deretic V, Feng P, Akazawa C, Jung JU. Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking. Nature Cell Biology. 10: 776-87. PMID 18552835 DOI: 10.1038/Ncb1740  0.341
2008 Ku B, Woo JS, Liang C, Lee KH, Jung JU, Oh BH. An insight into the mechanistic role of Beclin 1 and its inhibition by prosurvival Bcl-2 family proteins. Autophagy. 4: 519-20. PMID 18334862 DOI: 10.4161/Auto.5846  0.32
2008 Ku B, Woo JS, Liang C, Lee KH, Hong HS, E X, Kim KS, Jung JU, Oh BH. Structural and biochemical bases for the inhibition of autophagy and apoptosis by viral BCL-2 of murine gamma-herpesvirus 68. Plos Pathogens. 4: e25. PMID 18248095 DOI: 10.1371/Journal.Ppat.0040025  0.36
2008 Liang C, E X, Jung JU. Downregulation of autophagy by herpesvirus Bcl-2 homologs. Autophagy. 4: 268-72. PMID 17993780 DOI: 10.4161/Auto.5210  0.423
2007 Feng P, Liang C, Shin YC, Xiaofei E, Zhang W, Gravel R, Wu TT, Sun R, Usherwood E, Jung JU. A novel inhibitory mechanism of mitochondrion-dependent apoptosis by a herpesviral protein. Plos Pathogens. 3: e174. PMID 18069888 DOI: 10.1371/Journal.Ppat.0030174  0.39
2007 Takahashi Y, Coppola D, Matsushita N, Cualing HD, Sun M, Sato Y, Liang C, Jung JU, Cheng JQ, Mulé JJ, Pledger WJ, Wang HG. Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis. Nature Cell Biology. 9: 1142-51. PMID 17891140 DOI: 10.1038/Ncb1634  0.395
2007 Gack MU, Shin YC, Joo CH, Urano T, Liang C, Sun L, Takeuchi O, Akira S, Chen Z, Inoue S, Jung JU. TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity. Nature. 446: 916-920. PMID 17392790 DOI: 10.1038/Nature05732  0.382
2007 Liang C, Feng P, Ku B, Oh BH, Jung JU. UVRAG: a new player in autophagy and tumor cell growth. Autophagy. 3: 69-71. PMID 17106237 DOI: 10.4161/Auto.3437  0.408
2006 Liang C, Feng P, Ku B, Dotan I, Canaani D, Oh BH, Jung JU. Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG. Nature Cell Biology. 8: 688-99. PMID 16799551 DOI: 10.1038/Ncb1426  0.386
2005 Liang C, Rieder E, Hahm B, Jang SK, Paul A, Wimmer E. Replication of a novel subgenomic HCV genotype 1a replicon expressing a puromycin resistance gene in Huh-7 cells. Virology. 333: 41-53. PMID 15708591 DOI: 10.1016/J.Virol.2004.12.031  0.461
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