Christopher J. Holler, Ph.D. - Publications

Affiliations: 
2012 Molecular and Cellular Biochemistry University of Kentucky, Lexington, KY 
Area:
Alzheimer\'s disease

13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Root J, Mendsaikhan A, Nandy S, Taylor G, Wang M, Troiano Araujo L, Merino P, Ryu D, Holler C, Thompson BM, Astarita G, Blain Jß, Kukar T. Granulins rescue inflammation, lysosome dysfunction, and neuropathology in a mouse model of progranulin deficiency. Biorxiv : the Preprint Server For Biology. PMID 37131734 DOI: 10.1101/2023.04.17.536004  0.363
2020 Huang M, Modeste E, Dammer E, Merino P, Taylor G, Duong DM, Deng Q, Holler CJ, Gearing M, Dickson D, Seyfried NT, Kukar T. Network analysis of the progranulin-deficient mouse brain proteome reveals pathogenic mechanisms shared in human frontotemporal dementia caused by GRN mutations. Acta Neuropathologica Communications. 8: 163. PMID 33028409 DOI: 10.1186/s40478-020-01037-x  0.332
2020 McEachin ZT, Gendron TF, Raj N, García-Murias M, Banerjee A, Purcell RH, Ward PJ, Todd TW, Merritt-Garza ME, Jansen-West K, Hales CM, García-Sobrino T, Quintáns B, Holler CJ, Taylor G, et al. Chimeric Peptide Species Contribute to Divergent Dipeptide Repeat Pathology in c9ALS/FTD and SCA36. Neuron. PMID 32375063 DOI: 10.1016/J.Neuron.2020.04.011  0.339
2017 Holler C, Taylor G, Kukar T. GRANULINS ARE STABLE LYSOSOMAL PROTEINS: IMPLICATIONS FOR THE ROLE OF PROGRANULIN IN ALZHEIMER’S DISEASE Alzheimer's & Dementia. 13: P556-P557. DOI: 10.1016/J.Jalz.2017.07.160  0.362
2016 Holler CJ, Taylor G, McEachin ZT, Deng Q, Watkins WJ, Hudson K, Easley CA, Hu WT, Hales CM, Rossoll W, Bassell GJ, Kukar T. Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia. Molecular Neurodegeneration. 11: 46. PMID 27341800 DOI: 10.1186/S13024-016-0114-3  0.414
2014 Holler CJ, Davis PR, Beckett TL, Platt TL, Webb RL, Head E, Murphy MP. Bridging integrator 1 (BIN1) protein expression increases in the Alzheimer's disease brain and correlates with neurofibrillary tangle pathology. Journal of Alzheimer's Disease : Jad. 42: 1221-7. PMID 25024306 DOI: 10.3233/Jad-132450  0.588
2013 Holler CJ, Murphy MP. BACE1: Expression, regulation, and therapeutic potential of the major Alzheimer's disease beta-Secretase Current Enzyme Inhibition. 9: 3-14. DOI: 10.2174/1573408011309010003  0.49
2012 Beckett TL, Webb RL, Niedowicz DM, Holler CJ, Matveev S, Baig I, LeVine H, Keller JN, Murphy MP. Postmortem Pittsburgh Compound B (PiB) binding increases with Alzheimer's disease progression. Journal of Alzheimer's Disease : Jad. 32: 127-38. PMID 22766739 DOI: 10.3233/Jad-2012-120655  0.585
2012 Holler CJ, Webb RL, Laux AL, Beckett TL, Niedowicz DM, Ahmed RR, Liu Y, Simmons CR, Dowling AL, Spinelli A, Khurgel M, Estus S, Head E, Hersh LB, Murphy MP. BACE2 expression increases in human neurodegenerative disease. The American Journal of Pathology. 180: 337-50. PMID 22074738 DOI: 10.1016/J.Ajpath.2011.09.034  0.594
2010 Niedowicz DM, Beckett TL, Holler CJ, Weidner AM, Murphy MP. APP(DeltaNL695) expression in murine tissue downregulates CNBP expression. Neuroscience Letters. 482: 57-61. PMID 20621159 DOI: 10.1016/J.Neulet.2010.07.006  0.579
2010 Beckett TL, Niedowicz DM, Studzinski CM, Weidner AM, Webb RL, Holler CJ, Ahmed RR, LeVine H, Murphy MP. Effects of nonsteroidal anti-inflammatory drugs on amyloid-beta pathology in mouse skeletal muscle. Neurobiology of Disease. 39: 449-56. PMID 20493261 DOI: 10.1016/J.Nbd.2010.05.018  0.53
2010 Ahmed RR, Holler CJ, Webb RL, Li F, Beckett TL, Murphy MP. BACE1 and BACE2 enzymatic activities in Alzheimer's disease. Journal of Neurochemistry. 112: 1045-53. PMID 19968762 DOI: 10.1111/J.1471-4159.2009.06528.X  0.622
2007 Holler C, Vaughan D, Zhang C. Polyethyleneimine precipitation versus anion exchange chromatography in fractionating recombinant beta-glucuronidase from transgenic tobacco extract. Journal of Chromatography. A. 1142: 98-105. PMID 16950325 DOI: 10.1016/J.Chroma.2006.08.044  0.307
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