Richard M. Van Rijn, Ph.D. - Publications

2013- Medicinal Chemistry and Molecular Pharmacology Purdue University, West Lafayette, IN, United States 
opioid receptors, addiction, alcoholism

40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Creed SM, Gutridge AM, Argade MD, Hennessy MR, Friesen JB, Pauli GF, van Rijn RM, Riley AP. Isolation and Pharmacological Characterization of Six Opioidergic Alkaloids. Journal of Natural Products. PMID 33326237 DOI: 10.1021/acs.jnatprod.0c01036  0.64
2019 Cassell RJ, Sharma KK, Su H, Cummins BR, Cui H, Mores KL, Blaine AT, Altman RA, van Rijn RM. The Meta-Position of Phe in Leu-Enkephalin Regulates Potency, Selectivity, Functional Activity, and Signaling Bias at the Delta and Mu Opioid Receptors. Molecules (Basel, Switzerland). 24. PMID 31842282 DOI: 10.3390/Molecules24244542  1
2019 Gutridge AM, Robins MT, Cassell RJ, Uprety R, Mores KL, Ko MJ, Pasternak GW, Majumdar S, van Rijn RM. G protein-biased kratom-alkaloids and synthetic carfentanil-amide opioids as potential treatments for alcohol use disorder. British Journal of Pharmacology. PMID 31705528 DOI: 10.1111/Bph.14913  1
2019 Ko MJ, van Rijn RM. Response: Commentary: Commonly Used Anesthesia/Euthanasia Methods for Brain Collection Differentially Impact MAPK Activity in Male and Female C57BL/6 Mice. Frontiers in Cellular Neuroscience. 13: 379. PMID 31474837 DOI: 10.3389/fncel.2019.00379  1
2019 Mores KL, Cummins BR, Cassell RJ, van Rijn RM. A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists. Frontiers in Pharmacology. 10: 407. PMID 31057409 DOI: 10.3389/fphar.2019.00407  1
2019 Ko MJ, Mulia GE, van Rijn RM. Commonly Used Anesthesia/Euthanasia Methods for Brain Collection Differentially Impact MAPK Activity in Male and Female C57BL/6 Mice. Frontiers in Cellular Neuroscience. 13: 96. PMID 30983972 DOI: 10.3389/fncel.2019.00096  1
2019 Robins MT, Blaine AT, Ha JE, Brewster AL, van Rijn RM. Repeated Use of the Psychoactive Substance Ethylphenidate Impacts Neurochemistry and Reward Learning in Adolescent Male and Female Mice. Frontiers in Neuroscience. 13: 124. PMID 30837836 DOI: 10.3389/Fnins.2019.00124  1
2019 Ko MJ, Ganzen LC, Coskun E, Mukadam AA, Leung YF, van Rijn RM. A critical evaluation of TRPA1-mediated locomotor behavior in zebrafish as a screening tool for novel anti-nociceptive drug discovery. Scientific Reports. 9: 2430. PMID 30787340 DOI: 10.1038/S41598-019-38852-9  1
2018 Cassell RJ, Mores KL, Zerfas BL, Mahmoud AH, Lill MA, Trader DJ, van Rijn RM. Rubiscolins are naturally occurring G protein-biased delta opioid receptor peptides. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 30591345 DOI: 10.1016/J.Euroneuro.2018.12.013  1
2018 Kaur J, Soto-Velasquez M, Ding Z, Ghanbarpour A, Lill MA, van Rijn RM, Watts VJ, Flaherty DP. Optimization of a 1,3,4-oxadiazole series for inhibition of Ca/calmodulin-stimulated activity of adenylyl cyclases 1 and 8 for the treatment of chronic pain. European Journal of Medicinal Chemistry. 162: 568-585. PMID 30472604 DOI: 10.1016/J.Ejmech.2018.11.036  0.4
2018 Robins MT, Chiang T, Mores KL, Alongkronrusmee D, van Rijn RM. Critical Role for G-Protein Activity in the Dorsal Striatum in the Reduction of Voluntary Alcohol Intake in C57Bl/6 Mice. Frontiers in Psychiatry. 9: 112. PMID 29686629 DOI: 10.3389/Fpsyt.2018.00112  1
2018 Robins MT, Chiang T, Berry JN, Ko MJ, Ha JE, van Rijn RM. Behavioral Characterization of β-Arrestin 1 Knockout Mice in Anxiety-Like and Alcohol Behaviors. Frontiers in Behavioral Neuroscience. 12: 54. PMID 29615880 DOI: 10.3389/Fnbeh.2018.00054  1
2017 Márquez-Gómez R, Robins MT, Gutiérrez-Rodelo C, Arias JM, Olivares-Reyes JA, van Rijn RM, Arias-Montaño JA. Functional histamine H3 and adenosine A2A receptor heteromers in recombinant cells and rat striatum. Pharmacological Research. PMID 29217157 DOI: 10.1016/J.Phrs.2017.11.036  1
2017 Brust TF, Alongkronrusmee D, Soto-Velasquez M, Baldwin TA, Ye Z, Dai M, Dessauer CW, van Rijn RM, Watts VJ. Identification of a selective small-molecule inhibitor of type 1 adenylyl cyclase activity with analgesic properties. Science Signaling. 10. PMID 28223412 DOI: 10.1126/Scisignal.Aah5381  1
2017 Zeng L, Alongkronrusmee D, van Rijn RM. An integrated perspective on diabetic, alcoholic, and drug-induced neuropathy, etiology, and treatment in the US. Journal of Pain Research. 10: 219-228. PMID 28176937 DOI: 10.2147/Jpr.S125987  1
2016 Alongkronrusmee D, Chiang T, van Rijn RM. Involvement of delta opioid receptors in alcohol withdrawal-induced mechanical allodynia in male C57BL/6 mice. Drug and Alcohol Dependence. PMID 27567436 DOI: 10.1016/J.Drugalcdep.2016.08.017  1
2016 Robins MT, DeFriel JN, van Rijn RM. Adolescent intake of caffeinated energy drinks does not affect adult alcohol consumption in C57BL/6 and BALB/c mice. Alcohol (Fayetteville, N.Y.). 54: 1-9. PMID 27565749 DOI: 10.1016/J.Alcohol.2016.05.001  1
2016 Yang S, Ben-Shalom R, Ahn M, Liptak AT, van Rijn RM, Whistler JL, Bender KJ. β-Arrestin-Dependent Dopaminergic Regulation of Calcium Channel Activity in the Axon Initial Segment. Cell Reports. PMID 27452469 DOI: 10.1016/J.Celrep.2016.06.098  1
2016 Robins MT, Lu J, van Rijn RM. Unique Behavioral and Neurochemical Effects Induced by Repeated Adolescent Consumption of Caffeine-Mixed Alcohol in C57BL/6 Mice. Plos One. 11: e0158189. PMID 27380261 DOI: 10.1371/Journal.Pone.0158189  1
2016 Alongkronrusmee D, Chiang T, van Rijn RM. Delta Opioid Pharmacology in Relation to Alcohol Behaviors. Handbook of Experimental Pharmacology. PMID 27316912 DOI: 10.1007/164_2016_30  1
2015 Chiang T, Sansuk K, van Rijn RM. Beta-arrestin 2 dependence of delta opioid receptor agonists is correlated with alcohol intake. British Journal of Pharmacology. PMID 26507558 DOI: 10.1111/Bph.13374  1
2013 van Rijn RM, Defriel JN, Whistler JL. Pharmacological traits of delta opioid receptors: pitfalls or opportunities? Psychopharmacology. 228: 1-18. PMID 23649885 DOI: 10.1007/S00213-013-3129-2  1
2013 Milan-Lobo L, Enquist J, van Rijn RM, Whistler JL. Anti-analgesic effect of the mu/delta opioid receptor heteromer revealed by ligand-biased antagonism. Plos One. 8: e58362. PMID 23554887 DOI: 10.1371/Journal.Pone.0058362  1
2013 Harvey JH, van Rijn RM, Whistler JL. A FLIPR assay for evaluating agonists and antagonists of GPCR heterodimers. Methods in Molecular Biology (Clifton, N.J.). 995: 43-54. PMID 23494371 DOI: 10.1007/978-1-62703-345-9_4  1
2013 van Rijn RM, Harvey JH, Brissett DI, DeFriel JN, Whistler JL. Novel screening assay for the selective detection of G-protein-coupled receptor heteromer signaling. The Journal of Pharmacology and Experimental Therapeutics. 344: 179-88. PMID 23097213 DOI: 10.1124/Jpet.112.198655  1
2012 Brissett DI, Whistler JL, van Rijn RM. Contribution of mu and delta opioid receptors to the pharmacological profile of kappa opioid receptor subtypes. European Journal of Pain (London, England). 16: 327-37. PMID 22337177 DOI: 10.1002/J.1532-2149.2011.00022.X  1
2012 van Rijn RM, Brissett DI, Whistler JL. Distinctive modulation of ethanol place preference by delta opioid receptor-selective agonists. Drug and Alcohol Dependence. 122: 156-9. PMID 22018601 DOI: 10.1016/J.Drugalcdep.2011.09.024  1
2012 van Rijn RM, Brissett DI, Whistler JL. Emergence of functional spinal delta opioid receptors after chronic ethanol exposure. Biological Psychiatry. 71: 232-8. PMID 21889123 DOI: 10.1016/J.Biopsych.2011.07.015  1
2010 van Rijn RM, Brissett DI, Whistler JL. Dual efficacy of delta opioid receptor-selective ligands for ethanol drinking and anxiety. The Journal of Pharmacology and Experimental Therapeutics. 335: 133-9. PMID 20605909 DOI: 10.1124/Jpet.110.170969  1
2010 van Rijn RM, Rhee IK, Verpoorte R. Isolation of acetylcholinesterase inhibitory alkaloids from Nerine bowdenii. Natural Product Research. 24: 222-5. PMID 20140801 DOI: 10.1080/14786410802263758  1
2010 van Rijn RM, Whistler JL, Waldhoer M. Opioid-receptor-heteromer-specific trafficking and pharmacology. Current Opinion in Pharmacology. 10: 73-9. PMID 19846340 DOI: 10.1016/J.Coph.2009.09.007  1
2009 van Rijn RM, Whistler JL. The delta(1) opioid receptor is a heterodimer that opposes the actions of the delta(2) receptor on alcohol intake. Biological Psychiatry. 66: 777-84. PMID 19576572 DOI: 10.1016/J.Biopsych.2009.05.019  1
2009 He L, Kim J, Ou C, McFadden W, van Rijn RM, Whistler JL. Methadone antinociception is dependent on peripheral opioid receptors. The Journal of Pain : Official Journal of the American Pain Society. 10: 369-79. PMID 19327642 DOI: 10.1016/J.Jpain.2008.09.011  1
2008 van Rijn RM, Whistler JL. The only way is up: preventing opioid tolerance by promoting cell surface expression of MOR-DOR heterodimers? Molecular Interventions. 8: 277-80. PMID 19144899 DOI: 10.1124/Mi.8.6.4  1
2008 van Rijn RM, van Marle A, Chazot PL, Langemeijer E, Qin Y, Shenton FC, Lim HD, Zuiderveld OP, Sansuk K, Dy M, Smit MJ, Tensen CP, Bakker RA, Leurs R. Cloning and characterization of dominant negative splice variants of the human histamine H4 receptor. The Biochemical Journal. 414: 121-31. PMID 18452403 DOI: 10.1042/Bj20071583  1
2006 van Rijn RM, Chazot PL, Shenton FC, Sansuk K, Bakker RA, Leurs R. Oligomerization of recombinant and endogenously expressed human histamine H(4) receptors. Molecular Pharmacology. 70: 604-15. PMID 16645125 DOI: 10.1124/Mol.105.020818  1
2006 Bakker RA, Lozada AF, van Marle A, Shenton FC, Drutel G, Karlstedt K, Hoffmann M, Lintunen M, Yamamoto Y, van Rijn RM, Chazot PL, Panula P, Leurs R. Discovery of naturally occurring splice variants of the rat histamine H3 receptor that act as dominant-negative isoforms. Molecular Pharmacology. 69: 1194-206. PMID 16415177 DOI: 10.1124/Mol.105.019299  1
2005 Lim HD, van Rijn RM, Ling P, Bakker RA, Thurmond RL, Leurs R. Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist. The Journal of Pharmacology and Experimental Therapeutics. 314: 1310-21. PMID 15947036 DOI: 10.1124/jpet.105.087965  1
2004 Terzioglu N, van Rijn RM, Bakker RA, De Esch IJ, Leurs R. Synthesis and structure-activity relationships of indole and benzimidazole piperazines as histamine H(4) receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 14: 5251-6. PMID 15454206 DOI: 10.1016/j.bmcl.2004.08.035  1
2003 Rhee IK, van Rijn RM, Verpoorte R. Qualitative determination of false-positive effects in the acetylcholinesterase assay using thin layer chromatography. Phytochemical Analysis : Pca. 14: 127-31. PMID 12793457 DOI: 10.1002/Pca.675  1
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