Neil Nathanson - Publications

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
Signal transduction
Website:
http://depts.washington.edu/nathansn/index.html

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Birdsall NJM, Bradley S, Brown DA, Buckley NJ, Challiss RJ, Christopoulos A, Eglen RM, Ehlert F, Felder CC, Hammer R, Kilbinger HJ, Lambrecht G, Langmead C, Mitchelson F, Mutschler E, ... Nathanson NM, et al. Acetylcholine receptors (muscarinic) (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Iuphar/Bps Guide to Pharmacology Cite. 2019. DOI: 10.2218/gtopdb/f2/2019.4  0.364
2018 Carr BJ, Mihara K, Ramachandran R, Saifeddine M, Nathanson NM, Stell WK, Hollenberg MD. Myopia-Inhibiting Concentrations of Muscarinic Receptor Antagonists Block Activation of Alpha2A-Adrenoceptors In Vitro. Investigative Ophthalmology & Visual Science. 59: 2778-2791. PMID 29860464 DOI: 10.1167/Iovs.17-22562  0.333
2015 Kow RL, Cheng EM, Jiang K, Le JH, Stella N, Nathanson NM. Muscarinic M1 receptor and cannabinoid CB1 receptor do not modulate paraoxon-induced seizures. Pharmacology Research & Perspectives. 3: e00100. PMID 25692018 DOI: 10.1002/Prp2.100  0.791
2014 Kow RL, Jiang K, Naydenov AV, Le JH, Stella N, Nathanson NM. Modulation of pilocarpine-induced seizures by cannabinoid receptor 1. Plos One. 9: e95922. PMID 24752144 DOI: 10.1371/Journal.Pone.0095922  0.789
2012 Kow RL, Nathanson NM. Structural biology: Muscarinic receptors become crystal clear. Nature. 482: 480-1. PMID 22358836 DOI: 10.1038/482480A  0.803
2012 Reiner C, Nathanson NM. Muscarinic receptor trafficking. Handbook of Experimental Pharmacology. 61-78. PMID 22222695 DOI: 10.1007/978-3-642-23274-9_4  0.387
2010 Reiner CL, McCullar JS, Kow RL, Le JH, Goodlett DR, Nathanson NM. RACK1 associates with muscarinic receptors and regulates M(2) receptor trafficking. Plos One. 5: e13517. PMID 20976005 DOI: 10.1371/Journal.Pone.0013517  0.826
2010 Maison SF, Liu XP, Vetter DE, Eatock RA, Nathanson NM, Wess J, Liberman MC. Muscarinic signaling in the cochlea: presynaptic and postsynaptic effects on efferent feedback and afferent excitability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6751-62. PMID 20463237 DOI: 10.1523/Jneurosci.5080-09.2010  0.325
2008 Port MD, Laszlo GS, Nathanson NM. Transregulation of leukemia inhibitory [corrected] factor receptor expression and function by growth factors in neuroblastoma cells. Journal of Neurochemistry. 106: 1941-51. PMID 18624908 DOI: 10.1111/J.1471-4159.2008.05535.X  0.794
2008 Reiner C, Nathanson NM. The internalization of the M2 and M4 muscarinic acetylcholine receptors involves distinct subsets of small G-proteins. Life Sciences. 82: 718-27. PMID 18295803 DOI: 10.1016/j.lfs.2008.01.013  0.36
2008 Port MD, Laszlo GS, Nathanson NM. Transregulation of leukemia inhibitory factor receptor expression and function by growth factors in neuroblastoma cells (Journal of Neurochemistry (2008) 106, (1941-1951)) Journal of Neurochemistry. 107: 1470. DOI: 10.1111/J.1471-4159.2008.05635.X  0.788
2007 Port MD, Gibson RM, Nathanson NM. Differential stimulation-induced receptor localization in lipid rafts for interleukin-6 family cytokines signaling through the gp130/leukemia inhibitory factor receptor complex. Journal of Neurochemistry. 101: 782-93. PMID 17448148 DOI: 10.1111/J.1471-4159.2007.04471.X  0.804
2006 Abrams P, Andersson KE, Buccafusco JJ, Chapple C, de Groat WC, Fryer AD, Kay G, Laties A, Nathanson NM, Pasricha PJ, Wein AJ. Muscarinic receptors: their distribution and function in body systems, and the implications for treating overactive bladder. British Journal of Pharmacology. 148: 565-78. PMID 16751797 DOI: 10.1038/Sj.Bjp.0706780  0.38
2005 Iverson HA, Fox D, Nadler LS, Klevit RE, Nathanson NM. Identification and structural determination of the M(3) muscarinic acetylcholine receptor basolateral sorting signal. The Journal of Biological Chemistry. 280: 24568-75. PMID 15870063 DOI: 10.1074/Jbc.M501264200  0.328
2003 Anagnostaras SG, Murphy GG, Hamilton SE, Mitchell SL, Rahnama NP, Nathanson NM, Silva AJ. Selective cognitive dysfunction in acetylcholine M1 muscarinic receptor mutant mice. Nature Neuroscience. 6: 51-8. PMID 12483218 DOI: 10.1038/nn992  0.301
2002 Bartoe JL, Nathanson NM. Independent roles of SOCS-3 and SHP-2 in the regulation of neuronal gene expression by leukemia inhibitory factor. Brain Research. Molecular Brain Research. 107: 108-19. PMID 12425940 DOI: 10.1016/S0169-328X(02)00452-7  0.782
2002 Porter AC, Bymaster FP, DeLapp NW, Yamada M, Wess J, Hamilton SE, Nathanson NM, Felder CC. M1 muscarinic receptor signaling in mouse hippocampus and cortex. Brain Research. 944: 82-9. PMID 12106668 DOI: 10.1016/S0006-8993(02)02721-X  0.386
2001 Berkeley JL, Gomeza J, Wess J, Hamilton SE, Nathanson NM, Levey AI. M1 muscarinic acetylcholine receptors activate extracellular signal-regulated kinase in CA1 pyramidal neurons in mouse hippocampal slices. Molecular and Cellular Neurosciences. 18: 512-24. PMID 11922142 DOI: 10.1006/Mcne.2001.1042  0.331
2001 Felder CC, Porter AC, Skillman TL, Zhang L, Bymaster FP, Nathanson NM, Hamilton SE, Gomeza J, Wess J, McKinzie DL. Elucidating the role of muscarinic receptors in psychosis. Life Sciences. 68: 2605-13. PMID 11392633 DOI: 10.1016/S0024-3205(01)01059-1  0.36
2001 Shapiro MS, Gomeza J, Hamilton SE, Hille B, Loose MD, Nathanson NM, Roche JP, Wess J. Identification of subtypes of muscarinic receptors that regulate Ca2+ and K+ channel activity in sympathetic neurons. Life Sciences. 68: 2481-7. PMID 11392616 DOI: 10.1016/S0024-3205(01)01042-6  0.352
2001 Gillette MU, Buchanan GF, Artinian L, Hamilton SE, Nathanson NM, Liu C. Role of the M1 receptor in regulating circadian rhythms. Life Sciences. 68: 2467-72. PMID 11392614 DOI: 10.1016/S0024-3205(01)01040-2  0.361
2001 Hamilton SE, Nathanson NM. The M1 receptor is required for muscarinic activation of mitogen-activated protein (MAP) kinase in murine cerebral cortical neurons. The Journal of Biological Chemistry. 276: 15850-3. PMID 11278934 DOI: 10.1074/jbc.M011563200  0.351
2000 Belmonte KE, McKinnon LA, Nathanson NM. Developmental expression of muscarinic acetylcholine receptors in chick retina: selective induction of M2 muscarinic receptor expression in ovo by a factor secreted by muller glial cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 8417-25. PMID 11069949  0.34
2000 Schlador ML, Grubbs RD, Nathanson NM. Multiple topological domains mediate subtype-specific internalization of the M2 muscarinic acetylcholine receptor. The Journal of Biological Chemistry. 275: 23295-302. PMID 10930431 DOI: 10.1074/Jbc.M002380200  0.815
2000 Gibson RM, Schiemann WP, Prichard LB, Reno JM, Ericsson LH, Nathanson NM. Phosphorylation of human gp130 at Ser-782 adjacent to the Di-leucine internalization motif. Effects on expression and signaling. The Journal of Biological Chemistry. 275: 22574-82. PMID 10811661 DOI: 10.1074/jbc.M907658199  0.37
2000 Bartoe JL, Nathanson NM. Differential regulation of leukemia inhibitory factor-stimulated neuronal gene expression by protein phosphatases SHP-1 and SHP-2 through mitogen-activated protein kinase-dependent and -independent pathways. Journal of Neurochemistry. 74: 2021-32. PMID 10800945 DOI: 10.1046/J.1471-4159.2000.0742021.X  0.796
2000 Rouse ST, Hamilton SE, Potter LT, Nathanson NM, Conn PJ. Muscarinic-induced modulation of potassium conductances is unchanged in mouse hippocampal pyramidal cells that lack functional M1 receptors. Neuroscience Letters. 278: 61-4. PMID 10643801 DOI: 10.1016/S0304-3940(99)00914-3  0.367
1999 Shapiro MS, Loose MD, Hamilton SE, Nathanson NM, Gomeza J, Wess J, Hille B. Assignment of muscarinic receptor subtypes mediating G-protein modulation of Ca(2+) channels by using knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 96: 10899-904. PMID 10485923 DOI: 10.1073/pnas.96.19.10899  0.332
1999 Nadler LS, Rosoff ML, Hamilton SE, Kalaydjian AE, McKinnon LA, Nathanson NM. Molecular analysis of the regulation of muscarinic receptor expression and function. Life Sciences. 64: 375-9. PMID 10069499 DOI: 10.1016/S0024-3205(98)00577-3  0.427
1998 Hamilton SE, Schlador ML, McKinnon LA, Chmelar RS, Nathanson NM. Molecular mechanisms for the regulation of the expression and function of muscarinic acetylcholine receptors. Journal of Physiology, Paris. 92: 275-8. PMID 9789822 DOI: 10.1016/S0928-4257(98)80032-6  0.813
1998 Grubbs RD, Schlador ML, Nathanson NM. Site-directed mutagenesis of mAChRs demonstrates VTIL motif participation in agonist-induced sequestration and G protein coupling Faseb Journal. 12: A742. DOI: 10.1016/S0024-3205(99)90480-0  0.761
1997 Hamilton SE, Loose MD, Qi M, Levey AI, Hille B, McKnight GS, Idzerda RL, Nathanson NM. Disruption of the m1 receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 13311-6. PMID 9371842 DOI: 10.1073/Pnas.94.24.13311  0.398
1997 Thomas SL, Chmelar RS, Lu C, Halvorsen SW, Nathanson NM. Tissue-specific regulation of G-protein-coupled inwardly rectifying K+ channel expression by muscarinic receptor activation in ovo. The Journal of Biological Chemistry. 272: 29958-62. PMID 9368074 DOI: 10.1074/jbc.272.47.29958  0.576
1997 Schlador ML, Nathanson NM. Synergistic regulation of m2 muscarinic acetylcholine receptor desensitization and sequestration by G protein-coupled receptor kinase-2 and beta-arrestin-1. The Journal of Biological Chemistry. 272: 18882-90. PMID 9228066 DOI: 10.1074/Jbc.272.30.18882  0.816
1997 Schiemann WP, Bartoe JL, Nathanson NM. Box 3-independent signaling mechanisms are involved in leukemia inhibitory factor receptor alpha- and gp130-mediated stimulation of mitogen-activated protein kinase. Evidence for participation of multiple signaling pathways which converge at Ras. The Journal of Biological Chemistry. 272: 16631-6. PMID 9195977 DOI: 10.1074/Jbc.272.26.16631  0.797
1997 McKinnon LA, Rosoff M, Hamilton SE, Schlador ML, Thomas SL, Nathanson NM. Regulation of muscarinic receptor expression and function in cultured cells and in knock-out mice. Life Sciences. 60: 1101-4. PMID 9121353 DOI: 10.1016/S0024-3205(97)00053-2  0.819
1996 Goldman PS, Schlador ML, Shapiro RA, Nathanson NM. Identification of a region required for subtype-specific agonist-induced sequestration of the m2 muscarinic acetylcholine receptor. The Journal of Biological Chemistry. 271: 4215-22. PMID 8626765 DOI: 10.1074/Jbc.271.8.4215  0.811
1995 Hamilton SE, McKinnon LA, Jackson DA, Goldman PS, Migeon JC, Habecker BA, Thomas SL, Nathanson NM. Molecular analysis of the regulation of muscarinic receptor expression and function. Life Sciences. 56: 939-43. PMID 10188796 DOI: 10.1016/0024-3205(95)00031-Z  0.42
1995 Schiemann WP, Graves LM, Baumann H, Morella KK, Gearing DP, Nielsen MD, Krebs EG, Nathanson NM. Phosphorylation of the human leukemia inhibitory factor (LIF) receptor by mitogen-activated protein kinase and the regulation of LIF receptor function by heterologous receptor activation. Proceedings of the National Academy of Sciences of the United States of America. 92: 5361-5. PMID 7777512 DOI: 10.1073/Pnas.92.12.5361  0.365
1994 Dittman AH, Weber JP, Hinds TR, Choi EJ, Migeon JC, Nathanson NM, Storm DR. A novel mechanism for coupling of m4 muscarinic acetylcholine receptors to calmodulin-sensitive adenylyl cyclases: crossover from G protein-coupled inhibition to stimulation. Biochemistry. 33: 943-51. PMID 8305442 DOI: 10.1021/Bi00170A013  0.395
1994 Morton ME, Brumwell C, Gartside CL, Hauschka SD, Nathanson NM. Characterization of muscarinic acetylcholine receptors expressed by an atrial cell line derived from a transgenic mouse tumor. Circulation Research. 74: 752-6. PMID 8137511 DOI: 10.1161/01.Res.74.4.752  0.421
1993 Habecker BA, Martin JM, Nathanson NM. Isolation and characterization of a novel cDNA which identifies both neural-specific and ubiquitously expressed GS alpha mRNAs. Journal of Neurochemistry. 61: 712-7. PMID 8336149 DOI: 10.1111/J.1471-4159.1993.Tb02177.X  0.383
1988 Luetje CW, Tietje KM, Christian JL, Nathanson NM. Differential tissue expression and developmental regulation of guanine nucleotide binding regulatory proteins and their messenger RNAs in rat heart. The Journal of Biological Chemistry. 263: 13357-65. PMID 3138235  0.526
1988 Luetje CW, Nathanson NM. Chronic membrane depolarization regulates the level of the guanine nucleotide binding protein Go alpha in cultured neuronal cells. Journal of Neurochemistry. 50: 1775-82. PMID 3131483  0.563
1988 Subers EM, Liles WC, Luetje CW, Nathanson NM. Biochemical and immunological studies on the regulation of cardiac and neuronal muscarinic acetylcholine receptor number and function. Trends in Pharmacological Sciences. 25-8. PMID 3074532  0.601
1988 Martin JM, Liles WC, Nathanson NM. Modification of neuronal muscarinic receptor-mediated responses by islet-activating protein. Brain Research. 455: 370-6. PMID 2841015 DOI: 10.1016/0006-8993(88)90097-2  0.383
1987 Luetje CW, Brumwell C, Norman MG, Peterson GL, Schimerlik MI, Nathanson NM. Isolation and characterization of monoclonal antibodies specific for the cardiac muscarinic acetylcholine receptor. Biochemistry. 26: 6892-6. PMID 3427051 DOI: 10.1021/Bi00396A003  0.613
1987 Luetje CW, Gierschik P, Milligan G, Unson C, Spiegel A, Nathanson NM. Tissue-specific regulation of GTP-binding protein and muscarinic acetylcholine receptor levels during cardiac development. Biochemistry. 26: 4876-84. PMID 3117107 DOI: 10.1021/Bi00389A040  0.536
1987 Martin JM, Subers EM, Halvorsen SW, Nathanson NM. Functional and physical properties of chick atrial and ventricular GTP-binding proteins: relationship to muscarinic acetylcholine receptor-mediated responses. The Journal of Pharmacology and Experimental Therapeutics. 240: 683-8. PMID 3100779  0.554
1987 Selfe S, Hunter DD, Shattuck RL, Nathanson NM, Storm DR. Alteration of intracellular cAMP levels and beating rates of cultured chick cardiac cells by Bordetella pertussis adenylate cyclase. Molecular Pharmacology. 31: 529-34. PMID 2883570  0.681
1986 Hunter DD, Nathanson NM. Biochemical and physical analyses of newly synthesized muscarinic acetylcholine receptors in cultured embryonic chicken cardiac cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 3739-48. PMID 3098931  0.681
1986 Liles WC, Hunter DD, Meier KE, Nathanson NM. Activation of protein kinase C induces rapid internalization and subsequent degradation of muscarinic acetylcholine receptors in neuroblastoma cells. The Journal of Biological Chemistry. 261: 5307-13. PMID 3082882  0.739
1985 Martin JM, Hunter DD, Nathanson NM. Islet activating protein inhibits physiological responses evoked by cardiac muscarinic acetylcholine receptors. Role of guanosine triphosphate binding proteins in regulation of potassium permeability. Biochemistry. 24: 7521-5. PMID 2418867 DOI: 10.1021/Bi00347A003  0.717
1985 Hunter DD, Nathanson NM. Assay of muscarinic acetylcholine receptor function in cultured cardiac cells by stimulation of 86Rb+ efflux. Analytical Biochemistry. 149: 392-8. PMID 2416241 DOI: 10.1016/0003-2697(85)90588-3  0.681
1985 Pfaffinger PJ, Martin JM, Hunter DD, Nathanson NM, Hille B. GTP-binding proteins couple cardiac muscarinic receptors to a K channel. Nature. 317: 536-8. PMID 2413367 DOI: 10.1038/317536A0  0.748
1984 Nathanson NM, Holttum J, Hunter DD, Halvorsen SW. Partial agonist activity of oxotremorine at muscarinic acetylcholine receptors in the embryonic chick heart. The Journal of Pharmacology and Experimental Therapeutics. 229: 455-8. PMID 6716268  0.726
1984 Hunter DD, Nathanson NM. Decreased physiological sensitivity mediated by newly synthesized muscarinic acetylcholine receptors in embryonic chicken heart. Proceedings of the National Academy of Sciences of the United States of America. 81: 3582-6. PMID 6587372 DOI: 10.1073/Pnas.81.11.3582  0.681
1984 Halvorsen SW, Nathanson NM. Ontogenesis of physiological responsiveness and guanine nucleotide sensitivity of cardiac muscarinic receptors during chick embryonic development. Biochemistry. 23: 5813-21. PMID 6543143 DOI: 10.1021/Bi00319A021  0.436
1983 Halvorsen SW, Engel B, Hunter DD, Nathanson NM. Development and regulation of cardiac muscarinic acetylcholine receptor number, function and guanyl nucleotide sensitivity. Advances in Experimental Medicine and Biology. 161: 143-58. PMID 6135305 DOI: 10.1007/978-1-4684-4472-8_8  0.726
1981 Halvorsen SW, Nathanson NM. In vivo regulation of muscarinic acetylcholine receptor number and function in embryonic chick heart. The Journal of Biological Chemistry. 256: 7941-8. PMID 7263635  0.436
1980 Nathanson NM, Hall ZW. In situ labeling of Torpedo and rat muscle acetylcholine receptor by a photoaffinity derivative of alpha-bungarotoxin. The Journal of Biological Chemistry. 255: 1698-703. PMID 7354049  0.605
1979 Klein WL, Nathanson N, Nirenberg M. Muscarinic acetylcholine receptor regulation by accelerated rate of receptor loss. Biochemical and Biophysical Research Communications. 90: 506-12. PMID 508317 DOI: 10.1016/0006-291X(79)91264-6  0.72
1979 Nathanson NM, Hall ZW. Subunit structure and peptide mapping of junctional and extrajunctional acetylcholine receptors from rat muscle. Biochemistry. 18: 3392-401. PMID 465480 DOI: 10.1021/Bi00582A028  0.62
1978 Nathanson NM, Klein WL, Nirenberg M. Regulation of adenylate cyclase activity mediated by muscarinic acetylcholine receptors. Proceedings of the National Academy of Sciences of the United States of America. 75: 1788-91. PMID 205870  0.674
1975 Nathanson NM, Schleif R. Paucity of sites mutable to constitutivity in the araC activator gene of the L-arabinose operon of Escherichia coli. Journal of Molecular Biology. 96: 185-99. PMID 1099212 DOI: 10.1016/0022-2836(75)90190-4  0.524
1973 Nathanson NM, Schleif R. Novel mutation to dominant fucose resistance in the L-arabinose operon of Escherichia coli. Journal of Bacteriology. 115: 711-3. PMID 4579880 DOI: 10.1128/Jb.115.2.711-713.1973  0.524
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