Ellen Unterwald - Publications

Affiliations: 
Temple Univ Sch Med, Philadelphia, PA, United States 
Area:
neuropharmacology

108 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Brailoiu GC, Deliu E, Console Bram LM, Soboloff J, Abood ME, Unterwald EM, Brailoiu E. Cocaine Inhibits Store-Operated Ca2+ Entry in Brain Microvascular Endothelial Cells: Critical Role for Sigma-1 Receptors. The Biochemical Journal. PMID 26467159 DOI: 10.1042/BJ20150934  1
2015 Barr JL, Rasmussen BA, Tallarida CS, Scholl JL, Forster GL, Unterwald EM, Rawls SM. Ceftriaxone attenuates acute cocaine-evoked dopaminergic neurotransmission in the nucleus accumbens of the rat. British Journal of Pharmacology. PMID 26375494 DOI: 10.1111/bph.13330  1
2015 Enman NM, Arthur K, Ward SJ, Perrine SA, Unterwald EM. Anhedonia, Reduced Cocaine Reward, and Dopamine Dysfunction in a Rat Model of Posttraumatic Stress Disorder. Biological Psychiatry. PMID 26115790 DOI: 10.1016/j.biopsych.2015.04.024  1
2015 Barr JL, Deliu E, Brailoiu GC, Zhao P, Yan G, Abood ME, Unterwald EM, Brailoiu E. Mechanisms of activation of nucleus accumbens neurons by cocaine via sigma-1 receptor-inositol 1,4,5-trisphosphate-transient receptor potential canonical channel pathways. Cell Calcium. 58: 196-207. PMID 26077147 DOI: 10.1016/j.ceca.2015.05.001  1
2015 Craige CP, Lewandowski S, Kirby LG, Unterwald EM. Dorsal raphe 5-HT(2C) receptor and GABA networks regulate anxiety produced by cocaine withdrawal. Neuropharmacology. 93: 41-51. PMID 25656481 DOI: 10.1016/j.neuropharm.2015.01.021  1
2015 Barr JL, Unterwald EM. Activity-regulated gene expression in immature neurons in the dentate gyrus following re-exposure to a cocaine-paired environment. Hippocampus. 25: 354-62. PMID 25294309 DOI: 10.1002/hipo.22377  1
2015 Kravets JL, Reyes BA, Unterwald EM, Van Bockstaele EJ. Direct targeting of peptidergic amygdalar neurons by noradrenergic afferents: linking stress-integrative circuitry. Brain Structure & Function. 220: 541-58. PMID 24271021 DOI: 10.1007/s00429-013-0674-8  1
2014 Parikh V, Naughton SX, Shi X, Kelley LK, Yegla B, Tallarida CS, Rawls SM, Unterwald EM. Cocaine-induced neuroadaptations in the dorsal striatum: glutamate dynamics and behavioral sensitization. Neurochemistry International. 75: 54-65. PMID 24911954 DOI: 10.1016/j.neuint.2014.05.016  1
2014 Barr JL, Forster GL, Unterwald EM. Repeated cocaine enhances ventral hippocampal-stimulated dopamine efflux in the nucleus accumbens and alters ventral hippocampal NMDA receptor subunit expression. Journal of Neurochemistry. 130: 583-90. PMID 24832868 DOI: 10.1111/jnc.12764  1
2014 Shi X, Miller JS, Harper LJ, Poole RL, Gould TJ, Unterwald EM. Reactivation of cocaine reward memory engages the Akt/GSK3/mTOR signaling pathway and can be disrupted by GSK3 inhibition. Psychopharmacology. 231: 3109-18. PMID 24595501 DOI: 10.1007/s00213-014-3491-8  1
2014 Miller JS, Barr JL, Harper LJ, Poole RL, Gould TJ, Unterwald EM. The GSK3 signaling pathway is activated by cocaine and is critical for cocaine conditioned reward in mice. Plos One. 9: e88026. PMID 24505362 DOI: 10.1371/journal.pone.0088026  1
2014 Enman NM, Zhang Y, Unterwald EM. Connecting the pathology of posttraumatic stress and substance use disorders: monoamines and neuropeptides. Pharmacology, Biochemistry, and Behavior. 117: 61-9. PMID 24333548 DOI: 10.1016/j.pbb.2013.12.001  1
2013 Unterwald EM, Page ME, Brown TB, Miller JS, Ruiz M, Pescatore KA, Xu B, Reichardt LF, Beverley J, Tang B, Steiner H, Thomas EA, Ehrlich ME. Behavioral and transcriptome alterations in male and female mice with postnatal deletion of TrkB in dorsal striatal medium spiny neurons. Molecular Neurodegeneration. 8: 47. PMID 24369067 DOI: 10.1186/1750-1326-8-47  1
2013 Xu W, Wang Y, Ma Z, Chiu YT, Huang P, Rasakham K, Unterwald E, Lee DY, Liu-Chen LY. L-isocorypalmine reduces behavioral sensitization and rewarding effects of cocaine in mice by acting on dopamine receptors. Drug and Alcohol Dependence. 133: 693-703. PMID 24080315 DOI: 10.1016/j.drugalcdep.2013.08.021  1
2013 Xu W, Chen C, Li JG, Dimattio K, Wang Y, Unterwald E, Liu-Chen LY. PKA and ERK1/2 are involved in dopamine D₁ receptor-induced heterologous desensitization of the δ opioid receptor. Life Sciences. 92: 1101-9. PMID 23624231 DOI: 10.1016/j.lfs.2013.04.006  1
2013 Craige CP, Unterwald EM. Serotonin (2C) receptor regulation of cocaine-induced conditioned place preference and locomotor sensitization. Behavioural Brain Research. 238: 206-10. PMID 23103406 DOI: 10.1016/j.bbr.2012.10.034  1
2013 Craige CP, Enman NM, Unterwald EM. Stress, Anxiety, and Cocaine Abuse The Effects of Drug Abuse On the Human Nervous System. 135-167. DOI: 10.1016/B978-0-12-418679-8.00006-X  1
2012 Reith ME, Ali S, Hashim A, Sheikh IS, Theddu N, Gaddiraju NV, Mehrotra S, Schmitt KC, Murray TF, Sershen H, Unterwald EM, Davis FA. Novel C-1 substituted cocaine analogs unlike cocaine or benztropine. The Journal of Pharmacology and Experimental Therapeutics. 343: 413-25. PMID 22895898 DOI: 10.1124/jpet.112.193771  0.52
2012 Enman NM, Unterwald EM. Inhibition of GSK3 attenuates amphetamine-induced hyperactivity and sensitization in the mouse. Behavioural Brain Research. 231: 217-25. PMID 22649795 DOI: 10.1016/j.bbr.2012.03.027  1
2011 Rasmussen B, Unterwald EM, Rawls SM. Glutamate transporter subtype 1 (GLT-1) activator ceftriaxone attenuates amphetamine-induced hyperactivity and behavioral sensitization in rats. Drug and Alcohol Dependence. 118: 484-8. PMID 21524862 DOI: 10.1016/j.drugalcdep.2011.03.022  1
2011 Persidsky Y, Ho W, Ramirez SH, Potula R, Abood ME, Unterwald E, Tuma R. HIV-1 infection and alcohol abuse: neurocognitive impairment, mechanisms of neurodegeneration and therapeutic interventions. Brain, Behavior, and Immunity. 25: S61-70. PMID 21397004 DOI: 10.1016/j.bbi.2011.03.001  1
2011 Rasmussen BA, Baron DA, Kim JK, Unterwald EM, Rawls SM. β-Lactam antibiotic produces a sustained reduction in extracellular glutamate in the nucleus accumbens of rats. Amino Acids. 40: 761-4. PMID 20383795 DOI: 10.1007/s00726-010-0589-0  1
2011 Unterwald EM. Upregulating G protein-coupled receptors with receptor antagonists Neuromethods. 60: 403-419. DOI: 10.1007/978-1-61779-179-6_20  1
2010 Nwaneshiudu CA, Unterwald EM. NK-3 receptor antagonism prevents behavioral sensitization to cocaine: a role of glycogen synthase kinase-3 in the nucleus accumbens. Journal of Neurochemistry. 115: 635-42. PMID 20807318 DOI: 10.1111/j.1471-4159.2010.06973.x  1
2010 Randall-Thompson JF, Pescatore KA, Unterwald EM. A role for delta opioid receptors in the central nucleus of the amygdala in anxiety-like behaviors. Psychopharmacology. 212: 585-95. PMID 20730419 DOI: 10.1007/s00213-010-1980-y  1
2010 Carvalho AF, Reyes AR, Sterling RC, Unterwald E, Van Bockstaele EJ. Contribution of limbic norepinephrine to cannabinoid-induced aversion. Psychopharmacology. 211: 479-91. PMID 20602088 DOI: 10.1007/s00213-010-1923-7  1
2010 Walsh SL, Unterwald EM, Izenwasser S. Introduction to the College on Problems of Drug Dependence special issue: contemporary advances in opioid neuropharmacology. Drug and Alcohol Dependence. 108: 153-5. PMID 20378280 DOI: 10.1016/j.drugalcdep.2010.03.001  1
2010 Miller JS, Tallarida RJ, Unterwald EM. Inhibition of GSK3 attenuates dopamine D1 receptor agonist-induced hyperactivity in mice. Brain Research Bulletin. 82: 184-7. PMID 20347018 DOI: 10.1016/j.brainresbull.2010.03.005  1
2010 Trecki J, Brailoiu GC, Unterwald EM. Localization of CXCR4 in the forebrain of the adult rat. Brain Research. 1315: 53-62. PMID 20026091 DOI: 10.1016/j.brainres.2009.12.015  1
2010 Rasmussen BA, Unterwald EM, Kim JK, Rawls SM. Methanandamide blocks amphetamine-induced behavioral sensitization in rats. European Journal of Pharmacology. 627: 150-5. PMID 19879869 DOI: 10.1016/j.ejphar.2009.10.059  1
2009 Huang P, Liu-Chen LY, Unterwald EM, Cowan A. Hyperlocomotion and paw tremors are two highly quantifiable signs of SR141716-precipitated withdrawal from delta9-tetrahydrocannabinol in C57BL/6 mice. Neuroscience Letters. 465: 66-70. PMID 19733208 DOI: 10.1016/j.neulet.2009.08.073  1
2009 Soderman AR, Unterwald EM. Cocaine-induced mu opioid receptor occupancy within the striatum is mediated by dopamine D2 receptors. Brain Research. 1296: 63-71. PMID 19699185 DOI: 10.1016/j.brainres.2009.08.035  1
2009 Zakharova E, Miller J, Unterwald E, Wade D, Izenwasser S. Social and physical environment alter cocaine conditioned place preference and dopaminergic markers in adolescent male rats. Neuroscience. 163: 890-7. PMID 19580849 DOI: 10.1016/j.neuroscience.2009.06.068  1
2009 Schroeder JA, McCafferty MR, Unterwald EM. Regulation of dynamin 2 and G protein-coupled receptor kinase 2 in rat nucleus accumbens during acute and repeated cocaine administration. Synapse (New York, N.Y.). 63: 863-70. PMID 19562697 DOI: 10.1002/syn.20669  1
2009 Nwaneshiudu CA, Unterwald EM. Blockade of neurokinin-3 receptors modulates dopamine-mediated behavioral hyperactivity. Neuropharmacology. 57: 295-301. PMID 19500601 DOI: 10.1016/j.neuropharm.2009.05.008  1
2009 Rasmussen BA, Kim E, Unterwald EM, Rawls SM. Methanandamide attenuates cocaine-induced hyperthermia in rats by a cannabinoid CB1-dopamine D2 receptor mechanism. Brain Research. 1260: 7-14. PMID 19401177 DOI: 10.1016/j.brainres.2008.12.078  1
2009 Miller JS, Tallarida RJ, Unterwald EM. Cocaine-induced hyperactivity and sensitization are dependent on GSK3. Neuropharmacology. 56: 1116-23. PMID 19328817 DOI: 10.1016/j.neuropharm.2009.03.006  1
2009 Trecki J, Unterwald EM. Modulation of cocaine-induced activity by intracerebral administration of CXCL12. Neuroscience. 161: 13-22. PMID 19303923 DOI: 10.1016/j.neuroscience.2009.03.027  1
2008 Unterwald EM. Naltrexone in the treatment of alcohol dependence. Journal of Addiction Medicine. 2: 121-7. PMID 21768981 DOI: 10.1097/ADM.0b013e318182b20f  1
2008 Perrine SA, Miller JS, Unterwald EM. Cocaine regulates protein kinase B and glycogen synthase kinase-3 activity in selective regions of rat brain. Journal of Neurochemistry. 107: 570-7. PMID 18717814 DOI: 10.1111/j.1471-4159.2008.05632.x  1
2008 Soderman AR, Unterwald EM. Cocaine reward and hyperactivity in the rat: sites of mu opioid receptor modulation. Neuroscience. 154: 1506-16. PMID 18550291 DOI: 10.1016/j.neuroscience.2008.04.063  1
2008 Ambrose-Lanci LM, Peiris NB, Unterwald EM, Van Bockstaele EJ. Cocaine withdrawal-induced trafficking of delta-opioid receptors in rat nucleus accumbens. Brain Research. 1210: 92-102. PMID 18417105 DOI: 10.1016/j.brainres.2008.02.105  1
2008 Tropea TF, Guerriero RM, Willuhn I, Unterwald EM, Ehrlich ME, Steiner H, Kosofsky BE. Augmented D1 dopamine receptor signaling and immediate-early gene induction in adult striatum after prenatal cocaine. Biological Psychiatry. 63: 1066-74. PMID 18275938 DOI: 10.1016/j.biopsych.2007.12.002  1
2008 Niculescu M, Perrine SA, Miller JS, Ehrlich ME, Unterwald EM. Trk: a neuromodulator of age-specific behavioral and neurochemical responses to cocaine in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1198-207. PMID 18234897 DOI: 10.1523/JNEUROSCI.0988-07.2008  1
2008 Perrine SA, Sheikh IS, Nwaneshiudu CA, Schroeder JA, Unterwald EM. Withdrawal from chronic administration of cocaine decreases delta opioid receptor signaling and increases anxiety- and depression-like behaviors in the rat. Neuropharmacology. 54: 355-64. PMID 18045627 DOI: 10.1016/j.neuropharm.2007.10.007  1
2008 Huang P, Chen C, Xu W, Yoon SI, Unterwald EM, Pintar JE, Wang Y, Chong PL, Liu-Chen LY. Brain region-specific N-glycosylation and lipid rafts association of the rat mu opioid receptor. Biochemical and Biophysical Research Communications. 365: 82-8. PMID 17980152 DOI: 10.1016/j.bbrc.2007.10.128  1
2007 Huang P, Xu W, Yoon SI, Chen C, Chong PL, Unterwald EM, Liu-Chen LY. Agonist treatment did not affect association of mu opioid receptors with lipid rafts and cholesterol reduction had opposite effects on the receptor-mediated signaling in rat brain and CHO cells. Brain Research. 1184: 46-56. PMID 17980352 DOI: 10.1016/j.brainres.2007.09.096  1
2007 Schroeder JA, Hummel M, Simpson AD, Sheikh R, Soderman AR, Unterwald EM. A role for mu opioid receptors in cocaine-induced activity, sensitization, and reward in the rat. Psychopharmacology. 195: 265-72. PMID 17687547 DOI: 10.1007/s00213-007-0883-z  1
2006 Hummel M, Schroeder J, Liu-Chen LY, Cowan A, Unterwald EM. An antisense oligodeoxynucleotide to the mu opioid receptor attenuates cocaine-induced behavioral sensitization and reward in mice. Neuroscience. 142: 481-91. PMID 16893609 DOI: 10.1016/j.neuroscience.2006.06.013  1
2006 Wang Y, Dun SL, Huang P, Chen C, Chen Y, Unterwald EM, Dun NJ, Van Bockstaele EJ, Liu-Chen LY. Distribution and ultrastructural localization of GEC1 in the rat CNS. Neuroscience. 140: 1265-76. PMID 16650615 DOI: 10.1016/j.neuroscience.2006.03.013  1
2006 Ambrose LM, Gallagher SM, Unterwald EM, Van Bockstaele EJ. Dopamine-D1 and delta-opioid receptors co-exist in rat striatal neurons. Neuroscience Letters. 399: 191-6. PMID 16517070 DOI: 10.1016/j.neulet.2006.02.027  1
2006 Perrine SA, Hoshaw BA, Unterwald EM. Delta opioid receptor ligands modulate anxiety-like behaviors in the rat. British Journal of Pharmacology. 147: 864-72. PMID 16491101 DOI: 10.1038/sj.bjp.0706686  1
2005 Niculescu M, Ehrlich ME, Unterwald EM. Age-specific behavioral responses to psychostimulants in mice. Pharmacology, Biochemistry, and Behavior. 82: 280-8. PMID 16199081 DOI: 10.1016/j.pbb.2005.08.014  1
2005 Muller DL, Unterwald EM. D1 dopamine receptors modulate deltaFosB induction in rat striatum after intermittent morphine administration. The Journal of Pharmacology and Experimental Therapeutics. 314: 148-54. PMID 15772255 DOI: 10.1124/jpet.105.083410  1
2005 Perrine SA, Schroeder JA, Unterwald EM. Behavioral sensitization to binge-pattern cocaine administration is not associated with changes in protein levels of four major G-proteins. Brain Research. Molecular Brain Research. 133: 224-32. PMID 15710239 DOI: 10.1016/j.molbrainres.2004.10.025  1
2004 McCarthy LE, Mannelli P, Niculescu M, Gingrich K, Unterwald EM, Ehrlich ME. The distribution of cocaine in mice differs by age and strain. Neurotoxicology and Teratology. 26: 839-48. PMID 15451047 DOI: 10.1016/j.ntt.2004.07.004  1
2004 Schroeder JA, Hummel M, Unterwald EM. Disruption of G(i/o) protein signaling in the nucleus accumbens results in a D1 dopamine receptor-mediated hyperactivity. Pharmacology, Biochemistry, and Behavior. 79: 93-9. PMID 15388288 DOI: 10.1016/j.pbb.2004.06.004  1
2004 Ambrose LM, Unterwald EM, Van Bockstaele EJ. Ultrastructural evidence for co-localization of dopamine D2 and micro-opioid receptors in the rat dorsolateral striatum. The Anatomical Record. Part a, Discoveries in Molecular, Cellular, and Evolutionary Biology. 279: 583-91. PMID 15224400 DOI: 10.1002/ar.a.20054  1
2004 Schroeder JA, Hummel M, Unterwald EM. Repeated intracerebroventricular forskolin administration enhances behavioral sensitization to cocaine. Behavioural Brain Research. 153: 255-60. PMID 15219727 DOI: 10.1016/j.bbr.2003.12.005  1
2004 Muller DL, Unterwald EM. In vivo regulation of extracellular signal-regulated protein kinase (ERK) and protein kinase B (Akt) phosphorylation by acute and chronic morphine. The Journal of Pharmacology and Experimental Therapeutics. 310: 774-82. PMID 15056728 DOI: 10.1124/jpet.104.066548  1
2004 Hummel M, Ansonoff MA, Pintar JE, Unterwald EM. Genetic and pharmacological manipulation of mu opioid receptors in mice reveals a differential effect on behavioral sensitization to cocaine. Neuroscience. 125: 211-20. PMID 15051160 DOI: 10.1016/j.neuroscience.2004.01.025  1
2003 Unterwald EM, Ivkovic S, Cuntapay M, Stroppolo A, Guinea B, Ehrlich ME. Prenatal exposure to cocaine decreases adenylyl cyclase activity in embryonic mouse striatum. Brain Research. Developmental Brain Research. 147: 67-75. PMID 14741752 DOI: 10.1016/S0165-3806(03)00058-0  1
2003 Hummel M, Unterwald EM. Intra-accumbens pertussis toxin sensitizes rats to the locomotor activating effects of a single cocaine challenge. Brain Research. 965: 100-7. PMID 12591125 DOI: 10.1016/S0006-8993(02)04142-2  1
2003 Kruzich PJ, Chen AC, Unterwald EM, Kreek MJ. Subject-regulated dosing alters morphine self-administration behavior and morphine-stimulated [35S]GTPgammaS binding. Synapse (New York, N.Y.). 47: 243-9. PMID 12539196 DOI: 10.1002/syn.10173  1
2003 Schroeder JA, Niculescu M, Unterwald EM. Cocaine alters mu but not delta or kappa opioid receptor-stimulated in situ [35S]GTPgammaS binding in rat brain. Synapse (New York, N.Y.). 47: 26-32. PMID 12422370 DOI: 10.1002/syn.10148  1
2002 Ehrlich ME, Sommer J, Canas E, Unterwald EM. Periadolescent mice show enhanced DeltaFosB upregulation in response to cocaine and amphetamine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9155-9. PMID 12417638  1
2002 Hummel M, Unterwald EM. D1 dopamine receptor: a putative neurochemical and behavioral link to cocaine action. Journal of Cellular Physiology. 191: 17-27. PMID 11920678 DOI: 10.1002/jcp.10078  1
2001 Zhou Y, Unterwald EM, Ho A, LaForge KS, Yuferov VP, Kreuter J, Sirianni MJ, Allen RG, Kreek MJ. Ablation of pituitary pro-opiomelanocortin (POMC) cells produces alterations in hypothalamic POMC mRNA levels and midbrain mu opioid receptor binding in a conditional transgenic mouse model. Journal of Neuroendocrinology. 13: 808-17. PMID 11578531 DOI: 10.1046/j.1365-2826.2001.00702.x  1
2001 Kushner SA, Unterwald EM. Chronic cocaine administration decreases the functional coupling of GABA(B) receptors in the rat ventral tegmental area as measured by baclofen-stimulated 35S-GTPgammaS binding. Life Sciences. 69: 1093-102. PMID 11508652 DOI: 10.1016/S0024-3205(01)01203-6  1
2001 Unterwald EM. Regulation of opioid receptors by cocaine. Annals of the New York Academy of Sciences. 937: 74-92. PMID 11458541  1
2001 Unterwald EM, Kreek MJ, Cuntapay M. The frequency of cocaine administration impacts cocaine-induced receptor alterations. Brain Research. 900: 103-9. PMID 11325352 DOI: 10.1016/S0006-8993(01)02269-7  1
2000 Unterwald EM, Cuntapay M. Dopamine-opioid interactions in the rat striatum: a modulatory role for dopamine D1 receptors in delta opioid receptor-mediated signal transduction. Neuropharmacology. 39: 372-81. PMID 10698003 DOI: 10.1016/S0028-3908(99)00154-9  1
1999 Zhu Y, King MA, Schuller AG, Nitsche JF, Reidl M, Elde RP, Unterwald E, Pasternak GW, Pintar JE. Retention of supraspinal delta-like analgesia and loss of morphine tolerance in delta opioid receptor knockout mice. Neuron. 24: 243-52. PMID 10677041 DOI: 10.1016/S0896-6273(00)80836-3  1
1999 Schuller AG, King MA, Zhang J, Bolan E, Pan YX, Morgan DJ, Chang A, Czick ME, Unterwald EM, Pasternak GW, Pintar JE. Retention of heroin and morphine-6 beta-glucuronide analgesia in a new line of mice lacking exon 1 of MOR-1. Nature Neuroscience. 2: 151-6. PMID 10195199 DOI: 10.1038/5706  1
1998 Perret G, Schluger JH, Unterwald EM, Kreuter J, Ho A, Kreek MJ. Downregulation of 5-HT1A receptors in rat hypothalamus and dentate gyrus after "binge" pattern cocaine administration. Synapse (New York, N.Y.). 30: 166-71. PMID 9723786 DOI: 10.1002/(SICI)1098-2396(199810)30:2<166::AID-SYN6>3.0.CO;2-A  1
1998 Unterwald EM, Anton B, To T, Lam H, Evans CJ. Quantitative immunolocalization of mu opioid receptors: regulation by naltrexone. Neuroscience. 85: 897-905. PMID 9639282 DOI: 10.1016/S0306-4522(97)00659-3  1
1998 Maggos CE, Tsukada H, Kakiuchi T, Nishiyama S, Myers JE, Kreuter J, Schlussman SD, Unterwald EM, Ho A, Kreek MJ. Sustained withdrawal allows normalization of in vivo [11C]N-methylspiperone dopamine D2 receptor binding after chronic binge cocaine: a positron emission tomography study in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 19: 146-53. PMID 9629568 DOI: 10.1016/S0893-133X(98)00009-8  1
1997 Unterwald EM, Tsukada H, Kakiuchi T, Kosugi T, Nishiyama S, Kreek MJ. Use of positron emission tomography to measure the effects of nalmefene on D1 and D2 dopamine receptors in rat brain. Brain Research. 775: 183-8. PMID 9439841 DOI: 10.1016/S0006-8993(97)00931-1  1
1996 Unterwald EM, Fillmore J, Kreek MJ. Chronic repeated cocaine administration increases dopamine D1 receptor-mediated signal transduction. European Journal of Pharmacology. 318: 31-5. PMID 9007509 DOI: 10.1016/S0014-2999(96)00841-2  1
1996 Tsukada H, Kreuter J, Maggos CE, Unterwald EM, Kakiuchi T, Nishiyama S, Futatsubashi M, Kreek MJ. Effects of binge pattern cocaine administration on dopamine D1 and D2 receptors in the rat brain: an in vivo study using positron emission tomography. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 7670-7. PMID 8922423  1
1996 Claye LH, Unterwald EM, Ho A, Kreek MJ. Both dynorphin A(1-17) and [Des-Tyr1]dynorphin A(2-17) inhibit adenylyl cyclase activity in rat caudate putamen. The Journal of Pharmacology and Experimental Therapeutics. 277: 359-65. PMID 8613942  1
1996 Donovan DM, Miner LL, Sharpe L, Cho HJ, Takemura M, Unterwald E, Nyberg F, Kreek MJ, Uhl GR. Transgenic mice: preproenkephalin and the mu opiate receptor. Annals of the New York Academy of Sciences. 780: 19-28. PMID 8602733 DOI: 10.1111/j.1749-6632.1996.tb15108.x  1
1995 Unterwald EM, Rubenfeld JM, Imai Y, Wang JB, Uhl GR, Kreek MJ. Chronic opioid antagonist administration upregulates mu opioid receptor binding without altering mu opioid receptor mRNA levels. Brain Research. Molecular Brain Research. 33: 351-5. PMID 8750897 DOI: 10.1016/0169-328X(95)00143-G  1
1995 LaForge KS, Unterwald EM, Kreek MJ. Structure and expression of the guinea pig preproenkephalin gene: site-specific cleavage in the 3' untranslated region yields truncated mRNA transcripts in specific brain regions. Molecular and Cellular Biology. 15: 2080-9. PMID 7891703  1
1994 Unterwald EM, Ho A, Rubenfeld JM, Kreek MJ. Time course of the development of behavioral sensitization and dopamine receptor up-regulation during binge cocaine administration. The Journal of Pharmacology and Experimental Therapeutics. 270: 1387-96. PMID 7932193  1
1994 Unterwald EM, Rubenfeld JM, Kreek MJ. Repeated cocaine administration upregulates kappa and mu, but not delta, opioid receptors. Neuroreport. 5: 1613-6. PMID 7819531  1
1994 Unterwald EM, Rubenfeld JM, Spangler R, Imai Y, Wang JB, Uhl GR, Kreek MJ. Mu opioid receptor mRNA levels following chronic naltrexone administration Regulatory Peptides. 54: 307-308. DOI: 10.1016/0167-0115(94)90512-6  1
1994 Spangler R, Zhou Y, Unterwald E, Yuferov V, Ho A, Kreek MJ. Kappa opioid receptor mRNA levels in the rat brain: Effects of dopamine antagonists and cocaine Regulatory Peptides. 54: 283-284. DOI: 10.1016/0167-0115(94)90500-2  1
1994 Unterwald E, Kreek MJ. Kappa and delta opioid receptor densities following chronic repeated cocaine administration Regulatory Peptides. 53: S225-S226. DOI: 10.1016/0167-0115(94)90322-0  1
1994 Adams JU, Izenwasser S, Kramer TH, Stevens CW, Tiseo PJ, Unterwald EM. Tolerance and sensitization to opioids and cocaine Nida Research Monograph Series. 69-73.  1
1993 Unterwald EM, Cox BM, Kreek MJ, Cote TE, Izenwasser S. Chronic repeated cocaine administration alters basal and opioid-regulated adenylyl cyclase activity. Synapse (New York, N.Y.). 15: 33-8. PMID 8310423 DOI: 10.1002/syn.890150104  1
1993 Spangler R, Unterwald EM, Kreek MJ. 'Binge' cocaine administration induces a sustained increase of prodynorphin mRNA in rat caudate-putamen. Brain Research. Molecular Brain Research. 19: 323-7. PMID 7694032 DOI: 10.1016/0169-328X(93)90133-A  1
1993 Izenwasser S, Unterwald EM, Cote TE, Cox BM, Kreek MJ. Repeated, daily cocaine administration produces changes in basal and opioid-regulated adenylyl cyclase activity in rat caudate-putamen and nucleus accubens Nida Research Monograph Series. 392.  1
1993 Spangler R, Unterwald EM, Branch AD, Ho A, Kreek MJ. Chronic cocaine administration increases mRNA levels for dynorphin in the caudate putamen of rats Nida Research Monograph Series. 142.  1
1992 Unterwald EM, Horne-King J, Kreek MJ. Chronic cocaine alters brain mu opioid receptors. Brain Research. 584: 314-8. PMID 1325249 DOI: 10.1016/0006-8993(92)90912-S  1
1992 Branch AD, Unterwald EM, Lee SE, Kreek MJ. Quantitation of preproenkephalin mRNA levels in brain regions from male Fischer rats following chronic cocaine treatment using a recently developed solution hybridization assay. Brain Research. Molecular Brain Research. 14: 231-8. PMID 1279343 DOI: 10.1016/0169-328X(92)90178-E  1
1991 Unterwald EM, Knapp C, Zukin RS. Neuroanatomical localization of kappa 1 and kappa 2 opioid receptors in rat and guinea pig brain. Brain Research. 562: 57-65. PMID 1666016 DOI: 10.1016/0006-8993(91)91186-5  1
1990 Unterwald EM, Nyberg F, Terenius L, Kreek MJ. Distribution of opioid peptides in brain and GI tract: age- and species-specific differences. Nida Research Monograph. 105: 408-9. PMID 1876054  1
1990 Unterwald EM, Kreek MJ. Alterations in the expression of brain opioid receptors during senescence New Leads in Opioid Research: Proceedings of the International Narcotics Research Conference. Ics914. 200.  1
1989 Unterwald EM, Tempel A, Koob GF, Zukin RS. Characterization of opioid receptors in rat nucleus accumbens following mesolimbic dopaminergic lesions. Brain Research. 505: 111-8. PMID 2558779 DOI: 10.1016/0006-8993(89)90120-0  1
1988 Kornetsky C, Bain GT, Unterwald EM, Lewis MJ. Brain stimulation reward: effects of ethanol. Alcoholism, Clinical and Experimental Research. 12: 609-16. PMID 2852475  1
1988 Zukin RS, Eghbali M, Olive D, Unterwald EM, Tempel A. Characterization and visualization of rat and guinea pig brain kappa opioid receptors: evidence for kappa 1 and kappa 2 opioid receptors. Proceedings of the National Academy of Sciences of the United States of America. 85: 4061-5. PMID 2836869  1
1987 Unterwald E, Sasson S, Kornetsky C. Evaluation of the supraspinal analgesic activity and abuse liability of ethylketocyclazocine. European Journal of Pharmacology. 133: 275-81. PMID 3030776 DOI: 10.1016/0014-2999(87)90023-9  1
1986 Unterwald EM, Kornetsky C. Effects of nalbuphine alone and in combination with tripelennamine on rewarding brain stimulation thresholds in the rat. Pharmacology, Biochemistry, and Behavior. 25: 629-32. PMID 3774829 DOI: 10.1016/0091-3057(86)90152-8  1
1986 Sasson S, Unterwald EM, Kornetsky C. Potentiation of morphine analgesia by d-amphetamine. Psychopharmacology. 90: 163-5. PMID 3097695 DOI: 10.1007/BF00181233  1
1984 Unterwald EM, Kucharski LT, Williams JE, Kornetsky C. Tripelennamine: enhancement of brain-stimulation reward. Life Sciences. 34: 149-53. PMID 6607395 DOI: 10.1016/0024-3205(84)90585-X  1
1984 Unterwald EM, Kornetsky C. Effects of concomitant pentazocine and tripelennamine on brain-stimulation reward. Pharmacology, Biochemistry, and Behavior. 21: 961-4. PMID 6335254  1
1981 Kucharski LT, Unterwald EM. Symptomatic treatment of tardive dyskinesia: a word of caution. Schizophrenia Bulletin. 7: 571-3. PMID 6798690  1
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