Year |
Citation |
Score |
2024 |
Min W, Qin L, Zhang H, López-Giráldez F, Jiang N, Kim Y, Mohan VK, Su M, Murray KN, Grutzendler J, Zhou JH. mTORC1 Signaling in Brain Endothelial Progenitors Contributes to CCM Pathogenesis. Circulation Research. PMID 38957991 DOI: 10.1161/CIRCRESAHA.123.324015 |
0.618 |
|
2023 |
Tong L, Han S, Xue Y, Chen M, Chen F, Ke W, Shu Y, Ding N, Bewersdorf J, Zhou ZJ, Yuan P, Grutzendler J. Single cell optogenetic stimulation by two-photon excitation fluorescence transfer. Iscience. 26: 107857. PMID 37752954 DOI: 10.1016/j.isci.2023.107857 |
0.739 |
|
2023 |
Damisah EC, Rai A, Hill RA, Tong L, Grutzendler J. TREM2 and APOE do not modulate phagocytic clearance of dying cells in the live mammalian brain. Biorxiv : the Preprint Server For Biology. PMID 36993245 DOI: 10.1101/2023.03.17.533222 |
0.657 |
|
2022 |
Yuan P, Zhang M, Tong L, Morse TM, McDougal RA, Ding H, Chan D, Cai Y, Grutzendler J. PLD3 affects axonal spheroids and network defects in Alzheimer's disease. Nature. PMID 36450991 DOI: 10.1038/s41586-022-05491-6 |
0.723 |
|
2022 |
Aber ER, Griffey CJ, Davies T, Li AM, Yang YJ, Croce KR, Goldman JE, Grutzendler J, Canman JC, Yamamoto A. Oligodendroglial macroautophagy is essential for myelin sheath turnover to prevent neurodegeneration and death. Cell Reports. 41: 111480. PMID 36261002 DOI: 10.1016/j.celrep.2022.111480 |
0.651 |
|
2022 |
Ando K, Tong L, Peng D, Vázquez-Liébanas E, Chiyoda H, He L, Liu J, Kawakami K, Mochizuki N, Fukuhara S, Grutzendler J, Betsholtz C. KCNJ8/ABCC9-containing K-ATP channel modulates brain vascular smooth muscle development and neurovascular coupling. Developmental Cell. PMID 35588738 DOI: 10.1016/j.devcel.2022.04.019 |
0.541 |
|
2021 |
Velasco MGM, Zhang M, Antonello J, Yuan P, Allgeyer ES, May D, M'Saad O, Kidd P, Barentine AES, Greco V, Grutzendler J, Booth MJ, Bewersdorf J. 3D super-resolution deep-tissue imaging in living mice. Optica. 8: 442-450. PMID 34239948 DOI: 10.1364/OPTICA.416841 |
0.673 |
|
2021 |
Li AM, Hill RA, Grutzendler J. Intravital Imaging of Neocortical Heterotopia Reveals Aberrant Axonal Pathfinding and Myelination around Ectopic Neurons. Cerebral Cortex (New York, N.Y. : 1991). PMID 33877363 DOI: 10.1093/cercor/bhab090 |
0.735 |
|
2021 |
Zhou HJ, Qin L, Jiang Q, Murray KN, Zhang H, Li B, Lin Q, Graham M, Liu X, Grutzendler J, Min W. Caveolae-mediated Tie2 signaling contributes to CCM pathogenesis in a brain endothelial cell-specific Pdcd10-deficient mouse model. Nature Communications. 12: 504. PMID 33495460 DOI: 10.1038/s41467-020-20774-0 |
0.639 |
|
2020 |
Tong L, Hill RA, Damisah EC, Murray KN, Yuan P, Bordey A, Grutzendler J. Imaging and optogenetic modulation of vascular mural cells in the live brain. Nature Protocols. PMID 33299155 DOI: 10.1038/s41596-020-00425-w |
0.789 |
|
2020 |
Damisah EC, Hill RA, Rai A, Chen F, Rothlin CV, Ghosh S, Grutzendler J. Astrocytes and microglia play orchestrated roles and respect phagocytic territories during neuronal corpse removal in vivo. Science Advances. 6: eaba3239. PMID 32637606 DOI: 10.1126/Sciadv.Aba3239 |
0.752 |
|
2020 |
Hirbec H, Déglon N, Foo LC, Goshen I, Grutzendler J, Hangen E, Kreisel T, Linck N, Muffat J, Regio S, Rion S, Escartin C. Emerging technologies to study glial cells. Glia. PMID 31958188 DOI: 10.1002/glia.23780 |
0.49 |
|
2019 |
Grutzendler J, Nedergaard M. Cellular Control of Brain Capillary Blood Flow: In Vivo Imaging Veritas. Trends in Neurosciences. PMID 31255380 DOI: 10.1016/j.tins.2019.05.009 |
0.454 |
|
2019 |
Hill RA, Grutzendler J. Uncovering the biology of myelin with optical imaging of the live brain. Glia. PMID 31033062 DOI: 10.1002/glia.23635 |
0.578 |
|
2018 |
Shahbazi A, Kinnison J, Vescovi R, Du M, Hill R, Joesch M, Takeno M, Zeng H, da Costa NM, Grutzendler J, Kasthuri N, Scheirer WJ. Publisher Correction: Flexible Learning-Free Segmentation and Reconstruction of Neural Volumes. Scientific Reports. 8: 17585. PMID 30498261 DOI: 10.1038/S41598-018-36220-7 |
0.458 |
|
2018 |
Shahbazi A, Kinnison J, Vescovi R, Du M, Hill R, Joesch M, Takeno M, Zeng H, da Costa NM, Grutzendler J, Kasthuri N, Scheirer WJ. Flexible Learning-Free Segmentation and Reconstruction of Neural Volumes. Scientific Reports. 8: 14247. PMID 30250218 DOI: 10.1038/S41598-018-32628-3 |
0.474 |
|
2018 |
Hill RA, Li AM, Grutzendler J. Lifelong cortical myelin plasticity and age-related degeneration in the live mammalian brain. Nature Neuroscience. PMID 29556031 DOI: 10.1038/S41593-018-0120-6 |
0.715 |
|
2018 |
Schain AJ, Melo-Carrillo A, Borsook D, Grutzendler J, Strassman AM, Burstein R. Activation of pial and dural macrophages and dendritic cells by CSD (67 chrs). Annals of Neurology. PMID 29394508 DOI: 10.1002/Ana.25169 |
0.746 |
|
2017 |
Condello C, Yuan P, Grutzendler J. Microglia-Mediated Neuroprotection, TREM2, and Alzheimer's Disease: Evidence From Optical Imaging. Biological Psychiatry. PMID 29169609 DOI: 10.1016/J.Biopsych.2017.10.007 |
0.739 |
|
2017 |
Yang J, Zhang X, Yuan P, Yang J, Xu Y, Grutzendler J, Shao Y, Moore A, Ran C. Oxalate-curcumin-based probe for micro- and macroimaging of reactive oxygen species in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 29109280 DOI: 10.1073/Pnas.1706248114 |
0.543 |
|
2017 |
Hill RA, Damisah EC, Chen F, Kwan AC, Grutzendler J. Targeted two-photon chemical apoptotic ablation of defined cell types in vivo. Nature Communications. 8: 15837. PMID 28621306 DOI: 10.1038/Ncomms15837 |
0.709 |
|
2017 |
Damisah EC, Hill RA, Tong L, Murray KN, Grutzendler J. A fluoro-Nissl dye identifies pericytes as distinct vascular mural cells during in vivo brain imaging. Nature Neuroscience. PMID 28504673 DOI: 10.1038/Nn.4564 |
0.775 |
|
2016 |
Yuan P, Condello C, Keene CD, Wang Y, Bird TD, Paul SM, Luo W, Colonna M, Baddeley D, Grutzendler J. TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy. Neuron. 92: 252-264. PMID 27710785 DOI: 10.1016/j.neuron.2016.09.016 |
0.694 |
|
2016 |
Yuan P, Condello C, Keene CD, Wang Y, Bird TD, Paul SM, Luo W, Colonna M, Baddeley D, Grutzendler J. TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy. Neuron. 90: 724-739. PMID 27196974 DOI: 10.1016/J.Neuron.2016.05.003 |
0.734 |
|
2016 |
Wang Y, Ulland TK, Ulrich JD, Song W, Tzaferis JA, Hole JT, Yuan P, Mahan TE, Shi Y, Gilfillan S, Cella M, Grutzendler J, DeMattos RB, Cirrito JR, Holtzman DM, et al. TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques. The Journal of Experimental Medicine. PMID 27091843 DOI: 10.1084/Jem.20151948 |
0.512 |
|
2016 |
Han L, Kong DK, Zheng M, Murikinati S, Ma C, Yuan P, Li L, Tian D, Cai Q, Ye C, Holden D, Park JH, Gao X, Thomas JL, Grutzendler J, et al. Increased Nanoparticle Delivery to Brain Tumors by Autocatalytic Priming for Improved Treatment and Imaging. Acs Nano. PMID 26967254 DOI: 10.1021/Acsnano.5B07573 |
0.459 |
|
2016 |
Akassoglou K, Agalliu D, Chang CJ, Davalos D, Grutzendler J, Hillman EM, Khakh BS, Kleinfeld D, McGavern DB, Nelson SJ, Zlokovic BV. Neurovascular and Immuno-Imaging: From Mechanisms to Therapies. Proceedings of the Inaugural Symposium. Frontiers in Neuroscience. 10: 46. PMID 26941593 DOI: 10.3389/Fnins.2016.00046 |
0.672 |
|
2016 |
Yuan P, Grutzendler J. Attenuation of β-Amyloid Deposition and Neurotoxicity by Chemogenetic Modulation of Neural Activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 632-41. PMID 26758850 DOI: 10.1523/Jneurosci.2531-15.2016 |
0.506 |
|
2016 |
Grutzendler J. Label-free Confocal Reflectance and 2-photon Microscopy of Myelinated Axons and Microvasculature in Live Mice Brain. DOI: 10.1364/Brain.2016.Bw4B.2 |
0.414 |
|
2016 |
Wang Y, Ulland T, Ulrich JD, Song W, Yuan P, Mahan TE, Shi Y, Gilfillan S, Cella M, DeMattos RB, Grutzendler J, Cirrito JR, Holtzman DM, Colonna M. O2-07-02: Trem2-Mediated Early Response by Resident Microglia Limits Diffusion and Toxicity of Amyloid Plaques Alzheimer's & Dementia. 12: P241-P242. DOI: 10.1016/J.Jalz.2016.06.431 |
0.422 |
|
2016 |
Ran C, Yang J, Yang J, Yuan P, Grutzendler J, Xu Y. O1-12-04: Near Infrared Fluorescence Imaging of Reactive Oxygen Species in Alzheimer’s Disease Via Transformation From “Visible” to “Invisible” Alzheimer's & Dementia. 12: P206-P206. DOI: 10.1016/J.Jalz.2016.06.361 |
0.412 |
|
2015 |
Velasco MG, Allgeyer ES, Yuan P, Grutzendler J, Bewersdorf J. Absolute two-photon excitation spectra of red and far-red fluorescent probes. Optics Letters. 40: 4915-8. PMID 26512482 DOI: 10.1364/Ol.40.004915 |
0.404 |
|
2015 |
Gowrishankar S, Yuan P, Wu Y, Schrag M, Paradise S, Grutzendler J, De Camilli P, Ferguson SM. Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer's disease amyloid plaques. Proceedings of the National Academy of Sciences of the United States of America. PMID 26124111 DOI: 10.1073/Pnas.1510329112 |
0.525 |
|
2015 |
Hill RA, Tong L, Yuan P, Murikinati S, Gupta S, Grutzendler J. Regional Blood Flow in the Normal and Ischemic Brain Is Controlled by Arteriolar Smooth Muscle Cell Contractility and Not by Capillary Pericytes. Neuron. PMID 26119027 DOI: 10.1016/J.Neuron.2015.06.001 |
0.678 |
|
2015 |
Condello C, Yuan P, Schain A, Grutzendler J. Microglia constitute a barrier that prevents neurotoxic protofibrillar Aβ42 hotspots around plaques. Nature Communications. 6: 6176. PMID 25630253 DOI: 10.1038/Ncomms7176 |
0.794 |
|
2014 |
Hill RA, Grutzendler J. In vivo imaging of oligodendrocytes with sulforhodamine 101. Nature Methods. 11: 1081-2. PMID 25357236 DOI: 10.1038/nmeth.3140 |
0.498 |
|
2014 |
Hill RA, Patel KD, Goncalves CM, Grutzendler J, Nishiyama A. Modulation of oligodendrocyte generation during a critical temporal window after NG2 cell division. Nature Neuroscience. 17: 1518-27. PMID 25262495 DOI: 10.1038/Nn.3815 |
0.643 |
|
2014 |
Zhang X, Tian Y, Yuan P, Li Y, Yaseen MA, Grutzendler J, Moore A, Ran C. A bifunctional curcumin analogue for two-photon imaging and inhibiting crosslinking of amyloid beta in Alzheimer's disease. Chemical Communications (Cambridge, England). 50: 11550-3. PMID 25134928 DOI: 10.1039/C4Cc03731F |
0.543 |
|
2014 |
Schain AJ, Hill RA, Grutzendler J. Label-free in vivo imaging of myelinated axons in health and disease with spectral confocal reflectance microscopy. Nature Medicine. 20: 443-9. PMID 24681598 DOI: 10.1038/nm.3495 |
0.774 |
|
2014 |
Grutzendler J, Murikinati S, Hiner B, Ji L, Lam CK, Yoo T, Gupta S, Hafler BP, Adelman RA, Yuan P, Rodriguez G. Angiophagy prevents early embolus washout but recanalizes microvessels through embolus extravasation. Science Translational Medicine. 6: 226ra31. PMID 24598589 DOI: 10.1126/Scitranslmed.3006585 |
0.691 |
|
2014 |
Whiteus C, Freitas C, Grutzendler J. Perturbed neural activity disrupts cerebral angiogenesis during a postnatal critical period. Nature. 505: 407-11. PMID 24305053 DOI: 10.1038/nature12821 |
0.776 |
|
2013 |
Grutzendler J. Angiophagy: mechanism of microvascular recanalization independent of the fibrinolytic system. Stroke; a Journal of Cerebral Circulation. 44: S84-6. PMID 23709741 DOI: 10.1161/STROKEAHA.112.678730 |
0.388 |
|
2013 |
Harb R, Whiteus C, Freitas C, Grutzendler J. In vivo imaging of cerebral microvascular plasticity from birth to death. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 146-56. PMID 23093067 DOI: 10.1038/Jcbfm.2012.152 |
0.773 |
|
2013 |
Condello C, Yuan P, Das P, Grutzendler J. P2-018: Microglia constitute a barrier that prevents the formation of neurotoxic oligomeric beta-amyloid hot spots around plaques Alzheimer's & Dementia. 9: P351-P351. DOI: 10.1016/J.Jalz.2013.05.660 |
0.69 |
|
2013 |
Yuan P, Condello C, Schain A, Grutzendler J. P1-033: A time stamp imaging method for measuring the kinetics and toxicity of beta-amyloid and tau deposition by sequential multicolor labeling with beta-sheet binding dyes Alzheimer's & Dementia. 9: P164-P164. DOI: 10.1016/J.Jalz.2013.05.253 |
0.761 |
|
2011 |
Condello C, Schain A, Grutzendler J. Multicolor time-stamp reveals the dynamics and toxicity of amyloid deposition. Scientific Reports. 1: 19. PMID 22355538 DOI: 10.1038/Srep00019 |
0.785 |
|
2011 |
Grutzendler J, Yang G, Pan F, Parkhurst CN, Gan WB. Transcranial two-photon imaging of the living mouse brain. Cold Spring Harbor Protocols. 2011. PMID 21880826 DOI: 10.1101/Pdb.Prot065474 |
0.807 |
|
2010 |
Liu Z, Condello C, Schain A, Harb R, Grutzendler J. CX3CR1 in microglia regulates brain amyloid deposition through selective protofibrillar amyloid-β phagocytosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 17091-101. PMID 21159979 DOI: 10.1523/Jneurosci.4403-10.2010 |
0.789 |
|
2010 |
Lam CK, Yoo T, Hiner B, Liu Z, Grutzendler J. Embolus extravasation is an alternative mechanism for cerebral microvascular recanalization. Nature. 465: 478-82. PMID 20505729 DOI: 10.1038/Nature09001 |
0.701 |
|
2010 |
Yang G, Pan F, Parkhurst CN, Grutzendler J, Gan WB. Thinned-skull cranial window technique for long-term imaging of the cortex in live mice. Nature Protocols. 5: 201-8. PMID 20134419 DOI: 10.1038/Nprot.2009.222 |
0.8 |
|
2009 |
Gan WB, Grutzendler J, Wong RO, Lichtman JW. Ballistic delivery of dyes for structural and functional studies of the nervous system. Cold Spring Harbor Protocols. 2009: pdb.prot5202. PMID 20147144 DOI: 10.1101/pdb.prot5202 |
0.767 |
|
2007 |
Grutzendler J, Gan WB. Long-term two-photon transcranial imaging of synaptic structures in the living brain. Csh Protocols. 2007: pdb.prot4766. PMID 21357119 DOI: 10.1101/Pdb.Prot4766 |
0.714 |
|
2007 |
Grutzendler J, Helmin K, Tsai J, Gan WB. Various dendritic abnormalities are associated with fibrillar amyloid deposits in Alzheimer's disease. Annals of the New York Academy of Sciences. 1097: 30-9. PMID 17413007 DOI: 10.1196/Annals.1379.003 |
0.701 |
|
2006 |
Grutzendler J, Gan WB. Two-photon imaging of synaptic plasticity and pathology in the living mouse brain. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 3: 489-96. PMID 17012063 DOI: 10.1016/J.Nurx.2006.07.005 |
0.723 |
|
2005 |
Davalos D, Grutzendler J, Yang G, Kim JV, Zuo Y, Jung S, Littman DR, Dustin ML, Gan WB. ATP mediates rapid microglial response to local brain injury in vivo. Nature Neuroscience. 8: 752-8. PMID 15895084 DOI: 10.1038/Nn1472 |
0.768 |
|
2004 |
Tsai J, Grutzendler J, Duff K, Gan WB. Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches. Nature Neuroscience. 7: 1181-3. PMID 15475950 DOI: 10.1038/Nn1335 |
0.701 |
|
2004 |
Coggan JS, Grutzendler J, Bishop DL, Cook MR, Gan W, Heym J, Lichtman JW. Age-associated synapse elimination in mouse parasympathetic ganglia. Journal of Neurobiology. 60: 214-26. PMID 15266652 DOI: 10.1002/Neu.20022 |
0.751 |
|
2004 |
Tsai J, Grutzendler J, Gan WB. Optical imaging of synaptic disruption in a mouse model of Alzheimer's disease Microscopy and Microanalysis. 10: 166-167. DOI: 10.1017/S1431927604883740 |
0.667 |
|
2003 |
Grutzendler J, Tsai J, Gan WB. Rapid labeling of neuronal populations by ballistic delivery of fluorescent dyes. Methods (San Diego, Calif.). 30: 79-85. PMID 12695105 DOI: 10.1016/S1046-2023(03)00009-4 |
0.663 |
|
2002 |
Grutzendler J, Kasthuri N, Gan WB. Long-term dendritic spine stability in the adult cortex. Nature. 420: 812-6. PMID 12490949 DOI: 10.1038/Nature01276 |
0.674 |
|
2001 |
Nadarajah B, Brunstrom JE, Grutzendler J, Wong RO, Pearlman AL. Two modes of radial migration in early development of the cerebral cortex. Nature Neuroscience. 4: 143-50. PMID 11175874 DOI: 10.1038/83967 |
0.332 |
|
2000 |
Gan WB, Grutzendler J, Wong WT, Wong RO, Lichtman JW. Multicolor "DiOlistic" labeling of the nervous system using lipophilic dye combinations. Neuron. 27: 219-25. PMID 10985343 DOI: 10.1016/S0896-6273(00)00031-3 |
0.771 |
|
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