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Peng Yuan, Ph.D - Publications

Affiliations: 
2011-2016 Neurology Yale University, New Haven, CT 
 2016- Biology Stanford University, Palo Alto, CA 
Area:
Alzheimer's disease, microscopy
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27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Cheng X, Zhao R, Qiu H, Song P, Kou L, Sang S, Xia Y, Cai W, Jin B, Huang Q, Yuan P, Zhong C. The mechanism and consequences of amyloid-β modulating thiamine pyrophosphokinase-1 expression in microglia. Biorxiv : the Preprint Server For Biology. PMID 39345559 DOI: 10.1101/2024.09.18.613405  0.303
2023 Tong L, Han S, Xue Y, Chen M, Chen F, Ke W, Shu Y, Ding N, Bewersdorf J, Zhou ZJ, Yuan P, Grutzendler J. Single cell optogenetic stimulation by two-photon excitation fluorescence transfer. Iscience. 26: 107857. PMID 37752954 DOI: 10.1016/j.isci.2023.107857  0.748
2023 Yang H, Yuan P, Wu Y, Shi M, Caro CD, Tengeiji A, Yamanoi S, Inoue M, DeGrado WF, Condello C. EMBER multidimensional spectral microscopy enables quantitative determination of disease- and cell-specific amyloid strains. Proceedings of the National Academy of Sciences of the United States of America. 120: e2300769120. PMID 36927157 DOI: 10.1073/pnas.2300769120  0.686
2023 Yang H, Yuan P, Wu Y, Shi M, Caro CD, Tengeiji A, Yamanoi S, Inoue M, DeGrado WF, Condello C. EMBER multi-dimensional spectral microscopy enables quantitative determination of disease- and cell-specific amyloid strains. Biorxiv : the Preprint Server For Biology. PMID 36778268 DOI: 10.1101/2023.02.01.526692  0.682
2023 Johnson NR, Yuan P, Castillo E, Lopez TP, Yue W, Bond A, Rivera BM, Sullivan MC, Hirouchi M, Giles K, Aoyagi A, Condello C. CSF1R inhibitors induce a sex-specific resilient microglial phenotype and functional rescue in a tauopathy mouse model. Nature Communications. 14: 118. PMID 36624100 DOI: 10.1038/s41467-022-35753-w  0.627
2022 Yuan P, Zhang M, Tong L, Morse TM, McDougal RA, Ding H, Chan D, Cai Y, Grutzendler J. PLD3 affects axonal spheroids and network defects in Alzheimer's disease. Nature. PMID 36450991 DOI: 10.1038/s41586-022-05491-6  0.765
2021 Maxwell AM, Yuan P, Rivera BM, Schaaf W, Mladinov M, Prasher VP, Robinson AC, DeGrado WF, Condello C. Emergence of distinct and heterogeneous strains of amyloid beta with advanced Alzheimer's disease pathology in Down syndrome. Acta Neuropathologica Communications. 9: 201. PMID 34961556 DOI: 10.1186/s40478-021-01298-0  0.678
2021 Velasco MGM, Zhang M, Antonello J, Yuan P, Allgeyer ES, May D, M'Saad O, Kidd P, Barentine AES, Greco V, Grutzendler J, Booth MJ, Bewersdorf J. 3D super-resolution deep-tissue imaging in living mice. Optica. 8: 442-450. PMID 34239948 DOI: 10.1364/OPTICA.416841  0.706
2020 Tong L, Hill RA, Damisah EC, Murray KN, Yuan P, Bordey A, Grutzendler J. Imaging and optogenetic modulation of vascular mural cells in the live brain. Nature Protocols. PMID 33299155 DOI: 10.1038/s41596-020-00425-w  0.763
2020 Yao S, Yuan P, Ouellette B, Zhou T, Mortrud M, Balaram P, Chatterjee S, Wang Y, Daigle TL, Tasic B, Kuang X, Gong H, Luo Q, Zeng S, Curtright A, et al. RecV recombinase system for in vivo targeted optogenomic modifications of single cells or cell populations. Nature Methods. PMID 32203389 DOI: 10.1038/S41592-020-0774-3  0.5
2017 Condello C, Yuan P, Grutzendler J. Microglia-Mediated Neuroprotection, TREM2, and Alzheimer's Disease: Evidence From Optical Imaging. Biological Psychiatry. PMID 29169609 DOI: 10.1016/J.Biopsych.2017.10.007  0.795
2017 Yang J, Zhang X, Yuan P, Yang J, Xu Y, Grutzendler J, Shao Y, Moore A, Ran C. Oxalate-curcumin-based probe for micro- and macroimaging of reactive oxygen species in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 29109280 DOI: 10.1073/Pnas.1706248114  0.714
2016 Yuan P, Condello C, Keene CD, Wang Y, Bird TD, Paul SM, Luo W, Colonna M, Baddeley D, Grutzendler J. TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy. Neuron. 92: 252-264. PMID 27710785 DOI: 10.1016/j.neuron.2016.09.016  0.752
2016 Yuan P, Condello C, Keene CD, Wang Y, Bird TD, Paul SM, Luo W, Colonna M, Baddeley D, Grutzendler J. TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy. Neuron. 90: 724-739. PMID 27196974 DOI: 10.1016/J.Neuron.2016.05.003  0.796
2016 Wang Y, Ulland TK, Ulrich JD, Song W, Tzaferis JA, Hole JT, Yuan P, Mahan TE, Shi Y, Gilfillan S, Cella M, Grutzendler J, DeMattos RB, Cirrito JR, Holtzman DM, et al. TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques. The Journal of Experimental Medicine. PMID 27091843 DOI: 10.1084/Jem.20151948  0.721
2016 Han L, Kong DK, Zheng M, Murikinati S, Ma C, Yuan P, Li L, Tian D, Cai Q, Ye C, Holden D, Park JH, Gao X, Thomas JL, Grutzendler J, et al. Increased Nanoparticle Delivery to Brain Tumors by Autocatalytic Priming for Improved Treatment and Imaging. Acs Nano. PMID 26967254 DOI: 10.1021/Acsnano.5B07573  0.626
2016 Yuan P, Grutzendler J. Attenuation of β-Amyloid Deposition and Neurotoxicity by Chemogenetic Modulation of Neural Activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 632-41. PMID 26758850 DOI: 10.1523/Jneurosci.2531-15.2016  0.707
2016 Wang Y, Ulland T, Ulrich JD, Song W, Yuan P, Mahan TE, Shi Y, Gilfillan S, Cella M, DeMattos RB, Grutzendler J, Cirrito JR, Holtzman DM, Colonna M. O2-07-02: Trem2-Mediated Early Response by Resident Microglia Limits Diffusion and Toxicity of Amyloid Plaques Alzheimer's & Dementia. 12: P241-P242. DOI: 10.1016/J.Jalz.2016.06.431  0.65
2016 Ran C, Yang J, Yang J, Yuan P, Grutzendler J, Xu Y. O1-12-04: Near Infrared Fluorescence Imaging of Reactive Oxygen Species in Alzheimer’s Disease Via Transformation From “Visible” to “Invisible” Alzheimer's & Dementia. 12: P206-P206. DOI: 10.1016/J.Jalz.2016.06.361  0.623
2015 Velasco MG, Allgeyer ES, Yuan P, Grutzendler J, Bewersdorf J. Absolute two-photon excitation spectra of red and far-red fluorescent probes. Optics Letters. 40: 4915-8. PMID 26512482 DOI: 10.1364/Ol.40.004915  0.617
2015 Gowrishankar S, Yuan P, Wu Y, Schrag M, Paradise S, Grutzendler J, De Camilli P, Ferguson SM. Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer's disease amyloid plaques. Proceedings of the National Academy of Sciences of the United States of America. PMID 26124111 DOI: 10.1073/Pnas.1510329112  0.719
2015 Hill RA, Tong L, Yuan P, Murikinati S, Gupta S, Grutzendler J. Regional Blood Flow in the Normal and Ischemic Brain Is Controlled by Arteriolar Smooth Muscle Cell Contractility and Not by Capillary Pericytes. Neuron. PMID 26119027 DOI: 10.1016/J.Neuron.2015.06.001  0.722
2015 Condello C, Yuan P, Schain A, Grutzendler J. Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques. Nature Communications. 6: 6176. PMID 25630253 DOI: 10.1038/Ncomms7176  0.769
2014 Zhang X, Tian Y, Yuan P, Li Y, Yaseen MA, Grutzendler J, Moore A, Ran C. A bifunctional curcumin analogue for two-photon imaging and inhibiting crosslinking of amyloid beta in Alzheimer's disease. Chemical Communications (Cambridge, England). 50: 11550-3. PMID 25134928 DOI: 10.1039/C4Cc03731F  0.727
2014 Grutzendler J, Murikinati S, Hiner B, Ji L, Lam CK, Yoo T, Gupta S, Hafler BP, Adelman RA, Yuan P, Rodriguez G. Angiophagy prevents early embolus washout but recanalizes microvessels through embolus extravasation. Science Translational Medicine. 6: 226ra31. PMID 24598589 DOI: 10.1126/Scitranslmed.3006585  0.634
2013 Condello C, Yuan P, Das P, Grutzendler J. P2-018: Microglia constitute a barrier that prevents the formation of neurotoxic oligomeric beta-amyloid hot spots around plaques Alzheimer's & Dementia. 9: P351-P351. DOI: 10.1016/J.Jalz.2013.05.660  0.767
2013 Yuan P, Condello C, Schain A, Grutzendler J. P1-033: A time stamp imaging method for measuring the kinetics and toxicity of beta-amyloid and tau deposition by sequential multicolor labeling with beta-sheet binding dyes Alzheimer's & Dementia. 9: P164-P164. DOI: 10.1016/J.Jalz.2013.05.253  0.738
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