Year |
Citation |
Score |
2024 |
Braunscheidel KM, Voren G, Fowler CD, Lu Q, Kuryatov A, Cameron MD, Ibañez-Tallon I, Lindstrom JM, Kamenecka TM, Kenny PJ. SR9883 is a novel small-molecule enhancer of α4β2* nicotinic acetylcholine receptor signaling that decreases intravenous nicotine self-administration in rats. Frontiers in Molecular Neuroscience. 17: 1459098. PMID 39346680 DOI: 10.3389/fnmol.2024.1459098 |
0.777 |
|
2024 |
Smith ACW, Ghoshal S, Centanni SW, Heyer MP, Corona A, Wills L, Andraka E, Lei Y, O'Connor RM, Caligiuri SPB, Khan S, Beaumont K, Sebra RP, Kieffer BL, Winder DG, ... ... Kenny PJ, et al. A master regulator of opioid reward in the ventral prefrontal cortex. Science (New York, N.Y.). 384: eadn0886. PMID 38843332 DOI: 10.1126/science.adn0886 |
0.622 |
|
2024 |
Stanley S, Devarakonda K, O'Connor R, Jimenez-Gonzalez M, Alvarsson A, Hampton R, Espinoza D, Li R, Shtekler A, Conner K, Bayne M, Garibay D, Martin J, Lehmann V, Wang L, ... Kenny P, et al. Amygdala-liver signaling orchestrates rapid glycemic responses to stress and drives stress-induced metabolic dysfunction. Research Square. PMID 38585822 DOI: 10.21203/rs.3.rs-2924278/v1 |
0.761 |
|
2024 |
Catto A, O'Connor R, Braunscheidel KM, Kenny PJ, Shen L. FABEL: Forecasting Animal Behavioral Events with Deep Learning-Based Computer Vision. Biorxiv : the Preprint Server For Biology. PMID 38559273 DOI: 10.1101/2024.03.15.584610 |
0.756 |
|
2024 |
Xu X, Zheng S, Ren J, Li Z, Li J, Xu Z, Yuan F, Yang Q, Margetts AV, Pollock TA, Vilca SJ, Yang C, Chen G, Shen P, Li S, ... ... Kenny PJ, et al. Hypothalamic CRF neurons facilitate brain reward function. Current Biology : Cb. PMID 38215742 DOI: 10.1016/j.cub.2023.12.046 |
0.768 |
|
2023 |
Chen Z, Liu XA, Kenny PJ. Central and peripheral actions of nicotine that influence blood glucose homeostasis and the development of diabetes. Pharmacological Research. 106860. PMID 37482325 DOI: 10.1016/j.phrs.2023.106860 |
0.501 |
|
2023 |
Becetti I, Bwenyi EL, de Araujo IE, Ard J, Cryan JF, Farooqi IS, Ferrario CR, Gluck ME, Holsen LM, Kenny PJ, Lawson EA, Lowell BB, Schur EA, Stanley TL, Tavakkoli A, et al. The Neurobiology of Eating Behavior in Obesity: Mechanisms and Therapeutic Targets: a Report from the 23rd Annual Harvard Nutrition Obesity Symposium. The American Journal of Clinical Nutrition. PMID 37149092 DOI: 10.1016/j.ajcnut.2023.05.003 |
0.327 |
|
2022 |
Caligiuri SPB, Howe WM, Wills L, Smith ACW, Lei Y, Bali P, Heyer MP, Moen JK, Ables JL, Elayouby KS, Williams M, Fillinger C, Oketokoun Z, Lehmann VE, DiFeliceantonio AG, ... ... Kenny PJ, et al. Hedgehog-interacting protein acts in the habenula to regulate nicotine intake. Proceedings of the National Academy of Sciences of the United States of America. 119: e2209870119. PMID 36346845 DOI: 10.1073/pnas.2209870119 |
0.79 |
|
2022 |
Wills L, Ables JL, Braunscheidel KM, Caligiuri SPB, Elayouby KS, Fillinger C, Ishikawa M, Moen JK, Kenny PJ. Neurobiological Mechanisms of Nicotine Reward and Aversion. Pharmacological Reviews. 74: 271-310. PMID 35017179 DOI: 10.1124/pharmrev.121.000299 |
0.825 |
|
2021 |
Grossman YS, Fillinger C, Manganaro A, Voren G, Waldman R, Zou T, Janssen WG, Kenny PJ, Dumitriu D. Structure and function differences in the prelimbic cortex to basolateral amygdala circuit mediate trait vulnerability in a novel model of acute social defeat stress in male mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34799681 DOI: 10.1038/s41386-021-01229-6 |
0.768 |
|
2021 |
Mathis VP, Williams M, Fillinger C, Kenny PJ. Networks of habenula-projecting cortical neurons regulate cocaine seeking. Science Advances. 7: eabj2225. PMID 34739312 DOI: 10.1126/sciadv.abj2225 |
0.772 |
|
2021 |
Bali P, Kenny PJ. Gene splicing SETs the scene for cocaine addiction. Neuron. 109: 2802-2804. PMID 34534452 DOI: 10.1016/j.neuron.2021.08.033 |
0.612 |
|
2021 |
Smith ACW, Jonkman S, Difeliceantonio AG, O'Connor RM, Ghoshal S, Romano MF, Everitt BJ, Kenny PJ. Opposing roles for striatonigral and striatopallidal neurons in dorsolateral striatum in consolidating new instrumental actions. Nature Communications. 12: 5121. PMID 34433818 DOI: 10.1038/s41467-021-25460-3 |
0.665 |
|
2021 |
Wills L, Kenny PJ. Addiction-related neuroadaptations following chronic nicotine exposure. Journal of Neurochemistry. PMID 33742685 DOI: 10.1111/jnc.15356 |
0.407 |
|
2020 |
Elayouby KS, Ishikawa M, Dukes AJ, Smith ACW, Lu Q, Fowler CD, Kenny PJ. α3* Nicotinic acetylcholine receptors in the habenula-interpeduncular nucleus circuit regulate nicotine intake. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33380469 DOI: 10.1523/JNEUROSCI.0127-19.2020 |
0.77 |
|
2020 |
Lehmann VE, Kenny PJ. Hippocampal plasticity may drive cocaine relapse. Proceedings of the National Academy of Sciences of the United States of America. 117: 30003-30005. PMID 33199642 DOI: 10.1073/pnas.2020202117 |
0.769 |
|
2020 |
Caligiuri SPB, Kenny PJ. Habenular TCF7L2 links nicotine addiction to diabetes: the broad significance. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32908242 DOI: 10.1038/s41386-020-00859-6 |
0.368 |
|
2020 |
Swinford-Jackson SE, O'Brien CP, Kenny PJ, Vanderschuren LJMJ, Unterwald EM, Pierce RC. The Persistent Challenge of Developing Addiction Pharmacotherapies. Cold Spring Harbor Perspectives in Medicine. PMID 32601131 DOI: 10.1101/cshperspect.a040311 |
0.362 |
|
2020 |
Picciotto MR, Kenny PJ. Mechanisms of Nicotine Addiction. Cold Spring Harbor Perspectives in Medicine. PMID 32341069 DOI: 10.1101/cshperspect.a039610 |
0.433 |
|
2020 |
Lepack AE, Werner CT, Stewart AF, Fulton SL, Zhong P, Farrelly LA, Smith ACW, Ramakrishnan A, Lyu Y, Bastle RM, Martin JA, Mitra S, O'Connor RM, Wang ZJ, Molina H, ... ... Kenny PJ, et al. Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking. Science (New York, N.Y.). 368: 197-201. PMID 32273471 DOI: 10.1126/Science.Aaw8806 |
0.393 |
|
2020 |
Antolin-Fontes B, Li K, Ables JL, Riad MH, Görlich A, Williams M, Wang C, Lipford SM, Dao M, Liu J, Molina H, Heintz N, Kenny PJ, Ibañez-Tallon I. The habenular G-protein-coupled receptor 151 regulates synaptic plasticity and nicotine intake. Proceedings of the National Academy of Sciences of the United States of America. PMID 32098843 DOI: 10.1073/Pnas.1916132117 |
0.811 |
|
2019 |
Bali P, Kenny PJ. Transcriptional mechanisms of drug addiction
. Dialogues in Clinical Neuroscience. 21: 379-387. PMID 31949405 DOI: 10.31887/DCNS.2019.21.4/pkenny |
0.644 |
|
2019 |
Duncan A, Heyer MP, Ishikawa M, Caligiuri SPB, Liu XA, Chen Z, Vittoria Micioni Di Bonaventura M, Elayouby KS, Ables JL, Howe WM, Bali P, Fillinger C, Williams M, O'Connor RM, Wang Z, ... ... Kenny PJ, et al. Habenular TCF7L2 links nicotine addiction to diabetes. Nature. 574: 372-377. PMID 31619789 DOI: 10.1038/S41586-019-1653-X |
0.797 |
|
2019 |
Calipari ES, Godino A, Salery M, Damez-Werno DM, Cahill ME, Werner CT, Gancarz AM, Peck EG, Jlayer Z, Rabkin J, Landry JA, Smith ACW, Defilippi P, Kenny PJ, Hurd YL, et al. Synaptic microtubule-associated protein EB3 and SRC phosphorylation mediate structural and behavioral adaptations during withdrawal from cocaine self-administration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31092585 DOI: 10.1523/Jneurosci.0024-19.2019 |
0.391 |
|
2019 |
Liu XA, Kenny PJ. Cocaine-metabolizing skin grafts. Nature Biomedical Engineering. 3: 81-82. PMID 30944434 DOI: 10.1038/s41551-019-0355-x |
0.314 |
|
2019 |
Ables J, Chen Z, Liu X, Oketokoun Z, Kenny P. F67. Exploring the Role of the Habenular-Interpeduncular Circuit in Affective States in Diabetes Biological Psychiatry. 85: S238-S239. DOI: 10.1016/J.Biopsych.2019.03.604 |
0.727 |
|
2018 |
Howe WM, Kenny PJ. Drug Addiction: Mechanisms of Nicotine Dependence Unmasked by Gene Editing. Current Biology : Cb. 28: R1205-R1207. PMID 30352192 DOI: 10.1016/j.cub.2018.09.003 |
0.386 |
|
2018 |
Chen Z, Kenny PJ. Endocannabinoid Signaling in the Habenula Regulates Adaptive Responses to Stress. Biological Psychiatry. 84: 553-554. PMID 30261976 DOI: 10.1016/J.Biopsych.2018.08.001 |
0.462 |
|
2018 |
Mathis V, Kenny PJ. Neuroscience: Brain Mechanisms of Blushing. Current Biology : Cb. 28: R791-R792. PMID 30040940 DOI: 10.1016/j.cub.2018.06.047 |
0.776 |
|
2018 |
Mathis V, Kenny PJ. From controlled to compulsive drug-taking: The role of the habenula in addiction. Neuroscience and Biobehavioral Reviews. PMID 29936111 DOI: 10.1016/j.neubiorev.2018.06.018 |
0.784 |
|
2018 |
DiFeliceantonio AG, Kenny PJ. Melanocortin 4 receptors switch reward to aversion. The Journal of Clinical Investigation. PMID 29911995 DOI: 10.1172/Jci121653 |
0.38 |
|
2018 |
Kenny PJ, Hoyer D, Koob GF. Animal Models of Addiction and Neuropsychiatric Disorders and Their Role in Drug Discovery: Honoring the Legacy of Athina Markou. Biological Psychiatry. PMID 29602521 DOI: 10.1016/J.Biopsych.2018.02.009 |
0.488 |
|
2018 |
Smith ACW, Kenny PJ. HDAC5 Regulates the Formation of Drug Memories. Trends in Molecular Medicine. PMID 29396145 DOI: 10.1016/j.molmed.2017.12.011 |
0.317 |
|
2018 |
Kenny P, Kamenecka T, Voren G, Duncan A, Howe M, Hollander J, Damez-Warno D, Lu Q, Bali P, Burli R, Gurrell I, Mather RJ, Brandon NJ. 11. Orexin-1 Receptor Antagonists as Novel Smoking Cessation Agents Biological Psychiatry. 83: S4-S5. DOI: 10.1016/J.Biopsych.2018.02.028 |
0.768 |
|
2017 |
Ables JL, Görlich A, Antolin-Fontes B, Wang C, Lipford SM, Riad MH, Ren J, Hu F, Luo M, Kenny PJ, Heintz N, Ibañez-Tallon I. Retrograde inhibition by a specific subset of interpeduncular α5 nicotinic neurons regulates nicotine preference. Proceedings of the National Academy of Sciences of the United States of America. PMID 29158387 DOI: 10.1073/Pnas.1717506114 |
0.81 |
|
2017 |
Bobadilla AC, Heinsbroek JA, Gipson CD, Griffin WC, Fowler CD, Kenny PJ, Kalivas PW. Corticostriatal plasticity, neuronal ensembles, and regulation of drug-seeking behavior. Progress in Brain Research. 235: 93-112. PMID 29054293 DOI: 10.1016/Bs.Pbr.2017.07.013 |
0.723 |
|
2017 |
Wall TR, Henderson BJ, Voren G, Wageman CR, Deshpande P, Cohen BN, Grady SR, Marks MJ, Yohannes D, Kenny PJ, Bencherif M, Lester HA. TC299423, a Novel Agonist for Nicotinic Acetylcholine Receptors. Frontiers in Pharmacology. 8: 641. PMID 29033834 DOI: 10.3389/Fphar.2017.00641 |
0.811 |
|
2017 |
Smith ACW, Kenny PJ. MicroRNAs regulate synaptic plasticity underlying drug addiction. Genes, Brain, and Behavior. PMID 28873276 DOI: 10.1111/gbb.12424 |
0.339 |
|
2017 |
Tuesta LM, Chen Z, Duncan A, Fowler CD, Ishikawa M, Lee BR, Liu XA, Lu Q, Cameron M, Hayes MR, Kamenecka TM, Pletcher M, Kenny PJ. GLP-1 acts on habenular avoidance circuits to control nicotine intake. Nature Neuroscience. PMID 28368384 DOI: 10.1038/Nn.4540 |
0.821 |
|
2017 |
Liu XA, Kenny PJ. α5 nicotinic receptors link smoking to schizophrenia. Nature Medicine. 23: 277-278. PMID 28267713 DOI: 10.1038/nm.4300 |
0.4 |
|
2016 |
Lassi G, Taylor AE, Timpson NJ, Kenny PJ, Mather RJ, Eisen T, Munafò MR. The CHRNA5-A3-B4 Gene Cluster and Smoking: From Discovery to Therapeutics. Trends in Neurosciences. PMID 27871728 DOI: 10.1016/J.Tins.2016.10.005 |
0.382 |
|
2016 |
O'Connor RM, Gururajan A, Dinan TG, Kenny PJ, Cryan JF. All Roads Lead to the miRNome: miRNAs Have a Central Role in the Molecular Pathophysiology of Psychiatric Disorders. Trends in Pharmacological Sciences. PMID 27832923 DOI: 10.1016/J.Tips.2016.10.004 |
0.406 |
|
2016 |
Cryan JF, Kenny PJ. Obituary: Athina Markou PhD (1961-2015). Neuropharmacology. PMID 27793770 DOI: 10.1016/j.neuropharm.2016.10.023 |
0.363 |
|
2016 |
Ishikawa M, Kenny PJ. Crash course in pallidus-habenula signaling. Nature Neuroscience. 19: 981-3. PMID 27459402 DOI: 10.1038/Nn.4349 |
0.346 |
|
2015 |
Chen Z, Kenny PJ. Running on Empty: Leptin Signaling in VTA Regulates Reward from Physical Activity. Cell Metabolism. 22: 540-1. PMID 26445509 DOI: 10.1016/J.Cmet.2015.09.021 |
0.532 |
|
2015 |
Wang J, Kuryatov A, Jin Z, Norleans J, Kamenecka TM, Kenny PJ, Lindstrom J. A Novel α2/α4 Subtype-Selective Positive Allosteric Modulator of Nicotinic Acetylcholine Receptors Acting From the C-tail of an α Subunit. The Journal of Biological Chemistry. PMID 26432642 DOI: 10.1074/Jbc.M115.676551 |
0.342 |
|
2015 |
Heyer MP, Kenny PJ. Corticostriatal microRNAs in addiction. Brain Research. PMID 26253823 DOI: 10.1016/j.brainres.2015.07.047 |
0.64 |
|
2015 |
Wang J, Kuryatov A, Sriram A, Jin Z, Kamenecka TM, Kenny PJ, Lindstrom J. An Accessory Agonist Binding Site Promotes Activation of α4β2* Nicotinic Acetylcholine Receptors. The Journal of Biological Chemistry. 290: 13907-18. PMID 25869137 DOI: 10.1074/Jbc.M115.646786 |
0.309 |
|
2014 |
Jonkman S, Kenny PJ. Promoting FOS to an enhanced position. Nature Neuroscience. 17: 1291-3. PMID 25254975 DOI: 10.1038/Nn.3819 |
0.615 |
|
2014 |
Heyer MP, Kenny PJ. MicroRNA-mediated repression combats depression. Neuron. 83: 253-4. PMID 25033172 DOI: 10.1016/j.neuron.2014.07.008 |
0.599 |
|
2014 |
Muschamp JW, Hollander JA, Thompson JL, Voren G, Hassinger LC, Onvani S, Kamenecka TM, Borgland SL, Kenny PJ, Carlezon WA. Hypocretin (orexin) facilitates reward by attenuating the antireward effects of its cotransmitter dynorphin in ventral tegmental area. Proceedings of the National Academy of Sciences of the United States of America. 111: E1648-55. PMID 24706819 DOI: 10.1073/Pnas.1315542111 |
0.802 |
|
2014 |
Deng JV, Wan Y, Wang X, Cohen S, Wetsel WC, Greenberg ME, Kenny PJ, Calakos N, West AE. MeCP2 phosphorylation limits psychostimulant-induced behavioral and neuronal plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4519-27. PMID 24671997 DOI: 10.1523/Jneurosci.2821-13.2014 |
0.396 |
|
2014 |
Fowler CD, Kenny PJ. Nicotine aversion: Neurobiological mechanisms and relevance to tobacco dependence vulnerability. Neuropharmacology. 76: 533-44. PMID 24055497 DOI: 10.1016/j.neuropharm.2013.09.008 |
0.742 |
|
2013 |
Fowler CD, Tuesta L, Kenny PJ. Role of α5* nicotinic acetylcholine receptors in the effects of acute and chronic nicotine treatment on brain reward function in mice. Psychopharmacology. PMID 23958943 DOI: 10.1007/S00213-013-3235-1 |
0.821 |
|
2013 |
Kenny PJ, Voren G, Johnson PM. Dopamine D2 receptors and striatopallidal transmission in addiction and obesity. Current Opinion in Neurobiology. 23: 535-8. PMID 23726225 DOI: 10.1016/J.Conb.2013.04.012 |
0.794 |
|
2013 |
Bali P, Kenny PJ. MicroRNAs and Drug Addiction. Frontiers in Genetics. 4: 43. PMID 23717324 DOI: 10.3389/fgene.2013.00043 |
0.646 |
|
2013 |
Lotfipour S, Byun JS, Leach P, Fowler CD, Murphy NP, Kenny PJ, Gould TJ, Boulter J. Targeted deletion of the mouse α2 nicotinic acetylcholine receptor subunit gene (Chrna2) potentiates nicotine-modulated behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 7728-41. PMID 23637165 DOI: 10.1523/Jneurosci.4731-12.2013 |
0.715 |
|
2013 |
Bough KJ, Lerman C, Rose JE, McClernon FJ, Kenny PJ, Tyndale RF, David SP, Stein EA, Uhl GR, Conti DV, Green C, Amur S. Biomarkers for smoking cessation. Clinical Pharmacology and Therapeutics. 93: 526-38. PMID 23588313 DOI: 10.1038/Clpt.2013.57 |
0.306 |
|
2013 |
Picciotto MR, Kenny PJ. Molecular mechanisms underlying behaviors related to nicotine addiction. Cold Spring Harbor Perspectives in Medicine. 3: a012112. PMID 23143843 DOI: 10.1101/cshperspect.a012112 |
0.464 |
|
2013 |
Jonkman S, Kenny PJ. Molecular, cellular, and structural mechanisms of cocaine addiction: a key role for microRNAs. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 198-211. PMID 22968819 DOI: 10.1038/Npp.2012.120 |
0.654 |
|
2012 |
Harmey D, Griffin PR, Kenny PJ. Development of novel pharmacotherapeutics for tobacco dependence: progress and future directions. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 14: 1300-18. PMID 23024249 DOI: 10.1093/ntr/nts201 |
0.38 |
|
2012 |
Prins J, Kenny PJ, Doomernik I, Schreiber R, Olivier B, Mechiel Korte S. The triple reuptake inhibitor DOV 216,303 induces long-lasting enhancement of brain reward activity as measured by intracranial self-stimulation in rats. European Journal of Pharmacology. 693: 51-6. PMID 23010469 DOI: 10.1016/J.Ejphar.2012.07.047 |
0.36 |
|
2012 |
Heyer MP, Pani AK, Smeyne RJ, Kenny PJ, Feng G. Normal midbrain dopaminergic neuron development and function in miR-133b mutant mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10887-94. PMID 22875923 DOI: 10.1523/Jneurosci.1732-12.2012 |
0.672 |
|
2012 |
Hollander JA, Pham D, Fowler CD, Kenny PJ. Hypocretin-1 receptors regulate the reinforcing and reward-enhancing effects of cocaine: pharmacological and behavioral genetics evidence. Frontiers in Behavioral Neuroscience. 6: 47. PMID 22837742 DOI: 10.3389/fnbeh.2012.00047 |
0.799 |
|
2012 |
Pierce RC, O'Brien CP, Kenny PJ, Vanderschuren LJ. Rational development of addiction pharmacotherapies: successes, failures, and prospects. Cold Spring Harbor Perspectives in Medicine. 2: a012880. PMID 22675669 DOI: 10.1101/cshperspect.a012880 |
0.384 |
|
2012 |
Jiang R, Song X, Bali P, Smith A, Bayona CR, Lin L, Cameron MD, McDonald PH, Kenny PJ, Kamenecka TM. Disubstituted piperidines as potent orexin (hypocretin) receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 22: 3890-4. PMID 22617492 DOI: 10.1016/J.Bmcl.2012.04.122 |
0.611 |
|
2012 |
Im HI, Kenny PJ. MicroRNAs in neuronal function and dysfunction. Trends in Neurosciences. 35: 325-34. PMID 22436491 DOI: 10.1016/j.tins.2012.01.004 |
0.572 |
|
2012 |
Miller BH, Zeier Z, Xi L, Lanz TA, Deng S, Strathmann J, Willoughby D, Kenny PJ, Elsworth JD, Lawrence MS, Roth RH, Edbauer D, Kleiman RJ, Wahlestedt C. MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function. Proceedings of the National Academy of Sciences of the United States of America. 109: 3125-30. PMID 22315408 DOI: 10.1073/Pnas.1113793109 |
0.534 |
|
2012 |
Fowler CD, Kenny PJ. Utility of genetically modified mice for understanding the neurobiology of substance use disorders. Human Genetics. 131: 941-57. PMID 22190154 DOI: 10.1007/s00439-011-1129-z |
0.663 |
|
2012 |
Zhou L, Ghee SM, Chan C, Lin L, Cameron MD, Kenny PJ, See RE. Orexin-1 receptor mediation of cocaine seeking in male and female rats. The Journal of Pharmacology and Experimental Therapeutics. 340: 801-9. PMID 22186370 DOI: 10.1124/Jpet.111.187567 |
0.334 |
|
2012 |
Fowler CD, Kenny PJ. Habenular signaling in nicotine reinforcement. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 306-7. PMID 22157872 DOI: 10.1038/npp.2011.197 |
0.724 |
|
2012 |
Hollander JA, Kenny PJ. Compulsive drug use and brain reward systems Drug Abuse and Addiction in Medical Illness: Causes, Consequences and Treatment. 2147483647: 63-72. DOI: 10.1007/978-1-4614-3375-0_5 |
0.456 |
|
2011 |
Ahmed SH, Kenny PJ. Cracking the molecular code of cocaine addiction. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 52: 309-20. PMID 23382145 DOI: 10.1093/ilar.52.3.309 |
0.39 |
|
2011 |
Kenny PJ. Common cellular and molecular mechanisms in obesity and drug addiction. Nature Reviews. Neuroscience. 12: 638-51. PMID 22011680 DOI: 10.1038/nrn3105 |
0.329 |
|
2011 |
Kenny PJ. 'Macrophage' cannabinoid receptor goes up in smoke. Nature Neuroscience. 14: 1100-2. PMID 21878924 DOI: 10.1038/nn.2912 |
0.389 |
|
2011 |
Tuesta LM, Fowler CD, Kenny PJ. Recent advances in understanding nicotinic receptor signaling mechanisms that regulate drug self-administration behavior. Biochemical Pharmacology. 82: 984-95. PMID 21740894 DOI: 10.1016/J.Bcp.2011.06.026 |
0.835 |
|
2011 |
Fowler CD, Kenny PJ. Intravenous nicotine self-administration and cue-induced reinstatement in mice: effects of nicotine dose, rate of drug infusion and prior instrumental training. Neuropharmacology. 61: 687-98. PMID 21640128 DOI: 10.1016/j.neuropharm.2011.05.012 |
0.724 |
|
2011 |
Bali P, Im HI, Kenny PJ. Methylation, memory and addiction. Epigenetics : Official Journal of the Dna Methylation Society. 6: 671-4. PMID 21586900 DOI: 10.4161/epi.6.6.15905 |
0.689 |
|
2011 |
Kenny PJ. Reward mechanisms in obesity: new insights and future directions. Neuron. 69: 664-79. PMID 21338878 DOI: 10.1016/j.neuron.2011.02.016 |
0.328 |
|
2011 |
Fowler CD, Lu Q, Johnson PM, Marks MJ, Kenny PJ. Habenular α5 nicotinic receptor subunit signalling controls nicotine intake. Nature. 471: 597-601. PMID 21278726 DOI: 10.1038/nature09797 |
0.8 |
|
2011 |
Kenny PJ. Tobacco dependence, the insular cortex and the hypocretin connection. Pharmacology, Biochemistry, and Behavior. 97: 700-7. PMID 20816891 DOI: 10.1016/j.pbb.2010.08.015 |
0.478 |
|
2010 |
Im HI, Hollander JA, Bali P, Kenny PJ. MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212. Nature Neuroscience. 13: 1120-7. PMID 20711185 DOI: 10.1038/nn.2615 |
0.775 |
|
2010 |
Contet C, Whisler KN, Jarrell H, Kenny PJ, Markou A. Patterns of responding differentiate intravenous nicotine self-administration from responding for a visual stimulus in C57BL/6J mice. Psychopharmacology. 212: 283-99. PMID 20668842 DOI: 10.1007/S00213-010-1950-4 |
0.764 |
|
2010 |
Schaefer A, Im HI, Venø MT, Fowler CD, Min A, Intrator A, Kjems J, Kenny PJ, O'Carroll D, Greengard P. Argonaute 2 in dopamine 2 receptor-expressing neurons regulates cocaine addiction. The Journal of Experimental Medicine. 207: 1843-51. PMID 20643829 DOI: 10.1084/Jem.20100451 |
0.761 |
|
2010 |
Hollander JA, Im HI, Amelio AL, Kocerha J, Bali P, Lu Q, Willoughby D, Wahlestedt C, Conkright MD, Kenny PJ. Striatal microRNA controls cocaine intake through CREB signalling. Nature. 466: 197-202. PMID 20613834 DOI: 10.1038/Nature09202 |
0.798 |
|
2010 |
Johnson PM, Kenny PJ. Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats. Nature Neuroscience. 13: 635-41. PMID 20348917 DOI: 10.1038/nn.2519 |
0.502 |
|
2010 |
Im H, Kenny PJ. Striatal microRNA controls compulsive cocaine-taking by regulating expression levels of the transcription factor MeCP2 F1000research. 1. DOI: 10.7490/F1000Research.50.1 |
0.549 |
|
2010 |
Schaefer A, Im H, Venø MT, Fowler CD, Min A, Intrator A, Kjems J, Kenny P, O'Carroll D, Greengard P. Argonaute 2 in dopamine 2 receptor–expressing neurons regulates cocaine addiction The Journal of Cell Biology. 190: i4-i4. DOI: 10.1083/JCB1902OIA4 |
0.748 |
|
2010 |
Johnson PM, Kenny PJ. Corrigendum: Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats Nature Neuroscience. 13: 1033-1033. DOI: 10.1038/Nn0810-1033C |
0.47 |
|
2009 |
Kenny PJ. Emerging therapeutic targets for the treatment of nicotine addiction. Expert Review of Clinical Pharmacology. 2: 221-5. PMID 24410700 DOI: 10.1586/ecp.09.6 |
0.412 |
|
2009 |
Kocerha J, Faghihi MA, Lopez-Toledano MA, Huang J, Ramsey AJ, Caron MG, Sales N, Willoughby D, Elmen J, Hansen HF, Orum H, Kauppinen S, Kenny PJ, Wahlestedt C. MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction. Proceedings of the National Academy of Sciences of the United States of America. 106: 3507-12. PMID 19196972 DOI: 10.1073/Pnas.0805854106 |
0.302 |
|
2009 |
Kenny PJ, Chartoff E, Roberto M, Carlezon WA, Markou A. NMDA receptors regulate nicotine-enhanced brain reward function and intravenous nicotine self-administration: role of the ventral tegmental area and central nucleus of the amygdala. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 266-81. PMID 18418357 DOI: 10.1038/Npp.2008.58 |
0.62 |
|
2008 |
Hollander JA, Lu Q, Cameron MD, Kamenecka TM, Kenny PJ. Insular hypocretin transmission regulates nicotine reward. Proceedings of the National Academy of Sciences of the United States of America. 105: 19480-5. PMID 19033203 DOI: 10.1073/pnas.0808023105 |
0.723 |
|
2008 |
Fowler CD, Arends MA, Kenny PJ. Subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: evidence from genetically modified mice. Behavioural Pharmacology. 19: 461-84. PMID 18690103 DOI: 10.1097/FBP.0b013e32830c360e |
0.734 |
|
2008 |
Johnson PM, Hollander JA, Kenny PJ. Decreased brain reward function during nicotine withdrawal in C57BL6 mice: evidence from intracranial self-stimulation (ICSS) studies. Pharmacology, Biochemistry, and Behavior. 90: 409-15. PMID 18466962 DOI: 10.1016/j.pbb.2008.03.024 |
0.671 |
|
2007 |
Kenny PJ. Brain reward systems and compulsive drug use. Trends in Pharmacological Sciences. 28: 135-41. PMID 17276521 DOI: 10.1016/j.tips.2007.01.008 |
0.342 |
|
2006 |
Kenny PJ, Chen SA, Kitamura O, Markou A, Koob GF. Conditioned withdrawal drives heroin consumption and decreases reward sensitivity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5894-900. PMID 16738231 DOI: 10.1523/JNEUROSCI.0740-06.2006 |
0.61 |
|
2006 |
Kenny PJ, Markou A. Nicotine self-administration acutely activates brain reward systems and induces a long-lasting increase in reward sensitivity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1203-11. PMID 16192981 DOI: 10.1038/sj.npp.1300905 |
0.615 |
|
2005 |
Boutrel B, Kenny PJ, Specio SE, Martin-Fardon R, Markou A, Koob GF, de Lecea L. Role for hypocretin in mediating stress-induced reinstatement of cocaine-seeking behavior. Proceedings of the National Academy of Sciences of the United States of America. 102: 19168-73. PMID 16357203 DOI: 10.1073/Pnas.0507480102 |
0.654 |
|
2005 |
Paterson NE, Bruijnzeel AW, Kenny PJ, Wright CD, Froestl W, Markou A. Prolonged nicotine exposure does not alter GABA(B) receptor-mediated regulation of brain reward function. Neuropharmacology. 49: 953-62. PMID 16005474 DOI: 10.1016/j.neuropharm.2005.04.031 |
0.575 |
|
2005 |
Kenny PJ, Markou A. Conditioned nicotine withdrawal profoundly decreases the activity of brain reward systems. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6208-12. PMID 15987950 DOI: 10.1523/JNEUROSCI.4785-04.2005 |
0.586 |
|
2005 |
Kenny PJ, Boutrel B, Gasparini F, Koob GF, Markou A. Metabotropic glutamate 5 receptor blockade may attenuate cocaine self-administration by decreasing brain reward function in rats. Psychopharmacology. 179: 247-54. PMID 15602687 DOI: 10.1007/S00213-004-2069-2 |
0.639 |
|
2005 |
Boutrel B, Kenny P, Specio S, Winsky-Sommerer R, Halfon O, Magistretti P, Markou A, Koob G, de Lecea L. A116 A KEY ROLE FOR HYPOCRETIN IN REGULATING BRAIN REWARD FUNCTION AND REINSTATEMENT FOR DRUG-SEEKING BEHAVIOR IN RATS Behavioural Pharmacology. 16: S60. DOI: 10.1097/00008877-200509001-00189 |
0.594 |
|
2005 |
Boutrel B, Kenny PJ, Markou A, Koob GF. Hypocretin and brain reward function Hypocretins: Integrators of Physiological Functions. 317-326. DOI: 10.1007/0-387-25446-3_21 |
0.53 |
|
2004 |
Kenny PJ, Markou A. The ups and downs of addiction: role of metabotropic glutamate receptors. Trends in Pharmacological Sciences. 25: 265-72. PMID 15120493 DOI: 10.1016/j.tips.2004.03.009 |
0.535 |
|
2004 |
Koob GF, Ahmed SH, Boutrel B, Chen SA, Kenny PJ, Markou A, O'Dell LE, Parsons LH, Sanna PP. Neurobiological mechanisms in the transition from drug use to drug dependence. Neuroscience and Biobehavioral Reviews. 27: 739-49. PMID 15019424 DOI: 10.1016/J.Neubiorev.2003.11.007 |
0.6 |
|
2003 |
Kenny PJ, Paterson NE, Boutrel B, Semenova S, Harrison AA, Gasparini F, Koob GF, Skoubis PD, Markou A. Metabotropic glutamate 5 receptor antagonist MPEP decreased nicotine and cocaine self-administration but not nicotine and cocaine-induced facilitation of brain reward function in rats. Annals of the New York Academy of Sciences. 1003: 415-8. PMID 14684476 DOI: 10.1196/Annals.1300.040 |
0.675 |
|
2003 |
Kenny PJ, Koob GF, Markou A. Conditioned facilitation of brain reward function after repeated cocaine administration. Behavioral Neuroscience. 117: 1103-7. PMID 14570559 DOI: 10.1037/0735-7044.117.5.1103 |
0.611 |
|
2003 |
Kenny PJ, Gasparini F, Markou A. Group II metabotropic and alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA)/kainate glutamate receptors regulate the deficit in brain reward function associated with nicotine withdrawal in rats. The Journal of Pharmacology and Experimental Therapeutics. 306: 1068-76. PMID 12805481 DOI: 10.1124/jpet.103.052027 |
0.575 |
|
2003 |
Kenny PJ, Polis I, Koob GF, Markou A. Low dose cocaine self-administration transiently increases but high dose cocaine persistently decreases brain reward function in rats. The European Journal of Neuroscience. 17: 191-5. PMID 12534985 DOI: 10.1046/j.1460-9568.2003.02443.x |
0.616 |
|
2002 |
Markou A, Kenny PJ. Neuroadaptations to chronic exposure to drugs of abuse: relevance to depressive symptomatology seen across psychiatric diagnostic categories. Neurotoxicity Research. 4: 297-313. PMID 12829420 DOI: 10.1080/10298420290023963 |
0.474 |
|
2002 |
Ahmed SH, Kenny PJ, Koob GF, Markou A. Neurobiological evidence for hedonic allostasis associated with escalating cocaine use. Nature Neuroscience. 5: 625-6. PMID 12055635 DOI: 10.1038/nn872 |
0.629 |
|
2002 |
Markou A, Kenny P. Nicotine withdrawal and antidepressants: Monoaminergic and glutamatergic modulation of reward European Neuropsychopharmacology. 12: 88-89. DOI: 10.1016/S0924-977X(02)80014-1 |
0.537 |
|
2001 |
Kenny PJ, Markou A. Neurobiology of the nicotine withdrawal syndrome. Pharmacology, Biochemistry, and Behavior. 70: 531-49. PMID 11796152 DOI: 10.1016/S0091-3057(01)00651-7 |
0.613 |
|
2001 |
Cheeta S, Irvine EE, Kenny PJ, File SE. The dorsal raphé nucleus is a crucial structure mediating nicotine's anxiolytic effects and the development of tolerance and withdrawal responses. Psychopharmacology. 155: 78-85. PMID 11374339 DOI: 10.1007/s002130100681 |
0.431 |
|
2001 |
Kenny PJ, File SE, Rattray M. Nicotine regulates 5-HT(1A) receptor gene expression in the cerebral cortex and dorsal hippocampus. The European Journal of Neuroscience. 13: 1267-71. PMID 11285026 DOI: 10.1046/j.0953-816X.2001.01501.x |
0.35 |
|
2000 |
Kenny PJ, File SE, Rattray M. Acute nicotine decreases, and chronic nicotine increases the expression of brain-derived neurotrophic factor mRNA in rat hippocampus. Brain Research. Molecular Brain Research. 85: 234-8. PMID 11146126 DOI: 10.1016/S0169-328X(00)00246-1 |
0.377 |
|
2000 |
Cheeta S, Kenny PJ, File SE. Hippocampal and septal injections of nicotine and 8-OH-DPAT distinguish among different animal tests of anxiety. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 24: 1053-67. PMID 11131172 DOI: 10.1016/S0278-5846(00)00129-9 |
0.307 |
|
2000 |
Kenny PJ, File SE, Neal MJ. Evidence for a complex influence of nicotinic acetylcholine receptors on hippocampal serotonin release. Journal of Neurochemistry. 75: 2409-14. PMID 11080192 DOI: 10.1046/j.1471-4159.2000.0752409.x |
0.35 |
|
2000 |
Cheeta S, Kenny PJ, File SE. The role of 5-HT1A receptors in mediating the anxiogenic effects of nicotine following lateral septal administration. The European Journal of Neuroscience. 12: 3797-802. PMID 11029650 DOI: 10.1046/j.1460-9568.2000.00246.x |
0.42 |
|
2000 |
File SE, Kenny PJ, Cheeta S. The role of the dorsal hippocampal serotonergic and cholinergic systems in the modulation of anxiety. Pharmacology, Biochemistry, and Behavior. 66: 65-72. PMID 10837844 DOI: 10.1016/S0091-3057(00)00198-2 |
0.354 |
|
2000 |
File SE, Cheeta S, Kenny PJ. Neurobiological mechanisms by which nicotine mediates different types of anxiety. European Journal of Pharmacology. 393: 231-6. PMID 10771018 DOI: 10.1016/S0014-2999(99)00889-4 |
0.397 |
|
2000 |
Kenny PJ, Cheeta S, File SE. Anxiogenic effects of nicotine in the dorsal hippocampus are mediated by 5-HT1A and not by muscarinic M1 receptors. Neuropharmacology. 39: 300-7. PMID 10670425 DOI: 10.1016/S0028-3908(99)00114-8 |
0.411 |
|
1999 |
Ouagazzal AM, Kenny PJ, File SE. Stimulation of nicotinic receptors in the lateral septal nucleus increases anxiety. The European Journal of Neuroscience. 11: 3957-62. PMID 10583484 DOI: 10.1046/j.1460-9568.1999.00823.x |
0.405 |
|
1999 |
Ouagazzal AM, Kenny PJ, File SE. Modulation of behaviour on trials 1 and 2 in the elevated plus-maze test of anxiety after systemic and hippocampal administration of nicotine. Psychopharmacology. 144: 54-60. PMID 10379624 DOI: 10.1007/s002130050976 |
0.377 |
|
1999 |
Kenny PJ, Cheeta S, Ouagazzal A-, Gonzalez LE, File SE. Neurochemical mechanisms by which dorsal hippocampal nicotinic acetylcholine receptors modulate anxiety European Neuropsychopharmacology. 9: 303. DOI: 10.1016/S0924-977X(99)80389-7 |
0.408 |
|
1998 |
File SE, Kenny PJ, Ouagazzal AM. Bimodal modulation by nicotine of anxiety in the social interaction test: role of the dorsal hippocampus. Behavioral Neuroscience. 112: 1423-9. PMID 9926824 DOI: 10.1037/0735-7044.112.6.1423 |
0.362 |
|
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