Year |
Citation |
Score |
2024 |
Flanagan TW, Foster TP, Galbato TE, Lum PY, Louie B, Song G, Halberstadt AL, Billac GB, Nichols CD. Serotonin-2 Receptor Agonists Produce Anti-inflammatory Effects through Functionally Selective Mechanisms That Involve the Suppression of Disease-Induced Arginase 1 Expression. Acs Pharmacology & Translational Science. 7: 478-492. PMID 38357283 DOI: 10.1021/acsptsci.3c00297 |
0.353 |
|
2023 |
Wallach J, Cao AB, Calkins MM, Heim AJ, Lanham JK, Bonniwell EM, Hennessey JJ, Bock HA, Anderson EI, Sherwood AM, Morris H, de Klein R, Klein AK, Cuccurazzu B, Gamrat J, ... ... Halberstadt AL, et al. Identification of 5-HT receptor signaling pathways associated with psychedelic potential. Nature Communications. 14: 8221. PMID 38102107 DOI: 10.1038/s41467-023-44016-1 |
0.38 |
|
2023 |
Wallach J, Cao AB, Calkins MM, Heim AJ, Lanham JK, Bonniwell EM, Hennessey JJ, Bock HA, Anderson EI, Sherwood AM, Morris H, de Klein R, Klein AK, Cuccurazzu B, Gamrat J, ... ... Halberstadt AL, et al. Identification of 5-HT Receptor Signaling Pathways Responsible for Psychedelic Potential. Biorxiv : the Preprint Server For Biology. PMID 37577474 DOI: 10.1101/2023.07.29.551106 |
0.383 |
|
2023 |
Lewis V, Bonniwell EM, Lanham JK, Ghaffari A, Sheshbaradaran H, Cao AB, Calkins MM, Bautista-Carro MA, Arsenault E, Telfer A, Taghavi-Abkuh FF, Malcolm NJ, El Sayegh F, Abizaid A, Schmid Y, ... ... Halberstadt AL, et al. A non-hallucinogenic LSD analog with therapeutic potential for mood disorders. Cell Reports. 42: 112203. PMID 36884348 DOI: 10.1016/j.celrep.2023.112203 |
0.413 |
|
2021 |
Brandt SD, Kavanagh PV, Westphal F, Pulver B, Morton K, Stratford A, Dowling G, Halberstadt AL. Return of the lysergamides. Part VII: Analytical and behavioural characterization of 1-valeroyl-d-lysergic acid diethylamide (1V-LSD). Drug Testing and Analysis. PMID 34837347 DOI: 10.1002/dta.3205 |
0.31 |
|
2021 |
Rudin D, McCorvy JD, Glatfelter GC, Luethi D, Szöllősi D, Ljubišić T, Kavanagh PV, Dowling G, Holy M, Jaentsch K, Walther D, Brandt SD, Stockner T, Baumann MH, Halberstadt AL, et al. (2-Aminopropyl)benzo[β]thiophenes (APBTs) are novel monoamine transporter ligands that lack stimulant effects but display psychedelic-like activity in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34750565 DOI: 10.1038/s41386-021-01221-0 |
0.332 |
|
2021 |
Roberts BZ, Minassian A, Halberstadt AL, He YV, Chatha M, Geyer MA, Grant I, Young JW. HIV transgenic rats demonstrate impaired sensorimotor gating, but are insensitive to cannabinoid (Δ9-tetrahydrocannabinol)-induced deficits. The International Journal of Neuropsychopharmacology. PMID 34338765 DOI: 10.1093/ijnp/pyab053 |
0.489 |
|
2021 |
Klein AK, Chatha M, Laskowski LJ, Anderson EI, Brandt SD, Chapman SJ, McCorvy JD, Halberstadt AL. Investigation of the Structure-Activity Relationships of Psilocybin Analogues. Acs Pharmacology & Translational Science. 4: 533-542. PMID 33860183 DOI: 10.1021/acsptsci.0c00176 |
0.412 |
|
2021 |
Barnes NM, Ahern GP, Becamel C, Bockaert J, Camilleri M, Chaumont-Dubel S, Claeysen S, Cunningham KA, Fone KC, Gershon M, Di Giovanni G, Goodfellow NM, Halberstadt AL, Hartley RM, Hassaine G, et al. International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function. Pharmacological Reviews. 73: 310-520. PMID 33370241 DOI: 10.1124/pr.118.015552 |
0.364 |
|
2020 |
Amodeo DA, Hassan O, Klein L, Halberstadt AL, Powell SB. Acute serotonin 2A receptor activation impairs behavioral flexibility in mice. Behavioural Brain Research. 395: 112861. PMID 32814148 DOI: 10.1016/J.Bbr.2020.112861 |
0.778 |
|
2020 |
Jensen AA, Halberstadt AL, Märcher-Rørsted E, Odland AU, Chatha M, Speth N, Liebscher G, Hansen M, Bräuner-Osborne H, Palner M, Andreasen JT, Kristensen JL. The selective 5-HT receptor agonist 25CN-NBOH: Structure-activity relationship, in vivo pharmacology, and in vitro and ex vivo binding characteristics of [H]25CN-NBOH. Biochemical Pharmacology. 177: 113979. PMID 32298690 DOI: 10.1016/J.Bcp.2020.113979 |
0.445 |
|
2020 |
Marcher-Rørsted E, Halberstadt AL, Klein AK, Chatha M, Jademyr S, Jensen AA, Kristensen JL. Investigation of the 2,5-dimethoxy motif in phenethylamine Serotonin 2A receptor agonists. Acs Chemical Neuroscience. PMID 32212672 DOI: 10.1021/Acschemneuro.0C00129 |
0.422 |
|
2020 |
Sherwood AM, Halberstadt AL, Klein AK, McCorvy JD, Kaylo KW, Kargbo RB, Meisenheimer P. Synthesis and Biological Evaluation of Tryptamines Found in Hallucinogenic Mushrooms: Norbaeocystin, Baeocystin, Norpsilocin, and Aeruginascin. Journal of Natural Products. PMID 32077284 DOI: 10.1021/Acs.Jnatprod.9B01061 |
0.422 |
|
2020 |
Halberstadt AL, Chatha M, Klein AK, Wallach J, Brandt SD. Correlation between the potency of hallucinogens in the mouse head-twitch response assay and their behavioral and subjective effects in other species. Neuropharmacology. 107933. PMID 31917152 DOI: 10.1016/J.Neuropharm.2019.107933 |
0.469 |
|
2019 |
Halberstadt AL, Chatha M, Klein AK, McCorvy JD, Meyer MR, Wagmann L, Stratford A, Brandt SD. Pharmacological and biotransformation studies of 1-acyl-substituted derivatives of d-lysergic acid diethylamide (LSD). Neuropharmacology. 107856. PMID 31756337 DOI: 10.1016/J.Neuropharm.2019.107856 |
0.477 |
|
2019 |
Poulie CBM, Jensen AA, Halberstadt AL, Kristensen JL. DARK Classics in Chemical Neuroscience: NBOMes. Acs Chemical Neuroscience. PMID 31657895 DOI: 10.1021/Acschemneuro.9B00528 |
0.469 |
|
2019 |
Wallach J, Colestock T, Agramunt J, Claydon MDB, Dybek M, Filemban N, Chatha M, Halberstadt AL, Brandt SD, Lodge D, Bortolotto ZA, Adejare A. Pharmacological characterizations of the legal high fluorolintane and isomers. European Journal of Pharmacology. 172427. PMID 31152702 DOI: 10.1016/J.Ejphar.2019.172427 |
0.415 |
|
2019 |
Brandt SD, Kavanagh PV, Westphal F, Stratford A, Elliott SP, Dowling G, Wallach J, Halberstadt AL. Return of the lysergamides. Part V: Analytical and behavioural characterization of 1-butanoyl-d-lysergic acid diethylamide (1B-LSD). Drug Testing and Analysis. PMID 31083768 DOI: 10.1002/Dta.2613 |
0.378 |
|
2019 |
Young JW, Geyer MA, Halberstadt AL, van Enkhuizen J, Minassian A, Khan A, Perry W, Eyler LT. Convergent neural substrates of inattention in bipolar disorder patients and dopamine transporter-deficient mice using the 5-choice CPT. Bipolar Disorders. PMID 31025493 DOI: 10.1111/Bdi.12786 |
0.536 |
|
2019 |
Halberstadt AL, Chatha M, Chapman SJ, Brandt SD. Comparison of the behavioral effects of mescaline analogs using the head twitch response in mice. Journal of Psychopharmacology (Oxford, England). 269881119826610. PMID 30789291 DOI: 10.1177/0269881119826610 |
0.366 |
|
2018 |
Halberstadt AL, van der Zee JVF, Chatha M, Geyer MA, Powell SB. Chronic treatment with a metabotropic mGlu2/3 receptor agonist diminishes behavioral response to a phenethylamine hallucinogen. Psychopharmacology. PMID 30448990 DOI: 10.1007/S00213-018-5118-Y |
0.737 |
|
2018 |
Halberstadt AL, Klein LM, Chatha M, Valenzuela LB, Stratford A, Wallach J, Nichols DE, Brandt SD. Correction to: Pharmacological characterization of the LSD analog N-ethyl-N-cyclopropyl lysergamide (ECPLA). Psychopharmacology. PMID 30443792 DOI: 10.1007/S00213-018-5117-Z |
0.598 |
|
2018 |
Halberstadt AL, Chatha M, Stratford A, Grill M, Brandt SD. Comparison of the behavioral responses induced by phenylalkylamine hallucinogens and their tetrahydrobenzodifuran ("FLY") and benzodifuran ("DragonFLY") analogs. Neuropharmacology. PMID 30385253 DOI: 10.1016/J.Neuropharm.2018.10.037 |
0.332 |
|
2018 |
Halberstadt AL, Klein LM, Chatha M, Valenzuela LB, Stratford A, Wallach J, Nichols DE, Brandt SD. Pharmacological characterization of the LSD analog N-ethyl-N-cyclopropyl lysergamide (ECPLA). Psychopharmacology. PMID 30298278 DOI: 10.1007/S00213-018-5055-9 |
0.585 |
|
2018 |
Klein LM, Cozzi NV, Daley PF, Brandt SD, Halberstadt AL. Receptor binding profiles and behavioral pharmacology of ring-substituted N,N-diallyltryptamine analogs. Neuropharmacology. PMID 29499272 DOI: 10.1016/J.Neuropharm.2018.02.028 |
0.683 |
|
2017 |
Brandt SD, Kavanagh PV, Twamley B, Westphal F, Elliott SP, Wallach J, Stratford A, Klein LM, McCorvy JD, Nichols DE, Halberstadt AL. Return of the lysergamides. Part IV: Analytical and pharmacological characterization of lysergic acid morpholide (LSM-775). Drug Testing and Analysis. PMID 28585392 DOI: 10.1002/Dta.2222 |
0.644 |
|
2017 |
Halberstadt AL, Geyer MA. Effect of Hallucinogens on Unconditioned Behavior. Current Topics in Behavioral Neurosciences. PMID 28224459 DOI: 10.1007/7854_2016_466 |
0.523 |
|
2017 |
Halberstadt AL. Hallucinogenic Drugs: A New Study Answers Old Questions about LSD. Current Biology : Cb. 27: R156-R158. PMID 28222297 DOI: 10.1016/J.Cub.2016.12.058 |
0.384 |
|
2017 |
Halberstadt AL. Pharmacology and Toxicology of N-Benzylphenethylamine ("NBOMe") Hallucinogens. Current Topics in Behavioral Neurosciences. PMID 28097528 DOI: 10.1007/7854_2016_64 |
0.395 |
|
2016 |
Cope ZA, Halberstadt AL, van Enkhuizen J, Flynn AD, Breier M, Swerdlow NR, Geyer MA, Young JW. Premature responses in the five-choice serial reaction time task reflect rodents' temporal strategies: evidence from no-light and pharmacological challenges. Psychopharmacology. PMID 27534540 DOI: 10.1007/S00213-016-4389-4 |
0.537 |
|
2016 |
Wallach J, Kang H, Colestock T, Morris H, Bortolotto ZA, Collingridge GL, Lodge D, Halberstadt AL, Brandt SD, Adejare A. Pharmacological Investigations of the Dissociative 'Legal Highs' Diphenidine, Methoxphenidine and Analogues. Plos One. 11: e0157021. PMID 27314670 DOI: 10.1371/Journal.Pone.0157021 |
0.43 |
|
2016 |
Brandt SD, Kavanagh PV, Westphal F, Elliott SP, Wallach J, Colestock T, Burrow TE, Chapman SJ, Stratford A, Nichols DE, Halberstadt AL. Return of the lysergamides. Part II: Analytical and behavioural characterization of N(6) -allyl-6-norlysergic acid diethylamide (AL-LAD) and (2'S,4'S)-lysergic acid 2,4-dimethylazetidide (LSZ). Drug Testing and Analysis. PMID 27265891 DOI: 10.1002/Dta.1985 |
0.319 |
|
2016 |
Halberstadt AL, Hyun J, Ruderman MA, Powell SB. Effects of the psychotomimetic benzomorphan N-allylnormetazocine (SKF 10,047) on prepulse inhibition of startle in mice. Pharmacology, Biochemistry, and Behavior. PMID 27236030 DOI: 10.1016/J.Pbb.2016.05.009 |
0.677 |
|
2016 |
Halberstadt AL, Sindhunata I, Scheffers K, Flynn AD, Sharp RF, Geyer MA, Young JW. Effect of 5-HT2A and 5-HT2C receptors on temporal discrimination by mice. Neuropharmacology. PMID 27020041 DOI: 10.1016/J.Neuropharm.2016.03.038 |
0.667 |
|
2016 |
Halberstadt AL. Behavioral and pharmacokinetic interactions between monoamine oxidase inhibitors and the hallucinogen 5-methoxy-N,N-dimethyltryptamine. Pharmacology, Biochemistry, and Behavior. PMID 26780349 DOI: 10.1016/J.Pbb.2016.01.005 |
0.445 |
|
2016 |
Halberstadt AL, Slepak N, Hyun J, Buell MR, Powell SB. The novel ketamine analog methoxetamine produces dissociative-like behavioral effects in rodents. Psychopharmacology. PMID 26758284 DOI: 10.1007/S00213-016-4203-3 |
0.648 |
|
2016 |
Geyer M, Halberstadt A. Behavioural and pharmacological studies of pharmahuasca in rodents European Neuropsychopharmacology. 26: S120. DOI: 10.1016/S0924-977X(16)30889-6 |
0.339 |
|
2015 |
Brandt SD, Kavanagh PV, Westphal F, Stratford A, Elliott SP, Hoang K, Wallach J, Halberstadt AL. Return of the lysergamides. Part I: Analytical and behavioural characterization of 1-propionyl-d-lysergic acid diethylamide (1P-LSD). Drug Testing and Analysis. PMID 26456305 DOI: 10.1002/Dta.1884 |
0.405 |
|
2015 |
Manning EE, Halberstadt AL, van den Buuse M. BDNF-Deficient Mice Show Reduced Psychosis-Related Behaviors Following Chronic Methamphetamine. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 26453694 DOI: 10.1093/Ijnp/Pyv116 |
0.315 |
|
2015 |
Nichols DE, Sassano MF, Halberstadt AL, Klein LM, Brandt SD, Elliott SP, Fiedler WJ. N-Benzyl-5-methoxytryptamines as Potent Serotonin 5-HT2 Receptor Family Agonists and Comparison with a Series of Phenethylamine Analogues. Acs Chemical Neuroscience. 6: 1165-75. PMID 25547199 DOI: 10.1021/Cn500292D |
0.687 |
|
2015 |
Halberstadt AL. Recent advances in the neuropsychopharmacology of serotonergic hallucinogens. Behavioural Brain Research. 277: 99-120. PMID 25036425 DOI: 10.1016/J.Bbr.2014.07.016 |
0.426 |
|
2014 |
van Enkhuizen J, Geyer MA, Halberstadt AL, Zhuang X, Young JW. Dopamine depletion attenuates some behavioral abnormalities in a hyperdopaminergic mouse model of bipolar disorder. Journal of Affective Disorders. 155: 247-54. PMID 24287168 DOI: 10.1016/J.Jad.2013.08.041 |
0.596 |
|
2014 |
Halberstadt AL, Geyer MA. Effects of the hallucinogen 2,5-dimethoxy-4-iodophenethylamine (2C-I) and superpotent N-benzyl derivatives on the head twitch response. Neuropharmacology. 77: 200-7. PMID 24012658 DOI: 10.1016/J.Neuropharm.2013.08.025 |
0.606 |
|
2013 |
Adams WK, Halberstadt AL, van den Buuse M. Hippocampal serotonin depletion unmasks differences in the hyperlocomotor effects of phencyclidine and MK-801: quantitative versus qualitative analyses. Frontiers in Pharmacology. 4: 109. PMID 24009584 DOI: 10.3389/Fphar.2013.00109 |
0.397 |
|
2013 |
Halberstadt AL, Geyer MA. Serotonergic hallucinogens as translational models relevant to schizophrenia. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 2165-80. PMID 23942028 DOI: 10.1017/S1461145713000722 |
0.509 |
|
2013 |
Toth M, Gresack JE, Hauger RL, Halberstadt AL, Risbrough VB. The role of PKC signaling in CRF-induced modulation of startle. Psychopharmacology. 229: 579-89. PMID 23722830 DOI: 10.1007/S00213-013-3114-9 |
0.545 |
|
2013 |
Halberstadt AL, Geyer MA. Characterization of the head-twitch response induced by hallucinogens in mice: detection of the behavior based on the dynamics of head movement. Psychopharmacology. 227: 727-39. PMID 23407781 DOI: 10.1007/S00213-013-3006-Z |
0.49 |
|
2013 |
Halberstadt AL, Powell SB, Geyer MA. Role of the 5-HTâ‚‚A receptor in the locomotor hyperactivity produced by phenylalkylamine hallucinogens in mice. Neuropharmacology. 70: 218-27. PMID 23376711 DOI: 10.1016/J.Neuropharm.2013.01.014 |
0.745 |
|
2013 |
Amitai N, Weber M, Swerdlow NR, Sharp RF, Breier MR, Halberstadt AL, Young JW. A novel visuospatial priming task for rats with relevance to Tourette syndrome and modulation of dopamine levels. Neuroscience and Biobehavioral Reviews. 37: 1139-49. PMID 23010529 DOI: 10.1016/J.Neubiorev.2012.09.007 |
0.459 |
|
2012 |
Tanaka S, Young JW, Halberstadt AL, Masten VL, Geyer MA. Four factors underlying mouse behavior in an open field. Behavioural Brain Research. 233: 55-61. PMID 22569582 DOI: 10.1016/J.Bbr.2012.04.045 |
0.57 |
|
2012 |
Halberstadt AL, Buell MR, Price DL, Geyer MA. Differences in the locomotor-activating effects of indirect serotonin agonists in habituated and non-habituated rats. Pharmacology, Biochemistry, and Behavior. 102: 88-94. PMID 22487771 DOI: 10.1016/J.Pbb.2012.03.023 |
0.621 |
|
2012 |
Halberstadt AL, Nichols DE, Geyer MA. Behavioral effects of α,α,β,β-tetradeutero-5-MeO-DMT in rats: comparison with 5-MeO-DMT administered in combination with a monoamine oxidase inhibitor. Psychopharmacology. 221: 709-18. PMID 22222861 DOI: 10.1007/S00213-011-2616-6 |
0.533 |
|
2011 |
van den Buuse M, Ruimschotel E, Martin S, Risbrough VB, Halberstadt AL. Enhanced effects of amphetamine but reduced effects of the hallucinogen, 5-MeO-DMT, on locomotor activity in 5-HT(1A) receptor knockout mice: implications for schizophrenia. Neuropharmacology. 61: 209-16. PMID 21501627 DOI: 10.1016/J.Neuropharm.2011.04.001 |
0.678 |
|
2011 |
Halberstadt AL, Geyer MA. Multiple receptors contribute to the behavioral effects of indoleamine hallucinogens. Neuropharmacology. 61: 364-81. PMID 21256140 DOI: 10.1016/J.Neuropharm.2011.01.017 |
0.627 |
|
2011 |
Halberstadt AL, Lehmann-Masten VD, Geyer MA, Powell SB. Interactive effects of mGlu5 and 5-HT2A receptors on locomotor activity in mice. Psychopharmacology. 215: 81-92. PMID 21153406 DOI: 10.1007/S00213-010-2115-1 |
0.751 |
|
2011 |
Halberstadt AL, Koedood L, Powell SB, Geyer MA. Differential contributions of serotonin receptors to the behavioral effects of indoleamine hallucinogens in mice. Journal of Psychopharmacology (Oxford, England). 25: 1548-61. PMID 21148021 DOI: 10.1177/0269881110388326 |
0.744 |
|
2010 |
Halberstadt AL, Geyer MA. LSD but not lisuride disrupts prepulse inhibition in rats by activating the 5-HT(2A) receptor. Psychopharmacology. 208: 179-89. PMID 19937319 DOI: 10.1007/S00213-009-1718-X |
0.609 |
|
2010 |
Halberstadt AL, Nichols DE. Serotonin and serotonin receptors in hallucinogen action Handbook of Behavioral Neuroscience. 21: 621-636. DOI: 10.1016/S1569-7339(10)70103-X |
0.47 |
|
2010 |
Quednow BB, Geyer MA, Halberstadt AL. Serotonin and Schizophrenia Handbook of Behavioral Neuroscience. 21: 585-620. DOI: 10.1016/S1569-7339(10)70102-8 |
0.349 |
|
2009 |
Halberstadt AL, van der Heijden I, Ruderman MA, Risbrough VB, Gingrich JA, Geyer MA, Powell SB. 5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1958-67. PMID 19322172 DOI: 10.1038/Npp.2009.29 |
0.774 |
|
2009 |
Halberstadt AL, Geyer MA. Habituation and sensitization of acoustic startle: opposite influences of dopamine D1 and D2-family receptors. Neurobiology of Learning and Memory. 92: 243-8. PMID 18644244 DOI: 10.1016/J.Nlm.2008.05.015 |
0.495 |
|
2008 |
Halberstadt AL, Buell MR, Masten VL, Risbrough VB, Geyer MA. Modification of the effects of 5-methoxy-N,N-dimethyltryptamine on exploratory behavior in rats by monoamine oxidase inhibitors. Psychopharmacology. 201: 55-66. PMID 18604652 DOI: 10.1007/S00213-008-1247-Z |
0.705 |
|
2008 |
Halberstadt AL, Balaban CD. Selective anterograde tracing of nonserotonergic projections from dorsal raphe nucleus to the basal forebrain and extended amygdala. Journal of Chemical Neuroanatomy. 35: 317-25. PMID 18434087 DOI: 10.1016/J.Jchemneu.2008.02.006 |
0.519 |
|
2007 |
Halberstadt AL, Balaban CD. Selective anterograde tracing of the individual serotonergic and nonserotonergic components of the dorsal raphe nucleus projection to the vestibular nuclei. Neuroscience. 147: 207-23. PMID 17507165 DOI: 10.1016/J.Neuroscience.2007.03.049 |
0.533 |
|
2006 |
Halberstadt AL, Balaban CD. Anterograde tracing of projections from the dorsal raphe nucleus to the vestibular nuclei. Neuroscience. 143: 641-54. PMID 16989955 DOI: 10.1016/J.Neuroscience.2006.08.013 |
0.509 |
|
2006 |
Halberstadt AL, Balaban CD. Serotonergic and nonserotonergic neurons in the dorsal raphe nucleus send collateralized projections to both the vestibular nuclei and the central amygdaloid nucleus. Neuroscience. 140: 1067-77. PMID 16600519 DOI: 10.1016/J.Neuroscience.2006.02.053 |
0.526 |
|
2003 |
Halberstadt AL, Balaban CD. Organization of projections from the raphe nuclei to the vestibular nuclei in rats. Neuroscience. 120: 573-94. PMID 12890525 DOI: 10.1016/S0306-4522(02)00952-1 |
0.534 |
|
1995 |
Halberstadt AL. The phencyclidine-glutamate model of schizophrenia. Clinical Neuropharmacology. 18: 237-49. PMID 8635182 DOI: 10.1097/00002826-199506000-00004 |
0.321 |
|
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