| Year |
Citation |
Score |
| 2023 |
Ciulla DA, Xu Z, Pezzullo JL, Dranchak P, Wang C, Giner JL, Inglese J, Callahan BP. Paracatalytic induction: Subverting specificity in hedgehog protein autoprocessing with small molecules. Methods in Enzymology. 685: 1-41. PMID 37245899 DOI: 10.1016/bs.mie.2023.03.001 |
0.785 |
|
| 2023 |
Callahan BP, Xu Z. There's more to enzyme antagonism than inhibition. Bioorganic & Medicinal Chemistry. 82: 117231. PMID 36893527 DOI: 10.1016/j.bmc.2023.117231 |
0.361 |
|
| 2022 |
Ciulla DA, Dranchak P, Pezzullo JL, Mancusi RA, Psaras AM, Rai G, Giner JL, Inglese J, Callahan BP. A cell-based bioluminescence reporter assay of human Sonic Hedgehog protein autoprocessing to identify inhibitors and activators. The Journal of Biological Chemistry. 102705. PMID 36400200 DOI: 10.1016/j.jbc.2022.102705 |
0.779 |
|
| 2021 |
Wagner AG, Stagnitta RT, Xu Z, Pezzullo JL, Kandel N, Giner JL, Covey DF, Wang C, Callahan BP. Nanomolar, Noncovalent Antagonism of Hedgehog Cholesterolysis: Exception to the "Irreversibility Rule" for Protein Autoprocessing Inhibition. Biochemistry. PMID 34941260 DOI: 10.1021/acs.biochem.1c00697 |
0.706 |
|
| 2020 |
Callahan BP, Ciulla DA, Wagner AG, Xu Z, Zhang X. Specificity Distorted: Chemical Induction of Biological Paracatalysis. Biochemistry. PMID 32931253 DOI: 10.1021/acs.biochem.0c00643 |
0.734 |
|
| 2020 |
Smith CJ, Wagner AG, Stagnitta RT, Xu Z, Pezzullo JL, Giner JL, Xie J, Covey DF, Wang C, Callahan BP. Subverting Hedgehog Protein Autoprocessing by Chemical Induction of Paracatalysis. Biochemistry. PMID 32013401 DOI: 10.1021/Acs.Biochem.0C00013 |
0.736 |
|
| 2019 |
Zhao J, Ciulla DA, Xie J, Castillo DA, Wagner A, Zwarycz AS, Lin Z, Beadle S, Giner JL, Li Z, Li H, Banavali N, Callahan BP, Wang C. General Base Swap Preserves Activity and Expands Substrate Tolerance in Hedgehog Autoprocessing. Journal of the American Chemical Society. PMID 31682419 DOI: 10.1021/Jacs.9B08914 |
0.75 |
|
| 2019 |
Zhang X, Xu Z, Moumin DS, Ciulla DA, Owen TS, Mancusi RA, Giner JL, Wang C, Callahan BP. Protein-Nucleic Acid Conjugation with Sterol Linkers Using Hedgehog Autoprocessing. Bioconjugate Chemistry. PMID 31600061 DOI: 10.1021/Acs.Bioconjchem.9B00550 |
0.765 |
|
| 2019 |
Ciulla DA, Wagner AG, Liu X, Cooper CL, Jorgensen MT, Wang C, Goyal P, Banavali NK, Pezzullo JL, Giner JL, Callahan BP. Sterol A-ring plasticity in hedgehog protein cholesterolysis supports a primitive substrate selectivity mechanism. Chemical Communications (Cambridge, England). PMID 30672911 DOI: 10.1039/C8Cc09729A |
0.733 |
|
| 2017 |
Ciulla D, Jorgensen M, Giner JL, Callahan BP. Chemical bypass of general base catalysis in hedgehog protein cholesterolysis using a hyper-nucleophilic substrate. Journal of the American Chemical Society. PMID 28930454 DOI: 10.1021/jacs.7b05161 |
0.773 |
|
| 2016 |
Bordeau BM, Ciulla DA, Callahan BP. Hedgehog Proteins Consume Steroidal CYP17A1 Antagonists: Potential Therapeutic Significance in Advanced Prostate Cancer. Chemmedchem. PMID 27435344 DOI: 10.1002/cmdc.201600238 |
0.746 |
|
| 2015 |
Owen TS, Xie XJ, Laraway B, Ngoje G, Wang C, Callahan BP. Active site targeting of hedgehog precursor protein with phenylarsine oxide. Chembiochem : a European Journal of Chemical Biology. 16: 55-8. PMID 25418613 DOI: 10.1002/Cbic.201402421 |
0.331 |
|
| 2014 |
Callahan BP, Belfort M. Branching out of the intein active site in protein splicing Proceedings of the National Academy of Sciences of the United States of America. 111: 8323-8324. PMID 24872446 DOI: 10.1073/Pnas.1407116111 |
0.354 |
|
| 2009 |
Amitai G, Callahan BP, Stanger MJ, Belfort G, Belfort M. Modulation of intein activity by its neighboring extein substrates Proceedings of the National Academy of Sciences of the United States of America. 106: 11005-11010. PMID 19541659 DOI: 10.1073/Pnas.0904366106 |
0.354 |
|
| 2007 |
Callahan BP, Miller BG. OMP decarboxylase-An enigma persists Bioorganic Chemistry. 35: 465-469. PMID 17889251 DOI: 10.1016/J.Bioorg.2007.07.004 |
0.496 |
|
| 2006 |
Callahan BP, Lomino JV, Wolfenden R. Nanomolar inhibition of the enterobactin biosynthesis enzyme, EntE: synthesis, substituent effects, and additivity. Bioorganic & Medicinal Chemistry Letters. 16: 3802-5. PMID 16678412 DOI: 10.1016/J.Bmcl.2006.04.024 |
0.598 |
|
| 2006 |
Callahan BP, Bell AF, Tonge PJ, Wolfenden R. A Raman-active competitive inhibitor of OMP decarboxylase. Bioorganic Chemistry. 34: 59-65. PMID 16457871 DOI: 10.1016/J.Bioorg.2005.12.001 |
0.588 |
|
| 2005 |
Callahan BP, Yuan Y, Wolfenden R. The burden borne by urease. Journal of the American Chemical Society. 127: 10828-9. PMID 16076178 DOI: 10.1021/Ja0525399 |
0.562 |
|
| 2005 |
Callahan BP, Wolfenden R. Orotidine Monophosphate Decarboxylase: A Mechanistic Dialogue. Topics in Current Chemistry, 238 Edited by Jeehiun K. Lee (Rutgers University) and Dean J. Tantillo (University of California, Davis). Springer-Verlag: Berlin, Heidelberg, New York. 2004. x + 152 pp. $139.00. ISBN 3-540-20566-7. Journal of the American Chemical Society. 127: 4541-4541. DOI: 10.1021/Ja040982Y |
0.405 |
|
| 2004 |
Callahan BP, Wolfenden R. OMP decarboxylase: an experimental test of electrostatic destabilization of the enzyme-substrate complex. Journal of the American Chemical Society. 126: 14698-9. PMID 15535676 DOI: 10.1021/Ja0450049 |
0.597 |
|
| 2004 |
Callahan BP, Wolfenden R. Charge development in the transition state for decarboxylations in water: spontaneous and acetone-catalyzed decarboxylation of aminomalonate. Journal of the American Chemical Society. 126: 4514-5. PMID 15070358 DOI: 10.1021/Ja031720J |
0.545 |
|
| 2003 |
Callahan BP, Wolfenden R. Migration of methyl groups between aliphatic amines in water. Journal of the American Chemical Society. 125: 310-1. PMID 12517124 DOI: 10.1021/Ja021212U |
0.537 |
|
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