Henry A. Lester, PhD - Publications

Affiliations: 
Neuroscience California Institute of Technology, Pasadena, CA 
Area:
Molecular and functional aspects of ion channels, receptors, and transporters

329 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Shivange AV, Borden PM, Muthusamy AK, Nichols AL, Bera K, Bao H, Bishara I, Jeon J, Mulcahy MJ, Cohen B, O'Riordan SL, Kim C, Dougherty DA, Chapman ER, Marvin J, ... ... Lester HA, et al. Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors. The Journal of General Physiology. PMID 30718376 DOI: 10.1085/jgp.201812201  1
2019 Bavan S, Kim CH, Henderson BJ, Lester HA. Chronic menthol does not change stoichiometry or functional plasma membrane levels of mouse α3β4-containing nicotinic acetylcholine receptors. Molecular Pharmacology. PMID 30670481 DOI: 10.1124/mol.118.114769  1
2019 Zhou C, Gu W, Wu H, Yan X, Deshpande P, Xiao C, Lester HA. Bidirectional dopamine modulation of excitatory and inhibitory synaptic inputs to subthalamic neuron subsets containing α4β2 or α7 nAChRs. Neuropharmacology. PMID 30660626 DOI: 10.1016/j.neuropharm.2019.01.015  1
2018 Henderson BJ, Grant S, Chu BW, Shahoei R, Huard SM, Saladi SSM, Tajkhorshid E, Dougherty DA, Lester HA. Menthol Stereoisomers Exhibit Different Effects on α4β2 nAChR Upregulation and Dopamine Neuron Spontaneous Firing. Eneuro. 5. PMID 30627659 DOI: 10.1523/ENEURO.0465-18.2018  1
2018 Banala S, Arvin MC, Bannon NM, Jin XT, Macklin JJ, Wang Y, Peng C, Zhao G, Marshall JJ, Gee KR, Wokosin DL, Kim VJ, McIntosh JM, Contractor A, Lester HA, et al. Photoactivatable drugs for nicotinic optopharmacology. Nature Methods. PMID 29578537 DOI: 10.1038/nmeth.4637  1
2017 Parker RL, O'Neill HC, Henley BM, Wageman CR, Drenan RM, Marks MJ, Miwa JM, Grady SR, Lester HA. Deletion of lynx1 reduces the function of α6* nicotinic receptors. Plos One. 12: e0188715. PMID 29206881 DOI: 10.1371/journal.pone.0188715  1
2017 Wall TR, Henderson BJ, Voren G, Wageman CR, Deshpande P, Cohen BN, Grady SR, Marks MJ, Yohannes D, Kenny PJ, Bencherif M, Lester HA. TC299423, a Novel Agonist for Nicotinic Acetylcholine Receptors. Frontiers in Pharmacology. 8: 641. PMID 29033834 DOI: 10.3389/fphar.2017.00641  1
2017 Hurtado-Zavala JI, Ramachandran B, Ahmed S, Halder R, Bolleyer C, Awasthi A, Stahlberg MA, Wagener RJ, Anderson K, Drenan RM, Lester HA, Miwa JM, Staiger JF, Fischer A, Dean C. TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus. Nature Communications. 8: 15878. PMID 28722015 DOI: 10.1038/ncomms15878  1
2017 Post MR, Tender GS, Lester HA, Dougherty DA. Secondary Ammonium Agonists Make Dual Cation-π Interactions in α4β2 Nicotinic Receptors. Eneuro. 4. PMID 28589175 DOI: 10.1523/ENEURO.0032-17.2017  1
2017 Henderson BJ, Wall TR, Henley BM, Kim CH, McKinney S, Lester HA. Menthol Enhances Nicotine Reward-Related Behavior by Potentiating Nicotine-Induced Changes in nAChR Function, nAChR Upregulation, and DA Neuron Excitability. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28401925 DOI: 10.1038/npp.2017.72  1
2017 Henley BM, Cohen BN, Kim CH, Gold HD, Srinivasan R, McKinney S, Deshpande P, Lester HA. Reliable Identification of Living Dopaminergic Neurons in Midbrain Cultures Using RNA Sequencing and TH-promoter-driven eGFP Expression. Journal of Visualized Experiments : Jove. PMID 28287593 DOI: 10.3791/54981  1
2017 Post M, Lester HA, Dougherty DA. Probing for and Quantifying Agonist Hydrogen Bonds in α6β2 Nicotinic Acetylcholine Receptors. Biochemistry. PMID 28287260 DOI: 10.1021/acs.biochem.7b00213  1
2016 Kim J, Henley BM, Kim CH, Lester HA, Yang C. Incubator embedded cell culture imaging system (EmSight) based on Fourier ptychographic microscopy. Biomedical Optics Express. 7: 3097-110. PMID 27570701 DOI: 10.1364/BOE.7.003097  1
2016 Nichols WA, Henderson BJ, Marotta CB, Yu CY, Richards C, Dougherty DA, Lester HA, Cohen BN. Mutation Linked to Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Reduces Low-Sensitivity α4β2, and Increases α5α4β2, Nicotinic Receptor Surface Expression. Plos One. 11: e0158032. PMID 27336596 DOI: 10.1371/journal.pone.0158032  1
2016 Henderson BJ, Wall TR, Henley BM, Kim CH, Nichols WA, Moaddel R, Xiao C, Lester HA. Menthol Alone Upregulates Midbrain nAChRs, Alters nAChR Subtype Stoichiometry, Alters Dopamine Neuron Firing Frequency, and Prevents Nicotine Reward. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 2957-74. PMID 26961950 DOI: 10.1523/JNEUROSCI.4194-15.2016  1
2016 Srinivasan R, Henley BM, Henderson BJ, Indersmitten T, Cohen BN, Kim CH, McKinney S, Deshpande P, Xiao C, Lester HA. Smoking-Relevant Nicotine Concentration Attenuates the Unfolded Protein Response in Dopaminergic Neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 65-79. PMID 26740650 DOI: 10.1523/JNEUROSCI.2126-15.2016  1
2015 Marotta CB, Lester HA, Dougherty DA. An Unaltered Orthosteric Site and a Network of Long-Range Allosteric Interactions for PNU-120596 in α7 Nicotinic Acetylcholine Receptors. Chemistry & Biology. 22: 1063-73. PMID 26211363 DOI: 10.1016/j.chembiol.2015.06.018  1
2015 Lester HA, Lavis LD, Dougherty DA. Ketamine Inside Neurons? The American Journal of Psychiatry. appiajp201514121537. PMID 26183700 DOI: 10.1176/appi.ajp.2015.14121537  1
2015 Wieskopf JS, Mathur J, Limapichat W, Post MR, Al-Qazzaz M, Sorge RE, Martin LJ, Zaykin DV, Smith SB, Freitas K, Austin JS, Dai F, Zhang J, Marcovitz J, Tuttle AH, ... ... Lester HA, et al. The nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors. Science Translational Medicine. 7: 287ra72. PMID 25972004 DOI: 10.1126/scitranslmed.3009986  1
2015 Post MR, Limapichat W, Lester HA, Dougherty DA. Heterologous expression and nonsense suppression provide insights into agonist behavior at α6β2 nicotinic acetylcholine receptors. Neuropharmacology. 97: 376-382. PMID 25908401 DOI: 10.1016/j.neuropharm.2015.04.009  1
2015 Xiao C, Miwa JM, Henderson BJ, Wang Y, Deshpande P, McKinney SL, Lester HA. Nicotinic receptor subtype-selective circuit patterns in the subthalamic nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 3734-46. PMID 25740504 DOI: 10.1523/JNEUROSCI.3528-14.2015  1
2015 Sinkus ML, Graw S, Freedman R, Ross RG, Lester HA, Leonard S. The human CHRNA7 and CHRFAM7A genes: A review of the genetics, regulation, and function. Neuropharmacology. 96: 274-88. PMID 25701707 DOI: 10.1016/j.neuropharm.2015.02.006  1
2015 Henderson BJ, Lester HA. Inside-out neuropharmacology of nicotinic drugs. Neuropharmacology. 96: 178-93. PMID 25660637 DOI: 10.1016/j.neuropharm.2015.01.022  1
2015 Miles TF, Lester HA, Dougherty DA. Allosteric activation of the 5-HT3AB receptor by mCPBG. Neuropharmacology. 91: 103-8. PMID 25541413 DOI: 10.1016/j.neuropharm.2014.12.018  1
2014 Nichols WA, Henderson BJ, Yu C, Parker RL, Richards CI, Lester HA, Miwa JM. Lynx1 shifts α4β2 nicotinic receptor subunit stoichiometry by affecting assembly in the endoplasmic reticulum. The Journal of Biological Chemistry. 289: 31423-32. PMID 25193667 DOI: 10.1074/jbc.M114.573667  1
2014 Wang Y, Xiao C, Indersmitten T, Freedman R, Leonard S, Lester HA. The duplicated α7 subunits assemble and form functional nicotinic receptors with the full-length α7. The Journal of Biological Chemistry. 289: 26451-63. PMID 25056953 DOI: 10.1074/jbc.M114.582858  1
2014 Daeffler KN, Lester HA, Dougherty DA. Functional evaluation of key interactions evident in the structure of the eukaryotic Cys-loop receptor GluCl. Acs Chemical Biology. 9: 2283-90. PMID 25051140 DOI: 10.1021/cb500323d  1
2014 Shih PY, Engle SE, Oh G, Deshpande P, Puskar NL, Lester HA, Drenan RM. Differential expression and function of nicotinic acetylcholine receptors in subdivisions of medial habenula. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 9789-802. PMID 25031416 DOI: 10.1523/JNEUROSCI.0476-14.2014  1
2014 Kobayashi A, Parker RL, Wright AP, Brahem H, Ku P, Oliver KM, Walz A, Lester HA, Miwa JM. Lynx1 supports neuronal health in the mouse dorsal striatum during aging: an ultrastructural investigation. Journal of Molecular Neuroscience : Mn. 53: 525-36. PMID 25027556 DOI: 10.1007/s12031-014-0352-1  1
2014 Limapichat W, Dougherty DA, Lester HA. Subtype-specific mechanisms for functional interaction between α6β4* nicotinic acetylcholine receptors and P2X receptors. Molecular Pharmacology. 86: 263-74. PMID 24966348 DOI: 10.1124/mol.114.093179  1
2014 Srinivasan R, Henderson BJ, Lester HA, Richards CI. Pharmacological chaperoning of nAChRs: a therapeutic target for Parkinson's disease. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 83: 20-9. PMID 24593907 DOI: 10.1016/j.phrs.2014.02.005  1
2014 Marotta CB, Rreza I, Lester HA, Dougherty DA. Selective ligand behaviors provide new insights into agonist activation of nicotinic acetylcholine receptors. Acs Chemical Biology. 9: 1153-9. PMID 24564429 DOI: 10.1021/cb400937d  1
2014 Henderson BJ, Srinivasan R, Nichols WA, Dilworth CN, Gutierrez DF, Mackey ED, McKinney S, Drenan RM, Richards CI, Lester HA. Nicotine exploits a COPI-mediated process for chaperone-mediated up-regulation of its receptors. The Journal of General Physiology. 143: 51-66. PMID 24378908 DOI: 10.1085/jgp.201311102  1
2014 Marotta CB, Dilworth CN, Lester HA, Dougherty DA. Probing the non-canonical interface for agonist interaction with an α5 containing nicotinic acetylcholine receptor. Neuropharmacology. 77: 342-9. PMID 24144909 DOI: 10.1016/j.neuropharm.2013.09.028  1
2013 Miles TF, Dougherty DA, Lester HA. The 5-HT3AB receptor shows an A3B2 stoichiometry at the plasma membrane. Biophysical Journal. 105: 887-98. PMID 23972841 DOI: 10.1016/j.bpj.2013.07.015  1
2013 Henley BM, Williams BA, Srinivasan R, Cohen BN, Xiao C, Mackey ED, Wold BJ, Lester HA. Transcriptional regulation by nicotine in dopaminergic neurons. Biochemical Pharmacology. 86: 1074-83. PMID 23939186 DOI: 10.1016/j.bcp.2013.07.031  1
2013 Chatterjee S, Santos N, Holgate J, Haass-Koffler CL, Hopf FW, Kharazia V, Lester H, Bonci A, Bartlett SE. The α5 subunit regulates the expression and function of α4*-containing neuronal nicotinic acetylcholine receptors in the ventral-tegmental area. Plos One. 8: e68300. PMID 23869214 DOI: 10.1371/journal.pone.0068300  1
2013 Frazier SJ, Cohen BN, Lester HA. An engineered glutamate-gated chloride (GluCl) channel for sensitive, consistent neuronal silencing by ivermectin. The Journal of Biological Chemistry. 288: 21029-42. PMID 23720773 DOI: 10.1074/jbc.M112.423921  1
2013 Van Arnam EB, Blythe EE, Lester HA, Dougherty DA. An unusual pattern of ligand-receptor interactions for the α7 nicotinic acetylcholine receptor, with implications for the binding of varenicline. Molecular Pharmacology. 84: 201-7. PMID 23680636 DOI: 10.1124/mol.113.085795  1
2013 Limapichat W, Yu WY, Branigan E, Lester HA, Dougherty DA. Key binding interactions for memantine in the NMDA receptor. Acs Chemical Neuroscience. 4: 255-60. PMID 23421676 DOI: 10.1021/cn300180a  1
2013 Blum AP, Van Arnam EB, German LA, Lester HA, Dougherty DA. Binding interactions with the complementary subunit of nicotinic receptors. The Journal of Biological Chemistry. 288: 6991-7. PMID 23349463 DOI: 10.1074/jbc.M112.439968  1
2013 O'Neill HC, Laverty DC, Patzlaff NE, Cohen BN, Fonck C, McKinney S, McIntosh JM, Lindstrom JM, Lester HA, Grady SR, Marks MJ. Mice expressing the ADNFLE valine 287 leucine mutation of the Β2 nicotinic acetylcholine receptor subunit display increased sensitivity to acute nicotine administration and altered presynaptic nicotinic receptor function. Pharmacology, Biochemistry, and Behavior. 103: 603-21. PMID 23123803 DOI: 10.1016/j.pbb.2012.10.014  1
2012 Miles TF, Bower KS, Lester HA, Dougherty DA. A coupled array of noncovalent interactions impacts the function of the 5-HT3A serotonin receptor in an agonist-specific way. Acs Chemical Neuroscience. 3: 753-60. PMID 23077719 DOI: 10.1021/cn3000586  1
2012 Scott KM, Du J, Lester HA, Masmanidis SC. Variability of acute extracellular action potential measurements with multisite silicon probes. Journal of Neuroscience Methods. 211: 22-30. PMID 22971352 DOI: 10.1016/j.jneumeth.2012.08.005  1
2012 Srinivasan R, Richards CI, Dilworth C, Moss FJ, Dougherty DA, Lester HA. Förster Resonance Energy Transfer (FRET) Correlates of Altered Subunit Stoichiometry in Cys-Loop Receptors, Exemplified by Nicotinic α4β2. International Journal of Molecular Sciences. 13: 10022-40. PMID 22949846 DOI: 10.3390/ijms130810022  1
2012 Daeffler KN, Lester HA, Dougherty DA. Functionally important aromatic-aromatic and sulfur-π interactions in the D2 dopamine receptor. Journal of the American Chemical Society. 134: 14890-6. PMID 22897614 DOI: 10.1021/ja304560x  1
2012 Shapiro MG, Frazier SJ, Lester HA. Unparalleled control of neural activity using orthogonal pharmacogenetics. Acs Chemical Neuroscience. 3: 619-29. PMID 22896806 DOI: 10.1021/cn300053q  1
2012 Drenan RM, Lester HA. Insights into the neurobiology of the nicotinic cholinergic system and nicotine addiction from mice expressing nicotinic receptors harboring gain-of-function mutations. Pharmacological Reviews. 64: 869-79. PMID 22885704 DOI: 10.1124/pr.111.004671  1
2012 Miwa JM, Lester HA, Walz A. Optimizing cholinergic tone through lynx modulators of nicotinic receptors: implications for plasticity and nicotine addiction. Physiology (Bethesda, Md.). 27: 187-99. PMID 22875450 DOI: 10.1152/physiol.00002.2012  1
2012 Duffy NH, Lester HA, Dougherty DA. Ondansetron and granisetron binding orientation in the 5-HT(3) receptor determined by unnatural amino acid mutagenesis. Acs Chemical Biology. 7: 1738-45. PMID 22873819 DOI: 10.1021/cb300246j  1
2012 Mackey ED, Engle SE, Kim MR, O'Neill HC, Wageman CR, Patzlaff NE, Wang Y, Grady SR, McIntosh JM, Marks MJ, Lester HA, Drenan RM. α6* nicotinic acetylcholine receptor expression and function in a visual salience circuit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10226-37. PMID 22836257 DOI: 10.1523/JNEUROSCI.0007-12.2012  1
2012 Lester HA, Miwa JM, Srinivasan R. Psychiatric drugs bind to classical targets within early exocytotic pathways: therapeutic effects. Biological Psychiatry. 72: 907-15. PMID 22771239 DOI: 10.1016/j.biopsych.2012.05.020  1
2012 Tavares Xda S, Blum AP, Nakamura DT, Puskar NL, Shanata JA, Lester HA, Dougherty DA. Variations in binding among several agonists at two stoichiometries of the neuronal, α4β2 nicotinic receptor. Journal of the American Chemical Society. 134: 11474-80. PMID 22716019 DOI: 10.1021/ja3011379  1
2012 Richards CI, Luong K, Srinivasan R, Turner SW, Dougherty DA, Korlach J, Lester HA. Live-cell imaging of single receptor composition using zero-mode waveguide nanostructures. Nano Letters. 12: 3690-4. PMID 22668081 DOI: 10.1021/nl301480h  1
2012 Liu CY, Xiao C, Fraser SE, Lester HA, Koos DS. Electrophysiological characterization of Grueneberg ganglion olfactory neurons: spontaneous firing, sodium conductance, and hyperpolarization-activated currents. Journal of Neurophysiology. 108: 1318-34. PMID 22649209 DOI: 10.1152/jn.00907.2011  1
2012 Srinivasan R, Richards CI, Xiao C, Rhee D, Pantoja R, Dougherty DA, Miwa JM, Lester HA. Pharmacological chaperoning of nicotinic acetylcholine receptors reduces the endoplasmic reticulum stress response. Molecular Pharmacology. 81: 759-69. PMID 22379121 DOI: 10.1124/mol.112.077792  1
2012 Puskar NL, Lester HA, Dougherty DA. Probing the effects of residues located outside the agonist binding site on drug-receptor selectivity in the nicotinic receptor. Acs Chemical Biology. 7: 841-6. PMID 22296725 DOI: 10.1021/cb200448j  1
2012 Cohen BN, Mackey ED, Grady SR, McKinney S, Patzlaff NE, Wageman CR, McIntosh JM, Marks MJ, Lester HA, Drenan RM. Nicotinic cholinergic mechanisms causing elevated dopamine release and abnormal locomotor behavior. Neuroscience. 200: 31-41. PMID 22079576 DOI: 10.1016/j.neuroscience.2011.10.047  1
2012 Shanata JA, Frazier SJ, Lester HA, Dougherty DA. Using mutant cycle analysis to elucidate long-range functional coupling in allosteric receptors. Methods in Molecular Biology (Clifton, N.J.). 796: 97-113. PMID 22052487 DOI: 10.1007/978-1-61779-334-9_6  1
2012 Murray TA, Bertrand D, Papke RL, George AA, Pantoja R, Srinivasan R, Liu Q, Wu J, Whiteaker P, Lester HA, Lukas RJ. α7β2 nicotinic acetylcholine receptors assemble, function, and are activated primarily via their α7-α7 interfaces. Molecular Pharmacology. 81: 175-88. PMID 22039094 DOI: 10.1124/mol.111.074088  1
2011 Du J, Blanche TJ, Harrison RR, Lester HA, Masmanidis SC. Multiplexed, high density electrophysiology with nanofabricated neural probes. Plos One. 6: e26204. PMID 22022568 DOI: 10.1371/journal.pone.0026204  1
2011 Van Arnam EB, Lester HA, Dougherty DA. Dissecting the functions of conserved prolines within transmembrane helices of the D2 dopamine receptor. Acs Chemical Biology. 6: 1063-8. PMID 21776983 DOI: 10.1021/cb200153g  1
2011 Lummis SC, Thompson AJ, Bencherif M, Lester HA. Varenicline is a potent agonist of the human 5-hydroxytryptamine3 receptor. The Journal of Pharmacology and Experimental Therapeutics. 339: 125-31. PMID 21775477 DOI: 10.1124/jpet.111.185306  1
2011 Richards CI, Srinivasan R, Xiao C, Mackey ED, Miwa JM, Lester HA. Trafficking of alpha4* nicotinic receptors revealed by superecliptic phluorin: effects of a beta4 amyotrophic lateral sclerosis-associated mutation and chronic exposure to nicotine. The Journal of Biological Chemistry. 286: 31241-9. PMID 21768117 DOI: 10.1074/jbc.M111.256024  1
2011 Blum AP, Gleitsman KR, Lester HA, Dougherty DA. Evidence for an extended hydrogen bond network in the binding site of the nicotinic receptor: role of the vicinal disulfide of the alpha1 subunit. The Journal of Biological Chemistry. 286: 32251-8. PMID 21757705 DOI: 10.1074/jbc.M111.254235  1
2011 Xiao C, Srinivasan R, Drenan RM, Mackey ED, McIntosh JM, Lester HA. Characterizing functional α6β2 nicotinic acetylcholine receptors in vitro: mutant β2 subunits improve membrane expression, and fluorescent proteins reveal responsive cells. Biochemical Pharmacology. 82: 852-61. PMID 21609715 DOI: 10.1016/j.bcp.2011.05.005  1
2011 Miwa JM, Freedman R, Lester HA. Neural systems governed by nicotinic acetylcholine receptors: emerging hypotheses. Neuron. 70: 20-33. PMID 21482353 DOI: 10.1016/j.neuron.2011.03.014  1
2011 Puskar NL, Xiu X, Lester HA, Dougherty DA. Two neuronal nicotinic acetylcholine receptors, alpha4beta4 and alpha7, show differential agonist binding modes. The Journal of Biological Chemistry. 286: 14618-27. PMID 21343288 DOI: 10.1074/jbc.M110.206565  1
2011 Pless SA, Hanek AP, Price KL, Lynch JW, Lester HA, Dougherty DA, Lummis SC. A cation-π interaction at a phenylalanine residue in the glycine receptor binding site is conserved for different agonists. Molecular Pharmacology. 79: 742-8. PMID 21266487 DOI: 10.1124/mol.110.069583  1
2011 Srinivasan R, Pantoja R, Moss FJ, Mackey ED, Son CD, Miwa J, Lester HA. Nicotine up-regulates alpha4beta2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning. The Journal of General Physiology. 137: 59-79. PMID 21187334 DOI: 10.1085/jgp.201010532  1
2011 Xu J, Cohen BN, Zhu Y, Dziewczapolski G, Panda S, Lester HA, Heinemann SF, Contractor A. Altered activity-rest patterns in mice with a human autosomal-dominant nocturnal frontal lobe epilepsy mutation in the β2 nicotinic receptor. Molecular Psychiatry. 16: 1048-61. PMID 20603624 DOI: 10.1038/mp.2010.78  1
2011 Puskar NL, Xiu X, Lester HA, Dougherty DA. Two neuronal nicotinic acetylcholine receptors, α4β4 and α7, show differential agonist binding modes (Journal of Biological Chemistry (2011) 286, (14618-14627)) Journal of Biological Chemistry. 286: 29442. DOI: 10.1074/jbc.A110.206565  1
2010 Thompson AJ, Lester HA, Lummis SC. The structural basis of function in Cys-loop receptors. Quarterly Reviews of Biophysics. 43: 449-99. PMID 20849671 DOI: 10.1017/S0033583510000168  1
2010 Drenan RM, Grady SR, Steele AD, McKinney S, Patzlaff NE, McIntosh JM, Marks MJ, Miwa JM, Lester HA. Cholinergic modulation of locomotion and striatal dopamine release is mediated by alpha6alpha4* nicotinic acetylcholine receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9877-89. PMID 20660270 DOI: 10.1523/JNEUROSCI.2056-10.2010  1
2010 Blum AP, Lester HA, Dougherty DA. Nicotinic pharmacophore: the pyridine N of nicotine and carbonyl of acetylcholine hydrogen bond across a subunit interface to a backbone NH. Proceedings of the National Academy of Sciences of the United States of America. 107: 13206-11. PMID 20616056 DOI: 10.1073/pnas.1007140107  1
2010 Hanek AP, Lester HA, Dougherty DA. Photochemical proteolysis of an unstructured linker of the GABAAR extracellular domain prevents GABA but not pentobarbital activation. Molecular Pharmacology. 78: 29-35. PMID 20363860 DOI: 10.1124/mol.109.059832  1
2010 Grady SR, Drenan RM, Breining SR, Yohannes D, Wageman CR, Fedorov NB, McKinney S, Whiteaker P, Bencherif M, Lester HA, Marks MJ. Structural differences determine the relative selectivity of nicotinic compounds for native alpha 4 beta 2*-, alpha 6 beta 2*-, alpha 3 beta 4*- and alpha 7-nicotine acetylcholine receptors. Neuropharmacology. 58: 1054-66. PMID 20114055 DOI: 10.1016/j.neuropharm.2010.01.013  1
2010 Limapichat W, Lester HA, Dougherty DA. Chemical scale studies of the Phe-Pro conserved motif in the cys loop of Cys loop receptors. The Journal of Biological Chemistry. 285: 8976-84. PMID 20068044 DOI: 10.1074/jbc.M109.060939  1
2010 Zhao-Shea R, Cohen BN, Just H, McClure-Begley T, Whiteaker P, Grady SR, Salminen O, Gardner PD, Lester HA, Tapper AR. Dopamine D2-receptor activation elicits akinesia, rigidity, catalepsy, and tremor in mice expressing hypersensitive {alpha}4 nicotinic receptors via a cholinergic-dependent mechanism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 49-57. PMID 19720621 DOI: 10.1096/fj.09-137034  1
2009 Moss FJ, Imoukhuede PI, Scott K, Hu J, Jankowsky JL, Quick MW, Lester HA. GABA transporter function, oligomerization state, and anchoring: correlates with subcellularly resolved FRET. The Journal of General Physiology. 134: 489-521. PMID 19948998 DOI: 10.1085/jgp.200910314  1
2009 Xiao C, Nashmi R, McKinney S, Cai H, McIntosh JM, Lester HA. Chronic nicotine selectively enhances alpha4beta2* nicotinic acetylcholine receptors in the nigrostriatal dopamine pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12428-39. PMID 19812319 DOI: 10.1523/JNEUROSCI.2939-09.2009  1
2009 Torrice MM, Bower KS, Lester HA, Dougherty DA. Probing the role of the cation-pi interaction in the binding sites of GPCRs using unnatural amino acids. Proceedings of the National Academy of Sciences of the United States of America. 106: 11919-24. PMID 19581583 DOI: 10.1073/pnas.0903260106  1
2009 Breining SR, Bencherif M, Grady SR, Whiteaker P, Marks MJ, Wageman CR, Lester HA, Yohannes D. Evaluation of structurally diverse neuronal nicotinic receptor ligands for selectivity at the alpha6( *) subtype. Bioorganic & Medicinal Chemistry Letters. 19: 4359-63. PMID 19560354 DOI: 10.1016/j.bmcl.2009.05.085  1
2009 Gleitsman KR, Lester HA, Dougherty DA. Probing the role of backbone hydrogen bonding in a critical beta sheet of the extracellular domain of a cys-loop receptor. Chembiochem : a European Journal of Chemical Biology. 10: 1385-91. PMID 19405066 DOI: 10.1002/cbic.200900092  1
2009 Gleitsman KR, Shanata JA, Frazier SJ, Lester HA, Dougherty DA. Long-range coupling in an allosteric receptor revealed by mutant cycle analysis. Biophysical Journal. 96: 3168-78. PMID 19383461 DOI: 10.1016/j.bpj.2008.12.3949  1
2009 Imoukhuede PI, Moss FJ, Michael DJ, Chow RH, Lester HA. Ezrin mediates tethering of the gamma-aminobutyric acid transporter GAT1 to actin filaments via a C-terminal PDZ-interacting domain. Biophysical Journal. 96: 2949-60. PMID 19348776 DOI: 10.1016/j.bpj.2008.11.070  1
2009 Bohland JW, Wu C, Barbas H, Bokil H, Bota M, Breiter HC, Cline HT, Doyle JC, Freed PJ, Greenspan RJ, Haber SN, Hawrylycz M, Herrera DG, Hilgetag CC, Huang ZJ, ... ... Lester HA, et al. A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale. Plos Computational Biology. 5: e1000334. PMID 19325892 DOI: 10.1371/journal.pcbi.1000334  1
2009 Lester HA, Xiao C, Srinivasan R, Son CD, Miwa J, Pantoja R, Banghart MR, Dougherty DA, Goate AM, Wang JC. Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery. The Aaps Journal. 11: 167-77. PMID 19280351 DOI: 10.1208/s12248-009-9090-7  1
2009 Xiu X, Puskar NL, Shanata JA, Lester HA, Dougherty DA. Nicotine binding to brain receptors requires a strong cation-pi interaction. Nature. 458: 534-7. PMID 19252481 DOI: 10.1038/nature07768  1
2009 Son CD, Moss FJ, Cohen BN, Lester HA. Nicotine normalizes intracellular subunit stoichiometry of nicotinic receptors carrying mutations linked to autosomal dominant nocturnal frontal lobe epilepsy. Molecular Pharmacology. 75: 1137-48. PMID 19237585 DOI: 10.1124/mol.108.054494  1
2009 Pantoja R, Rodriguez EA, Dibas MI, Dougherty DA, Lester HA. Single-molecule imaging of a fluorescent unnatural amino acid incorporated into nicotinic receptors. Biophysical Journal. 96: 226-37. PMID 19134478 DOI: 10.1016/j.bpj.2008.09.034  1
2009 Fonck C, Nashmi R, Salas R, Zhou C, Huang Q, De Biasi M, Lester RA, Lester HA. Demonstration of functional alpha4-containing nicotinic receptors in the medial habenula. Neuropharmacology. 56: 247-53. PMID 18789953 DOI: 10.1016/j.neuropharm.2008.08.021  1
2008 Gleitsman KR, Kedrowski SM, Lester HA, Dougherty DA. An intersubunit hydrogen bond in the nicotinic acetylcholine receptor that contributes to channel gating. The Journal of Biological Chemistry. 283: 35638-43. PMID 18952603 DOI: 10.1074/jbc.M807226200  1
2008 Pless SA, Millen KS, Hanek AP, Lynch JW, Lester HA, Lummis SC, Dougherty DA. A cation-pi interaction in the binding site of the glycine receptor is mediated by a phenylalanine residue. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10937-42. PMID 18945901 DOI: 10.1523/JNEUROSCI.2540-08.2008  1
2008 Drenan RM, Grady SR, Whiteaker P, McClure-Begley T, McKinney S, Miwa JM, Bupp S, Heintz N, McIntosh JM, Bencherif M, Marks MJ, Lester HA. In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors. Neuron. 60: 123-36. PMID 18940593 DOI: 10.1016/j.neuron.2008.09.009  1
2008 Hanek AP, Lester HA, Dougherty DA. A stereochemical test of a proposed structural feature of the nicotinic acetylcholine receptor. Journal of the American Chemical Society. 130: 13216-8. PMID 18781739 DOI: 10.1021/ja8015457  1
2008 Price KL, Bower KS, Thompson AJ, Lester HA, Dougherty DA, Lummis SC. A hydrogen bond in loop A is critical for the binding and function of the 5-HT3 receptor. Biochemistry. 47: 6370-7. PMID 18498149 DOI: 10.1021/bi800222n  1
2008 Maurer JA, Elmore DE, Clayton D, Xiong L, Lester HA, Dougherty DA. Confirming the revised C-terminal domain of the MscL crystal structure. Biophysical Journal. 94: 4662-7. PMID 18326638 DOI: 10.1529/biophysj.107.127365  1
2008 Shao XM, Tan W, Xiu J, Puskar N, Fonck C, Lester HA, Feldman JL. Alpha4* nicotinic receptors in preBotzinger complex mediate cholinergic/nicotinic modulation of respiratory rhythm. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 519-28. PMID 18184794 DOI: 10.1523/JNEUROSCI.3666-07.2008  1
2008 Drenan RM, Nashmi R, Imoukhuede P, Just H, McKinney S, Lester HA. Subcellular trafficking, pentameric assembly, and subunit stoichiometry of neuronal nicotinic acetylcholine receptors containing fluorescently labeled alpha6 and beta3 subunits. Molecular Pharmacology. 73: 27-41. PMID 17932221 DOI: 10.1124/mol.107.039180  1
2007 Pless SA, Dibas MI, Lester HA, Lynch JW. Conformational variability of the glycine receptor M2 domain in response to activation by different agonists. The Journal of Biological Chemistry. 282: 36057-67. PMID 17911099 DOI: 10.1074/jbc.M706468200  1
2007 Teper Y, Whyte D, Cahir E, Lester HA, Grady SR, Marks MJ, Cohen BN, Fonck C, McClure-Begley T, McIntosh JM, Labarca C, Lawrence A, Chen F, Gantois I, Davies PJ, et al. Nicotine-induced dystonic arousal complex in a mouse line harboring a human autosomal-dominant nocturnal frontal lobe epilepsy mutation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10128-42. PMID 17881519 DOI: 10.1523/JNEUROSCI.3042-07.2007  1
2007 Tapper AR, McKinney SL, Marks MJ, Lester HA. Nicotine responses in hypersensitive and knockout alpha 4 mice account for tolerance to both hypothermia and locomotor suppression in wild-type mice. Physiological Genomics. 31: 422-8. PMID 17712039 DOI: 10.1152/physiolgenomics.00063.2007  1
2007 Rodriguez EA, Lester HA, Dougherty DA. Improved amber and opal suppressor tRNAs for incorporation of unnatural amino acids in vivo. Part 1: minimizing misacylation. Rna (New York, N.Y.). 13: 1703-14. PMID 17698638 DOI: 10.1261/rna.666807  1
2007 Rodriguez EA, Lester HA, Dougherty DA. Improved amber and opal suppressor tRNAs for incorporation of unnatural amino acids in vivo. Part 2: evaluating suppression efficiency. Rna (New York, N.Y.). 13: 1715-22. PMID 17698637 DOI: 10.1261/rna.667607  1
2007 Nashmi R, Xiao C, Deshpande P, McKinney S, Grady SR, Whiteaker P, Huang Q, McClure-Begley T, Lindstrom JM, Labarca C, Collins AC, Marks MJ, Lester HA. Chronic nicotine cell specifically upregulates functional alpha 4* nicotinic receptors: basis for both tolerance in midbrain and enhanced long-term potentiation in perforant path. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 8202-18. PMID 17670967 DOI: 10.1523/JNEUROSCI.2199-07.2007  1
2007 Nashmi R, Lester H. Cell autonomy, receptor autonomy, and thermodynamics in nicotine receptor up-regulation Biochemical Pharmacology. 74: 1145-1154. PMID 17662697 DOI: 10.1016/j.bcp.2007.06.040  1
2007 Wang J, Lester HA, Dougherty DA. Establishing an ion pair interaction in the homomeric rho1 gamma-aminobutyric acid type A receptor that contributes to the gating pathway. The Journal of Biological Chemistry. 282: 26210-6. PMID 17606618 DOI: 10.1074/jbc.M702314200  1
2007 Jankowsky JL, Younkin LH, Gonzales V, Fadale DJ, Slunt HH, Lester HA, Younkin SG, Borchelt DR. Rodent A beta modulates the solubility and distribution of amyloid deposits in transgenic mice. The Journal of Biological Chemistry. 282: 22707-20. PMID 17556372 DOI: 10.1074/jbc.M611050200  1
2007 Lerchner W, Xiao C, Nashmi R, Slimko EM, van Trigt L, Lester HA, Anderson DJ. Reversible silencing of neuronal excitability in behaving mice by a genetically targeted, ivermectin-gated Cl- channel. Neuron. 54: 35-49. PMID 17408576 DOI: 10.1016/j.neuron.2007.02.030  1
2007 Damaj MI, Fonck C, Marks MJ, Deshpande P, Labarca C, Lester HA, Collins AC, Martin BR. Genetic approaches identify differential roles for alpha4beta2* nicotinic receptors in acute models of antinociception in mice. The Journal of Pharmacology and Experimental Therapeutics. 321: 1161-9. PMID 17371806 DOI: 10.1124/jpet.106.112649  1
2007 Padgett CL, Hanek AP, Lester HA, Dougherty DA, Lummis SC. Unnatural amino acid mutagenesis of the GABA(A) receptor binding site residues reveals a novel cation-pi interaction between GABA and beta 2Tyr97. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 886-92. PMID 17251430 DOI: 10.1523/JNEUROSCI.4791-06.2007  1
2007 Cashin AL, Torrice MM, McMenimen KA, Lester HA, Dougherty DA. Chemical-scale studies on the role of a conserved aspartate in preorganizing the agonist binding site of the nicotinic acetylcholine receptor. Biochemistry. 46: 630-9. PMID 17223685 DOI: 10.1021/bi061638b  1
2006 Nashmi R, Lester HA. CNS localization of neuronal nicotinic receptors. Journal of Molecular Neuroscience : Mn. 30: 181-4. PMID 17192671 DOI: 10.1385/JMN:30:1:181  1
2006 McMenimen KA, Dougherty DA, Lester HA, Petersson EJ. Probing the Mg2+ blockade site of an N-methyl-D-aspartate (NMDA) receptor with unnatural amino acid mutagenesis. Acs Chemical Biology. 1: 227-34. PMID 17163677 DOI: 10.1021/cb6000944  1
2006 Ahern CA, Eastwood AL, Lester HA, Dougherty DA, Horn R. A cation-pi interaction between extracellular TEA and an aromatic residue in potassium channels. The Journal of General Physiology. 128: 649-57. PMID 17130518 DOI: 10.1085/jgp.200609654  1
2006 Miwa JM, Stevens TR, King SL, Caldarone BJ, Ibanez-Tallon I, Xiao C, Fitzsimonds RM, Pavlides C, Lester HA, Picciotto MR, Heintz N. The prototoxin lynx1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival in vivo. Neuron. 51: 587-600. PMID 16950157 DOI: 10.1016/j.neuron.2006.07.025  1
2006 Rodriguez EA, Lester HA, Dougherty DA. In vivo incorporation of multiple unnatural amino acids through nonsense and frameshift suppression. Proceedings of the National Academy of Sciences of the United States of America. 103: 8650-5. PMID 16728509 DOI: 10.1073/pnas.0510817103  1
2006 Schwarz J, Schwarz SC, Dorigo O, Stützer A, Wegner F, Labarca C, Deshpande P, Gil JS, Berk AJ, Lester HA. Enhanced expression of hypersensitive alpha4* nAChR in adult mice increases the loss of midbrain dopaminergic neurons. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 935-46. PMID 16675851 DOI: 10.1096/fj.05-5497com  1
2006 Sokolova IV, Lester HA, Davidson N. Postsynaptic mechanisms are essential for forskolin-induced potentiation of synaptic transmission. Journal of Neurophysiology. 95: 2570-9. PMID 16394076 DOI: 10.1152/jn.00617.2005  1
2005 Fonck C, Cohen BN, Nashmi R, Whiteaker P, Wagenaar DA, Rodrigues-Pinguet N, Deshpande P, McKinney S, Kwoh S, Munoz J, Labarca C, Collins AC, Marks MJ, Lester HA. Novel seizure phenotype and sleep disruptions in knock-in mice with hypersensitive alpha 4* nicotinic receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11396-411. PMID 16339034 DOI: 10.1523/JNEUROSCI.3597-05.2005  1
2005 Lummis SC, Beene DL, Lee LW, Lester HA, Broadhurst RW, Dougherty DA. Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel. Nature. 438: 248-52. PMID 16281040 DOI: 10.1038/nature04130  1
2005 Jankowsky JL, Slunt HH, Gonzales V, Savonenko AV, Wen JC, Jenkins NA, Copeland NG, Younkin LH, Lester HA, Younkin SG, Borchelt DR. Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease. Plos Medicine. 2: e355. PMID 16279840 DOI: 10.1371/journal.pmed.0020355  1
2005 Xiu X, Hanek AP, Wang J, Lester HA, Dougherty DA. A unified view of the role of electrostatic interactions in modulating the gating of Cys loop receptors. The Journal of Biological Chemistry. 280: 41655-66. PMID 16216879 DOI: 10.1074/jbc.M508635200  1
2005 Lummis SC, L Beene D, Harrison NJ, Lester HA, Dougherty DA. A cation-pi binding interaction with a tyrosine in the binding site of the GABAC receptor. Chemistry & Biology. 12: 993-7. PMID 16183023 DOI: 10.1016/j.chembiol.2005.06.012  1
2005 Khakh BS, Fisher JA, Nashmi R, Bowser DN, Lester HA. An angstrom scale interaction between plasma membrane ATP-gated P2X2 and alpha4beta2 nicotinic channels measured with fluorescence resonance energy transfer and total internal reflection fluorescence microscopy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6911-20. PMID 16033901 DOI: 10.1523/JNEUROSCI.0561-05.2005  1
2005 Rodrigues-Pinguet NO, Pinguet TJ, Figl A, Lester HA, Cohen BN. Mutations linked to autosomal dominant nocturnal frontal lobe epilepsy affect allosteric Ca2+ activation of the alpha 4 beta 2 nicotinic acetylcholine receptor. Molecular Pharmacology. 68: 487-501. PMID 15901849 DOI: 10.1124/mol.105.011155  1
2005 Chiu CS, Brickley S, Jensen K, Southwell A, Mckinney S, Cull-Candy S, Mody I, Lester HA. GABA transporter deficiency causes tremor, ataxia, nervousness, and increased GABA-induced tonic conductance in cerebellum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3234-45. PMID 15788781 DOI: 10.1523/JNEUROSCI.3364-04.2005  1
2005 Kovoor A, Seyffarth P, Ebert J, Barghshoon S, Chen CK, Schwarz S, Axelrod JD, Cheyette BN, Simon MI, Lester HA, Schwarz J. D2 dopamine receptors colocalize regulator of G-protein signaling 9-2 (RGS9-2) via the RGS9 DEP domain, and RGS9 knock-out mice develop dyskinesias associated with dopamine pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2157-65. PMID 15728856 DOI: 10.1523/JNEUROSCI.2840-04.2005  1
2005 Cashin AL, Petersson EJ, Lester HA, Dougherty DA. Using physical chemistry to differentiate nicotinic from cholinergic agonists at the nicotinic acetylcholine receptor. Journal of the American Chemical Society. 127: 350-6. PMID 15631485 DOI: 10.1021/ja0461771  1
2005 Nashmi R, Fraser SE, Lester HA, Dickinson ME. FRET Measurements Using Multispectral Imaging Molecular Imaging. 180-192. DOI: 10.1016/B978-019517720-6.50019-5  1
2004 Tapper AR, McKinney SL, Nashmi R, Schwarz J, Deshpande P, Labarca C, Whiteaker P, Marks MJ, Collins AC, Lester HA. Nicotine activation of alpha4* receptors: sufficient for reward, tolerance, and sensitization. Science (New York, N.Y.). 306: 1029-32. PMID 15528443 DOI: 10.1126/science.1099420  1
2004 Diba K, Lester HA, Koch C. Intrinsic noise in cultured hippocampal neurons: experiment and modeling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9723-33. PMID 15509761 DOI: 10.1523/JNEUROSCI.1721-04.2004  1
2004 Beene DL, Price KL, Lester HA, Dougherty DA, Lummis SC. Tyrosine residues that control binding and gating in the 5-hydroxytryptamine3 receptor revealed by unnatural amino acid mutagenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9097-104. PMID 15483128 DOI: 10.1523/JNEUROSCI.2429-04.2004  1
2004 Becker CF, Clayton D, Shapovalov G, Lester HA, Kochendoerfer GG. On-resin assembly of a linkerless lanthanide(III)-based luminescence label and its application to the total synthesis of site-specifically labeled mechanosensitive channels. Bioconjugate Chemistry. 15: 1118-24. PMID 15366968 DOI: 10.1021/bc0498828  1
2004 Shapovalov G, Lester HA. Gating transitions in bacterial ion channels measured at 3 microns resolution. The Journal of General Physiology. 124: 151-61. PMID 15277576 DOI: 10.1085/jgp.200409087  1
2004 Dahan DS, Dibas MI, Petersson EJ, Auyeung VC, Chanda B, Bezanilla F, Dougherty DA, Lester HA. A fluorophore attached to nicotinic acetylcholine receptor beta M2 detects productive binding of agonist to the alpha delta site. Proceedings of the National Academy of Sciences of the United States of America. 101: 10195-200. PMID 15218096 DOI: 10.1073/pnas.0301885101  1
2004 Bhattacharya A, Dang H, Zhu QM, Schnegelsberg B, Rozengurt N, Cain G, Prantil R, Vorp DA, Guy N, Julius D, Ford AP, Lester HA, Cockayne DA. Uropathic observations in mice expressing a constitutively active point mutation in the 5-HT3A receptor subunit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5537-48. PMID 15201326 DOI: 10.1523/JNEUROSCI.5658-03.2004  1
2004 Orb S, Wieacker J, Labarca C, Fonck C, Lester HA, Schwarz J. Knockin mice with Leu9'Ser alpha4-nicotinic receptors: substantia nigra dopaminergic neurons are hypersensitive to agonist and lost postnatally. Physiological Genomics. 18: 299-307. PMID 15199190 DOI: 10.1152/physiolgenomics.00012.2004  1
2004 Lester HA, Dibas MI, Dahan DS, Leite JF, Dougherty DA. Cys-loop receptors: new twists and turns. Trends in Neurosciences. 27: 329-36. PMID 15165737 DOI: 10.1016/j.tins.2004.04.002  1
2004 Clayton D, Shapovalov G, Maurer JA, Dougherty DA, Lester HA, Kochendoerfer GG. Total chemical synthesis and electrophysiological characterization of mechanosensitive channels from Escherichia coli and Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 101: 4764-9. PMID 15041744 DOI: 10.1073/pnas.0305693101  1
2003 Owens JC, Balogh SA, McClure-Begley TD, Butt CM, Labarca C, Lester HA, Picciotto MR, Wehner JM, Collins AC. Alpha 4 beta 2* nicotinic acetylcholine receptors modulate the effects of ethanol and nicotine on the acoustic startle response. Alcoholism, Clinical and Experimental Research. 27: 1867-75. PMID 14691373 DOI: 10.1097/01.ALC.0000102700.72447.0F  1
2003 Nashmi R, Dickinson ME, McKinney S, Jareb M, Labarca C, Fraser SE, Lester HA. Assembly of alpha4beta2 nicotinic acetylcholine receptors assessed with functional fluorescently labeled subunits: effects of localization, trafficking, and nicotine-induced upregulation in clonal mammalian cells and in cultured midbrain neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 11554-67. PMID 14684858  1
2003 Gutman GA, Chandy KG, Adelman JP, Aiyar J, Bayliss DA, Clapham DE, Covarriubias M, Desir GV, Furuichi K, Ganetzky B, Garcia ML, Grissmer S, Jan LY, Karschin A, Kim D, ... ... Lester HA, et al. International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels. Pharmacological Reviews. 55: 583-6. PMID 14657415 DOI: 10.1124/pr.55.4.9  1
2003 Storch A, Lester HA, Boehm BO, Schwarz J. Functional characterization of dopaminergic neurons derived from rodent mesencephalic progenitor cells. Journal of Chemical Neuroanatomy. 26: 133-42. PMID 14599663 DOI: 10.1016/S0891-0618(03)00067-X  1
2003 Lester HA, Fonck C, Tapper AR, McKinney S, Damaj MI, Balogh S, Owens J, Wehner JM, Collins AC, Labarca C. Hypersensitive knockin mouse strains identify receptors and pathways for nicotine action. Current Opinion in Drug Discovery & Development. 6: 633-9. PMID 14579512  1
2003 Leite JF, Blanton MP, Shahgholi M, Dougherty DA, Lester HA. Conformation-dependent hydrophobic photolabeling of the nicotinic receptor: electrophysiology-coordinated photochemistry and mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America. 100: 13054-9. PMID 14569028 DOI: 10.1073/pnas.2133028100  1
2003 Leite JF, Dougherty DA, Lester HA, Shahgholi M. Investigation of apparent mass deviations in electrospray ionization tandem mass spectrometry of a benzophenone-labeled peptide. Rapid Communications in Mass Spectrometry : Rcm. 17: 1677-84. PMID 12872270 DOI: 10.1002/rcm.1103  1
2003 Beene DL, Dougherty DA, Lester HA. Unnatural amino acid mutagenesis in mapping ion channel function. Current Opinion in Neurobiology. 13: 264-70. PMID 12850209 DOI: 10.1016/S0959-4388(03)00068-0  1
2003 Monahan SL, Lester HA, Dougherty DA. Site-specific incorporation of unnatural amino acids into receptors expressed in Mammalian cells. Chemistry & Biology. 10: 573-80. PMID 12837390 DOI: 10.1016/S1074-5521(03)00124-8  1
2003 Rahman Z, Schwarz J, Gold SJ, Zachariou V, Wein MN, Choi KH, Kovoor A, Chen CK, DiLeone RJ, Schwarz SC, Selley DE, Sim-Selley LJ, Barrot M, Luedtke RR, Self D, ... ... Lester HA, et al. RGS9 modulates dopamine signaling in the basal ganglia. Neuron. 38: 941-52. PMID 12818179 DOI: 10.1016/S0896-6273(03)00321-0  1
2003 Jensen K, Chiu CS, Sokolova I, Lester HA, Mody I. GABA transporter-1 (GAT1)-deficient mice: differential tonic activation of GABAA versus GABAB receptors in the hippocampus. Journal of Neurophysiology. 90: 2690-701. PMID 12815026 DOI: 10.1152/jn.00240.2003  1
2003 Mu TW, Lester HA, Dougherty DA. Different binding orientations for the same agonist at homologous receptors: a lock and key or a simple wedge? Journal of the American Chemical Society. 125: 6850-1. PMID 12783521 DOI: 10.1021/ja0348086  1
2003 Rodrigues-Pinguet N, Jia L, Li M, Figl A, Klaassen A, Truong A, Lester HA, Cohen BN. Five ADNFLE mutations reduce the Ca2+ dependence of the mammalian alpha4beta2 acetylcholine response. The Journal of Physiology. 550: 11-26. PMID 12754307 DOI: 10.1113/jphysiol.2002.036681  1
2003 Yu TP, Lester HA, Davidson N. Requirement of a critical period of GABAergic receptor blockade for induction of a cAMP-mediated long-term depression at CA3-CA1 synapses. Synapse (New York, N.Y.). 49: 12-9. PMID 12710011 DOI: 10.1002/syn.10207  1
2003 Fonck C, Nashmi R, Deshpande P, Damaj MI, Marks MJ, Riedel A, Schwarz J, Collins AC, Labarca C, Lester HA. Increased sensitivity to agonist-induced seizures, straub tail, and hippocampal theta rhythm in knock-in mice carrying hypersensitive alpha 4 nicotinic receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2582-90. PMID 12684443  1
2003 Shapovalov G, Bass R, Rees DC, Lester HA. Open-state disulfide crosslinking between Mycobacterium tuberculosis mechanosensitive channel subunits. Biophysical Journal. 84: 2357-65. PMID 12668444 DOI: 10.1016/S0006-3495(03)75041-3  1
2003 Slimko EM, Lester HA. Codon optimization of Caenorhabditis elegans GluCl ion channel genes for mammalian cells dramatically improves expression levels. Journal of Neuroscience Methods. 124: 75-81. PMID 12648766 DOI: 10.1016/S0165-0270(02)00362-X  1
2003 Petersson EJ, Brandt GS, Zacharias NM, Dougherty DA, Lester HA. Caging proteins through unnatural amino acid mutagenesis. Methods in Enzymology. 360: 258-73. PMID 12622154 DOI: 10.1016/S0076-6879(03)60114-X  1
2003 Rozengurt N, Lopez I, Chiu CS, Kofuji P, Lester HA, Neusch C. Time course of inner ear degeneration and deafness in mice lacking the Kir4.1 potassium channel subunit. Hearing Research. 177: 71-80. PMID 12618319 DOI: 10.1016/S0378-5955(02)00799-2  1
2003 Leite JF, Rodrigues-Pinguet N, Lester HA. Insights into channel function via channel dysfunction. The Journal of Clinical Investigation. 111: 436-7. PMID 12588879 DOI: 10.1172/JCI17882  1
2003 Nashmi R, Dickinson ME, McKinney S, Jareb M, Labarca C, Fraser SE, Lester HA. Assembly of α4β2 Nicotinic Acetylcholine Receptors Assessed with Functional Fluorescently Labeled Subunits: Effects of Localization, Trafficking, and Nicotine-Induced Upregulation in Clonal Mammalian Cells and in Cultured Midbrain Neurons Journal of Neuroscience. 23: 11554-11567.  1
2002 Chiu CS, Jensen K, Sokolova I, Wang D, Li M, Deshpande P, Davidson N, Mody I, Quick MW, Quake SR, Lester HA. Number, density, and surface/cytoplasmic distribution of GABA transporters at presynaptic structures of knock-in mice carrying GABA transporter subtype 1-green fluorescent protein fusions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10251-66. PMID 12451126  1
2002 Petersson EJ, Choi A, Dahan DS, Lester HA, Dougherty DA. A perturbed pK(a) at the binding site of the nicotinic acetylcholine receptor: implications for nicotine binding. Journal of the American Chemical Society. 124: 12662-3. PMID 12392404  1
2002 Li P, Slimko EM, Lester HA. Selective elimination of glutamate activation and introduction of fluorescent proteins into a Caenorhabditis elegans chloride channel. Febs Letters. 528: 77-82. PMID 12297283 DOI: 10.1016/S0014-5793(02)03245-3  1
2002 Slimko EM, McKinney S, Anderson DJ, Davidson N, Lester HA. Selective electrical silencing of mammalian neurons in vitro by the use of invertebrate ligand-gated chloride channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 7373-9. PMID 12196558  1
2002 Beene DL, Brandt GS, Zhong W, Zacharias NM, Lester HA, Dougherty DA. Cation-pi interactions in ligand recognition by serotonergic (5-HT3A) and nicotinic acetylcholine receptors: the anomalous binding properties of nicotine. Biochemistry. 41: 10262-9. PMID 12162741 DOI: 10.1021/bi020266d  1
2002 Eickhorst AN, Berson A, Cockayne D, Lester HA, Khakh BS. Control of P2X(2) channel permeability by the cytosolic domain. The Journal of General Physiology. 120: 119-31. PMID 12149275 DOI: 10.1085/jgp.20028535  1
2002 Nadeau H, Lester HA. NRSF causes cAMP-sensitive suppression of sodium current in cultured hippocampal neurons. Journal of Neurophysiology. 88: 409-21. PMID 12091564  1
2002 Li M, Lester HA. Early fluorescence signals detect transitions at mammalian serotonin transporters. Biophysical Journal. 83: 206-18. PMID 12080113 DOI: 10.1016/S0006-3495(02)75162-X  1
2002 Petersson EJ, Shahgholi M, Lester HA, Dougherty DA. MALDI-TOF mass spectrometry methods for evaluation of in vitro aminoacyl tRNA production. Rna (New York, N.Y.). 8: 542-7. PMID 11991647 DOI: 10.1017/S1355838202026146  1
2002 Li M, Farley RA, Lester HA. Voltage-dependent transient currents of human and rat 5-HT transporters (SERT) are blocked by HEPES and ion channel ligands. Febs Letters. 513: 247-52. PMID 11904159 DOI: 10.1016/S0014-5793(02)02322-0  1
2002 Kovoor A, Lester HA. Gi Irks GIRKs. Neuron. 33: 6-8. PMID 11779473 DOI: 10.1016/S0896-6273(01)00572-4  1
2002 Petersson EJ, Choi A, Dahan DS, Lester HA, Dougherty DA. A perturbed pKa at the binding site of the nicotinic acetylcholine receptor: Implications for nicotine binding Journal of the American Chemical Society. 124: 12662-12663. DOI: 10.1021/ja028206i  1
2001 Li M, Lester HA. Ion channel diseases of the central nervous system. Cns Drug Reviews. 7: 214-40. PMID 11474425  1
2001 Neusch C, Rozengurt N, Jacobs RE, Lester HA, Kofuji P. Kir4.1 potassium channel subunit is crucial for oligodendrocyte development and in vivo myelination. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 5429-38. PMID 11466414  1
2001 Philipson KD, Gallivan JP, Brandt GS, Dougherty DA, Lester HA. Incorporation of caged cysteine and caged tyrosine into a transmembrane segment of the nicotinic ACh receptor. American Journal of Physiology. Cell Physiology. 281: C195-206. PMID 11401842  1
2001 Dougherty DA, Lester HA. Neurobiology. Snails, synapses and smokers. Nature. 411: 252-3, 255. PMID 11357112 DOI: 10.1038/35077192  1
2001 Yu TP, McKinney S, Lester HA, Davidson N. Gamma-aminobutyric acid type A receptors modulate cAMP-mediated long-term potentiation and long-term depression at monosynaptic CA3-CA1 synapses. Proceedings of the National Academy of Sciences of the United States of America. 98: 5264-9. PMID 11296264 DOI: 10.1073/pnas.091093998  1
2001 Khakh BS, Smith WB, Chiu CS, Ju D, Davidson N, Lester HA. Activation-dependent changes in receptor distribution and dendritic morphology in hippocampal neurons expressing P2X2-green fluorescent protein receptors. Proceedings of the National Academy of Sciences of the United States of America. 98: 5288-93. PMID 11296257 DOI: 10.1073/pnas.081089198  1
2001 Labarca C, Schwarz J, Deshpande P, Schwarz S, Nowak MW, Fonck C, Nashmi R, Kofuji P, Dang H, Shi W, Fidan M, Khakh BS, Chen Z, Bowers BJ, Boulter J, ... ... Lester HA, et al. Point mutant mice with hypersensitive alpha 4 nicotinic receptors show dopaminergic deficits and increased anxiety. Proceedings of the National Academy of Sciences of the United States of America. 98: 2786-91. PMID 11226318 DOI: 10.1073/pnas.041582598  1
2001 Li L, Zhong W, Zacharias N, Gibbs C, Lester HA, Dougherty DA. The tethered agonist approach to mapping ion channel proteins--toward a structural model for the agonist binding site of the nicotinic acetylcholine receptor. Chemistry & Biology. 8: 47-58. PMID 11182318 DOI: 10.1016/S1074-5521(00)00055-7  1
2001 Chiu CS, Kartalov E, Unger M, Quake S, Lester HA. Single-molecule measurements calibrate green fluorescent protein surface densities on transparent beads for use with 'knock-in' animals and other expression systems. Journal of Neuroscience Methods. 105: 55-63. PMID 11166366 DOI: 10.1016/S0165-0270(00)00354-X  1
2001 Tong Y, Brandt GS, Li M, Shapovalov G, Slimko E, Karschin A, Dougherty DA, Lester HA. Tyrosine decaging leads to substantial membrane trafficking during modulation of an inward rectifier potassium channel. The Journal of General Physiology. 117: 103-18. PMID 11158164 DOI: 10.1085/jgp.117.2.103  1
2001 Dougherty DA, Lester HA. Snails, synapses and smokers Nature. 411: 252-255.  1
2000 Ehrengruber MU, Muhlebach SG, Söhrman S, Leutenegger CM, Lester HA, Davidson N. Modulation of early growth response (EGR) transcription factor-dependent gene expression by using recombinant adenovirus. Gene. 258: 63-9. PMID 11111043 DOI: 10.1016/S0378-1119(00)00445-5  1
2000 Chiu C, Ross LS, Cohen BN, Lester HA, Gill SS. The transporter-like protein inebriated mediates hyperosmotic stimuli through intracellular signaling. The Journal of Experimental Biology. 203: 3531-46. PMID 11060215  1
2000 Nadeau H, McKinney S, Anderson DJ, Lester HA. ROMK1 (Kir1.1) causes apoptosis and chronic silencing of hippocampal neurons. Journal of Neurophysiology. 84: 1062-75. PMID 10938328  1
2000 Nadeau H, Lester HA. Two-compartment model for whole-cell data analysis and transient compensation. Journal of Neuroscience Methods. 99: 25-35. PMID 10936639 DOI: 10.1016/S0165-0270(00)00210-7  1
2000 Khakh BS, Zhou X, Sydes J, Galligan JJ, Lester HA. State-dependent cross-inhibition between transmitter-gated cation channels. Nature. 406: 405-10. PMID 10935636 DOI: 10.1038/35019066  1
2000 Kofuji P, Ceelen P, Zahs KR, Surbeck LW, Lester HA, Newman EA. Genetic inactivation of an inwardly rectifying potassium channel (Kir4.1 subunit) in mice: phenotypic impact in retina. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5733-40. PMID 10908613  1
2000 Lester HA, Karschin A. Gain of function mutants: ion channels and G protein-coupled receptors. Annual Review of Neuroscience. 23: 89-125. PMID 10845060 DOI: 10.1146/annurev.neuro.23.1.89  1
2000 Dang H, England PM, Farivar SS, Dougherty DA, Lester HA. Probing the role of a conserved M1 proline residue in 5-hydroxytryptamine(3) receptor gating. Molecular Pharmacology. 57: 1114-22. PMID 10825381  1
2000 Maurer JA, Elmore DE, Lester HA, Dougherty DA. Comparing and contrasting Escherichia coli and Mycobacterium tuberculosis mechanosensitive channels (MscL). New gain of function mutations in the loop region. The Journal of Biological Chemistry. 275: 22238-44. PMID 10801868 DOI: 10.1074/jbc.M003056200  1
2000 Li M, Farley RA, Lester HA. An intermediate state of the gamma-aminobutyric acid transporter GAT1 revealed by simultaneous voltage clamp and fluorescence. The Journal of General Physiology. 115: 491-508. PMID 10736315 DOI: 10.1085/jgp.115.4.491  1
2000 Ivanina T, Neusch C, Li YX, Tong Y, Labarca C, Mosher DF, Lester HA. Expression of GIRK (Kir3.1/Kir3.4) channels in mouse fibroblast cells with and without beta1 integrins. Febs Letters. 466: 327-32. PMID 10682853 DOI: 10.1016/S0014-5793(99)01738-X  1
2000 Kovoor A, Chen CK, He W, Wensel TG, Simon MI, Lester HA. Co-expression of Gbeta5 enhances the function of two Ggamma subunit-like domain-containing regulators of G protein signaling proteins. The Journal of Biological Chemistry. 275: 3397-402. PMID 10652332  1
2000 Kovoor A, Chen CK, He W, Wensel TG, Simon MI, Lester HA. Co-expression of Gβ5 enhances the function of two Gγ subunit-like domain-containing regulators of G protein signaling proteins Journal of Biological Chemistry. 275: 3397-3402. DOI: 10.1074/jbc.275.5.3397  1
1999 Unger M, Kartalov E, Chiu CS, Lester HA, Quake SR. Single-molecule fluorescence observed with mercury lamp illumination. Biotechniques. 27: 1008-14. PMID 10572649  1
1999 England PM, Lester HA, Dougherty DA. Mapping disulfide connectivity using backbone ester hydrolysis. Biochemistry. 38: 14409-15. PMID 10572015 DOI: 10.1021/bi991424c  1
1999 Khakh BS, Lester HA. Dynamic selectivity filters in ion channels. Neuron. 23: 653-8. PMID 10482233 DOI: 10.1016/S0896-6273(01)80025-8  1
1999 Khakh BS, Proctor WR, Dunwiddie TV, Labarca C, Lester HA. Allosteric control of gating and kinetics at P2X(4) receptor channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 7289-99. PMID 10460235  1
1999 Li J, Lester HA. Single-channel kinetics of the rat olfactory cyclic nucleotide-gated channel expressed in Xenopus oocytes. Molecular Pharmacology. 55: 883-93. PMID 10220567  1
1999 Li J, Lester HA. Functional roles of aromatic residues in the ligand-binding domain of cyclic nucleotide-gated channels. Molecular Pharmacology. 55: 873-82. PMID 10220566  1
1999 Khakh BS, Bao XR, Labarca C, Lester HA. Neuronal P2X transmitter-gated cation channels change their ion selectivity in seconds. Nature Neuroscience. 2: 322-30. PMID 10204538 DOI: 10.1038/7233  1
1999 England PM, Zhang Y, Dougherty DA, Lester HA. Backbone mutations in transmembrane domains of a ligand-gated ion channel: implications for the mechanism of gating. Cell. 96: 89-98. PMID 9989500 DOI: 10.1016/S0092-8674(00)80962-9  1
1999 England PM, Lester HA, Dougherty DA. Incorporation of esters into proteins: Improved synthesis of hydroxyacyl tRNAs Tetrahedron Letters. 40: 6189-6192. DOI: 10.1016/S0040-4039(99)01300-3  1
1998 Dougherty DA, Lester HA. The Crystal Structure of a Potassium Channel- A New Era in the Chemistry of Biological Signaling. Angewandte Chemie (International Ed. in English). 37: 2329-2331. PMID 29710958 DOI: 10.1002/(SICI)1521-3773(19980918)37:17<2329::AID-ANIE2329>3.0.CO;2-M  1
1998 McPhee JC, Dang YL, Davidson N, Lester HA. Evidence for a functional interaction between integrins and G protein-activated inward rectifier K+ channels. The Journal of Biological Chemistry. 273: 34696-702. PMID 9856991 DOI: 10.1074/jbc.273.52.34696  1
1998 Li YX, Zhang Y, Lester HA, Schuman EM, Davidson N. Enhancement of neurotransmitter release induced by brain-derived neurotrophic factor in cultured hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 10231-40. PMID 9852560  1
1998 Mager S, Cao Y, Lester HA. Measurement of transient currents from neurotransmitter transporters expressed in Xenopus oocytes. Methods in Enzymology. 296: 551-66. PMID 9779473 DOI: 10.1016/S0076-6879(98)96039-6  1
1998 Zhong W, Gallivan JP, Zhang Y, Li L, Lester HA, Dougherty DA. From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor. Proceedings of the National Academy of Sciences of the United States of America. 95: 12088-93. PMID 9770444 DOI: 10.1073/pnas.95.21.12088  1
1998 Cao Y, Li M, Mager S, Lester HA. Amino acid residues that control pH modulation of transport-associated current in mammalian serotonin transporters. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 7739-49. PMID 9742144  1
1998 Silverman SK, Lester HA, Dougherty DA. Asymmetrical contributions of subunit pore regions to ion selectivity in an inward rectifier K+ channel. Biophysical Journal. 75: 1330-9. PMID 9726934 DOI: 10.1016/S0006-3495(98)74051-2  1
1998 Li YX, Xu Y, Ju D, Lester HA, Davidson N, Schuman EM. Expression of a dominant negative TrkB receptor, T1, reveals a requirement for presynaptic signaling in BDNF-induced synaptic potentiation in cultured hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. 95: 10884-9. PMID 9724799 DOI: 10.1073/pnas.95.18.10884  1
1998 Nowak MW, Gallivan JP, Silverman SK, Labarca CG, Dougherty DA, Lester HA. In vivo incorporation of unnatural amino acids into ion channels in Xenopus oocyte expression system. Methods in Enzymology. 293: 504-29. PMID 9711626 DOI: 10.1016/S0076-6879(98)93031-2  1
1998 Ehrengruber MU, Lanzrein M, Xu Y, Jasek MC, Kantor DB, Schuman EM, Lester HA, Davidson N. Recombinant adenovirus-mediated expression in nervous system of genes coding for ion channels and other molecules involved in synaptic function. Methods in Enzymology. 293: 483-503. PMID 9711625 DOI: 10.1016/S0076-6879(98)93030-0  1
1998 Yu N, Cao Y, Mager S, Lester HA. Topological localization of cysteine 74 in the GABA transporter, GAT1, and its importance in ion binding and permeation. Febs Letters. 426: 174-8. PMID 9599002 DOI: 10.1016/S0014-5793(98)00333-0  1
1998 Miller JC, Silverman SK, England PM, Dougherty DA, Lester HA. Flash decaging of tyrosine sidechains in an ion channel. Neuron. 20: 619-24. PMID 9581754 DOI: 10.1016/S0896-6273(00)81001-6  1
1998 Lester HA, Dougherty DA. New views of multi-ion channels. The Journal of General Physiology. 111: 181-3. PMID 9450937  1
1998 Dougherty DA, Lester HA. The crystal structure of a potassium channel - A new era in the chemistry of biological signaling Angewandte Chemie - International Edition. 37: 2329-2331. DOI: 10.1002/(SICI)1521-3773(19980918)37:17<2329::AID-ANIE2329>3.0.CO;2-M  1
1997 Luchian T, Dascal N, Dessauer C, Platzer D, Davidson N, Lester HA, Schreibmayer W. A C-terminal peptide of the GIRK1 subunit directly blocks the G protein-activated K+ channel (GIRK) expressed in Xenopus oocytes. The Journal of Physiology. 505: 13-22. PMID 9409468  1
1997 England PM, Lester HA, Davidson N, Dougherty DA. Site-specific, photochemical proteolysis applied to ion channels in vivo. Proceedings of the National Academy of Sciences of the United States of America. 94: 11025-30. PMID 9380753 DOI: 10.1073/pnas.94.20.11025  1
1997 Gallivan JP, Lester HA, Dougherty DA. Site-specific incorporation of biotinylated amino acids to identify surface-exposed residues in integral membrane proteins. Chemistry & Biology. 4: 739-49. PMID 9375252  1
1997 West AP, Bjorkman PJ, Dougherty DA, Lester HA. Expression and circular dichroism studies of the extracellular domain of the alpha subunit of the nicotinic acetylcholine receptor. The Journal of Biological Chemistry. 272: 25468-73. PMID 9325259 DOI: 10.1074/jbc.272.41.25468  1
1997 Doupnik CA, Davidson N, Lester HA, Kofuji P. RGS proteins reconstitute the rapid gating kinetics of gbetagamma-activated inwardly rectifying K+ channels. Proceedings of the National Academy of Sciences of the United States of America. 94: 10461-6. PMID 9294233 DOI: 10.1073/pnas.94.19.10461  1
1997 Li J, Zagotta WN, Lester HA. Cyclic nucleotide-gated channels: structural basis of ligand efficacy and allosteric modulation. Quarterly Reviews of Biophysics. 30: 177-93. PMID 9293605 DOI: 10.1017/S0033583597003326  1
1997 Ehrengruber MU, Doupnik CA, Xu Y, Garvey J, Jasek MC, Lester HA, Davidson N. Activation of heteromeric G protein-gated inward rectifier K+ channels overexpressed by adenovirus gene transfer inhibits the excitability of hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. 94: 7070-5. PMID 9192693 DOI: 10.1073/pnas.94.13.7070  1
1997 Quick MW, Corey JL, Davidson N, Lester HA. Second messengers, trafficking-related proteins, and amino acid residues that contribute to the functional regulation of the rat brain GABA transporter GAT1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 2967-79. PMID 9096133  1
1997 Cao Y, Mager S, Lester HA. H+ permeation and pH regulation at a mammalian serotonin transporter. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 2257-66. PMID 9065487  1
1997 Bradley J, Zhang Y, Bakin R, Lester HA, Ronnett GV, Zinn K. Functional expression of the heteromeric "olfactory" cyclic nucleotide-gated channel in the hippocampus: a potential effector of synaptic plasticity in brain neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 1993-2005. PMID 9045728  1
1996 Silverman SK, Kofuji P, Dougherty DA, Davidson N, Lester HA. A regenerative link in the ionic fluxes through the weaver potassium channel underlies the pathophysiology of the mutation. Proceedings of the National Academy of Sciences of the United States of America. 93: 15429-34. PMID 8986828 DOI: 10.1073/pnas.93.26.15429  1
1996 Kearney PC, Zhang H, Zhong W, Dougherty DA, Lester HA. Determinants of nicotinic receptor gating in natural and unnatural side chain structures at the M2 9' position. Neuron. 17: 1221-9. PMID 8982168 DOI: 10.1016/S0896-6273(00)80252-4  1
1996 Lin F, Lester HA, Mager S. Single-channel currents produced by the serotonin transporter and analysis of a mutation affecting ion permeation. Biophysical Journal. 71: 3126-35. PMID 8968583 DOI: 10.1016/S0006-3495(96)79506-1  1
1996 Quick MW, Lester HA, Davidson N, Simon MI, Aragay AM. Desensitization of inositol 1,4,5-trisphosphate/Ca2+-induced Cl- currents by prolonged activation of G proteins in Xenopus oocytes. The Journal of Biological Chemistry. 271: 32021-7. PMID 8943251 DOI: 10.1074/jbc.271.50.32021  1
1996 Silverman SK, Lester HA, Dougherty DA. Subunit stoichiometry of a heteromultimeric G protein-coupled inward-rectifier K+ channel. The Journal of Biological Chemistry. 271: 30524-8. PMID 8940021 DOI: 10.1074/jbc.271.48.30524  1
1996 Doupnik CA, Dessauer CW, Slepak VZ, Gilman AG, Davidson N, Lester HA. Time resolved kinetics of direct G beta 1 gamma 2 interactions with the carboxyl terminus of Kir3.4 inward rectifier K+ channel subunits. Neuropharmacology. 35: 923-31. PMID 8938723 DOI: 10.1016/0028-3908(96)00125-6  1
1996 Lester HA, Cao Y, Mager S. Listening to neurotransmitter transporters. Neuron. 17: 807-10. PMID 8938113 DOI: 10.1016/S0896-6273(00)80213-5  1
1996 Kearney PC, Nowak MW, Zhong W, Silverman SK, Lester HA, Dougherty DA. Dose-response relations for unnatural amino acids at the agonist binding site of the nicotinic acetylcholine receptor: tests with novel side chains and with several agonists. Molecular Pharmacology. 50: 1401-12. PMID 8913372  1
1996 Figl A, Labarca C, Davidson N, Lester HA, Cohen BN. Voltage-jump relaxation kinetics for wild-type and chimeric beta subunits of neuronal nicotinic receptors. The Journal of General Physiology. 107: 369-79. PMID 8868048 DOI: 10.1085/jgp.107.3.369  1
1996 Saks ME, Sampson JR, Nowak MW, Kearney PC, Du F, Abelson JN, Lester HA, Dougherty DA. An engineered Tetrahymena tRNAGln for in vivo incorporation of unnatural amino acids into proteins by nonsense suppression. The Journal of Biological Chemistry. 271: 23169-75. PMID 8798511 DOI: 10.1074/jbc.271.38.23169  1
1996 Su A, Mager S, Mayo SL, Lester HA. A multi-substrate single-file model for ion-coupled transporters. Biophysical Journal. 70: 762-77. PMID 8789093 DOI: 10.1016/S0006-3495(96)79616-9  1
1996 Mager S, Kleinberger-Doron N, Keshet GI, Davidson N, Kanner BI, Lester HA. Ion binding and permeation at the GABA transporter GAT1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 5405-14. PMID 8757253  1
1996 Kofuji P, Doupnik CA, Davidson N, Lester HA. A unique P-region residue is required for slow voltage-dependent gating of a G protein-activated inward rectifier K+ channel expressed in Xenopus oocytes. The Journal of Physiology. 490: 633-45. PMID 8683463  1
1996 Kofuji P, Hofer M, Millen KJ, Millonig JH, Davidson N, Lester HA, Hatten ME. Functional analysis of the weaver mutant GIRK2 K+ channel and rescue of weaver granule cells. Neuron. 16: 941-52. PMID 8630252 DOI: 10.1016/S0896-6273(00)80117-8  1
1996 Schreibmayer W, Dessauer CW, Vorobiov D, Gilman AG, Lester HA, Davidson N, Dascal N. Inhibition of an inwardly rectifying K+ channel by G-protein alpha-subunits. Nature. 380: 624-7. PMID 8602262 DOI: 10.1038/380624a0  1
1996 DiMagno L, Dascal N, Davidson N, Lester HA, Schreibmayer W. Serotonin and protein kinase C modulation of a rat brain inwardly rectifying K+ channel expressed in xenopus oocytes. PflüGers Archiv : European Journal of Physiology. 431: 335-40. PMID 8584426 DOI: 10.1007/BF02207270  1
1995 Bausch SB, Patterson TA, Ehrengruber MU, Lester HA, Davidson N, Chavkin C. Colocalization of mu opioid receptors with GIRK1 potassium channels in the rat brain: an immunocytochemical study. Receptors & Channels. 3: 221-41. PMID 8821795  1
1995 Lim NF, Dascal N, Labarca C, Davidson N, Lester HA. A G protein-gated K channel is activated via beta 2-adrenergic receptors and G beta gamma subunits in Xenopus oocytes. The Journal of General Physiology. 105: 421-39. PMID 7769382 DOI: 10.1085/jgp.105.3.421  1
1995 Henry DJ, Grandy DK, Lester HA, Davidson N, Chavkin C. Kappa-opioid receptors couple to inwardly rectifying potassium channels when coexpressed by Xenopus oocytes. Molecular Pharmacology. 47: 551-7. PMID 7700253  1
1995 Keshet GI, Bendahan A, Su H, Mager S, Lester HA, Kanner BI. Glutamate-101 is critical for the function of the sodium and chloride-coupled GABA transporter GAT-1. Febs Letters. 371: 39-42. PMID 7664880 DOI: 10.1016/0014-5793(95)00859-8  1
1995 Labarca C, Nowak MW, Zhang H, Tang L, Deshpande P, Lester HA. Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors. Nature. 376: 514-6. PMID 7637783 DOI: 10.1038/376514a0  1
1995 Kofuji P, Davidson N, Lester HA. Evidence that neuronal G-protein-gated inwardly rectifying K+ channels are activated by G beta gamma subunits and function as heteromultimers. Proceedings of the National Academy of Sciences of the United States of America. 92: 6542-6. PMID 7604029 DOI: 10.1073/pnas.92.14.6542  1
1995 Doupnik CA, Davidson N, Lester HA. The inward rectifier potassium channel family. Current Opinion in Neurobiology. 5: 268-77. PMID 7580148 DOI: 10.1016/0959-4388(95)80038-7  1
1995 Cohen BN, Figl A, Quick MW, Labarca C, Davidson N, Lester HA. Regions of beta 2 and beta 4 responsible for differences between the steady state dose-response relationships of the alpha 3 beta 2 and alpha 3 beta 4 neuronal nicotinic receptors. The Journal of General Physiology. 105: 745-64. PMID 7561742 DOI: 10.1085/jgp.105.6.745  1
1995 Dascal N, Doupnik CA, Ivanina T, Bausch S, Wang W, Lin C, Garvey J, Chavkin C, Lester HA, Davidson N. Inhibition of function in Xenopus oocytes of the inwardly rectifying G-protein-activated atrial K channel (GIRK1) by overexpression of a membrane-attached form of the C-terminal tail. Proceedings of the National Academy of Sciences of the United States of America. 92: 6758-62. PMID 7542774  1
1995 Doupnik CA, Lim NF, Kofuji P, Davidson N, Lester HA. Intrinsic gating properties of a cloned G protein-activated inward rectifier K+ channel. The Journal of General Physiology. 106: 1-23. PMID 7494135 DOI: 10.1085/jgp.106.1.1  1
1994 Corey JL, Quick MW, Davidson N, Lester HA, Guastella J. A cocaine-sensitive Drosophila serotonin transporter: cloning, expression, and electrophysiological characterization. Proceedings of the National Academy of Sciences of the United States of America. 91: 1188-92. PMID 8302852  1
1994 Corey JL, Davidson N, Lester HA, Brecha N, Quick MW. Protein kinase C modulates the activity of a cloned gamma-aminobutyric acid transporter expressed in Xenopus oocytes via regulated subcellular redistribution of the transporter. The Journal of Biological Chemistry. 269: 14759-67. PMID 8182081  1
1994 Mager S, Min C, Henry DJ, Chavkin C, Hoffman BJ, Davidson N, Lester HA. Conducting states of a mammalian serotonin transporter. Neuron. 12: 845-59. PMID 8161456 DOI: 10.1016/0896-6273(94)90337-9  1
1994 Corey JL, Guastella J, Davidson N, Lester HA. GABA uptake and release by a mammalian cell line stably expressing a cloned rat brain GABA transporter. Molecular Membrane Biology. 11: 23-30. PMID 8019597 DOI: 10.3109/09687689409161026  1
1994 Quick MW, Simon MI, Davidson N, Lester HA, Aragay AM. Differential coupling of G protein alpha subunits to seven-helix receptors expressed in Xenopus oocytes. The Journal of Biological Chemistry. 269: 30164-72. PMID 7982922  1
1994 Lester HA, Mager S, Quick MW, Corey JL. Permeation properties of neurotransmitter transporters. Annual Review of Pharmacology and Toxicology. 34: 219-49. PMID 7913802 DOI: 10.1146/annurev.pa.34.040194.001251  1
1994 Karschin A, Wischmeyer E, Davidson N, Lester HA. Fast inhibition of inwardly rectifying K+ channels by multiple neurotransmitter receptors in oligodendroglia. The European Journal of Neuroscience. 6: 1756-64. PMID 7874315 DOI: 10.1111/j.1460-9568.1994.tb00568.x  1
1994 Schreibmayer W, Frohnwieser B, Dascal N, Platzer D, Spreitzer B, Zechner R, Kallen RG, Lester HA. Beta-adrenergic modulation of currents produced by rat cardiac Na+ channels expressed in Xenopus laevis oocytes. Receptors & Channels. 2: 339-50. PMID 7536612  1
1994 McDonough S, Davidson N, Lester HA, McCarty NA. Novel pore-lining residues in CFTR that govern permeation and open-channel block. Neuron. 13: 623-34. PMID 7522483 DOI: 10.1016/0896-6273(94)90030-2  1
1994 Bradley J, Li J, Davidson N, Lester HA, Zinn K. Heteromeric olfactory cyclic nucleotide-gated channels: a subunit that confers increased sensitivity to cAMP. Proceedings of the National Academy of Sciences of the United States of America. 91: 8890-4. PMID 7522325 DOI: 10.1073/pnas.91.19.8890  1
1994 Schreibmayer W, Lester HA, Dascal N. Voltage clamping of Xenopus laevis oocytes utilizing agarose-cushion electrodes. PflüGers Archiv : European Journal of Physiology. 426: 453-8. PMID 7517034 DOI: 10.1007/BF00388310  1
1993 Slepak VZ, Quick MW, Aragay AM, Davidson N, Lester HA, Simon MI. Random mutagenesis of G protein alpha subunit G(o)alpha. Mutations altering nucleotide binding. The Journal of Biological Chemistry. 268: 21889-94. PMID 8408043  1
1993 McCarty NA, McDonough S, Cohen BN, Riordan JR, Davidson N, Lester HA. Voltage-dependent block of the cystic fibrosis transmembrane conductance regulator Cl- channel by two closely related arylaminobenzoates. The Journal of General Physiology. 102: 1-23. PMID 8397274  1
1993 Lester HA, Dascal N. Potassium channels. The response to vagusstoff. Nature. 364: 758-9. PMID 8355802 DOI: 10.1038/364758a0  1
1993 Dascal N, Lim NF, Schreibmayer W, Wang W, Davidson N, Lester HA. Expression of an atrial G-protein-activated potassium channel in Xenopus oocytes. Proceedings of the National Academy of Sciences of the United States of America. 90: 6596-600. PMID 8341673  1
1993 Hsu H, Huang E, Yang XC, Karschin A, Labarca C, Figl A, Ho B, Davidson N, Lester HA. Slow and incomplete inactivations of voltage-gated channels dominate encoding in synthetic neurons. Biophysical Journal. 65: 1196-206. PMID 8241400 DOI: 10.1016/S0006-3495(93)81153-6  1
1993 Mager S, Naeve J, Quick M, Labarca C, Davidson N, Lester HA. Steady states, charge movements, and rates for a cloned GABA transporter expressed in Xenopus oocytes. Neuron. 10: 177-88. PMID 7679914 DOI: 10.1016/0896-6273(93)90309-F  1
1993 Uezono Y, Bradley J, Min C, McCarty NA, Quick M, Riordan JR, Chavkin C, Zinn K, Lester HA, Davidson N. Receptors that couple to 2 classes of G proteins increase cAMP and activate CFTR expressed in Xenopus oocytes. Receptors & Channels. 1: 233-41. PMID 7522902  1
1992 Cohen BN, Labarca C, Czyzyk L, Davidson N, Lester HA. Tris+/Na+ permeability ratios of nicotinic acetylcholine receptors are reduced by mutations near the intracellular end of the M2 region. The Journal of General Physiology. 99: 545-72. PMID 1597678  1
1992 Ho BY, Karschin A, Raymond JR, Branchek T, Lester HA, Davidson N. Expression in animal cells of the 5-HT1A receptor by a vaccinia virus vector system. Febs Letters. 301: 303-6. PMID 1533596 DOI: 10.1016/0014-5793(92)80262-F  1
1992 Figl A, Cohen BN, Quick MW, Davidson N, Lester HA. Regions of beta 4.beta 2 subunit chimeras that contribute to the agonist selectivity of neuronal nicotinic receptors. Febs Letters. 308: 245-8. PMID 1505662 DOI: 10.1016/0014-5793(92)81284-S  1
1992 Cohen BN, Labarca C, Davidson N, Lester HA. Mutations in M2 alter the selectivity of the mouse nicotinic acetylcholine receptor for organic and alkali metal cations. The Journal of General Physiology. 100: 373-400. PMID 1431803  1
1992 Ho BY, Karschin A, Branchek T, Davidson N, Lester HA. The role of conserved aspartate and serine residues in ligand binding and in function of the 5-HT1A receptor: a site-directed mutation study. Febs Letters. 312: 259-62. PMID 1426261 DOI: 10.1016/0014-5793(92)80948-G  1
1992 Karschin A, Thorne BA, Thomas G, Lester HA. Vaccinia virus as vector to express ion channel genes. Methods in Enzymology. 207: 408-23. PMID 1382194  1
1992 Dascal N, Chilcott G, Lester HA. Intracellular perfusion of Xenopus oocytes. Methods in Enzymology. 207: 345-52. PMID 1382190  1
1992 Krafte DS, Lester HA. Use of stage II-III Xenopus oocytes to study voltage-dependent ion channels. Methods in Enzymology. 207: 339-45. PMID 1382189  1
1992 Charnet P, Labarca C, Lester HA. Structure of the gamma-less nicotinic acetylcholine receptor: learning from omission. Molecular Pharmacology. 41: 708-17. PMID 1373800  1
1992 Charnet P, Labarca C, Cohen BN, Davidson N, Lester HA, Pilar G. Pharmacological and kinetic properties of alpha 4 beta 2 neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes. The Journal of Physiology. 450: 375-94. PMID 1359123  1
1992 Quick MW, Naeve J, Davidson N, Lester HA. Incubation with horse serum increases viability and decreases background neurotransmitter uptake in Xenopus oocytes. Biotechniques. 13: 357-61. PMID 1356369  1
1992 Guastella J, Brecha N, Weigmann C, Lester HA, Davidson N. Cloning, expression, and localization of a rat brain high-affinity glycine transporter. Proceedings of the National Academy of Sciences of the United States of America. 89: 7189-93. PMID 1353889  1
1992 Nargeot J, Dascal N, Lester HA. Heterologous expression of calcium channels. The Journal of Membrane Biology. 126: 97-108. PMID 1317459 DOI: 10.1007/BF00231908  1
1992 Yang XC, Labarca C, Nargeot J, Ho BY, Elroy-Stein O, Moss B, Davidson N, Lester HA. Cell-specific posttranslational events affect functional expression at the plasma membrane but not tetrodotoxin sensitivity of the rat brain IIA sodium channel alpha-subunit expressed in mammalian cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 268-77. PMID 1309573  1
1991 Leonard RJ, Charnet P, Labarca C, Vogelaar NJ, Czyzyk L, Gouin A, Davidson N, Lester HA. Reverse pharmacology of the nicotinic acetylcholine receptor. Mapping the local anesthetic binding site. Annals of the New York Academy of Sciences. 625: 588-99. PMID 2058913  1
1991 Walter AE, Hoger JH, Labarca C, Yu L, Davidson N, Lester HA. Low molecular weight mRNA encodes a protein that controls serotonin 5-HT1c and acetylcholine M1 receptor sensitivity in Xenopus oocytes. The Journal of General Physiology. 98: 399-417. PMID 1940855  1
1991 Karschin A, Ho BY, Labarca C, Elroy-Stein O, Moss B, Davidson N, Lester HA. Heterologously expressed serotonin 1A receptors couple to muscarinic K+ channels in heart. Proceedings of the National Academy of Sciences of the United States of America. 88: 5694-8. PMID 1905814  1
1991 Hoger JH, Walter AE, Vance D, Yu L, Lester HA, Davidson N. Modulation of a cloned mouse brain potassium channel. Neuron. 6: 227-36. PMID 1899581 DOI: 10.1016/0896-6273(91)90358-7  1
1991 Karschin A, Aiyar J, Gouin A, Davidson N, Lester HA. K+ channel expression in primary cell cultures mediated by vaccinia virus. Febs Letters. 278: 229-33. PMID 1899389 DOI: 10.1016/0014-5793(91)80123-K  1
1991 Leonard RJ, Charnet P, Labarca C, Vogelaar NJ, Czyzyk L, Gouin A, Davidson N, Lester HA. Mutations affecting local anesthetic block of the nicotinic acetylcholine receptor ion channel. Nida Research Monograph. 111: 28-44. PMID 1723151  1
1991 Dascal N, Chilcott G, Lester HA. Recording of voltage and Ca(2+)-dependent currents in Xenopus oocytes using an intracellular perfusion method. Journal of Neuroscience Methods. 39: 29-38. PMID 1722267 DOI: 10.1016/0165-0270(91)90090-M  1
1991 Yu L, Leonard RJ, Davidson N, Lester HA. Single-channel properties of mouse-Torpedo acetylcholine receptor hybrids expressed in Xenopus oocytes. Brain Research. Molecular Brain Research. 10: 203-11. PMID 1715966 DOI: 10.1016/0169-328X(91)90062-3  1
1991 Yang XC, Karschin A, Labarca C, Elroy-Stein O, Moss B, Davidson N, Lester HA. Expression of ion channels and receptors in Xenopus oocytes using vaccinia virus. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 5: 2209-16. PMID 1708738  1
1991 Yu L, Nguyen H, Le H, Bloem LJ, Kozak CA, Hoffman BJ, Snutch TP, Lester HA, Davidson N, Lübbert H. The mouse 5-HT1C receptor contains eight hydrophobic domains and is X-linked. Brain Research. Molecular Brain Research. 11: 143-9. PMID 1661811 DOI: 10.1016/0169-328X(91)90116-F  1
1991 Hoger JH, Rudy B, Lester HA, Davidson N. Characterization of maintained voltage-dependent K(+)-channels induced in Xenopus oocytes by rat brain mRNA. Brain Research. Molecular Brain Research. 10: 1-11. PMID 1647478 DOI: 10.1016/0169-328X(91)90050-8  1
1990 Ahmed CM, Auld VJ, Lester HA, Dunn R, Davidson N. Both sodium channel II and IIA alpha subunits are expressed in rat brain. Nucleic Acids Research. 18: 5907. PMID 2170951 DOI: 10.1093/nar/18.19.5907  1
1990 Guastella J, Nelson N, Nelson H, Czyzyk L, Keynan S, Miedel MC, Davidson N, Lester HA, Kanner BI. Cloning and expression of a rat brain GABA transporter. Science (New York, N.Y.). 249: 1303-6. PMID 1975955  1
1990 Krafte DS, Goldin AL, Auld VJ, Dunn RJ, Davidson N, Lester HA. Inactivation of cloned Na channels expressed in Xenopus oocytes. The Journal of General Physiology. 96: 689-706. PMID 1701828  1
1990 Snutch TP, Leonard JP, Gilbert MM, Lester HA, Davidson N. Rat brain expresses a heterogeneous family of calcium channels. Proceedings of the National Academy of Sciences of the United States of America. 87: 3391-5. PMID 1692134  1
1990 Charnet P, Labarca C, Leonard RJ, Vogelaar NJ, Czyzyk L, Gouin A, Davidson N, Lester HA. An open-channel blocker interacts with adjacent turns of alpha-helices in the nicotinic acetylcholine receptor. Neuron. 4: 87-95. PMID 1690017 DOI: 10.1016/0896-6273(90)90445-L  1
1990 Auld VJ, Goldin AL, Krafte DS, Catterall WA, Lester HA, Davidson N, Dunn RJ. A neutral amino acid change in segment IIS4 dramatically alters the gating properties of the voltage-dependent sodium channel. Proceedings of the National Academy of Sciences of the United States of America. 87: 323-7. PMID 1688658  1
1989 Yu L, Blumer KJ, Davidson N, Lester HA, Thorner J. Functional expression of the yeast alpha-factor receptor in Xenopus oocytes. The Journal of Biological Chemistry. 264: 20847-50. PMID 2556384  1
1989 Krafte DS, Lester HA. Expression of functional sodium channels in stage II-III Xenopus oocytes. Journal of Neuroscience Methods. 26: 211-5. PMID 2537447  1
1989 Leonard RJ, Karschin A, Jayashree-Aiyar S, Davidson N, Tanouye MA, Thomas L, Thomas G, Lester HA. Expression of Drosophila Shaker potassium channels in mammalian cells infected with recombinant vaccinia virus. Proceedings of the National Academy of Sciences of the United States of America. 86: 7629-33. PMID 2477844  1
1989 Fong TM, Davidson N, Lester HA. Further evidence demonstrating that N-methyl-D-aspartate and kainate activate distinct ion channels. Synapse (New York, N.Y.). 4: 88-95. PMID 2475918 DOI: 10.1002/syn.890040110  1
1989 Lester HA, Snutch TP, Leonard JP, Nargeot J, Dascal N, Curtis BM, Davidson N. Expression of mRNA encoding voltage-dependent Ca channels in Xenopus oocytes. Review and progress report. Annals of the New York Academy of Sciences. 560: 174-82. PMID 2472764 DOI: 10.1111/j.1749-6632.1989.tb24094.x  1
1988 Rudy B, Hoger JH, Lester HA, Davidson N. At least two mRNA species contribute to the properties of rat brain A-type potassium channels expressed in Xenopus oocytes. Neuron. 1: 649-58. PMID 3272183  1
1988 Fong TM, Davidson N, Lester HA. Properties of two classes of rat brain acidic amino acid receptors induced by distinct mRNA populations in Xenopus oocytes. Synapse (New York, N.Y.). 2: 657-65. PMID 2905539 DOI: 10.1002/syn.890020613  1
1988 Auld VJ, Goldin AL, Krafte DS, Marshall J, Dunn JM, Catterall WA, Lester HA, Davidson N, Dunn RJ. A rat brain Na+ channel alpha subunit with novel gating properties. Neuron. 1: 449-61. PMID 2856097 DOI: 10.1016/0896-6273(88)90176-6  1
1988 Leonard RJ, Labarca CG, Charnet P, Davidson N, Lester HA. Evidence that the M2 membrane-spanning region lines the ion channel pore of the nicotinic receptor. Science (New York, N.Y.). 242: 1578-81. PMID 2462281  1
1988 Krafte DS, Snutch TP, Leonard JP, Davidson N, Lester HA. Evidence for the involvement of more than one mRNA species in controlling the inactivation process of rat and rabbit brain Na channels expressed in Xenopus oocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 2859-68. PMID 2457660  1
1988 Iverson LE, Tanouye MA, Lester HA, Davidson N, Rudy B. A-type potassium channels expressed from Shaker locus cDNA. Proceedings of the National Academy of Sciences of the United States of America. 85: 5723-7. PMID 2456579  1
1988 Sutton F, Davidson N, Lester HA. Tetrodotoxin-sensitive voltage-dependent Na currents recorded from Xenopus oocytes injected with mammalian cardiac muscle RNA. Brain Research. 427: 187-91. PMID 2454698 DOI: 10.1016/0169-328X(88)90065-4  1
1987 Yoshii K, Yu L, Mayne KM, Davidson N, Lester HA. Equilibrium properties of mouse-Torpedo acetylcholine receptor hybrids expressed in Xenopus oocytes. The Journal of General Physiology. 90: 553-73. PMID 3681261  1
1987 Mayne KM, Yoshii K, Yu L, Lester HA, Davidson N. Expression of mouse-Torpedo acetylcholine receptor subunit chimeras and hybrids in Xenopus oocytes. Brain Research. 388: 191-7. PMID 3676709 DOI: 10.1016/0169-328X(87)90026-X  1
1987 Lübbert H, Hoffman BJ, Snutch TP, van Dyke T, Levine AJ, Hartig PR, Lester HA, Davidson N. cDNA cloning of a serotonin 5-HT1C receptor by electrophysiological assays of mRNA-injected Xenopus oocytes. Proceedings of the National Academy of Sciences of the United States of America. 84: 4332-6. PMID 3473504 DOI: 10.1073/pnas.84.12.4332  1
1987 Lübbert H, Snutch TP, Dascal N, Lester HA, Davidson N. Rat brain 5-HT1C receptors are encoded by a 5-6 kbase mRNA size class and are functionally expressed in injected Xenopus oocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 1159-65. PMID 2883267  1
1987 Snutch TP, Leonard JP, Nargeot J, Lübbert H, Davidson N, Lester HA. Characterization of voltage-gated calcium channels in Xenopus oocytes after injection of RNA from electrically excitable tissues. Society of General Physiologists Series. 42: 153-66. PMID 2850608  1
1987 Gurney AM, Tsien RY, Lester HA. Activation of a potassium current by rapid photochemically generated step increases of intracellular calcium in rat sympathetic neurons. Proceedings of the National Academy of Sciences of the United States of America. 84: 3496-500. PMID 2437582  1
1987 Leonard JP, Nargeot J, Snutch TP, Davidson N, Lester HA. Ca channels induced in Xenopus oocytes by rat brain mRNA. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 875-81. PMID 2435866  1
1986 Dascal N, Ifune C, Hopkins R, Snutch TP, Lübbert H, Davidson N, Simon MI, Lester HA. Involvement of a GTP-binding protein in mediation of serotonin and acetylcholine responses in Xenopus oocytes injected with rat brain messenger RNA. Brain Research. 387: 201-9. PMID 2435359 DOI: 10.1016/0169-328X(86)90026-4  1
1986 Goldin AL, Snutch T, Lübbert H, Dowsett A, Marshall J, Auld V, Downey W, Fritz LC, Lester HA, Dunn R. Messenger RNA coding for only the alpha subunit of the rat brain Na channel is sufficient for expression of functional channels in Xenopus oocytes. Proceedings of the National Academy of Sciences of the United States of America. 83: 7503-7. PMID 2429308 DOI: 10.1073/pnas.83.19.7503  1
1986 Dascal N, Snutch TP, Lübbert H, Davidson N, Lester HA. Expression and modulation of voltage-gated calcium channels after RNA injection in Xenopus oocytes. Science (New York, N.Y.). 231: 1147-50. PMID 2418503  1
1985 White MM, Mayne KM, Lester HA, Davidson N. Mouse-Torpedo hybrid acetylcholine receptors: functional homology does not equal sequence homology. Proceedings of the National Academy of Sciences of the United States of America. 82: 4852-6. PMID 3860826  1
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