Sin C. Chai, Ph.D. - Publications

Affiliations: 
2002 McGill University, Montreal, QC, Canada 
Area:
memory

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Lin W, Yang L, Chai SC, Lu Y, Chen T. Development of CINPA1 analogs as novel and potent inverse agonists of constitutive androstane receptor. European Journal of Medicinal Chemistry. 108: 505-528. PMID 26717202 DOI: 10.1016/J.Ejmech.2015.12.018  0.489
2015 Halim AS, Chai SC, Wan Ismail WF, Wan Azman WS, Mat Saad AZ, Wan Z. Long-term outcome of free fibula osteocutaneous flap and massive allograft in the reconstruction of long bone defect. Journal of Plastic, Reconstructive & Aesthetic Surgery : Jpras. PMID 26420474 DOI: 10.1016/j.bjps.2015.08.013  0.447
2015 Wang YM, Chai SC, Lin W, Chai X, Elias A, Wu J, Ong SS, Pondugula SR, Beard JA, Schuetz EG, Zeng S, Xie W, Chen T. Serine 350 of Human Pregnane X Receptor Is Crucial for Its Heterodimerization with Retinoid X Receptor Alpha and Transactivation of Target Genes in Vitro and in Vivo. Biochemical Pharmacology. PMID 26119819 DOI: 10.1016/J.Bcp.2015.06.018  0.486
2015 Chai SC, Umayaal S, Saad AZ. Successful pregnancy "during" pedicled transverse rectus abdominis musculocutaneous flap for breast reconstruction with normal vaginal delivery. Indian Journal of Plastic Surgery : Official Publication of the Association of Plastic Surgeons of India. 48: 81-4. PMID 25991893 DOI: 10.4103/0970-0358.155276  0.421
2015 Cherian MT, Chai SC, Chen T. Small-molecule modulators of the constitutive androstane receptor. Expert Opinion On Drug Metabolism & Toxicology. 11: 1099-114. PMID 25979168 DOI: 10.1517/17425255.2015.1043887  0.481
2015 Hooshmand S, Kumar A, Zhang JY, Johnson SA, Chai SC, Arjmandi BH. Evidence for anti-inflammatory and antioxidative properties of dried plum polyphenols in macrophage RAW 264.7 cells. Food & Function. 6: 1719-25. PMID 25921826 DOI: 10.1039/C5Fo00173K  0.441
2015 Chai SC, Umayaal S, Saad AZM. Successful pregnancy »during» pedicled transverse rectus abdominis musculocutaneous flap for breast reconstruction with normal vaginal delivery Indian Journal of Plastic Surgery. 48: 81-84. DOI: 10.4103/0970-0358.155276  0.421
2015 Cherian MT, Chai SC, Chen T. Small-molecule modulators of the constitutive androstane receptor Expert Opinion On Drug Metabolism and Toxicology. 11: 1099-1114. DOI: 10.1517/17425255.2015.1043887  0.434
2014 Li PS, Yu TF, He GH, Chen M, Zhou YB, Chai SC, Xu ZS, Ma YZ. Genome-wide analysis of the Hsf family in soybean and functional identification of GmHsf-34 involvement in drought and heat stresses. Bmc Genomics. 15: 1009. PMID 25416131 DOI: 10.1186/1471-2164-15-1009  0.437
2014 Wang YM, Chai SC, Brewer CT, Chen T. Pregnane X receptor and drug-induced liver injury. Expert Opinion On Drug Metabolism & Toxicology. 10: 1521-32. PMID 25252616 DOI: 10.1517/17425255.2014.963555  0.467
2013 Tambyah PA, Sepramaniam S, Mohamed Ali J, Chai SC, Swaminathan P, Armugam A, Jeyaseelan K. microRNAs in circulation are altered in response to influenza A virus infection in humans. Plos One. 8: e76811. PMID 24116168 DOI: 10.1371/journal.pone.0076811  0.436
2013 Wang YM, Lin W, Chai SC, Wu J, Ong SS, Schuetz EG, Chen T. Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1. Toxicology and Applied Pharmacology. 272: 96-107. PMID 23707768 DOI: 10.1016/J.Taap.2013.05.014  0.501
2013 Goktug AN, Chai SC, Chen T. A timetable organizer for the planning and implementation of screenings in manual or semi-automation mode. Journal of Biomolecular Screening. 18: 938-42. PMID 23653394 DOI: 10.1177/1087057113487556  0.447
2012 Chai SC, Hooshmand S, Saadat RL, Payton ME, Brummel-Smith K, Arjmandi BH. Daily apple versus dried plum: impact on cardiovascular disease risk factors in postmenopausal women. Journal of the Academy of Nutrition and Dietetics. 112: 1158-68. PMID 22818725 DOI: 10.1016/J.Jand.2012.05.005  0.455
2012 Chai SC, Armugam A, Strong PN, Jeyaseelan K. Charaterization of bumarsin, a 3-hydroxy-3-methylglutaryl-coenzyme reductase inhibitor from Mesobuthus martensii Karsch venom. Toxicon : Official Journal of the International Society On Toxinology. 60: 272-9. PMID 22575281 DOI: 10.1016/j.toxicon.2012.04.352  0.495
2012 Wang YM, Ong SS, Chai SC, Chen T. Role of CAR and PXR in xenobiotic sensing and metabolism. Expert Opinion On Drug Metabolism & Toxicology. 8: 803-17. PMID 22554043 DOI: 10.1517/17425255.2012.685237  0.467
2011 Wang WL, Chai SC, Ye QZ. Synthesis and biological evaluation of salicylate-based compounds as a novel class of methionine aminopeptidase inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 7151-4. PMID 22001086 DOI: 10.1016/J.Bmcl.2011.09.080  0.507
2011 Zhang Q, Xiao H, Chai SC, Hoang QQ, Lu H. Hydrophilic residues are crucial for ribosomal protein L11 (RPL11) interaction with zinc finger domain of MDM2 and p53 protein activation. The Journal of Biological Chemistry. 286: 38264-74. PMID 21903592 DOI: 10.1074/Jbc.M111.277012  0.468
2011 Cui J, Chai SC, Shelat AA, Guy RK, Chen T. An automated approach to efficiently reformat a large collection of compounds. Current Chemical Genomics. 5: 42-7. PMID 21804905 DOI: 10.2174/1875397301105010042  0.449
2011 Hooshmand S, Chai SC, Saadat RL, Payton ME, Brummel-Smith K, Arjmandi BH. Comparative effects of dried plum and dried apple on bone in postmenopausal women. The British Journal of Nutrition. 106: 923-30. PMID 21736808 DOI: 10.1017/S000711451100119X  0.458
2011 Chai SC, Wang WL, Ding DR, Ye QZ. Growth inhibition of Escherichia coli and methicillin-resistant Staphylococcus aureus by targeting cellular methionine aminopeptidase. European Journal of Medicinal Chemistry. 46: 3537-40. PMID 21575996 DOI: 10.1016/J.Ejmech.2011.04.056  0.49
2011 Chow J, Tan CH, Ong SH, Goh YS, Gan HW, Tan VH, Chai SC. Transradial percutaneous coronary intervention in acute ST elevation myocardial infarction and high-risk patients: experience in a single centre without cardiothoracic surgical backup. Singapore Medical Journal. 52: 257-62. PMID 21552786  0.421
2011 Yuan H, Chai SC, Lam CK, Howard Xu H, Ye QZ. Two methionine aminopeptidases from Acinetobacter baumannii are functional enzymes. Bioorganic & Medicinal Chemistry Letters. 21: 3395-8. PMID 21524572 DOI: 10.1016/J.Bmcl.2011.03.116  0.513
2011 Kuo CS, Chai SC, Chen HH. Mediodorsal nucleus of the thalamus is critical for the expression of memory of methamphetamine-produced conditioned place preference in rats. Neuroscience. 178: 138-46. PMID 21256933 DOI: 10.1016/j.neuroscience.2010.12.021  0.502
2011 Lee JH, Zhang Q, Jo S, Chai SC, Oh M, Im W, Lu H, Lim HS. Novel pyrrolopyrimidine-based α-helix mimetics: cell-permeable inhibitors of protein−protein interactions. Journal of the American Chemical Society. 133: 676-9. PMID 21171592 DOI: 10.1021/Ja108230S  0.471
2011 Chai SC, Arjmandi BH. Vitamin E dose-dependently reduces aortic fatty lesion formation in orchidectomized aged rats. Aging Clinical and Experimental Research. 23: 11-6. PMID 20065626 DOI: 10.1007/Bf03337742  0.47
2010 Chai SC, Kung JC, Shyu BC. Roles of the anterior cingulate cortex and medial thalamus in short-term and long-term aversive information processing. Molecular Pain. 6: 42. PMID 20653941 DOI: 10.1186/1744-8069-6-42  0.475
2010 Chai SC, Ye QZ. A cell-based assay that targets methionine aminopeptidase in a physiologically relevant environment. Bioorganic & Medicinal Chemistry Letters. 20: 2129-32. PMID 20207144 DOI: 10.1016/J.Bmcl.2010.02.052  0.495
2010 Arjmandi BH, Johnson CD, Campbell SC, Hooshmand S, Chai SC, Akhter MP. Combining fructooligosaccharide and dried plum has the greatest effect on restoring bone mineral density among select functional foods and bioactive compounds. Journal of Medicinal Food. 13: 312-9. PMID 20132045 DOI: 10.1089/Jmf.2009.0068  0.464
2010 Lu JP, Chai SC, Ye QZ. Catalysis and inhibition of Mycobacterium tuberculosis methionine aminopeptidase. Journal of Medicinal Chemistry. 53: 1329-37. PMID 20038112 DOI: 10.1021/Jm901624N  0.495
2010 Wang CC, Chai SC, Holahan MR. Effect of stimulus pre-exposure on inhibitory avoidance retrieval-associated changes in the phosphorylated form of the extracellular signal-regulated kinase-1 and -2 (pERK1/2). Neurobiology of Learning and Memory. 93: 66-76. PMID 19698796 DOI: 10.1016/J.Nlm.2009.08.005  0.673
2009 Chai SC, Ye QZ. Analysis of the stoichiometric metal activation of methionine aminopeptidase. Bmc Biochemistry. 10: 32. PMID 20017927 DOI: 10.1186/1471-2091-10-32  0.48
2009 Chai SC, Ye QZ. Metal-mediated inhibition is a viable approach for inhibiting cellular methionine aminopeptidase. Bioorganic & Medicinal Chemistry Letters. 19: 6862-4. PMID 19889537 DOI: 10.1016/J.Bmcl.2009.10.082  0.497
2009 Chai SC, Lu JP, Ye QZ. Determination of binding affinity of metal cofactor to the active site of methionine aminopeptidase based on quantitation of functional enzyme. Analytical Biochemistry. 395: 263-4. PMID 19712663 DOI: 10.1016/J.Ab.2009.07.054  0.476
2009 Wang HC, Wang YC, Huang AC, Chai SC, Wu YS, Wang CC. Roles of corticosterone in formalin-induced conditioned place aversion in rats. Neuroscience Letters. 464: 122-6. PMID 19703521 DOI: 10.1016/J.Neulet.2009.08.053  0.497
2009 Wang WL, Chai SC, Ye QZ. Synthesis and structure-function analysis of Fe(II)-form-selective antibacterial inhibitors of Escherichia coli methionine aminopeptidase. Bioorganic & Medicinal Chemistry Letters. 19: 1080-3. PMID 19167218 DOI: 10.1016/J.Bmcl.2009.01.011  0.498
2008 Chai SC, Wei CI, Brummel-Smith K, Arjmandi BH. The role of vitamin E in reversing bone loss. Aging Clinical and Experimental Research. 20: 521-7. PMID 19179835 DOI: 10.1007/Bf03324879  0.464
2008 Wang WL, Chai SC, Huang M, He HZ, Hurley TD, Ye QZ. Discovery of inhibitors of Escherichia coli methionine aminopeptidase with the Fe(II)-form selectivity and antibacterial activity. Journal of Medicinal Chemistry. 51: 6110-20. PMID 18785729 DOI: 10.1021/Jm8005788  0.519
2008 Chai SC, Wang WL, Ye QZ. FE(II) is the native cofactor for Escherichia coli methionine aminopeptidase. The Journal of Biological Chemistry. 283: 26879-85. PMID 18669631 DOI: 10.1074/Jbc.M804345200  0.515
2008 Devareddy L, Hooshmand S, Collins JK, Lucas EA, Chai SC, Arjmandi BH. Blueberry prevents bone loss in ovariectomized rat model of postmenopausal osteoporosis. The Journal of Nutritional Biochemistry. 19: 694-9. PMID 18328688 DOI: 10.1016/J.Jnutbio.2007.09.004  0.47
2008 Chai SC, Ju T, Dang M, Goldsmith RB, Maroney MJ, Pochapsky TC. Characterization of metal binding in the active sites of acireductone dioxygenase isoforms from Klebsiella ATCC 8724. Biochemistry. 47: 2428-38. PMID 18237192 DOI: 10.1021/Bi7004152  0.502
2008 Tripathi YB, Tripathi P, Korlagunta K, Chai SC, Smith BJ, Arjmandi BH. Role of Sandhika: a polyherbal formulation on MC3T3-E1 osteoblast-like cells. Inflammation. 31: 1-8. PMID 17687634 DOI: 10.1007/S10753-007-9044-0  0.472
2007 Wang HC, Chai SC, Wu YS, Wang CC. Does the medial thalamus play a role in the negative affective component of visceral pain in rats? Neuroscience Letters. 420: 80-4. PMID 17512660 DOI: 10.1016/J.Neulet.2007.04.064  0.469
2006 Ju T, Goldsmith RB, Chai SC, Maroney MJ, Pochapsky SS, Pochapsky TC. One protein, two enzymes revisited: a structural entropy switch interconverts the two isoforms of acireductone dioxygenase. Journal of Molecular Biology. 363: 823-34. PMID 16989860 DOI: 10.1016/J.Jmb.2006.08.060  0.48
2006 Chai SC, Bruyere JR, Maroney MJ. Probes of the catalytic site of cysteine dioxygenase. The Journal of Biological Chemistry. 281: 15774-9. PMID 16611641 DOI: 10.1074/Jbc.M601269200  0.491
2006 Lucas EA, Chen TY, Chai SC, Devareddy L, Juma S, Wei CI, Tripathi YB, Daggy BP, Hwang DF, Arjmandi BH. Effect of vitamin E on lipid parameters in ovariectomized rats. Journal of Medicinal Food. 9: 77-83. PMID 16579732 DOI: 10.1089/Jmf.2006.9.77  0.448
2006 Chai SC, Holahan MR, Shyu BC, Wang CC. Differential patterns of extracellular signal-regulated kinase-1 and -2 phosphorylation in rat limbic brain regions after short-term and long-term inhibitory avoidance learning. Neuroscience. 137: 1321-30. PMID 16326014 DOI: 10.1016/j.neuroscience.2005.10.009  0.655
2005 Chai SC, Wong CW. Dynamic traction and passive mobilization for the rehabilitation of zone II flexor tendon injuries: a modified regime. The Medical Journal of Malaysia. 60: 59-65. PMID 16381286  0.449
2005 Gaskin S, Chai SC, White NM. Inactivation of the dorsal hippocampus does not affect learning during exploration of a novel environment. Hippocampus. 15: 1085-93. PMID 16187330 DOI: 10.1002/hipo.20127  0.642
2005 White NM, Chai SC, Hamdani S. Learning the morphine conditioned cue preference: cue configuration determines effects of lesions. Pharmacology, Biochemistry, and Behavior. 81: 786-96. PMID 16009410 DOI: 10.1016/J.Pbb.2005.06.002  0.664
2005 Chai SC, Jerkins AA, Banik JJ, Shalev I, Pinkham JL, Uden PC, Maroney MJ. Heterologous expression, purification, and characterization of recombinant rat cysteine dioxygenase. The Journal of Biological Chemistry. 280: 9865-9. PMID 15623508 DOI: 10.1074/Jbc.M413733200  0.496
2004 Yu DK, Wu KK, Abdullah AS, Chai SC, Chai SB, Chau KY, Jeong AK, Liu CY, Tam WK, Yu WH, Yam HK. Smoking cessation among Hong Kong Chinese smokers attending hospital as outpatients: impact of doctors' advice, successful quitting and intention to quit. Asia-Pacific Journal of Public Health / Asia-Pacific Academic Consortium For Public Health. 16: 115-20. PMID 15624789 DOI: 10.1177/101053950401600207  0.417
2004 Chai SC, White NM. Effects of fimbria-fornix, hippocampus, and amygdala lesions on discrimination between proximal locations. Behavioral Neuroscience. 118: 770-84. PMID 15301603 DOI: 10.1037/0735-7044.118.4.770  0.637
2004 Siew JP, Khan AM, Tan PT, Koh JL, Seah SH, Koo CY, Chai SC, Armugam A, Brusic V, Jeyaseelan K. Systematic analysis of snake neurotoxins' functional classification using a data warehousing approach. Bioinformatics (Oxford, England). 20: 3466-80. PMID 15271784 DOI: 10.1093/bioinformatics/bth430  0.434
2004 Armugam A, Gong N, Li X, Siew PY, Chai SC, Nair R, Jeyaseelan K. Group IB phospholipase A2 from Pseudonaja textilis. Archives of Biochemistry and Biophysics. 421: 10-20. PMID 14678780 DOI: 10.1016/j.abb.2003.09.045  0.471
2003 Shyu BC, Chai SC, Kung JC, Fan RJ. A quantitative method for assessing of the affective component of the pain: conditioned response associated with CO2 laser-induced nocifensive reaction. Brain Research. Brain Research Protocols. 12: 1-9. PMID 12928039 DOI: 10.1016/S1385-299X(03)00041-2  0.467
2003 Kung JC, Su NM, Fan RJ, Chai SC, Shyu BC. Contribution of the anterior cingulate cortex to laser-pain conditioning in rats. Brain Research. 970: 58-72. PMID 12706248 DOI: 10.1016/S0006-8993(02)04276-2  0.473
1993 Hsiao S, Chen BH, Chai SC. Sensitivity to dopamine blocking in rat licking behavior: function of taste stimuli, response difficulty, and response measures. The Chinese Journal of Physiology. 36: 27-36. PMID 8275796  0.464
1959 CHAO HY, CHAI SC, CHAO CF. [Pneumonia due to Staphylococcus aureus: report of 6 cases]. Zhonghua Nei Ke Za Zhi. 7: 140-2; English abstr. PMID 13652275  0.424
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