Mary Kay Lobo, PhD - Publications

Affiliations: 
2011- Anatomy and Neurobiology University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Molecular and Circuit Mechanisms of Motivational Diseases
Website:
lobolab.org

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Fox ME, Lobo MK. The molecular and cellular mechanisms of depression: a focus on reward circuitry. Molecular Psychiatry. PMID 30967681 DOI: 10.1038/s41380-019-0415-3  0.92
2019 Francis TC, Gaynor A, Chandra R, Fox ME, Lobo MK. The Selective RhoA Inhibitor Rhosin Promotes Stress Resiliency Through Enhancing D1-Medium Spiny Neuron Plasticity and Reducing Hyperexcitability. Biological Psychiatry. PMID 30955841 DOI: 10.1016/j.biopsych.2019.02.007  0.92
2019 Iñiguez SD, Parise LF, Lobo MK, Flores-Ramirez FJ, Garcia-Carachure I, Warren BL, Robison AJ. Upregulation of hippocampal extracellular signal-regulated kinase (ERK)-2 induces antidepressant-like behavior in the rat forced swim test. Behavioral Neuroscience. 133: 225-231. PMID 30907619 DOI: 10.1037/bne0000303  0.64
2018 LeGates TA, Kvarta MD, Tooley JR, Francis TC, Lobo MK, Creed MC, Thompson SM. Reward behaviour is regulated by the strength of hippocampus-nucleus accumbens synapses. Nature. PMID 30478293 DOI: 10.1038/s41586-018-0740-8  0.84
2018 Divakaruni SS, Van Dyke AM, Chandra R, LeGates TA, Contreras M, Dharmasri PA, Higgs HN, Lobo MK, Thompson SM, Blanpied TA. Long-Term Potentiation Requires a Rapid Burst of Dendritic Mitochondrial Fission during Induction. Neuron. PMID 30318410 DOI: 10.1016/j.neuron.2018.09.025  0.6
2018 Fox ME, Chandra R, Menken MS, Larkin EJ, Nam H, Engeln M, Francis TC, Lobo MK. Dendritic remodeling of D1 neurons by RhoA/Rho-kinase mediates depression-like behavior. Molecular Psychiatry. PMID 30120419 DOI: 10.1038/s41380-018-0211-5  0.92
2018 Engeln M, Fox ME, Lobo MK. Dopamine Is Differentially Encoded by D2 Receptors in Striatal Subregions. Neuron. 98: 459-461. PMID 29723497 DOI: 10.1016/j.neuron.2018.04.016  0.92
2018 Heshmati M, Aleyasin H, Menard C, Christoffel DJ, Flanigan ME, Pfau ML, Hodes GE, Lepack AE, Bicks LK, Takahashi A, Chandra R, Turecki G, Lobo MK, Maze I, Golden SA, et al. Cell-type-specific role for nucleus accumbens neuroligin-2 in depression and stress susceptibility. Proceedings of the National Academy of Sciences of the United States of America. PMID 29339486 DOI: 10.1073/pnas.1719014115  0.6
2017 Chandra R, Engeln M, Schiefer C, Patton MH, Martin JA, Werner CT, Riggs LM, Francis TC, McGlincy M, Evans B, Nam H, Das S, Girven K, Konkalmatt P, Gancarz AM, ... ... Lobo MK, et al. Drp1 Mitochondrial Fission in D1 Neurons Mediates Behavioral and Cellular Plasticity during Early Cocaine Abstinence. Neuron. 96: 1327-1341.e6. PMID 29268097 DOI: 10.1016/j.neuron.2017.11.037  0.92
2017 Chandra R, Lobo MK. Beyond Neuronal Activity Markers: Select Immediate Early Genes in Striatal Neuron Subtypes Functionally Mediate Psychostimulant Addiction. Frontiers in Behavioral Neuroscience. 11: 112. PMID 28642692 DOI: 10.3389/fnbeh.2017.00112  0.6
2017 Castro A, Li Y, Raver C, Chandra R, Masri R, Lobo MK, Keller A. Neuropathic pain after chronic nerve constriction may not correlate with chloride dysregulation in mouse trigeminal nucleus caudalis neurons. Pain. PMID 28426550 DOI: 10.1097/j.pain.0000000000000926  0.6
2017 Terrillion CE, Francis TC, Puche AC, Lobo MK, Gould TD. Decreased nucleus accumbens expression of psychiatric disorder risk gene Cacna1c promotes susceptibility to social stress. The International Journal of Neuropsychopharmacology. PMID 28165117 DOI: 10.1093/ijnp/pyw112  0.84
2016 Chandra R, Engeln M, Francis TC, Konkalmatt P, Patel D, Lobo MK. A Role for Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1α in Nucleus Accumbens Neuron Subtypes in Cocaine Action. Biological Psychiatry. PMID 27939396 DOI: 10.1016/j.biopsych.2016.10.024  0.92
2016 Francis TC, Lobo MK. Emerging Role for Nucleus Accumbens Medium Spiny Neuron Subtypes in Depression. Biological Psychiatry. PMID 27871668 DOI: 10.1016/j.biopsych.2016.09.007  0.84
2016 Creed M, Ntamati NR, Chandra R, Lobo MK, Lüscher C. Convergence of Reinforcing and Anhedonic Cocaine Effects in the Ventral Pallidum. Neuron. PMID 27667004 DOI: 10.1016/j.neuron.2016.09.001  0.6
2016 Damez-Werno DM, Sun H, Scobie KN, Shao N, Rabkin J, Dias C, Calipari ES, Maze I, Pena CJ, Walker DM, Cahill ME, Chandra R, Gancarz A, Mouzon E, Landry JA, ... ... Lobo MK, et al. Histone arginine methylation in cocaine action in the nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. PMID 27506785 DOI: 10.1073/pnas.1605045113  1
2015 Kupchik YM, Brown RM, Heinsbroek JA, Lobo MK, Schwartz DJ, Kalivas PW. Coding the direct/indirect pathways by D1 and D2 receptors is not valid for accumbens projections. Nature Neuroscience. PMID 26214370 DOI: 10.1038/nn.4068  1
2015 Wright KN, Hollis F, Duclot F, Dossat AM, Strong CE, Francis TC, Mercer R, Feng J, Dietz DM, Lobo MK, Nestler EJ, Kabbaj M. Methyl Supplementation Attenuates Cocaine-Seeking Behaviors and Cocaine-Induced c-Fos Activation in a DNA Methylation-Dependent Manner. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8948-58. PMID 26063926 DOI: 10.1523/JNEUROSCI.5227-14.2015  1
2015 Chandra R, Francis TC, Konkalmatt P, Amgalan A, Gancarz AM, Dietz DM, Lobo MK. Opposing role for egr3 in nucleus accumbens cell subtypes in cocaine action. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 7927-37. PMID 25995477 DOI: 10.1523/JNEUROSCI.0548-15.2015  1
2015 Ilango A, Lobo MK. Shining light on motivation, emotion, and memory processes. Frontiers in Behavioral Neuroscience. 9: 1. PMID 25653603 DOI: 10.3389/fnbeh.2015.00001  1
2015 Koo JW, Mazei-Robison MS, LaPlant Q, Egervari G, Braunscheidel KM, Adank DN, Ferguson D, Feng J, Sun H, Scobie KN, Damez-Werno DM, Ribeiro E, Peña CJ, Walker D, Bagot RC, ... ... Lobo MK, et al. Epigenetic basis of opiate suppression of Bdnf gene expression in the ventral tegmental area. Nature Neuroscience. 18: 415-22. PMID 25643298 DOI: 10.1038/nn.3932  1
2015 Francis TC, Chandra R, Friend DM, Finkel E, Dayrit G, Miranda J, Brooks JM, Iñiguez SD, O'Donnell P, Kravitz A, Lobo MK. Nucleus accumbens medium spiny neuron subtypes mediate depression-related outcomes to social defeat stress. Biological Psychiatry. 77: 212-22. PMID 25173629 DOI: 10.1016/j.biopsych.2014.07.021  1
2015 Francis TC, Lobo MK. Optogenetic regulation of dopamine receptor-expressing neurons Neuromethods. 96: 329-342. DOI: 10.1007/978-1-4939-2196-6_18  1
2014 Zhang Y, Crofton EJ, Li D, Lobo MK, Fan X, Nestler EJ, Green TA. Overexpression of DeltaFosB in nucleus accumbens mimics the protective addiction phenotype, but not the protective depression phenotype of environmental enrichment. Frontiers in Behavioral Neuroscience. 8: 297. PMID 25221490 DOI: 10.3389/fnbeh.2014.00297  1
2014 Koo JW, Lobo MK, Chaudhury D, Labonté B, Friedman A, Heller E, Peña CJ, Han MH, Nestler EJ. Loss of BDNF signaling in D1R-expressing NAc neurons enhances morphine reward by reducing GABA inhibition. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2646-53. PMID 24853771 DOI: 10.1038/npp.2014.118  1
2014 Maze I, Chaudhury D, Dietz DM, Von Schimmelmann M, Kennedy PJ, Lobo MK, Sillivan SE, Miller ML, Bagot RC, Sun H, Turecki G, Neve RL, Hurd YL, Shen L, Han MH, et al. G9a influences neuronal subtype specification in striatum. Nature Neuroscience. 17: 533-9. PMID 24584053 DOI: 10.1038/nn.3670  1
2014 Gaspari S, Papachatzaki MM, Koo JW, Carr FB, Tsimpanouli ME, Stergiou E, Bagot RC, Ferguson D, Mouzon E, Chakravarty S, Deisseroth K, Lobo MK, Zachariou V. Nucleus accumbens-specific interventions in RGS9-2 activity modulate responses to morphine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1968-77. PMID 24561386 DOI: 10.1038/npp.2014.45  1
2014 Iñiguez SD, Alcantara LF, Warren BL, Riggs LM, Parise EM, Vialou V, Wright KN, Dayrit G, Nieto SJ, Wilkinson MB, Lobo MK, Neve RL, Nestler EJ, Bolaños-Guzmán CA. Fluoxetine exposure during adolescence alters responses to aversive stimuli in adulthood. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 1007-21. PMID 24431458 DOI: 10.1523/JNEUROSCI.5725-12.2014  1
2013 Lobo MK, Zaman S, Damez-Werno DM, Koo JW, Bagot RC, DiNieri JA, Nugent A, Finkel E, Chaudhury D, Chandra R, Riberio E, Rabkin J, Mouzon E, Cachope R, Cheer JF, et al. ΔFosB induction in striatal medium spiny neuron subtypes in response to chronic pharmacological, emotional, and optogenetic stimuli. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 18381-95. PMID 24259563 DOI: 10.1523/JNEUROSCI.1875-13.2013  1
2013 Volman SF, Lammel S, Margolis EB, Kim Y, Richard JM, Roitman MF, Lobo MK. New insights into the specificity and plasticity of reward and aversion encoding in the mesolimbic system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 17569-76. PMID 24198347 DOI: 10.1523/JNEUROSCI.3250-13.2013  1
2013 Lee BR, Ma YY, Huang YH, Wang X, Otaka M, Ishikawa M, Neumann PA, Graziane NM, Brown TE, Suska A, Guo C, Lobo MK, Sesack SR, Wolf ME, Nestler EJ, et al. Maturation of silent synapses in amygdala-accumbens projection contributes to incubation of cocaine craving. Nature Neuroscience. 16: 1644-51. PMID 24077564 DOI: 10.1038/nn.3533  1
2013 Chandra R, Lenz JD, Gancarz AM, Chaudhury D, Schroeder GL, Han MH, Cheer JF, Dietz DM, Lobo MK. Optogenetic inhibition of D1R containing nucleus accumbens neurons alters cocaine-mediated regulation of Tiam1. Frontiers in Molecular Neuroscience. 6: 13. PMID 23745104 DOI: 10.3389/fnmol.2013.00013  0.76
2013 Lenz JD, Lobo MK. Optogenetic insights into striatal function and behavior. Behavioural Brain Research. 255: 44-54. PMID 23628212 DOI: 10.1016/j.bbr.2013.04.018  1
2013 Thanos PK, Robison L, Nestler EJ, Kim R, Michaelides M, Lobo MK, Volkow ND. Mapping brain metabolic connectivity in awake rats with μPET and optogenetic stimulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 6343-9. PMID 23575833 DOI: 10.1523/JNEUROSCI.4997-12.2013  1
2013 Mason BL, Lobo MK, Parada LF, Lutter M. Trk B signaling in dopamine 1 receptor neurons regulates food intake and body weight. Obesity (Silver Spring, Md.). 21: 2372-6. PMID 23512795 DOI: 10.1002/oby.20382  1
2013 Smith RJ, Lobo MK, Spencer S, Kalivas PW. Cocaine-induced adaptations in D1 and D2 accumbens projection neurons (a dichotomy not necessarily synonymous with direct and indirect pathways). Current Opinion in Neurobiology. 23: 546-52. PMID 23428656 DOI: 10.1016/j.conb.2013.01.026  1
2013 Chaudhury D, Walsh JJ, Friedman AK, Juarez B, Ku SM, Koo JW, Ferguson D, Tsai HC, Pomeranz L, Christoffel DJ, Nectow AR, Ekstrand M, Domingos A, Mazei-Robison MS, Mouzon E, ... Lobo MK, et al. Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. Nature. 493: 532-6. PMID 23235832 DOI: 10.1038/nature11713  1
2012 Liu J, Dietz K, DeLoyht JM, Pedre X, Kelkar D, Kaur J, Vialou V, Lobo MK, Dietz DM, Nestler EJ, Dupree J, Casaccia P. Impaired adult myelination in the prefrontal cortex of socially isolated mice. Nature Neuroscience. 15: 1621-3. PMID 23143512 DOI: 10.1038/nn.3263  1
2012 Koo JW, Mazei-Robison MS, Chaudhury D, Juarez B, LaPlant Q, Ferguson D, Feng J, Sun H, Scobie KN, Damez-Werno D, Crumiller M, Ohnishi YN, Ohnishi YH, Mouzon E, Dietz DM, ... Lobo MK, et al. BDNF is a negative modulator of morphine action. Science (New York, N.Y.). 338: 124-8. PMID 23042896 DOI: 10.1126/science.1222265  1
2012 Dietz DM, Sun H, Lobo MK, Cahill ME, Chadwick B, Gao V, Koo JW, Mazei-Robison MS, Dias C, Maze I, Damez-Werno D, Dietz KC, Scobie KN, Ferguson D, Christoffel D, et al. Rac1 is essential in cocaine-induced structural plasticity of nucleus accumbens neurons. Nature Neuroscience. 15: 891-6. PMID 22522400 DOI: 10.1038/nn.3094  1
2012 Lobo MK, Nestler EJ, Covington HE. Potential utility of optogenetics in the study of depression. Biological Psychiatry. 71: 1068-74. PMID 22322104 DOI: 10.1016/j.biopsych.2011.12.026  1
2012 Lobo MK. Lighting up the brain's reward circuitry. Annals of the New York Academy of Sciences. 1260: 24-33. PMID 22243412 DOI: 10.1111/j.1749-6632.2011.06368.x  1
2011 Gutierrez R, Lobo MK, Zhang F, de Lecea L. Neural integration of reward, arousal, and feeding: recruitment of VTA, lateral hypothalamus, and ventral striatal neurons. Iubmb Life. 63: 824-30. PMID 21901814 DOI: 10.1002/iub.539  1
2011 Covington HE, Maze I, Sun H, Bomze HM, DeMaio KD, Wu EY, Dietz DM, Lobo MK, Ghose S, Mouzon E, Neve RL, Tamminga CA, Nestler EJ. A role for repressive histone methylation in cocaine-induced vulnerability to stress. Neuron. 71: 656-70. PMID 21867882 DOI: 10.1016/j.neuron.2011.06.007  1
2011 Lobo MK, Nestler EJ. The striatal balancing act in drug addiction: distinct roles of direct and indirect pathway medium spiny neurons. Frontiers in Neuroanatomy. 5: 41. PMID 21811439 DOI: 10.3389/fnana.2011.00041  1
2011 Wilkinson MB, Dias C, Magida J, Mazei-Robison M, Lobo M, Kennedy P, Dietz D, Covington H, Russo S, Neve R, Ghose S, Tamminga C, Nestler EJ. A novel role of the WNT-dishevelled-GSK3β signaling cascade in the mouse nucleus accumbens in a social defeat model of depression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 9084-92. PMID 21697359 DOI: 10.1523/JNEUROSCI.0039-11.2011  1
2010 Covington HE, Lobo MK, Maze I, Vialou V, Hyman JM, Zaman S, LaPlant Q, Mouzon E, Ghose S, Tamminga CA, Neve RL, Deisseroth K, Nestler EJ. Antidepressant effect of optogenetic stimulation of the medial prefrontal cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16082-90. PMID 21123555 DOI: 10.1523/JNEUROSCI.1731-10.2010  1
2010 Lobo MK, Covington HE, Chaudhury D, Friedman AK, Sun H, Damez-Werno D, Dietz DM, Zaman S, Koo JW, Kennedy PJ, Mouzon E, Mogri M, Neve RL, Deisseroth K, Han MH, et al. Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward. Science (New York, N.Y.). 330: 385-90. PMID 20947769 DOI: 10.1126/science.1188472  1
2010 Cao JL, Vialou VF, Lobo MK, Robison AJ, Neve RL, Cooper DC, Nestler EJ, Han MH. Essential role of the cAMP-cAMP response-element binding protein pathway in opiate-induced homeostatic adaptations of locus coeruleus neurons. Proceedings of the National Academy of Sciences of the United States of America. 107: 17011-6. PMID 20837544 DOI: 10.1073/pnas.1010077107  1
2009 Lobo MK. Molecular profiling of striatonigral and striatopallidal medium spiny neurons past, present, and future. International Review of Neurobiology. 89: 1-35. PMID 19900613 DOI: 10.1016/S0074-7742(09)89001-6  1
2008 Lobo MK, Yeh C, Yang XW. Pivotal role of early B-cell factor 1 in development of striatonigral medium spiny neurons in the matrix compartment. Journal of Neuroscience Research. 86: 2134-46. PMID 18338816 DOI: 10.1002/jnr.21666  1
2007 Lobo MK, Cui Y, Ostlund SB, Balleine BW, Yang XW. Genetic control of instrumental conditioning by striatopallidal neuron-specific S1P receptor Gpr6. Nature Neuroscience. 10: 1395-7. PMID 17934457 DOI: 10.1038/nn1987  1
2007 Hernández-Echeagaray E, Cepeda C, Ariano MA, Lobo MK, Sibley DR, Levine MS. Dopamine reduction of GABA currents in striatal medium-sized spiny neurons is mediated principally by the D(1) receptor subtype. Neurochemical Research. 32: 229-40. PMID 17031565 DOI: 10.1007/s11064-006-9141-8  1
2006 Lobo MK, Karsten SL, Gray M, Geschwind DH, Yang XW. FACS-array profiling of striatal projection neuron subtypes in juvenile and adult mouse brains. Nature Neuroscience. 9: 443-52. PMID 16491081 DOI: 10.1038/nn1654  1
2004 André VM, Flores-Hernández J, Cepeda C, Starling AJ, Nguyen S, Lobo MK, Vinters HV, Levine MS, Mathern GW. NMDA receptor alterations in neurons from pediatric cortical dysplasia tissue. Cerebral Cortex (New York, N.Y. : 1991). 14: 634-46. PMID 15054078 DOI: 10.1093/cercor/bhh024  1
2003 Lobo MK, Itri JN, Cepeda C, Chavira CA, Levine MS. Ionotropic glutamate receptor expression and dopaminergic modulation in the developing subthalamic nucleus of the rat: an immunohistochemical and electrophysiological analysis. Developmental Neuroscience. 25: 384-93. PMID 14966379 DOI: 10.1159/000075664  1
2000 Nansen EA, Jokel ES, Lobo MK, Micevych PE, Ariano MA, Levine MS. Striatal ionotropic glutamate receptor ontogeny in the rat. Developmental Neuroscience. 22: 329-40. PMID 10965155  1
Show low-probability matches.