Paul Pfaffinger - Publications

Baylor College of Medicine, Houston, TX 
Potassium Channels

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Jerng HH, Patel JM, Khan TA, Arenkiel BR, Pfaffinger PJ. Light-regulated voltage-gated potassium channels for acute interrogation of channel function in neurons and behavior. Plos One. 16: e0248688. PMID 33755670 DOI: 10.1371/journal.pone.0248688  0.778
2014 Jerng HH, Pfaffinger PJ. Modulatory mechanisms and multiple functions of somatodendritic A-type K (+) channel auxiliary subunits. Frontiers in Cellular Neuroscience. 8: 82. PMID 24723849 DOI: 10.3389/Fncel.2014.00082  0.84
2014 Jerng HH, Pfaffinger PJ. S-glutathionylation of an auxiliary subunit confers redox sensitivity to Kv4 channel inactivation. Plos One. 9: e93315. PMID 24675763 DOI: 10.1371/Journal.Pone.0093315  0.814
2013 Pfaffinger PJ. A conserved pre-block interaction motif regulates potassium channel activation and N-type inactivation. Plos One. 8: e79891. PMID 24236164 DOI: 10.1371/journal.pone.0079891  0.525
2013 Kunjilwar K, Qian Y, Pfaffinger PJ. Functional stoichiometry underlying KChIP regulation of Kv4.2 functional expression. Journal of Neurochemistry. 126: 462-72. PMID 23692269 DOI: 10.1111/Jnc.12309  0.501
2013 Nadin BM, Pfaffinger PJ. A new TASK for Dipeptidyl Peptidase-like Protein 6. Plos One. 8: e60831. PMID 23593319 DOI: 10.1371/journal.pone.0060831  0.824
2012 Jerng HH, Pfaffinger PJ. Incorporation of DPP6a and DPP6K variants in ternary Kv4 channel complex reconstitutes properties of A-type K current in rat cerebellar granule cells. Plos One. 7: e38205. PMID 22675523 DOI: 10.1371/Journal.Pone.0038205  0.852
2012 Jerng HH, Schaefer MK, Pfaffinger PJ. DPP6A Confers Redox Sensitivity to Kv4 Channel Inactivation Biophysical Journal. 102: 133a. DOI: 10.1016/J.Bpj.2011.11.736  0.835
2011 Jerng HH, Pfaffinger PJ. The Cytoplasmic N-Terminal Domain of DPP6K Disrupts KChiP Modulation of Kv4 Channels Biophysical Journal. 100: 98a. DOI: 10.1016/J.Bpj.2010.12.742  0.83
2010 Nadin BM, Pfaffinger PJ. Dipeptidyl peptidase-like protein 6 is required for normal electrophysiological properties of cerebellar granule cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 8551-65. PMID 20573902 DOI: 10.1523/JNEUROSCI.5489-09.2010  0.843
2010 Jerng HH, Pfaffinger PJ. Differential Integration of DPLP Protein Variants Regulates Inactivation Kinetics of Neuronal A-Type Current Biophysical Journal. 98: 523a. DOI: 10.1016/J.Bpj.2009.12.2841  0.841
2009 Jerng HH, Dougherty K, Covarrubias M, Pfaffinger PJ. A novel N-terminal motif of dipeptidyl peptidase-like proteins produces rapid inactivation of KV4.2 channels by a pore-blocking mechanism. Channels (Austin, Tex.). 3: 448-61. PMID 19901547 DOI: 10.4161/Chan.3.6.10216  0.81
2009 Prince-Carter A, Pfaffinger PJ. Multiple intermediate states precede pore block during N-type inactivation of a voltage-gated potassium channel. The Journal of General Physiology. 134: 15-34. PMID 19528261 DOI: 10.1085/jgp.200910219  0.446
2008 Jerng HH, Pfaffinger PJ. Multiple Kv channel-interacting proteins contain an N-terminal transmembrane domain that regulates Kv4 channel trafficking and gating. The Journal of Biological Chemistry. 283: 36046-59. PMID 18957440 DOI: 10.1074/Jbc.M806852200  0.841
2007 Jerng HH, Lauver AD, Pfaffinger PJ. DPP10 splice variants are localized in distinct neuronal populations and act to differentially regulate the inactivation properties of Kv4-based ion channels. Molecular and Cellular Neurosciences. 35: 604-24. PMID 17475505 DOI: 10.1016/J.Mcn.2007.03.008  0.831
2007 Wang G, Strang C, Pfaffinger PJ, Covarrubias M. Zn2+-dependent redox switch in the intracellular T1-T1 interface of a Kv channel. The Journal of Biological Chemistry. 282: 13637-47. PMID 17331952 DOI: 10.1074/jbc.M609182200  0.444
2006 Lauver A, Yuan LL, Jeromin A, Nadin BM, Rodríguez JJ, Davies HA, Stewart MG, Wu GY, Pfaffinger PJ. Manipulating Kv4.2 identifies a specific component of hippocampal pyramidal neuron A-current that depends upon Kv4.2 expression. Journal of Neurochemistry. 99: 1207-23. PMID 17026528 DOI: 10.1111/j.1471-4159.2006.04185.x  0.797
2006 Lu CW, Lin JH, Rajawat YS, Jerng H, Rami TG, Sanchez X, DeFreitas G, Carabello B, DeMayo F, Kearney DL, Miller G, Li H, Pfaffinger PJ, Bowles NE, Khoury DS, et al. Functional and clinical characterization of a mutation in KCNJ2 associated with Andersen-Tawil syndrome. Journal of Medical Genetics. 43: 653-9. PMID 16571646 DOI: 10.1136/Jmg.2006.040816  0.737
2006 Ren Y, Barnwell LF, Alexander JC, Lubin FD, Adelman JP, Pfaffinger PJ, Schrader LA, Anderson AE. Regulation of surface localization of the small conductance Ca2+-activated potassium channel, Sk2, through direct phosphorylation by cAMP-dependent protein kinase. The Journal of Biological Chemistry. 281: 11769-79. PMID 16513649 DOI: 10.1074/Jbc.M513125200  0.501
2006 Baker KA, Hilty C, Peti W, Prince A, Pfaffinger PJ, Wider G, Wüthrich K, Choe S. NMR-derived dynamic aspects of N-type inactivation of a Kv channel suggest a transient interaction with the T1 domain. Biochemistry. 45: 1663-72. PMID 16460013 DOI: 10.1021/Bi0516430  0.4
2006 Yuan LL, Chen X, Kunjilwar K, Pfaffinger P, Johnston D. Acceleration of K+ channel inactivation by MEK inhibitor U0126. American Journal of Physiology. Cell Physiology. 290: C165-71. PMID 16135544 DOI: 10.1152/ajpcell.00206.2005  0.578
2005 Jerng HH, Kunjilwar K, Pfaffinger PJ. Multiprotein assembly of Kv4.2, KChIP3 and DPP10 produces ternary channel complexes with ISA-like properties. The Journal of Physiology. 568: 767-88. PMID 16123112 DOI: 10.1113/Jphysiol.2005.087858  0.852
2005 Wang G, Shahidullah M, Rocha CA, Strang C, Pfaffinger PJ, Covarrubias M. Functionally active t1-t1 interfaces revealed by the accessibility of intracellular thiolate groups in kv4 channels. The Journal of General Physiology. 126: 55-69. PMID 15955876 DOI: 10.1085/jgp.200509288  0.448
2004 Jerng HH, Pfaffinger PJ, Covarrubias M. Molecular physiology and modulation of somatodendritic A-type potassium channels. Molecular and Cellular Neurosciences. 27: 343-69. PMID 15555915 DOI: 10.1016/J.Mcn.2004.06.011  0.825
2004 Kunjilwar K, Strang C, DeRubeis D, Pfaffinger PJ. KChIP3 rescues the functional expression of Shal channel tetramerization mutants. The Journal of Biological Chemistry. 279: 54542-51. PMID 15485870 DOI: 10.1074/jbc.M409721200  0.576
2004 Jerng HH, Qian Y, Pfaffinger PJ. Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10). Biophysical Journal. 87: 2380-96. PMID 15454437 DOI: 10.1529/Biophysj.104.042358  0.837
2004 Zhou W, Qian Y, Kunjilwar K, Pfaffinger PJ, Choe S. Structural insights into the functional interaction of KChIP1 with Shal-type K(+) channels. Neuron. 41: 573-86. PMID 14980206 DOI: 10.1016/S0896-6273(04)00045-5  0.424
2004 Lin J, Rajawat YS, Lu C, Jerng H, Ramie TG, Millers G, Lib H, Lin M, Pfaffinger PJ, Bowles NE, Khoury DS, Towbin JA. O14-03 Functional and clinical characterization of a mutation in KCNJ2 associated with Andersen syndrome International Journal of Cardiology. 97: S44. DOI: 10.1016/S0167-5273(04)80144-X  0.673
2003 Jeromin A, Yuan LL, Frick A, Pfaffinger P, Johnston D. A modified Sindbis vector for prolonged gene expression in neurons. Journal of Neurophysiology. 90: 2741-5. PMID 12853440 DOI: 10.1152/jn.00464.2003  0.454
2003 Nanao MH, Zhou W, Pfaffinger PJ, Choe S. Determining the basis of channel-tetramerization specificity by x-ray crystallography and a sequence-comparison algorithm: Family Values (FamVal). Proceedings of the National Academy of Sciences of the United States of America. 100: 8670-5. PMID 12835418 DOI: 10.1073/Pnas.1432840100  0.301
2003 Strang C, Kunjilwar K, DeRubeis D, Peterson D, Pfaffinger PJ. The role of Zn2+ in Shal voltage-gated potassium channel formation. The Journal of Biological Chemistry. 278: 31361-71. PMID 12754210 DOI: 10.1074/jbc.M304268200  0.452
2002 Schrader LA, Anderson AE, Mayne A, Pfaffinger PJ, Sweatt JD. PKA modulation of Kv4.2-encoded A-type potassium channels requires formation of a supramolecular complex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10123-33. PMID 12451113 DOI: 10.1523/Jneurosci.22-23-10123.2002  0.696
2002 Jahng AW, Strang C, Kaiser D, Pollard T, Pfaffinger P, Choe S. Zinc mediates assembly of the T1 domain of the voltage-gated K channel 4.2. The Journal of Biological Chemistry. 277: 47885-90. PMID 12372826 DOI: 10.1074/Jbc.M208416200  0.515
2002 Choe S, Cushman S, Baker KA, Pfaffinger P. Excitability is mediated by the T1 domain of the voltage-gated potassium channel. Novartis Foundation Symposium. 245: 169-75; discussion 1. PMID 12027006 DOI: 10.1002/0470868759.Ch12  0.544
2001 Strang C, Cushman SJ, DeRubeis D, Peterson D, Pfaffinger PJ. A central role for the T1 domain in voltage-gated potassium channel formation and function. The Journal of Biological Chemistry. 276: 28493-502. PMID 11312262 DOI: 10.1074/jbc.M010540200  0.378
2000 Adams JP, Anderson AE, Varga AW, Dineley KT, Cook RG, Pfaffinger PJ, Sweatt JD. The A-type potassium channel Kv4.2 is a substrate for the mitogen-activated protein kinase ERK. Journal of Neurochemistry. 75: 2277-87. PMID 11080179 DOI: 10.1046/J.1471-4159.2000.0752277.X  0.623
2000 Cushman SJ, Nanao MH, Jahng AW, DeRubeis D, Choe S, Pfaffinger PJ. Voltage dependent activation of potassium channels is coupled to T1 domain structure. Nature Structural Biology. 7: 403-7. PMID 10802739 DOI: 10.1038/75185  0.45
2000 Anderson AE, Adams JP, Qian Y, Cook RG, Pfaffinger PJ, Sweatt JD. Kv4.2 phosphorylation by cyclic AMP-dependent protein kinase. The Journal of Biological Chemistry. 275: 5337-46. PMID 10681507 DOI: 10.1074/Jbc.275.8.5337  0.567
1999 Choe S, Kreusch A, Pfaffinger PJ. Towards the three-dimensional structure of voltage-gated potassium channels. Trends in Biochemical Sciences. 24: 345-9. PMID 10470033 DOI: 10.1016/S0968-0004(99)01440-1  0.578
1999 Sutherland ML, Williams SH, Abedi R, Overbeek PA, Pfaffinger PJ, Noebels JL. Overexpression of a Shaker-type potassium channel in mammalian central nervous system dysregulates native potassium channel gene expression. Proceedings of the National Academy of Sciences of the United States of America. 96: 2451-5. PMID 10051663 DOI: 10.1073/pnas.96.5.2451  0.525
1999 Bixby KA, Nanao MH, Shen NV, Kreusch A, Bellamy H, Pfaffinger PJ, Choe S. Zn2+-binding and molecular determinants of tetramerization in voltage-gated K+ channels. Nature Structural Biology. 6: 38-43. PMID 9886290 DOI: 10.1038/4911  0.415
1998 Kreusch A, Pfaffinger PJ, Stevens CF, Choe S. Crystal structure of the tetramerization domain of the Shaker potassium channel. Nature. 392: 945-8. PMID 9582078 DOI: 10.1038/31978  0.48
1996 Bixby KA, Pfaffinger PJ, Stevens CF, Choe S. Crystallization and preliminary characterization of the tetramerization domain from the potassium channel Kv3.1 Acta Crystallographica Section a Foundations of Crystallography. 52: C166-C166. DOI: 10.1107/S0108767396092604  0.405
1996 Kreusch A, Pfaffinger PJ, Stevens CF, Choe S. Crystallographic study of the tetramerization domain of aShaker-type potassium channel Acta Crystallographica Section a Foundations of Crystallography. 52: C169-C169. DOI: 10.1107/S0108767396092537  0.463
1995 Shen NV, Pfaffinger PJ. Molecular recognition and assembly sequences involved in the subfamily-specific assembly of voltage-gated K+ channel subunit proteins. Neuron. 14: 625-33. PMID 7695909  0.382
1993 Shen NV, Chen X, Boyer MM, Pfaffinger PJ. Deletion analysis of K+ channel assembly. Neuron. 11: 67-76. PMID 8338669 DOI: 10.1016/0896-6273(93)90271-R  0.451
1992 Furukawa Y, Kandel ER, Pfaffinger P. Three types of early transient potassium currents in Aplysia neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 989-1000. PMID 1545247 DOI: 10.1523/Jneurosci.12-03-00989.1992  0.556
1992 Kaang BK, Pfaffinger PJ, Grant SG, Kandel ER, Furukawa Y. Overexpression of an Aplysia shaker K+ channel gene modifies the electrical properties and synaptic efficacy of identified Aplysia neurons. Proceedings of the National Academy of Sciences of the United States of America. 89: 1133-7. PMID 1310540 DOI: 10.1073/Pnas.89.3.1133  0.772
1991 Pfaffinger PJ, Furukawa Y, Zhao B, Dugan D, Kandel ER. Cloning and expression of an Aplysia K+ channel and comparison with native Aplysia K+ currents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 918-27. PMID 2010814 DOI: 10.1523/Jneurosci.11-04-00918.1991  0.703
1990 Bosma MM, Bernheim L, Leibowitz MD, Pfaffinger PJ, Hille B. Modulation of M current in frog sympathetic ganglion cells. Society of General Physiologists Series. 45: 43-59. PMID 2165636  0.62
1988 Pfaffinger P. Muscarine and t-LHRH suppress M-current by activating an IAP-insensitive G-protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 3343-53. PMID 3139847 DOI: 10.1523/Jneurosci.08-09-03343.1988  0.394
1988 Pfaffinger PJ, Leibowitz MD, Subers EM, Nathanson NM, Almers W, Hille B. Agonists that suppress M-current elicit phosphoinositide turnover and Ca2+ transients, but these events do not explain M-current suppression. Neuron. 1: 477-84. PMID 2483099 DOI: 10.1016/0896-6273(88)90178-X  0.46
1985 Pfaffinger PJ, Martin JM, Hunter DD, Nathanson NM, Hille B. GTP-binding proteins couple cardiac muscarinic receptors to a K channel. Nature. 317: 536-8. PMID 2413367 DOI: 10.1038/317536A0  0.664
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