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Year Citation  Score
2019 Kobayashi H, Picard LP, Schönegge AM, Bouvier M. Bioluminescence resonance energy transfer-based imaging of protein-protein interactions in living cells. Nature Protocols. 14: 1084-1107. PMID 30911173 DOI: 10.1038/s41596-019-0129-7  0.68
2019 Okeke K, Angers S, Bouvier M, Michel MC. Agonist-induced desensitisation of β -adrenoceptors: where, when and how? British Journal of Pharmacology. PMID 30809805 DOI: 10.1111/bph.14633  1
2018 Wright SC, Cañizal MCA, Benkel T, Simon K, Le Gouill C, Matricon P, Namkung Y, Lukasheva V, König GM, Laporte SA, Carlsson J, Kostenis E, Bouvier M, Schulte G, Hoffmann C. FZD is a Gα-coupled receptor that exhibits the functional hallmarks of prototypical GPCRs. Science Signaling. 11. PMID 30514810 DOI: 10.1126/scisignal.aar5536  0.48
2018 Namkung Y, LeGouill C, Kumar S, Cao Y, Teixeira LB, Lukasheva V, Giubilaro J, Simões SC, Longpré JM, Devost D, Hébert TE, Piñeyro G, Leduc R, Costa-Neto CM, Bouvier M, et al. Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors. Science Signaling. 11. PMID 30514808 DOI: 10.1126/scisignal.aat1631  0.48
2018 Masureel M, Zou Y, Picard LP, van der Westhuizen E, Mahoney JP, Rodrigues JPGLM, Mildorf TJ, Dror RO, Shaw DE, Bouvier M, Pardon E, Steyaert J, Sunahara RK, Weis WI, Zhang C, et al. Publisher Correction: Structural insights into binding specificity, efficacy and bias of a βAR partial agonist. Nature Chemical Biology. PMID 30504785 DOI: 10.1038/s41589-018-0182-5  0.68
2018 Masureel M, Zou Y, Picard LP, van der Westhuizen E, Mahoney JP, Rodrigues JPGLM, Mildorf TJ, Dror RO, Shaw DE, Bouvier M, Pardon E, Steyaert J, Sunahara RK, Weis WI, Zhang C, et al. Structural insights into binding specificity, efficacy and bias of a βAR partial agonist. Nature Chemical Biology. 14: 1059-1066. PMID 30327561 DOI: 10.1038/s41589-018-0145-x  0.68
2018 Picard LP, Schönegge AM, Lohse MJ, Bouvier M. Bioluminescence resonance energy transfer-based biosensors allow monitoring of ligand- and transducer-mediated GPCR conformational changes. Communications Biology. 1: 106. PMID 30271986 DOI: 10.1038/s42003-018-0101-z  0.68
2018 Luttrell LM, Wang J, Plouffe B, Smith JS, Yamani L, Kaur S, Jean-Charles PY, Gauthier C, Lee MH, Pani B, Kim J, Ahn S, Rajagopal S, Reiter E, Bouvier M, et al. Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9. Science Signaling. 11. PMID 30254056 DOI: 10.1126/scisignal.aat7650  0.64
2018 Chaturvedi M, Schilling J, Beautrait A, Bouvier M, Benovic JL, Shukla AK. Emerging Paradigm of Intracellular Targeting of G Protein-Coupled Receptors. Trends in Biochemical Sciences. PMID 29735399 DOI: 10.1016/j.tibs.2018.04.003  0.6
2017 Schönegge AM, Gallion J, Picard LP, Wilkins AD, Le Gouill C, Audet M, Stallaert W, Lohse MJ, Kimmel M, Lichtarge O, Bouvier M. Evolutionary action and structural basis of the allosteric switch controlling β2AR functional selectivity. Nature Communications. 8: 2169. PMID 29255305 DOI: 10.1038/s41467-017-02257-x  0.68
2017 Beautrait A, Paradis JS, Zimmerman B, Giubilaro J, Nikolajev L, Armando S, Kobayashi H, Yamani L, Namkung Y, Heydenreich FM, Khoury E, Audet M, Roux PP, Veprintsev DB, Laporte SA, ... Bouvier M, et al. A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling. Nature Communications. 8: 15054. PMID 28416805 DOI: 10.1038/ncomms15054  0.48
2017 Sokolina K, Kittanakom S, Snider J, Kotlyar M, Maurice P, Gandía J, Benleulmi-Chaachoua A, Tadagaki K, Oishi A, Wong V, Malty RH, Deineko V, Aoki H, Amin S, Yao Z, ... ... Bouvier M, et al. Systematic protein-protein interaction mapping for clinically relevant human GPCRs. Molecular Systems Biology. 13: 918. PMID 28298427  1
2017 Cahill TJ, Thomsen AR, Tarrasch JT, Plouffe B, Nguyen AH, Yang F, Huang LY, Kahsai AW, Bassoni DL, Gavino BJ, Lamerdin JE, Triest S, Shukla AK, Berger B, Little J, ... ... Bouvier M, et al. Distinct conformations of GPCR-β-arrestin complexes mediate desensitization, signaling, and endocytosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28223524 DOI: 10.1073/pnas.1701529114  0.64
2016 Fritzius T, Turecek R, Seddik R, Kobayashi H, Tiao J, Rem PD, Metz M, Kralikova M, Bouvier M, Gassmann M, Bettler B. KCTD hetero-oligomers confer unique kinetic properties on hippocampal GABAB receptor-induced K+-currents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28003345 DOI: 10.1523/JNEUROSCI.2181-16.2016  0.36
2016 Venkatakrishnan AJ, Deupi X, Lebon G, Heydenreich FM, Flock T, Miljus T, Balaji S, Bouvier M, Veprintsev DB, Tate CG, Schertler GF, Babu MM. Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region. Nature. PMID 27525504 DOI: 10.1038/nature19107  1
2016 Thomsen AR, Plouffe B, Cahill TJ, Shukla AK, Tarrasch JT, Dosey AM, Kahsai AW, Strachan RT, Pani B, Mahoney JP, Huang L, Breton B, Heydenreich FM, Sunahara RK, Skiniotis G, ... Bouvier M, et al. GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling. Cell. PMID 27499021 DOI: 10.1016/j.cell.2016.07.004  0.64
2016 Namkung Y, Le Gouill C, Lukashova V, Kobayashi H, Hogue M, Khoury E, Song M, Bouvier M, Laporte SA. Monitoring G protein-coupled receptor and β-arrestin trafficking in live cells using enhanced bystander BRET. Nature Communications. 7: 12178. PMID 27397672 DOI: 10.1038/ncomms12178  0.48
2016 Devost D, Audet N, Zhou C, Kobayashi H, Bonin H, Lukashova V, Le Gouill C, Bouvier M, Hébert TE. Cellular and subcellular context determine outputs from signaling biosensors. Methods in Cell Biology. 132: 319-37. PMID 26928550 DOI: 10.1016/bs.mcb.2015.11.010  1
2016 Lahaie N, Kralikova M, Pr Eacutezeau L, Blahos J, Bouvier M. Post-endocytotic deubiquitination and degradation of the metabotropic γ-aminobutyric acid receptor by the ubiquitin specific protease 14. The Journal of Biological Chemistry. PMID 26817839 DOI: 10.1074/jbc.M115.686907  0.36
2015 Schrage R, Schmitz AL, Gaffal E, Annala S, Kehraus S, Wenzel D, Büllesbach KM, Bald T, Inoue A, Shinjo Y, Galandrin S, Shridhar N, Hesse M, Grundmann M, Merten N, ... ... Bouvier M, et al. The experimental power of FR900359 to study Gq-regulated biological processes. Nature Communications. 6: 10156. PMID 26658454 DOI: 10.1038/ncomms10156  0.6
2015 Paradis JS, Ly S, Blondel-Tepaz É, Galan JA, Beautrait A, Scott MG, Enslen H, Marullo S, Roux PP, Bouvier M. Receptor sequestration in response to β-arrestin-2 phosphorylation by ERK1/2 governs steady-state levels of GPCR cell-surface expression. Proceedings of the National Academy of Sciences of the United States of America. 112: E5160-8. PMID 26324936 DOI: 10.1073/pnas.1508836112  1
2015 Thanawala VJ, Valdez DJ, Joshi R, Forkuo GS, Parra S, Knoll BJ, Bouvier M, Leff P, Bond RA. Beta-blockers have differential effects on the murine asthma phenotype. British Journal of Pharmacology. PMID 26211486 DOI: 10.1111/bph.13253  1
2015 Santos GA, Duarte DA, Parreiras-E-Silva LT, Teixeira FR, Silva-Rocha R, Oliveira EB, Bouvier M, Costa-Neto CM. Comparative analyses of downstream signal transduction targets modulated after activation of the AT1 receptor by two β-arrestin-biased agonists. Frontiers in Pharmacology. 6: 131. PMID 26191004 DOI: 10.3389/fphar.2015.00131  1
2015 Mancini AD, Bertrand G, Vivot K, Carpentier É, Tremblay C, Ghislain J, Bouvier M, Poitout V. β-Arrestin Recruitment and Biased Agonism at Free Fatty Acid Receptor 1. The Journal of Biological Chemistry. 290: 21131-40. PMID 26157145 DOI: 10.1074/jbc.M115.644450  1
2015 Bouvier M, Chneiweiss H, Jordan B, Lagrue G, Ménard J, Teillaud JL, Kroemer G, Moulin AM, Flahault A, Lafanechère L, Maréchal É, Guillemot JC, Gaille M. The 2010 years | Les années 2010 MéDecine Sciences : M/S. 31: 91-111. PMID 26038813 DOI: 10.1051/medsci/201531s1006  1
2015 Peschanski M, Bergeron M, Boué A, Coppens Y, Changeux JP, Corvol P, Lazar P, Kahn A, Bichet DG, Friedlander G, Epelbaum J, Kroemer G, Chneiweiss H, Munnich A, Bouvier M, et al. [In Process Citation]. MéDecine Sciences : M/S. 31: 47-90. PMID 26038812 DOI: 10.1051/medsci/201531s1005  1
2015 van Unen J, Woolard J, Rinken A, Hoffmann C, Hill SJ, Goedhart J, Bruchas MR, Bouvier M, Adjobo-Hermans MJ. A Perspective on Studying G-Protein-Coupled Receptor Signaling with Resonance Energy Transfer Biosensors in Living Organisms. Molecular Pharmacology. 88: 589-95. PMID 25972446 DOI: 10.1124/mol.115.098897  1
2014 Carr R, Du Y, Quoyer J, Panettieri RA, Janz JM, Bouvier M, Kobilka BK, Benovic JL. Development and characterization of pepducins as Gs-biased allosteric agonists. The Journal of Biological Chemistry. 289: 35668-84. PMID 25395624 DOI: 10.1074/jbc.M114.618819  1
2014 Armando S, Quoyer J, Lukashova V, Maiga A, Percherancier Y, Heveker N, Pin JP, Prézeau L, Bouvier M. The chemokine CXC4 and CC2 receptors form homo- and heterooligomers that can engage their signaling G-protein effectors and βarrestin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 4509-23. PMID 25053617 DOI: 10.1096/fj.13-242446  1
2014 Beautrait A, Michalski KR, Lopez TS, Mannix KM, McDonald DJ, Cutter AR, Medina CB, Hebert AM, Francis CJ, Bouvier M, Tesmer JJ, Sterne-Marr R. Mapping the putative G protein-coupled receptor (GPCR) docking site on GPCR kinase 2: insights from intact cell phosphorylation and recruitment assays. The Journal of Biological Chemistry. 289: 25262-75. PMID 25049229 DOI: 10.1074/jbc.M114.593178  1
2014 Lima-Fernandes E, Misticone S, Boularan C, Paradis JS, Enslen H, Roux PP, Bouvier M, Baillie GS, Marullo S, Scott MG. A biosensor to monitor dynamic regulation and function of tumour suppressor PTEN in living cells. Nature Communications. 5: 4431. PMID 25028204 DOI: 10.1038/ncomms5431  1
2014 Ceraudo E, Galanth C, Carpentier E, Banegas-Font I, Schonegge AM, Alvear-Perez R, Iturrioz X, Bouvier M, Llorens-Cortes C. Biased signaling favoring gi over β-arrestin promoted by an apelin fragment lacking the C-terminal phenylalanine. The Journal of Biological Chemistry. 289: 24599-610. PMID 25012663 DOI: 10.1074/jbc.M113.541698  1
2014 Bouvier M, Hébert TE. Rebuttal from Michel Bouvier and Terence E. Hébert. The Journal of Physiology. 592: 2447. PMID 24931946 DOI: 10.1113/jphysiol.2014.274233  1
2014 Bouvier M, Hébert TE. CrossTalk proposal: Weighing the evidence for Class A GPCR dimers, the evidence favours dimers. The Journal of Physiology. 592: 2439-41. PMID 24931944 DOI: 10.1113/jphysiol.2014.272252  1
2014 Lackman JJ, Markkanen PM, Hogue M, Bouvier M, Petäjä-Repo UE. N-Glycan-dependent and -independent quality control of human δ opioid receptor N-terminal variants. The Journal of Biological Chemistry. 289: 17830-42. PMID 24798333 DOI: 10.1074/jbc.M114.566273  1
2014 Thanawala VJ, Forkuo GS, Stallaert W, Leff P, Bouvier M, Bond R. Ligand bias prevents class equality among beta-blockers. Current Opinion in Pharmacology. 16: 50-7. PMID 24681351 DOI: 10.1016/j.coph.2014.03.002  1
2014 Sauvageau E, Rochdi MD, Oueslati M, Hamdan FF, Percherancier Y, Simpson JC, Pepperkok R, Bouvier M. CNIH4 interacts with newly synthesized GPCR and controls their export from the endoplasmic reticulum. Traffic (Copenhagen, Denmark). 15: 383-400. PMID 24405750 DOI: 10.1111/tra.12148  1
2014 van der Westhuizen ET, Breton B, Christopoulos A, Bouvier M. Quantification of ligand bias for clinically relevant β2-adrenergic receptor ligands: implications for drug taxonomy. Molecular Pharmacology. 85: 492-509. PMID 24366668 DOI: 10.1124/mol.113.088880  1
2014 Schann S, Neuville P, Bouvier M. Novel Screening Paradigms for the Identification of Allosteric Modulators and/or Biased Ligands for Challenging G-Protein-Coupled Receptors Annual Reports in Medicinal Chemistry. 49: 285-300. DOI: 10.1016/B978-0-12-800167-7.00018-3  1
2013 Quoyer J, Janz JM, Luo J, Ren Y, Armando S, Lukashova V, Benovic JL, Carlson KE, Hunt SW, Bouvier M. Pepducin targeting the C-X-C chemokine receptor type 4 acts as a biased agonist favoring activation of the inhibitory G protein. Proceedings of the National Academy of Sciences of the United States of America. 110: E5088-97. PMID 24309376 DOI: 10.1073/pnas.1312515110  1
2013 Schann S, Bouvier M, Neuville P. Technology combination to address GPCR allosteric modulator drug-discovery pitfalls. Drug Discovery Today. Technologies. 10: e261-7. PMID 24050277 DOI: 10.1016/j.ddtec.2012.09.008  1
2013 Lavoie H, Thevakumaran N, Gavory G, Li JJ, Padeganeh A, Guiral S, Duchaine J, Mao DY, Bouvier M, Sicheri F, Therrien M. Inhibitors that stabilize a closed RAF kinase domain conformation induce dimerization. Nature Chemical Biology. 9: 428-36. PMID 23685672 DOI: 10.1038/nchembio.1257  1
2013 Bouvier M. Unraveling the structural basis of GPCR activation and inactivation. Nature Structural & Molecular Biology. 20: 539-41. PMID 23649361 DOI: 10.1038/nsmb.2584  1
2013 Samuels ME, Gallo-Payet N, Pinard S, Hasselmann C, Magne F, Patry L, Chouinard L, Schwartzentruber J, René P, Sawyer N, Bouvier M, Djemli A, Delvin E, Huot C, Eugene D, et al. Bioinactive ACTH causing glucocorticoid deficiency. The Journal of Clinical Endocrinology and Metabolism. 98: 736-42. PMID 23293326 DOI: 10.1210/jc.2012-3199  1
2013 Richard-Lalonde M, Nagi K, Audet N, Sleno R, Amraei M, Hogue M, Balboni G, Schiller PW, Bouvier M, Hébert TE, Pineyro G. Conformational dynamics of Kir3.1/Kir3.2 channel activation via δ-opioid receptors. Molecular Pharmacology. 83: 416-28. PMID 23175530 DOI: 10.1124/mol.112.081950  1
2013 van der Westhuizen E, Stallaert W, Murat B, Audet M, Galandrin S, Lagacé M, Bouvier M. Probing the Functional Selectivity of β-adrenergic Receptors Reveals New Signaling Modes and Potential Therapeutic Applications Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 112. DOI: 10.1016/B978-0-12-800044-1.00098-2  1
2012 Bouvier M. [Metaphors, naming and new signaling paradigms by G-protein-coupled receptors]. MéDecine Sciences : M/S. 28: 801-3. PMID 23067405 DOI: 10.1051/medsci/20122810002  1
2012 Audet M, Bouvier M. Restructuring G-protein- coupled receptor activation. Cell. 151: 14-23. PMID 23021212 DOI: 10.1016/j.cell.2012.09.003  1
2012 Carpentier E, Greenbaum LA, Rochdi D, Abrol R, Goddard WA, Bichet DG, Bouvier M. Identification and characterization of an activating F229V substitution in the V2 vasopressin receptor in an infant with NSIAD. Journal of the American Society of Nephrology : Jasn. 23: 1635-40. PMID 22956819 DOI: 10.1681/ASN.2012010077  1
2012 Zimmerman B, Beautrait A, Aguila B, Charles R, Escher E, Claing A, Bouvier M, Laporte SA. Differential β-arrestin-dependent conformational signaling and cellular responses revealed by angiotensin analogs. Science Signaling. 5: ra33. PMID 22534132 DOI: 10.1126/scisignal.2002522  1
2012 Oligny-Longpré G, Corbani M, Zhou J, Hogue M, Guillon G, Bouvier M. Engagement of β-arrestin by transactivated insulin-like growth factor receptor is needed for V2 vasopressin receptor-stimulated ERK1/2 activation. Proceedings of the National Academy of Sciences of the United States of America. 109: E1028-37. PMID 22493236 DOI: 10.1073/pnas.1112422109  1
2012 Stallaert W, Dorn JF, van der Westhuizen E, Audet M, Bouvier M. Impedance responses reveal β₂-adrenergic receptor signaling pluridimensionality and allow classification of ligands with distinct signaling profiles. Plos One. 7: e29420. PMID 22242170 DOI: 10.1371/journal.pone.0029420  1
2012 Leskelä TT, Lackman JJ, Vierimaa MM, Kobayashi H, Bouvier M, Petäjä-Repo UE. Cys-27 variant of human δ-opioid receptor modulates maturation and cell surface delivery of Phe-27 variant via heteromerization. The Journal of Biological Chemistry. 287: 5008-20. PMID 22184124 DOI: 10.1074/jbc.M111.305656  1
2012 Busnelli M, Saulière A, Manning M, Bouvier M, Galés C, Chini B. Functional selective oxytocin-derived agonists discriminate between individual G protein family subtypes. The Journal of Biological Chemistry. 287: 3617-29. PMID 22069312 DOI: 10.1074/jbc.M111.277178  1
2011 Stallaert W, Christopoulos A, Bouvier M. Ligand functional selectivity and quantitative pharmacology at G protein-coupled receptors. Expert Opinion On Drug Discovery. 6: 811-25. PMID 22651124 DOI: 10.1517/17460441.2011.586691  1
2011 Stefan E, Malleshaiah MK, Breton B, Ear PH, Bachmann V, Beyermann M, Bouvier M, Michnick SW. PKA regulatory subunits mediate synergy among conserved G-protein-coupled receptor cascades. Nature Communications. 2: 598. PMID 22186894 DOI: 10.1038/ncomms1605  1
2011 Yagi H, Tan W, Dillenburg-Pilla P, Armando S, Amornphimoltham P, Simaan M, Weigert R, Molinolo AA, Bouvier M, Gutkind JS. A synthetic biology approach reveals a CXCR4-G13-Rho signaling axis driving transendothelial migration of metastatic breast cancer cells. Science Signaling. 4: ra60. PMID 21934106 DOI: 10.1126/scisignal.2002221  1
2011 Dimond P, Carlson K, Bouvier M, Gerard C, Xu L, Covic L, Agarwal A, Ernst OP, Janz JM, Schwartz TW, Gardella TJ, Milligan G, Kuliopulos A, Sakmar TP, Hunt SW. G protein-coupled receptor modulation with pepducins: moving closer to the clinic. Annals of the New York Academy of Sciences. 1226: 34-49. PMID 21615752 DOI: 10.1111/j.1749-6632.2011.06039.x  1
2011 Ramachandran R, Mihara K, Chung H, Renaux B, Lau CS, Muruve DA, DeFea KA, Bouvier M, Hollenberg MD. Neutrophil elastase acts as a biased agonist for proteinase-activated receptor-2 (PAR2). The Journal of Biological Chemistry. 286: 24638-48. PMID 21576245 DOI: 10.1074/jbc.M110.201988  1
2011 Fulton S, Thibault D, Mendez JA, Lahaie N, Tirotta E, Borrelli E, Bouvier M, Tempel BL, Trudeau LE. Contribution of Kv1.2 voltage-gated potassium channel to D2 autoreceptor regulation of axonal dopamine overflow. The Journal of Biological Chemistry. 286: 9360-72. PMID 21233214 DOI: 10.1074/jbc.M110.153262  1
2011 Bouvier M, Chneiweiss H. Médecine/sciences 2011 | Médecine/sciences 2011 Medecine/Sciences. 27: 3-4. DOI: 10.1051/medsci/20112713  1
2010 Breton B, Sauvageau É, Zhou J, Bonin H, Le Gouill C, Bouvier M. Multiplexing of multicolor bioluminescence resonance energy transfer. Biophysical Journal. 99: 4037-46. PMID 21156147 DOI: 10.1016/j.bpj.2010.10.025  1
2010 Patel M, Margaron Y, Fradet N, Yang Q, Wilkes B, Bouvier M, Hofmann K, Côté JF. An evolutionarily conserved autoinhibitory molecular switch in ELMO proteins regulates Rac signaling. Current Biology : Cb. 20: 2021-7. PMID 21035343 DOI: 10.1016/j.cub.2010.10.028  1
2010 René P, Le Gouill C, Pogozheva ID, Lee G, Mosberg HI, Farooqi IS, Valenzano KJ, Bouvier M. Pharmacological chaperones restore function to MC4R mutants responsible for severe early-onset obesity. The Journal of Pharmacology and Experimental Therapeutics. 335: 520-32. PMID 20826565 DOI: 10.1124/jpet.110.172098  1
2010 Oner SS, An N, Vural A, Breton B, Bouvier M, Blumer JB, Lanier SM. Regulation of the AGS3·G{alpha}i signaling complex by a seven-transmembrane span receptor. The Journal of Biological Chemistry. 285: 33949-58. PMID 20716524 DOI: 10.1074/jbc.M110.138073  1
2010 Breton B, Lagacé M, Bouvier M. Combining resonance energy transfer methods reveals a complex between the alpha2A-adrenergic receptor, Galphai1beta1gamma2, and GRK2. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 4733-43. PMID 20696855 DOI: 10.1096/fj.10-164061  1
2010 Goupil E, Tassy D, Bourguet C, Quiniou C, Wisehart V, Pétrin D, Le Gouill C, Devost D, Zingg HH, Bouvier M, Saragovi HU, Chemtob S, Lubell WD, Claing A, Hébert TE, et al. A novel biased allosteric compound inhibitor of parturition selectively impedes the prostaglandin F2alpha-mediated Rho/ROCK signaling pathway. The Journal of Biological Chemistry. 285: 25624-36. PMID 20551320 DOI: 10.1074/jbc.M110.115196  1
2010 Khelashvili G, Dorff K, Shan J, Camacho-Artacho M, Skrabanek L, Vroling B, Bouvier M, Devi LA, George SR, Javitch JA, Lohse MJ, Milligan G, Neubig RR, Palczewski K, Parmentier M, et al. GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base. Bioinformatics (Oxford, England). 26: 1804-5. PMID 20501551 DOI: 10.1093/bioinformatics/btq264  1
2010 Oner SS, Maher EM, Breton B, Bouvier M, Blumer JB. Receptor-regulated interaction of activator of G-protein signaling-4 and Galphai. The Journal of Biological Chemistry. 285: 20588-94. PMID 20452976 DOI: 10.1074/jbc.C109.088070  1
2010 Solinski HJ, Boekhoff I, Bouvier M, Gudermann T, Breit A. Sensory neuron-specific MAS-related gene-X1 receptors resist agonist-promoted endocytosis. Molecular Pharmacology. 78: 249-59. PMID 20424127 DOI: 10.1124/mol.110.063867  1
2010 Audet M, Lagacé M, Silversides DW, Bouvier M. Protein-protein interactions monitored in cells from transgenic mice using bioluminescence resonance energy transfer. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2829-38. PMID 20335229 DOI: 10.1096/fj.09-144816  1
2010 Rochdi MD, Vargas GA, Carpentier E, Oligny-Longpré G, Chen S, Kovoor A, Gitelman SE, Rosenthal SM, von Zastrow M, Bouvier M. Functional characterization of vasopressin type 2 receptor substitutions (R137H/C/L) leading to nephrogenic diabetes insipidus and nephrogenic syndrome of inappropriate antidiuresis: implications for treatments. Molecular Pharmacology. 77: 836-45. PMID 20159941 DOI: 10.1124/mol.109.061804  1
2010 Bouvier M, Chneiweiss H. [Hopes and challenges in biomedical research]. MéDecine Sciences : M/S. 26: 3-4. PMID 20132760 DOI: 10.1051/medsci/20102613  1
2010 Martel C, Dugré-Brisson S, Boulay K, Breton B, Lapointe G, Armando S, Trépanier V, Duchaîne T, Bouvier M, Desgroseillers L. Multimerization of Staufen1 in live cells. Rna (New York, N.Y.). 16: 585-97. PMID 20075165 DOI: 10.1261/rna.1664210  1
2010 Busillo JM, Armando S, Sengupta R, Meucci O, Bouvier M, Benovic JL. Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling. The Journal of Biological Chemistry. 285: 7805-17. PMID 20048153 DOI: 10.1074/jbc.M109.091173  1
2010 Bockenhauer D, Carpentier E, Rochdi D, van't Hoff W, Breton B, Bernier V, Bouvier M, Bichet DG. Vasopressin type 2 receptor V88M mutation: molecular basis of partial and complete nephrogenic diabetes insipidus. Nephron. Physiology. 114: p1-10. PMID 19816050 DOI: 10.1159/000245059  1
2010 Valenzano KJ, Benjamin ER, René P, Bouvier M. Pharmacological Chaperones: Potential for the Treatment of Hereditary Diseases Caused by Mutations in G Protein-Coupled Receptors Gpcr Molecular Pharmacology and Drug Targeting: Shifting Paradigms and New Directions. 460-510. DOI: 10.1002/9780470627327.ch17  1
2009 Rihakova L, Quiniou C, Hamdan FF, Kaul R, Brault S, Hou X, Lahaie I, Sapieha P, Hamel D, Shao Z, Gobeil F, Hardy P, Joyal JS, Nedev H, Duhamel F, ... ... Bouvier M, et al. VRQ397 (CRAVKY): a novel noncompetitive V2 receptor antagonist. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 297: R1009-18. PMID 19641130 DOI: 10.1152/ajpregu.90766.2008  1
2009 Ramachandran R, Mihara K, Mathur M, Rochdi MD, Bouvier M, Defea K, Hollenberg MD. Agonist-biased signaling via proteinase activated receptor-2: differential activation of calcium and mitogen-activated protein kinase pathways. Molecular Pharmacology. 76: 791-801. PMID 19605524 DOI: 10.1124/mol.109.055509  1
2009 Leduc M, Breton B, Galés C, Le Gouill C, Bouvier M, Chemtob S, Heveker N. Functional selectivity of natural and synthetic prostaglandin EP4 receptor ligands. The Journal of Pharmacology and Experimental Therapeutics. 331: 297-307. PMID 19584306 DOI: 10.1124/jpet.109.156398  1
2009 Kobayashi H, Ogawa K, Yao R, Lichtarge O, Bouvier M. Functional rescue of beta-adrenoceptor dimerization and trafficking by pharmacological chaperones. Traffic (Copenhagen, Denmark). 10: 1019-33. PMID 19515093 DOI: 10.1111/j.1600-0854.2009.00932.x  1
2009 Ferré S, Baler R, Bouvier M, Caron MG, Devi LA, Durroux T, Fuxe K, George SR, Javitch JA, Lohse MJ, Mackie K, Milligan G, Pfleger KD, Pin JP, Volkow ND, et al. Building a new conceptual framework for receptor heteromers. Nature Chemical Biology. 5: 131-4. PMID 19219011 DOI: 10.1038/nchembio0309-131  1
2009 Chneiweiss H, Bouvier M. [Médecine/Sciences as time goes by]. MéDecine Sciences : M/S. 25: 3-4. PMID 19154680 DOI: 10.1051/medsci/20092513  1
2008 Matsubayashi J, Takanashi M, Oikawa K, Fujita K, Tanaka M, Xu M, De Blasi A, Bouvier M, Kinoshita M, Kuroda M, Mukai K. Expression of G protein-coupled receptor kinase 4 is associated with breast cancer tumourigenesis. The Journal of Pathology. 216: 317-27. PMID 18767025 DOI: 10.1002/path.2414  1
2008 Pontier SM, Percherancier Y, Galandrin S, Breit A, Galés C, Bouvier M. Cholesterol-dependent separation of the beta2-adrenergic receptor from its partners determines signaling efficacy: insight into nanoscale organization of signal transduction. The Journal of Biological Chemistry. 283: 24659-72. PMID 18566454 DOI: 10.1074/jbc.M800778200  1
2008 Audet M, Bouvier M. Insights into signaling from the beta2-adrenergic receptor structure. Nature Chemical Biology. 4: 397-403. PMID 18560432 DOI: 10.1038/nchembio.97  1
2008 Galandrin S, Oligny-Longpré G, Bonin H, Ogawa K, Galés C, Bouvier M. Conformational rearrangements and signaling cascades involved in ligand-biased mitogen-activated protein kinase signaling through the beta1-adrenergic receptor. Molecular Pharmacology. 74: 162-72. PMID 18403719 DOI: 10.1124/mol.107.043893  1
2008 Audet N, Galés C, Archer-Lahlou E, Vallières M, Schiller PW, Bouvier M, Pineyro G. Bioluminescence resonance energy transfer assays reveal ligand-specific conformational changes within preformed signaling complexes containing delta-opioid receptors and heterotrimeric G proteins. The Journal of Biological Chemistry. 283: 15078-88. PMID 18381293 DOI: 10.1074/jbc.M707941200  1
2008 Ouedraogo M, Lecat S, Rochdi MD, Hachet-Haas M, Matthes H, Gicquiaux H, Verrier S, Gaire M, Glasser N, Mély Y, Takeda K, Bouvier M, Galzi JL, Bucher B. Distinct motifs of neuropeptide Y receptors differentially regulate trafficking and desensitization. Traffic (Copenhagen, Denmark). 9: 305-24. PMID 18088318 DOI: 10.1111/j.1600-0854.2007.00691.x  1
2008 Coulon V, Audet M, Homburger V, Bockaert J, Fagni L, Bouvier M, Perroy J. Subcellular imaging of dynamic protein interactions by bioluminescence resonance energy transfer. Biophysical Journal. 94: 1001-9. PMID 17921204 DOI: 10.1529/biophysj.107.117275  1
2007 Galés C, Bouvier M. [New talk between receptor and trimeric G proteins: "an intertwined body dance"]. MéDecine Sciences : M/S. 23: 1031-4. PMID 18021724 DOI: 10.1051/medsci/200723111031  1
2007 Stefan E, Aquin S, Berger N, Landry CR, Nyfeler B, Bouvier M, Michnick SW. Quantification of dynamic protein complexes using Renilla luciferase fragment complementation applied to protein kinase A activities in vivo. Proceedings of the National Academy of Sciences of the United States of America. 104: 16916-21. PMID 17942691 DOI: 10.1073/pnas.0704257104  1
2007 Héroux M, Hogue M, Lemieux S, Bouvier M. Functional calcitonin gene-related peptide receptors are formed by the asymmetric assembly of a calcitonin receptor-like receptor homo-oligomer and a monomer of receptor activity-modifying protein-1. The Journal of Biological Chemistry. 282: 31610-20. PMID 17785463 DOI: 10.1074/jbc.M701790200  1
2007 Hamdan FF, Rochdi MD, Breton B, Fessart D, Michaud DE, Charest PG, Laporte SA, Bouvier M. Unraveling G protein-coupled receptor endocytosis pathways using real-time monitoring of agonist-promoted interaction between beta-arrestins and AP-2. The Journal of Biological Chemistry. 282: 29089-100. PMID 17675294 DOI: 10.1074/jbc.M700577200  1
2007 Galandrin S, Oligny-Longpré G, Bouvier M. The evasive nature of drug efficacy: implications for drug discovery. Trends in Pharmacological Sciences. 28: 423-30. PMID 17659355 DOI: 10.1016/j.tips.2007.06.005  1
2007 Marullo S, Bouvier M. Resonance energy transfer approaches in molecular pharmacology and beyond. Trends in Pharmacological Sciences. 28: 362-5. PMID 17629577 DOI: 10.1016/j.tips.2007.06.007  1
2007 Skrabanek L, Murcia M, Bouvier M, Devi L, George SR, Lohse MJ, Milligan G, Neubig R, Palczewski K, Parmentier M, Pin JP, Vriend G, Javitch JA, Campagne F, Filizola M. Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base. Bmc Bioinformatics. 8: 177. PMID 17537266 DOI: 10.1186/1471-2105-8-177  1
2007 Héroux M, Breton B, Hogue M, Bouvier M. Assembly and signaling of CRLR and RAMP1 complexes assessed by BRET. Biochemistry. 46: 7022-33. PMID 17503773 DOI: 10.1021/bi0622470  1
2007 Fessart D, Simaan M, Zimmerman B, Comeau J, Hamdan FF, Wiseman PW, Bouvier M, Laporte SA. Src-dependent phosphorylation of beta2-adaptin dissociates the beta-arrestin-AP-2 complex. Journal of Cell Science. 120: 1723-32. PMID 17456551 DOI: 10.1242/jcs.03444  1
2007 Bouvier M. When an inhibitor promotes activity. Chemistry & Biology. 14: 241-2. PMID 17379138 DOI: 10.1016/j.chembiol.2007.03.004  1
2007 Bouvier M. [Will academic research rescue the drug discovery crisis?]. MéDecine Sciences : M/S. 23: 227-8. PMID 17349271 DOI: 10.1051/medsci/2007233227  1
2007 Pin JP, Neubig R, Bouvier M, Devi L, Filizola M, Javitch JA, Lohse MJ, Milligan G, Palczewski K, Parmentier M, Spedding M. International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the recognition and nomenclature of G protein-coupled receptor heteromultimers. Pharmacological Reviews. 59: 5-13. PMID 17329545 DOI: 10.1124/pr.59.1.5  1
2007 Boeglin D, Hamdan FF, Melendez RE, Cluzeau J, Laperriere A, Héroux M, Bouvier M, Lubell WD. Calcitonin gene-related peptide analogues with aza and indolizidinone amino acid residues reveal conformational requirements for antagonist activity at the human calcitonin gene-related peptide 1 receptor. Journal of Medicinal Chemistry. 50: 1401-8. PMID 17319653 DOI: 10.1021/jm061343w  1
2007 Bouvier M, Heveker N, Jockers R, Marullo S, Milligan G. BRET analysis of GPCR oligomerization: newer does not mean better. Nature Methods. 4: 3-4; author reply 4. PMID 17195017 DOI: 10.1038/nmeth0107-3  1
2007 Charest PG, Oligny-Longpré G, Bonin H, Azzi M, Bouvier M. The V2 vasopressin receptor stimulates ERK1/2 activity independently of heterotrimeric G protein signalling. Cellular Signalling. 19: 32-41. PMID 16857342 DOI: 10.1016/j.cellsig.2006.05.020  1
2006 Hamdan FF, Percherancier Y, Breton B, Bouvier M. Monitoring protein-protein interactions in living cells by bioluminescence resonance energy transfer (BRET). Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 5.23. PMID 18428639 DOI: 10.1002/0471142301.ns0523s34  1
2006 Galés C, Van Durm JJ, Schaak S, Pontier S, Percherancier Y, Audet M, Paris H, Bouvier M. Probing the activation-promoted structural rearrangements in preassembled receptor-G protein complexes. Nature Structural & Molecular Biology. 13: 778-86. PMID 16906158 DOI: 10.1038/nsmb1134  1
2006 Galandrin S, Bouvier M. Distinct signaling profiles of beta1 and beta2 adrenergic receptor ligands toward adenylyl cyclase and mitogen-activated protein kinase reveals the pluridimensionality of efficacy. Molecular Pharmacology. 70: 1575-84. PMID 16901982 DOI: 10.1124/mol.106.026716  1
2006 Rebois RV, Robitaille M, Galés C, Dupré DJ, Baragli A, Trieu P, Ethier N, Bouvier M, Hébert TE. Heterotrimeric G proteins form stable complexes with adenylyl cyclase and Kir3.1 channels in living cells. Journal of Cell Science. 119: 2807-18. PMID 16787947 DOI: 10.1242/jcs.03021  1
2006 Pontier SM, Lahaie N, Ginham R, St-Gelais F, Bonin H, Bell DJ, Flynn H, Trudeau LE, McIlhinney J, White JH, Bouvier M. Coordinated action of NSF and PKC regulates GABAB receptor signaling efficacy. The Embo Journal. 25: 2698-709. PMID 16724110 DOI: 10.1038/sj.emboj.7601157  1
2006 Breit A, Gagnidze K, Devi LA, Lagacé M, Bouvier M. Simultaneous activation of the delta opioid receptor (deltaOR)/sensory neuron-specific receptor-4 (SNSR-4) hetero-oligomer by the mixed bivalent agonist bovine adrenal medulla peptide 22 activates SNSR-4 but inhibits deltaOR signaling. Molecular Pharmacology. 70: 686-96. PMID 16682504 DOI: 10.1124/mol.106.022897  1
2006 Petäjä-Repo UE, Hogue M, Leskelä TT, Markkanen PM, Tuusa JT, Bouvier M. Distinct subcellular localization for constitutive and agonist-modulated palmitoylation of the human delta opioid receptor. The Journal of Biological Chemistry. 281: 15780-9. PMID 16595649 DOI: 10.1074/jbc.M602267200  1
2006 Bouvier M, Friedlander G. [To apprehend the complexity of living at the era of the < Omics >]. MéDecine Sciences : M/S. 22: 3-4. PMID 16386206 DOI: 10.1051/medsci/20062213  1
2006 Barbas D, Zappulla JP, Angers S, Bouvier M, Mohamed HA, Byrne JH, Castellucci VF, DesGroseillers L. An aplysia dopamine1-like receptor: molecular and functional characterization. Journal of Neurochemistry. 96: 414-27. PMID 16336222 DOI: 10.1111/j.1471-4159.2005.03561.x  1
2006 Bernier V, Morello JP, Zarruk A, Debrand N, Salahpour A, Lonergan M, Arthus MF, Laperrière A, Brouard R, Bouvier M, Bichet DG. Pharmacologic chaperones as a potential treatment for X-linked nephrogenic diabetes insipidus. Journal of the American Society of Nephrology : Jasn. 17: 232-43. PMID 16319185 DOI: 10.1681/ASN.2005080854  1
2005 Storez H, Scott MG, Issafras H, Burtey A, Benmerah A, Muntaner O, Piolot T, Tramier M, Coppey-Moisan M, Bouvier M, Labbé-Jullié C, Marullo S. Homo- and hetero-oligomerization of beta-arrestins in living cells. The Journal of Biological Chemistry. 280: 40210-5. PMID 16199535 DOI: 10.1074/jbc.M508001200  1
2005 Hamdan FF, Audet M, Garneau P, Pelletier J, Bouvier M. High-throughput screening of G protein-coupled receptor antagonists using a bioluminescence resonance energy transfer 1-based beta-arrestin2 recruitment assay. Journal of Biomolecular Screening. 10: 463-75. PMID 16093556 DOI: 10.1177/1087057105275344  1
2005 Zhu WZ, Chakir K, Zhang S, Yang D, Lavoie C, Bouvier M, Hébert TE, Lakatta EG, Cheng H, Xiao RP. Heterodimerization of beta1- and beta2-adrenergic receptor subtypes optimizes beta-adrenergic modulation of cardiac contractility. Circulation Research. 97: 244-51. PMID 16002745 DOI: 10.1161/01.RES.0000176764.38934.86  1
2005 Milligan G, Bouvier M. Methods to monitor the quaternary structure of G protein-coupled receptors. The Febs Journal. 272: 2914-25. PMID 15955052 DOI: 10.1111/j.1742-4658.2005.04731.x  1
2005 Hu K, Clément JF, Abrahamyan L, Strebel K, Bouvier M, Kleiman L, Mouland AJ. A human immunodeficiency virus type 1 protease biosensor assay using bioluminescence resonance energy transfer. Journal of Virological Methods. 128: 93-103. PMID 15951029 DOI: 10.1016/j.jviromet.2005.04.012  1
2005 Galés C, Rebois RV, Hogue M, Trieu P, Breit A, Hébert TE, Bouvier M. Real-time monitoring of receptor and G-protein interactions in living cells. Nature Methods. 2: 177-84. PMID 15782186 DOI: 10.1038/nmeth743  1
2005 Charest PG, Terrillon S, Bouvier M. Monitoring agonist-promoted conformational changes of beta-arrestin in living cells by intramolecular BRET. Embo Reports. 6: 334-40. PMID 15776020 DOI: 10.1038/sj.embor.7400373  1
2005 Bulenger S, Marullo S, Bouvier M. Emerging role of homo- and heterodimerization in G-protein-coupled receptor biosynthesis and maturation. Trends in Pharmacological Sciences. 26: 131-7. PMID 15749158 DOI: 10.1016/j.tips.2005.01.004  0.56
2005 Percherancier Y, Berchiche YA, Slight I, Volkmer-Engert R, Tamamura H, Fujii N, Bouvier M, Heveker N. Bioluminescence resonance energy transfer reveals ligand-induced conformational changes in CXCR4 homo- and heterodimers. The Journal of Biological Chemistry. 280: 9895-903. PMID 15632118 DOI: 10.1074/jbc.M411151200  1
2004 Perroy J, Pontier S, Charest PG, Aubry M, Bouvier M. Real-time monitoring of ubiquitination in living cells by BRET. Nature Methods. 1: 203-8. PMID 15782195 DOI: 10.1038/nmeth722  1
2004 Granier S, Terrillon S, Pascal R, Déméné H, Bouvier M, Guillon G, Mendre C. A cyclic peptide mimicking the third intracellular loop of the V2 vasopressin receptor inhibits signaling through its interaction with receptor dimer and G protein. The Journal of Biological Chemistry. 279: 50904-14. PMID 15452133 DOI: 10.1074/jbc.M405089200  1
2004 Bernier V, Bichet DG, Bouvier M. Pharmacological chaperone action on G-protein-coupled receptors. Current Opinion in Pharmacology. 4: 528-33. PMID 15351360 DOI: 10.1016/j.coph.2004.08.001  0.36
2004 Bernier V, Lagacé M, Bichet DG, Bouvier M. Pharmacological chaperones: potential treatment for conformational diseases. Trends in Endocrinology and Metabolism: Tem. 15: 222-8. PMID 15223052 DOI: 10.1016/j.tem.2004.05.003  0.36
2004 Ferré S, Ciruela F, Canals M, Marcellino D, Burgueno J, Casadó V, Hillion J, Torvinen M, Fanelli F, Benedetti Pd Pd, Goldberg SR, Bouvier M, Fuxe K, Agnati LF, Lluis C, et al. Adenosine A2A-dopamine D2 receptor-receptor heteromers. Targets for neuro-psychiatric disorders. Parkinsonism & Related Disorders. 10: 265-71. PMID 15196504 DOI: 10.1016/j.parkreldis.2004.02.014  1
2004 Bernier V, Lagacé M, Lonergan M, Arthus MF, Bichet DG, Bouvier M. Functional rescue of the constitutively internalized V2 vasopressin receptor mutant R137H by the pharmacological chaperone action of SR49059. Molecular Endocrinology (Baltimore, Md.). 18: 2074-84. PMID 15166253 DOI: 10.1210/me.2004-0080  0.36
2004 Salahpour A, Angers S, Mercier JF, Lagacé M, Marullo S, Bouvier M. Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting. The Journal of Biological Chemistry. 279: 33390-7. PMID 15155738 DOI: 10.1074/jbc.M403363200  1
2004 Breit A, Lagacé M, Bouvier M. Hetero-oligomerization between beta2- and beta3-adrenergic receptors generates a beta-adrenergic signaling unit with distinct functional properties. The Journal of Biological Chemistry. 279: 28756-65. PMID 15123695 DOI: 10.1074/jbc.M313310200  0.68
2004 Canals M, Burgueño J, Marcellino D, Cabello N, Canela EI, Mallol J, Agnati L, Ferré S, Bouvier M, Fuxe K, Ciruela F, Lluis C, Franco R. Homodimerization of adenosine A2A receptors: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer. Journal of Neurochemistry. 88: 726-34. PMID 14720222 DOI: 10.1046/j.1471-4159.2003.02200.x  1
2004 Kaykas A, Yang-Snyder J, Héroux M, Shah KV, Bouvier M, Moon RT. Mutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerization. Nature Cell Biology. 6: 52-8. PMID 14688793 DOI: 10.1038/ncb1081  1
2003 Azzi M, Charest PG, Angers S, Rousseau G, Kohout T, Bouvier M, Piñeyro G. Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors. Proceedings of the National Academy of Sciences of the United States of America. 100: 11406-11. PMID 13679574 DOI: 10.1073/pnas.1936664100  1
2003 Canals M, Marcellino D, Fanelli F, Ciruela F, de Benedetti P, Goldberg SR, Neve K, Fuxe K, Agnati LF, Woods AS, Ferré S, Lluis C, Bouvier M, Franco R. Adenosine A2A-dopamine D2 receptor-receptor heteromerization: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer. The Journal of Biological Chemistry. 278: 46741-9. PMID 12933819 DOI: 10.1074/jbc.M306451200  1
2003 Charest PG, Bouvier M. Palmitoylation of the V2 vasopressin receptor carboxyl tail enhances beta-arrestin recruitment leading to efficient receptor endocytosis and ERK1/2 activation. The Journal of Biological Chemistry. 278: 41541-51. PMID 12900404 DOI: 10.1074/jbc.M306589200  1
2003 Salahpour A, Bonin H, Bhalla S, Petäjä-Repo U, Bouvier M. Biochemical characterization of beta2-adrenergic receptor dimers and oligomers. Biological Chemistry. 384: 117-23. PMID 12674505 DOI: 10.1515/BC.2003.012  1
2003 Terrillon S, Durroux T, Mouillac B, Breit A, Ayoub MA, Taulan M, Jockers R, Barberis C, Bouvier M. Oxytocin and vasopressin V1a and V2 receptors form constitutive homo- and heterodimers during biosynthesis. Molecular Endocrinology (Baltimore, Md.). 17: 677-91. PMID 12554793 DOI: 10.1210/me.2002-0222  0.68
2002 Bertrand L, Parent S, Caron M, Legault M, Joly E, Angers S, Bouvier M, Brown M, Houle B, Ménard L. The BRET2/arrestin assay in stable recombinant cells: a platform to screen for compounds that interact with G protein-coupled receptors (GPCRS). Journal of Receptor and Signal Transduction Research. 22: 533-41. PMID 12503639 DOI: 10.1081/RRS-120014619  1
2002 Mercier JF, Salahpour A, Angers S, Breit A, Bouvier M. Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by bioluminescence resonance energy transfer. The Journal of Biological Chemistry. 277: 44925-31. PMID 12244098 DOI: 10.1074/jbc.M205767200  1
2002 Gaigé S, Abysique A, Bouvier M. Effects of leptin on cat intestinal vagal mechanoreceptors. The Journal of Physiology. 543: 679-89. PMID 12205199  0.01
2002 Lavoie C, Mercier JF, Salahpour A, Umapathy D, Breit A, Villeneuve LR, Zhu WZ, Xiao RP, Lakatta EG, Bouvier M, Hébert TE. Beta 1/beta 2-adrenergic receptor heterodimerization regulates beta 2-adrenergic receptor internalization and ERK signaling efficacy. The Journal of Biological Chemistry. 277: 35402-10. PMID 12140284 DOI: 10.1074/jbc.M204163200  1
2002 Issafras H, Angers S, Bulenger S, Blanpain C, Parmentier M, Labbé-Jullié C, Bouvier M, Marullo S. Constitutive agonist-independent CCR5 oligomerization and antibody-mediated clustering occurring at physiological levels of receptors. The Journal of Biological Chemistry. 277: 34666-73. PMID 12089144 DOI: 10.1074/jbc.M202386200  1
2002 Ayoub MA, Couturier C, Lucas-Meunier E, Angers S, Fossier P, Bouvier M, Jockers R. Monitoring of ligand-independent dimerization and ligand-induced conformational changes of melatonin receptors in living cells by bioluminescence resonance energy transfer. The Journal of Biological Chemistry. 277: 21522-8. PMID 11940583 DOI: 10.1074/jbc.M200729200  1
2002 Petäjä-Repo UE, Hogue M, Bhalla S, Laperrière A, Morello JP, Bouvier M. Ligands act as pharmacological chaperones and increase the efficiency of delta opioid receptor maturation. The Embo Journal. 21: 1628-37. PMID 11927547 DOI: 10.1093/emboj/21.7.1628  1
2002 Barbas D, Zappulla JP, Angers S, Bouvier M, Castellucci VF, DesGroseillers L. Functional characterization of a novel serotonin receptor (5-HTap2) expressed in the CNS of Aplysia californica. Journal of Neurochemistry. 80: 335-45. PMID 11902124 DOI: 10.1046/j.0022-3042.2001.00703.x  1
2002 Angers S, Salahpour A, Bouvier M. Dimerization: an emerging concept for G protein-coupled receptor ontogeny and function. Annual Review of Pharmacology and Toxicology. 42: 409-35. PMID 11807178 DOI: 10.1146/annurev.pharmtox.42.091701.082314  1
2001 Carpentier E, Lebesgue D, Kamen AA, Hogue M, Bouvier M, Durocher Y. Increased production of active human beta(2)-adrenergic/G(alphas) fusion receptor in Sf-9 cells using nutrient limiting conditions. Protein Expression and Purification. 23: 66-74. PMID 11570847 DOI: 10.1006/prep.2001.1476  1
2001 Rousseau G, Haddad PS, Gallo-Payet N, Bouvier M. Ca(2+)-dependent sensitization of adenylyl cyclase activity. European Journal of Pharmacology. 422: 53-60. PMID 11430913 DOI: 10.1016/S0014-2999(01)01073-1  1
2001 Morello JP, Salahpour A, Petäjä-Repo UE, Laperrière A, Lonergan M, Arthus MF, Nabi IR, Bichet DG, Bouvier M. Association of calnexin with wild type and mutant AVPR2 that causes nephrogenic diabetes insipidus. Biochemistry. 40: 6766-75. PMID 11389590 DOI: 10.1021/bi002699r  1
2001 Angers S, Salahpour A, Bouvier M. Biochemical and biophysical demonstration of GPCR oligomerization in mammalian cells. Life Sciences. 68: 2243-50. PMID 11358333 DOI: 10.1016/S0024-3205(01)01012-8  1
2001 Moffett S, Rousseau G, Lagacé M, Bouvier M. The palmitoylation state of the beta(2)-adrenergic receptor regulates the synergistic action of cyclic AMP-dependent protein kinase and beta-adrenergic receptor kinase involved in its phosphorylation and desensitization. Journal of Neurochemistry. 76: 269-79. PMID 11146000 DOI: 10.1046/j.1471-4159.2001.00005.x  1
2001 Petaja-Repo UE, Hogue M, Laperriere A, Bhalla S, Walker P, Bouvier M. Newly synthesized human delta opioid receptors retained in the endoplasmic reticulum are retrotranslocated to the cytosol, deglycosylated, ubiquitinated, and degraded by the proteasome. The Journal of Biological Chemistry. 276: 4416-23. PMID 11054417 DOI: 10.1074/jbc.M007151200  1
2000 Morello JP, Petäjä-Repo UE, Bichet DG, Bouvier M. Pharmacological chaperones: a new twist on receptor folding. Trends in Pharmacological Sciences. 21: 466-9. PMID 11121835 DOI: 10.1016/S0165-6147(00)01575-3  1
2000 Angers S, Bouvier M. Reply: beyond receptor dimerization Trends in Pharmacological Sciences. 21: 326. PMID 10973077  1
2000 Salahpour A, Angers S, Bouvier M. Functional significance of oligomerization of G-protein-coupled receptors. Trends in Endocrinology and Metabolism: Tem. 11: 163-8. PMID 10856916 DOI: 10.1016/S1043-2760(00)00260-5  1
2000 Petaja-Repo UE, Hogue M, Laperriere A, Walker P, Bouvier M. Export from the endoplasmic reticulum represents the limiting step in the maturation and cell surface expression of the human delta opioid receptor. The Journal of Biological Chemistry. 275: 13727-36. PMID 10788493 DOI: 10.1074/jbc.275.18.13727  1
2000 Morello JP, Salahpour A, Laperrière A, Bernier V, Arthus MF, Lonergan M, Petäjä-Repo U, Angers S, Morin D, Bichet DG, Bouvier M. Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants. The Journal of Clinical Investigation. 105: 887-95. PMID 10749568 DOI: 10.1172/JCI8688  1
2000 Angers S, Salahpour A, Joly E, Hilairet S, Chelsky D, Dennis M, Bouvier M. Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET). Proceedings of the National Academy of Sciences of the United States of America. 97: 3684-9. PMID 10725388 DOI: 10.1073/pnas.060590697  1
1999 Loisel TP, Ansanay H, Adam L, Marullo S, Seifert R, Lagacé M, Bouvier M. Activation of the beta(2)-adrenergic receptor-Galpha(s) complex leads to rapid depalmitoylation and inhibition of repalmitoylation of both the receptor and Galpha(s). The Journal of Biological Chemistry. 274: 31014-9. PMID 10521499  0.56
1999 Jockers R, Angers S, Da Silva A, Benaroch P, Strosberg AD, Bouvier M, Marullo S. Beta(2)-adrenergic receptor down-regulation. Evidence for a pathway that does not require endocytosis. The Journal of Biological Chemistry. 274: 28900-8. PMID 10506134 DOI: 10.1074/jbc.274.41.28900  1
1998 Bouvier M, Ménard L, Dennis M, Marullo S. Expression and recovery of functional G-protein-coupled receptors using baculovirus expression systems. Current Opinion in Biotechnology. 9: 522-7. PMID 9821283  0.56
1998 Bunnett NW, Bouvier M, De Blasi A. Peptide G protein-coupled receptors meet at Erice. Trends in Pharmacological Sciences. 19: 343-6. PMID 9786019  0.36
1998 Hebert TE, Loisel TP, Adam L, Ethier N, Onge SS, Bouvier M. Functional rescue of a constitutively desensitized beta2AR through receptor dimerization. The Biochemical Journal. 330: 287-93. PMID 9461522  1
1997 Loisel TP, Ansanay H, St-Onge S, Gay B, Boulanger P, Strosberg AD, Marullo S, Bouvier M. Recovery of homogeneous and functional beta 2-adrenergic receptors from extracellular baculovirus particles. Nature Biotechnology. 15: 1300-4. PMID 9359116 DOI: 10.1038/nbt1197-1300  0.56
1997 Murphy RJ, Gardiner PF, Rousseau G, Bouvier M, Béliveau L. Chronic beta-blockade increases skeletal muscle beta-adrenergic-receptor density and enhances contractile force. Journal of Applied Physiology (Bethesda, Md. : 1985). 83: 459-65. PMID 9262441  1
1997 Beaulieu M, Brakier-Gingras L, Bouvier M. Upregulation of alpha1A- and alpha1B-adrenergic receptor mRNAs in the heart of cardiomyopathic hamsters. Journal of Molecular and Cellular Cardiology. 29: 111-9. PMID 9040026 DOI: 10.1006/jmcc.1996.0256  1
1996 Loisel TP, Adam L, Hebert TE, Bouvier M. Agonist stimulation increases the turnover rate of beta 2AR-bound palmitate and promotes receptor depalmitoylation. Biochemistry. 35: 15923-32. PMID 8961959 DOI: 10.1021/bi9611321  1
1996 Morello JP, Bouvier M. Palmitoylation: a post-translational modification that regulates signalling from G-protein coupled receptors. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 74: 449-57. PMID 8960351  1
1996 Ming M, Chan W, Wang TT, Roberts KD, Bouvier M, Lachance S, Carrière S, Chan JS. beta-Adrenoceptors and dexamethasone synergistically stimulate the expression of the angiotensinogen gene in opossum kidney cells. Kidney International. 50: 94-101. PMID 8807577  1
1996 Moffett S, Adam L, Bonin H, Loisel TP, Bouvier M, Mouillac B. Palmitoylated cysteine 341 modulates phosphorylation of the beta2-adrenergic receptor by the cAMP-dependent protein kinase. The Journal of Biological Chemistry. 271: 21490-7. PMID 8702933 DOI: 10.1074/jbc.271.35.21490  1
1996 Hebert TE, Moffett S, Morello JP, Loisel TP, Bichet DG, Barret C, Bouvier M. A peptide derived from a beta2-adrenergic receptor transmembrane domain inhibits both receptor dimerization and activation. The Journal of Biological Chemistry. 271: 16384-92. PMID 8663163 DOI: 10.1074/jbc.271.27.16384  1
1996 Jockers R, Da Silva A, Strosberg AD, Bouvier M, Marullo S. New molecular and structural determinants involved in beta 2-adrenergic receptor desensitization and sequestration. Delineation using chimeric beta 3/beta 2-adrenergic receptors. The Journal of Biological Chemistry. 271: 9355-62. PMID 8621600  0.56
1995 Valiquette M, Parent S, Loisel TP, Bouvier M. Mutation of tyrosine-141 inhibits insulin-promoted tyrosine phosphorylation and increased responsiveness of the human beta 2-adrenergic receptor. The Embo Journal. 14: 5542-9. PMID 8521811  1
1995 Nantel F, Bouvier M, Strosberg AD, Marullo S. Functional effects of long-term activation on human beta 2- and beta 3-adrenoceptor signalling. British Journal of Pharmacology. 114: 1045-51. PMID 7780639  0.56
1995 Marullo S, Nantel F, Strosberg AD, Bouvier M. Variability in the regulation of beta-adrenoceptor subtypes. Biochemical Society Transactions. 23: 126-9. PMID 7758687  0.56
1995 Bouvier M, Moffett S, Loisel TP, Mouillac B, Hebert T, Chidiac P. Palmitoylation of G-protein-coupled receptors: a dynamic modification with functional consequences. Biochemical Society Transactions. 23: 116-20. PMID 7758677  1
1995 Bouvier M, Chidiac P, Hebert TE, Loisel TP, Moffett S, Mouillac B. Dynamic palmitoylation of G-protein-coupled receptors in eukaryotic cells. Methods in Enzymology. 250: 300-14. PMID 7651160 DOI: 10.1016/0076-6879(95)50080-4  1
1995 Varma DR, Deng XF, Chemtob S, Nantel F, Bouvier M. Characterization of the vasorelaxant activity of tyramine and other phenylethylamines in rat aorta. Canadian Journal of Physiology and Pharmacology. 73: 742-6. PMID 7585347  1
1995 Ng GY, Trogadis J, Stevens J, Bouvier M, O'Dowd BF, George SR. Agonist-induced desensitization of dopamine D1 receptor-stimulated adenylyl cyclase activity is temporally and biochemically separated from D1 receptor internalization. Proceedings of the National Academy of Sciences of the United States of America. 92: 10157-61. PMID 7479745 DOI: 10.1073/pnas.92.22.10157  1
1994 Nantel F, Marullo S, Krief S, Strosberg AD, Bouvier M. Cell-specific down-regulation of the beta 3-adrenergic receptor. The Journal of Biological Chemistry. 269: 13148-55. PMID 8175742  0.56
1994 Chidiac P, Hebert TE, Valiquette M, Dennis M, Bouvier M. Inverse agonist activity of beta-adrenergic antagonists. Molecular Pharmacology. 45: 490-9. PMID 7908406  1
1994 St-Onge S, Chidiac P, Brakier-Gingras L, Bouvier M. Beta-adrenergic receptor desensitization in the early stage of hereditary cardiomyopathy in hamsters. Canadian Journal of Physiology and Pharmacology. 72: 875-83. PMID 7834576  1
1994 Ng GY, Mouillac B, George SR, Caron M, Dennis M, Bouvier M, O'Dowd BF. Desensitization, phosphorylation and palmitoylation of the human dopamine D1 receptor. European Journal of Pharmacology. 267: 7-19. PMID 7515822 DOI: 10.1016/0922-4106(94)90219-4  1
1990 Collins S, Bouvier M, Lohse MJ, Benovic JL, Caron MG, Lefkowitz RJ. Mechanisms involved in adrenergic receptor desensitization. Biochemical Society Transactions. 18: 541-4. PMID 2177406  1
1990 Valiquette M, Bonin H, Hnatowich M, Caron MG, Lefkowitz RJ, Bouvier M. Involvement of tyrosine residues located in the carboxyl tail of the human beta 2-adrenergic receptor in agonist-induced down-regulation of the receptor. Proceedings of the National Academy of Sciences of the United States of America. 87: 5089-93. PMID 2164220  0.64
1990 Hausdorff WP, Lohse MJ, Bouvier M, Liggett SB, Caron MG, Lefkowitz RJ. Two kinases mediate agonist-dependent phosphorylation and desensitization of the beta 2-adrenergic receptor. Symposia of the Society For Experimental Biology. 44: 225-40. PMID 1983369  0.68
1989 Liggett SB, Bouvier M, O'Dowd BF, Caron MG, Lefkowitz RJ, DeBlasi A. Substitution of an extracellular cysteine in the beta 2-adrenergic receptor enhances agonist-promoted phosphorylation and receptor desensitization. Biochemical and Biophysical Research Communications. 165: 257-63. PMID 2556136  0.64
1989 Liggett SB, Bouvier M, Hausdorff WP, O'Dowd B, Caron MG, Lefkowitz RJ. Altered patterns of agonist-stimulated cAMP accumulation in cells expressing mutant beta 2-adrenergic receptors lacking phosphorylation sites. Molecular Pharmacology. 36: 641-6. PMID 2554115  0.64
1989 Hausdorff WP, Bouvier M, O'Dowd BF, Irons GP, Caron MG, Lefkowitz RJ. Phosphorylation sites on two domains of the beta 2-adrenergic receptor are involved in distinct pathways of receptor desensitization. The Journal of Biological Chemistry. 264: 12657-65. PMID 2545714  0.64
1989 O'Dowd BF, Hnatowich M, Caron MG, Lefkowitz RJ, Bouvier M. Palmitoylation of the human beta 2-adrenergic receptor. Mutation of Cys341 in the carboxyl tail leads to an uncoupled nonpalmitoylated form of the receptor. The Journal of Biological Chemistry. 264: 7564-9. PMID 2540197  0.64
1989 Bouvier M, Collins S, O'Dowd BF, Campbell PT, de Blasi A, Kobilka BK, MacGregor C, Irons GP, Caron MG, Lefkowitz RJ. Two distinct pathways for cAMP-mediated down-regulation of the beta 2-adrenergic receptor. Phosphorylation of the receptor and regulation of its mRNA level. The Journal of Biological Chemistry. 264: 16786-92. PMID 2476447  1
1989 Collins S, Bouvier M, Bolanowski MA, Caron MG, Lefkowitz RJ. cAMP stimulates transcription of the beta 2-adrenergic receptor gene in response to short-term agonist exposure. Proceedings of the National Academy of Sciences of the United States of America. 86: 4853-7. PMID 2472635  0.64
1988 Lefkowitz RJ, Kobilka BK, Benovic JL, Bouvier M, Cotecchia S, Hausdorff WP, Dohlman HG, Regan JW, Caron MG. Molecular biology of adrenergic receptors. Cold Spring Harbor Symposia On Quantitative Biology. 53: 507-14. PMID 2855490  1
1988 Benovic JL, Bouvier M, Caron MG, Lefkowitz RJ. Regulation of adenylyl cyclase-coupled beta-adrenergic receptors. Annual Review of Cell Biology. 4: 405-28. PMID 2848553 DOI: 10.1146/annurev.cb.04.110188.002201  1
1988 Bouvier M, Hausdorff WP, De Blasi A, O'Dowd BF, Kobilka BK, Caron MG, Lefkowitz RJ. Removal of phosphorylation sites from the beta 2-adrenergic receptor delays onset of agonist-promoted desensitization. Nature. 333: 370-3. PMID 2836733 DOI: 10.1038/333370a0  1
1988 Bouvier M, Hnatowich M, Collins S, Kobilka BK, Deblasi A, Lefkowitz RJ, Caron MG. Expression of a human cDNA encoding the beta 2-adrenergic receptor in Chinese hamster fibroblasts (CHW): functionality and regulation of the expressed receptors. Molecular Pharmacology. 33: 133-9. PMID 2828911  1
1987 Yoshimasa T, Sibley DR, Bouvier M, Lefkowitz RJ, Caron MG. Cross-talk between cellular signalling pathways suggested by phorbol-ester-induced adenylate cyclase phosphorylation. Nature. 327: 67-70. PMID 3033513 DOI: 10.1038/327067a0  1
1987 Bouvier M, Leeb-Lundberg LM, Benovic JL, Caron MG, Lefkowitz RJ. Regulation of adrenergic receptor function by phosphorylation. II. Effects of agonist occupancy on phosphorylation of alpha 1- and beta 2-adrenergic receptors by protein kinase C and the cyclic AMP-dependent protein kinase. The Journal of Biological Chemistry. 262: 3106-13. PMID 3029101  1
1987 Dohlman HG, Bouvier M, Benovic JL, Caron MG, Lefkowitz RJ. The multiple membrane spanning topography of the beta 2-adrenergic receptor. Localization of the sites of binding, glycosylation, and regulatory phosphorylation by limited proteolysis. The Journal of Biological Chemistry. 262: 14282-8. PMID 2821000  1
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