Year |
Citation |
Score |
2014 |
McDonald CJ, Acheff E, Kennedy R, Taylor L, Curthoys NP. Effect of lysine to alanine mutations on the phosphate activation and BPTES inhibition of glutaminase. Neurochemistry International. PMID 25510640 DOI: 10.1016/J.Neuint.2014.12.003 |
0.33 |
|
2014 |
Curthoys NP, Gstraunthaler G. pH-responsive, gluconeogenic renal epithelial LLC-PK1-FBPase+cells: a versatile in vitro model to study renal proximal tubule metabolism and function. American Journal of Physiology. Renal Physiology. 307: F1-F11. PMID 24808535 DOI: 10.1152/Ajprenal.00067.2014 |
0.467 |
|
2014 |
Curthoys NP, Moe OW. Proximal tubule function and response to acidosis. Clinical Journal of the American Society of Nephrology : Cjasn. 9: 1627-38. PMID 23908456 DOI: 10.2215/Cjn.10391012 |
0.374 |
|
2014 |
Curthoys NP. Regulation of renal glutamine metabolism during metabolic acidosis Molecular Genetics of Dysregulated Ph Homeostasis. 101-121. DOI: 10.1007/978-1-4939-1683-2_6 |
0.4 |
|
2013 |
Schauer KL, Freund DM, Prenni JE, Curthoys NP. Proteomic profiling and pathway analysis of the response of rat renal proximal convoluted tubules to metabolic acidosis. American Journal of Physiology. Renal Physiology. 305: F628-40. PMID 23804448 DOI: 10.1152/Ajprenal.00210.2013 |
0.795 |
|
2013 |
Freund DM, Prenni JE, Curthoys NP. Proteomic profiling of the mitochondrial inner membrane of rat renal proximal convoluted tubules. Proteomics. 13: 2495-9. PMID 23780708 DOI: 10.1002/Pmic.201200558 |
0.772 |
|
2013 |
Freund DM, Prenni JE, Curthoys NP. Response of the mitochondrial proteome of rat renal proximal convoluted tubules to chronic metabolic acidosis. American Journal of Physiology. Renal Physiology. 304: F145-55. PMID 23136003 DOI: 10.1152/Ajprenal.00526.2012 |
0.783 |
|
2012 |
Gummadi L, Taylor L, Curthoys NP. Concurrent binding and modifications of AUF1 and HuR mediate the pH-responsive stabilization of phosphoenolpyruvate carboxykinase mRNA in kidney cells. American Journal of Physiology. Renal Physiology. 303: F1545-54. PMID 23019227 DOI: 10.1152/Ajprenal.00400.2012 |
0.782 |
|
2012 |
Walmsley SJ, Freund DM, Curthoys NP. Proteomic profiling of the effect of metabolic acidosis on the apical membrane of the proximal convoluted tubule. American Journal of Physiology. Renal Physiology. 302: F1465-77. PMID 22357915 DOI: 10.1152/Ajprenal.00390.2011 |
0.769 |
|
2012 |
Hartwick EW, Curthoys NP. BPTES inhibition of hGA(124-551), a truncated form of human kidney-type glutaminase. Journal of Enzyme Inhibition and Medicinal Chemistry. 27: 861-7. PMID 21999665 DOI: 10.3109/14756366.2011.622272 |
0.317 |
|
2011 |
Mufti J, Hajarnis S, Shepardson K, Gummadi L, Taylor L, Curthoys NP. Role of AUF1 and HuR in the pH-responsive stabilization of phosphoenolpyruvate carboxykinase mRNA in LLC-PK₁-F⁺ cells. American Journal of Physiology. Renal Physiology. 301: F1066-77. PMID 21795643 DOI: 10.1152/Ajprenal.00303.2011 |
0.751 |
|
2011 |
Goldstrohm DA, Broeckling CD, Prenni JE, Curthoys NP. Importance of manual validation for the identification of phosphopeptides using a linear ion trap mass spectrometer. Journal of Biomolecular Techniques : Jbt. 22: 10-20. PMID 21455477 |
0.551 |
|
2010 |
Walmsley SJ, Broeckling C, Hess A, Prenni J, Curthoys NP. Proteomic analysis of brush-border membrane vesicles isolated from purified proximal convoluted tubules. American Journal of Physiology. Renal Physiology. 298: F1323-31. PMID 20219825 DOI: 10.1152/Ajprenal.00711.2009 |
0.792 |
|
2009 |
Curthoys NP. Zeta-crystallin: a tale of two cells. Kidney International. 76: 691-3. PMID 19752863 DOI: 10.1038/Ki.2009.227 |
0.434 |
|
2008 |
Ibrahim H, Lee YJ, Curthoys NP. Renal response to metabolic acidosis: Role of mRNA stabilization Kidney International. 73: 11-18. PMID 17914349 DOI: 10.1038/Sj.Ki.5002581 |
0.583 |
|
2007 |
Andratsch M, Feifel E, Taylor L, O'Hayre M, Schramek H, Curthoys NP, Gstraunthaler G. TGF-beta signaling and its effect on glutaminase expression in LLC-PK1-FBPase+ cells. American Journal of Physiology. Renal Physiology. 293: F846-53. PMID 17596530 DOI: 10.1152/Ajprenal.00139.2007 |
0.379 |
|
2007 |
Robinson MM, McBryant SJ, Tsukamoto T, Rojas C, Ferraris DV, Hamilton SK, Hansen JC, Curthoys NP. Novel mechanism of inhibition of rat kidney-type glutaminase by bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide (BPTES). The Biochemical Journal. 406: 407-14. PMID 17581113 DOI: 10.1042/Bj20070039 |
0.335 |
|
2007 |
Curthoys NP, Taylor L, Hoffert JD, Knepper MA. Proteomic analysis of the adaptive response of rat renal proximal tubules to metabolic acidosis American Journal of Physiology - Renal Physiology. 292: F140-F147. PMID 16896179 DOI: 10.1152/Ajprenal.00217.2006 |
0.545 |
|
2006 |
O'Hayre M, Taylor L, Andratsch M, Feifel E, Gstraunthaler G, Curthoys NP. Effects of constitutively active and dominant negative MAPK kinase (MKK) 3 and MKK6 on the pH-responsive increase in phosphoenolpyruvate carboxykinase mRNA. The Journal of Biological Chemistry. 281: 2982-8. PMID 16319064 DOI: 10.1074/Jbc.M510084200 |
0.479 |
|
2006 |
Schroeder JM, Ibrahim H, Taylor L, Curthoys NP. Role of deadenylation and AUF1 binding in the pH-responsive stabilization of glutaminase mRNA. American Journal of Physiology. Renal Physiology. 290: F733-40. PMID 16219914 DOI: 10.1152/Ajprenal.00250.2005 |
0.832 |
|
2006 |
Dhakras PS, Hajarnis S, Taylor L, Curthoys NP. cAMP-dependent stabilization of phosphoenolpyruvate carboxykinase mRNA in LLC-PK1-F+ kidney cells. American Journal of Physiology. Renal Physiology. 290: F313-8. PMID 16144962 DOI: 10.1152/Ajprenal.00249.2005 |
0.814 |
|
2005 |
Hajarnis S, Schroeder JM, Curthoys NP. 3'-Untranslated region of phosphoenolpyruvate carboxykinase mRNA contains multiple instability elements that bind AUF1. The Journal of Biological Chemistry. 280: 28272-80. PMID 15951444 DOI: 10.1074/Jbc.M501204200 |
0.775 |
|
2004 |
Taylor L, Curthoys NP. Glutamine metabolism: Role in acid-base balance*. Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology. 32: 291-304. PMID 21706743 DOI: 10.1002/Bmb.2004.494032050388 |
0.423 |
|
2003 |
Kenny J, Bao Y, Hamm B, Taylor L, Toth A, Wagers B, Curthoys NP. Bacterial expression, purification, and characterization of rat kidney-type mitochondrial glutaminase. Protein Expression and Purification. 31: 140-8. PMID 12963351 DOI: 10.1016/S1046-5928(03)00161-X |
0.398 |
|
2003 |
Schroeder JM, Liu W, Curthoys NP. pH-responsive stabilization of glutamate dehydrogenase mRNA in LLC-PK1-F+ cells. American Journal of Physiology. Renal Physiology. 285: F258-65. PMID 12684230 DOI: 10.1152/Ajprenal.00422.2002 |
0.83 |
|
2002 |
Feifel E, Obexer P, Andratsch M, Euler S, Taylor L, Tang A, Wei Y, Schramek H, Curthoys NP, Gstraunthaler G. p38 MAPK mediates acid-induced transcription of PEPCK in LLC-PK(1)-FBPase(+) cells. American Journal of Physiology. Renal Physiology. 283: F678-88. PMID 12217859 DOI: 10.1152/Ajprenal.00097.2002 |
0.754 |
|
2002 |
Porter LD, Ibrahim H, Taylor L, Curthoys NP. Complexity and species variation of the kidney-type glutaminase gene. Physiological Genomics. 9: 157-66. PMID 12045296 DOI: 10.1152/Physiolgenomics.00017.2002 |
0.526 |
|
2001 |
Curthoys NP, Tang A, Gstraunthaler G. pH regulation of renal gene expression Novartis Foundation Symposium. 240: 100-111. PMID 11727924 DOI: 10.1002/0470868716.Ch7 |
0.792 |
|
2001 |
Liu X, Wall QT, Taylor L, Curthoys NP. C/EBPβ contributes to cAMP-activated transcription of phosphoenolpyruvate carboxykinase in LLC-PK1-F+ cells American Journal of Physiology - Renal Physiology. 281: F649-F657. PMID 11553511 DOI: 10.1152/Ajprenal.2001.281.4.F649 |
0.393 |
|
2001 |
Curthoys NP. Role of mitochondrial glutaminase in rat renal glutamine metabolism Journal of Nutrition. 131: 2491S-2495S. PMID 11533299 DOI: 10.1093/Jn/131.9.2491S |
0.539 |
|
2001 |
Curthoys NP, Gstraunthaler G. Mechanism of increased renal gene expression during metabolic acidosis American Journal of Physiology - Renal Physiology. 281: F381-F390. PMID 11502586 DOI: 10.1152/Ajprenal.2001.281.3.F381 |
0.592 |
|
2001 |
Tang A, Curthoys NP. Identification of ζ-Crystallin/NADPH:Quinone Reductase as a Renal Glutaminase mRNA pH Response Element-binding Protein Journal of Biological Chemistry. 276: 21375-21380. PMID 11294877 DOI: 10.1074/Jbc.M101941200 |
0.78 |
|
2001 |
Taylor L, Liu X, Newsome W, Shapiro RA, Srinivasan M, Curthoys NP. Isolation and characterization of the promoter region of the rat kidney-type glutaminase gene Biochimica Et Biophysica Acta - Gene Structure and Expression. 1518: 132-136. PMID 11267668 DOI: 10.1016/S0167-4781(01)00183-X |
0.353 |
|
2000 |
Laterza OF, Taylor L, Unnithan S, Nguyen L, Curthoys NP. Mapping and functional analysis of an instability element in phosphoenolpyruvate carboxykinase mRNA American Journal of Physiology - Renal Physiology. 279: F866-F873. PMID 11053047 DOI: 10.1152/Ajprenal.2000.279.5.F866 |
0.511 |
|
2000 |
Laterza OF, Curthoys NP. Effect of acidosis on the properties of the glutaminase mRNA pH-response element binding protein Journal of the American Society of Nephrology. 11: 1583-1588. PMID 10966482 |
0.493 |
|
2000 |
Laterza OF, Curthoys NP. Specificity and functional analysis of the pH-responsive element within renal glutaminase mRNA American Journal of Physiology - Renal Physiology. 278: F970-F977. PMID 10836985 DOI: 10.1152/Ajprenal.2000.278.6.F970 |
0.564 |
|
2000 |
Holcomb T, Taylor L, Trohkimoinen J, Curthoys NP. Isolation, characterization and expression of a human brain mitochondrial glutaminase cDNA Molecular Brain Research. 76: 56-63. PMID 10719215 DOI: 10.1016/S0169-328X(99)00331-9 |
0.424 |
|
2000 |
Gstraunthaler G, Holcomb T, Feifel E, Liu W, Spitaler N, Curthoys NP. Differential expression and acid-base regulation of glutaminase mRNAs in gluconeogenic LLC-PK1-FBPase+ cells American Journal of Physiology - Renal Physiology. 278: F227-F237. PMID 10662727 DOI: 10.1152/Ajprenal.2000.278.2.F227 |
0.542 |
|
1998 |
Liu W, Feifel E, Holcomb T, Liu X, Spitaler N, Gstraunthaler G, Curthoys NP. PMA and staurosporine affect expression of the PCK gene in LLC-PK1-F+ cells American Journal of Physiology - Renal Physiology. 275: F361-F369. PMID 9729508 DOI: 10.1152/Ajprenal.1998.275.3.F361 |
0.477 |
|
1998 |
Curthoys NP. Regulation of renal glutamine metabolism: Its role in acid-base balance Faseb Journal. 12: A945. |
0.479 |
|
1997 |
Laterza OF, Hansen WR, Taylor L, Curthoys NP. Identification of an mRNA-binding protein and the specific elements that may mediate the pH-responsive induction of renal glutaminase mRNA. The Journal of Biological Chemistry. 272: 22481-8. PMID 9278399 DOI: 10.1074/Jbc.272.36.22481 |
0.477 |
|
1996 |
Liu X, Curthoys NP. CAMP activation of phosphoenol pyruvate carboxykinase transcription in renal LLC-PK1-F+ cells American Journal of Physiology. 271: F347-F355. PMID 8770166 |
0.367 |
|
1996 |
Holcomb T, Liu W, Snyder R, Shapiro R, Curthoys NP. Promoter elements that mediate the pH response of PCK mRNA in LLC-PK1-F+ cells American Journal of Physiology. 271: F340-F346. PMID 8770165 DOI: 10.1152/Ajprenal.1996.271.2.F340 |
0.518 |
|
1996 |
Hansen WR, Barsic-Tress N, Taylor L, Curthoys NP. The 3'-nontranslated region of rat renal glutaminase mRNA contains a pH-responsive stability element. The American Journal of Physiology. 271: F126-31. PMID 8760253 DOI: 10.1152/Ajprenal.1996.271.1.F126 |
0.465 |
|
1996 |
Liu X, Curthoys NP. Transcription factors which mediate cAMP activation of the phosphoenolpyruvate carboxykinase(PCK)gene in LLC-PK1-F+ cells Faseb Journal. 10: A1141. |
0.334 |
|
1995 |
Curthoys NP, Watford M. Regulation of glutaminase activity and glutamine metabolism Annual Review of Nutrition. 15: 133-159. PMID 8527215 DOI: 10.1146/Annurev.Nu.15.070195.001025 |
0.38 |
|
1995 |
Holcomb T, Curthoys NP, Gstraunthaler G. Subcellular localization of PEPCK and metabolism of gluconeogenic substrains of renal cell lines American Journal of Physiology - Cell Physiology. 268: C449-C457. PMID 7864084 DOI: 10.1152/Ajpcell.1995.268.2.C449 |
0.435 |
|
1995 |
Srinivasan M, Kalousek F, Farrell L, Curthoys NP. Role of the N-terminal 118 amino acids in the processing of the rat renal mitochondrial glutaminase precursor Journal of Biological Chemistry. 270: 1191-1197. PMID 7836379 DOI: 10.1074/Jbc.270.3.1191 |
0.303 |
|
1995 |
Srinivasan M, Kalousek F, Curthoys NP. In vitro characterization of the mitochondrial processing and the potential function of the 68-kDa subunit of renal glutaminase Journal of Biological Chemistry. 270: 1185-1190. PMID 7836378 DOI: 10.1074/Jbc.270.3.1185 |
0.352 |
|
1995 |
Porter D, Hansen WR, Taylor L, Curthoys NP. Differential expression of multiple glutaminase mRNAs in LLC-PK1-F+ cells. The American Journal of Physiology. 269: F363-73. PMID 7573485 DOI: 10.1152/Ajprenal.1995.269.3.F363 |
0.468 |
|
1993 |
Altman RA, Orr AV, Lagenaur CF, Curthoys NP, Hughey RP. Expression of rat renal gamma-glutamyltranspeptidase in LLC-PK1 cells as a model for apical targeting. Biochemistry. 32: 3822-8. PMID 8096768 DOI: 10.1021/Bi00065A039 |
0.44 |
|
1992 |
Kaiser S, Hwang JJ, Smith H, Banner C, Welbourne TC, Curthoys NP. Effect of altered acid-base balance and of various agonists on levels of renal glutamate dehydrogenase mRNA American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 262: F507-F512. PMID 1558167 DOI: 10.1152/Ajprenal.1992.262.3.F507 |
0.522 |
|
1991 |
Kaiser S, Curthoys NP. Effect of pH and bicarbonate on phosphoenolpyruvate carboxykinase and glutaminase mRNA levels in cultured renal epithelial cells Journal of Biological Chemistry. 266: 9397-9402. PMID 1851745 |
0.449 |
|
1991 |
Kaiser S, Hwang JJ, Curthoys NP. Effect of acidosis on phosphoenolpyruvate carboxykinase and glutaminase mRNAs in rat kidney and in LLC-PK-F+ cells Contributions to Nephrology. 92: 206-210. PMID 1756643 DOI: 10.1159/000420099 |
0.428 |
|
1991 |
Hwang JJ, Curthoys NP. Effect of acute alterations in acid-base balance on rat renal glutaminase and phosphoenolpyruvate carboxykinase gene expression Journal of Biological Chemistry. 266: 9392-9396. PMID 1709637 |
0.399 |
|
1991 |
Curthoys NP. Mechanism of altered renal glutaminase gene expression in response to chronic acidosis Biochemistry®. 30: 7522-7526. DOI: 10.1021/Bi00244A022 |
0.529 |
|
1988 |
Banner C, Hwang JJ, Shapiro RA, Wenthold RJ, Nakatani Y, Lampel KA, Thomas JW, Huie D, Curthoys NP. Isolation of a cDNA for rat brain glutaminase. Brain Research. 427: 247-54. PMID 3401701 DOI: 10.1016/0169-328X(88)90047-2 |
0.32 |
|
1988 |
Shapiro RA, Banner C, Hwang JJ, Wenthold RJ, Curthoys NP. Regulation of renal glutaminase gene expression during metabolic acidosis. Contributions to Nephrology. 63: 141-6. PMID 3191704 DOI: 10.1159/000415712 |
0.362 |
|
1987 |
Tong J, Shapiro RA, Curthoys NP. Changes in the levels of translatable glutaminase mRNA during onset and recovery from metabolic acidosis Biochemistry. 26: 2773-2777. DOI: 10.1021/Bi00384A018 |
0.497 |
|
1982 |
Curthoys NP, Shapiro RA. Mechanism of glutamate and alpha-ketoglutarate inhibition of rat renal phosphate-dependent glutaminase Contributions to Nephrology. 31: 71-76. PMID 6125340 DOI: 10.1159/000406618 |
0.314 |
|
1972 |
Curthoys NP, D'Ari Straus L, Rabinowitz JC. Formyltetrahydrofolate synthetase. Substrate binding to monomeric subunits. Biochemistry. 11: 345-9. PMID 5059116 DOI: 10.1021/Bi00753A006 |
0.546 |
|
1972 |
Curthoys NP, Rabinowitz JC. Formyltetrahydrofolate synthetase. Binding of folate substrates and kinetics of the reverse reaction. The Journal of Biological Chemistry. 247: 1965-71. PMID 5016638 |
0.484 |
|
1972 |
Curthoys NP, Scott JM, Rabinowitz JC. Folate coenzymes of Clostridium acidi-urici. The isolation of (l)-5,10-methenyltetrahydropteroyltriglutamate, its conversion to (l)-tetrahydropteroyltriglutamate and (l)-10-( 14 C)formyltetrahydropteroyltriglutamate, and the synthesis of (l)-10-formyl-(6,7- 3 H 2 )tetrahydropteroyltriglutamate and (l)-(6,7- 3 H 2 )tetrahydropteroyltriglutamate. The Journal of Biological Chemistry. 247: 1959-64. PMID 5016637 |
0.429 |
|
1971 |
Curthoys NP, Rabinowitz JC. Formyltetrahydrofolate synthetase. Binding of adenosine triphosphate and related ligands determined by partition equilibrium. The Journal of Biological Chemistry. 246: 6942-52. PMID 5126227 |
0.496 |
|
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