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Clinton E. Leysath, Ph.D. - Publications

Affiliations: 
2008 Institute for Cellular and Molecular Biology University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Antibody and Enzyme Engineering
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8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Chen KH, Liu S, Leysath CE, Miller-Randolph S, Zhang Y, Fattah R, Bugge TH, Leppla SH. Anthrax Toxin Protective Antigen Variants that selectively utilize either the CMG2 or TEM8 Receptors for Cellular Uptake and Tumor Targeting. The Journal of Biological Chemistry. PMID 27555325 DOI: 10.1074/jbc.M116.753301  0.349
2015 Moayeri M, Leysath CE, Tremblay JM, Vrentas C, Crown D, Leppla SH, Shoemaker CB. A heterodimer of a VHH (variable domains of camelid heavy chain-only) antibody that inhibits anthrax toxin cell binding linked to a VHH antibody that blocks oligomer formation is highly protective in an anthrax spore challenge model. The Journal of Biological Chemistry. 290: 6584-95. PMID 25564615 DOI: 10.1074/jbc.M114.627943  0.554
2013 Tremblay JM, Mukherjee J, Leysath CE, Debatis M, Ofori K, Baldwin K, Boucher C, Peters R, Beamer G, Sheoran A, Bedenice D, Tzipori S, Shoemaker CB. A single VHH-based toxin-neutralizing agent and an effector antibody protect mice against challenge with Shiga toxins 1 and 2. Infection and Immunity. 81: 4592-603. PMID 24082082 DOI: 10.1128/Iai.01033-13  0.471
2012 Mukherjee J, Tremblay JM, Leysath CE, Ofori K, Baldwin K, Feng X, Bedenice D, Webb RP, Wright PM, Smith LA, Tzipori S, Shoemaker CB. A novel strategy for development of recombinant antitoxin therapeutics tested in a mouse botulism model. Plos One. 7: e29941. PMID 22238680 DOI: 10.1371/journal.pone.0029941  0.323
2011 Leysath CE, Chen KH, Moayeri M, Crown D, Fattah R, Chen Z, Das SR, Purcell RH, Leppla SH. Mouse monoclonal antibodies to anthrax edema factor protect against infection. Infection and Immunity. 79: 4609-16. PMID 21911463 DOI: 10.1128/IAI.05314-11  0.567
2010 Radjainia M, Hyun JK, Leysath CE, Leppla SH, Mitra AK. Anthrax toxin-neutralizing antibody reconfigures the protective antigen heptamer into a supercomplex. Proceedings of the National Academy of Sciences of the United States of America. 107: 14070-4. PMID 20660775 DOI: 10.1073/Pnas.1006473107  0.561
2009 Leysath CE, Monzingo AF, Maynard JA, Barnett J, Georgiou G, Iverson BL, Robertus JD. Crystal structure of the engineered neutralizing antibody M18 complexed to domain 4 of the anthrax protective antigen. Journal of Molecular Biology. 387: 680-93. PMID 19361425 DOI: 10.1016/J.Jmb.2009.02.003  0.385
2009 Seo MJ, Jeong KJ, Leysath CE, Ellington AD, Iverson BL, Georgiou G. Engineering antibody fragments to fold in the absence of disulfide bonds. Protein Science : a Publication of the Protein Society. 18: 259-67. PMID 19177559 DOI: 10.1002/Pro.31  0.383
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