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Alice Y. Yam, Ph.D. - Publications

Affiliations: 
2005 Stanford University, Palo Alto, CA 
Area:
Biology and of Genetics
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20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Abrahams C, Krimm S, Li X, Zhou S, Hanson J, Masikat MR, Bajjuri K, Heibeck T, Kothari D, Yu A, Henningsen R, Tran C, Yin G, Zawada J, Hang J, ... ... Yam A, et al. Abstract NT-090: PRECLINICAL ACTIVITY AND SAFETY OF STRO-002, A NOVEL ADC TARGETING FOLATE RECEPTOR ALPHA FOR OVARIAN AND ENDOMETRIAL CANCER Clinical Cancer Research. 25. DOI: 10.1158/1557-3265.Ovcasymp18-Nt-090  0.338
2018 Abrahams CL, Li X, Embry M, Yu A, Krimm S, Krueger S, Greenland NY, Wen KW, Jones C, DeAlmeida V, Solis WA, Matheny S, Kline T, Yam AY, Stafford R, et al. Targeting CD74 in multiple myeloma with the novel, site-specific antibody-drug conjugate STRO-001. Oncotarget. 9: 37700-37714. PMID 30701025 DOI: 10.18632/Oncotarget.26491  0.351
2018 Li X, Abrahams C, Zhou S, Krimm S, Henningsen R, Stephenson H, Hanson J, Masikat MR, Bajjuri K, Heibeck T, Tran C, Yin G, Zawada J, Sarma G, Chen J, ... ... Yam A, et al. Abstract 1782: Discovery and activity of STRO-002, a novel ADC targeting folate receptor alpha for ovarian and endometrial cancer Cancer Research. 78: 1782-1782. DOI: 10.1158/1538-7445.Am2018-1782  0.332
2017 Yin G, Stephenson HT, Yang J, Li X, Armstrong SM, Heibeck TH, Tran C, Masikat MR, Zhou S, Stafford RL, Yam AY, Lee J, Steiner AR, Gill A, Penta K, et al. RF1 attenuation enables efficient non-natural amino acid incorporation for production of homogeneous antibody drug conjugates. Scientific Reports. 7: 3026. PMID 28596531 DOI: 10.1038/S41598-017-03192-Z  0.344
2017 Yu A, Abrahams C, Embry M, Li X, Zhao S, Henningsen R, DeAlmeida V, Matheny S, Kline T, Yam A, Stafford R, Natkunam Y, Hallam T, Lupher M, Molina A. High Frequency of CD74 Expression in B-Cell Non-Hodgkin's Lymphoma (NHL) and Targeting with SΤRO-001, a Novel Anti-CD74 Antibody Drug Conjugate (ADC) with Potent I n Vitro Cytotoxicty and In Vivo Anti-Tumor Activity Blood. 130: 573-573. DOI: 10.1182/Blood.V130.Suppl_1.573.573  0.344
2017 Embry M, Li X, Yu A, Abrahams C, Greenland NY, Wen KW, Jones C, DeAlmeida V, Krimm S, Krueger S, Matheny S, Kline T, Yam A, Stafford R, Wiita AP, et al. CD74 Is Expressed in Relapsed and Refractory Multiple Myeloma and Can be Targeted with a Novel Anti-CD74 Antibody Drug Conjugate, SΤRO-001 Blood. 130: 4420-4420. DOI: 10.1182/Blood.V130.Suppl_1.4420.4420  0.355
2017 Abrahams C, Li X, DeAlmeida V, Embry M, Yu A, Krim S, Hoffmann H, Zawada J, Bruhns M, Matheny S, Bussell S, Kline T, Yam A, Stafford R, Hallam T, et al. Abstract 67: Characterization and preclinical development of STRO-001, a novel CD74-targeting antibody-drug conjugate (ADC) for the treatment of B-cell malignancies Cancer Research. 77: 67-67. DOI: 10.1158/1538-7445.Am2017-67  0.369
2016 Li X, Abrahams C, Embry M, Yu A, Kahana J, Brown M, Narla RK, Barnes L, Schwartz E, Boylan J, Zawada J, Stephenson H, Bruhns M, Bussell S, Steiner A, ... ... Yam A, et al. Targeting CD74 with Novel Antibody Drug Conjugates (ADCs) for the Treatment of B-Cell Non-Hodgkin's Lymphoma (NHL) Blood. 128: 464-464. DOI: 10.1182/Blood.V128.22.464.464  0.336
2016 Abrahams C, Li X, Yu A, Krimm S, Kahana J, Narla RK, Schwartz E, Boylan J, Hoffmann H, Steiner A, Zawada J, Stephenson H, Bruhns M, DeAlmeida V, Matheny S, ... ... Yam A, et al. Discovery and Preclinical Development of Novel CD74-Targeting Antibody-Drug Conjugates (ADCs) with Significant Activity in Multiple Myeloma (MM) Cell Lines and Xenograft Models Blood. 128: 4465-4465. DOI: 10.1182/Blood.V128.22.4465.4465  0.365
2014 Groff D, Armstrong S, Rivers PJ, Zhang J, Yang J, Green E, Rozzelle J, Liang S, Kittle JD, Steiner AR, Baliga R, Thanos CD, Hallam TJ, Sato AK, Yam AY. Engineering toward a bacterial "endoplasmic reticulum" for the rapid expression of immunoglobulin proteins. Mabs. 6: 671-8. PMID 24517929 DOI: 10.4161/Mabs.28172  0.403
2014 Zimmerman ES, Heibeck TH, Gill A, Li X, Murray CJ, Madlansacay MR, Tran C, Uter NT, Yin G, Rivers PJ, Yam AY, Wang WD, Steiner AR, Bajad SU, Penta K, et al. Production of site-specific antibody-drug conjugates using optimized non-natural amino acids in a cell-free expression system. Bioconjugate Chemistry. 25: 351-61. PMID 24437342 DOI: 10.1021/Bc400490Z  0.354
2012 Margalith I, Suter C, Ballmer B, Schwarz P, Tiberi C, Sonati T, Falsig J, Nyström S, Hammarström P, Aslund A, Nilsson KP, Yam A, Whitters E, Hornemann S, Aguzzi A. Polythiophenes inhibit prion propagation by stabilizing prion protein (PrP) aggregates. The Journal of Biological Chemistry. 287: 18872-87. PMID 22493452 DOI: 10.1074/Jbc.M112.355958  0.358
2011 Yam AY, Wang X, Gao CM, Connolly MD, Zuckermann RN, Bleu T, Hall J, Fedynyshyn JP, Allauzen S, Peretz D, Salisbury CM. A universal method for detection of amyloidogenic misfolded proteins. Biochemistry. 50: 4322-9. PMID 21539296 DOI: 10.1021/Bi200215J  0.394
2010 Yam AY, Gao CM, Wang X, Wu P, Peretz D. The octarepeat region of the prion protein is conformationally altered in PrP(Sc). Plos One. 5: e9316. PMID 20195363 DOI: 10.1371/Journal.Pone.0009316  0.339
2010 Gao CM, Fedynyshyn JP, Magdangal E, Yam A, Blennow K, Wang X, Salisbury CM, Allauzen S. Detection of Abeta oligomers in Alzheimer's disease patient CSF with a novel misfolded protein assay Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1694  0.306
2008 Yam AY, Xia Y, Lin HT, Burlingame A, Gerstein M, Frydman J. Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly made proteins with complex topologies. Nature Structural & Molecular Biology. 15: 1255-62. PMID 19011634 DOI: 10.1038/Nsmb.1515  0.573
2007 Lau AL, Yam AY, Michelitsch MM, Wang X, Gao C, Goodson RJ, Shimizu R, Timoteo G, Hall J, Medina-Selby A, Coit D, McCoin C, Phelps B, Wu P, Hu C, et al. Characterization of prion protein (PrP)-derived peptides that discriminate full-length PrPSc from PrPC. Proceedings of the National Academy of Sciences of the United States of America. 104: 11551-6. PMID 17601775 DOI: 10.1073/Pnas.0704260104  0.348
2006 Albanèse V, Yam AY, Baughman J, Parnot C, Frydman J. Systems analyses reveal two chaperone networks with distinct functions in eukaryotic cells. Cell. 124: 75-88. PMID 16413483 DOI: 10.1016/J.Cell.2005.11.039  0.533
2005 Yam AY, Albanèse V, Lin HT, Frydman J. Hsp110 cooperates with different cytosolic HSP70 systems in a pathway for de novo folding. The Journal of Biological Chemistry. 280: 41252-61. PMID 16219770 DOI: 10.1074/Jbc.M503615200  0.545
2005 Etchells SA, Meyer AS, Yam AY, Roobol A, Miao Y, Shao Y, Carden MJ, Skach WR, Frydman J, Johnson AE. The cotranslational contacts between ribosome-bound nascent polypeptides and the subunits of the hetero-oligomeric chaperonin TRiC probed by photocross-linking. The Journal of Biological Chemistry. 280: 28118-26. PMID 15929940 DOI: 10.1074/Jbc.M504110200  0.536
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