Year |
Citation |
Score |
2022 |
Gaeta AL, Nourse JB, Willicott K, McKay LE, Keogh CM, Peter K, Russell SN, Hamamichi S, Berkowitz LA, Caldwell KA, Caldwell GA. Systemic RNA Interference Defective (SID) genes modulate dopaminergic neurodegeneration in C. elegans. Plos Genetics. 18: e1010115. PMID 35984862 DOI: 10.1371/journal.pgen.1010115 |
0.563 |
|
2014 |
Knight AL, Yan X, Hamamichi S, Ajjuri RR, Mazzulli JR, Zhang MW, Daigle JG, Zhang S, Borom AR, Roberts LR, Lee SK, DeLeon SM, Viollet-Djelassi C, Krainc D, O'Donnell JM, et al. The glycolytic enzyme, GPI, is a functionally conserved modifier of dopaminergic neurodegeneration in Parkinson's models. Cell Metabolism. 20: 145-57. PMID 24882066 DOI: 10.1016/J.Cmet.2014.04.017 |
0.586 |
|
2014 |
Matlack KE, Tardiff DF, Narayan P, Hamamichi S, Caldwell KA, Caldwell GA, Lindquist S. Clioquinol promotes the degradation of metal-dependent amyloid-β (Aβ) oligomers to restore endocytosis and ameliorate Aβ toxicity. Proceedings of the National Academy of Sciences of the United States of America. 111: 4013-8. PMID 24591589 DOI: 10.1073/Pnas.1402228111 |
0.566 |
|
2014 |
Muñoz-Lobato F, RodrÃguez-Palero MJ, Naranjo-Galindo FJ, Shephard F, Gaffney CJ, Szewczyk NJ, Hamamichi S, Caldwell KA, Caldwell GA, Link CD, Miranda-Vizuete A. Protective role of DNJ-27/ERdj5 in Caenorhabditis elegans models of human neurodegenerative diseases. Antioxidants & Redox Signaling. 20: 217-35. PMID 23641861 DOI: 10.1089/Ars.2012.5051 |
0.605 |
|
2011 |
Treusch S, Hamamichi S, Goodman JL, Matlack KE, Chung CY, Baru V, Shulman JM, Parrado A, Bevis BJ, Valastyan JS, Han H, Lindhagen-Persson M, Reiman EM, Evans DA, Bennett DA, et al. Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast. Science (New York, N.Y.). 334: 1241-5. PMID 22033521 DOI: 10.1126/Science.1213210 |
0.559 |
|
2011 |
Liu Z, Hamamichi S, Lee BD, Yang D, Ray A, Caldwell GA, Caldwell KA, Dawson TM, Smith WW, Dawson VL. Inhibitors of LRRK2 kinase attenuate neurodegeneration and Parkinson-like phenotypes in Caenorhabditis elegans and Drosophila Parkinson's disease models. Human Molecular Genetics. 20: 3933-42. PMID 21768216 DOI: 10.1093/Hmg/Ddr312 |
0.673 |
|
2010 |
Yacoubian TA, Slone SR, Harrington AJ, Hamamichi S, Schieltz JM, Caldwell KA, Caldwell GA, Standaert DG. Differential neuroprotective effects of 14-3-3 proteins in models of Parkinson's disease. Cell Death & Disease. 1: e2. PMID 21152247 DOI: 10.1038/Cddis.2009.4 |
0.75 |
|
2010 |
Harrington AJ, Hamamichi S, Caldwell GA, Caldwell KA. C. elegans as a model organism to investigate molecular pathways involved with Parkinson's disease. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 1282-95. PMID 20108318 DOI: 10.1002/Dvdy.22231 |
0.74 |
|
2010 |
Su LJ, Auluck PK, Outeiro TF, Yeger-Lotem E, Kritzer JA, Tardiff DF, Strathearn KE, Liu F, Cao S, Hamamichi S, Hill KJ, Caldwell KA, Bell GW, Fraenkel E, Cooper AA, et al. Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models. Disease Models & Mechanisms. 3: 194-208. PMID 20038714 DOI: 10.1242/Dmm.004267 |
0.74 |
|
2009 |
Kritzer JA, Hamamichi S, McCaffery JM, Santagata S, Naumann TA, Caldwell KA, Caldwell GA, Lindquist S. Rapid selection of cyclic peptides that reduce alpha-synuclein toxicity in yeast and animal models. Nature Chemical Biology. 5: 655-63. PMID 19597508 DOI: 10.1038/Nchembio.193 |
0.627 |
|
2009 |
Gitler AD, Chesi A, Geddie ML, Strathearn KE, Hamamichi S, Hill KJ, Caldwell KA, Caldwell GA, Cooper AA, Rochet JC, Lindquist S. Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity. Nature Genetics. 41: 308-15. PMID 19182805 DOI: 10.1038/Ng.300 |
0.733 |
|
2008 |
Berkowitz LA, Hamamichi S, Knight AL, Harrington AJ, Caldwell GA, Caldwell KA. Application of a C. elegans dopamine neuron degeneration assay for the validation of potential Parkinson's disease genes. Journal of Visualized Experiments : Jove. PMID 19066512 DOI: 10.3791/835 |
0.747 |
|
2008 |
Qiao L, Hamamichi S, Caldwell KA, Caldwell GA, Yacoubian TA, Wilson S, Xie ZL, Speake LD, Parks R, Crabtree D, Liang Q, Crimmins S, Schneider L, Uchiyama Y, Iwatsubo T, et al. Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity. Molecular Brain. 1: 17. PMID 19021916 DOI: 10.1186/1756-6606-1-17 |
0.601 |
|
2008 |
Hamamichi S, Rivas RN, Knight AL, Cao S, Caldwell KA, Caldwell GA. Hypothesis-based RNAi screening identifies neuroprotective genes in a Parkinson's disease model. Proceedings of the National Academy of Sciences of the United States of America. 105: 728-33. PMID 18182484 DOI: 10.1073/Pnas.0711018105 |
0.772 |
|
2008 |
Gitler AD, Bevis BJ, Shorter J, Strathearn KE, Hamamichi S, Su LJ, Caldwell KA, Caldwell GA, Rochet JC, McCaffery JM, Barlowe C, Lindquist S. The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 105: 145-50. PMID 18162536 DOI: 10.1073/Pnas.0710685105 |
0.677 |
|
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