Phil Barker - Publications

Affiliations: 
Montreal Neurological Institute, McGill University, Montréal, Québec, Canada 

124 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Thomas RA, Ambalavanan A, Rouleau GA, Barker PA. Identification of genetic variants of LGI1 and RTN4R (NgR1) linked to schizophrenia that are defective in NgR1-LGI1 signaling. Molecular Genetics & Genomic Medicine. 4: 447-456. PMID 27468420 DOI: 10.1002/mgg3.215  0.56
2016 Danelon V, Montroull LE, Unsain N, Barker PA, Mascó DH. Calpain-dependent truncated form of TrkB-FL increases in neurodegenerative processes. Molecular and Cellular Neurosciences. PMID 27449758 DOI: 10.1016/j.mcn.2016.07.002  1
2016 Gibon J, Unsain N, Gamache K, Thomas RA, De Leon A, Johnstone A, Nader K, Séguéla P, Barker PA. The X-linked inhibitor of apoptosis regulates long-term depression and learning rate. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27189977 DOI: 10.1096/fj.201600384R  1
2016 Barker PM, Reid A, Schall MW. A framework for scaling up health interventions: lessons from large-scale improvement initiatives in Africa. Implementation Science : Is. 11: 12. PMID 26821910 DOI: 10.1186/s13012-016-0374-x  0.36
2015 Unsain N, Barker PA. New Views on the Misconstrued: Executioner Caspases and Their Diverse Non-apoptotic Roles. Neuron. 88: 461-74. PMID 26539888 DOI: 10.1016/j.neuron.2015.08.029  1
2015 Heard KN, Bertrand MJ, Barker PA. cIAP2 supports viability of mice lacking cIAP1 and XIAP. The Embo Journal. 34: 2393-5. PMID 26427758 DOI: 10.15252/embj.201592060  1
2015 Cueva Vargas JL, Osswald IK, Unsain N, Aurousseau MR, Barker PA, Bowie D, Di Polo A. Soluble Tumor Necrosis Factor Alpha Promotes Retinal Ganglion Cell Death in Glaucoma via Calcium-Permeable AMPA Receptor Activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 12088-102. PMID 26338321 DOI: 10.1523/JNEUROSCI.1273-15.2015  1
2015 Anastasia A, Barker PA, Chao MV, Hempstead BL. Detection of p75NTR Trimers: Implications for Receptor Stoichiometry and Activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 11911-20. PMID 26311773 DOI: 10.1523/JNEUROSCI.0591-15.2015  1
2015 Gibon J, Buckley SM, Unsain N, Kaartinen V, Séguéla P, Barker PA. proBDNF and p75NTR Control Excitability and Persistent Firing of Cortical Pyramidal Neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 9741-53. PMID 26134656 DOI: 10.1523/JNEUROSCI.4655-14.2015  1
2015 El-Sadr WM, Barker P, Rabkin M, Pillay Y, Birx D. Putting quality at the heart of HIV programs. Aids (London, England). 29: S119-20. PMID 26102621 DOI: 10.1097/QAD.0000000000000732  0.36
2015 Choe KY, Han SY, Gaub P, Shell B, Voisin DL, Knapp BA, Barker PA, Brown CH, Cunningham JT, Bourque CW. High salt intake increases blood pressure via BDNF-mediated downregulation of KCC2 and impaired baroreflex inhibition of vasopressin neurons. Neuron. 85: 549-60. PMID 25619659 DOI: 10.1016/j.neuron.2014.12.048  1
2015 Zeinieh M, Salehi A, Rajkumar V, Barker PA. p75NTR-dependent Rac1 activation requires receptor cleavage and activation of an NRAGE and NEDD9 signaling cascade. Journal of Cell Science. 128: 447-59. PMID 25472715 DOI: 10.1242/jcs.152173  1
2015 Schreij AM, Chaineau M, Ruan W, Lin S, Barker PA, Fon EA, McPherson PS. LRRK2 localizes to endosomes and interacts with clathrin-light chains to limit Rac1 activation. Embo Reports. 16: 79-86. PMID 25427558 DOI: 10.15252/embr.201438714  1
2015 Gibon J, Buckley SM, Unsain N, Kaartinen V, Séguéla P, Barker PA. proBDNF and p75NTR control excitability and persistent firing of cortical pyramidal neurons Journal of Neuroscience. 35: 9741-9753. DOI: 10.1523/JNEUROSCI.4655-14.2015  1
2014 Angelo MF, Aguirre A, Avilés Reyes RX, Villarreal A, Lukin J, Melendez M, Vanasco V, Barker P, Alvarez S, Epstein A, Jerusalinsky D, Ramos AJ. The proinflammatory RAGE/NF-κB pathway is involved in neuronal damage and reactive gliosis in a model of sleep apnea by intermittent hypoxia. Plos One. 9: e107901. PMID 25265561 DOI: 10.1371/journal.pone.0107901  1
2014 Cofie LE, Barrington C, Akaligaung A, Reid A, Fried B, Singh K, Sodzi-Tettey S, Barker PM. Integrating community outreach into a quality improvement project to promote maternal and child health in Ghana. Global Public Health. 9: 1184-97. PMID 25204848 DOI: 10.1080/17441692.2014.952656  0.36
2014 Unsain N, Heard KN, Higgins JM, Barker PA. Production and isolation of axons from sensory neurons for biochemical analysis using porous filters. Journal of Visualized Experiments : Jove. PMID 25046441 DOI: 10.3791/51795  1
2014 Villarreal A, Seoane R, González Torres A, Rosciszewski G, Angelo MF, Rossi A, Barker PA, Ramos AJ. S100B protein activates a RAGE-dependent autocrine loop in astrocytes: implications for its role in the propagation of reactive gliosis. Journal of Neurochemistry. PMID 24923428 DOI: 10.1111/jnc.12790  1
2014 Bush K, Thomas R, Raymond NT, Sankar S, Barker PJ, O'Hare JP. Cluster randomised controlled trial evaluation of a Link Worker-delivered intervention to improve uptake of diabetic retinopathy screening in a South Asian population. Diabetes & Vascular Disease Research. 11: 294-297. PMID 24845073 DOI: 10.1177/1479164114532964  0.6
2014 Afari H, Hirschhorn LR, Michaelis A, Barker P, Sodzi-Tettey S. Quality improvement in emergency obstetric referrals: qualitative study of provider perspectives in Assin North district, Ghana. Bmj Open. 4: e005052. PMID 24833695 DOI: 10.1136/bmjopen-2014-005052  0.36
2014 Ceni C, Unsain N, Zeinieh MP, Barker PA. Neurotrophins in the regulation of cellular survival and death. Handbook of Experimental Pharmacology. 220: 193-221. PMID 24668474 DOI: 10.1007/978-3-642-45106-5_8  1
2014 Forsyth PA, Krishna N, Lawn S, Valadez JG, Qu X, Fenstermacher DA, Fournier M, Potthast L, Chinnaiyan P, Gibney GT, Zeinieh M, Barker PA, Carter BD, Cooper MK, Kenchappa RS. p75 neurotrophin receptor cleavage by α- and γ-secretases is required for neurotrophin-mediated proliferation of brain tumor-initiating cells. The Journal of Biological Chemistry. 289: 8067-85. PMID 24519935 DOI: 10.1074/jbc.M113.513762  1
2014 Twum-Danso NA, Dasoberi IN, Amenga-Etego IA, Adondiwo A, Kanyoke E, Boadu RO, Atinbire S, Balagumyetime P, Bagni F, Kubio C, Sagoe-Moses I, Barker PM. Using quality improvement methods to test and scale up a new national policy on early post-natal care in Ghana. Health Policy and Planning. 29: 622-32. PMID 23894073 DOI: 10.1093/heapol/czt048  0.36
2013 Cresswell KM, Panesar SS, Salvilla SA, Carson-Stevens A, Larizgoitia I, Donaldson LJ, Bates D, Sheikh A. Global research priorities to better understand the burden of iatrogenic harm in primary care: an international Delphi exercise. Plos Medicine. 10: e1001554. PMID 24260028 DOI: 10.1371/journal.pmed.1001554  0.36
2013 Venter WD, Barker PM. Raising the CD4+ initiation threshold with our eyes wide open. South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde. 103: 834. PMID 24148179 DOI: 10.7196/SAMJ.7462  0.36
2013 Colbourn T, Nambiar B, Bondo A, Makwenda C, Tsetekani E, Makonda-Ridley A, Msukwa M, Barker P, Kotagal U, Williams C, Davies R, Webb D, Flatman D, Lewycka S, Rosato M, et al. Effects of quality improvement in health facilities and community mobilization through women's groups on maternal, neonatal and perinatal mortality in three districts of Malawi: MaiKhanda, a cluster randomized controlled effectiveness trial. International Health. 5: 180-95. PMID 24030269 DOI: 10.1093/inthealth/iht011  0.36
2013 Mate KS, Sifrim ZK, Chalkidou K, Cluzeau F, Cutler D, Kimball M, Morente T, Smits H, Barker P. Improving health system quality in low- and middle-income countries that are expanding health coverage: a framework for insurance. International Journal For Quality in Health Care : Journal of the International Society For Quality in Health Care / Isqua. 25: 497-504. PMID 23959955 DOI: 10.1093/intqhc/mzt053  0.36
2013 Unsain N, Higgins JM, Parker KN, Johnstone AD, Barker PA. XIAP regulates caspase activity in degenerating axons. Cell Reports. 4: 751-63. PMID 23954782 DOI: 10.1016/j.celrep.2013.07.015  1
2013 Singh K, Speizer I, Handa S, Boadu RO, Atinbire S, Barker PM, Twum-Danso NA. Impact evaluation of a quality improvement intervention on maternal and child health outcomes in Northern Ghana: early assessment of a national scale-up project. International Journal For Quality in Health Care : Journal of the International Society For Quality in Health Care / Isqua. 25: 477-87. PMID 23925506 DOI: 10.1093/intqhc/mzt054  0.36
2013 Mate KS, Ngubane G, Barker PM. A quality improvement model for the rapid scale-up of a program to prevent mother-to-child HIV transmission in South Africa. International Journal For Quality in Health Care : Journal of the International Society For Quality in Health Care / Isqua. 25: 373-80. PMID 23710069 DOI: 10.1093/intqhc/mzt039  0.36
2013 Methot L, Hermann R, Tang Y, Lo R, Al-Jehani H, Jhas S, Svoboda D, Slack RS, Barker PA, Stifani S. Interaction and antagonistic roles of NF-κB and Hes6 in the regulation of cortical neurogenesis. Molecular and Cellular Biology. 33: 2797-808. PMID 23689134 DOI: 10.1128/MCB.01610-12  1
2013 Ruan W, Unsain N, Desbarats J, Fon EA, Barker PA. Wengen, the sole tumour necrosis factor receptor in Drosophila, collaborates with moesin to control photoreceptor axon targeting during development. Plos One. 8: e60091. PMID 23544124 DOI: 10.1371/journal.pone.0060091  1
2013 Ngidi W, Reddy J, Luvuno Z, Rollins N, Barker P, Mate KS. Using a campaign approach among health workers to increase access to antiretroviral therapy for pregnant HIV-infected women in South Africa. Journal of Acquired Immune Deficiency Syndromes (1999). 63: e133-9. PMID 23514955 DOI: 10.1097/QAI.0b013e318291827f  0.36
2013 Wilson AM, Morquette B, Abdouh M, Unsain N, Barker PA, Feinstein E, Bernier G, Di Polo A. ASPP1/2 regulate p53-dependent death of retinal ganglion cells through PUMA and Fas/CD95 activation in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2205-16. PMID 23365256 DOI: 10.1523/JNEUROSCI.2635-12.2013  1
2013 Mate KS, Ngidi WH, Reddy J, Mphatswe W, Rollins N, Barker P. A case report of evaluating a large-scale health systems improvement project in an uncontrolled setting: a quality improvement initiative in KwaZulu-Natal, South Africa. Bmj Quality & Safety. 22: 891-8. PMID 23204513 DOI: 10.1136/bmjqs-2012-001244  0.36
2012 Massoud MR, Mensah-Abrampah N, Sax S, Leatherman S, Agins B, Barker P, Kelley E, Heiby JR, Lotherington J. Charting the way forward to better quality health care: how do we get there and what are the next steps? Recommendations from the Salzburg Global Seminar on making health care better in low- and middle-income economies. International Journal For Quality in Health Care : Journal of the International Society For Quality in Health Care / Isqua. 24: 558-63. PMID 23074182 DOI: 10.1093/intqhc/mzs062  0.36
2012 Maussion G, Yang J, Yerko V, Barker P, Mechawar N, Ernst C, Turecki G. Regulation of a truncated form of tropomyosin-related kinase B (TrkB) by Hsa-miR-185* in frontal cortex of suicide completers. Plos One. 7: e39301. PMID 22802923 DOI: 10.1371/journal.pone.0039301  1
2012 Massoud MR, Mensah-Abrampah N, Barker P, Leatherman S, Kelley E, Agins B, Sax S, Heiby J. Improving the delivery of safe and effective healthcare in low and middle income countries. Bmj (Clinical Research Ed.). 344: e981. PMID 22334574 DOI: 10.1136/bmj.e981  0.36
2012 Kenneth NS, Younger JM, Hughes ED, Marcotte D, Barker PA, Saunders TL, Duckett CS. An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1. The Biochemical Journal. 443: 355-9. PMID 22332634 DOI: 10.1042/BJ20120249  1
2011 Kommaddi RP, Thomas R, Ceni C, Daigneault K, Barker PA. Trk-dependent ADAM17 activation facilitates neurotrophin survival signaling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2061-70. PMID 21411748 DOI: 10.1096/fj.10-173740  1
2011 Kommaddi RP, Dickson KM, Barker PA. Stress-induced expression of the p75 neurotrophin receptor is regulated by O-GlcNAcylation of the Sp1 transcription factor. Journal of Neurochemistry. 116: 396-405. PMID 21105874 DOI: 10.1111/j.1471-4159.2010.07120.x  1
2011 Zhang Z, Reboreda A, Alonso A, Barker PA, Séguéla P. TRPC channels underlie cholinergic plateau potentials and persistent activity in entorhinal cortex. Hippocampus. 21: 386-97. PMID 20082292 DOI: 10.1002/hipo.20755  1
2010 Youngleson MS, Nkurunziza P, Jennings K, Arendse J, Mate KS, Barker P. Improving a mother to child HIV transmission programme through health system redesign: quality improvement, protocol adjustment and resource addition. Plos One. 5: e13891. PMID 21085479 DOI: 10.1371/journal.pone.0013891  0.36
2010 Bookman L, Engmann C, Srofenyoh E, Enweronu-Laryea C, Owen M, Randolph G, Price W, Barker P. Educational impact of a hospital-based neonatal resuscitation program in Ghana. Resuscitation. 81: 1180-2. PMID 20599314 DOI: 10.1016/j.resuscitation.2010.04.034  0.36
2010 Ceni C, Kommaddi RP, Thomas R, Vereker E, Liu X, McPherson PS, Ritter B, Barker PA. The p75NTR intracellular domain generated by neurotrophin-induced receptor cleavage potentiates Trk signaling. Journal of Cell Science. 123: 2299-307. PMID 20530577 DOI: 10.1242/jcs.062612  1
2010 Xu B, Goldman JS, Rymar VV, Forget C, Lo PS, Bull SJ, Vereker E, Barker PA, Trudeau LE, Sadikot AF, Kennedy TE. Critical roles for the netrin receptor deleted in colorectal cancer in dopaminergic neuronal precursor migration, axon guidance, and axon arborization. Neuroscience. 169: 932-49. PMID 20493932 DOI: 10.1016/j.neuroscience.2010.05.025  1
2010 Thomas R, Favell K, Morante-Redolat J, Pool M, Kent C, Wright M, Daignault K, Ferraro GB, Montcalm S, Durocher Y, Fournier A, Perez-Tur J, Barker PA. LGI1 is a Nogo receptor 1 ligand that antagonizes myelin-based growth inhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6607-12. PMID 20463223 DOI: 10.1523/JNEUROSCI.5147-09.2010  1
2010 Gauthier J, Champagne N, Lafrenière RG, Xiong L, Spiegelman D, Brustein E, Lapointe M, Peng H, Côté M, Noreau A, Hamdan FF, Addington AM, Rapoport JL, Delisi LE, Krebs MO, ... ... Barker PA, et al. De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. 107: 7863-8. PMID 20385823 DOI: 10.1073/pnas.0906232107  1
2010 Lebrun-Julien F, Bertrand MJ, De Backer O, Stellwagen D, Morales CR, Di Polo A, Barker PA. ProNGF induces TNFalpha-dependent death of retinal ganglion cells through a p75NTR non-cell-autonomous signaling pathway. Proceedings of the National Academy of Sciences of the United States of America. 107: 3817-22. PMID 20133718 DOI: 10.1073/pnas.0909276107  1
2009 Bertrand MJ, Doiron K, Labbé K, Korneluk RG, Barker PA, Saleh M. Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2. Immunity. 30: 789-801. PMID 19464198 DOI: 10.1016/j.immuni.2009.04.011  1
2009 Lebrun-Julien F, Duplan L, Pernet V, Osswald I, Sapieha P, Bourgeois P, Dickson K, Bowie D, Barker PA, Di Polo A. Excitotoxic death of retinal neurons in vivo occurs via a non-cell-autonomous mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 5536-45. PMID 19403821 DOI: 10.1523/JNEUROSCI.0831-09.2009  1
2009 Barker PA. A p75(NTR) pivoting paradigm propels perspicacity. Neuron. 62: 3-5. PMID 19376060 DOI: 10.1016/j.neuron.2009.04.005  1
2009 Snapyan M, Lemasson M, Brill MS, Blais M, Massouh M, Ninkovic J, Gravel C, Berthod F, Götz M, Barker PA, Parent A, Saghatelyan A. Vasculature guides migrating neuronal precursors in the adult mammalian forebrain via brain-derived neurotrophic factor signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 4172-88. PMID 19339612 DOI: 10.1523/JNEUROSCI.4956-08.2009  1
2009 Russo SJ, Wilkinson MB, Mazei-Robison MS, Dietz DM, Maze I, Krishnan V, Renthal W, Graham A, Birnbaum SG, Green TA, Robison B, Lesselyong A, Perrotti LI, Bolaños CA, Kumar A, ... ... Barker PA, et al. Nuclear factor kappa B signaling regulates neuronal morphology and cocaine reward. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 3529-37. PMID 19295158 DOI: 10.1523/JNEUROSCI.6173-08.2009  1
2009 Barker PA. Whither proBDNF? Nature Neuroscience. 12: 105-6. PMID 19172162 DOI: 10.1038/nn0209-105  1
2009 Angelo MF, Aviles-Reyes RX, Villarreal A, Barker P, Reines AG, Ramos AJ. p75 NTR expression is induced in isolated neurons of the penumbra after ischemia by cortical devascularization. Journal of Neuroscience Research. 87: 1892-903. PMID 19156869 DOI: 10.1002/jnr.21993  1
2009 Gushchina S, Leinster V, Wu D, Jasim A, Demestre M, Lopez de Heredia L, Michael GJ, Barker PA, Richardson PM, Magoulas C. Observations on the function of nuclear factor kappa B (NF-kappaB) in the survival of adult primary sensory neurons after nerve injury. Molecular and Cellular Neurosciences. 40: 207-16. PMID 19049877 DOI: 10.1016/j.mcn.2008.10.010  1
2008 Piton A, Michaud JL, Peng H, Aradhya S, Gauthier J, Mottron L, Champagne N, Lafrenière RG, Hamdan FF, Joober R, Fombonne E, Marineau C, Cossette P, Dubé MP, ... ... Barker PA, et al. Mutations in the calcium-related gene IL1RAPL1 are associated with autism. Human Molecular Genetics. 17: 3965-74. PMID 18801879 DOI: 10.1093/hmg/ddn300  1
2008 Bertrand MJ, Kenchappa RS, Andrieu D, Leclercq-Smekens M, Nguyen HN, Carter BD, Muscatelli F, Barker PA, De Backer O. NRAGE, a p75NTR adaptor protein, is required for developmental apoptosis in vivo. Cell Death and Differentiation. 15: 1921-9. PMID 18772898 DOI: 10.1038/cdd.2008.127  1
2008 Pispa J, Pummila M, Barker PA, Thesleff I, Mikkola ML. Edar and Troy signalling pathways act redundantly to regulate initiation of hair follicle development. Human Molecular Genetics. 17: 3380-91. PMID 18689798 DOI: 10.1093/hmg/ddn232  1
2008 Rumble JM, Bertrand MJ, Csomos RA, Wright CW, Albert L, Mak TW, Barker PA, Duckett CS. Apoptotic sensitivity of murine IAP-deficient cells. The Biochemical Journal. 415: 21-5. PMID 18684108 DOI: 10.1042/BJ20081188  1
2008 Bertrand MJ, Milutinovic S, Dickson KM, Ho WC, Boudreault A, Durkin J, Gillard JW, Jaquith JB, Morris SJ, Barker PA. cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination. Molecular Cell. 30: 689-700. PMID 18570872 DOI: 10.1016/j.molcel.2008.05.014  1
2008 Moore SW, Lai Wing Sun K, Xie F, Barker PA, Conti M, Kennedy TE. Soluble adenylyl cyclase is not required for axon guidance to netrin-1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 3920-4. PMID 18400890 DOI: 10.1523/JNEUROSCI.0547-08.2008  1
2008 Boutilier J, Ceni C, Pagdala PC, Forgie A, Neet KE, Barker PA. Proneurotrophins require endocytosis and intracellular proteolysis to induce TrkA activation. The Journal of Biological Chemistry. 283: 12709-16. PMID 18299325 DOI: 10.1074/jbc.M710018200  1
2007 Srinivasan B, Wang Z, Brun-Zinkernagel AM, Collier RJ, Black RA, Frank SJ, Barker PA, Roque RS. Photic injury promotes cleavage of p75NTR by TACE and nuclear trafficking of the p75 intracellular domain. Molecular and Cellular Neurosciences. 36: 449-61. PMID 17904861 DOI: 10.1016/j.mcn.2007.08.005  1
2007 Sossin WS, Barker PA. Something old, something new: BDNF-induced neuron survival requires TRPC channel function. Nature Neuroscience. 10: 537-8. PMID 17453053 DOI: 10.1038/nn0507-537  1
2007 Furuya K, Ozaki T, Hanamoto T, Hosoda M, Hayashi S, Barker PA, Takano K, Matsumoto M, Nakagawara A. Stabilization of p73 by nuclear IkappaB kinase-alpha mediates cisplatin-induced apoptosis. The Journal of Biological Chemistry. 282: 18365-78. PMID 17452332 DOI: 10.1074/jbc.M610522200  1
2007 Ramos A, Ho WC, Forte S, Dickson K, Boutilier J, Favell K, Barker PA. Hypo-osmolar stress induces p75NTR expression by activating Sp1-dependent transcription. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 1498-506. PMID 17287525 DOI: 10.1523/JNEUROSCI.4806-06.2007  1
2007 Barker PA. High affinity not in the vicinity? Neuron. 53: 1-4. PMID 17196523 DOI: 10.1016/j.neuron.2006.12.018  1
2006 Sirerol-Piquer MS, Ayerdi-Izquierdo A, Morante-Redolat JM, Herranz-Pérez V, Favell K, Barker PA, Pérez-Tur J. The epilepsy gene LGI1 encodes a secreted glycoprotein that binds to the cell surface. Human Molecular Genetics. 15: 3436-45. PMID 17067999 DOI: 10.1093/hmg/ddl421  1
2006 Kenchappa RS, Zampieri N, Chao MV, Barker PA, Teng HK, Hempstead BL, Carter BD. Ligand-dependent cleavage of the P75 neurotrophin receptor is necessary for NRIF nuclear translocation and apoptosis in sympathetic neurons. Neuron. 50: 219-32. PMID 16630834 DOI: 10.1016/j.neuron.2006.03.011  1
2006 Salehi AH, Morris SJ, Ho WC, Dickson KM, Doucet G, Milutinovic S, Durkin J, Gillard JW, Barker PA. AEG3482 is an antiapoptotic compound that inhibits Jun kinase activity and cell death through induced expression of heat shock protein 70. Chemistry & Biology. 13: 213-23. PMID 16492569 DOI: 10.1016/j.chembiol.2005.11.012  1
2005 Lora JM, Zhang DM, Liao SM, Burwell T, King AM, Barker PA, Singh L, Keaveney M, Morgenstern J, Gutiérrez-Ramos JC, Coyle AJ, Fraser CC. Tumor necrosis factor-alpha triggers mucus production in airway epithelium through an IkappaB kinase beta-dependent mechanism. The Journal of Biological Chemistry. 280: 36510-7. PMID 16123045 DOI: 10.1074/jbc.M507977200  1
2005 Makkerh JP, Ceni C, Auld DS, Vaillancourt F, Dorval G, Barker PA. p75 neurotrophin receptor reduces ligand-induced Trk receptor ubiquitination and delays Trk receptor internalization and degradation. Embo Reports. 6: 936-41. PMID 16113645 DOI: 10.1038/sj.embor.7400503  1
2005 Ceni C, Barker PA. Getting RIP'd stunts your growth Neuron. 46: 839-840. PMID 15953410 DOI: 10.1016/j.neuron.2005.06.002  1
2005 Ho WC, Dickson KM, Barker PA. Nuclear factor-kappaB induced by doxorubicin is deficient in phosphorylation and acetylation and represses nuclear factor-kappaB-dependent transcription in cancer cells. Cancer Research. 65: 4273-81. PMID 15899819 DOI: 10.1158/0008-5472.CAN-04-3494  1
2005 Barrett GL, Greferath U, Barker PA, Trieu J, Bennie A. Co-expression of the P75 neurotrophin receptor and neurotrophin receptor-interacting melanoma antigen homolog in the mature rat brain Neuroscience. 133: 381-392. PMID 15878242 DOI: 10.1016/j.neuroscience.2005.01.067  1
2004 Ormond J, Hislop J, Zhao Y, Webb N, Vaillaincourt F, Dyer JR, Ferraro G, Barker P, Martin KC, Sossin WS. ApTrkl, a Trk-like receptor, mediates serotonin- dependent ERK activation and long-term facilitation in Aplysia sensory neurons. Neuron. 44: 715-28. PMID 15541318 DOI: 10.1016/j.neuron.2004.11.001  1
2004 Becker EB, Howell J, Kodama Y, Barker PA, Bonni A. Characterization of the c-Jun N-terminal kinase-BimEL signaling pathway in neuronal apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8762-70. PMID 15470142 DOI: 10.1523/JNEUROSCI.2953-04.2004  1
2004 Dickson KM, Bhakar AL, Barker PA. TRAF6-dependent NF-kB transcriptional activity during mouse development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 231: 122-7. PMID 15305292 DOI: 10.1002/dvdy.20110  1
2004 Barker PA. p75NTR is positively promiscuous: Novel partners and new insights Neuron. 42: 529-533. PMID 15157416 DOI: 10.1016/j.neuron.2004.04.001  1
2004 Florez-McClure ML, Linseman DA, Chu CT, Barker PA, Bouchard RJ, Le SS, Laessig TA, Heidenreich KA. The p75 neurotrophin receptor can induce autophagy and death of cerebellar Purkinje neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4498-509. PMID 15140920 DOI: 10.1523/JNEUROSCI.5744-03.2004  1
2004 Bouchard JF, Moore SW, Tritsch NX, Roux PP, Shekarabi M, Barker PA, Kennedy TE. Protein kinase A activation promotes plasma membrane insertion of DCC from an intracellular pool: A novel mechanism regulating commissural axon extension. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3040-50. PMID 15044543 DOI: 10.1523/JNEUROSCI.4934-03.2004  1
2004 Paul CE, Vereker E, Dickson KM, Barker PA. A Pro-Apoptotic Fragment of the p75 Neurotrophin Receptor Is Expressed in p75NTRExonIV Null Mice Journal of Neuroscience. 24: 1917-1923. PMID 14985432 DOI: 10.1523/JNEUROSCI.5397-03.2004  1
2004 Gentry JJ, Barker PA, Carter BD. The p75 neurotrophin receptor: Multiple interactors and numerous functions Progress in Brain Research. 146: 25-39. PMID 14699954 DOI: 10.1016/S0079-6123(03)46002-0  1
2003 Bhakar AL, Howell JL, Paul CE, Salehi AH, Becker EB, Said F, Bonni A, Barker PA. Apoptosis induced by p75NTR overexpression requires Jun kinase-dependent phosphorylation of Bad. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 11373-81. PMID 14673001  1
2002 Roux PP, Dorval G, Boudreau M, Angers-Loustau A, Morris SJ, Makkerh J, Barker PA. K252a and CEP1347 are neuroprotective compounds that inhibit mixed-lineage kinase-3 and induce activation of Akt and ERK. The Journal of Biological Chemistry. 277: 49473-80. PMID 12388555 DOI: 10.1074/jbc.M203428200  1
2002 Salehi AH, Xanthoudakis S, Barker PA. NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway. The Journal of Biological Chemistry. 277: 48043-50. PMID 12376548 DOI: 10.1074/jbc.M205324200  1
2002 Bhakar AL, Tannis LL, Zeindler C, Russo MP, Jobin C, Park DS, MacPherson S, Barker PA. Constitutive nuclear factor-kappa B activity is required for central neuron survival. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8466-75. PMID 12351721  1
2002 Kendall SE, Goldhawk DE, Kubu C, Barker PA, Verdi JM. Expression analysis of a novel p75NTR signaling protein, which regulates cell cycle progression and apoptosis Mechanisms of Development. 117: 187-200. PMID 12204258 DOI: 10.1016/S0925-4773(02)00204-6  1
2002 Roux PP, Barker PA. Neurotrophin signaling through the p75 neurotrophin receptor. Progress in Neurobiology. 67: 203-33. PMID 12169297 DOI: 10.1016/S0301-0082(02)00016-3  1
2002 Barker PA, Hussain NK, McPherson PS. Retrograde signaling by the neurotrophins follows a well-worn trk. Trends in Neurosciences. 25: 379-81. PMID 12127743 DOI: 10.1016/S0166-2236(02)02199-9  1
2002 Barker PA, Salehi A. The MAGE proteins: emerging roles in cell cycle progression, apoptosis, and neurogenetic disease. Journal of Neuroscience Research. 67: 705-12. PMID 11891783 DOI: 10.1002/jnr.10160  1
2001 Roux PP, Bhakar AL, Kennedy TE, Barker PA. The p75 neurotrophin receptor activates Akt (protein kinase B) through a phosphatidylinositol 3-kinase-dependent pathway. The Journal of Biological Chemistry. 276: 23097-104. PMID 11312266 DOI: 10.1074/jbc.M011520200  1
2001 Wooten MW, Seibenhener ML, Mamidipudi V, Diaz-Meco MT, Barker PA, Moscat J. The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor. The Journal of Biological Chemistry. 276: 7709-12. PMID 11244088 DOI: 10.1074/jbc.C000869200  1
2000 Kryl D, Barker PA. TTIP is a novel protein that interacts with the truncated T1 TrkB neurotrophin receptor Biochemical and Biophysical Research Communications. 279: 925-930. PMID 11162451 DOI: 10.1006/bbrc.2000.4058  1
2000 Kubu CJ, Goldhawk DG, Barker PA, Verdi JM. Identification of the translational initiation codon in human MAGED1 Genomics. 70: 150-152. PMID 11087672 DOI: 10.1006/geno.2000.6356  1
2000 Salehi AH, Roux PP, Kubu CJ, Zeindler C, Bhakar A, Tannis LL, Verdi JM, Barker PA. NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis. Neuron. 27: 279-88. PMID 10985348  1
1999 Roux PP, Colicos MA, Barker PA, Kennedy TE. p75 neurotrophin receptor expression is induced in apoptotic neurons after seizure. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 6887-96. PMID 10436046  1
1999 Bhakar AL, Roux PP, Lachance C, Kryl D, Zeindler C, Barker PA. The p75 neurotrophin receptor (p75NTR) alters tumor necrosis factor-mediated NF-kappaB activity under physiological conditions, but direct p75NTR-mediated NF-kappaB activation requires cell stress. The Journal of Biological Chemistry. 274: 21443-9. PMID 10409708 DOI: 10.1074/jbc.274.30.21443  1
1999 Kryl D, Yacoubian T, Haapasalo A, Castren E, Lo D, Barker PA. Subcellular localization of full-length and truncated Trk receptor isoforms in polarized neurons and epithelial cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 5823-33. PMID 10407023  1
1999 MacPhee I, Barker PA. Extended ceramide exposure activates the trkA receptor by increasing receptor homodimer formation Journal of Neurochemistry. 72: 1423-1430. PMID 10098845 DOI: 10.1046/j.1471-4159.1999.721423.x  1
1998 Barker PA. p75(NTR): A study in contrasts Cell Death and Differentiation. 5: 346-356. PMID 10200483  1
1998 Becher B, Owens T, Antel JP, Barker PA. CD95-CD95L: Can the brain learn from the immune system? Trends in Neurosciences. 21: 114-117. PMID 9530918 DOI: 10.1016/S0166-2236(97)01180-6  1
1998 Ladiwala U, Lachance C, Simoneau SJJ, Bhakar A, Barker PA, Antel JP. p75 neurotrophin receptor expression on adult human oligodendrocytes: Signaling without cell death in response to NGF Journal of Neuroscience. 18: 1297-1304. PMID 9454839  1
1997 Lachance C, Belliveau DJ, Barker PA. Blocking nerve growth factor binding to the p75 neurotrophin receptor on sympathetic neurons transiently reduces trkA activation but does not affect neuronal survival Neuroscience. 81: 861-871. PMID 9316034 DOI: 10.1016/S0306-4522(97)00237-6  1
1997 MacPhee IJ, Barker PA. Brain-derived neurotrophic factor binding to the p75 neurotrophin receptor reduces TrkA signaling while increasing serine phosphorylation in the TrkA intracellular domain Journal of Biological Chemistry. 272: 23547-23551. PMID 9295291 DOI: 10.1074/jbc.272.38.23547  1
1997 Majdan M, Lachance C, Gloster A, Aloyz R, Zeindler C, Bamji S, Bhakar A, Belliveau D, Fawcett J, Miller FD, Barker PA. Transgenic mice expressing the intracellular domain of the p75 neurotrophin receptor undergo neuronal apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 6988-98. PMID 9278534  1
1996 D'Souza SD, Bonetti B, Balasingam V, Cashman NR, Barker PA, Troutt AB, Raine CS, Antel JP. Multiple sclerosis: Fas signaling in oligodendrocyte cell death. The Journal of Experimental Medicine. 184: 2361-70. PMID 8976190 DOI: 10.1084/jem.184.6.2361  1
1994 Barker PA, Barbee G, Misko TP, Shooter EM. The low affinity neurotrophin receptor, p75LNTR, is palmitoylated by thioester formation through cysteine 279. The Journal of Biological Chemistry. 269: 30645-50. PMID 7982984  1
1994 Kahle P, Barker PA, Shooter EM, Hertel C. p75 nerve growth factor receptor modulates p140trkA kinase activity, but not ligand internalization, in PC12 cells. Journal of Neuroscience Research. 38: 599-606. PMID 7815475 DOI: 10.1002/jnr.490380512  1
1994 Barker PA, Shooter EM. Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cells. Neuron. 13: 203-15. PMID 7519025 DOI: 10.1016/0896-6273(94)90470-7  1
1993 Murphy RA, Acheson A, Hodges R, Haskins J, Richards C, Reklow E, Chlumecky V, Barker PA, Alderson RF, Lindsay RM. Immunological relationships of NGF, BDNF, and NT-3: recognition and functional inhibition by antibodies to NGF. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 2853-62. PMID 8331376  1
1993 Barker PA, Lomen-Hoerth C, Gensch EM, Meakin SO, Glass DJ, Shooter EM. Tissue-specific alternative splicing generates two isoforms of the trkA receptor. The Journal of Biological Chemistry. 268: 15150-7. PMID 8325889  1
1993 Drinkwater CC, Barker PA, Suter U, Shooter EM. The carboxyl terminus of nerve growth factor is required for biological activity. The Journal of Biological Chemistry. 268: 23202-7. PMID 8226840  1
1992 Ramsden CA, Markiewicz M, Walters DV, Gabella G, Parker KA, Barker PM, Neil HL. Liquid flow across the epithelium of the artificially perfused lung of fetal and postnatal sheep. The Journal of Physiology. 448: 579-97. PMID 1593479  0.36
1992 Barker P, Miller F, Murphy R. Analysis of NGF receptor gene products: Generation of artifactual splice variants by PCR Biotechniques. 12: 216+218. PMID 1377477  1
1992 Toma JG, Pareek S, Barker P, Mathew TC, Murphy RA, Acheson A, Miller FD. Spatiotemporal increases in epidermal growth factor receptors following peripheral nerve injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 2504-15. PMID 1377231  1
1992 Barker PA, Murphy RA. The nerve growth factor receptor: a multicomponent system that mediates the actions of the neurotrophin family of proteins. Molecular and Cellular Biochemistry. 110: 1-15. PMID 1315923 DOI: 10.1007/BF02385000  1
1991 Acheson A, Barker PA, Alderson RF, Miller FD, Murphy RA. Detection of brain-derived neurotrophic factor-like activity in fibroblasts and Schwann cells: inhibition by antibodies to NGF. Neuron. 7: 265-75. PMID 1873030 DOI: 10.1016/0896-6273(91)90265-2  1
1991 Barker PA, Miller FD, Large TH, Murphy RA. Generation of the truncated form of the nerve growth factor receptor by rat Schwann cells. Evidence for post-translational processing. The Journal of Biological Chemistry. 266: 19113-9. PMID 1655773  1
1990 Barker PM, Markiewicz M, Parker KA, Walters DV, Strang LB. Synergistic action of triiodothyronine and hydrocortisone on epinephrine-induced reabsorption of fetal lung liquid. Pediatric Research. 27: 588-91. PMID 2356103 DOI: 10.1203/00006450-199006000-00010  0.36
1989 Murphy RA, Chlumecky V, Smillie LB, Carpenter M, Nattriss M, Anderson JK, Rhodes JA, Barker PA, Siminoski K, Campenot RB. Isolation and characterization of a glycosylated form of beta nerve growth factor in mouse submandibular glands. The Journal of Biological Chemistry. 264: 12502-9. PMID 2745457  1
1988 Barker PA, Gilchrist JS, Belcastro AN. An improved method for the isolation of rat cardiac sarcoplasmic reticulum Molecular and Cellular Biochemistry. 84: 87-95. PMID 2976479 DOI: 10.1007/BF00235196  1
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