Pierre Vanderhaeghen - Publications

University of Brussels ULB, Bruxelles, Bruxelles, Belgium 
Evolution and devlopment of cerebral cortex

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Bonnefont J, Tiberi L, van den Ameele J, Potier D, Gaber ZB, Lin X, Bilheu A, Herpoel A, Velez Bravo FD, Guillemot F, Aerts S, Vanderhaeghen P. Cortical Neurogenesis Requires Bcl6-Mediated Transcriptional Repression of Multiple Self-Renewal-Promoting Extrinsic Pathways. Neuron. PMID 31353074 DOI: 10.1016/j.neuron.2019.06.027  0.32
2018 Suzuki IK, Gacquer D, Van Heurck R, Kumar D, Wojno M, Bilheu A, Herpoel A, Lambert N, Cheron J, Polleux F, Detours V, Vanderhaeghen P. Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation. Cell. 173: 1370-1384.e16. PMID 29856955 DOI: 10.1016/j.cell.2018.03.067  0.32
2018 Espuny-Camacho I, Michelsen KA, Linaro D, Bilheu A, Acosta-Verdugo S, Herpoel A, Giugliano M, Gaillard A, Vanderhaeghen P. Human Pluripotent Stem-Cell-Derived Cortical Neurons Integrate Functionally into the Lesioned Adult Murine Visual Cortex in an Area-Specific Way. Cell Reports. 23: 2732-2743. PMID 29847802 DOI: 10.1016/j.celrep.2018.04.094  0.32
2016 Quan XJ, Yuan L, Tiberi L, Claeys A, De Geest N, Yan J, van der Kant R, Xie WR, Klisch TJ, Shymkowitz J, Rousseau F, Bollen M, Beullens M, Zoghbi HY, Vanderhaeghen P, et al. Post-translational Control of the Temporal Dynamics of Transcription Factor Activity Regulates Neurogenesis. Cell. 164: 460-475. PMID 26824657 DOI: 10.1016/j.cell.2015.12.048  1
2015 Brennand KJ, Marchetto MC, Benvenisty N, Brüstle O, Ebert A, Izpisua Belmonte JC, Kaykas A, Lancaster MA, Livesey FJ, McConnell MJ, McKay RD, Morrow EM, Muotri AR, Panchision DM, Rubin LL, ... ... Vanderhaeghen P, et al. Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders. Stem Cell Reports. PMID 26610635 DOI: 10.1016/j.stemcr.2015.10.011  1
2015 Suzuki IK, Vanderhaeghen P. Is this a brain which I see before me? Modeling human neural development with pluripotent stem cells. Development (Cambridge, England). 142: 3138-50. PMID 26395142 DOI: 10.1242/dev.120568  1
2015 Nageshappa S, Carromeu C, Trujillo CA, Mesci P, Espuny-Camacho I, Pasciuto E, Vanderhaeghen P, Verfaillie CM, Raitano S, Kumar A, Carvalho CM, Bagni C, Ramocki MB, Araujo BH, Torres LB, et al. Altered neuronal network and rescue in a human MECP2 duplication model. Molecular Psychiatry. PMID 26347316 DOI: 10.1038/mp.2015.128  1
2015 Michelsen KA, Acosta-Verdugo S, Benoit-Marand M, Espuny-Camacho I, Gaspard N, Saha B, Gaillard A, Vanderhaeghen P. Area-specific reestablishment of damaged circuits in the adult cerebral cortex by cortical neurons derived from mouse embryonic stem cells. Neuron. 85: 982-97. PMID 25741724 DOI: 10.1016/j.neuron.2015.02.001  1
2015 Raitano S, Ordovàs L, De Muynck L, Guo W, Espuny-Camacho I, Geraerts M, Khurana S, Vanuytsel K, Tóth BI, Voets T, Vandenberghe R, Cathomen T, Van Den Bosch L, Vanderhaeghen P, Van Damme P, et al. Restoration of progranulin expression rescues cortical neuron generation in an induced pluripotent stem cell model of frontotemporal dementia. Stem Cell Reports. 4: 16-24. PMID 25556567 DOI: 10.1016/j.stemcr.2014.12.001  1
2014 Tiberi L, Bonnefont J, van den Ameele J, Le Bon SD, Herpoel A, Bilheu A, Baron BW, Vanderhaeghen P. A BCL6/BCOR/SIRT1 complex triggers neurogenesis and suppresses medulloblastoma by repressing Sonic Hedgehog signaling. Cancer Cell. 26: 797-812. PMID 25490446 DOI: 10.1016/j.ccell.2014.10.021  1
2014 Anderson S, Vanderhaeghen P. Cortical neurogenesis from pluripotent stem cells: complexity emerging from simplicity. Current Opinion in Neurobiology. 27: 151-7. PMID 24747604 DOI: 10.1016/j.conb.2014.03.012  1
2014 van den Ameele J, Tiberi L, Vanderhaeghen P, Espuny-Camacho I. Thinking out of the dish: what to learn about cortical development using pluripotent stem cells. Trends in Neurosciences. 37: 334-42. PMID 24745669 DOI: 10.1016/j.tins.2014.03.005  1
2014 Nagashima F, Suzuki IK, Shitamukai A, Sakaguchi H, Iwashita M, Kobayashi T, Tone S, Toida K, Vanderhaeghen P, Kosodo Y. Novel and robust transplantation reveals the acquisition of polarized processes by cortical cells derived from mouse and human pluripotent stem cells. Stem Cells and Development. 23: 2129-42. PMID 24325299 DOI: 10.1089/scd.2013.0251  1
2013 Igoillo-Esteve M, Genin A, Lambert N, Désir J, Pirson I, Abdulkarim B, Simonis N, Drielsma A, Marselli L, Marchetti P, Vanderhaeghen P, Eizirik DL, Wuyts W, Julier C, Chakera AJ, et al. tRNA methyltransferase homolog gene TRMT10A mutation in young onset diabetes and primary microcephaly in humans. Plos Genetics. 9: e1003888. PMID 24204302 DOI: 10.1371/journal.pgen.1003888  1
2013 Dimidschstein J, Passante L, Dufour A, van den Ameele J, Tiberi L, Hrechdakian T, Adams R, Klein R, Lie DC, Jossin Y, Vanderhaeghen P. Ephrin-B1 controls the columnar distribution of cortical pyramidal neurons by restricting their tangential migration. Neuron. 79: 1123-35. PMID 24050402 DOI: 10.1016/j.neuron.2013.07.015  1
2013 Espuny-Camacho I, Michelsen KA, Gall D, Linaro D, Hasche A, Bonnefont J, Bali C, Orduz D, Bilheu A, Herpoel A, Lambert N, Gaspard N, Péron S, Schiffmann SN, Giugliano M, ... ... Vanderhaeghen P, et al. Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo. Neuron. 77: 440-56. PMID 23395372 DOI: 10.1016/j.neuron.2012.12.011  1
2013 Defourny J, Poirrier AL, Lallemend F, Mateo Sánchez S, Neef J, Vanderhaeghen P, Soriano E, Peuckert C, Kullander K, Fritzsch B, Nguyen L, Moonen G, Moser T, Malgrange B. Ephrin-A5/EphA4 signalling controls specific afferent targeting to cochlear hair cells. Nature Communications. 4: 1438. PMID 23385583 DOI: 10.1038/ncomms2445  1
2013 van den Berghe V, Stappers E, Vandesande B, Dimidschstein J, Kroes R, Francis A, Conidi A, Lesage F, Dries R, Cazzola S, Berx G, Kessaris N, Vanderhaeghen P, van Ijcken W, Grosveld FG, et al. Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1. Neuron. 77: 70-82. PMID 23312517 DOI: 10.1016/j.neuron.2012.11.009  1
2012 Vanderhaeghen P. Generation of cortical neurons from pluripotent stem cells. Progress in Brain Research. 201: 183-95. PMID 23186715 DOI: 10.1016/B978-0-444-59544-7.00009-3  1
2012 Tiberi L, van den Ameele J, Dimidschstein J, Piccirilli J, Gall D, Herpoel A, Bilheu A, Bonnefont J, Iacovino M, Kyba M, Bouschet T, Vanderhaeghen P. BCL6 controls neurogenesis through Sirt1-dependent epigenetic repression of selective Notch targets. Nature Neuroscience. 15: 1627-35. PMID 23160044 DOI: 10.1038/nn.3264  1
2012 Seibt J, Armant O, Le Digarcher A, Castro D, Ramesh V, Journot L, Guillemot F, Vanderhaeghen P, Bouschet T. Expression at the imprinted dlk1-gtl2 locus is regulated by proneural genes in the developing telencephalon. Plos One. 7: e48675. PMID 23139813 DOI: 10.1371/journal.pone.0048675  1
2012 Karayiorgou M, Flint J, Gogos JA, Malenka RC. The best of times, the worst of times for psychiatric disease. Nature Neuroscience. 15: 811-2. PMID 22627793 DOI: 10.1038/nn.3115  1
2012 Charrier C, Joshi K, Coutinho-Budd J, Kim JE, Lambert N, de Marchena J, Jin WL, Vanderhaeghen P, Ghosh A, Sassa T, Polleux F. Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation. Cell. 149: 923-35. PMID 22559944 DOI: 10.1016/j.cell.2012.03.034  1
2012 van den Ameele J, Tiberi L, Bondue A, Paulissen C, Herpoel A, Iacovino M, Kyba M, Blanpain C, Vanderhaeghen P. Eomesodermin induces Mesp1 expression and cardiac differentiation from embryonic stem cells in the absence of Activin. Embo Reports. 13: 355-62. PMID 22402664 DOI: 10.1038/embor.2012.23  1
2012 Tiberi L, Vanderhaeghen P, van den Ameele J. Cortical neurogenesis and morphogens: diversity of cues, sources and functions. Current Opinion in Cell Biology. 24: 269-76. PMID 22342580 DOI: 10.1016/j.ceb.2012.01.010  1
2012 Pietri S, Dimidschstein J, Tiberi L, Sotiropoulou PA, Bilheu A, Goffinet A, Achouri Y, Tissir F, Blanpain C, Jacquemin P, Vanderhaeghen P. Transcriptional mechanisms of EphA7 gene expression in the developing cerebral cortex. Cerebral Cortex (New York, N.Y. : 1991). 22: 1678-89. PMID 21940705 DOI: 10.1093/cercor/bhr245  1
2011 Gaspard N, Vanderhaeghen P. Laminar fate specification in the cerebral cortex. F1000 Biology Reports. 3: 6. PMID 21655334 DOI: 10.3410/B3-6  1
2011 Lambert N, Lambot MA, Bilheu A, Albert V, Englert Y, Libert F, Noel JC, Sotiriou C, Holloway AK, Pollard KS, Detours V, Vanderhaeghen P. Genes expressed in specific areas of the human fetal cerebral cortex display distinct patterns of evolution. Plos One. 6: e17753. PMID 21445258 DOI: 10.1371/journal.pone.0017753  1
2011 Gaspard N, Vanderhaeghen P. From stem cells to neural networks: recent advances and perspectives for neurodevelopmental disorders. Developmental Medicine and Child Neurology. 53: 13-7. PMID 21087236 DOI: 10.1111/j.1469-8749.2010.03827.x  1
2010 Vanderhaeghen P, Cheng HJ. Guidance molecules in axon pruning and cell death. Cold Spring Harbor Perspectives in Biology. 2: a001859. PMID 20516131 DOI: 10.1101/cshperspect.a001859  1
2010 Gaspard N, Vanderhaeghen P. Mechanisms of neural specification from embryonic stem cells. Current Opinion in Neurobiology. 20: 37-43. PMID 20080043 DOI: 10.1016/j.conb.2009.12.001  1
2009 Hick AC, van Eyll JM, Cordi S, Forez C, Passante L, Kohara H, Nagasawa T, Vanderhaeghen P, Courtoy PJ, Rousseau GG, Lemaigre FP, Pierreux CE. Mechanism of primitive duct formation in the pancreas and submandibular glands: a role for SDF-1. Bmc Developmental Biology. 9: 66. PMID 20003423 DOI: 10.1186/1471-213X-9-66  1
2009 Gaspard N, Bouschet T, Herpoel A, Naeije G, van den Ameele J, Vanderhaeghen P. Generation of cortical neurons from mouse embryonic stem cells. Nature Protocols. 4: 1454-63. PMID 19798080 DOI: 10.1038/nprot.2009.157  1
2009 Vanderhaeghen P. Wnts blow on NeuroD1 to promote adult neuron production and diversity. Nature Neuroscience. 12: 1079-81. PMID 19710645 DOI: 10.1038/nn0909-1079  1
2009 Gaspard N, Gaillard A, Vanderhaeghen P. Making cortex in a dish: in vitro corticopoiesis from embryonic stem cells. Cell Cycle (Georgetown, Tex.). 8: 2491-6. PMID 19597331  1
2009 Deleu S, Gonzalez-Merino E, Gaspard N, Nguyen TM, Vanderhaeghen P, Lagneaux L, Toungouz M, Englert Y, Devreker F. Human cystic fibrosis embryonic stem cell lines derived on placental mesenchymal stromal cells. Reproductive Biomedicine Online. 18: 704-16. PMID 19549452 DOI: 10.1016/S1472-6483(10)60018-1  1
2009 Lambot MA, Mendive F, Laurent P, Van Schoore G, Noël JC, Vanderhaeghen P, Vassart G. Three-dimensional reconstruction of efferent ducts in wild-type and Lgr4 knock-out mice. Anatomical Record (Hoboken, N.J. : 2007). 292: 595-603. PMID 19301269 DOI: 10.1002/ar.20883  1
2009 Valverde O, Célérier E, Baranyi M, Vanderhaeghen P, Maldonado R, Sperlagh B, Vassart G, Ledent C. GPR3 receptor, a novel actor in the emotional-like responses. Plos One. 4: e4704. PMID 19259266 DOI: 10.1371/journal.pone.0004704  1
2008 Gaspard N, Bouschet T, Hourez R, Dimidschstein J, Naeije G, van den Ameele J, Espuny-Camacho I, Herpoel A, Passante L, Schiffmann SN, Gaillard A, Vanderhaeghen P. An intrinsic mechanism of corticogenesis from embryonic stem cells. Nature. 455: 351-7. PMID 18716623 DOI: 10.1038/nature07287  1
2008 Rosso L, Marques AC, Weier M, Lambert N, Lambot MA, Vanderhaeghen P, Kaessmann H. Birth and rapid subcellular adaptation of a hominoid-specific CDC14 protein. Plos Biology. 6: e140. PMID 18547142 DOI: 10.1371/journal.pbio.0060140  1
2006 Dufour A, Egea J, Kullander K, Klein R, Vanderhaeghen P. Genetic analysis of EphA-dependent signaling mechanisms controlling topographic mapping in vivo. Development (Cambridge, England). 133: 4415-20. PMID 17035292 DOI: 10.1242/dev.02623  1
2006 Pollard KS, Salama SR, Lambert N, Lambot MA, Coppens S, Pedersen JS, Katzman S, King B, Onodera C, Siepel A, Kern AD, Dehay C, Igel H, Ares M, Vanderhaeghen P, et al. An RNA gene expressed during cortical development evolved rapidly in humans. Nature. 443: 167-72. PMID 16915236 DOI: 10.1038/nature05113  1
2006 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG. Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expression Patterns : Gep. 6: 353-9. PMID 16446123 DOI: 10.1016/j.modgep.2005.09.010  1
2005 Depaepe V, Vanderhaeghen P. [Lethal signals controlling brain size]. MéDecine Sciences : M/S. 21: 795-7. PMID 16197889 DOI: 10.1051/medsci/20052110795  1
2005 Egea J, Nissen UV, Dufour A, Sahin M, Greer P, Kullander K, Mrsic-Flogel TD, Greenberg ME, Kiehn O, Vanderhaeghen P, Klein R. Regulation of EphA 4 kinase activity is required for a subset of axon guidance decisions suggesting a key role for receptor clustering in Eph function. Neuron. 47: 515-28. PMID 16102535 DOI: 10.1016/j.neuron.2005.06.029  1
2005 Lambot MA, Depasse F, Noel JC, Vanderhaeghen P. Mapping labels in the human developing visual system and the evolution of binocular vision. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7232-7. PMID 16079405 DOI: 10.1523/JNEUROSCI.0802-05.2005  1
2005 Depaepe V, Suarez-Gonzalez N, Dufour A, Passante L, Gorski JA, Jones KR, Ledent C, Vanderhaeghen P. Ephrin signalling controls brain size by regulating apoptosis of neural progenitors. Nature. 435: 1244-50. PMID 15902206 DOI: 10.1038/nature03651  1
2004 Vanderhaeghen P. [Molecular mechanisms of neuronal connective tissue genesis during the course of cerebral cortex development]. Bulletin Et MéMoires De L'AcadéMie Royale De MéDecine De Belgique. 159: 111-4; discussion 11. PMID 15366735  1
2004 Vanderhaeghen P, Polleux F. Developmental mechanisms patterning thalamocortical projections: intrinsic, extrinsic and in between. Trends in Neurosciences. 27: 384-91. PMID 15219737 DOI: 10.1016/j.tins.2004.05.009  1
2003 Dufour A, Seibt J, Passante L, Depaepe V, Ciossek T, Frisén J, Kullander K, Flanagan JG, Polleux F, Vanderhaeghen P. Area specificity and topography of thalamocortical projections are controlled by ephrin/Eph genes. Neuron. 39: 453-65. PMID 12895420 DOI: 10.1016/S0896-6273(03)00440-9  1
2003 Seibt J, Schuurmans C, Gradwhol G, Dehay C, Vanderhaeghen P, Guillemot F, Polleux F. Neurogenin2 specifies the connectivity of thalamic neurons by controlling axon responsiveness to intermediate target cues. Neuron. 39: 439-52. PMID 12895419 DOI: 10.1016/S0896-6273(03)00435-5  1
2001 Lyckman AW, Jhaveri S, Feldheim DA, Vanderhaeghen P, Flanagan JG, Sur M. Enhanced plasticity of retinothalamic projections in an ephrin-A2/A5 double mutant. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7684-90. PMID 11567058  1
2000 Flanagan JG, Cheng HJ, Feldheim DA, Hattori M, Lu Q, Vanderhaeghen P. Alkaline phosphatase fusions of ligands or receptors as in situ probes for staining of cells, tissues, and embryos. Methods in Enzymology. 327: 19-35. PMID 11044971 DOI: 10.1016/S0076-6879(00)27264-9  1
2000 Prakash N, Vanderhaeghen P, Cohen-Cory S, Frisén J, Flanagan JG, Frostig RD. Malformation of the functional organization of somatosensory cortex in adult ephrin-A5 knock-out mice revealed by in vivo functional imaging. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5841-7. PMID 10908626  1
2000 Vanderhaeghen P, Lu Q, Prakash N, Frisén J, Walsh CA, Frostig RD, Flanagan JG. A mapping label required for normal scale of body representation in the cortex. Nature Neuroscience. 3: 358-65. PMID 10725925 DOI: 10.1038/73929  1
2000 Vanderhaeghen P. Ephrin-A5 gene is required for normal scale body representation | Un gene qui controle l''homunculus' Medecine/Sciences. 16: 850-851.  1
1998 Feldheim DA, Vanderhaeghen P, Hansen MJ, Frisén J, Lu Q, Barbacid M, Flanagan JG. Topographic guidance labels in a sensory projection to the forebrain. Neuron. 21: 1303-13. PMID 9883724 DOI: 10.1016/S0896-6273(00)80650-9  1
1998 Flanagan JG, Vanderhaeghen P. The ephrins and Eph receptors in neural development. Annual Review of Neuroscience. 21: 309-45. PMID 9530499 DOI: 10.1146/annurev.neuro.21.1.309  1
1997 Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M. Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome. Biochemical and Biophysical Research Communications. 237: 283-7. PMID 9268701 DOI: 10.1006/bbrc.1997.7043  1
1997 Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M. Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species. Genomics. 39: 239-46. PMID 9119360 DOI: 10.1006/geno.1996.4490  1
1996 Vanderhaeghen P. Caractérisation de gènes de récepteurs olfactifs exprimés dans la lignée germinale mâle des mammifères Revue Medicale De Bruxelles. 17: 361.  1
1995 Vassart G, Desarnaud F, Duprez L, Eggerickx D, Labbe O, Libert F, Mollereau C, Parma J, Paschke R, Tonacchera M, Vanderhaeghen P, Van Sande J, Dumont J, Parmentier M. The G protein-coupled receptor family and one of its members, the TSH receptor Annals of the New York Academy of Sciences. 766: 23-30. PMID 7486665 DOI: 10.1111/j.1749-6632.1995.tb26645.x  1
1994 Vanderhaeghen P, Schurmans S, Parmentier M, Vassart G. Do spermatozoids have flair? | LES SPERMATOZOIDES ONT-ILS DU NEZ? Medecine/Sciences. 10: 1136-1139.  1
1994 Parmentier M, Vanderhaeghen P, Schurmans S, Libert F, Vassart G. Molecular genetics of olfactory receptors | GENETIQUE MOLECULAIRE DES RECEPTEURS OLFACTIFS Medecine/Sciences. 10: 1083-1090.  1
1993 Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M. Olfactory receptors are displayed on dog mature sperm cells. The Journal of Cell Biology. 123: 1441-52. PMID 8253843  1
1989 Erneux C, Lemos M, Verjans B, Vanderhaeghen P, Delvaux A, Dumont JE. Soluble and particulate Ins(1,4,5)P3/Ins(1,3,4,5)P4 5-phosphatase in bovine brain. European Journal of Biochemistry / Febs. 181: 317-22. PMID 2540972  1
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