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Lili Wan, Ph.D. - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Spinal Muscular Atrophy, RNA binding proteins, Splicing, High-Throughput Screening
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29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Oh JM, Venters CC, Di C, Pinto AM, Wan L, Younis I, Cai Z, Arai C, So BR, Duan J, Dreyfuss G. U1 snRNP regulates cancer cell migration and invasion in vitro. Nature Communications. 11: 1. PMID 31911652 DOI: 10.1038/S41467-019-13993-7  0.56
2018 Li D, Zhang J, Wang M, Li X, Gong H, Tang H, Chen L, Wan L, Liu Q. Activity dependent LoNA regulates translation by coordinating rRNA transcription and methylation. Nature Communications. 9: 1726. PMID 29712923 DOI: 10.1038/S41467-018-04072-4  0.33
2017 Oh JM, Di C, Venters CC, Guo J, Arai C, So BR, Pinto AM, Zhang Z, Wan L, Younis I, Dreyfuss G. U1 snRNP telescripting regulates a size-function-stratified human genome. Nature Structural & Molecular Biology. PMID 28967884 DOI: 10.1038/Nsmb.3473  0.528
2017 Wan L, Dreyfuss G. Splicing-Correcting Therapy for SMA. Cell. 170: 5. PMID 28666123 DOI: 10.1016/J.Cell.2017.06.028  0.606
2016 So BR, Wan L, Zhang Z, Li P, Babiash E, Duan J, Younis I, Dreyfuss G. A U1 snRNP-specific assembly pathway reveals the SMN complex as a versatile hub for RNP exchange. Nature Structural & Molecular Biology. PMID 26828962 DOI: 10.1038/Nsmb.3167  0.637
2013 Zhang Z, Pinto AM, Wan L, Wang W, Berg MG, Oliva I, Singh LN, Dengler C, Wei Z, Dreyfuss G. Dysregulation of synaptogenesis genes antecedes motor neuron pathology in spinal muscular atrophy. Proceedings of the National Academy of Sciences of the United States of America. 110: 19348-53. PMID 24191055 DOI: 10.1073/Pnas.1319280110  0.611
2013 Younis I, Dittmar K, Wang W, Foley SW, Berg MG, Hu KY, Wei Z, Wan L, Dreyfuss G. Minor introns are embedded molecular switches regulated by highly unstable U6atac snRNA. Elife. 2: e00780. PMID 23908766 DOI: 10.7554/Elife.00780  0.556
2013 Younis I, Dittmar K, Wang W, Foley SW, Berg MG, Hu KY, Wei Z, Wan L, Dreyfuss G. Author response: Minor introns are embedded molecular switches regulated by highly unstable U6atac snRNA Elife. DOI: 10.7554/Elife.00780.017  0.46
2012 Berg MG, Singh LN, Younis I, Liu Q, Pinto AM, Kaida D, Zhang Z, Cho S, Sherrill-Mix S, Wan L, Dreyfuss G. U1 snRNP determines mRNA length and regulates isoform expression. Cell. 150: 53-64. PMID 22770214 DOI: 10.1016/J.Cell.2012.05.029  0.57
2012 Berg MG, Wan L, Younis I, Diem MD, Soo M, Wang C, Dreyfuss G. A quantitative high-throughput in vitro splicing assay identifies inhibitors of spliceosome catalysis. Molecular and Cellular Biology. 32: 1271-83. PMID 22252314 DOI: 10.1128/Mcb.05788-11  0.748
2011 Zhang R, So BR, Li P, Yong J, Glisovic T, Wan L, Dreyfuss G. Structure of a key intermediate of the SMN complex reveals Gemin2's crucial function in snRNP assembly. Cell. 146: 384-95. PMID 21816274 DOI: 10.1016/J.Cell.2011.06.043  0.741
2010 Kaida D, Berg MG, Younis I, Kasim M, Singh LN, Wan L, Dreyfuss G. U1 snRNP protects pre-mRNAs from premature cleavage and polyadenylation. Nature. 468: 664-8. PMID 20881964 DOI: 10.1038/Nature09479  0.554
2010 Yong J, Kasim M, Bachorik JL, Wan L, Dreyfuss G. Gemin5 delivers snRNA precursors to the SMN complex for snRNP biogenesis. Molecular Cell. 38: 551-62. PMID 20513430 DOI: 10.1016/J.Molcel.2010.03.014  0.734
2009 Cooper TA, Wan L, Dreyfuss G. RNA and disease. Cell. 136: 777-93. PMID 19239895 DOI: 10.1016/J.Cell.2009.02.011  0.614
2008 Wan L, Ottinger E, Cho S, Dreyfuss G. Inactivation of the SMN complex by oxidative stress. Molecular Cell. 31: 244-54. PMID 18657506 DOI: 10.1016/J.Molcel.2008.06.004  0.598
2008 Zhang Z, Lotti F, Dittmar K, Younis I, Wan L, Kasim M, Dreyfuss G. SMN deficiency causes tissue-specific perturbations in the repertoire of snRNAs and widespread defects in splicing. Cell. 133: 585-600. PMID 18485868 DOI: 10.1016/J.Cell.2008.03.031  0.644
2006 Battle DJ, Kasim M, Yong J, Lotti F, Lau CK, Mouaikel J, Zhang Z, Han K, Wan L, Dreyfuss G. The SMN complex: an assembly machine for RNPs. Cold Spring Harbor Symposia On Quantitative Biology. 71: 313-20. PMID 17381311 DOI: 10.1101/Sqb.2006.71.001  0.785
2006 Battle DJ, Lau CK, Wan L, Deng H, Lotti F, Dreyfuss G. The Gemin5 protein of the SMN complex identifies snRNAs. Molecular Cell. 23: 273-9. PMID 16857593 DOI: 10.1016/J.Molcel.2006.05.036  0.804
2005 Wan L, Battle DJ, Yong J, Gubitz AK, Kolb SJ, Wang J, Dreyfuss G. The survival of motor neurons protein determines the capacity for snRNP assembly: biochemical deficiency in spinal muscular atrophy. Molecular and Cellular Biology. 25: 5543-51. PMID 15964810 DOI: 10.1128/Mcb.25.13.5543-5551.2005  0.761
2005 Feng W, Gubitz AK, Wan L, Battle DJ, Dostie J, Golembe TJ, Dreyfuss G. Gemins modulate the expression and activity of the SMN complex. Human Molecular Genetics. 14: 1605-11. PMID 15843395 DOI: 10.1093/Hmg/Ddi168  0.787
2005 Golembe TJ, Yong J, Battle DJ, Feng W, Wan L, Dreyfuss G. Lymphotropic Herpesvirus saimiri uses the SMN complex to assemble Sm cores on its small RNAs. Molecular and Cellular Biology. 25: 602-11. PMID 15632062 DOI: 10.1128/Mcb.25.2.602-611.2005  0.778
2004 Yong J, Wan L, Dreyfuss G. Why do cells need an assembly machine for RNA-protein complexes? Trends in Cell Biology. 14: 226-32. PMID 15130578 DOI: 10.1016/J.Tcb.2004.03.010  0.749
2001 Wan L, Kim JK, Pollard VW, Dreyfuss G. Mutational definition of RNA-binding and protein-protein interaction domains of heterogeneous nuclear RNP C1. The Journal of Biological Chemistry. 276: 7681-8. PMID 11113151 DOI: 10.1074/Jbc.M010207200  0.576
2000 Wan L, Dockendorff TC, Jongens TA, Dreyfuss G. Characterization of dFMR1, a Drosophila melanogaster homolog of the fragile X mental retardation protein. Molecular and Cellular Biology. 20: 8536-47. PMID 11046149 DOI: 10.1128/Mcb.20.22.8536-8547.2000  0.593
1999 Kamma H, Horiguchi H, Wan L, Matsui M, Fujiwara M, Fujimoto M, Yazawa T, Dreyfuss G. Molecular characterization of the hnRNP A2/B1 proteins: tissue-specific expression and novel isoforms. Experimental Cell Research. 246: 399-411. PMID 9925756 DOI: 10.1006/Excr.1998.4323  0.5
1999 Nakielny S, Kataoka N, Siomi H, Wan L, Siomi M, Dreyfuss G. Ran-regulated interactions of nuclear import and export receptors with nucleoporins Biochemistry and Cell Biology. 77: 403. DOI: 10.1139/O99-903Y  0.471
1998 Siomi MC, Fromont M, Rain JC, Wan L, Wang F, Legrain P, Dreyfuss G. Functional conservation of the transportin nuclear import pathway in divergent organisms. Molecular and Cellular Biology. 18: 4141-8. PMID 9632798 DOI: 10.1128/Mcb.18.7.4141  0.573
1997 Siomi MC, Eder PS, Kataoka N, Wan L, Liu Q, Dreyfuss G. Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins. The Journal of Cell Biology. 138: 1181-92. PMID 9298975 DOI: 10.1083/Jcb.138.6.1181  0.569
1996 Liu Q, Siomi H, Siomi MC, Fischer U, Zhang Y, Wan L, Dreyfuss G. Molecular characterization of the protein products of the fragile X syndrome gene and the survival of motor neurons gene. Cold Spring Harbor Symposia On Quantitative Biology. 61: 689-97. PMID 9246495 DOI: 10.1101/Sqb.1996.061.01.069  0.53
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