Loren H. Parsons - Publications

Affiliations: 
Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
neurochemistry, addiction, behavior, endocannnabinoids

114 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Moreno M, Decara J, Pavon FJ, Stouffer DG, Edwards S, Serrano A, Suárez J, Parsons LH, Rodríguez de Fonseca F. Cannabinoid dependence induces sustained changes in GABA release in the globus pallidus without affecting dopamine release in the dorsal striatum: A dual microdialysis probe study. Addiction Biology. PMID 30421559 DOI: 10.1111/adb.12694  1
2018 Pavón FJ, Serrano A, Stouffer DG, Polis I, Roberto M, Cravatt BF, Martin-Fardon R, Rodríguez de Fonseca F, Parsons LH. Ethanol-induced alterations in endocannabinoids and relevant neurotransmitters in the nucleus accumbens of fatty acid amide hydrolase knockout mice. Addiction Biology. PMID 30421483 DOI: 10.1111/adb.12695  0.8
2018 Berger AL, Henricks AM, Lugo JM, Wright HR, Warrick CR, Sticht MA, Morena M, Bonilla I, Laredo SA, Craft RM, Parsons LH, Grandes PR, Hillard CJ, Hill MN, McLaughlin RJ. The Lateral Habenula Directs Coping Styles Under Conditions of Stress Via Recruitment of the Endocannabinoid System. Biological Psychiatry. PMID 29887035 DOI: 10.1016/j.biopsych.2018.04.018  0.88
2018 Serrano A, Pavon FJ, Buczynski MW, Schlosburg J, Natividad LA, Polis IY, Stouffer DG, Zorrilla EP, Roberto M, Cravatt BF, Martin-Fardon R, Rodriguez de Fonseca F, Parsons LH. Deficient endocannabinoid signaling in the central amygdala contributes to alcohol dependence-related anxiety-like behavior and excessive alcohol intake. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29748627 DOI: 10.1038/s41386-018-0055-3  0.92
2018 Gonzalez-Cuevas G, Martin-Fardon R, Kerr TM, Stouffer DG, Parsons LH, Hammell DC, Banks SL, Stinchcomb AL, Weiss F. Unique treatment potential of cannabidiol for the prevention of relapse to drug use: preclinical proof of principle. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29686308 DOI: 10.1038/s41386-018-0050-8  1
2017 Natividad LA, Steinman MQ, Laredo SA, Irimia C, Polis IY, Lintz R, Buczynski MW, Martin-Fardon R, Roberto M, Parsons LH. Phosphorylation of calcium/calmodulin-dependent protein kinase II in the rat dorsal medial prefrontal cortex is associated with alcohol-induced cognitive inflexibility. Addiction Biology. PMID 28940879 DOI: 10.1111/adb.12568  0.92
2017 Pavon FJ, Serrano A, Sidhpura N, Polis I, Stouffer D, de Fonseca FR, Cravatt BF, Martin-Fardon R, Parsons LH. Fatty acid amide hydrolase (FAAH) inactivation confers enhanced sensitivity to nicotine-induced dopamine release in the mouse nucleus accumbens. Addiction Biology. PMID 28660730 DOI: 10.1111/adb.12531  1
2017 Natividad LA, Buczynski MW, Herman MA, Kirson D, Oleata CS, Irimia C, Polis I, Ciccocioppo R, Roberto M, Parsons LH. Constitutive Increases in Amygdalar Corticotropin-Releasing Factor and Fatty Acid Amide Hydrolase Drive an Anxious Phenotype. Biological Psychiatry. PMID 28209423 DOI: 10.1016/j.biopsych.2017.01.005  0.92
2017 Irimia C, Buczynski MW, Natividad LA, Laredo SA, Avalos N, Parsons LH. Dysregulated Glycine Signaling Contributes to Increased Impulsivity during Protracted Alcohol Abstinence. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 37: 1853-1861. PMID 28202787 DOI: 10.1523/JNEUROSCI.2466-16.2017  0.92
2016 Souza-Smith FM, Lang CH, Nagy LE, Bailey SM, Parsons LH, Murray G. APS President's Symposium Series - Physiological Processes Underlying Organ Injury in Alcohol Abuse. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00270.2016. PMID 27436613 DOI: 10.1152/ajpendo.00270.2016  0.76
2016 Nguyen JD, Aarde SM, Vandewater SA, Grant Y, Stouffer DG, Parsons LH, Cole M, Taffe MA. Inhaled delivery of Δ(9)-tetrahydrocannabinol (THC) to rats by e-cigarette vapor technology. Neuropharmacology. PMID 27256501 DOI: 10.1016/j.neuropharm.2016.05.021  0.72
2016 Buczynski MW, Herman MA, Hsu KL, Natividad LA, Irimia C, Polis IY, Pugh H, Chang JW, Niphakis MJ, Cravatt BF, Roberto M, Parsons LH. Diacylglycerol lipase disinhibits VTA dopamine neurons during chronic nicotine exposure. Proceedings of the National Academy of Sciences of the United States of America. PMID 26755579 DOI: 10.1073/pnas.1522672113  1
2015 Parsons LH, Hurd YL. Endocannabinoid signalling in reward and addiction. Nature Reviews. Neuroscience. 16: 579-94. PMID 26373473 DOI: 10.1038/nrn4004  0.76
2015 De Luca MA, Bimpisidis Z, Melis M, Marti M, Caboni P, Valentini V, Margiani G, Pintori N, Polis I, Marsicano G, Parsons LH, Di Chiara G. Stimulation of in vivo dopamine transmission and intravenous self-administration in rats and mice by JWH-018, a Spice cannabinoid. Neuropharmacology. 99: 705-714. PMID 26327678 DOI: 10.1016/j.neuropharm.2015.08.041  1
2015 Bilbao A, Serrano A, Cippitelli A, Pavón FJ, Giuffrida A, Suárez J, García-Marchena N, Baixeras E, Gómez de Heras R, Orio L, Alén F, Ciccocioppo R, Cravatt BF, Parsons LH, Piomelli D, et al. Role of the satiety factor oleoylethanolamide in alcoholism. Addiction Biology. PMID 26037332 DOI: 10.1111/adb.12276  1
2015 Herman MA, Sidhu H, Stouffer DG, Kreifeldt M, Le D, Cates-Gatto C, Munoz MB, Roberts AJ, Parsons LH, Roberto M, Wickman K, Slesinger PA, Contet C. GIRK3 gates activation of the mesolimbic dopaminergic pathway by ethanol. Proceedings of the National Academy of Sciences of the United States of America. 112: 7091-6. PMID 25964320 DOI: 10.1073/pnas.1416146112  1
2015 Varodayan FP, Soni N, Bajo M, Luu G, Madamba SG, Schweitzer P, Parsons LH, Roberto M. Chronic ethanol exposure decreases CB1 receptor function at GABAergic synapses in the rat central amygdala. Addiction Biology. PMID 25940135 DOI: 10.1111/adb.12256  1
2015 Irimia C, Polis IY, Stouffer D, Parsons LH. Persistent effects of chronic Δ9-THC exposure on motor impulsivity in rats. Psychopharmacology. PMID 25925779 DOI: 10.1007/s00213-015-3942-x  1
2015 Irimia C, Wiskerke J, Natividad LA, Polis IY, de Vries TJ, Pattij T, Parsons LH. Increased impulsivity in rats as a result of repeated cycles of alcohol intoxication and abstinence. Addiction Biology. 20: 263-74. PMID 24341858 DOI: 10.1111/adb.12119  1
2015 Talantova M, Sanz-Blasco S, Zhang X, Xia P, Akhtar MW, Okamoto SI, Dziewczapolski G, Nakamura T, Cao G, Pratt AE, Kang YJ, Tu S, Molokanova E, McKercher SR, Hires SA, ... ... Parsons LH, et al. Correction to supporting information for "Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss," Proceedings of the National Academy of Sciences of the United States of America. 112: E3751-E3752. DOI: 10.1073/pnas.1511282112  1
2015 Liu J, Parsons L, Pope C. Comparative effects of parathion and chlorpyrifos on endocannabinoid and endocannabinoid-like lipid metabolites in rat striatum Neurotoxicology. 50: 20-27. DOI: 10.1016/j.neuro.2015.07.006  1
2015 Natividad LA, Maccioni P, Parsons LH, Colombo G. Cannabinoid-alcohol interactions Cannabinoid Modulation of Emotion, Memory, and Motivation. 363-391. DOI: 10.1007/978-1-4939-2294-9_14  1
2014 Irimia C, Tuong RN, Quach T, Parsons LH. Impaired response inhibition in the rat 5 choice continuous performance task during protracted abstinence from chronic alcohol consumption. Plos One. 9: e109948. PMID 25333392 DOI: 10.1371/journal.pone.0109948  1
2014 Gonzalez-Aparicio R, Blanco E, Serrano A, Pavon FJ, Parsons LH, Maldonado R, Robledo P, Fernandez-Espejo E, de Fonseca FR. The systemic administration of oleoylethanolamide exerts neuroprotection of the nigrostriatal system in experimental Parkinsonism. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 455-68. PMID 24169105 DOI: 10.1017/S1461145713001259  1
2013 Liu J, Parsons L, Pope C. Comparative effects of parathion and chlorpyrifos on extracellular endocannabinoid levels in rat hippocampus: Influence on cholinergic toxicity Toxicology and Applied Pharmacology. 272: 608-615. PMID 23933531 DOI: 10.1016/j.taap.2013.07.025  1
2013 Talantova M, Sanz-Blasco S, Zhang X, Xia P, Akhtar MW, Okamoto S, Dziewczapolski G, Nakamura T, Cao G, Pratt AE, Kang YJ, Tu S, Molokanova E, McKercher SR, Hires SA, ... ... Parsons LH, et al. Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss. Proceedings of the National Academy of Sciences of the United States of America. 110: E2518-27. PMID 23776240 DOI: 10.1073/pnas.1306832110  1
2013 Niphakis MJ, Cognetta AB, Chang JW, Buczynski MW, Parsons LH, Byrne F, Burston JJ, Chapman V, Cravatt BF. Evaluation of NHS carbamates as a potent and selective class of endocannabinoid hydrolase inhibitors. Acs Chemical Neuroscience. 4: 1322-32. PMID 23731016 DOI: 10.1021/cn400116z  1
2013 Wright MJ, Vandewater SA, Parsons LH, Taffe MA. Δ(9)Tetrahydrocannabinol impairs reversal learning but not extra-dimensional shifts in rhesus macaques. Neuroscience. 235: 51-8. PMID 23333671 DOI: 10.1016/j.neuroscience.2013.01.018  1
2013 Buczynski MW, Polis IY, Parsons LH. The volitional nature of nicotine exposure alters anandamide and oleoylethanolamide levels in the ventral tegmental area. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 574-84. PMID 23169348 DOI: 10.1038/npp.2012.210  1
2013 Muldoon PP, Lichtman AH, Parsons LH, Damaj MI. The role of fatty acid amide hydrolase inhibition in nicotine reward and dependence. Life Sciences. 92: 458-62. PMID 22705310 DOI: 10.1016/j.lfs.2012.05.015  1
2012 Wright MJ, Angrish D, Aarde SM, Barlow DJ, Buczynski MW, Creehan KM, Vandewater SA, Parsons LH, Houseknecht KL, Dickerson TJ, Taffe MA. Effect of ambient temperature on the thermoregulatory and locomotor stimulant effects of 4-methylmethcathinone in Wistar and Sprague-Dawley rats. Plos One. 7: e44652. PMID 22952999 DOI: 10.1371/journal.pone.0044652  1
2012 Natividad LA, Buczynski MW, Parsons LH, Torres OV, O'Dell LE. Adolescent rats are resistant to adaptations in excitatory and inhibitory mechanisms that modulate mesolimbic dopamine during nicotine withdrawal. Journal of Neurochemistry. 123: 578-88. PMID 22905672 DOI: 10.1111/j.1471-4159.2012.07926.x  1
2012 Wiskerke J, Irimia C, Cravatt BF, De Vries TJ, Schoffelmeer AN, Pattij T, Parsons LH. Characterization of the effects of reuptake and hydrolysis inhibition on interstitial endocannabinoid levels in the brain: an in vivo microdialysis study. Acs Chemical Neuroscience. 3: 407-17. PMID 22860210 DOI: 10.1021/cn300036b  1
2012 Chang JW, Niphakis MJ, Lum KM, Cognetta AB, Wang C, Matthews ML, Niessen S, Buczynski MW, Parsons LH, Cravatt BF. Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates. Chemistry & Biology. 19: 579-88. PMID 22542104 DOI: 10.1016/j.chembiol.2012.03.009  1
2012 Serrano A, Rivera P, Pavon FJ, Decara J, Suárez J, Rodriguez de Fonseca F, Parsons LH. Differential effects of single versus repeated alcohol withdrawal on the expression of endocannabinoid system-related genes in the rat amygdala. Alcoholism, Clinical and Experimental Research. 36: 984-94. PMID 22141465 DOI: 10.1111/j.1530-0277.2011.01686.x  1
2011 Serrano A, Parsons LH. Endocannabinoid influence in drug reinforcement, dependence and addiction-related behaviors. Pharmacology & Therapeutics. 132: 215-41. PMID 21798285 DOI: 10.1016/j.pharmthera.2011.06.005  1
2011 Sidhpura N, Parsons LH. Endocannabinoid-mediated synaptic plasticity and addiction-related behavior. Neuropharmacology. 61: 1070-87. PMID 21669214 DOI: 10.1016/j.neuropharm.2011.05.034  1
2011 Ramchandani VA, Umhau J, Pavon FJ, Ruiz-Velasco V, Margas W, Sun H, Damadzic R, Eskay R, Schoor M, Thorsell A, Schwandt ML, Sommer WH, George DT, Parsons LH, Herscovitch P, et al. A genetic determinant of the striatal dopamine response to alcohol in men. Molecular Psychiatry. 16: 809-17. PMID 20479755 DOI: 10.1038/mp.2010.56  1
2010 Huitron-Resendiz S, Henriksen SJ, Barr MC, Testa MP, Crawford E, Parsons LH, Sanchez-Alavez M, Phillips TR. Methamphetamine and lentivirus interactions: reciprocal enhancement of central nervous system disease. Journal of Neurovirology. 16: 268-78. PMID 20608774 DOI: 10.3109/13550284.2010.497807  1
2010 Buczynski MW, Parsons LH. Quantification of brain endocannabinoid levels: methods, interpretations and pitfalls. British Journal of Pharmacology. 160: 423-42. PMID 20590555 DOI: 10.1111/j.1476-5381.2010.00787.x  1
2010 Roberto M, Cruz M, Bajo M, Siggins GR, Parsons LH, Schweitzer P. The endocannabinoid system tonically regulates inhibitory transmission and depresses the effect of ethanol in central amygdala. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1962-72. PMID 20463657 DOI: 10.1038/npp.2010.70  1
2010 Roberto M, Cruz MT, Gilpin NW, Sabino V, Schweitzer P, Bajo M, Cottone P, Madamba SG, Stouffer DG, Zorrilla EP, Koob GF, Siggins GR, Parsons LH. Corticotropin releasing factor-induced amygdala gamma-aminobutyric Acid release plays a key role in alcohol dependence. Biological Psychiatry. 67: 831-9. PMID 20060104 DOI: 10.1016/j.biopsych.2009.11.007  1
2010 Plaza-Zabala A, Berrendero F, Suarez J, Bermudez-Silva FJ, Fernandez-Espejo E, Serrano A, Pavon FJ, Parsons LH, De Fonseca FR, Maldonado R, Robledo P. Effects of the endogenous PPAR-alpha agonist, oleoylethanolamide on MDMA-induced cognitive deficits in mice. Synapse (New York, N.Y.). 64: 379-89. PMID 20029832 DOI: 10.1002/syn.20733  1
2010 Pope C, Mechoulam R, Parsons L. Endocannabinoid signaling in neurotoxicity and neuroprotection Neurotoxicology. 31: 562-571. PMID 19969019 DOI: 10.1016/j.neuro.2009.12.002  1
2009 Alvarez-Jaimes L, Polis I, Parsons LH. Regional Influence of Cannabinoid CB1 Receptors in the Regulation of Ethanol Self-Administration by Wistar Rats. The Open Neuropsychopharmacology Journal. 2: 77-85. PMID 27974944  0.56
2009 Qu Y, Saint Marie RL, Breier MR, Ko D, Stouffer D, Parsons LH, Swerdlow NR. Neural basis for a heritable phenotype: differences in the effects of apomorphine on startle gating and ventral pallidal GABA efflux in male Sprague-Dawley and Long-Evans rats. Psychopharmacology. 207: 271-80. PMID 19756524 DOI: 10.1007/s00213-009-1654-9  1
2009 Neumaier JF, McDevitt RA, Polis IY, Parsons LH. Acquisition of and withdrawal from cocaine self-administration regulates 5-HT mRNA expression in rat striatum. Journal of Neurochemistry. 111: 217-27. PMID 19659573 DOI: 10.1111/j.1471-4159.2009.06313.x  1
2009 Alvarez-Jaimes L, Stouffer DG, Parsons LH. Chronic ethanol treatment potentiates ethanol-induced increases in interstitial nucleus accumbens endocannabinoid levels in rats. Journal of Neurochemistry. 111: 37-48. PMID 19650871 DOI: 10.1111/j.1471-4159.2009.06301.x  1
2009 Abdallah L, Bonasera SJ, Hopf FW, O'Dell L, Giorgetti M, Jongsma M, Carra S, Pierucci M, Di Giovanni G, Esposito E, Parsons LH, Bonci A, Tecott LH. Impact of serotonin 2C receptor null mutation on physiology and behavior associated with nigrostriatal dopamine pathway function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8156-65. PMID 19553455 DOI: 10.1523/JNEUROSCI.3905-08.2009  1
2009 Orio L, Edwards S, George O, Parsons LH, Koob GF. A role for the endocannabinoid system in the increased motivation for cocaine in extended-access conditions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 4846-57. PMID 19369553 DOI: 10.1523/JNEUROSCI.0563-09.2009  1
2009 Villanueva A, Yilmaz SM, Millington WR, Cutrera RA, Stouffer DG, Parsons LH, Cheer JF, Feleder C. Central cannabinoid 1 receptor antagonist administration prevents endotoxic hypotension affecting norepinephrine release in the preoptic anterior hypothalamic area. Shock (Augusta, Ga.). 32: 614-20. PMID 19295473 DOI: 10.1097/SHK.0b013e3181a4fd8f  1
2009 Long JZ, Li W, Booker L, Burston JJ, Kinsey SG, Schlosburg JE, Pavón FJ, Serrano AM, Selley DE, Parsons LH, Lichtman AH, Cravatt BF. Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects. Nature Chemical Biology. 5: 37-44. PMID 19029917 DOI: 10.1038/nchembio.129  1
2009 Poceta JS, Parsons L, Engelland S, Kripke DF. Circadian rhythm of CSF monoamines and hypocretin-1 in restless legs syndrome and Parkinson's disease Sleep Medicine. 10: 129-133. PMID 18207455 DOI: 10.1016/j.sleep.2007.11.002  1
2009 Alvarez-Jaimes L, Polis I, Parsons LH. Regional influence of cannabinoid CB1 receptors in the regulation of ethanol self-administration by wistar rats Open Neuropsychopharmacology Journal. 2: 77-85. DOI: 10.2174/1876523800902020077  1
2008 Qu Y, Swerdlow NR, Weber M, Stouffer D, Parsons LH. Quinelorane, a dopamine D3/D2 receptor agonist, reduces prepulse inhibition of startle and ventral pallidal GABA efflux: time course studies. Pharmacology, Biochemistry, and Behavior. 90: 686-90. PMID 18579193 DOI: 10.1016/j.pbb.2008.05.012  1
2008 Alvarez-Jaimes L, Polis I, Parsons LH. Attenuation of cue-induced heroin-seeking behavior by cannabinoid CB1 antagonist infusions into the nucleus accumbens core and prefrontal cortex, but not basolateral amygdala. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2483-93. PMID 18059440 DOI: 10.1038/sj.npp.1301630  1
2007 George O, Ghozland S, Azar MR, Cottone P, Zorrilla EP, Parsons LH, O'Dell LE, Richardson HN, Koob GF. CRF-CRF1 system activation mediates withdrawal-induced increases in nicotine self-administration in nicotine-dependent rats. Proceedings of the National Academy of Sciences of the United States of America. 104: 17198-203. PMID 17921249 DOI: 10.1073/pnas.0707585104  1
2007 Caillé S, Alvarez-Jaimes L, Polis I, Stouffer DG, Parsons LH. Specific alterations of extracellular endocannabinoid levels in the nucleus accumbens by ethanol, heroin, and cocaine self-administration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 3695-702. PMID 17409233 DOI: 10.1523/JNEUROSCI.4403-06.2007  1
2007 Ferrer B, Bermúdez-Silva FJ, Bilbao A, Alvarez-Jaimes L, Sanchez-Vera I, Giuffrida A, Serrano A, Baixeras E, Khaturia S, Navarro M, Parsons LH, Piomelli D, Rodríguez de Fonseca F. Regulation of brain anandamide by acute administration of ethanol. The Biochemical Journal. 404: 97-104. PMID 17302558 DOI: 10.1042/BJ20061898  1
2007 Frantz KJ, O'Dell LE, Parsons LH. Behavioral and neurochemical responses to cocaine in periadolescent and adult rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 625-37. PMID 16794567 DOI: 10.1038/sj.npp.1301130  1
2007 Purdy RH, Fitzgerald RL, Everhart ET, Mellon SH, Alomary AA, Parsons LH. The analysis of neuroactive steroids by mass spectrometry Handbook of Neurochemistry and Molecular Neurobiology: Practical Neurochemistry Methods. 177-192. DOI: 10.1007/978-0-387-30401-4_7  1
2006 Guillem K, Vouillac C, Azar MR, Parsons LH, Koob GF, Cador M, Stinus L. Monoamine oxidase A rather than monoamine oxidase B inhibition increases nicotine reinforcement in rats. The European Journal of Neuroscience. 24: 3532-40. PMID 17229101 DOI: 10.1111/j.1460-9568.2006.05217.x  1
2006 O'Dell LE, Manzardo AM, Polis I, Stouffer DG, Parsons LH. Biphasic alterations in serotonin-1B (5-HT1B) receptor function during abstinence from extended cocaine self-administration. Journal of Neurochemistry. 99: 1363-76. PMID 17074068 DOI: 10.1111/j.1471-4159.2006.04163.x  1
2006 O'Dell LE, Bruijnzeel AW, Smith RT, Parsons LH, Merves ML, Goldberger BA, Richardson HN, Koob GF, Markou A. Diminished nicotine withdrawal in adolescent rats: implications for vulnerability to addiction. Psychopharmacology. 186: 612-9. PMID 16598454 DOI: 10.1007/s00213-006-0383-6  1
2006 Breese GR, Criswell HE, Carta M, Dodson PD, Hanchar HJ, Khisti RT, Mameli M, Ming Z, Morrow AL, Olsen RW, Otis TS, Parsons LH, Penland SN, Roberto M, Siggins GR, et al. Basis of the gabamimetic profile of ethanol. Alcoholism, Clinical and Experimental Research. 30: 731-44. PMID 16573592 DOI: 10.1111/j.0145-6008.2006.00086.x  1
2006 Selvage DJ, Parsons L, Rivier C. Role played by brainstem neurons in regulating testosterone secretion via a direct neural pathway between the hypothalamus and the testes. Endocrinology. 147: 3070-5. PMID 16556770 DOI: 10.1210/en.2005-1358  1
2006 Caillé S, Parsons LH. Cannabinoid modulation of opiate reinforcement through the ventral striatopallidal pathway. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 804-13. PMID 16123766 DOI: 10.1038/sj.npp.1300848  1
2005 Guillem K, Vouillac C, Azar MR, Parsons LH, Koob GF, Cador M, Stinus L. Monoamine oxidase inhibition dramatically increases the motivation to self-administer nicotine in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8593-600. PMID 16177026 DOI: 10.1523/JNEUROSCI.2139-05.2005  1
2005 Madden LJ, Flynn CT, Zandonatti MA, May M, Parsons LH, Katner SN, Henriksen SJ, Fox HS. Modeling human methamphetamine exposure in nonhuman primates: chronic dosing in the rhesus macaque leads to behavioral and physiological abnormalities. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 350-9. PMID 15483561 DOI: 10.1038/sj.npp.1300575  1
2004 Roberto M, Madamba SG, Stouffer DG, Parsons LH, Siggins GR. Increased GABA release in the central amygdala of ethanol-dependent rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10159-66. PMID 15537886 DOI: 10.1523/JNEUROSCI.3004-04.2004  1
2004 Caillé S, Parsons LH. Intravenous heroin self-administration decreases GABA efflux in the ventral pallidum: an in vivo microdialysis study in rats. The European Journal of Neuroscience. 20: 593-6. PMID 15233770 DOI: 10.1111/j.1460-9568.2004.03497.x  1
2004 O'Dell LE, Parsons LH. Serotonin1B receptors in the ventral tegmental area modulate cocaine-induced increases in nucleus accumbens dopamine levels. The Journal of Pharmacology and Experimental Therapeutics. 311: 711-9. PMID 15226384 DOI: 10.1124/jpet.104.069278  1
2004 Koob GF, Ahmed SH, Boutrel B, Chen SA, Kenny PJ, Markou A, O'Dell LE, Parsons LH, Sanna PP. Neurobiological mechanisms in the transition from drug use to drug dependence. Neuroscience and Biobehavioral Reviews. 27: 739-49. PMID 15019424 DOI: 10.1016/j.neubiorev.2003.11.007  1
2004 Roberto M, Schweitzer P, Madamba SG, Stouffer DG, Parsons LH, Siggins GR. Acute and chronic ethanol alter glutamatergic transmission in rat central amygdala: an in vitro and in vivo analysis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 1594-603. PMID 14973247 DOI: 10.1523/JNEUROSCI.5077-03.2004  1
2004 Selvage DJ, Lee SY, Parsons LH, Seo DO, Rivier CL. A hypothalamic-testicular neural pathway is influenced by brain catecholamines, but not testicular blood flow. Endocrinology. 145: 1750-9. PMID 14684600 DOI: 10.1210/en.2003-1441  1
2003 Caillé S, Parsons LH. SR141716A reduces the reinforcing properties of heroin but not heroin-induced increases in nucleus accumbens dopamine in rats. The European Journal of Neuroscience. 18: 3145-9. PMID 14656311 DOI: 10.1111/j.1460-9568.2003.02961.x  1
2003 Taffe MA, Huitrón-Resendiz S, Schroeder R, Parsons LH, Henriksen SJ, Gold LH. MDMA exposure alters cognitive and electrophysiological sensitivity to rapid tryptophan depletion in rhesus monkeys. Pharmacology, Biochemistry, and Behavior. 76: 141-52. PMID 13679227 DOI: 10.1016/S0091-3057(03)00217-X  1
2003 Ahmed SH, Lin D, Koob GF, Parsons LH. Escalation of cocaine self-administration does not depend on altered cocaine-induced nucleus accumbens dopamine levels. Journal of Neurochemistry. 86: 102-13. PMID 12807430 DOI: 10.1046/j.1471-4159.2003.01833.x  1
2002 Taffe MA, Davis SA, Yuan J, Schroeder R, Hatzidimitriou G, Parsons LH, Ricaurte GA, Gold LH. Cognitive performance of MDMA-treated rhesus monkeys: sensitivity to serotonergic challenge. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 27: 993-1005. PMID 12464456 DOI: 10.1016/S0893-133X(02)00380-9  1
2002 Rocha BA, Goulding EH, O'Dell LE, Mead AN, Coufal NG, Parsons LH, Tecott LH. Enhanced locomotor, reinforcing, and neurochemical effects of cocaine in serotonin 5-hydroxytryptamine 2C receptor mutant mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10039-45. PMID 12427861  1
2002 Hungund BL, Basavarajappa BS, Vadasz C, Kunos G, Rodriguez de Fonseca F, Colombo G, Serra S, Parsons L, Koob GF. Ethanol, endocannabinoids, and the cannabinoidergic signaling system. Alcoholism, Clinical and Experimental Research. 26: 565-74. PMID 11981134  1
2002 Lin D, Parsons LH. Anxiogenic-like effect of serotonin(1B) receptor stimulation in the rat elevated plus-maze. Pharmacology, Biochemistry, and Behavior. 71: 581-7. PMID 11888549 DOI: 10.1016/S0091-3057(01)00712-2  1
2002 Frantz KJ, Hansson KJ, Stouffer DG, Parsons LH. 5-HT(6) receptor antagonism potentiates the behavioral and neurochemical effects of amphetamine but not cocaine. Neuropharmacology. 42: 170-80. PMID 11804613 DOI: 10.1016/S0028-3908(01)00165-4  1
2001 Weiss F, Ciccocioppo R, Parsons LH, Katner S, Liu X, Zorrilla EP, Valdez GR, Ben-Shahar O, Angeletti S, Richter RR. Compulsive drug-seeking behavior and relapse. Neuroadaptation, stress, and conditioning factors. Annals of the New York Academy of Sciences. 937: 1-26. PMID 11458532  1
2001 Parsons LH, Kerr TM, Tecott LH. 5-HT(1A) receptor mutant mice exhibit enhanced tonic, stress-induced and fluoxetine-induced serotonergic neurotransmission. Journal of Neurochemistry. 77: 607-17. PMID 11299323 DOI: 10.1046/j.1471-4159.2001.00254.x  1
2001 Taffe MA, Weed MR, Davis S, Huitrón-Resendiz S, Schroeder R, Parsons LH, Henriksen SJ, Gold LH. Functional consequences of repeated (+/-)3,4-methylenedioxymethamphetamine (MDMA) treatment in rhesus monkeys. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 24: 230-9. PMID 11166514 DOI: 10.1016/S0893-133X(00)00185-8  1
2000 Solbrig MV, Koob GF, Parsons LH, Kadota T, Horscroft N, Briese T, Lipkin WI. Neurotrophic factor expression after CNS viral injury produces enhanced sensitivity to psychostimulants: potential mechanism for addiction vulnerability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: RC104. PMID 11050146  1
2000 Weiss F, Maldonado-Vlaar CS, Parsons LH, Kerr TM, Smith DL, Ben-Shahar O. Control of cocaine-seeking behavior by drug-associated stimuli in rats: effects on recovery of extinguished operant-responding and extracellular dopamine levels in amygdala and nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. 97: 4321-6. PMID 10760299 DOI: 10.1073/pnas.97.8.4321  1
1999 Parsons LH, Koob GF, Weiss F. RU 24969, a 5-HT1B/1A receptor agonist, potentiates cocaine-induced increases in nucleus accumbens dopamine. Synapse (New York, N.Y.). 32: 132-5. PMID 10231132 DOI: 10.1002/(SICI)1098-2396(199905)32:2<132::AID-SYN6>3.0.CO;2-V  1
1999 Giuffrida A, Parsons LH, Kerr TM, Rodríguez de Fonseca F, Navarro M, Piomelli D. Dopamine activation of endogenous cannabinoid signaling in dorsal striatum. Nature Neuroscience. 2: 358-63. PMID 10204543 DOI: 10.1038/7268  1
1999 Harrison AA, Parsons LH, Koob GF, Markou A. RU 24969, a 5-HT1A/1B agonist, elevates brain stimulation reward thresholds: an effect reversed by GR 127935, a 5-HT1B/1D antagonist. Psychopharmacology. 141: 242-50. PMID 10027505 DOI: 10.1007/s002130050831  1
1998 Heisler LK, Chu HM, Brennan TJ, Danao JA, Bajwa P, Parsons LH, Tecott LH. Elevated anxiety and antidepressant-like responses in serotonin 5-HT1A receptor mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 95: 15049-54. PMID 9844013 DOI: 10.1073/pnas.95.25.15049  1
1998 Parsons LH, Weiss F, Koob GF. Serotonin1B receptor stimulation enhances cocaine reinforcement. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 10078-89. PMID 9822762  1
1998 Parsons LH, Kerr TM, Weiss F. Simple microbore high-performance liquid chromatographic method for the determination of dopamine and cocaine from a single in vivo brain microdialysis sample. Journal of Chromatography. B, Biomedical Sciences and Applications. 709: 35-45. PMID 9653924 DOI: 10.1016/S0378-4347(98)00024-3  1
1998 Koob GF, Rocio M, Carrera A, Gold LH, Heyser CJ, Maldonado-Irizarry C, Markou A, Parsons LH, Roberts AJ, Schulteis G, Stinus L, Walker JR, Weissenborn R, Weiss F. Substance dependence as a compulsive behavior. Journal of Psychopharmacology (Oxford, England). 12: 39-48. PMID 9584967 DOI: 10.1177/026988119801200106  1
1998 Koob GF, Roberts AJ, Schulteis G, Parsons LH, Heyser CJ, Hyytiä P, Merlo-Pich E, Weiss F. Neurocircuitry targets in ethanol reward and dependence. Alcoholism, Clinical and Experimental Research. 22: 3-9. PMID 9514280  1
1997 Caine SB, Koob GF, Parsons LH, Everitt BJ, Schwartz JC, Sokoloff P. D3 receptor test in vitro predicts decreased cocaine self-administration in rats. Neuroreport. 8: 2373-7. PMID 9243643  1
1997 Koob GF, Caine SB, Parsons L, Markou A, Weiss F. Opponent process model and psychostimulant addiction. Pharmacology, Biochemistry, and Behavior. 57: 513-21. PMID 9218276 DOI: 10.1016/S0091-3057(96)00438-8  1
1997 Raber J, Mehta PP, Kreifeldt M, Parsons LH, Weiss F, Bloom FE, Wilson MC. Coloboma hyperactive mutant mice exhibit regional and transmitter-specific deficits in neurotransmission. Journal of Neurochemistry. 68: 176-86. PMID 8978724  1
1996 Parsons LH, Weiss F, Koob GF. Serotonin1b receptor stimulation enhances dopamine-mediated reinforcement. Psychopharmacology. 128: 150-60. PMID 8956376 DOI: 10.1007/s002130050120  1
1996 Parsons LH, Koob GF, Weiss F. Extracellular serotonin is decreased in the nucleus accumbens during withdrawal from cocaine self-administration. Behavioural Brain Research. 73: 225-8. PMID 8788507 DOI: 10.1016/0166-4328(96)00101-5  1
1996 Parsons LH, Caine SB, Sokoloff P, Schwartz JC, Koob GF, Weiss F. Neurochemical evidence that postsynaptic nucleus accumbens D3 receptor stimulation enhances cocaine reinforcement. Journal of Neurochemistry. 67: 1078-89. PMID 8752115  1
1996 Weiss F, Parsons LH, Schulteis G, Hyytiä P, Lorang MT, Bloom FE, Koob GF. Ethanol self-administration restores withdrawal-associated deficiencies in accumbal dopamine and 5-hydroxytryptamine release in dependent rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 3474-85. PMID 8627380  1
1995 Parsons LH, Koob GF, Weiss F. Serotonin dysfunction in the nucleus accumbens of rats during withdrawal after unlimited access to intravenous cocaine. The Journal of Pharmacology and Experimental Therapeutics. 274: 1182-91. PMID 7562486  1
1995 Carrera MR, Ashley JA, Parsons LH, Wirsching P, Koob GF, Janda KD. Suppression of psychoactive effects of cocaine by active immunization. Nature. 378: 727-30. PMID 7501020 DOI: 10.1038/378727a0  1
1994 Parsons LH, Justice JB. Quantitative approaches to in vivo brain microdialysis. Critical Reviews in Neurobiology. 8: 189-220. PMID 7923396  1
1994 Cosford RJ, Parsons LH, Justice JB. Effect of tetrodotoxin and potassium infusion on microdialysis extraction fraction and extracellular dopamine in the nucleus accumbens. Neuroscience Letters. 178: 175-8. PMID 7824191 DOI: 10.1016/0304-3940(94)90753-6  1
1993 Parsons LH, Justice JB. Perfusate serotonin increases extracellular dopamine in the nucleus accumbens as measured by in vivo microdialysis. Brain Research. 606: 195-9. PMID 8490716 DOI: 10.1016/0006-8993(93)90984-U  1
1993 Parsons LH, Schad CA, Justice JB. Co-administration of the D2 antagonist pimozide inhibits up-regulation of dopamine release and uptake induced by repeated cocaine. Journal of Neurochemistry. 60: 376-9. PMID 8417161  1
1993 Parsons LH, Justice JB. Serotonin and dopamine sensitization in the nucleus accumbens, ventral tegmental area, and dorsal raphe nucleus following repeated cocaine administration. Journal of Neurochemistry. 61: 1611-9. PMID 7693863 DOI: 10.1111/j.1471-4159.1993.tb09794.x  1
1992 Parsons LH, Justice JB. Extracellular concentration and in vivo recovery of dopamine in the nucleus accumbens using microdialysis. Journal of Neurochemistry. 58: 212-8. PMID 1727431  1
1991 Parsons LH, Smith AD, Justice JB. The in vivo microdialysis recovery of dopamine is altered independently of basal level by 6-hydroxydopamine lesions to the nucleus accumbens. Journal of Neuroscience Methods. 40: 139-47. PMID 1800851 DOI: 10.1016/0165-0270(91)90063-6  1
1991 Parsons LH, Smith AD, Justice JB. Basal extracellular dopamine is decreased in the rat nucleus accumbens during abstinence from chronic cocaine. Synapse (New York, N.Y.). 9: 60-5. PMID 1796352 DOI: 10.1002/syn.890090109  1
1990 Pettit HO, Pan HT, Parsons LH, Justice JB. Extracellular concentrations of cocaine and dopamine are enhanced during chronic cocaine administration. Journal of Neurochemistry. 55: 798-804. PMID 2384752 DOI: 10.1111/j.1471-4159.1990.tb04562.x  1
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