Nathan Dascal - Publications

Affiliations: 
Tel Aviv University, Tel Aviv-Yafo, Tel Aviv District, Israel 
Area:
potassium channel

140 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Colombo S, Reddy HP, Petri S, Williams DJ, Shalomov B, Dhindsa RS, Gelfman S, Krizay D, Bera AK, Yang M, Peng Y, Makinson CD, Boland MJ, Frankel WN, Goldstein DB, ... Dascal N, et al. Epilepsy in a mouse model of GNB1 encephalopathy arises from altered potassium (GIRK) channel signaling and is alleviated by a GIRK inhibitor. Frontiers in Cellular Neuroscience. 17: 1175895. PMID 37275776 DOI: 10.3389/fncel.2023.1175895  0.814
2022 Cui M, Xu K, Gada K, Shalomov B, Ban M, Eptaminitaki GC, Kawano T, Plant LD, Dascal N, Logothetis DE. A novel small molecule selective activator of homomeric GIRK4 channels. The Journal of Biological Chemistry. 102009. PMID 35525275 DOI: 10.1016/j.jbc.2022.102009  0.489
2022 Friesacher T, Reddy HP, Bernsteiner H, Carlo Combista J, Shalomov B, Bera AK, Zangerl-Plessl EM, Dascal N, Stary-Weinzinger A. A selectivity filter mutation provides insights into gating regulation of a K channel. Communications Biology. 5: 345. PMID 35411015 DOI: 10.1038/s42003-022-03303-1  0.82
2021 Shalomov B, Handklo-Jamal R, Reddy HP, Theodor N, Bera AK, Dascal N. A revised mechanism of action of hyperaldosteronism-linked mutations in cytosolic domains of GIRK4 (KCNJ5). The Journal of Physiology. PMID 34957562 DOI: 10.1113/JP282690  0.795
2021 Reddy HP, Yakubovich D, Keren-Raifman T, Tabak G, Tsemakhovich VA, Pedersen MH, Shalomov B, Colombo S, Goldstein DB, Javitch JA, Bera AK, Dascal N. Encephalopathy-causing mutations in Gβ () alter regulation of neuronal GIRK channels. Iscience. 24: 103018. PMID 34522861 DOI: 10.1016/j.isci.2021.103018  0.834
2020 Berlin S, Artzy E, Handklo-Jamal R, Kahanovitch U, Parnas H, Dascal N, Yakubovich D. A Collision Coupling Model Governs the Activation of Neuronal GIRK1/2 Channels by Muscarinic-2 Receptors. Frontiers in Pharmacology. 11: 1216. PMID 32903404 DOI: 10.3389/Fphar.2020.01216  0.841
2020 Handklo-Jamal R, Meisel E, Yakubovich D, Vysochek L, Beinart R, Glikson M, McMullen JR, Dascal N, Nof E, Oz S. Andersen-Tawil Syndrome Is Associated With Impaired PIP Regulation of the Potassium Channel Kir2.1. Frontiers in Pharmacology. 11: 672. PMID 32499698 DOI: 10.3389/Fphar.2020.00672  0.508
2020 Jamal RH, Shalomov B, Reddy HP, Theodor N, Ashkar M, Bera AK, Dascal N. Cellular and Functional Defects in Aldosteronism-linked Cytosolic Domain Mutations in GIRK4 (KCNJ5) Biophysical Journal. 118: 117a. DOI: 10.1016/J.Bpj.2019.11.780  0.746
2020 Shalomov B, Dabbah S, Dascal N. Antiepileptic Drug Ethosuximide May Regulate Absence Seizures Through Different Ion Channels Biophysical Journal. 118: 588a. DOI: 10.1016/J.Bpj.2019.11.3189  0.369
2020 Yakubovich D, Kahanovitch U, Tabak G, Keren Raifman T, Tsemakhovich V, Ranjan Tripathy D, Dessauer CW, Hirsch JA, Dascal N. Gβγ Activates GIRK2 with Low-Micromolar Affinity with Distinct Activation Pattern Compared to GIRK1/2 Biophysical Journal. 118: 270a. DOI: 10.1016/J.Bpj.2019.11.1557  0.749
2019 Tabak G, Keren-Raifman T, Kahanovitch U, Dascal N. Mutual action by Gγ and Gβ for optimal activation of GIRK channels in a channel subunit-specific manner. Scientific Reports. 9: 508. PMID 30679535 DOI: 10.1038/S41598-018-36833-Y  0.847
2017 Raifman TK, Kumar P, Haase H, Klussmann E, Dascal N, Weiss S. Protein kinase C enhances plasma membrane expression of cardiac L-type calcium channel, CaV1.2. Channels (Austin, Tex.). 0. PMID 28901828 DOI: 10.1080/19336950.2017.1369636  0.358
2017 Dascal N, Rubinstein M. Lithium reduces the span of G protein-activated K(+) (GIRK) channel inhibition in hippocampal neurons. Bipolar Disorders. PMID 28895268 DOI: 10.1111/Bdi.12536  0.538
2017 Kahanovitch U, Berlin S, Dascal N. Collision coupling in the GABAB receptor - G protein - GIRK signaling cascade. Febs Letters. PMID 28724189 DOI: 10.1002/1873-3468.12756  0.797
2017 Shalomov B, Reddy HP, Kanti Bera A, Dascal N. GIRK4 Mutations R52H and E246K Impair Channel Gating but not Inward Rectification Biophysical Journal. 112: 173a. DOI: 10.1016/J.Bpj.2016.11.959  0.837
2016 Guggenheimer AB, Almagor L, Tsemakhovich V, Ranjan Tripathy D, Hirsch J, Dascal N. Direct Interaction Between N and C Termini of α1C Subunit of CaV1.2 L-Type Calcium Channel Biophysical Journal. 110: 443a. DOI: 10.1016/J.Bpj.2015.11.2386  0.462
2015 Benmocha Guggenheimer A, Almagor L, Tsemakhovich V, Tripathy DR, Hirsch JA, Dascal N. Interactions between N and C termini of α1C subunit regulate inactivation of CaV1.2 L-type Ca(2+) channel. Channels (Austin, Tex.). 0. PMID 26577286 DOI: 10.1080/19336950.2015.1108499  0.457
2015 Yakubovich D, Berlin S, Kahanovitch U, Rubinstein M, Farhy-Tselnicker I, Styr B, Keren-Raifman T, Dessauer CW, Dascal N. A Quantitative Model of the GIRK1/2 Channel Reveals That Its Basal and Evoked Activities Are Controlled by Unequal Stoichiometry of Gα and Gβγ. Plos Computational Biology. 11: e1004598. PMID 26544551 DOI: 10.1371/Journal.Pcbi.1004598  0.799
2015 Dascal N, Kahanovitch U. The Roles of Gβγ and Gα in Gating and Regulation of GIRK Channels. International Review of Neurobiology. 123: 27-85. PMID 26422982 DOI: 10.1016/Bs.Irn.2015.06.001  0.839
2015 Weiss S, Dascal N. Molecular Aspects of Modulation of L-type Calcium Channels by Protein Kinase C. Current Molecular Pharmacology. PMID 25966700  0.429
2014 Kahanovitch U, Tsemakhovich V, Berlin S, Rubinstein M, Styr B, Castel R, Peleg S, Tabak G, Dessauer CW, Ivanina T, Dascal N. Recruitment of Gβγ controls the basal activity of G-protein coupled inwardly rectifying potassium (GIRK) channels: crucial role of distal C terminus of GIRK1. The Journal of Physiology. 592: 5373-90. PMID 25384780 DOI: 10.1113/Jphysiol.2014.283218  0.845
2014 Farhy Tselnicker I, Tsemakhovich V, Rishal I, Kahanovitch U, Dessauer CW, Dascal N. Dual regulation of G proteins and the G-protein-activated K+ channels by lithium. Proceedings of the National Academy of Sciences of the United States of America. 111: 5018-23. PMID 24639496 DOI: 10.1073/Pnas.1316425111  0.824
2014 Edelheit O, Ben-Shahar R, Dascal N, Hanukoglu A, Hanukoglu I. Conserved charged residues at the surface and interface of epithelial sodium channel subunits--roles in cell surface expression and the sodium self-inhibition response. The Febs Journal. 281: 2097-111. PMID 24571549 DOI: 10.1111/Febs.12765  0.463
2014 Yakubovich D, Dascal N. Subunit Composition Determines Gβγ Activation of Single Girk Channels Biophysical Journal. 106: 543a. DOI: 10.1016/J.Bpj.2013.11.3025  0.528
2014 Tselnicker IF, Tsemakhovich V, Rishal I, Dessauer CW, Dascal N. Dual Regulation of G Proteins and the G Protein-Activated Potassium Channels (GIRK) by Lithium Biophysical Journal. 106: 433a. DOI: 10.1016/J.Bpj.2013.11.2436  0.548
2013 Weiss S, Oz S, Benmocha A, Dascal N. Regulation of cardiac L-type Ca²⁺ channel CaV1.2 via the β-adrenergic-cAMP-protein kinase A pathway: old dogmas, advances, and new uncertainties. Circulation Research. 113: 617-31. PMID 23948586 DOI: 10.1161/CIRCRESAHA.113.301781  0.375
2013 Edvardson S, Oz S, Abulhijaa FA, Taher FB, Shaag A, Zenvirt S, Dascal N, Elpeleg O. Early infantile epileptic encephalopathy associated with a high voltage gated calcium channelopathy. Journal of Medical Genetics. 50: 118-23. PMID 23339110 DOI: 10.1136/jmedgenet-2012-101223  0.354
2013 Treiber F, Rosker C, Keren-Raifman T, Steinecker B, Gorischek A, Dascal N, Schreibmayer W. Molecular basis of the facilitation of the heterooligomeric GIRK1/GIRK4 complex by cAMP dependent protein kinase. Biochimica Et Biophysica Acta. 1828: 1214-21. PMID 23305758 DOI: 10.1016/j.bbamem.2012.12.016  0.447
2012 Weiss S, Keren-Raifman T, Oz S, Ben Mocha A, Haase H, Dascal N. Modulation of distinct isoforms of L-type calcium channels by G(q)-coupled receptors in Xenopus oocytes: antagonistic effects of Gβγ and protein kinase C. Channels (Austin, Tex.). 6: 426-37. PMID 22990911 DOI: 10.4161/Chan.22016  0.476
2012 Oz S, Benmocha A, Dascal N. CaBP1 and Calmodulin Compete in Regulating Calcium-Dependent Inactivation of CaV1.2 Biophysical Journal. 102: 125a. DOI: 10.1016/J.Bpj.2011.11.698  0.383
2012 Yakubovich D, Berlin S, Rubinstein M, Kahanovich U, Dessauer CW, Dascal N. Preferential Association with Gβγ Over Gα Governs the Activity of a G Protein-Activated K+ Channel Biophysical Journal. 102: 538a. DOI: 10.1016/J.Bpj.2011.11.2939  0.559
2011 Berlin S, Tsemakhovich VA, Castel R, Ivanina T, Dessauer CW, Keren-Raifman T, Dascal N. Two distinct aspects of coupling between Gα(i) protein and G protein-activated K+ channel (GIRK) revealed by fluorescently labeled Gα(i3) protein subunits. The Journal of Biological Chemistry. 286: 33223-35. PMID 21795707 DOI: 10.1074/Jbc.M111.271056  0.439
2011 Edelheit O, Hanukoglu I, Dascal N, Hanukoglu A. Identification of the roles of conserved charged residues in the extracellular domain of an epithelial sodium channel (ENaC) subunit by alanine mutagenesis. American Journal of Physiology. Renal Physiology. 300: F887-97. PMID 21209000 DOI: 10.1152/Ajprenal.00648.2010  0.327
2011 Berlin S, Tsemakhovich V, Dessauer CW, Dascal N. Deficient Regulation of Gbetagamma Effectors by Fluorescently Labeled Galpha i3 Subunits Reveals Distinct Aspects of Coupling to GIRK and Cav2.2 Channels Biophysical Journal. 100: 258a. DOI: 10.1016/J.Bpj.2010.12.1624  0.554
2010 Tselnicker I, Dascal N. Further characterization of regulation of Ca(V)2.2 by stargazin. Channels (Austin, Tex.). 4: 351-4. PMID 21139418 DOI: 10.4161/Chan.4.5.13504  0.556
2010 Laish-Farkash A, Glikson M, Brass D, Marek-Yagel D, Pras E, Dascal N, Antzelevitch C, Nof E, Reznik H, Eldar M, Luria D. A novel mutation in the HCN4 gene causes symptomatic sinus bradycardia in Moroccan Jews. Journal of Cardiovascular Electrophysiology. 21: 1365-72. PMID 20662977 DOI: 10.1111/j.1540-8167.2010.01844.x  0.368
2010 Tselnicker I, Tsemakhovich VA, Dessauer CW, Dascal N. Stargazin modulates neuronal voltage-dependent Ca(2+) channel Ca(v)2.2 by a Gbetagamma-dependent mechanism. The Journal of Biological Chemistry. 285: 20462-71. PMID 20435886 DOI: 10.1074/Jbc.M110.121277  0.42
2010 Babai N, Kanevsky N, Dascal N, Rozanski GJ, Singh DP, Fatma N, Thoreson WB. Anion-sensitive regions of L-type CaV1.2 calcium channels expressed in HEK293 cells. Plos One. 5: e8602. PMID 20066046 DOI: 10.1371/Journal.Pone.0008602  0.359
2010 Edelheit O, Hanukoglu I, Shriki Y, Tfilin M, Dascal N, Gillis D, Hanukoglu A. Truncated beta epithelial sodium channel (ENaC) subunits responsible for multi-system pseudohypoaldosteronism support partial activity of ENaC. The Journal of Steroid Biochemistry and Molecular Biology. 119: 84-8. PMID 20064610 DOI: 10.1016/J.Jsbmb.2010.01.002  0.443
2010 Oz S, Benmocha A, Lee A, Dascal N. CaBP1 Regulates Both Ca and Ba currents through Ca(v)1.2 (L-type) Calcium Channels Biophysical Journal. 98: 693a. DOI: 10.1016/J.Bpj.2009.12.3808  0.403
2010 Yakubovich D, Berlin S, Dascal N. Mathematical Model of Basal and Agonist-Dependent GIRK Channel Activity Biophysical Journal. 98: 495a. DOI: 10.1016/J.Bpj.2009.12.2696  0.567
2010 Berlin S, Yakubovich D, Keren-Raifman T, Dascal N. The Human Muscarinic Receptor Couples to GαI3 Via Catalytic Collision Biophysical Journal. 98: 291a. DOI: 10.1016/J.Bpj.2009.12.1584  0.5
2009 Sadana R, Dascal N, Dessauer CW. N terminus of type 5 adenylyl cyclase scaffolds Gs heterotrimer. Molecular Pharmacology. 76: 1256-64. PMID 19783621 DOI: 10.1124/Mol.109.058370  0.38
2009 Rubinstein M, Peleg S, Berlin S, Brass D, Keren-Raifman T, Dessauer CW, Ivanina T, Dascal N. Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K+ channel by GalphaiGDP and Gbetagamma. The Journal of Physiology. 587: 3473-91. PMID 19470775 DOI: 10.1113/Jphysiol.2009.173229  0.625
2009 Yakubovich D, Rishal I, Dessauer CW, Dascal N. Amplitude histogram-based method of analysis of patch clamp recordings that involve extreme changes in channel activity levels. Journal of Molecular Neuroscience : Mn. 37: 201-11. PMID 18622586 DOI: 10.1007/S12031-008-9117-Z  0.545
2009 Berlin S, Keren-Raifman T, Rubinstein M, Ivanina T, Dascal N. Both “Constitutively-active” and “Inactive” Gαi3 Mutants Interact with GIRK1/2 Heterotetramer Biophysical Journal. 96: 464a. DOI: 10.1016/J.Bpj.2008.12.2389  0.603
2009 Rubinstein M, Berlin S, Keren-Raifman T, Peleg S, Dessauer C, Ivanina T, Dascal N. Diverse Regulation of the Neuronal G-Protein Gated K+ Channel (GIRK), GIRK1 and GIRK2 by Gα and Gβγ Biophysical Journal. 96: 464a. DOI: 10.1016/J.Bpj.2008.12.2388  0.625
2008 Hanukoglu A, Edelheit O, Shriki Y, Gizewska M, Dascal N, Hanukoglu I. Renin-aldosterone response, urinary Na/K ratio and growth in pseudohypoaldosteronism patients with mutations in epithelial sodium channel (ENaC) subunit genes. The Journal of Steroid Biochemistry and Molecular Biology. 111: 268-74. PMID 18634878 DOI: 10.1016/J.Jsbmb.2008.06.013  0.375
2008 Kupchik YM, Rashkovan G, Ohana L, Keren-Raifman T, Dascal N, Parnas H, Parnas I. Molecular mechanisms that control initiation and termination of physiological depolarization-evoked transmitter release. Proceedings of the National Academy of Sciences of the United States of America. 105: 4435-40. PMID 18326630 DOI: 10.1073/Pnas.0708540105  0.332
2007 Gibor G, Yakubovich D, Rosenhouse-Dantsker A, Peretz A, Schottelndreier H, Seebohm G, Dascal N, Logothetis DE, Paas Y, Attali B. An inactivation gate in the selectivity filter of KCNQ1 potassium channels. Biophysical Journal. 93: 4159-72. PMID 17704175 DOI: 10.1529/Biophysj.107.107987  0.423
2007 Nof E, Luria D, Brass D, Marek D, Lahat H, Reznik-Wolf H, Pras E, Dascal N, Eldar M, Glikson M. Point mutation in the HCN4 cardiac ion channel pore affecting synthesis, trafficking, and functional expression is associated with familial asymptomatic sinus bradycardia. Circulation. 116: 463-70. PMID 17646576 DOI: 10.1161/Circulationaha.107.706887  0.492
2007 Rubinstein M, Peleg S, Berlin S, Brass D, Dascal N. Galphai3 primes the G protein-activated K+ channels for activation by coexpressed Gbetagamma in intact Xenopus oocytes. The Journal of Physiology. 581: 17-32. PMID 17289785 DOI: 10.1113/Jphysiol.2006.125864  0.604
2006 Ben-Chaim Y, Chanda B, Dascal N, Bezanilla F, Parnas I, Parnas H. Movement of 'gating charge' is coupled to ligand binding in a G-protein-coupled receptor. Nature. 444: 106-9. PMID 17065983 DOI: 10.1038/Nature05259  0.429
2006 Kanevsky N, Dascal N. Regulation of maximal open probability is a separable function of Ca(v)beta subunit in L-type Ca2+ channel, dependent on NH2 terminus of alpha1C (Ca(v)1.2alpha). The Journal of General Physiology. 128: 15-36. PMID 16801381 DOI: 10.1085/Jgp.200609485  0.392
2006 Uezono Y, Kanaide M, Kaibara M, Barzilai R, Dascal N, Sumikawa K, Taniyama K. Coupling of GABAB receptor GABAB2 subunit to G proteins: evidence from Xenopus oocyte and baby hamster kidney cell expression system. American Journal of Physiology. Cell Physiology. 290: C200-7. PMID 16120656 DOI: 10.1152/Ajpcell.00269.2005  0.49
2005 Yakubovich D, Rishal I, Dascal N. Kinetic modeling of Na(+)-induced, Gbetagamma-dependent activation of G protein-gated K(+) channels. Journal of Molecular Neuroscience : Mn. 25: 7-19. PMID 15781962 DOI: 10.1385/Jmn:25:1:007  0.556
2005 Rishal I, Porozov Y, Yakubovich D, Varon D, Dascal N. Gbetagamma-dependent and Gbetagamma-independent basal activity of G protein-activated K+ channels. The Journal of Biological Chemistry. 280: 16685-94. PMID 15728579 DOI: 10.1074/Jbc.M412196200  0.522
2004 Dhingra A, Faurobert E, Dascal N, Sterling P, Vardi N. A retinal-specific regulator of G-protein signaling interacts with Galpha(o) and accelerates an expressed metabotropic glutamate receptor 6 cascade. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5684-93. PMID 15215290 DOI: 10.1523/Jneurosci.0492-04.2004  0.328
2004 Itzhaki Van-Ham I, Peleg S, Dascal N, Shapira H, Oron Y. G protein-activated K+ channels: a reporter for rapid activation of G proteins by lysophosphatidic acid in Xenopus oocytes. Febs Letters. 564: 157-60. PMID 15094059 DOI: 10.1016/S0014-5793(04)00334-5  0.535
2004 Ivanina T, Varon D, Peleg S, Rishal I, Porozov Y, Dessauer CW, Keren-Raifman T, Dascal N. Galphai1 and Galphai3 differentially interact with, and regulate, the G protein-activated K+ channel. The Journal of Biological Chemistry. 279: 17260-8. PMID 14963032 DOI: 10.1074/Jbc.M313425200  0.514
2004 Blumenstein Y, Maximyuk OP, Lozovaya N, Yatsenko NM, Kanevsky N, Krishtal O, Dascal N. Intracellular Na+ inhibits voltage-dependent N-type Ca2+ channels by a G protein betagamma subunit-dependent mechanism. The Journal of Physiology. 556: 121-34. PMID 14742725 DOI: 10.1113/Jphysiol.2003.056168  0.459
2004 Weiss S, Doan T, Bernstein KE, Dascal N. Modulation of cardiac Ca2+ channel by Gq-activating neurotransmitters reconstituted in Xenopus oocytes. The Journal of Biological Chemistry. 279: 12503-10. PMID 14722109 DOI: 10.1074/Jbc.M310196200  0.402
2003 Ivanina T, Rishal I, Varon D, Mullner C, Frohnwieser-Steinecke B, Schreibmayer W, Dessauer CW, Dascal N. Mapping the Gbetagamma-binding sites in GIRK1 and GIRK2 subunits of the G protein-activated K+ channel. The Journal of Biological Chemistry. 278: 29174-83. PMID 12743112 DOI: 10.1074/Jbc.M304518200  0.464
2003 Ben-Chaim Y, Tour O, Dascal N, Parnas I, Parnas H. The M2 muscarinic G-protein-coupled receptor is voltage-sensitive. The Journal of Biological Chemistry. 278: 22482-91. PMID 12684524 DOI: 10.1074/Jbc.M301146200  0.488
2003 Rishal I, Keren-Raifman T, Yakubovich D, Ivanina T, Dessauer CW, Slepak VZ, Dascal N. Na+ promotes the dissociation between Galpha GDP and Gbeta gamma, activating G protein-gated K+ channels. The Journal of Biological Chemistry. 278: 3840-5. PMID 12488455 DOI: 10.1074/Jbc.C200605200  0.497
2002 Peleg S, Varon D, Ivanina T, Dessauer CW, Dascal N. G(alpha)(i) controls the gating of the G protein-activated K(+) channel, GIRK. Neuron. 33: 87-99. PMID 11779482 DOI: 10.1016/S0896-6273(01)00567-0  0.439
2002 Maximyuk O, Khmyz V, Lozovaya N, Dascal N, Krishtal O. Na+ influx inhibits neuronal Ca2+ channels Neurophysiology. 34: 182-183. DOI: 10.1023/A:1020747131908  0.451
2001 Dascal N. Voltage clamp recordings from Xenopus oocytes. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 6.12. PMID 18428511 DOI: 10.1002/0471142301.Ns0612S10  0.485
2001 Dascal N. Ion-channel regulation by G proteins. Trends in Endocrinology and Metabolism: Tem. 12: 391-8. PMID 11595540 DOI: 10.1016/S1043-2760(01)00475-1  0.566
2001 Keren-Raifman T, Bera AK, Zveig D, Peleg S, Witherow DS, Slepak VZ, Dascal N. Expression levels of RGS7 and RGS4 proteins determine the mode of regulation of the G protein-activated K(+) channel and control regulation of RGS7 by G beta 5. Febs Letters. 492: 20-8. PMID 11248230 DOI: 10.1016/S0014-5793(01)02220-7  0.744
2000 Ivanina T, Blumenstein Y, Shistik E, Barzilai R, Dascal N. Modulation of L-type Ca2+ channels by gbeta gamma and calmodulin via interactions with N and C termini of alpha 1C. The Journal of Biological Chemistry. 275: 39846-54. PMID 10995757 DOI: 10.1074/Jbc.M005881200  0.452
2000 Singer-Lahat D, Dascal N, Mittelman L, Peleg S, Lotan I. Imaging plasma membrane proteins in large membrane patches of Xenopus oocytes. Pflã¼Gers Archiv : European Journal of Physiology. 440: 627-33. PMID 10958347 DOI: 10.1007/S004240000341  0.333
2000 Keren-Raifman T, Ivanina T, Bismuth Y, Dascal N. Expression cloning of KCRF, a potassium channel regulatory factor. Biochemical and Biophysical Research Communications. 274: 852-8. PMID 10924366 DOI: 10.1006/Bbrc.2000.3240  0.43
2000 Yakubovich D, Pastushenko V, Bitler A, Dessauer CW, Dascal N. Slow modal gating of single G protein-activated K+ channels expressed in Xenopus oocytes. The Journal of Physiology. 524: 737-55. PMID 10790155 DOI: 10.1111/J.1469-7793.2000.00737.X  0.574
2000 Müllner C, Vorobiov D, Bera AK, Uezono Y, Yakubovich D, Frohnwieser-Steinecker B, Dascal N, Schreibmayer W. Heterologous facilitation of G protein-activated K(+) channels by beta-adrenergic stimulation via cAMP-dependent protein kinase. The Journal of General Physiology. 115: 547-58. PMID 10779313 DOI: 10.1085/Jgp.115.5.547  0.733
2000 Vorobiov D, Bera AK, Keren-Raifman T, Barzilai R, Dascal N. Coupling of the muscarinic m2 receptor to G protein-activated K(+) channels via Galpha(z) and a receptor-Galpha(z) fusion protein. Fusion between the receptor and Galpha(z) eliminates catalytic (collision) coupling. The Journal of Biological Chemistry. 275: 4166-70. PMID 10660578 DOI: 10.1074/Jbc.275.6.4166  0.732
1999 Singer-Lahat D, Dascal N, Lotan I. Modal behavior of the Kv1.1 channel conferred by the Kvbeta1.1 subunit and its regulation by dephosphorylation of Kv1.1. Pflã¼Gers Archiv : European Journal of Physiology. 439: 18-26. PMID 10650996 DOI: 10.1007/S004249900139  0.496
1999 Shistik E, Keren-Raifman T, Idelson GH, Blumenstein Y, Dascal N, Ivanina T. The N terminus of the cardiac L-type Ca(2+) channel alpha(1C) subunit. The initial segment is ubiquitous and crucial for protein kinase C modulation, but is not directly phosphorylated. The Journal of Biological Chemistry. 274: 31145-9. PMID 10531304 DOI: 10.1074/Jbc.274.44.31145  0.417
1999 Blumenstein Y, Ivanina T, Shistik E, Bossi E, Peres A, Dascal N. Regulation of cardiac L-type Ca2+ channel by coexpression of G(alpha s) in Xenopus oocytes. Febs Letters. 444: 78-84. PMID 10037152 DOI: 10.1016/S0014-5793(99)00035-6  0.483
1998 Shistik E, Ivanina T, Blumenstein Y, Dascal N. Crucial role of N terminus in function of cardiac L-type Ca2+ channel and its modulation by protein kinase C. The Journal of Biological Chemistry. 273: 17901-9. PMID 9651396 DOI: 10.1074/Jbc.273.28.17901  0.536
1998 Vorobiov D, Levin G, Lotan I, Dascal N. Agonist-independent inactivation and agonist-induced desensitization of the G protein-activated K+ channel (GIRK) in Xenopus oocytes. Pflã¼Gers Archiv : European Journal of Physiology. 436: 56-68. PMID 9560447 DOI: 10.1007/S004240050604  0.477
1997 Dascal N. Signalling via the G protein-activated K+ channels. Cellular Signalling. 9: 551-73. PMID 9429760 DOI: 10.1016/S0898-6568(97)00095-8  0.59
1997 Luchian T, Dascal N, Dessauer C, Platzer D, Davidson N, Lester HA, Schreibmayer W. A C-terminal peptide of the GIRK1 subunit directly blocks the G protein-activated K+ channel (GIRK) expressed in Xenopus oocytes. The Journal of Physiology. 505: 13-22. PMID 9409468 DOI: 10.1111/J.1469-7793.1997.013Bc.X  0.68
1997 Gao T, Yatani A, Dell'Acqua ML, Sako H, Green SA, Dascal N, Scott JD, Hosey MM. cAMP-dependent regulation of cardiac L-type Ca2+ channels requires membrane targeting of PKA and phosphorylation of channel subunits. Neuron. 19: 185-96. PMID 9247274 DOI: 10.1016/S0896-6273(00)80358-X  0.533
1997 Sharon D, Vorobiov D, Dascal N. Positive and negative coupling of the metabotropic glutamate receptors to a G protein-activated K+ channel, GIRK, in Xenopus oocytes. The Journal of General Physiology. 109: 477-90. PMID 9101406 DOI: 10.1085/Jgp.109.4.477  0.71
1996 Perets T, Blumenstein Y, Shistik E, Lotan I, Dascal N. A potential site of functional modulation by protein kinase A in the cardiac Ca2+ channel alpha 1C subunit. Febs Letters. 384: 189-92. PMID 8612821 DOI: 10.1016/0014-5793(96)00303-1  0.517
1996 Schreibmayer W, Dessauer CW, Vorobiov D, Gilman AG, Lester HA, Davidson N, Dascal N. Inhibition of an inwardly rectifying K+ channel by G-protein alpha-subunits. Nature. 380: 624-7. PMID 8602262 DOI: 10.1038/380624A0  0.625
1996 DiMagno L, Dascal N, Davidson N, Lester HA, Schreibmayer W. Serotonin and protein kinase C modulation of a rat brain inwardly rectifying K+ channel expressed in xenopus oocytes. PflüGers Archiv : European Journal of Physiology. 431: 335-40. PMID 8584426 DOI: 10.1007/Bf02207270  0.603
1996 Schreibmayer W, Dessauer CW, Vorobiov D, Gilman AG, Lester HA, Davidson N, Dascal N. Correction: Inhibition of an inwardly rectifying K+ channel by G-protein α-subunits Nature. 383: 103-103. DOI: 10.1038/383103C0  0.585
1995 Shistik E, Ivanina T, Puri T, Hosey M, Dascal N. Ca2+ current enhancement by alpha 2/delta and beta subunits in Xenopus oocytes: contribution of changes in channel gating and alpha 1 protein level. The Journal of Physiology. 489: 55-62. PMID 8583415 DOI: 10.1113/Jphysiol.1995.Sp021029  0.356
1995 Lim NF, Dascal N, Labarca C, Davidson N, Lester HA. A G protein-gated K channel is activated via beta 2-adrenergic receptors and G beta gamma subunits in Xenopus oocytes. The Journal of General Physiology. 105: 421-39. PMID 7769382 DOI: 10.1085/Jgp.105.3.421  0.603
1995 Dascal N, Doupnik CA, Ivanina T, Bausch S, Wang W, Lin C, Garvey J, Chavkin C, Lester HA, Davidson N. Inhibition of function in Xenopus oocytes of the inwardly rectifying G-protein-activated atrial K channel (GIRK1) by overexpression of a membrane-attached form of the C-terminal tail. Proceedings of the National Academy of Sciences of the United States of America. 92: 6758-62. PMID 7542774 DOI: 10.1073/Pnas.92.15.6758  0.687
1994 Ivanina T, Perets T, Thornhill WB, Levin G, Dascal N, Lotan I. Phosphorylation by protein kinase A of RCK1 K+ channels expressed in Xenopus oocytes. Biochemistry. 33: 8786-92. PMID 8038169 DOI: 10.1021/Bi00195A021  0.495
1994 Karschin C, Schreibmayer W, Dascal N, Lester H, Davidson N, Karschin A. Distribution and localization of a G protein-coupled inwardly rectifying K+ channel in the rat. Febs Letters. 348: 139-44. PMID 8034029 DOI: 10.1016/0014-5793(94)00590-7  0.605
1994 Singer-Lahat D, Lotan I, Biel M, Flockerzi V, Hofmann F, Dascal N. Cardiac calcium channels expressed in Xenopus oocytes are modulated by dephosphorylation but not by cAMP-dependent phosphorylation. Receptors & Channels. 2: 215-26. PMID 7874448  0.413
1994 Schreibmayer W, Frohnwieser B, Dascal N, Platzer D, Spreitzer B, Zechner R, Kallen RG, Lester HA. Beta-adrenergic modulation of currents produced by rat cardiac Na+ channels expressed in Xenopus laevis oocytes. Receptors & Channels. 2: 339-50. PMID 7536612  0.57
1994 Schreibmayer W, Lester HA, Dascal N. Voltage clamping of Xenopus laevis oocytes utilizing agarose-cushion electrodes. Pflã¼Gers Archiv : European Journal of Physiology. 426: 453-8. PMID 7517034 DOI: 10.1007/Bf00388310  0.51
1993 Lester HA, Dascal N. Potassium channels. The response to vagusstoff. Nature. 364: 758-9. PMID 8355802 DOI: 10.1038/364758A0  0.474
1993 Dascal N, Lim NF, Schreibmayer W, Wang W, Davidson N, Lester HA. Expression of an atrial G-protein-activated potassium channel in Xenopus oocytes. Proceedings of the National Academy of Sciences of the United States of America. 90: 6596-600. PMID 8341673 DOI: 10.1073/Pnas.90.14.6596  0.679
1993 Dascal N, Schreibmayer W, Lim NF, Wang W, Chavkin C, DiMagno L, Labarca C, Kieffer BL, Gaveriaux-Ruff C, Trollinger D. Atrial G protein-activated K+ channel: expression cloning and molecular properties. Proceedings of the National Academy of Sciences of the United States of America. 90: 10235-9. PMID 8234283 DOI: 10.1073/Pnas.90.21.10235  0.604
1993 Biel M, Altenhofen W, Hullin R, Ludwig J, Freichel M, Flockerzi V, Dascal N, Kaupp UB, Hofmann F. Primary structure and functional expression of a cyclic nucleotide-gated channel from rabbit aorta. Febs Letters. 329: 134-8. PMID 7689061 DOI: 10.1016/0014-5793(93)80209-D  0.478
1992 Oron Y, Dascal N. Regulation of intracellular calcium activity in Xenopus oocytes. Methods in Enzymology. 207: 381-90. PMID 1528121 DOI: 10.1016/0076-6879(92)07027-L  0.423
1992 Gershon E, Weigl L, Lotan I, Schreibmayer W, Dascal N. Protein kinase A reduces voltage-dependent Na+ current in Xenopus oocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 3743-52. PMID 1383476 DOI: 10.1523/Jneurosci.12-10-03743.1992  0.514
1992 Singer-Lahat D, Lotan I, Itagaki K, Schwartz A, Dascal N. Evidence for the existence of RNA of Ca(2+)-channel alpha 2/delta subunit in Xenopus oocytes. Biochimica Et Biophysica Acta. 1137: 39-44. PMID 1382608 DOI: 10.1016/0167-4889(92)90097-U  0.381
1992 Dascal N, Chilcott G, Lester HA. Intracellular perfusion of Xenopus oocytes. Methods in Enzymology. 207: 345-52. PMID 1382190 DOI: 10.1016/0076-6879(92)07023-H  0.523
1992 Moran O, Schreibmayer W, Weigl L, Dascal N, Lotan I. Level of expression controls modes of gating of a K+ channel. Febs Letters. 302: 21-5. PMID 1375169 DOI: 10.1016/0014-5793(92)80275-L  0.463
1992 Asher C, Singer D, Eren R, Yeger O, Dascal N, Garty H. NaCl-dependent expression of amiloride-blockable Na+ channel in Xenopus oocytes. The American Journal of Physiology. 262: G244-8. PMID 1371644 DOI: 10.1152/Ajpgi.1992.262.2.G244  0.351
1992 Singer-Lahat D, Gershon E, Lotan I, Hullin R, Biel M, Flockerzi V, Hofmann F, Dascal N. Modulation of cardiac Ca2+ channels in Xenopus oocytes by protein kinase C. Febs Letters. 306: 113-8. PMID 1321730 DOI: 10.1016/0014-5793(92)80980-U  0.477
1992 Nargeot J, Dascal N, Lester HA. Heterologous expression of calcium channels. The Journal of Membrane Biology. 126: 97-108. PMID 1317459 DOI: 10.1007/Bf00231908  0.591
1992 Hullin R, Singer-Lahat D, Freichel M, Biel M, Dascal N, Hofmann F, Flockerzi V. Calcium channel beta subunit heterogeneity: functional expression of cloned cDNA from heart, aorta and brain. The Embo Journal. 11: 885-90. PMID 1312465 DOI: 10.1002/J.1460-2075.1992.Tb05126.X  0.422
1992 Dascal N, Lotan I, Karni E, Gigi A. Calcium channel currents in Xenopus oocytes injected with rat skeletal muscle RNA. The Journal of Physiology. 450: 469-90. PMID 1279162 DOI: 10.1113/Jphysiol.1992.Sp019137  0.46
1991 Moran O, Dascal N, Lotan I. Modulation of a Shaker potassium A-channel by protein kinase C activation. Febs Letters. 279: 256-60. PMID 1900473 DOI: 10.1016/0014-5793(91)80162-V  0.558
1991 Dascal N, Chilcott G, Lester HA. Recording of voltage and Ca(2+)-dependent currents in Xenopus oocytes using an intracellular perfusion method. Journal of Neuroscience Methods. 39: 29-38. PMID 1722267 DOI: 10.1016/0165-0270(91)90090-M  0.598
1991 Singer D, Biel M, Lotan I, Flockerzi V, Hofmann F, Dascal N. The roles of the subunits in the function of the calcium channel. Science (New York, N.Y.). 253: 1553-7. PMID 1716787 DOI: 10.1126/Science.1716787  0.453
1991 Dascal N, Lotan I. Activation of protein kinase C alters voltage dependence of a Na+ channel. Neuron. 6: 165-75. PMID 1702650 DOI: 10.1016/0896-6273(91)90131-I  0.504
1991 Schreibmayer W, Dascal N, Lotan I, Wallner M, Weigl L. Molecular mechanism of protein kinase C modulation of sodium channel alpha-subunits expressed in Xenopus oocytes. Febs Letters. 291: 341-4. PMID 1657647 DOI: 10.1016/0014-5793(91)81316-Z  0.508
1991 Biel M, Hullin R, Freundner S, Singer D, Dascal N, Flockerzi V, Hofmann F. Tissue-specific expression of high-voltage-activated dihydropyridine-sensitive L-type calcium channels. European Journal of Biochemistry / Febs. 200: 81-8. PMID 1652442 DOI: 10.1111/J.1432-1033.1991.Tb21051.X  0.359
1990 Dascal N. Analysis and functional characteristics of dihydropyridine-sensitive and -insensitive calcium channel proteins. Biochemical Pharmacology. 40: 1171-8. PMID 2169741 DOI: 10.1016/0006-2952(90)90380-4  0.46
1990 Lotan I, Dascal N, Naor Z, Boton R. Modulation of vertebrate brain Na+ and K+ channels by subtypes of protein kinase C. Febs Letters. 267: 25-8. PMID 1694792 DOI: 10.1016/0014-5793(90)80279-R  0.47
1990 Singer D, Boton R, Moran O, Dascal N. Short- and long-term desensitization of serotonergic response in Xenopus oocytes injected with brain RNA: roles for inositol 1,4,5-trisphosphate and protein kinase C. Pflã¼Gers Archiv : European Journal of Physiology. 416: 7-16. PMID 1693768 DOI: 10.1007/Bf00370215  0.326
1990 Boton R, Singer D, Dascal N. Inactivation of calcium-activated chloride conductance in Xenopus oocytes: roles of calcium and protein kinase C. Pflã¼Gers Archiv : European Journal of Physiology. 416: 1-6. PMID 1693766 DOI: 10.1007/Bf00370214  0.341
1989 Cohen-Armon M, Sokolovsky M, Dascal N. Modulation of the voltage-dependent sodium channel by agents affecting G-proteins: a study in Xenopus oocytes injected with brain RNA. Brain Research. 496: 197-203. PMID 2553201 DOI: 10.1016/0006-8993(89)91066-4  0.592
1989 Slish DF, Engle DB, Varadi G, Lotan I, Singer D, Dascal N, Schwartz A. Evidence for the existence of a cardiac specific isoform of the alpha 1 subunit of the voltage dependent calcium channel. Febs Letters. 250: 509-14. PMID 2546809 DOI: 10.1016/0014-5793(89)80786-0  0.337
1989 Boton R, Dascal N, Gillo B, Lass Y. Two calcium-activated chloride conductances in Xenopus laevis oocytes permeabilized with the ionophore A23187. The Journal of Physiology. 408: 511-34. PMID 2506341 DOI: 10.1113/Jphysiol.1989.Sp017473  0.324
1989 Lotan I, Gigi A, Dascal N. Expression of voltage-dependent Ca channels from skeletal muscle in Xenopus oocytes. Annals of the New York Academy of Sciences. 560: 183-4. PMID 2472765 DOI: 10.1111/J.1749-6632.1989.Tb24095.X  0.417
1989 Lester HA, Snutch TP, Leonard JP, Nargeot J, Dascal N, Curtis BM, Davidson N. Expression of mRNA encoding voltage-dependent Ca channels in Xenopus oocytes. Review and progress report. Annals of the New York Academy of Sciences. 560: 174-82. PMID 2472764 DOI: 10.1111/J.1749-6632.1989.Tb24094.X  0.701
1989 Moran O, Dascal N. Protein kinase C modulates neurotransmitter responses in Xenopus oocytes injected with rat brain RNA. Brain Research. Molecular Brain Research. 5: 193-202. PMID 2471032 DOI: 10.1016/0169-328X(89)90035-1  0.347
1989 Lotan I, Goelet P, Gigi A, Dascal N. Specific block of calcium channel expression by a fragment of dihydropyridine receptor cDNA. Science (New York, N.Y.). 243: 666-9. PMID 2464853 DOI: 10.1126/Science.2464853  0.466
1988 Gelerstein S, Shapira H, Dascal N, Yekuel R, Oron Y. Is a decrease in cyclic AMP a necessary and sufficient signal for maturation of amphibian oocytes? Developmental Biology. 127: 25-32. PMID 2834247 DOI: 10.1016/0012-1606(88)90185-6  0.316
1987 Lübbert H, Snutch TP, Dascal N, Lester HA, Davidson N. Rat brain 5-HT1C receptors are encoded by a 5-6 kbase mRNA size class and are functionally expressed in injected Xenopus oocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 1159-65. PMID 2883267 DOI: 10.1523/Jneurosci.07-04-01159.1987  0.624
1987 Dascal N. The use of Xenopus oocytes for the study of ion channels. Crc Critical Reviews in Biochemistry. 22: 317-87. PMID 2449311  0.417
1987 Dascal N, Lotan I, Lass Y. Dissociation of acetylcholine- and cyclic GMP-induced currents in Xenopus oocytes. Pflã¼Gers Archiv : European Journal of Physiology. 409: 521-7. PMID 2442713 DOI: 10.1007/Bf00583810  0.38
1987 Dascal N, Cohen S. Further characterization of the slow muscarinic responses in Xenopus oocytes. Pflã¼Gers Archiv : European Journal of Physiology. 409: 512-20. PMID 2442712 DOI: 10.1007/Bf00583809  0.319
1986 Lotan H, Dascal N, Cohen S, Lass Y. ATP-evoked membrane responses in Xenopus oocytes. Pflã¼Gers Archiv : European Journal of Physiology. 406: 158-62. PMID 3960699 DOI: 10.1007/Bf00586677  0.374
1986 Dascal N, Ifune C, Hopkins R, Snutch TP, Lübbert H, Davidson N, Simon MI, Lester HA. Involvement of a GTP-binding protein in mediation of serotonin and acetylcholine responses in Xenopus oocytes injected with rat brain messenger RNA. Brain Research. 387: 201-9. PMID 2435359 DOI: 10.1016/0169-328X(86)90026-4  0.632
1986 Dascal N, Snutch TP, Lübbert H, Davidson N, Lester HA. Expression and modulation of voltage-gated calcium channels after RNA injection in Xenopus oocytes. Science (New York, N.Y.). 231: 1147-50. PMID 2418503 DOI: 10.1126/Science.2418503  0.685
1985 Dascal N, Lotan I, Gillo B, Lester HA, Lass Y. Acetylcholine and phorbol esters inhibit potassium currents evoked by adenosine and cAMP in Xenopus oocytes. Proceedings of the National Academy of Sciences of the United States of America. 82: 6001-5. PMID 2994058 DOI: 10.1073/Pnas.82.17.6001  0.55
1985 Dascal N, Gillo B, Lass Y. Role of calcium mobilization in mediation of acetylcholine-evoked chloride currents in Xenopus laevis oocytes. The Journal of Physiology. 366: 299-313. PMID 2414433 DOI: 10.1113/Jphysiol.1985.Sp015799  0.304
1984 Dascal N, Landau EM, Lass Y. Xenopus oocyte resting potential, muscarinic responses and the role of calcium and guanosine 3',5'-cyclic monophosphate. The Journal of Physiology. 352: 551-74. PMID 6086916 DOI: 10.1113/Jphysiol.1984.Sp015310  0.328
1982 Lotan I, Dascal N, Cohen S, Lass Y. Adenosine-induced slow ionic currents in the Xenopus oocyte. Nature. 298: 572-4. PMID 6285198 DOI: 10.1038/298572A0  0.343
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