Year |
Citation |
Score |
2023 |
Ciulla DA, Xu Z, Pezzullo JL, Dranchak P, Wang C, Giner JL, Inglese J, Callahan BP. Paracatalytic induction: Subverting specificity in hedgehog protein autoprocessing with small molecules. Methods in Enzymology. 685: 1-41. PMID 37245899 DOI: 10.1016/bs.mie.2023.03.001 |
0.705 |
|
2022 |
Ciulla DA, Dranchak P, Pezzullo JL, Mancusi RA, Psaras AM, Rai G, Giner JL, Inglese J, Callahan BP. A cell-based bioluminescence reporter assay of human Sonic Hedgehog protein autoprocessing to identify inhibitors and activators. The Journal of Biological Chemistry. 102705. PMID 36400200 DOI: 10.1016/j.jbc.2022.102705 |
0.693 |
|
2020 |
Callahan BP, Ciulla DA, Wagner AG, Xu Z, Zhang X. Specificity Distorted: Chemical Induction of Biological Paracatalysis. Biochemistry. PMID 32931253 DOI: 10.1021/acs.biochem.0c00643 |
0.675 |
|
2019 |
Zhao J, Ciulla DA, Xie J, Castillo DA, Wagner A, Zwarycz AS, Lin Z, Beadle S, Giner JL, Li Z, Li H, Banavali N, Callahan BP, Wang C. General Base Swap Preserves Activity and Expands Substrate Tolerance in Hedgehog Autoprocessing. Journal of the American Chemical Society. PMID 31682419 DOI: 10.1021/Jacs.9B08914 |
0.692 |
|
2019 |
Zhang X, Xu Z, Moumin DS, Ciulla DA, Owen TS, Mancusi RA, Giner JL, Wang C, Callahan BP. Protein-Nucleic Acid Conjugation with Sterol Linkers Using Hedgehog Autoprocessing. Bioconjugate Chemistry. PMID 31600061 DOI: 10.1021/Acs.Bioconjchem.9B00550 |
0.666 |
|
2019 |
Ciulla DA, Wagner AG, Liu X, Cooper CL, Jorgensen MT, Wang C, Goyal P, Banavali NK, Pezzullo JL, Giner JL, Callahan BP. Sterol A-ring plasticity in hedgehog protein cholesterolysis supports a primitive substrate selectivity mechanism. Chemical Communications (Cambridge, England). PMID 30672911 DOI: 10.1039/C8Cc09729A |
0.677 |
|
2017 |
Ciulla D, Jorgensen M, Giner JL, Callahan BP. Chemical bypass of general base catalysis in hedgehog protein cholesterolysis using a hyper-nucleophilic substrate. Journal of the American Chemical Society. PMID 28930454 DOI: 10.1021/jacs.7b05161 |
0.685 |
|
2016 |
Bordeau BM, Ciulla DA, Callahan BP. Hedgehog Proteins Consume Steroidal CYP17A1 Antagonists: Potential Therapeutic Significance in Advanced Prostate Cancer. Chemmedchem. PMID 27435344 DOI: 10.1002/cmdc.201600238 |
0.633 |
|
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